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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for AIRE

Z-value: 2.36

Motif logo

Transcription factors associated with AIRE

Gene Symbol	Gene ID	Gene Info
AIRE Ensembl NCBI GeneCards UniProt	ENSG00000160224.12	AIRE

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
AIRE	chr21_45705593_45705882	26	0.954131	0.31	4.1e-01	Click!

Activity of the AIRE motif across conditions

Conditions sorted by the z-value of the AIRE motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_9882638_9884014	0.71	CLSTN1	calsyntenin 1	716	0.65
chr6_154726112_154726296	0.59	CNKSR3	CNKSR family member 3	25425	0.23
chr8_54817773_54817967	0.57	ENSG00000200528	.	9409	0.19
chr4_470311_470489	0.57	ZNF721	zinc finger protein 721	2444	0.24
chr7_120630679_120630951	0.57	CPED1	cadherin-like and PC-esterase domain containing 1	1139	0.51
chr14_45711437_45711895	0.57	MIS18BP1	MIS18 binding protein 1	10714	0.2
chr14_100260181_100260448	0.55	EML1	echinoderm microtubule associated protein like 1	542	0.83
chr1_217263352_217263815	0.53	ESRRG	estrogen-related receptor gamma	607	0.86
chr2_202901871_202902113	0.52	FZD7	frizzled family receptor 7	2682	0.25
chr12_50748152_50748528	0.52	FAM186A	family with sequence similarity 186, member A	3672	0.22
chr1_172113664_172113837	0.51	ENSG00000208024	.	34	0.69
chr5_121412020_121412268	0.51	LOX	lysyl oxidase	1836	0.4
chr3_15369209_15369360	0.51	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	4783	0.16
chr8_116675050_116675578	0.51	TRPS1	trichorhinophalangeal syndrome I	1409	0.6
chr20_50664340_50664598	0.51	ZFP64	ZFP64 zinc finger protein	50536	0.17
chr21_17443239_17443390	0.51	ENSG00000252273	.	35485	0.23
chr2_150903026_150903295	0.50	ENSG00000207270	.	435872	0.01
chr12_7037386_7038830	0.49	ATN1	atrophin 1	632	0.41
chr9_102829140_102829291	0.49	ERP44	endoplasmic reticulum protein 44	32107	0.16
chr8_104384541_104384884	0.48	CTHRC1	collagen triple helix repeat containing 1	51	0.97
chr19_34359259_34359976	0.47	ENSG00000240626	.	58913	0.13
chr1_243415347_243415602	0.46	CEP170	centrosomal protein 170kDa	1148	0.47
chr5_14443711_14444058	0.46	TRIO	trio Rho guanine nucleotide exchange factor	44673	0.2
chrX_14882707_14882858	0.45	FANCB	Fanconi anemia, complementation group B	8392	0.24
chr6_151392247_151392482	0.45	RP1-292B18.3		15171	0.18
chr14_51387153_51387346	0.45	RP11-218E20.5		8305	0.17
chr15_78594347_78594498	0.45	WDR61	WD repeat domain 61	2286	0.2
chr13_24146543_24146694	0.45	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1815	0.49
chrX_114467670_114468385	0.45	LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	601	0.77
chr3_173302379_173302636	0.44	NLGN1	neuroligin 1	162	0.98
chr19_11306068_11306280	0.44	KANK2	KN motif and ankyrin repeat domains 2	187	0.9
chr1_98514742_98514981	0.44	ENSG00000225206	.	3134	0.4
chr16_15588070_15588221	0.43	C16orf45	chromosome 16 open reading frame 45	7978	0.23
chr9_130615060_130615211	0.43	ENG	endoglin	1780	0.16
chr12_42978890_42979099	0.43	PRICKLE1	prickle homolog 1 (Drosophila)	4484	0.31
chr8_9413349_9414633	0.43	RP11-375N15.2		39	0.92
chr3_11651207_11651493	0.42	VGLL4	vestigial like 4 (Drosophila)	628	0.65
chr10_26846446_26846738	0.42	ENSG00000199733	.	48074	0.17
chrX_54947220_54948504	0.42	TRO	trophinin	41	0.97
chr11_63438034_63439177	0.42	ATL3	atlastin GTPase 3	479	0.76
chr2_38265076_38265999	0.42	RMDN2-AS1	RMDN2 antisense RNA 1	2053	0.33
chr9_97666762_97667035	0.42	RP11-49O14.2		4187	0.23
chr3_79066759_79066910	0.42	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	860	0.75
chr15_86194014_86194165	0.42	ENSG00000202081	.	770	0.54
chr11_114167265_114167463	0.42	NNMT	nicotinamide N-methyltransferase	721	0.72
chr16_10679196_10679376	0.42	EMP2	epithelial membrane protein 2	4731	0.2
chr18_43785173_43785324	0.41	C18orf25	chromosome 18 open reading frame 25	31248	0.18
chr8_142048186_142048475	0.41	PTK2	protein tyrosine kinase 2	36121	0.17
chr3_32728169_32728353	0.41	CNOT10	CCR4-NOT transcription complex, subunit 10	1405	0.51
chr15_95870278_95870659	0.41	ENSG00000222076	.	418565	0.01
chr5_72733592_72733937	0.41	FOXD1	forkhead box D1	10588	0.21
chr10_65275500_65275740	0.41	REEP3	receptor accessory protein 3	5503	0.26
chr1_163039219_163039545	0.41	RGS4	regulator of G-protein signaling 4	231	0.96
chr4_175750179_175750687	0.41	GLRA3	glycine receptor, alpha 3	32	0.99
chr11_108766543_108766821	0.41	ENSG00000201243	.	109562	0.07
chr12_12111873_12112098	0.41	ETV6	ets variant 6	73114	0.11
chr21_22548095_22548278	0.40	NCAM2	neural cell adhesion molecule 2	28748	0.23
chr14_73881950_73882101	0.40	NUMB	numb homolog (Drosophila)	5246	0.21
chr11_56981115_56981363	0.40	APLNR	apelin receptor	23436	0.16
chr15_96880068_96880219	0.40	ENSG00000222651	.	3653	0.19
chr5_89317042_89317197	0.40	ENSG00000264342	.	4582	0.37
chr4_74763571_74763722	0.40	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	28525	0.13
chr2_151424342_151424493	0.40	RND3	Rho family GTPase 3	28892	0.27
chr8_77596544_77596695	0.40	ZFHX4	zinc finger homeobox 4	603	0.65
chr2_47571438_47571633	0.40	EPCAM	epithelial cell adhesion molecule	762	0.64
chr7_70159815_70160908	0.39	AUTS2	autism susceptibility candidate 2	33764	0.25
chr10_74591963_74592114	0.39	OIT3	oncoprotein induced transcript 3	61301	0.1
chr8_136975571_136975722	0.39	ENSG00000199652	.	220908	0.02
chr10_95136415_95136839	0.39	MYOF	myoferlin	105324	0.06
chr9_109622995_109623671	0.39	ZNF462	zinc finger protein 462	2045	0.37
chr1_199824347_199824498	0.38	ENSG00000200139	.	32865	0.22
chr4_71570546_71572213	0.38	RUFY3	RUN and FYVE domain containing 3	861	0.36
chr4_41215270_41215769	0.38	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	956	0.59
chr1_157013915_157014350	0.38	ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	733	0.68
chr2_86225315_86225466	0.38	POLR1A	polymerase (RNA) I polypeptide A, 194kDa	107888	0.05
chr2_198539523_198539712	0.38	RFTN2	raftlin family member 2	1102	0.51
chr4_116139793_116139944	0.38	NDST4	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4	104836	0.08
chr8_107904204_107904364	0.38	ABRA	actin-binding Rho activating protein	121811	0.06
chr5_127981549_127981700	0.37	FBN2	fibrillin 2	13254	0.23
chr7_127318860_127319011	0.37	SND1	staphylococcal nuclease and tudor domain containing 1	26701	0.16
chr12_78334931_78335200	0.37	NAV3	neuron navigator 3	24991	0.28
chr9_16680814_16680965	0.37	BNC2	basonuclin 2	24191	0.21
chr13_37492943_37493377	0.37	SMAD9	SMAD family member 9	1215	0.52
chr1_192757431_192757794	0.37	RGS2	regulator of G-protein signaling 2, 24kDa	20559	0.24
chr2_38299955_38300348	0.37	CYP1B1-AS1	CYP1B1 antisense RNA 1	2640	0.23
chr7_93552303_93552503	0.37	GNG11	guanine nucleotide binding protein (G protein), gamma 11	1392	0.38
chr18_56121962_56122204	0.37	ENSG00000207778	.	3777	0.21
chr12_109079040_109079191	0.36	CORO1C	coronin, actin binding protein, 1C	11063	0.15
chr6_162052900_162053180	0.36	ENSG00000221021	.	16942	0.31
chr6_76645073_76645368	0.36	IMPG1	interphotoreceptor matrix proteoglycan 1	454	0.81
chr6_151392500_151392798	0.36	RP1-292B18.3		15456	0.18
chr7_116141197_116141631	0.36	CAV2	caveolin 2	1580	0.29
chr10_60198379_60198605	0.36	TFAM	transcription factor A, mitochondrial	53128	0.15
chr12_59398105_59398256	0.36	RP11-150C16.1		83760	0.1
chr22_46473276_46473626	0.36	FLJ27365	hsa-mir-4763	2741	0.14
chr4_77508066_77508217	0.35	ENSG00000265314	.	11437	0.17
chr3_75833792_75835020	0.35	ZNF717	zinc finger protein 717	151	0.97
chr6_16850081_16850303	0.35	RP1-151F17.1		88049	0.09
chr3_65744862_65745013	0.35	MAGI1-AS1	MAGI1 antisense RNA 1	134554	0.05
chr4_146855718_146855869	0.35	ZNF827	zinc finger protein 827	3830	0.28
chr3_32001250_32001418	0.35	OSBPL10	oxysterol binding protein-like 10	21458	0.18
chr6_57296683_57296834	0.35	ENSG00000212017	.	41828	0.2
chr12_59312115_59312531	0.35	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	1004	0.56
chr4_169614920_169615071	0.35	ENSG00000206613	.	7128	0.22
chr9_36277071_36277282	0.35	GNE	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	123	0.97
chr11_122037044_122037237	0.35	ENSG00000207994	.	14124	0.17
chr15_96889520_96889695	0.35	ENSG00000222651	.	13117	0.15
chr15_44196245_44196396	0.35	FRMD5	FERM domain containing 5	15380	0.15
chr7_22646904_22647055	0.35	AC002480.4		17655	0.17
chr9_126331371_126331654	0.35	ENSG00000222722	.	16224	0.24
chr5_98113295_98113446	0.34	RGMB	repulsive guidance molecule family member b	4031	0.25
chr2_191748635_191749149	0.34	AC005540.3		2107	0.33
chr1_60204181_60204332	0.34	ENSG00000266150	.	5288	0.28
chr6_83900430_83900634	0.34	PGM3	phosphoglucomutase 3	2168	0.3
chr2_192500334_192500574	0.34	NABP1	nucleic acid binding protein 1	42408	0.2
chr7_24972774_24972925	0.34	OSBPL3	oxysterol binding protein-like 3	15137	0.24
chr14_52925377_52925528	0.34	TXNDC16	thioredoxin domain containing 16	93771	0.07
chr1_114403266_114403417	0.34	AP4B1-AS1	AP4B1 antisense RNA 1	4084	0.15
chr13_74637272_74637666	0.34	KLF12	Kruppel-like factor 12	68283	0.14
chr7_27217405_27217623	0.34	RP1-170O19.20	Uncharacterized protein	2118	0.1
chr5_111110911_111111062	0.34	NREP	neuronal regeneration related protein	17071	0.21
chr5_155903124_155903466	0.34	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	149528	0.04
chr10_78924352_78924699	0.34	RP11-180I22.2		16475	0.25
chr19_58689540_58689691	0.34	ZNF274	zinc finger protein 274	4781	0.15
chr2_5835221_5835372	0.34	SOX11	SRY (sex determining region Y)-box 11	2497	0.27
chr13_45146605_45146867	0.34	TSC22D1	TSC22 domain family, member 1	3656	0.33
chr1_162603392_162603656	0.34	DDR2	discoidin domain receptor tyrosine kinase 2	1264	0.48
chr1_35688354_35688505	0.34	ENSG00000201868	.	26859	0.13
chr2_166430308_166430713	0.34	CSRNP3	cysteine-serine-rich nuclear protein 3	109	0.98
chr8_18578408_18578634	0.34	RP11-161I2.1		106	0.98
chr7_5673628_5673882	0.34	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	39438	0.12
chr13_33684806_33685110	0.34	STARD13-IT1	STARD13 intronic transcript 1 (non-protein coding)	53588	0.13
chr6_149256072_149256223	0.34	RP11-162J8.2		29673	0.23
chr8_6539493_6539644	0.34	CTD-2541M15.1		26132	0.18
chr1_170640402_170640573	0.34	PRRX1	paired related homeobox 1	7409	0.3
chr21_17442706_17442989	0.34	ENSG00000252273	.	35018	0.24
chr6_3910498_3910912	0.33	FAM50B	family with sequence similarity 50, member B	61083	0.1
chr9_12859535_12860149	0.33	ENSG00000222658	.	25478	0.2
chr9_114061539_114061711	0.33	OR2K2	olfactory receptor, family 2, subfamily K, member 2	29088	0.21
chr3_15598382_15598533	0.33	COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	35199	0.11
chr1_203482311_203482608	0.33	OPTC	opticin	17361	0.21
chr21_17584847_17584998	0.33	ENSG00000201025	.	72167	0.13
chr7_134464463_134465343	0.33	CALD1	caldesmon 1	474	0.89
chr8_128938937_128939156	0.33	TMEM75	transmembrane protein 75	21545	0.19
chr4_169553568_169553728	0.33	PALLD	palladin, cytoskeletal associated protein	880	0.63
chr7_19437447_19437598	0.33	FERD3L	Fer3-like bHLH transcription factor	252478	0.02
chr1_23066485_23066803	0.33	ENSG00000216157	.	8760	0.17
chr4_110223153_110224430	0.33	COL25A1	collagen, type XXV, alpha 1	8	0.99
chr10_77157105_77157688	0.33	ENSG00000237149	.	3881	0.22
chr7_27191312_27191528	0.33	HOXA-AS3	HOXA cluster antisense RNA 3	1749	0.13
chr21_28336747_28336898	0.33	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	2010	0.38
chr12_62998637_62998788	0.33	ENSG00000199179	.	1246	0.3
chr12_3001234_3001385	0.33	TULP3	tubby like protein 3	1236	0.31
chr6_28109319_28110552	0.33	ZKSCAN8	zinc finger with KRAB and SCAN domains 8	219	0.89
chr14_75515800_75515951	0.33	MLH3	mutL homolog 3	519	0.68
chr1_214551590_214551850	0.33	RP11-176D17.3		20762	0.23
chr2_161826657_161826810	0.33	ENSG00000244372	.	92675	0.09
chr2_210390985_210391683	0.32	MAP2	microtubule-associated protein 2	52705	0.18
chr17_65208623_65208774	0.32	RP11-401F2.4		11721	0.16
chr11_35035790_35035960	0.32	PDHX	pyruvate dehydrogenase complex, component X	36544	0.17
chr9_128235766_128235975	0.32	MAPKAP1	mitogen-activated protein kinase associated protein 1	10910	0.23
chr2_188353955_188354194	0.32	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	24294	0.21
chr19_56578206_56578448	0.32	ZNF787	zinc finger protein 787	36526	0.11
chr14_78073975_78074126	0.32	SPTLC2	serine palmitoyltransferase, long chain base subunit 2	9066	0.2
chr5_3597777_3597928	0.32	IRX1	iroquois homeobox 1	1684	0.41
chr7_67383536_67383687	0.32	ENSG00000265600	.	561944	0.0
chr12_2162213_2162837	0.32	CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	61	0.97
chr4_140926197_140926348	0.32	MAML3	mastermind-like 3 (Drosophila)	114151	0.06
chrX_34673939_34674563	0.32	TMEM47	transmembrane protein 47	1154	0.68
chr1_78472118_78472672	0.32	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	1857	0.26
chr1_205168795_205169031	0.32	DSTYK	dual serine/threonine and tyrosine protein kinase	11781	0.17
chr2_216294640_216294791	0.32	FN1	fibronectin 1	6075	0.23
chr17_27720697_27720848	0.32	TAOK1	TAO kinase 1	2823	0.15
chr15_77750021_77750172	0.32	HMG20A	high mobility group 20A	463	0.87
chr11_31005768_31005986	0.32	DCDC1	doublecortin domain containing 1	8356	0.32
chr16_55513844_55514378	0.31	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	201	0.95
chr1_103571993_103572213	0.31	COL11A1	collagen, type XI, alpha 1	1631	0.56
chr21_42662684_42662835	0.31	FAM3B	family with sequence similarity 3, member B	25902	0.18
chr17_45982661_45983102	0.31	SP2	Sp2 transcription factor	9365	0.1
chr2_45679896_45680047	0.31	SRBD1	S1 RNA binding domain 1	115183	0.06
chr4_187901481_187901677	0.31	ENSG00000252382	.	122969	0.06
chr12_15490173_15490332	0.31	RERG	RAS-like, estrogen-regulated, growth inhibitor	11280	0.23
chr7_116168289_116168733	0.31	CAV1	caveolin 1, caveolae protein, 22kDa	2164	0.26
chr5_141700452_141700811	0.31	SPRY4	sprouty homolog 4 (Drosophila)	3116	0.28
chr7_134465998_134466492	0.31	CALD1	caldesmon 1	1816	0.49
chr13_102050945_102051096	0.31	NALCN	sodium leak channel, non-selective	485	0.88
chr7_82072002_82072462	0.31	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	799	0.78
chr2_208122869_208123109	0.31	AC007879.5		4013	0.26
chr12_117037726_117037963	0.31	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2	24188	0.24
chr3_25470884_25471099	0.31	RARB	retinoic acid receptor, beta	1189	0.61
chr5_125960121_125960311	0.31	C5orf48	chromosome 5 open reading frame 48	7198	0.19
chr3_285704_285855	0.31	CHL1	cell adhesion molecule L1-like	26561	0.19
chr20_10340480_10340631	0.31	ENSG00000211588	.	2323	0.32
chr9_101803305_101803593	0.31	TGFBR1	transforming growth factor, beta receptor 1	62871	0.11
chr6_19691587_19692480	0.31	ENSG00000200957	.	49273	0.18
chr2_200310339_200310490	0.31	SATB2	SATB homeobox 2	10397	0.24
chr17_60868253_60868692	0.31	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	15529	0.23
chr19_55684291_55685412	0.31	SYT5	synaptotagmin V	1083	0.28
chr4_61549406_61549584	0.31	ENSG00000216027	.	19739	0.3
chr4_162635469_162635763	0.31	RP11-497K21.1		308269	0.01

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of AIRE

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.2	0.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	0.6	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.7	GO:0070208	protein heterotrimerization(GO:0070208)
0.2	0.5	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.2	0.5	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2	0.5	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.4	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.4	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.7	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.6	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.6	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.3	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.6	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.4	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.7	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.4	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.4	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.4	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.7	GO:0090103	cochlea morphogenesis(GO:0090103)
0.1	0.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.5	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1	0.2	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1	0.3	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.1	1.8	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.2	GO:0031223	response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.1	0.2	GO:0060023	soft palate development(GO:0060023)
0.1	0.1	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.2	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.4	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.1	GO:0072070	loop of Henle development(GO:0072070)
0.1	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.1	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.1	0.3	GO:0021670	lateral ventricle development(GO:0021670)
0.1	0.2	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.4	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.1	0.3	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.2	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.4	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.1	GO:0072189	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter development(GO:0072189) kidney smooth muscle tissue development(GO:0072194)
0.1	0.1	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.4	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.5	GO:0048844	artery morphogenesis(GO:0048844)
0.1	0.2	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.4	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1	0.4	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.1	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.2	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.1	0.2	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.2	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.3	GO:0015871	choline transport(GO:0015871)
0.0	0.3	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.3	GO:0042640	anagen(GO:0042640)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.3	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.2	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0002246	wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0060391	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.2	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.3	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0060900	optic cup morphogenesis involved in camera-type eye development(GO:0002072) embryonic camera-type eye formation(GO:0060900)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.2	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.5	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.5	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.1	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.2	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.2	GO:0003281	ventricular septum development(GO:0003281)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.3	GO:0060749	mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.3	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.4	GO:0007566	embryo implantation(GO:0007566)
0.0	0.6	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.6	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0002686	negative regulation of leukocyte migration(GO:0002686)
0.0	0.1	GO:2000794	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.0	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.1	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0002667	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0060087	relaxation of smooth muscle(GO:0044557) negative regulation of smooth muscle contraction(GO:0045986) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.1	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.1	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.2	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.5	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.3	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.2	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.2	GO:0045844	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	1.1	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.2	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.6	GO:0060606	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.0	GO:0043113	receptor clustering(GO:0043113)
0.0	0.9	GO:0034332	adherens junction organization(GO:0034332)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.2	GO:0006949	syncytium formation(GO:0006949)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:1903523	negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.0	0.1	GO:0051567	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.0	GO:2000757	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0019731	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.3	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.3	GO:0001942	hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405) skin epidermis development(GO:0098773)
0.0	0.0	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0043324	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.0	GO:0060911	cardiac cell fate commitment(GO:0060911)
0.0	0.2	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:0090102	cochlea development(GO:0090102)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0043049	otic placode formation(GO:0043049)
0.0	0.1	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.4	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.3	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:2000756	regulation of histone acetylation(GO:0035065) regulation of protein acetylation(GO:1901983) regulation of peptidyl-lysine acetylation(GO:2000756)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.0	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.2	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	1.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0045932	negative regulation of muscle contraction(GO:0045932)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.0	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.0	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.0	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.0	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.0	GO:0042723	vitamin transmembrane transport(GO:0035461) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.2	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.1	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.2	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.2	GO:0018904	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.5	GO:0005588	collagen type V trimer(GO:0005588)
0.2	1.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.7	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:0071437	invadopodium(GO:0071437)
0.1	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.4	GO:0005915	zonula adherens(GO:0005915)
0.1	0.5	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.4	GO:0001527	microfibril(GO:0001527)
0.1	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.5	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	1.0	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.6	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.3	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.4	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.6	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.4	GO:0031594	neuromuscular junction(GO:0031594)
0.0	1.2	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	1.3	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.7	GO:0044309	neuron spine(GO:0044309)
0.0	0.2	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	4.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.6	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.4	GO:0005902	microvillus(GO:0005902)
0.0	1.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.0	GO:0044447	axoneme part(GO:0044447)
0.0	0.2	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.9	GO:0030016	myofibril(GO:0030016)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2	0.5	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.7	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	1.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.4	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.3	GO:0003696	satellite DNA binding(GO:0003696)
0.1	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	1.6	GO:0045296	cadherin binding(GO:0045296)
0.1	0.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.4	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.3	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0070052	collagen V binding(GO:0070052)
0.1	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.5	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	1.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	1.9	GO:0005518	collagen binding(GO:0005518)
0.1	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.2	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.6	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.6	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.2	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	2.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.3	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.5	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.6	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.3	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.4	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.2	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.0	GO:0005497	androgen binding(GO:0005497)
0.0	0.2	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.4	GO:0019199	transmembrane receptor protein kinase activity(GO:0019199)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.3	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0005109	frizzled binding(GO:0005109)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	3.2	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.1	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	1.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.3	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	2.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.4	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.3	PID BMP PATHWAY	BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.6	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.8	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.4	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.1	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols