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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for AIRE

Z-value: 2.36

Motif logo

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Transcription factors associated with AIRE

Gene Symbol Gene ID Gene Info
AIRE
ENSG00000160224.12 autoimmune regulator

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr21_45705593_45705882AIRE260.9541310.314.1e-01Click!

Activity of the AIRE motif across conditions

Conditions sorted by the z-value of the AIRE motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_9882638_9884014 0.71 CLSTN1
 calsyntenin 1
 716
 0.65
chr6_154726112_154726296 0.59 CNKSR3
 CNKSR family member 3
 25425
 0.23
chr8_54817773_54817967 0.57 ENSG00000200528
 .
 9409
 0.19
chr4_470311_470489 0.57 ZNF721
 zinc finger protein 721
 2444
 0.24
chr7_120630679_120630951 0.57 CPED1
 cadherin-like and PC-esterase domain containing 1
 1139
 0.51
chr14_45711437_45711895 0.57 MIS18BP1
 MIS18 binding protein 1
 10714
 0.2
chr14_100260181_100260448 0.55 EML1
 echinoderm microtubule associated protein like 1
 542
 0.83
chr1_217263352_217263815 0.53 ESRRG
 estrogen-related receptor gamma
 607
 0.86
chr2_202901871_202902113 0.52 FZD7
 frizzled family receptor 7
 2682
 0.25
chr12_50748152_50748528 0.52 FAM186A
 family with sequence similarity 186, member A
 3672
 0.22
chr1_172113664_172113837 0.51 ENSG00000208024
 .
 34
 0.69
chr5_121412020_121412268 0.51 LOX
 lysyl oxidase
 1836
 0.4
chr3_15369209_15369360 0.51 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 4783
 0.16
chr8_116675050_116675578 0.51 TRPS1
 trichorhinophalangeal syndrome I
 1409
 0.6
chr20_50664340_50664598 0.51 ZFP64
 ZFP64 zinc finger protein
 50536
 0.17
chr21_17443239_17443390 0.51 ENSG00000252273
 .
 35485
 0.23
chr2_150903026_150903295 0.50 ENSG00000207270
 .
 435872
 0.01
chr12_7037386_7038830 0.49 ATN1
 atrophin 1
 632
 0.41
chr9_102829140_102829291 0.49 ERP44
 endoplasmic reticulum protein 44
 32107
 0.16
chr8_104384541_104384884 0.48 CTHRC1
 collagen triple helix repeat containing 1
 51
 0.97
chr19_34359259_34359976 0.47 ENSG00000240626
 .
 58913
 0.13
chr1_243415347_243415602 0.46 CEP170
 centrosomal protein 170kDa
 1148
 0.47
chr5_14443711_14444058 0.46 TRIO
 trio Rho guanine nucleotide exchange factor
 44673
 0.2
chrX_14882707_14882858 0.45 FANCB
 Fanconi anemia, complementation group B
 8392
 0.24
chr6_151392247_151392482 0.45 RP1-292B18.3
15171
 0.18
chr14_51387153_51387346 0.45 RP11-218E20.5
8305
 0.17
chr15_78594347_78594498 0.45 WDR61
 WD repeat domain 61
 2286
 0.2
chr13_24146543_24146694 0.45 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 1815
 0.49
chrX_114467670_114468385 0.45 LRCH2
 leucine-rich repeats and calponin homology (CH) domain containing 2
 601
 0.77
chr3_173302379_173302636 0.44 NLGN1
 neuroligin 1
 162
 0.98
chr19_11306068_11306280 0.44 KANK2
 KN motif and ankyrin repeat domains 2
 187
 0.9
chr1_98514742_98514981 0.44 ENSG00000225206
 .
 3134
 0.4
chr16_15588070_15588221 0.43 C16orf45
 chromosome 16 open reading frame 45
 7978
 0.23
chr9_130615060_130615211 0.43 ENG
 endoglin
 1780
 0.16
chr12_42978890_42979099 0.43 PRICKLE1
 prickle homolog 1 (Drosophila)
 4484
 0.31
chr8_9413349_9414633 0.43 RP11-375N15.2
39
 0.92
chr3_11651207_11651493 0.42 VGLL4
 vestigial like 4 (Drosophila)
 628
 0.65
chr10_26846446_26846738 0.42 ENSG00000199733
 .
 48074
 0.17
chrX_54947220_54948504 0.42 TRO
 trophinin
 41
 0.97
chr11_63438034_63439177 0.42 ATL3
 atlastin GTPase 3
 479
 0.76
chr2_38265076_38265999 0.42 RMDN2-AS1
 RMDN2 antisense RNA 1
 2053
 0.33
chr9_97666762_97667035 0.42 RP11-49O14.2
4187
 0.23
chr3_79066759_79066910 0.42 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
 860
 0.75
chr15_86194014_86194165 0.42 ENSG00000202081
 .
 770
 0.54
chr11_114167265_114167463 0.42 NNMT
 nicotinamide N-methyltransferase
 721
 0.72
chr16_10679196_10679376 0.42 EMP2
 epithelial membrane protein 2
 4731
 0.2
chr18_43785173_43785324 0.41 C18orf25
 chromosome 18 open reading frame 25
 31248
 0.18
chr8_142048186_142048475 0.41 PTK2
 protein tyrosine kinase 2
 36121
 0.17
chr3_32728169_32728353 0.41 CNOT10
 CCR4-NOT transcription complex, subunit 10
 1405
 0.51
chr15_95870278_95870659 0.41 ENSG00000222076
 .
 418565
 0.01
chr5_72733592_72733937 0.41 FOXD1
 forkhead box D1
 10588
 0.21
chr10_65275500_65275740 0.41 REEP3
 receptor accessory protein 3
 5503
 0.26
chr1_163039219_163039545 0.41 RGS4
 regulator of G-protein signaling 4
 231
 0.96
chr4_175750179_175750687 0.41 GLRA3
 glycine receptor, alpha 3
 32
 0.99
chr11_108766543_108766821 0.41 ENSG00000201243
 .
 109562
 0.07
chr12_12111873_12112098 0.41 ETV6
 ets variant 6
 73114
 0.11
chr21_22548095_22548278 0.40 NCAM2
 neural cell adhesion molecule 2
 28748
 0.23
chr14_73881950_73882101 0.40 NUMB
 numb homolog (Drosophila)
 5246
 0.21
chr11_56981115_56981363 0.40 APLNR
 apelin receptor
 23436
 0.16
chr15_96880068_96880219 0.40 ENSG00000222651
 .
 3653
 0.19
chr5_89317042_89317197 0.40 ENSG00000264342
 .
 4582
 0.37
chr4_74763571_74763722 0.40 CXCL1
 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
 28525
 0.13
chr2_151424342_151424493 0.40 RND3
 Rho family GTPase 3
 28892
 0.27
chr8_77596544_77596695 0.40 ZFHX4
 zinc finger homeobox 4
 603
 0.65
chr2_47571438_47571633 0.40 EPCAM
 epithelial cell adhesion molecule
 762
 0.64
chr7_70159815_70160908 0.39 AUTS2
 autism susceptibility candidate 2
 33764
 0.25
chr10_74591963_74592114 0.39 OIT3
 oncoprotein induced transcript 3
 61301
 0.1
chr8_136975571_136975722 0.39 ENSG00000199652
 .
 220908
 0.02
chr10_95136415_95136839 0.39 MYOF
 myoferlin
 105324
 0.06
chr9_109622995_109623671 0.39 ZNF462
 zinc finger protein 462
 2045
 0.37
chr1_199824347_199824498 0.38 ENSG00000200139
 .
 32865
 0.22
chr4_71570546_71572213 0.38 RUFY3
 RUN and FYVE domain containing 3
 861
 0.36
chr4_41215270_41215769 0.38 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 956
 0.59
chr1_157013915_157014350 0.38 ARHGEF11
 Rho guanine nucleotide exchange factor (GEF) 11
 733
 0.68
chr2_86225315_86225466 0.38 POLR1A
 polymerase (RNA) I polypeptide A, 194kDa
 107888
 0.05
chr2_198539523_198539712 0.38 RFTN2
 raftlin family member 2
 1102
 0.51
chr4_116139793_116139944 0.38 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
 104836
 0.08
chr8_107904204_107904364 0.38 ABRA
 actin-binding Rho activating protein
 121811
 0.06
chr5_127981549_127981700 0.37 FBN2
 fibrillin 2
 13254
 0.23
chr7_127318860_127319011 0.37 SND1
 staphylococcal nuclease and tudor domain containing 1
 26701
 0.16
chr12_78334931_78335200 0.37 NAV3
 neuron navigator 3
 24991
 0.28
chr9_16680814_16680965 0.37 BNC2
 basonuclin 2
 24191
 0.21
chr13_37492943_37493377 0.37 SMAD9
 SMAD family member 9
 1215
 0.52
chr1_192757431_192757794 0.37 RGS2
 regulator of G-protein signaling 2, 24kDa
 20559
 0.24
chr2_38299955_38300348 0.37 CYP1B1-AS1
 CYP1B1 antisense RNA 1
 2640
 0.23
chr7_93552303_93552503 0.37 GNG11
 guanine nucleotide binding protein (G protein), gamma 11
 1392
 0.38
chr18_56121962_56122204 0.37 ENSG00000207778
 .
 3777
 0.21
chr12_109079040_109079191 0.36 CORO1C
 coronin, actin binding protein, 1C
 11063
 0.15
chr6_162052900_162053180 0.36 ENSG00000221021
 .
 16942
 0.31
chr6_76645073_76645368 0.36 IMPG1
 interphotoreceptor matrix proteoglycan 1
 454
 0.81
chr6_151392500_151392798 0.36 RP1-292B18.3
15456
 0.18
chr7_116141197_116141631 0.36 CAV2
 caveolin 2
 1580
 0.29
chr10_60198379_60198605 0.36 TFAM
 transcription factor A, mitochondrial
 53128
 0.15
chr12_59398105_59398256 0.36 RP11-150C16.1
83760
 0.1
chr22_46473276_46473626 0.36 FLJ27365
 hsa-mir-4763
 2741
 0.14
chr4_77508066_77508217 0.35 ENSG00000265314
 .
 11437
 0.17
chr3_75833792_75835020 0.35 ZNF717
 zinc finger protein 717
 151
 0.97
chr6_16850081_16850303 0.35 RP1-151F17.1
88049
 0.09
chr3_65744862_65745013 0.35 MAGI1-AS1
 MAGI1 antisense RNA 1
 134554
 0.05
chr4_146855718_146855869 0.35 ZNF827
 zinc finger protein 827
 3830
 0.28
chr3_32001250_32001418 0.35 OSBPL10
 oxysterol binding protein-like 10
 21458
 0.18
chr6_57296683_57296834 0.35 ENSG00000212017
 .
 41828
 0.2
chr12_59312115_59312531 0.35 LRIG3
 leucine-rich repeats and immunoglobulin-like domains 3
 1004
 0.56
chr4_169614920_169615071 0.35 ENSG00000206613
 .
 7128
 0.22
chr9_36277071_36277282 0.35 GNE
 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
 123
 0.97
chr11_122037044_122037237 0.35 ENSG00000207994
 .
 14124
 0.17
chr15_96889520_96889695 0.35 ENSG00000222651
 .
 13117
 0.15
chr15_44196245_44196396 0.35 FRMD5
 FERM domain containing 5
 15380
 0.15
chr7_22646904_22647055 0.35 AC002480.4
17655
 0.17
chr9_126331371_126331654 0.35 ENSG00000222722
 .
 16224
 0.24
chr5_98113295_98113446 0.34 RGMB
 repulsive guidance molecule family member b
 4031
 0.25
chr2_191748635_191749149 0.34 AC005540.3
2107
 0.33
chr1_60204181_60204332 0.34 ENSG00000266150
 .
 5288
 0.28
chr6_83900430_83900634 0.34 PGM3
 phosphoglucomutase 3
 2168
 0.3
chr2_192500334_192500574 0.34 NABP1
 nucleic acid binding protein 1
 42408
 0.2
chr7_24972774_24972925 0.34 OSBPL3
 oxysterol binding protein-like 3
 15137
 0.24
chr14_52925377_52925528 0.34 TXNDC16
 thioredoxin domain containing 16
 93771
 0.07
chr1_114403266_114403417 0.34 AP4B1-AS1
 AP4B1 antisense RNA 1
 4084
 0.15
chr13_74637272_74637666 0.34 KLF12
 Kruppel-like factor 12
 68283
 0.14
chr7_27217405_27217623 0.34 RP1-170O19.20
 Uncharacterized protein
 2118
 0.1
chr5_111110911_111111062 0.34 NREP
 neuronal regeneration related protein
 17071
 0.21
chr5_155903124_155903466 0.34 SGCD
 sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
 149528
 0.04
chr10_78924352_78924699 0.34 RP11-180I22.2
16475
 0.25
chr19_58689540_58689691 0.34 ZNF274
 zinc finger protein 274
 4781
 0.15
chr2_5835221_5835372 0.34 SOX11
 SRY (sex determining region Y)-box 11
 2497
 0.27
chr13_45146605_45146867 0.34 TSC22D1
 TSC22 domain family, member 1
 3656
 0.33
chr1_162603392_162603656 0.34 DDR2
 discoidin domain receptor tyrosine kinase 2
 1264
 0.48
chr1_35688354_35688505 0.34 ENSG00000201868
 .
 26859
 0.13
chr2_166430308_166430713 0.34 CSRNP3
 cysteine-serine-rich nuclear protein 3
 109
 0.98
chr8_18578408_18578634 0.34 RP11-161I2.1
106
 0.98
chr7_5673628_5673882 0.34 FSCN1
 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
 39438
 0.12
chr13_33684806_33685110 0.34 STARD13-IT1
 STARD13 intronic transcript 1 (non-protein coding)
 53588
 0.13
chr6_149256072_149256223 0.34 RP11-162J8.2
29673
 0.23
chr8_6539493_6539644 0.34 CTD-2541M15.1
26132
 0.18
chr1_170640402_170640573 0.34 PRRX1
 paired related homeobox 1
 7409
 0.3
chr21_17442706_17442989 0.34 ENSG00000252273
 .
 35018
 0.24
chr6_3910498_3910912 0.33 FAM50B
 family with sequence similarity 50, member B
 61083
 0.1
chr9_12859535_12860149 0.33 ENSG00000222658
 .
 25478
 0.2
chr9_114061539_114061711 0.33 OR2K2
 olfactory receptor, family 2, subfamily K, member 2
 29088
 0.21
chr3_15598382_15598533 0.33 COLQ
 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
 35199
 0.11
chr1_203482311_203482608 0.33 OPTC
 opticin
 17361
 0.21
chr21_17584847_17584998 0.33 ENSG00000201025
 .
 72167
 0.13
chr7_134464463_134465343 0.33 CALD1
 caldesmon 1
 474
 0.89
chr8_128938937_128939156 0.33 TMEM75
 transmembrane protein 75
 21545
 0.19
chr4_169553568_169553728 0.33 PALLD
 palladin, cytoskeletal associated protein
 880
 0.63
chr7_19437447_19437598 0.33 FERD3L
 Fer3-like bHLH transcription factor
 252478
 0.02
chr1_23066485_23066803 0.33 ENSG00000216157
 .
 8760
 0.17
chr4_110223153_110224430 0.33 COL25A1
 collagen, type XXV, alpha 1
 8
 0.99
chr10_77157105_77157688 0.33 ENSG00000237149
 .
 3881
 0.22
chr7_27191312_27191528 0.33 HOXA-AS3
 HOXA cluster antisense RNA 3
 1749
 0.13
chr21_28336747_28336898 0.33 ADAMTS5
 ADAM metallopeptidase with thrombospondin type 1 motif, 5
 2010
 0.38
chr12_62998637_62998788 0.33 ENSG00000199179
 .
 1246
 0.3
chr12_3001234_3001385 0.33 TULP3
 tubby like protein 3
 1236
 0.31
chr6_28109319_28110552 0.33 ZKSCAN8
 zinc finger with KRAB and SCAN domains 8
 219
 0.89
chr14_75515800_75515951 0.33 MLH3
 mutL homolog 3
 519
 0.68
chr1_214551590_214551850 0.33 RP11-176D17.3
20762
 0.23
chr2_161826657_161826810 0.33 ENSG00000244372
 .
 92675
 0.09
chr2_210390985_210391683 0.32 MAP2
 microtubule-associated protein 2
 52705
 0.18
chr17_65208623_65208774 0.32 RP11-401F2.4
11721
 0.16
chr11_35035790_35035960 0.32 PDHX
 pyruvate dehydrogenase complex, component X
 36544
 0.17
chr9_128235766_128235975 0.32 MAPKAP1
 mitogen-activated protein kinase associated protein 1
 10910
 0.23
chr2_188353955_188354194 0.32 TFPI
 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
 24294
 0.21
chr19_56578206_56578448 0.32 ZNF787
 zinc finger protein 787
 36526
 0.11
chr14_78073975_78074126 0.32 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
 9066
 0.2
chr5_3597777_3597928 0.32 IRX1
 iroquois homeobox 1
 1684
 0.41
chr7_67383536_67383687 0.32 ENSG00000265600
 .
 561944
 0.0
chr12_2162213_2162837 0.32 CACNA1C
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 61
 0.97
chr4_140926197_140926348 0.32 MAML3
 mastermind-like 3 (Drosophila)
 114151
 0.06
chrX_34673939_34674563 0.32 TMEM47
 transmembrane protein 47
 1154
 0.68
chr1_78472118_78472672 0.32 DNAJB4
 DnaJ (Hsp40) homolog, subfamily B, member 4
 1857
 0.26
chr1_205168795_205169031 0.32 DSTYK
 dual serine/threonine and tyrosine protein kinase
 11781
 0.17
chr2_216294640_216294791 0.32 FN1
 fibronectin 1
 6075
 0.23
chr17_27720697_27720848 0.32 TAOK1
 TAO kinase 1
 2823
 0.15
chr15_77750021_77750172 0.32 HMG20A
 high mobility group 20A
 463
 0.87
chr11_31005768_31005986 0.32 DCDC1
 doublecortin domain containing 1
 8356
 0.32
chr16_55513844_55514378 0.31 MMP2
 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
 201
 0.95
chr1_103571993_103572213 0.31 COL11A1
 collagen, type XI, alpha 1
 1631
 0.56
chr21_42662684_42662835 0.31 FAM3B
 family with sequence similarity 3, member B
 25902
 0.18
chr17_45982661_45983102 0.31 SP2
 Sp2 transcription factor
 9365
 0.1
chr2_45679896_45680047 0.31 SRBD1
 S1 RNA binding domain 1
 115183
 0.06
chr4_187901481_187901677 0.31 ENSG00000252382
 .
 122969
 0.06
chr12_15490173_15490332 0.31 RERG
 RAS-like, estrogen-regulated, growth inhibitor
 11280
 0.23
chr7_116168289_116168733 0.31 CAV1
 caveolin 1, caveolae protein, 22kDa
 2164
 0.26
chr5_141700452_141700811 0.31 SPRY4
 sprouty homolog 4 (Drosophila)
 3116
 0.28
chr7_134465998_134466492 0.31 CALD1
 caldesmon 1
 1816
 0.49
chr13_102050945_102051096 0.31 NALCN
 sodium leak channel, non-selective
 485
 0.88
chr7_82072002_82072462 0.31 CACNA2D1
 calcium channel, voltage-dependent, alpha 2/delta subunit 1
 799
 0.78
chr2_208122869_208123109 0.31 AC007879.5
4013
 0.26
chr12_117037726_117037963 0.31 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 24188
 0.24
chr3_25470884_25471099 0.31 RARB
 retinoic acid receptor, beta
 1189
 0.61
chr5_125960121_125960311 0.31 C5orf48
 chromosome 5 open reading frame 48
 7198
 0.19
chr3_285704_285855 0.31 CHL1
 cell adhesion molecule L1-like
 26561
 0.19
chr20_10340480_10340631 0.31 ENSG00000211588
 .
 2323
 0.32
chr9_101803305_101803593 0.31 TGFBR1
 transforming growth factor, beta receptor 1
 62871
 0.11
chr6_19691587_19692480 0.31 ENSG00000200957
 .
 49273
 0.18
chr2_200310339_200310490 0.31 SATB2
 SATB homeobox 2
 10397
 0.24
chr17_60868253_60868692 0.31 MARCH10
 membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
 15529
 0.23
chr19_55684291_55685412 0.31 SYT5
 synaptotagmin V
 1083
 0.28
chr4_61549406_61549584 0.31 ENSG00000216027
 .
 19739
 0.3
chr4_162635469_162635763 0.31 RP11-497K21.1
308269
 0.01

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of AIRE

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.2 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.6 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.5 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.2 0.5 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.5 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.4 GO:0008049 male courtship behavior(GO:0008049)
0.1 0.4 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.4 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.3 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.6 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.4 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.4 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.4 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.7 GO:0090103 cochlea morphogenesis(GO:0090103)
0.1 0.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.5 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 1.8 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.2 GO:0031223 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.1 0.2 GO:0060023 soft palate development(GO:0060023)
0.1 0.1 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.2 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.1 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.1 0.3 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.4 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.1 0.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.1 GO:0072189 positive regulation of smooth muscle cell differentiation(GO:0051152) ureter development(GO:0072189) kidney smooth muscle tissue development(GO:0072194)
0.1 0.1 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.5 GO:0048844 artery morphogenesis(GO:0048844)
0.1 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.4 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1 0.4 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.2 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0042640 anagen(GO:0042640)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.2 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.1 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0002246 wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0060391 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.2 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0060900 optic cup morphogenesis involved in camera-type eye development(GO:0002072) embryonic camera-type eye formation(GO:0060900)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.2 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.5 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.5 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.3 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.1 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.0 GO:0060068 vagina development(GO:0060068)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0060087 relaxation of smooth muscle(GO:0044557) negative regulation of smooth muscle contraction(GO:0045986) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.1 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.2 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.5 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.2 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.2 GO:0045844 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 1.1 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.6 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.0 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0043113 receptor clustering(GO:0043113)
0.0 0.9 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0006949 syncytium formation(GO:0006949)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.0 0.1 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.3 GO:0001942 hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405) skin epidermis development(GO:0098773)
0.0 0.0 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.0 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.0 GO:0060911 cardiac cell fate commitment(GO:0060911)
0.0 0.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0090102 cochlea development(GO:0090102)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0043049 otic placode formation(GO:0043049)
0.0 0.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:2000756 regulation of histone acetylation(GO:0035065) regulation of protein acetylation(GO:1901983) regulation of peptidyl-lysine acetylation(GO:2000756)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.0 GO:0045932 negative regulation of muscle contraction(GO:0045932)
0.0 0.1 GO:0030539 male genitalia development(GO:0030539)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.0 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.0 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.0 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.0 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0042723 vitamin transmembrane transport(GO:0035461) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.2 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.1 GO:0090659 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.0 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0071437 invadopodium(GO:0071437)
0.1 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0005915 zonula adherens(GO:0005915)
0.1 0.5 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.4 GO:0001527 microfibril(GO:0001527)
0.1 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0043034 costamere(GO:0043034)
0.0 1.0 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.6 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0043205 fibril(GO:0043205)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.2 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 1.3 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.7 GO:0044309 neuron spine(GO:0044309)
0.0 0.2 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 4.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.0 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.9 GO:0030016 myofibril(GO:0030016)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.4 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.6 GO:0045296 cadherin binding(GO:0045296)
0.1 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 1.9 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.4 GO:0019199 transmembrane receptor protein kinase activity(GO:0019199)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 PID SHP2 PATHWAY SHP2 signaling
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.0 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.1 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols