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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for AR_NR3C2

Z-value: 0.87

Motif logo

Transcription factors associated with AR_NR3C2

Gene Symbol	Gene ID	Gene Info
AR Ensembl NCBI GeneCards UniProt	ENSG00000169083.11	AR
NR3C2 Ensembl NCBI GeneCards UniProt	ENSG00000151623.10	NR3C2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
AR	chrX_66766516_66766697	1620	0.570375	-0.65	5.9e-02	Click!
AR	chrX_66952827_66952978	164171	0.040013	0.63	6.8e-02	Click!
AR	chrX_66763846_66764061	512	0.891958	-0.61	7.8e-02	Click!
AR	chrX_67000951_67001203	212346	0.025037	-0.52	1.5e-01	Click!
AR	chrX_66767815_66768085	2964	0.426121	-0.52	1.5e-01	Click!
NR3C2	chr4_149367147_149367363	1405	0.591234	0.24	5.3e-01	Click!
NR3C2	chr4_149363777_149364242	337	0.938175	-0.19	6.2e-01	Click!
NR3C2	chr4_149364707_149365251	871	0.750626	0.15	6.9e-01	Click!
NR3C2	chr4_149368732_149368898	2965	0.401266	-0.14	7.2e-01	Click!
NR3C2	chr4_149363274_149363592	57	0.987392	-0.12	7.5e-01	Click!

Activity of the AR_NR3C2 motif across conditions

Conditions sorted by the z-value of the AR_NR3C2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_118955810_118956058	0.61	B4GALT4	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	3070	0.21
chrX_70760188_70760339	0.57	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase	3399	0.24
chr21_46336780_46336931	0.55	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	2657	0.15
chr1_172715599_172715750	0.54	FASLG	Fas ligand (TNF superfamily, member 6)	87516	0.09
chr1_95316335_95316486	0.49	ENSG00000237416	.	4572	0.23
chr5_148309668_148309819	0.47	RP11-44B19.1		40160	0.16
chr6_11381781_11382025	0.46	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	629	0.82
chr6_35568962_35570321	0.45	ENSG00000212579	.	49954	0.1
chr8_134084504_134084857	0.44	SLA	Src-like-adaptor	12077	0.24
chr16_11794621_11794772	0.43	SNN	stannin	32426	0.12
chr15_40659564_40659826	0.41	RP11-64K12.4		2146	0.13
chr12_113416849_113417235	0.40	OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	697	0.66
chr6_154568354_154568864	0.40	IPCEF1	interaction protein for cytohesin exchange factors 1	53	0.99
chr11_114186668_114186999	0.40	NNMT	nicotinamide N-methyltransferase	17960	0.18
chr17_79031323_79031474	0.40	BAIAP2	BAI1-associated protein 2	17	0.97
chr12_51713121_51713481	0.40	BIN2	bridging integrator 2	4598	0.18
chr1_10857132_10857283	0.40	CASZ1	castor zinc finger 1	500	0.85
chr13_46959234_46959385	0.39	KIAA0226L	KIAA0226-like	2008	0.32
chr15_86077505_86077656	0.39	AKAP13	A kinase (PRKA) anchor protein 13	9691	0.21
chr6_13448559_13448819	0.38	AL583828.1		37726	0.13
chr6_36281244_36281395	0.36	C6orf222	chromosome 6 open reading frame 222	23343	0.15
chr13_111213122_111213273	0.35	RAB20	RAB20, member RAS oncogene family	883	0.64
chr6_42013548_42014157	0.35	CCND3	cyclin D3	2572	0.23
chr19_16256933_16257251	0.34	HSH2D	hematopoietic SH2 domain containing	2546	0.18
chr1_112032205_112032457	0.33	ADORA3	adenosine A3 receptor	47	0.91
chr12_52409491_52409642	0.32	GRASP	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	4599	0.14
chr12_26441132_26441283	0.32	RP11-283G6.5		16354	0.18
chr12_40551802_40551953	0.32	LRRK2	leucine-rich repeat kinase 2	38669	0.17
chr6_25006652_25006894	0.31	ENSG00000244618	.	24737	0.17
chr17_80255361_80255512	0.31	CD7	CD7 molecule	19992	0.09
chr15_63891011_63891162	0.31	FBXL22	F-box and leucine-rich repeat protein 22	1185	0.42
chr1_150540056_150540997	0.30	ENSG00000264508	.	1190	0.22
chr2_99439255_99439699	0.30	ENSG00000238830	.	17722	0.19
chr11_113981757_113982173	0.30	ENSG00000221112	.	24314	0.2
chr12_53985901_53986052	0.30	ATF7	activating transcription factor 7	8829	0.15
chr7_150147431_150147649	0.29	GIMAP8	GTPase, IMAP family member 8	178	0.94
chr15_55547653_55548107	0.29	RAB27A	RAB27A, member RAS oncogene family	6647	0.22
chr4_86953999_86954560	0.29	RP13-514E23.1		19252	0.19
chr6_6916042_6916314	0.28	ENSG00000240936	.	22952	0.26
chr2_109605420_109605703	0.28	EDAR	ectodysplasin A receptor	164	0.97
chr8_120126680_120126831	0.28	RP11-278I4.2		45734	0.15
chr2_37817410_37817581	0.28	AC006369.2		9784	0.26
chr3_73085691_73085907	0.28	ENSG00000238959	.	8840	0.16
chr11_46363477_46363864	0.28	DGKZ	diacylglycerol kinase, zeta	3147	0.2
chrX_118710010_118710161	0.27	UBE2A	ubiquitin-conjugating enzyme E2A	1445	0.35
chrX_53100883_53101580	0.27	TSPYL2	TSPY-like 2	10318	0.18
chr3_81873946_81874241	0.27	GBE1	glucan (1,4-alpha-), branching enzyme 1	62781	0.16
chr1_95018005_95018156	0.27	F3	coagulation factor III (thromboplastin, tissue factor)	10724	0.29
chr11_122655510_122655661	0.26	CRTAM	cytotoxic and regulatory T cell molecule	53623	0.12
chr6_6750463_6750647	0.26	LY86-AS1	LY86 antisense RNA 1	127551	0.05
chr12_106178721_106178872	0.26	NUAK1	NUAK family, SNF1-like kinase, 1	299015	0.01
chr12_728674_728825	0.26	NINJ2	ninjurin 2	9165	0.14
chr1_84899098_84899702	0.25	DNASE2B	deoxyribonuclease II beta	25487	0.17
chr11_65059695_65060120	0.25	POLA2	polymerase (DNA directed), alpha 2, accessory subunit	9929	0.12
chr17_64672266_64672417	0.25	AC006947.1		149	0.96
chr9_95824320_95824471	0.25	SUSD3	sushi domain containing 3	3334	0.22
chr4_57570517_57570806	0.25	HOPX	HOP homeobox	22596	0.2
chr9_119134239_119134390	0.25	ENSG00000216182	.	21641	0.17
chr1_244512207_244512358	0.24	C1orf100	chromosome 1 open reading frame 100	3655	0.3
chr19_2736707_2736858	0.24	SLC39A3	solute carrier family 39 (zinc transporter), member 3	2691	0.14
chr13_49234211_49234362	0.24	CYSLTR2	cysteinyl leukotriene receptor 2	46665	0.17
chr19_8261540_8261691	0.24	CERS4	ceramide synthase 4	10005	0.16
chr3_105595835_105595986	0.24	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	7514	0.34
chr5_156731259_156731410	0.24	CYFIP2	cytoplasmic FMR1 interacting protein 2	6711	0.16
chr9_117691491_117691642	0.24	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	1131	0.63
chr2_71772491_71772642	0.24	DYSF	dysferlin	78734	0.11
chr6_35265630_35266434	0.24	DEF6	differentially expressed in FDCP 6 homolog (mouse)	403	0.84
chr13_91068921_91069072	0.24	ENSG00000207858	.	185560	0.03
chr3_13920477_13920889	0.23	WNT7A	wingless-type MMTV integration site family, member 7A	935	0.64
chr11_72437407_72437702	0.23	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	619	0.62
chr9_117381662_117382014	0.23	ENSG00000272241	.	3011	0.2
chr14_55799126_55799413	0.23	RP11-665C16.5		6950	0.25
chr2_112221457_112221687	0.23	ENSG00000266139	.	142904	0.05
chr17_81011527_81011678	0.23	B3GNTL1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1	1916	0.37
chr11_65407442_65407916	0.23	SIPA1	signal-induced proliferation-associated 1	87	0.92
chr18_45856570_45856721	0.23	ZBTB7C	zinc finger and BTB domain containing 7C	8117	0.26
chr10_12647585_12647797	0.23	ENSG00000263584	.	26939	0.23
chr15_38944224_38944375	0.22	C15orf53	chromosome 15 open reading frame 53	44500	0.17
chr3_12185604_12185755	0.22	TIMP4	TIMP metallopeptidase inhibitor 4	15172	0.26
chr1_171632627_171632778	0.22	MYOC	myocilin, trabecular meshwork inducible glucocorticoid response	10879	0.22
chr12_71167942_71168093	0.22	PTPRR	protein tyrosine phosphatase, receptor type, R	14745	0.28
chr4_148703706_148703905	0.22	ENSG00000264274	.	59	0.98
chr18_34021681_34021832	0.22	FHOD3	formin homology 2 domain containing 3	102758	0.08
chr15_68591382_68591806	0.22	FEM1B	fem-1 homolog b (C. elegans)	9044	0.21
chr4_38320095_38320594	0.22	ENSG00000221495	.	80110	0.11
chr5_14594534_14594878	0.22	FAM105A	family with sequence similarity 105, member A	12822	0.24
chr20_43810738_43810889	0.22	PI3	peptidase inhibitor 3, skin-derived	7296	0.15
chr4_57547872_57548147	0.22	HOPX	HOP homeobox	56	0.98
chr19_47660903_47661882	0.22	SAE1	SUMO1 activating enzyme subunit 1	27240	0.13
chr5_114762279_114762430	0.21	FEM1C	fem-1 homolog c (C. elegans)	118237	0.05
chr22_50969510_50970103	0.21	ODF3B	outer dense fiber of sperm tails 3B	700	0.36
chr3_1765848_1765999	0.21	ENSG00000223040	.	364972	0.01
chr1_59395732_59395883	0.21	JUN	jun proto-oncogene	146022	0.04
chr3_53198863_53199290	0.21	PRKCD	protein kinase C, delta	69	0.97
chr1_167586551_167586989	0.21	RCSD1	RCSD domain containing 1	12560	0.19
chr3_156534921_156535559	0.20	LEKR1	leucine, glutamate and lysine rich 1	8849	0.29
chr13_48809687_48810120	0.20	ITM2B	integral membrane protein 2B	2564	0.37
chr3_141866549_141866700	0.20	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	1678	0.34
chrX_153209580_153209767	0.20	RENBP	renin binding protein	466	0.64
chr12_98864880_98865031	0.20	RP11-181C3.1	Uncharacterized protein	32678	0.13
chr2_206633742_206633893	0.20	AC007362.3		5087	0.3
chr6_160241928_160242222	0.19	PNLDC1	poly(A)-specific ribonuclease (PARN)-like domain containing 1	20769	0.12
chr1_159796420_159796571	0.19	SLAMF8	SLAM family member 8	45	0.96
chr5_159214342_159214493	0.19	ADRA1B	adrenoceptor alpha 1B	129373	0.05
chr4_149364707_149365251	0.19	NR3C2	nuclear receptor subfamily 3, group C, member 2	871	0.75
chr11_919324_919475	0.19	CHID1	chitinase domain containing 1	4341	0.12
chr21_16816295_16816446	0.19	ENSG00000212564	.	170232	0.04
chr8_145806326_145806590	0.19	CTD-2517M22.9		2966	0.14
chrX_131159258_131159409	0.19	MST4	Serine/threonine-protein kinase MST4	1697	0.42
chr2_144577318_144577469	0.19	CTD-2252P21.1		43751	0.16
chr14_45722560_45723019	0.19	MIS18BP1	MIS18 binding protein 1	184	0.95
chr3_138839315_138839466	0.19	MRPS22	mitochondrial ribosomal protein S22	10144	0.24
chr13_42294870_42295021	0.19	ENSG00000241406	.	86868	0.09
chr6_111391598_111391749	0.18	SLC16A10	solute carrier family 16 (aromatic amino acid transporter), member 10	17108	0.16
chr3_195641693_195641881	0.18	AC124944.3		2822	0.17
chr16_22217341_22217492	0.18	EEF2K	eukaryotic elongation factor-2 kinase	187	0.95
chr9_2025279_2025430	0.18	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	3409	0.31
chr5_118606701_118606876	0.18	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2339	0.29
chr14_100536973_100537221	0.18	CTD-2376I20.1		4118	0.17
chr19_2281673_2281974	0.18	C19orf35	chromosome 19 open reading frame 35	352	0.73
chr13_99955996_99956281	0.18	GPR183	G protein-coupled receptor 183	3521	0.25
chr2_201991504_201992128	0.18	CFLAR	CASP8 and FADD-like apoptosis regulator	2236	0.22
chr12_1005549_1005700	0.17	WNK1	WNK lysine deficient protein kinase 1	4139	0.25
chr10_33633036_33633187	0.17	NRP1	neuropilin 1	7921	0.28
chr9_86886547_86886817	0.17	RP11-380F14.2		6452	0.29
chr8_91013758_91014471	0.17	DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	369	0.89
chr8_62602537_62602767	0.17	ASPH	aspartate beta-hydroxylase	244	0.94
chr5_135344089_135344240	0.17	TGFBI	transforming growth factor, beta-induced, 68kDa	20420	0.19
chr2_5835221_5835372	0.17	SOX11	SRY (sex determining region Y)-box 11	2497	0.27
chr3_187457028_187457694	0.17	BCL6	B-cell CLL/lymphoma 6	1629	0.41
chr5_141391978_141392551	0.17	GNPDA1	glucosamine-6-phosphate deaminase 1	95	0.96
chr10_43905439_43905728	0.17	HNRNPF	heterogeneous nuclear ribonucleoprotein F	969	0.49
chr3_126074801_126075538	0.17	KLF15	Kruppel-like factor 15	1116	0.51
chr1_38276768_38276919	0.17	C1orf122	chromosome 1 open reading frame 122	2761	0.13
chr10_25465646_25465797	0.17	GPR158-AS1	GPR158 antisense RNA 1	516	0.76
chr2_87785010_87785930	0.17	RP11-1399P15.1		7917	0.31
chr8_102456764_102457065	0.17	ENSG00000239211	.	46753	0.13
chr1_110166249_110166733	0.17	AMPD2	adenosine monophosphate deaminase 2	55	0.94
chr10_74014620_74015053	0.17	DDIT4	DNA-damage-inducible transcript 4	18842	0.13
chr11_114030925_114031331	0.16	ENSG00000221112	.	73477	0.1
chr4_38623548_38623699	0.16	RP11-617D20.1		2573	0.31
chr16_29755026_29755177	0.16	AC009133.17		1467	0.21
chr16_66241067_66241218	0.16	ENSG00000201999	.	94570	0.08
chr9_132082698_132083492	0.16	ENSG00000242281	.	49645	0.12
chr1_46073171_46073322	0.16	NASP	nuclear autoantigenic sperm protein (histone-binding)	5595	0.17
chr3_116582620_116583104	0.16	ENSG00000265433	.	13648	0.25
chr3_13038459_13038610	0.16	IQSEC1	IQ motif and Sec7 domain 1	9998	0.27
chr1_92925539_92925737	0.16	GFI1	growth factor independent 1 transcription repressor	23873	0.21
chr20_34031080_34031231	0.16	GDF5	growth differentiation factor 5	5132	0.12
chr3_134203579_134204194	0.15	CEP63	centrosomal protein 63kDa	699	0.51
chr12_27900729_27900880	0.15	ENSG00000252585	.	5003	0.13
chr11_65185396_65185663	0.15	ENSG00000245532	.	26400	0.09
chr2_169964875_169965026	0.15	AC007556.3		7697	0.23
chr17_692703_692854	0.15	RP11-676J12.8		987	0.43
chr4_10021309_10021460	0.15	SLC2A9	solute carrier family 2 (facilitated glucose transporter), member 9	1723	0.34
chr15_48310054_48310205	0.15	SLC24A5	solute carrier family 24 (sodium/potassium/calcium exchanger), member 5	103040	0.07
chr6_86125936_86126087	0.15	NT5E	5'-nucleotidase, ecto (CD73)	33798	0.22
chr6_209678_209938	0.15	DUSP22	dual specificity phosphatase 22	81822	0.11
chr1_1148809_1149188	0.15	TNFRSF4	tumor necrosis factor receptor superfamily, member 4	514	0.56
chr9_84295213_84295364	0.15	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	6995	0.27
chr9_92255731_92255882	0.15	GADD45G	growth arrest and DNA-damage-inducible, gamma	35853	0.22
chr6_1578010_1578161	0.15	FOXC1	forkhead box C1	32596	0.22
chr9_92079076_92079388	0.15	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	8364	0.24
chr8_77529270_77529421	0.15	ZFHX4-AS1	ZFHX4 antisense RNA 1	669	0.77
chr11_61276967_61277195	0.15	LRRC10B	leucine rich repeat containing 10B	809	0.41
chr14_75807662_75807918	0.14	FOS	FBJ murine osteosarcoma viral oncogene homolog	60894	0.09
chr11_16120543_16120694	0.14	ENSG00000221556	.	25244	0.25
chr2_101664673_101664824	0.14	ENSG00000265860	.	45283	0.11
chr1_216130942_216131093	0.14	RP5-1111A8.3		71093	0.13
chr2_68959667_68959843	0.14	ARHGAP25	Rho GTPase activating protein 25	2158	0.4
chr1_145427603_145427863	0.14	TXNIP	thioredoxin interacting protein	10736	0.12
chr5_148641029_148641180	0.14	AFAP1L1	actin filament associated protein 1-like 1	10330	0.13
chr10_43894836_43894987	0.14	HNRNPF	heterogeneous nuclear ribonucleoprotein F	2117	0.26
chr1_161494601_161494967	0.14	HSPA6	heat shock 70kDa protein 6 (HSP70B')	748	0.56
chr19_2290395_2291381	0.14	LINGO3	leucine rich repeat and Ig domain containing 3	1135	0.28
chr10_14643816_14644958	0.14	FAM107B	family with sequence similarity 107, member B	2001	0.38
chr6_111926441_111927468	0.14	TRAF3IP2	TRAF3 interacting protein 2	120	0.96
chr16_66971123_66971274	0.14	CES2	carboxylesterase 2	2820	0.14
chr16_16308222_16308373	0.14	RP11-517A5.7		8587	0.15
chr8_131024317_131024468	0.14	ENSG00000264653	.	3693	0.2
chr7_77044826_77045681	0.14	GSAP	gamma-secretase activating protein	69	0.98
chr17_28691143_28691377	0.13	ENSG00000201255	.	3779	0.16
chr5_79230796_79230947	0.13	RP11-168A11.1		1531	0.47
chr3_194592076_194592227	0.13	FAM43A	family with sequence similarity 43, member A	185529	0.02
chr4_139230379_139230530	0.13	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	66951	0.14
chr14_65545748_65545899	0.13	RP11-840I19.3		2929	0.21
chr2_145129966_145130117	0.13	GTDC1	glycosyltransferase-like domain containing 1	39958	0.19
chr11_6767215_6767876	0.13	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2	22741	0.11
chr4_121082_121430	0.13	ENSG00000211553	.	8986	0.22
chr9_33162993_33163393	0.13	RP11-326F20.5		3780	0.17
chrX_25031023_25031386	0.13	ARX	aristaless related homeobox	2861	0.36
chr2_39472655_39472806	0.13	CDKL4	cyclin-dependent kinase-like 4	16057	0.19
chr4_87764800_87764951	0.13	SLC10A6	solute carrier family 10 (sodium/bile acid cotransporter), member 6	5541	0.27
chr16_87166401_87166552	0.13	RP11-899L11.3		83045	0.09
chr5_97764803_97764954	0.13	ENSG00000223053	.	210057	0.03
chr10_74089726_74089877	0.13	DNAJB12	DnaJ (Hsp40) homolog, subfamily B, member 12	14918	0.18
chr7_100806219_100806526	0.13	VGF	VGF nerve growth factor inducible	2023	0.17
chr2_175528047_175528198	0.13	WIPF1	WAS/WASL interacting protein family, member 1	19477	0.21
chr11_130783512_130783663	0.13	SNX19	sorting nexin 19	2757	0.4
chr4_24474548_24475165	0.13	ENSG00000265001	.	43401	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of AR_NR3C2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.4	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.3	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.2	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0090398	cellular senescence(GO:0090398)
0.0	0.0	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.3	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.0	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0071220	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.0	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0031045	dense core granule(GO:0031045)
0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4	GO:0030175	filopodium(GO:0030175)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.3	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0004974	leukotriene receptor activity(GO:0004974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	PID IGF1 PATHWAY	IGF1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation