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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ARNT

Z-value: 1.25

Motif logo

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Transcription factors associated with ARNT

Gene Symbol Gene ID Gene Info
ENSG00000143437.16 ARNT

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ARNTchr1_150848247_1508484796920.5784140.723.0e-02Click!
ARNTchr1_150848538_1508491452140.9016130.684.6e-02Click!
ARNTchr1_150847979_1508482439440.4495060.655.7e-02Click!
ARNTchr1_150849308_1508495061630.9266790.265.0e-01Click!
ARNTchr1_150825207_150825358237730.1068390.206.0e-01Click!

Activity of the ARNT motif across conditions

Conditions sorted by the z-value of the ARNT motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_131485272_131485551 0.31 GPR148
G protein-coupled receptor 148
1232
0.38
chr11_63933058_63933366 0.29 MACROD1
MACRO domain containing 1
321
0.79
chr5_2750019_2750705 0.29 IRX2
iroquois homeobox 2
1407
0.43
chr5_132759480_132759652 0.29 ENSG00000221287
.
3832
0.29
chr8_144489610_144489841 0.28 RP11-909N17.2

5194
0.11
chr17_79455160_79455369 0.27 ENSG00000266077
.
22871
0.08
chr12_132627869_132628125 0.27 DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
883
0.41
chr12_52607516_52607667 0.26 KRT7
keratin 7
19307
0.1
chr2_74709205_74709356 0.26 CCDC142
coiled-coil domain containing 142
843
0.25
chr15_102156310_102156522 0.24 ENSG00000252614
.
32099
0.15
chr16_2835054_2835205 0.24 PRSS33
protease, serine, 33
1477
0.19
chr9_101983648_101983918 0.24 ALG2
ALG2, alpha-1,3/1,6-mannosyltransferase
454
0.53
chr6_6724392_6724959 0.24 LY86-AS1
LY86 antisense RNA 1
101671
0.08
chr7_1452438_1452589 0.24 MICALL2
MICAL-like 2
46449
0.12
chr16_54971124_54971492 0.23 IRX5
iroquois homeobox 5
5324
0.35
chrX_54385157_54385424 0.23 WNK3
WNK lysine deficient protein kinase 3
215
0.95
chr16_412126_412277 0.23 MRPL28
mitochondrial ribosomal protein L28
7602
0.1
chr11_114168914_114169158 0.23 NNMT
nicotinamide N-methyltransferase
163
0.96
chr22_21983451_21983676 0.23 YDJC
YdjC homolog (bacterial)
762
0.44
chr19_42388528_42389094 0.23 ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
296
0.84
chr2_219263865_219264034 0.23 RP11-378A13.2

7
0.89
chr14_103523327_103523546 0.22 CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
363
0.87
chr3_45634856_45635007 0.22 LIMD1
LIM domains containing 1
885
0.47
chr2_242157667_242157840 0.22 ANO7
anoctamin 7
723
0.57
chr16_1582253_1582404 0.22 IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
1167
0.25
chr11_126286106_126286257 0.21 ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
9504
0.19
chr12_132629348_132629597 0.21 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
163
0.84
chr2_230578195_230578473 0.21 DNER
delta/notch-like EGF repeat containing
940
0.67
chr10_6763782_6764322 0.21 PRKCQ
protein kinase C, theta
141789
0.05
chr20_56284469_56284624 0.21 PMEPA1
prostate transmembrane protein, androgen induced 1
270
0.94
chr5_37837239_37837572 0.21 GDNF
glial cell derived neurotrophic factor
1476
0.5
chr6_42981926_42982205 0.20 KLHDC3
kelch domain containing 3
78
0.79
chr9_139971940_139972113 0.20 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
73
0.9
chr14_62164707_62164858 0.20 HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
442
0.87
chr19_58740200_58740521 0.20 ZNF544
zinc finger protein 544
19
0.96
chr19_11307291_11307483 0.20 KANK2
KN motif and ankyrin repeat domains 2
810
0.47
chrX_48693575_48693797 0.20 PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
349
0.78
chr19_872356_872546 0.20 CFD
complement factor D (adipsin)
12761
0.07
chr5_95295455_95295746 0.20 ELL2
elongation factor, RNA polymerase II, 2
1952
0.29
chr4_3295822_3296014 0.19 RGS12
regulator of G-protein signaling 12
14844
0.22
chr9_131937344_131937495 0.19 RP11-247A12.8

667
0.53
chr7_150671435_150671586 0.19 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
3504
0.16
chr19_50393499_50393760 0.19 ENSG00000263462
.
2197
0.1
chr1_7741272_7741423 0.19 CAMTA1
calmodulin binding transcription activator 1
55121
0.13
chr19_55591836_55592067 0.19 EPS8L1
EPS8-like 1
191
0.89
chr8_1299707_1299858 0.19 DLGAP2
discs, large (Drosophila) homolog-associated protein 2
149750
0.05
chr20_37063439_37063660 0.19 ENSG00000200354
.
908
0.36
chr5_172754839_172755250 0.19 STC2
stanniocalcin 2
12
0.98
chrX_40440226_40440477 0.19 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
88
0.98
chr2_29117613_29117819 0.18 WDR43
WD repeat domain 43
207
0.9
chr1_8938987_8939186 0.18 ENO1-AS1
ENO1 antisense RNA 1
192
0.51
chr17_76182928_76183355 0.18 TK1
thymidine kinase 1, soluble
3
0.77
chr2_132249108_132249321 0.18 ENSG00000265575
.
405
0.67
chr20_983106_983257 0.18 RSPO4
R-spondin 4
274
0.94
chr5_37839189_37839372 0.18 GDNF
glial cell derived neurotrophic factor
502
0.85
chr16_88218272_88218475 0.18 BANP
BTG3 associated nuclear protein
214749
0.02
chr17_81060853_81061004 0.18 METRNL
meteorin, glial cell differentiation regulator-like
8934
0.25
chr13_44947783_44948184 0.18 SERP2
stress-associated endoplasmic reticulum protein family member 2
5
0.99
chr18_28681249_28681463 0.17 RP11-408H20.2

195
0.81
chr1_1015177_1015464 0.17 RNF223
ring finger protein 223
5633
0.1
chr17_30184995_30185438 0.17 COPRS
coordinator of PRMT5, differentiation stimulator
734
0.68
chr11_122526658_122526900 0.17 UBASH3B
ubiquitin associated and SH3 domain containing B
396
0.89
chr10_30657102_30657253 0.17 ENSG00000239625
.
1930
0.26
chr2_220110281_220110459 0.17 STK16
serine/threonine kinase 16
165
0.47
chr19_36347189_36347340 0.17 KIRREL2
kin of IRRE like 2 (Drosophila)
225
0.84
chr5_176544101_176544259 0.17 NSD1
nuclear receptor binding SET domain protein 1
15900
0.17
chr1_17766506_17766801 0.17 RCC2
regulator of chromosome condensation 2
433
0.8
chr5_76325920_76326128 0.17 AGGF1
angiogenic factor with G patch and FHA domains 1
186
0.94
chr11_75945794_75945986 0.17 WNT11
wingless-type MMTV integration site family, member 11
24110
0.18
chr3_128369380_128369595 0.17 RPN1
ribophorin I
205
0.95
chr8_145024226_145024570 0.17 PLEC
plectin
646
0.55
chr11_16947220_16947414 0.17 PLEKHA7
pleckstrin homology domain containing, family A member 7
44412
0.12
chr9_127420716_127421619 0.17 MIR181A2HG
MIR181A2 host gene (non-protein coding)
421
0.82
chr15_93352280_93352431 0.17 CTD-2313J17.1

558
0.5
chr19_45348968_45349138 0.17 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
379
0.77
chr22_40390537_40390747 0.17 FAM83F
family with sequence similarity 83, member F
311
0.89
chr17_78801074_78801247 0.17 RP11-28G8.1

21728
0.2
chr11_64623678_64623829 0.17 CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
11712
0.1
chr6_144536832_144537278 0.17 STX11
syntaxin 11
65392
0.12
chr14_104185073_104185224 0.17 ZFYVE21
zinc finger, FYVE domain containing 21
3003
0.11
chr10_112113035_112113246 0.17 SMNDC1
survival motor neuron domain containing 1
48431
0.14
chr16_685986_686262 0.16 C16orf13
chromosome 16 open reading frame 13
111
0.88
chr20_49212701_49212852 0.16 ENSG00000208018
.
10453
0.12
chr11_65685287_65685762 0.16 C11orf68
chromosome 11 open reading frame 68
307
0.73
chr7_561168_561519 0.16 PDGFA
platelet-derived growth factor alpha polypeptide
1410
0.43
chr12_123459866_123460094 0.16 OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
194
0.53
chr1_19535913_19536146 0.16 UBR4
ubiquitin protein ligase E3 component n-recognin 4
717
0.45
chr17_40719217_40719503 0.16 MLX
MLX, MAX dimerization protein
268
0.79
chr17_41669450_41669625 0.16 ETV4
ets variant 4
12549
0.16
chr9_138800141_138800427 0.16 RP11-432J22.2

626
0.62
chr1_1015485_1015798 0.16 RNF223
ring finger protein 223
5954
0.1
chr16_103384_103581 0.16 POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
146
0.71
chr5_177027725_177027944 0.16 B4GALT7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
603
0.63
chr7_28726429_28726958 0.16 CREB5
cAMP responsive element binding protein 5
1095
0.68
chr13_45151017_45151362 0.16 TSC22D1
TSC22 domain family, member 1
94
0.98
chr12_106751582_106751765 0.16 POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
187
0.96
chr2_102003302_102003471 0.16 CREG2
cellular repressor of E1A-stimulated genes 2
671
0.76
chr8_145114785_145114936 0.16 OPLAH
5-oxoprolinase (ATP-hydrolysing)
724
0.42
chr11_133907029_133907299 0.16 JAM3
junctional adhesion molecule 3
31656
0.18
chr17_80188177_80188492 0.16 SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
1365
0.28
chr10_5708404_5708555 0.16 ASB13
ankyrin repeat and SOCS box containing 13
62
0.97
chr1_6844402_6844649 0.16 RP11-312B8.1

378
0.72
chr9_22005843_22006115 0.15 CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
2973
0.2
chr17_44271027_44271377 0.15 KANSL1
KAT8 regulatory NSL complex subunit 1
43
0.71
chr17_55162544_55162695 0.15 AKAP1
A kinase (PRKA) anchor protein 1
66
0.97
chr2_119981485_119981702 0.15 STEAP3
STEAP family member 3, metalloreductase
164
0.96
chr8_145598687_145598886 0.15 ADCK5
aarF domain containing kinase 5
1036
0.26
chr11_59328517_59328703 0.15 ENSG00000252893
.
2337
0.21
chr10_119303143_119303333 0.15 EMX2
empty spiracles homeobox 2
729
0.61
chr7_29724672_29724931 0.15 ENSG00000212024
.
4357
0.26
chr8_131220802_131220953 0.15 ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
27769
0.21
chr7_55087325_55087551 0.15 EGFR
epidermal growth factor receptor
627
0.83
chr14_105634190_105634406 0.15 JAG2
jagged 2
863
0.58
chr3_47050375_47050596 0.15 NBEAL2
neurobeachin-like 2
3714
0.23
chr3_52567337_52567575 0.15 NT5DC2
5'-nucleotidase domain containing 2
91
0.94
chr6_5261297_5261469 0.15 FARS2
phenylalanyl-tRNA synthetase 2, mitochondrial
106
0.65
chr9_100954695_100954863 0.15 CORO2A
coronin, actin binding protein, 2A
143
0.97
chr14_95968879_95969030 0.15 RP11-1070N10.3
Uncharacterized protein
13519
0.15
chr11_3043840_3044115 0.15 CARS-AS1
CARS antisense RNA 1
6647
0.13
chr12_122016646_122016834 0.15 KDM2B
lysine (K)-specific demethylase 2B
809
0.64
chr1_22262052_22262277 0.15 HSPG2
heparan sulfate proteoglycan 2
1626
0.3
chr5_178692264_178692415 0.15 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
80092
0.1
chr16_1031099_1031287 0.15 AC009041.2

59
0.53
chr18_33709836_33710625 0.15 ELP2
elongator acetyltransferase complex subunit 2
343
0.76
chr5_77657075_77657365 0.15 SCAMP1
secretory carrier membrane protein 1
881
0.65
chr4_66534785_66535387 0.15 EPHA5
EPH receptor A5
567
0.87
chr8_13124541_13124692 0.15 DLC1
deleted in liver cancer 1
9439
0.27
chr17_76920259_76920615 0.15 TIMP2
TIMP metallopeptidase inhibitor 2
1032
0.46
chr7_120590823_120591031 0.15 ING3
inhibitor of growth family, member 3
78
0.98
chr3_25825194_25825429 0.15 NGLY1
N-glycanase 1
269
0.8
chr16_21312757_21313165 0.15 CRYM
crystallin, mu
1411
0.46
chr1_170630467_170630618 0.15 PRRX1
paired related homeobox 1
1733
0.5
chr19_42756951_42757222 0.15 ERF
Ets2 repressor factor
965
0.32
chr16_56660383_56660534 0.15 MT1E
metallothionein 1E
748
0.38
chr7_120970338_120970562 0.15 WNT16
wingless-type MMTV integration site family, member 16
1393
0.55
chr1_59762514_59762724 0.15 FGGY
FGGY carbohydrate kinase domain containing
34
0.99
chr3_133613529_133613925 0.15 RAB6B
RAB6B, member RAS oncogene family
164
0.96
chr5_180258685_180258971 0.14 MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
16248
0.15
chr16_3766918_3767450 0.14 TRAP1
TNF receptor-associated protein 1
330
0.88
chr12_4016019_4016170 0.14 RP11-664D1.1

1708
0.45
chr5_150474677_150474941 0.14 TNIP1
TNFAIP3 interacting protein 1
1671
0.38
chr1_228464183_228464334 0.14 RP5-1139B12.3

491
0.48
chr5_88179408_88179656 0.14 MEF2C
myocyte enhancer factor 2C
230
0.58
chr1_46154130_46154324 0.14 TMEM69
transmembrane protein 69
1341
0.32
chr19_13105787_13106145 0.14 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
456
0.65
chr16_58534463_58534728 0.14 NDRG4
NDRG family member 4
545
0.68
chr7_42896384_42896593 0.14 C7orf25
chromosome 7 open reading frame 25
55021
0.14
chr16_86029527_86029733 0.14 IRF8
interferon regulatory factor 8
81711
0.1
chr7_26191850_26192061 0.14 NFE2L3
nuclear factor, erythroid 2-like 3
95
0.97
chr19_46388726_46388877 0.14 IRF2BP1
interferon regulatory factor 2 binding protein 1
575
0.6
chr10_3713222_3713373 0.14 RP11-184A2.3

79962
0.1
chr15_63664855_63665177 0.14 CA12
carbonic anhydrase XII
9018
0.26
chr16_50279487_50279793 0.14 ADCY7
adenylate cyclase 7
408
0.87
chr9_135116864_135117052 0.14 ENSG00000221105
.
26696
0.2
chr12_110841210_110841465 0.14 ANAPC7
anaphase promoting complex subunit 7
198
0.93
chr10_135072065_135072216 0.14 MIR202HG
MIR202 host gene (non-protein coding)
10745
0.1
chr13_100622367_100622591 0.14 ZIC5
Zic family member 5
1684
0.37
chr2_75787048_75787447 0.14 EVA1A
eva-1 homolog A (C. elegans)
792
0.61
chr17_77810510_77810661 0.14 CBX4
chromobox homolog 4
1095
0.45
chr17_47492474_47492819 0.14 PHB
prohibitin
400
0.74
chr5_112823740_112823994 0.14 MCC
mutated in colorectal cancers
660
0.69
chr19_53561526_53561765 0.14 ERVV-2
endogenous retrovirus group V, member 2
13654
0.13
chr2_218875419_218875830 0.14 TNS1
tensin 1
7906
0.19
chr4_151504224_151504433 0.14 MAB21L2
mab-21-like 2 (C. elegans)
1251
0.5
chr18_33877306_33877457 0.14 FHOD3
formin homology 2 domain containing 3
296
0.94
chr18_29672721_29672919 0.14 RNF138
ring finger protein 138, E3 ubiquitin protein ligase
155
0.85
chr9_117880223_117880437 0.14 TNC
tenascin C
148
0.97
chr12_85305306_85305778 0.14 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
261
0.96
chr22_31318038_31318328 0.14 MORC2-AS1
MORC2 antisense RNA 1
112
0.96
chr20_36012996_36013224 0.14 SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
557
0.83
chr3_64670816_64671530 0.14 ADAMTS9-AS2
ADAMTS9 antisense RNA 2
369
0.87
chr6_133134294_133134903 0.14 RPS12
ribosomal protein S12
982
0.36
chr13_47216013_47216251 0.14 LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
37839
0.21
chr7_80548112_80548336 0.14 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
275
0.96
chr4_103749429_103750293 0.13 UBE2D3
ubiquitin-conjugating enzyme E2D 3
545
0.48
chr8_6692471_6692922 0.13 DEFB1
defensin, beta 1
42848
0.14
chr11_280052_280224 0.13 NLRP6
NLR family, pyrin domain containing 6
1568
0.17
chr19_8478096_8478249 0.13 MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
2
0.95
chr11_66725676_66725918 0.13 PC
pyruvate carboxylase
50
0.96
chr5_171614762_171615007 0.13 STK10
serine/threonine kinase 10
506
0.79
chr15_43622511_43622752 0.13 LCMT2
leucine carboxyl methyltransferase 2
142
0.62
chr17_42061018_42061294 0.13 PYY
peptide YY
20681
0.09
chr9_98075387_98075786 0.13 FANCC
Fanconi anemia, complementation group C
3590
0.32
chr19_49575534_49575685 0.13 KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
589
0.44
chr2_14773218_14773477 0.13 FAM84A
family with sequence similarity 84, member A
523
0.79
chr1_1476103_1476407 0.13 TMEM240
transmembrane protein 240
422
0.72
chr19_48901834_48902054 0.13 GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
3812
0.13
chr22_42977224_42977384 0.13 RRP7B
ribosomal RNA processing 7 homolog B (S. cerevisiae)
703
0.51
chr2_176866202_176866353 0.13 KIAA1715
KIAA1715
714
0.68
chr11_65203008_65203266 0.13 ENSG00000245532
.
8792
0.12
chr19_4064959_4065214 0.13 ZBTB7A
zinc finger and BTB domain containing 7A
644
0.56
chr17_49243327_49243635 0.13 NME1-NME2
NME1-NME2 readthrough
158
0.94
chr17_77962275_77962426 0.13 CTD-2529O21.1

4290
0.18
chr6_106577027_106577713 0.13 RP1-134E15.3

29355
0.19
chr7_767169_767320 0.13 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
43
0.84
chr8_66556267_66556716 0.13 MTFR1
mitochondrial fission regulator 1
483
0.82
chr7_97841044_97841241 0.13 BHLHA15
basic helix-loop-helix family, member a15
403
0.86
chr1_110167573_110167724 0.13 AMPD2
adenosine monophosphate deaminase 2
572
0.56
chr2_43037752_43038106 0.13 HAAO
3-hydroxyanthranilate 3,4-dioxygenase
18197
0.23
chr1_78957034_78957258 0.13 PTGFR
prostaglandin F receptor (FP)
389
0.91

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ARNT

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060676 ureteric bud formation(GO:0060676)
0.1 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.1 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.2 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.5 GO:0036294 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0048342 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:0009218 pyrimidine ribonucleotide metabolic process(GO:0009218)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0032351 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.4 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0072189 ureter development(GO:0072189) kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.2 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.0 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0042559 folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.1 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0003170 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.0 GO:0061339 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.3 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.1 GO:0042772 DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0060487 lung epithelial cell differentiation(GO:0060487)
0.0 0.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.0 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.0 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.0 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0032292 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.0 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.0 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:1901222 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0052173 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0 0.0 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0090232 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.0 GO:0045620 negative regulation of lymphocyte differentiation(GO:0045620)
0.0 0.1 GO:0060767 epithelial cell proliferation involved in prostate gland development(GO:0060767)
0.0 0.2 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.0 GO:0010939 regulation of necrotic cell death(GO:0010939)
0.0 0.0 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.0 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.0 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.0 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.0 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0009268 response to pH(GO:0009268)
0.0 0.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.9 GO:0006364 rRNA processing(GO:0006364)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.0 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0050684 regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0 0.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.6 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.4 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.0 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0016715 dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0010181 FMN binding(GO:0010181)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.0 GO:0000739 obsolete DNA strand annealing activity(GO:0000739) ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.0 REACTOME S PHASE Genes involved in S Phase
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity