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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for ARNT

Z-value: 1.25

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Transcription factors associated with ARNT

Gene Symbol	Gene ID	Gene Info
ARNT Ensembl NCBI GeneCards UniProt	ENSG00000143437.16	aryl hydrocarbon receptor nuclear translocator

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_150848247_150848479	ARNT	692	0.578414	0.72	3.0e-02	Click!
chr1_150848538_150849145	ARNT	214	0.901613	0.68	4.6e-02	Click!
chr1_150847979_150848243	ARNT	944	0.449506	0.65	5.7e-02	Click!
chr1_150849308_150849506	ARNT	163	0.926679	0.26	5.0e-01	Click!
chr1_150825207_150825358	ARNT	23773	0.106839	0.20	6.0e-01	Click!

Activity of the ARNT motif across conditions

Conditions sorted by the z-value of the ARNT motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_131485272_131485551	0.31	GPR148	G protein-coupled receptor 148	1232	0.38
chr11_63933058_63933366	0.29	MACROD1	MACRO domain containing 1	321	0.79
chr5_2750019_2750705	0.29	IRX2	iroquois homeobox 2	1407	0.43
chr5_132759480_132759652	0.29	ENSG00000221287	.	3832	0.29
chr8_144489610_144489841	0.28	RP11-909N17.2		5194	0.11
chr17_79455160_79455369	0.27	ENSG00000266077	.	22871	0.08
chr12_132627869_132628125	0.27	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	883	0.41
chr12_52607516_52607667	0.26	KRT7	keratin 7	19307	0.1
chr2_74709205_74709356	0.26	CCDC142	coiled-coil domain containing 142	843	0.25
chr15_102156310_102156522	0.24	ENSG00000252614	.	32099	0.15
chr16_2835054_2835205	0.24	PRSS33	protease, serine, 33	1477	0.19
chr9_101983648_101983918	0.24	ALG2	ALG2, alpha-1,3/1,6-mannosyltransferase	454	0.53
chr6_6724392_6724959	0.24	LY86-AS1	LY86 antisense RNA 1	101671	0.08
chr7_1452438_1452589	0.24	MICALL2	MICAL-like 2	46449	0.12
chr16_54971124_54971492	0.23	IRX5	iroquois homeobox 5	5324	0.35
chrX_54385157_54385424	0.23	WNK3	WNK lysine deficient protein kinase 3	215	0.95
chr16_412126_412277	0.23	MRPL28	mitochondrial ribosomal protein L28	7602	0.1
chr11_114168914_114169158	0.23	NNMT	nicotinamide N-methyltransferase	163	0.96
chr22_21983451_21983676	0.23	YDJC	YdjC homolog (bacterial)	762	0.44
chr19_42388528_42389094	0.23	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	296	0.84
chr2_219263865_219264034	0.23	RP11-378A13.2		7	0.89
chr14_103523327_103523546	0.22	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	363	0.87
chr3_45634856_45635007	0.22	LIMD1	LIM domains containing 1	885	0.47
chr2_242157667_242157840	0.22	ANO7	anoctamin 7	723	0.57
chr16_1582253_1582404	0.22	IFT140	intraflagellar transport 140 homolog (Chlamydomonas)	1167	0.25
chr11_126286106_126286257	0.21	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	9504	0.19
chr12_132629348_132629597	0.21	NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)	163	0.84
chr2_230578195_230578473	0.21	DNER	delta/notch-like EGF repeat containing	940	0.67
chr10_6763782_6764322	0.21	PRKCQ	protein kinase C, theta	141789	0.05
chr20_56284469_56284624	0.21	PMEPA1	prostate transmembrane protein, androgen induced 1	270	0.94
chr5_37837239_37837572	0.21	GDNF	glial cell derived neurotrophic factor	1476	0.5
chr6_42981926_42982205	0.20	KLHDC3	kelch domain containing 3	78	0.79
chr9_139971940_139972113	0.20	UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	73	0.9
chr14_62164707_62164858	0.20	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	442	0.87
chr19_58740200_58740521	0.20	ZNF544	zinc finger protein 544	19	0.96
chr19_11307291_11307483	0.20	KANK2	KN motif and ankyrin repeat domains 2	810	0.47
chrX_48693575_48693797	0.20	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor	349	0.78
chr19_872356_872546	0.20	CFD	complement factor D (adipsin)	12761	0.07
chr5_95295455_95295746	0.20	ELL2	elongation factor, RNA polymerase II, 2	1952	0.29
chr4_3295822_3296014	0.19	RGS12	regulator of G-protein signaling 12	14844	0.22
chr9_131937344_131937495	0.19	RP11-247A12.8		667	0.53
chr7_150671435_150671586	0.19	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	3504	0.16
chr19_50393499_50393760	0.19	ENSG00000263462	.	2197	0.1
chr1_7741272_7741423	0.19	CAMTA1	calmodulin binding transcription activator 1	55121	0.13
chr19_55591836_55592067	0.19	EPS8L1	EPS8-like 1	191	0.89
chr8_1299707_1299858	0.19	DLGAP2	discs, large (Drosophila) homolog-associated protein 2	149750	0.05
chr20_37063439_37063660	0.19	ENSG00000200354	.	908	0.36
chr5_172754839_172755250	0.19	STC2	stanniocalcin 2	12	0.98
chrX_40440226_40440477	0.19	ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2	88	0.98
chr2_29117613_29117819	0.18	WDR43	WD repeat domain 43	207	0.9
chr1_8938987_8939186	0.18	ENO1-AS1	ENO1 antisense RNA 1	192	0.51
chr17_76182928_76183355	0.18	TK1	thymidine kinase 1, soluble	3	0.77
chr2_132249108_132249321	0.18	ENSG00000265575	.	405	0.67
chr20_983106_983257	0.18	RSPO4	R-spondin 4	274	0.94
chr5_37839189_37839372	0.18	GDNF	glial cell derived neurotrophic factor	502	0.85
chr16_88218272_88218475	0.18	BANP	BTG3 associated nuclear protein	214749	0.02
chr17_81060853_81061004	0.18	METRNL	meteorin, glial cell differentiation regulator-like	8934	0.25
chr13_44947783_44948184	0.18	SERP2	stress-associated endoplasmic reticulum protein family member 2	5	0.99
chr18_28681249_28681463	0.17	RP11-408H20.2		195	0.81
chr1_1015177_1015464	0.17	RNF223	ring finger protein 223	5633	0.1
chr17_30184995_30185438	0.17	COPRS	coordinator of PRMT5, differentiation stimulator	734	0.68
chr11_122526658_122526900	0.17	UBASH3B	ubiquitin associated and SH3 domain containing B	396	0.89
chr10_30657102_30657253	0.17	ENSG00000239625	.	1930	0.26
chr2_220110281_220110459	0.17	STK16	serine/threonine kinase 16	165	0.47
chr19_36347189_36347340	0.17	KIRREL2	kin of IRRE like 2 (Drosophila)	225	0.84
chr5_176544101_176544259	0.17	NSD1	nuclear receptor binding SET domain protein 1	15900	0.17
chr1_17766506_17766801	0.17	RCC2	regulator of chromosome condensation 2	433	0.8
chr5_76325920_76326128	0.17	AGGF1	angiogenic factor with G patch and FHA domains 1	186	0.94
chr11_75945794_75945986	0.17	WNT11	wingless-type MMTV integration site family, member 11	24110	0.18
chr3_128369380_128369595	0.17	RPN1	ribophorin I	205	0.95
chr8_145024226_145024570	0.17	PLEC	plectin	646	0.55
chr11_16947220_16947414	0.17	PLEKHA7	pleckstrin homology domain containing, family A member 7	44412	0.12
chr9_127420716_127421619	0.17	MIR181A2HG	MIR181A2 host gene (non-protein coding)	421	0.82
chr15_93352280_93352431	0.17	CTD-2313J17.1		558	0.5
chr19_45348968_45349138	0.17	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	379	0.77
chr22_40390537_40390747	0.17	FAM83F	family with sequence similarity 83, member F	311	0.89
chr17_78801074_78801247	0.17	RP11-28G8.1		21728	0.2
chr11_64623678_64623829	0.17	CDC42BPG	CDC42 binding protein kinase gamma (DMPK-like)	11712	0.1
chr6_144536832_144537278	0.17	STX11	syntaxin 11	65392	0.12
chr14_104185073_104185224	0.17	ZFYVE21	zinc finger, FYVE domain containing 21	3003	0.11
chr10_112113035_112113246	0.17	SMNDC1	survival motor neuron domain containing 1	48431	0.14
chr16_685986_686262	0.16	C16orf13	chromosome 16 open reading frame 13	111	0.88
chr20_49212701_49212852	0.16	ENSG00000208018	.	10453	0.12
chr11_65685287_65685762	0.16	C11orf68	chromosome 11 open reading frame 68	307	0.73
chr7_561168_561519	0.16	PDGFA	platelet-derived growth factor alpha polypeptide	1410	0.43
chr12_123459866_123460094	0.16	OGFOD2	2-oxoglutarate and iron-dependent oxygenase domain containing 2	194	0.53
chr1_19535913_19536146	0.16	UBR4	ubiquitin protein ligase E3 component n-recognin 4	717	0.45
chr17_40719217_40719503	0.16	MLX	MLX, MAX dimerization protein	268	0.79
chr17_41669450_41669625	0.16	ETV4	ets variant 4	12549	0.16
chr9_138800141_138800427	0.16	RP11-432J22.2		626	0.62
chr1_1015485_1015798	0.16	RNF223	ring finger protein 223	5954	0.1
chr16_103384_103581	0.16	POLR3K	polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa	146	0.71
chr5_177027725_177027944	0.16	B4GALT7	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7	603	0.63
chr7_28726429_28726958	0.16	CREB5	cAMP responsive element binding protein 5	1095	0.68
chr13_45151017_45151362	0.16	TSC22D1	TSC22 domain family, member 1	94	0.98
chr12_106751582_106751765	0.16	POLR3B	polymerase (RNA) III (DNA directed) polypeptide B	187	0.96
chr2_102003302_102003471	0.16	CREG2	cellular repressor of E1A-stimulated genes 2	671	0.76
chr8_145114785_145114936	0.16	OPLAH	5-oxoprolinase (ATP-hydrolysing)	724	0.42
chr11_133907029_133907299	0.16	JAM3	junctional adhesion molecule 3	31656	0.18
chr17_80188177_80188492	0.16	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3	1365	0.28
chr10_5708404_5708555	0.16	ASB13	ankyrin repeat and SOCS box containing 13	62	0.97
chr1_6844402_6844649	0.16	RP11-312B8.1		378	0.72
chr9_22005843_22006115	0.15	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	2973	0.2
chr17_44271027_44271377	0.15	KANSL1	KAT8 regulatory NSL complex subunit 1	43	0.71
chr17_55162544_55162695	0.15	AKAP1	A kinase (PRKA) anchor protein 1	66	0.97
chr2_119981485_119981702	0.15	STEAP3	STEAP family member 3, metalloreductase	164	0.96
chr8_145598687_145598886	0.15	ADCK5	aarF domain containing kinase 5	1036	0.26
chr11_59328517_59328703	0.15	ENSG00000252893	.	2337	0.21
chr10_119303143_119303333	0.15	EMX2	empty spiracles homeobox 2	729	0.61
chr7_29724672_29724931	0.15	ENSG00000212024	.	4357	0.26
chr8_131220802_131220953	0.15	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	27769	0.21
chr7_55087325_55087551	0.15	EGFR	epidermal growth factor receptor	627	0.83
chr14_105634190_105634406	0.15	JAG2	jagged 2	863	0.58
chr3_47050375_47050596	0.15	NBEAL2	neurobeachin-like 2	3714	0.23
chr3_52567337_52567575	0.15	NT5DC2	5'-nucleotidase domain containing 2	91	0.94
chr6_5261297_5261469	0.15	FARS2	phenylalanyl-tRNA synthetase 2, mitochondrial	106	0.65
chr9_100954695_100954863	0.15	CORO2A	coronin, actin binding protein, 2A	143	0.97
chr14_95968879_95969030	0.15	RP11-1070N10.3	Uncharacterized protein	13519	0.15
chr11_3043840_3044115	0.15	CARS-AS1	CARS antisense RNA 1	6647	0.13
chr12_122016646_122016834	0.15	KDM2B	lysine (K)-specific demethylase 2B	809	0.64
chr1_22262052_22262277	0.15	HSPG2	heparan sulfate proteoglycan 2	1626	0.3
chr5_178692264_178692415	0.15	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	80092	0.1
chr16_1031099_1031287	0.15	AC009041.2		59	0.53
chr18_33709836_33710625	0.15	ELP2	elongator acetyltransferase complex subunit 2	343	0.76
chr5_77657075_77657365	0.15	SCAMP1	secretory carrier membrane protein 1	881	0.65
chr4_66534785_66535387	0.15	EPHA5	EPH receptor A5	567	0.87
chr8_13124541_13124692	0.15	DLC1	deleted in liver cancer 1	9439	0.27
chr17_76920259_76920615	0.15	TIMP2	TIMP metallopeptidase inhibitor 2	1032	0.46
chr7_120590823_120591031	0.15	ING3	inhibitor of growth family, member 3	78	0.98
chr3_25825194_25825429	0.15	NGLY1	N-glycanase 1	269	0.8
chr16_21312757_21313165	0.15	CRYM	crystallin, mu	1411	0.46
chr1_170630467_170630618	0.15	PRRX1	paired related homeobox 1	1733	0.5
chr19_42756951_42757222	0.15	ERF	Ets2 repressor factor	965	0.32
chr16_56660383_56660534	0.15	MT1E	metallothionein 1E	748	0.38
chr7_120970338_120970562	0.15	WNT16	wingless-type MMTV integration site family, member 16	1393	0.55
chr1_59762514_59762724	0.15	FGGY	FGGY carbohydrate kinase domain containing	34	0.99
chr3_133613529_133613925	0.15	RAB6B	RAB6B, member RAS oncogene family	164	0.96
chr5_180258685_180258971	0.14	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	16248	0.15
chr16_3766918_3767450	0.14	TRAP1	TNF receptor-associated protein 1	330	0.88
chr12_4016019_4016170	0.14	RP11-664D1.1		1708	0.45
chr5_150474677_150474941	0.14	TNIP1	TNFAIP3 interacting protein 1	1671	0.38
chr1_228464183_228464334	0.14	RP5-1139B12.3		491	0.48
chr5_88179408_88179656	0.14	MEF2C	myocyte enhancer factor 2C	230	0.58
chr1_46154130_46154324	0.14	TMEM69	transmembrane protein 69	1341	0.32
chr19_13105787_13106145	0.14	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	456	0.65
chr16_58534463_58534728	0.14	NDRG4	NDRG family member 4	545	0.68
chr7_42896384_42896593	0.14	C7orf25	chromosome 7 open reading frame 25	55021	0.14
chr16_86029527_86029733	0.14	IRF8	interferon regulatory factor 8	81711	0.1
chr7_26191850_26192061	0.14	NFE2L3	nuclear factor, erythroid 2-like 3	95	0.97
chr19_46388726_46388877	0.14	IRF2BP1	interferon regulatory factor 2 binding protein 1	575	0.6
chr10_3713222_3713373	0.14	RP11-184A2.3		79962	0.1
chr15_63664855_63665177	0.14	CA12	carbonic anhydrase XII	9018	0.26
chr16_50279487_50279793	0.14	ADCY7	adenylate cyclase 7	408	0.87
chr9_135116864_135117052	0.14	ENSG00000221105	.	26696	0.2
chr12_110841210_110841465	0.14	ANAPC7	anaphase promoting complex subunit 7	198	0.93
chr10_135072065_135072216	0.14	MIR202HG	MIR202 host gene (non-protein coding)	10745	0.1
chr13_100622367_100622591	0.14	ZIC5	Zic family member 5	1684	0.37
chr2_75787048_75787447	0.14	EVA1A	eva-1 homolog A (C. elegans)	792	0.61
chr17_77810510_77810661	0.14	CBX4	chromobox homolog 4	1095	0.45
chr17_47492474_47492819	0.14	PHB	prohibitin	400	0.74
chr5_112823740_112823994	0.14	MCC	mutated in colorectal cancers	660	0.69
chr19_53561526_53561765	0.14	ERVV-2	endogenous retrovirus group V, member 2	13654	0.13
chr2_218875419_218875830	0.14	TNS1	tensin 1	7906	0.19
chr4_151504224_151504433	0.14	MAB21L2	mab-21-like 2 (C. elegans)	1251	0.5
chr18_33877306_33877457	0.14	FHOD3	formin homology 2 domain containing 3	296	0.94
chr18_29672721_29672919	0.14	RNF138	ring finger protein 138, E3 ubiquitin protein ligase	155	0.85
chr9_117880223_117880437	0.14	TNC	tenascin C	148	0.97
chr12_85305306_85305778	0.14	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15	261	0.96
chr22_31318038_31318328	0.14	MORC2-AS1	MORC2 antisense RNA 1	112	0.96
chr20_36012996_36013224	0.14	SRC	v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog	557	0.83
chr3_64670816_64671530	0.14	ADAMTS9-AS2	ADAMTS9 antisense RNA 2	369	0.87
chr6_133134294_133134903	0.14	RPS12	ribosomal protein S12	982	0.36
chr13_47216013_47216251	0.14	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	37839	0.21
chr7_80548112_80548336	0.14	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	275	0.96
chr4_103749429_103750293	0.13	UBE2D3	ubiquitin-conjugating enzyme E2D 3	545	0.48
chr8_6692471_6692922	0.13	DEFB1	defensin, beta 1	42848	0.14
chr11_280052_280224	0.13	NLRP6	NLR family, pyrin domain containing 6	1568	0.17
chr19_8478096_8478249	0.13	MARCH2	membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase	2	0.95
chr11_66725676_66725918	0.13	PC	pyruvate carboxylase	50	0.96
chr5_171614762_171615007	0.13	STK10	serine/threonine kinase 10	506	0.79
chr15_43622511_43622752	0.13	LCMT2	leucine carboxyl methyltransferase 2	142	0.62
chr17_42061018_42061294	0.13	PYY	peptide YY	20681	0.09
chr9_98075387_98075786	0.13	FANCC	Fanconi anemia, complementation group C	3590	0.32
chr19_49575534_49575685	0.13	KCNA7	potassium voltage-gated channel, shaker-related subfamily, member 7	589	0.44
chr2_14773218_14773477	0.13	FAM84A	family with sequence similarity 84, member A	523	0.79
chr1_1476103_1476407	0.13	TMEM240	transmembrane protein 240	422	0.72
chr19_48901834_48902054	0.13	GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	3812	0.13
chr22_42977224_42977384	0.13	RRP7B	ribosomal RNA processing 7 homolog B (S. cerevisiae)	703	0.51
chr2_176866202_176866353	0.13	KIAA1715	KIAA1715	714	0.68
chr11_65203008_65203266	0.13	ENSG00000245532	.	8792	0.12
chr19_4064959_4065214	0.13	ZBTB7A	zinc finger and BTB domain containing 7A	644	0.56
chr17_49243327_49243635	0.13	NME1-NME2	NME1-NME2 readthrough	158	0.94
chr17_77962275_77962426	0.13	CTD-2529O21.1		4290	0.18
chr6_106577027_106577713	0.13	RP1-134E15.3		29355	0.19
chr7_767169_767320	0.13	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta	43	0.84
chr8_66556267_66556716	0.13	MTFR1	mitochondrial fission regulator 1	483	0.82
chr7_97841044_97841241	0.13	BHLHA15	basic helix-loop-helix family, member a15	403	0.86
chr1_110167573_110167724	0.13	AMPD2	adenosine monophosphate deaminase 2	572	0.56
chr2_43037752_43038106	0.13	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	18197	0.23
chr1_78957034_78957258	0.13	PTGFR	prostaglandin F receptor (FP)	389	0.91

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ARNT

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.1	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1	0.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.2	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.3	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.2	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.2	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.2	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.5	GO:0036294	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.2	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.2	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0048342	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.2	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.1	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.3	GO:0009218	pyrimidine ribonucleotide metabolic process(GO:0009218)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.4	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.0	GO:0072189	ureter development(GO:0072189) kidney smooth muscle tissue development(GO:0072194)
0.0	0.1	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.0	0.2	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.0	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.0	GO:0032429	regulation of phospholipase A2 activity(GO:0032429)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0042559	folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.0	0.1	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0003170	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0002068	glandular epithelial cell development(GO:0002068)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.2	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0061526	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:0046021	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.0	GO:0061339	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) negative regulation of receptor activity(GO:2000272)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.0	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.3	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.1	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.1	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.2	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.4	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.2	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0060487	lung epithelial cell differentiation(GO:0060487)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.0	GO:0090224	regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.0	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.3	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.0	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0032292	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.0	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.0	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.0	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.0	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:1901222	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.2	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0052173	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0	0.0	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.0	GO:0045620	negative regulation of lymphocyte differentiation(GO:0045620)
0.0	0.1	GO:0060767	epithelial cell proliferation involved in prostate gland development(GO:0060767)
0.0	0.2	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.0	0.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.4	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.0	0.0	GO:0010939	regulation of necrotic cell death(GO:0010939)
0.0	0.0	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.0	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.0	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0061647	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.4	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.2	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0001774	microglial cell activation(GO:0001774)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.0	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0009268	response to pH(GO:0009268)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.0	0.1	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.9	GO:0006364	rRNA processing(GO:0006364)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.0	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.0	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0050684	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0	0.0	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.6	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.3	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.4	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.3	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.2	GO:0005844	polysome(GO:0005844)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.0	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.0	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.6	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.1	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.6	GO:0005604	basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.3	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.2	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0016715	dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.0	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.3	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.0	GO:0000739	obsolete DNA strand annealing activity(GO:0000739) ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.2	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.4	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.5	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.3	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	REACTOME S PHASE	Genes involved in S Phase
0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.4	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity

Results for ARNT

Z-value: 1.25

Motif logo

Transcription factors associated with ARNT

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ARNT motif across conditions

Conditions sorted by the z-value of the ARNT motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ARNT

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: