Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for ALX3

Z-value: 0.86

Motif logo

logo of

Transcription factors associated with ALX3

Gene Symbol Gene ID Gene Info
ALX3
ENSG00000156150.6 ALX homeobox 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_110610926_110611170ALX322740.2029080.684.4e-02Click!
chr1_110612851_110613002ALX33960.7806080.531.4e-01Click!
chr1_110610618_110610769ALX326290.1834850.501.7e-01Click!
chr1_110611302_110611453ALX319450.2294620.442.3e-01Click!
chr1_110611525_110611676ALX317220.2548440.442.4e-01Click!

Activity of the ALX3 motif across conditions

Conditions sorted by the z-value of the ALX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_58055562_58056142 0.64 RP11-479O16.1
24754
 0.24
chr7_123390243_123390394 0.58 RP11-390E23.6
1196
 0.34
chr12_66583583_66583798 0.52 IRAK3
 interleukin-1 receptor-associated kinase 3
 653
 0.67
chr6_130391698_130391967 0.51 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
 50130
 0.15
chr20_21080465_21081932 0.49 ENSG00000199509
 .
 38517
 0.18
chr7_37724366_37724517 0.48 GPR141
 G protein-coupled receptor 141
 966
 0.42
chr8_95941010_95941161 0.42 TP53INP1
 tumor protein p53 inducible nuclear protein 1
 12116
 0.13
chr7_32929941_32930760 0.42 KBTBD2
 kelch repeat and BTB (POZ) domain containing 2
 415
 0.87
chrX_78400540_78401325 0.39 GPR174
 G protein-coupled receptor 174
 25537
 0.27
chr13_41555714_41555943 0.39 ELF1
 E74-like factor 1 (ets domain transcription factor)
 590
 0.77
chr13_31309966_31310295 0.37 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 485
 0.88
chr1_200865204_200865355 0.37 C1orf106
 chromosome 1 open reading frame 106
 1330
 0.42
chr11_118134576_118134833 0.37 MPZL2
 myelin protein zero-like 2
 293
 0.86
chr17_56362337_56362534 0.37 MPO
 myeloperoxidase
 4139
 0.15
chr10_30745504_30745655 0.37 MAP3K8
 mitogen-activated protein kinase kinase kinase 8
 17828
 0.21
chr21_15917916_15918619 0.37 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 395
 0.89
chr5_126094279_126094440 0.36 ENSG00000252185
 .
 3250
 0.29
chr4_147027155_147027306 0.36 ENSG00000216055
 .
 16206
 0.24
chr4_40630076_40630227 0.36 RBM47
 RNA binding motif protein 47
 1730
 0.47
chr4_36245078_36245884 0.36 ARAP2
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
 80
 0.74
chr12_10019991_10020525 0.35 RP11-290C10.1
632
 0.61
chr15_52844361_52844512 0.35 ARPP19
 cAMP-regulated phosphoprotein, 19kDa
 5505
 0.2
chr2_103506378_103506656 0.35 TMEM182
 transmembrane protein 182
 128045
 0.06
chr20_47448799_47448989 0.35 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 4474
 0.31
chr16_88987498_88987922 0.35 RP11-830F9.7
16454
 0.11
chr8_56831708_56831859 0.35 ENSG00000216204
 .
 10263
 0.14
chr2_70780238_70780449 0.34 TGFA
 transforming growth factor, alpha
 279
 0.93
chr10_129861850_129862130 0.34 PTPRE
 protein tyrosine phosphatase, receptor type, E
 16156
 0.26
chr1_8441651_8441802 0.34 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 16828
 0.17
chr6_133069776_133069927 0.34 RP1-55C23.7
3963
 0.15
chr16_31271922_31272073 0.34 ITGAM
 integrin, alpha M (complement component 3 receptor 3 subunit)
 682
 0.53
chr22_40858929_40859404 0.34 MKL1
 megakaryoblastic leukemia (translocation) 1
 256
 0.92
chr20_52271481_52272252 0.33 ENSG00000238468
 .
 13431
 0.22
chr2_61111507_61111691 0.33 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
 2808
 0.27
chr13_73631347_73631498 0.33 KLF5
 Kruppel-like factor 5 (intestinal)
 1508
 0.47
chr1_234735009_234735261 0.32 ENSG00000212144
 .
 6114
 0.19
chr12_10281805_10282201 0.32 CLEC7A
 C-type lectin domain family 7, member A
 678
 0.6
chr12_27150397_27150548 0.32 TM7SF3
 transmembrane 7 superfamily member 3
 2271
 0.24
chr3_187491387_187491633 0.32 BCL6
 B-cell CLL/lymphoma 6
 27995
 0.2
chr5_68905149_68905341 0.32 RP11-848G14.2
8895
 0.19
chr9_93557702_93558119 0.32 SYK
 spleen tyrosine kinase
 6159
 0.34
chr5_67562966_67563283 0.32 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 12944
 0.27
chr15_52023462_52024365 0.31 LYSMD2
 LysM, putative peptidoglycan-binding, domain containing 2
 6405
 0.15
chr5_57787350_57787738 0.31 GAPT
 GRB2-binding adaptor protein, transmembrane
 280
 0.92
chr15_69074948_69075145 0.31 ENSG00000265195
 .
 19218
 0.22
chr4_105887659_105887892 0.31 ENSG00000251906
 .
 8044
 0.31
chr11_128589269_128589524 0.31 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 23478
 0.17
chr14_75885513_75886422 0.31 RP11-293M10.6
8426
 0.2
chr2_153267501_153267713 0.30 FMNL2
 formin-like 2
 75856
 0.12
chr7_37726318_37726469 0.30 GPR141
 G protein-coupled receptor 141
 2918
 0.28
chr21_39630264_39630415 0.30 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 1469
 0.53
chr1_158802859_158803010 0.30 MNDA
 myeloid cell nuclear differentiation antigen
 1827
 0.35
chr5_70314152_70314347 0.30 NAIP
 NLR family, apoptosis inhibitory protein
 2288
 0.36
chr15_43531850_43532099 0.30 ENSG00000202211
 .
 7904
 0.13
chr5_17282868_17283019 0.30 ENSG00000252908
 .
 42223
 0.15
chr2_64864648_64864996 0.29 SERTAD2
 SERTA domain containing 2
 16225
 0.22
chr2_70157637_70157788 0.29 MXD1
 MAX dimerization protein 1
 15392
 0.11
chr12_8666250_8666401 0.29 CLEC4D
 C-type lectin domain family 4, member D
 189
 0.93
chr10_12064652_12064803 0.29 UPF2
 UPF2 regulator of nonsense transcripts homolog (yeast)
 13169
 0.19
chr11_33284734_33284885 0.29 HIPK3
 homeodomain interacting protein kinase 3
 4932
 0.25
chr5_69760327_69760484 0.29 RP11-497H16.7
8870
 0.28
chr7_115668295_115668446 0.29 TFEC
 transcription factor EC
 2425
 0.43
chr7_105912156_105912307 0.29 NAMPT
 nicotinamide phosphoribosyltransferase
 13136
 0.21
chr9_77757026_77757296 0.29 ENSG00000200041
 .
 39376
 0.14
chr11_640631_640896 0.29 DRD4
 dopamine receptor D4
 3470
 0.1
chr2_202076992_202077403 0.29 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 20969
 0.15
chr2_158299843_158300108 0.29 CYTIP
 cytohesin 1 interacting protein
 679
 0.68
chr3_98480702_98481101 0.29 ST3GAL6
 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
 1260
 0.48
chr1_112013416_112013602 0.28 C1orf162
 chromosome 1 open reading frame 162
 2905
 0.14
chr7_106507057_106507208 0.28 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
 1208
 0.59
chr1_36500237_36500507 0.28 RP4-665N4.8
21141
 0.16
chrX_133523066_133523217 0.28 ENSG00000251962
 .
 14271
 0.17
chr8_27223967_27224118 0.27 PTK2B
 protein tyrosine kinase 2 beta
 14126
 0.22
chr19_2267105_2267256 0.27 OAZ1
 ornithine decarboxylase antizyme 1
 2305
 0.12
chr13_68202936_68203087 0.27 PCDH9
 protocadherin 9
 398543
 0.01
chr4_1581349_1582263 0.27 FAM53A
 family with sequence similarity 53, member A
 75329
 0.08
chr12_64852912_64853865 0.27 TBK1
 TANK-binding kinase 1
 7133
 0.2
chr3_134261756_134261907 0.27 CEP63
 centrosomal protein 63kDa
 3167
 0.29
chr20_48328141_48328292 0.27 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
 2199
 0.3
chr11_46581548_46581763 0.27 AMBRA1
 autophagy/beclin-1 regulator 1
 31259
 0.15
chr8_112438072_112438223 0.26 ENSG00000222146
 .
 722907
 0.0
chr13_32616629_32616780 0.26 FRY-AS1
 FRY antisense RNA 1
 10928
 0.22
chr7_87503109_87503295 0.26 DBF4
 DBF4 homolog (S. cerevisiae)
 2342
 0.29
chr3_47123794_47124082 0.26 ENSG00000251938
 .
 6160
 0.22
chr1_207228136_207228287 0.26 PFKFB2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
 166
 0.92
chr10_17269607_17270502 0.26 VIM
 vimentin
 204
 0.89
chr17_29636179_29636457 0.26 EVI2B
 ecotropic viral integration site 2B
 4784
 0.15
chr4_84161976_84162127 0.26 COQ2
 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
 43867
 0.16
chr3_187492063_187492306 0.25 BCL6
 B-cell CLL/lymphoma 6
 28669
 0.2
chr9_129253296_129253447 0.25 ENSG00000221768
 .
 39899
 0.15
chr16_48411039_48411308 0.25 SIAH1
 siah E3 ubiquitin protein ligase 1
 8188
 0.18
chr17_78755045_78755196 0.25 RP11-28G8.1
24312
 0.21
chr12_64798382_64799443 0.25 XPOT
 exportin, tRNA
 86
 0.97
chr8_22961002_22961301 0.25 TNFRSF10C
 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
 717
 0.58
chr2_103048870_103049021 0.25 ENSG00000264764
 .
 196
 0.9
chr21_36772703_36772854 0.25 ENSG00000211590
 .
 320235
 0.01
chr7_105953972_105954204 0.25 NAMPT
 nicotinamide phosphoribosyltransferase
 27316
 0.2
chr2_207998546_207999225 0.25 KLF7
 Kruppel-like factor 7 (ubiquitous)
 24
 0.98
chr22_31615175_31615326 0.24 ENSG00000199695
 .
 3589
 0.13
chr6_11350314_11350465 0.24 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 32143
 0.22
chr13_86159310_86159559 0.24 ENSG00000207012
 .
 446
 0.91
chr22_17598033_17598230 0.24 CECR6
 cat eye syndrome chromosome region, candidate 6
 4012
 0.17
chr3_138524893_138525044 0.24 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 28626
 0.22
chr12_32742094_32742245 0.24 FGD4
 FYVE, RhoGEF and PH domain containing 4
 9291
 0.26
chr5_76112526_76112677 0.24 F2RL1
 coagulation factor II (thrombin) receptor-like 1
 2157
 0.27
chr1_192776419_192777001 0.24 RGS2
 regulator of G-protein signaling 2, 24kDa
 1461
 0.52
chr2_182168845_182168996 0.24 ENSG00000266705
 .
 1459
 0.58
chrX_19703578_19703729 0.24 SH3KBP1
 SH3-domain kinase binding protein 1
 14537
 0.29
chr11_33912422_33912614 0.24 LMO2
 LIM domain only 2 (rhombotin-like 1)
 1318
 0.47
chr10_70850849_70851349 0.24 SRGN
 serglycin
 3225
 0.25
chr20_52370901_52371111 0.24 ENSG00000238468
 .
 85709
 0.09
chr7_17039488_17039788 0.24 AGR3
 anterior gradient 3
 118027
 0.06
chr7_20825937_20826584 0.24 SP8
 Sp8 transcription factor
 245
 0.96
chr18_3453699_3454909 0.24 TGIF1
 TGFB-induced factor homeobox 1
 532
 0.8
chr8_26184784_26184935 0.24 PPP2R2A
 protein phosphatase 2, regulatory subunit B, alpha
 33860
 0.18
chr8_56792958_56793527 0.24 LYN
 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
 848
 0.55
chr11_72700714_72700865 0.23 FCHSD2
 FCH and double SH3 domains 2
 732
 0.75
chr12_25208788_25208939 0.23 LRMP
 lymphoid-restricted membrane protein
 3189
 0.26
chr15_38376930_38377081 0.23 TMCO5A
 transmembrane and coiled-coil domains 5A
 149547
 0.04
chr1_226251298_226251924 0.23 H3F3A
 H3 histone, family 3A
 67
 0.97
chr10_17395409_17395560 0.23 ST8SIA6
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
 26376
 0.16
chr1_221173678_221173829 0.23 HLX
 H2.0-like homeobox
 119169
 0.06
chr7_133456734_133456885 0.23 EXOC4
 exocyst complex component 4
 158413
 0.04
chr6_159071306_159071615 0.23 SYTL3
 synaptotagmin-like 3
 414
 0.83
chr9_132807889_132808048 0.23 FNBP1
 formin binding protein 1
 2495
 0.28
chr21_30543274_30543425 0.23 ENSG00000212479
 .
 9611
 0.13
chr8_131206424_131206650 0.23 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 13429
 0.23
chr20_1550627_1550778 0.23 SIRPB1
 signal-regulatory protein beta 1
 1856
 0.26
chr1_42230520_42230906 0.23 ENSG00000264896
 .
 5901
 0.3
chr14_70111468_70111619 0.22 KIAA0247
 KIAA0247
 33230
 0.18
chr2_178249081_178249232 0.22 AGPS
 alkylglycerone phosphate synthase
 8216
 0.14
chr2_201238626_201239302 0.22 ENSG00000201649
 .
 1066
 0.5
chr6_18391062_18391213 0.22 RNF144B
 ring finger protein 144B
 3556
 0.26
chr16_50059050_50060305 0.22 CNEP1R1
 CTD nuclear envelope phosphatase 1 regulatory subunit 1
 246
 0.93
chr21_36367168_36367319 0.22 RUNX1
 runt-related transcription factor 1
 54219
 0.18
chr7_5594421_5594572 0.22 CTB-161C1.1
1866
 0.25
chr6_107297762_107297913 0.22 C6orf203
 chromosome 6 open reading frame 203
 51570
 0.14
chr19_6425167_6425318 0.22 KHSRP
 KH-type splicing regulatory protein
 437
 0.66
chr9_139434770_139435052 0.22 RP11-413M3.4
2422
 0.15
chr7_37011253_37011404 0.22 ELMO1
 engulfment and cell motility 1
 13337
 0.2
chr6_41528112_41529137 0.22 FOXP4
 forkhead box P4
 4863
 0.19
chr8_12589361_12589512 0.22 LONRF1
 LON peptidase N-terminal domain and ring finger 1
 2540
 0.26
chr10_119644806_119644957 0.22 RP11-354M20.3
132117
 0.05
chr2_215664874_215665025 0.22 BARD1
 BRCA1 associated RING domain 1
 9448
 0.21
chr6_134551187_134551338 0.22 ENSG00000238631
 .
 23610
 0.16
chr5_148189087_148189390 0.22 ADRB2
 adrenoceptor beta 2, surface
 16918
 0.25
chr10_70087727_70088191 0.21 HNRNPH3
 heterogeneous nuclear ribonucleoprotein H3 (2H9)
 3873
 0.2
chr20_46412966_46413363 0.21 SULF2
 sulfatase 2
 1069
 0.59
chr7_50348449_50348781 0.21 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 297
 0.94
chr10_126664611_126664762 0.21 RP11-298J20.3
29685
 0.14
chr13_71409756_71409907 0.21 ENSG00000202433
 .
 376235
 0.01
chr3_50658137_50658523 0.21 MAPKAPK3
 mitogen-activated protein kinase-activated protein kinase 3
 3509
 0.19
chr3_108988766_108988917 0.21 ENSG00000252889
 .
 44865
 0.15
chr1_200987607_200987758 0.21 KIF21B
 kinesin family member 21B
 4854
 0.21
chr15_45940670_45940821 0.21 SQRDL
 sulfide quinone reductase-like (yeast)
 2666
 0.28
chr13_78434617_78434768 0.21 EDNRB
 endothelin receptor type B
 58253
 0.12
chr12_54891959_54892179 0.21 NCKAP1L
 NCK-associated protein 1-like
 499
 0.73
chr1_173807426_173807577 0.21 DARS2
 aspartyl-tRNA synthetase 2, mitochondrial
 13704
 0.1
chr8_9005081_9005340 0.21 PPP1R3B
 protein phosphatase 1, regulatory subunit 3B
 2996
 0.21
chr15_94796301_94796468 0.21 MCTP2
 multiple C2 domains, transmembrane 2
 21617
 0.29
chr7_139555611_139555822 0.21 TBXAS1
 thromboxane A synthase 1 (platelet)
 26606
 0.23
chr3_122029046_122029197 0.21 CSTA
 cystatin A (stefin A)
 14970
 0.16
chr11_59949160_59949311 0.21 MS4A6A
 membrane-spanning 4-domains, subfamily A, member 6A
 96
 0.97
chr1_169679248_169679951 0.21 SELL
 selectin L
 1240
 0.48
chr12_12510418_12511218 0.21 LOH12CR1
 loss of heterozygosity, 12, chromosomal region 1
 466
 0.63
chr5_39412000_39412151 0.21 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 12895
 0.26
chr22_36843986_36844137 0.21 ENSG00000252225
 .
 7046
 0.15
chr3_194821900_194822051 0.21 XXYLT1-AS1
 XXYLT1 antisense RNA 1
 6658
 0.17
chr4_139635357_139635508 0.21 ENSG00000238971
 .
 97488
 0.08
chr1_225610206_225610357 0.21 LBR
 lamin B receptor
 5318
 0.2
chr11_14375529_14375805 0.21 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 379
 0.91
chr3_58341767_58341918 0.21 PXK
 PX domain containing serine/threonine kinase
 22809
 0.17
chr9_85107233_85107384 0.21 SPATA31D1
 SPATA31 subfamily D, member 1
 503621
 0.0
chr19_13208223_13208471 0.20 LYL1
 lymphoblastic leukemia derived sequence 1
 5334
 0.11
chr4_68636095_68636246 0.20 GNRHR
 gonadotropin-releasing hormone receptor
 16092
 0.17
chr5_96297085_96297358 0.20 ENSG00000200884
 .
 1240
 0.43
chr13_99910339_99910626 0.20 GPR18
 G protein-coupled receptor 18
 146
 0.96
chr19_19083033_19083500 0.20 ENSG00000241172
 .
 14199
 0.1
chr14_88471433_88472132 0.20 GPR65
 G protein-coupled receptor 65
 314
 0.88
chr9_141104243_141104394 0.20 TUBBP5
 tubulin, beta pseudogene 5
 34821
 0.19
chr8_131290835_131290986 0.20 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 31622
 0.23
chr7_83932213_83932364 0.20 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 107527
 0.08
chr1_29253817_29254129 0.20 EPB41
 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
 12882
 0.18
chr2_148386736_148386887 0.20 ENSG00000253083
 .
 84312
 0.09
chr4_87930908_87931059 0.20 AFF1
 AF4/FMR2 family, member 1
 2562
 0.39
chr9_20490881_20491032 0.20 ENSG00000264941
 .
 11384
 0.23
chr4_79473579_79473973 0.20 ANXA3
 annexin A3
 655
 0.79
chr17_56736328_56736479 0.20 ENSG00000202077
 .
 263
 0.86
chr15_99444137_99444307 0.20 RP11-654A16.1
7458
 0.22
chr8_102506754_102506905 0.20 GRHL2
 grainyhead-like 2 (Drosophila)
 1843
 0.34
chr9_101881133_101881552 0.20 TGFBR1
 transforming growth factor, beta receptor 1
 8715
 0.21
chr2_149863937_149864088 0.20 LYPD6B
 LY6/PLAUR domain containing 6B
 30969
 0.22
chr6_6396318_6396469 0.20 F13A1
 coagulation factor XIII, A1 polypeptide
 75147
 0.11
chr12_100522777_100522928 0.20 UHRF1BP1L
 UHRF1 binding protein 1-like
 13773
 0.13
chr3_15336001_15336152 0.20 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 18524
 0.13
chr3_136557614_136557868 0.20 RP11-731C17.2
122
 0.96
chr5_88484775_88484926 0.20 MEF2C-AS1
 MEF2C antisense RNA 1
 223158
 0.02
chr14_68320261_68320412 0.20 RAD51B
 RAD51 paralog B
 30075
 0.16
chr2_70368629_70369219 0.20 C2orf42
 chromosome 2 open reading frame 42
 40203
 0.11
chr14_32555117_32555268 0.20 ARHGAP5
 Rho GTPase activating protein 5
 7755
 0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.2 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.2 GO:0001821 histamine secretion(GO:0001821)
0.1 0.2 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1 0.2 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.2 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.2 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.2 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0002902 regulation of B cell apoptotic process(GO:0002902)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.0 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0031394 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.2 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0071675 mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0002669 lymphocyte anergy(GO:0002249) T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0034776 response to histamine(GO:0034776)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.0 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.0 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0044116 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) negative regulation of growth of symbiont in host(GO:0044130) modulation of growth of symbiont involved in interaction with host(GO:0044144) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.0 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.3 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0048668 collateral sprouting(GO:0048668)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0001846 opsonin binding(GO:0001846)
0.1 0.2 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.1 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.3 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0052742 phosphatidylinositol kinase activity(GO:0052742)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.2 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation