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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for AR_NR3C2

Z-value: 0.87

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Transcription factors associated with AR_NR3C2

Gene Symbol Gene ID Gene Info
AR
ENSG00000169083.11 androgen receptor
NR3C2
ENSG00000151623.10 nuclear receptor subfamily 3 group C member 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chrX_66766516_66766697AR16200.570375-0.655.9e-02Click!
chrX_66952827_66952978AR1641710.0400130.636.8e-02Click!
chrX_66763846_66764061AR5120.891958-0.617.8e-02Click!
chrX_67000951_67001203AR2123460.025037-0.521.5e-01Click!
chrX_66767815_66768085AR29640.426121-0.521.5e-01Click!
chr4_149367147_149367363NR3C214050.5912340.245.3e-01Click!
chr4_149363777_149364242NR3C23370.938175-0.196.2e-01Click!
chr4_149364707_149365251NR3C28710.7506260.156.9e-01Click!
chr4_149368732_149368898NR3C229650.401266-0.147.2e-01Click!
chr4_149363274_149363592NR3C2570.987392-0.127.5e-01Click!

Activity of the AR_NR3C2 motif across conditions

Conditions sorted by the z-value of the AR_NR3C2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_118955810_118956058 0.61 B4GALT4
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
 3070
 0.21
chrX_70760188_70760339 0.57 OGT
 O-linked N-acetylglucosamine (GlcNAc) transferase
 3399
 0.24
chr21_46336780_46336931 0.55 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 2657
 0.15
chr1_172715599_172715750 0.54 FASLG
 Fas ligand (TNF superfamily, member 6)
 87516
 0.09
chr1_95316335_95316486 0.49 ENSG00000237416
 .
 4572
 0.23
chr5_148309668_148309819 0.47 RP11-44B19.1
40160
 0.16
chr6_11381781_11382025 0.46 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 629
 0.82
chr6_35568962_35570321 0.45 ENSG00000212579
 .
 49954
 0.1
chr8_134084504_134084857 0.44 SLA
 Src-like-adaptor
 12077
 0.24
chr16_11794621_11794772 0.43 SNN
 stannin
 32426
 0.12
chr15_40659564_40659826 0.41 RP11-64K12.4
2146
 0.13
chr12_113416849_113417235 0.40 OAS2
 2'-5'-oligoadenylate synthetase 2, 69/71kDa
 697
 0.66
chr6_154568354_154568864 0.40 IPCEF1
 interaction protein for cytohesin exchange factors 1
 53
 0.99
chr11_114186668_114186999 0.40 NNMT
 nicotinamide N-methyltransferase
 17960
 0.18
chr17_79031323_79031474 0.40 BAIAP2
 BAI1-associated protein 2
 17
 0.97
chr12_51713121_51713481 0.40 BIN2
 bridging integrator 2
 4598
 0.18
chr1_10857132_10857283 0.40 CASZ1
 castor zinc finger 1
 500
 0.85
chr13_46959234_46959385 0.39 KIAA0226L
 KIAA0226-like
 2008
 0.32
chr15_86077505_86077656 0.39 AKAP13
 A kinase (PRKA) anchor protein 13
 9691
 0.21
chr6_13448559_13448819 0.38 AL583828.1
37726
 0.13
chr6_36281244_36281395 0.36 C6orf222
 chromosome 6 open reading frame 222
 23343
 0.15
chr13_111213122_111213273 0.35 RAB20
 RAB20, member RAS oncogene family
 883
 0.64
chr6_42013548_42014157 0.35 CCND3
 cyclin D3
 2572
 0.23
chr19_16256933_16257251 0.34 HSH2D
 hematopoietic SH2 domain containing
 2546
 0.18
chr1_112032205_112032457 0.33 ADORA3
 adenosine A3 receptor
 47
 0.91
chr12_52409491_52409642 0.32 GRASP
 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
 4599
 0.14
chr12_26441132_26441283 0.32 RP11-283G6.5
16354
 0.18
chr12_40551802_40551953 0.32 LRRK2
 leucine-rich repeat kinase 2
 38669
 0.17
chr6_25006652_25006894 0.31 ENSG00000244618
 .
 24737
 0.17
chr17_80255361_80255512 0.31 CD7
 CD7 molecule
 19992
 0.09
chr15_63891011_63891162 0.31 FBXL22
 F-box and leucine-rich repeat protein 22
 1185
 0.42
chr1_150540056_150540997 0.30 ENSG00000264508
 .
 1190
 0.22
chr2_99439255_99439699 0.30 ENSG00000238830
 .
 17722
 0.19
chr11_113981757_113982173 0.30 ENSG00000221112
 .
 24314
 0.2
chr12_53985901_53986052 0.30 ATF7
 activating transcription factor 7
 8829
 0.15
chr7_150147431_150147649 0.29 GIMAP8
 GTPase, IMAP family member 8
 178
 0.94
chr15_55547653_55548107 0.29 RAB27A
 RAB27A, member RAS oncogene family
 6647
 0.22
chr4_86953999_86954560 0.29 RP13-514E23.1
19252
 0.19
chr6_6916042_6916314 0.28 ENSG00000240936
 .
 22952
 0.26
chr2_109605420_109605703 0.28 EDAR
 ectodysplasin A receptor
 164
 0.97
chr8_120126680_120126831 0.28 RP11-278I4.2
45734
 0.15
chr2_37817410_37817581 0.28 AC006369.2
9784
 0.26
chr3_73085691_73085907 0.28 ENSG00000238959
 .
 8840
 0.16
chr11_46363477_46363864 0.28 DGKZ
 diacylglycerol kinase, zeta
 3147
 0.2
chrX_118710010_118710161 0.27 UBE2A
 ubiquitin-conjugating enzyme E2A
 1445
 0.35
chrX_53100883_53101580 0.27 TSPYL2
 TSPY-like 2
 10318
 0.18
chr3_81873946_81874241 0.27 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 62781
 0.16
chr1_95018005_95018156 0.27 F3
 coagulation factor III (thromboplastin, tissue factor)
 10724
 0.29
chr11_122655510_122655661 0.26 CRTAM
 cytotoxic and regulatory T cell molecule
 53623
 0.12
chr6_6750463_6750647 0.26 LY86-AS1
 LY86 antisense RNA 1
 127551
 0.05
chr12_106178721_106178872 0.26 NUAK1
 NUAK family, SNF1-like kinase, 1
 299015
 0.01
chr12_728674_728825 0.26 NINJ2
 ninjurin 2
 9165
 0.14
chr1_84899098_84899702 0.25 DNASE2B
 deoxyribonuclease II beta
 25487
 0.17
chr11_65059695_65060120 0.25 POLA2
 polymerase (DNA directed), alpha 2, accessory subunit
 9929
 0.12
chr17_64672266_64672417 0.25 AC006947.1
149
 0.96
chr9_95824320_95824471 0.25 SUSD3
 sushi domain containing 3
 3334
 0.22
chr4_57570517_57570806 0.25 HOPX
 HOP homeobox
 22596
 0.2
chr9_119134239_119134390 0.25 ENSG00000216182
 .
 21641
 0.17
chr1_244512207_244512358 0.24 C1orf100
 chromosome 1 open reading frame 100
 3655
 0.3
chr19_2736707_2736858 0.24 SLC39A3
 solute carrier family 39 (zinc transporter), member 3
 2691
 0.14
chr13_49234211_49234362 0.24 CYSLTR2
 cysteinyl leukotriene receptor 2
 46665
 0.17
chr19_8261540_8261691 0.24 CERS4
 ceramide synthase 4
 10005
 0.16
chr3_105595835_105595986 0.24 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 7514
 0.34
chr5_156731259_156731410 0.24 CYFIP2
 cytoplasmic FMR1 interacting protein 2
 6711
 0.16
chr9_117691491_117691642 0.24 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
 1131
 0.63
chr2_71772491_71772642 0.24 DYSF
 dysferlin
 78734
 0.11
chr6_35265630_35266434 0.24 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 403
 0.84
chr13_91068921_91069072 0.24 ENSG00000207858
 .
 185560
 0.03
chr3_13920477_13920889 0.23 WNT7A
 wingless-type MMTV integration site family, member 7A
 935
 0.64
chr11_72437407_72437702 0.23 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
 619
 0.62
chr9_117381662_117382014 0.23 ENSG00000272241
 .
 3011
 0.2
chr14_55799126_55799413 0.23 RP11-665C16.5
6950
 0.25
chr2_112221457_112221687 0.23 ENSG00000266139
 .
 142904
 0.05
chr17_81011527_81011678 0.23 B3GNTL1
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
 1916
 0.37
chr11_65407442_65407916 0.23 SIPA1
 signal-induced proliferation-associated 1
 87
 0.92
chr18_45856570_45856721 0.23 ZBTB7C
 zinc finger and BTB domain containing 7C
 8117
 0.26
chr10_12647585_12647797 0.23 ENSG00000263584
 .
 26939
 0.23
chr15_38944224_38944375 0.22 C15orf53
 chromosome 15 open reading frame 53
 44500
 0.17
chr3_12185604_12185755 0.22 TIMP4
 TIMP metallopeptidase inhibitor 4
 15172
 0.26
chr1_171632627_171632778 0.22 MYOC
 myocilin, trabecular meshwork inducible glucocorticoid response
 10879
 0.22
chr12_71167942_71168093 0.22 PTPRR
 protein tyrosine phosphatase, receptor type, R
 14745
 0.28
chr4_148703706_148703905 0.22 ENSG00000264274
 .
 59
 0.98
chr18_34021681_34021832 0.22 FHOD3
 formin homology 2 domain containing 3
 102758
 0.08
chr15_68591382_68591806 0.22 FEM1B
 fem-1 homolog b (C. elegans)
 9044
 0.21
chr4_38320095_38320594 0.22 ENSG00000221495
 .
 80110
 0.11
chr5_14594534_14594878 0.22 FAM105A
 family with sequence similarity 105, member A
 12822
 0.24
chr20_43810738_43810889 0.22 PI3
 peptidase inhibitor 3, skin-derived
 7296
 0.15
chr4_57547872_57548147 0.22 HOPX
 HOP homeobox
 56
 0.98
chr19_47660903_47661882 0.22 SAE1
 SUMO1 activating enzyme subunit 1
 27240
 0.13
chr5_114762279_114762430 0.21 FEM1C
 fem-1 homolog c (C. elegans)
 118237
 0.05
chr22_50969510_50970103 0.21 ODF3B
 outer dense fiber of sperm tails 3B
 700
 0.36
chr3_1765848_1765999 0.21 ENSG00000223040
 .
 364972
 0.01
chr1_59395732_59395883 0.21 JUN
 jun proto-oncogene
 146022
 0.04
chr3_53198863_53199290 0.21 PRKCD
 protein kinase C, delta
 69
 0.97
chr1_167586551_167586989 0.21 RCSD1
 RCSD domain containing 1
 12560
 0.19
chr3_156534921_156535559 0.20 LEKR1
 leucine, glutamate and lysine rich 1
 8849
 0.29
chr13_48809687_48810120 0.20 ITM2B
 integral membrane protein 2B
 2564
 0.37
chr3_141866549_141866700 0.20 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
 1678
 0.34
chrX_153209580_153209767 0.20 RENBP
 renin binding protein
 466
 0.64
chr12_98864880_98865031 0.20 RP11-181C3.1
 Uncharacterized protein
 32678
 0.13
chr2_206633742_206633893 0.20 AC007362.3
5087
 0.3
chr6_160241928_160242222 0.19 PNLDC1
 poly(A)-specific ribonuclease (PARN)-like domain containing 1
 20769
 0.12
chr1_159796420_159796571 0.19 SLAMF8
 SLAM family member 8
 45
 0.96
chr5_159214342_159214493 0.19 ADRA1B
 adrenoceptor alpha 1B
 129373
 0.05
chr4_149364707_149365251 0.19 NR3C2
 nuclear receptor subfamily 3, group C, member 2
 871
 0.75
chr11_919324_919475 0.19 CHID1
 chitinase domain containing 1
 4341
 0.12
chr21_16816295_16816446 0.19 ENSG00000212564
 .
 170232
 0.04
chr8_145806326_145806590 0.19 CTD-2517M22.9
2966
 0.14
chrX_131159258_131159409 0.19 MST4
 Serine/threonine-protein kinase MST4
 1697
 0.42
chr2_144577318_144577469 0.19 CTD-2252P21.1
43751
 0.16
chr14_45722560_45723019 0.19 MIS18BP1
 MIS18 binding protein 1
 184
 0.95
chr3_138839315_138839466 0.19 MRPS22
 mitochondrial ribosomal protein S22
 10144
 0.24
chr13_42294870_42295021 0.19 ENSG00000241406
 .
 86868
 0.09
chr6_111391598_111391749 0.18 SLC16A10
 solute carrier family 16 (aromatic amino acid transporter), member 10
 17108
 0.16
chr3_195641693_195641881 0.18 AC124944.3
2822
 0.17
chr16_22217341_22217492 0.18 EEF2K
 eukaryotic elongation factor-2 kinase
 187
 0.95
chr9_2025279_2025430 0.18 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 3409
 0.31
chr5_118606701_118606876 0.18 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 2339
 0.29
chr14_100536973_100537221 0.18 CTD-2376I20.1
4118
 0.17
chr19_2281673_2281974 0.18 C19orf35
 chromosome 19 open reading frame 35
 352
 0.73
chr13_99955996_99956281 0.18 GPR183
 G protein-coupled receptor 183
 3521
 0.25
chr2_201991504_201992128 0.18 CFLAR
 CASP8 and FADD-like apoptosis regulator
 2236
 0.22
chr12_1005549_1005700 0.17 WNK1
 WNK lysine deficient protein kinase 1
 4139
 0.25
chr10_33633036_33633187 0.17 NRP1
 neuropilin 1
 7921
 0.28
chr9_86886547_86886817 0.17 RP11-380F14.2
6452
 0.29
chr8_91013758_91014471 0.17 DECR1
 2,4-dienoyl CoA reductase 1, mitochondrial
 369
 0.89
chr8_62602537_62602767 0.17 ASPH
 aspartate beta-hydroxylase
 244
 0.94
chr5_135344089_135344240 0.17 TGFBI
 transforming growth factor, beta-induced, 68kDa
 20420
 0.19
chr2_5835221_5835372 0.17 SOX11
 SRY (sex determining region Y)-box 11
 2497
 0.27
chr3_187457028_187457694 0.17 BCL6
 B-cell CLL/lymphoma 6
 1629
 0.41
chr5_141391978_141392551 0.17 GNPDA1
 glucosamine-6-phosphate deaminase 1
 95
 0.96
chr10_43905439_43905728 0.17 HNRNPF
 heterogeneous nuclear ribonucleoprotein F
 969
 0.49
chr3_126074801_126075538 0.17 KLF15
 Kruppel-like factor 15
 1116
 0.51
chr1_38276768_38276919 0.17 C1orf122
 chromosome 1 open reading frame 122
 2761
 0.13
chr10_25465646_25465797 0.17 GPR158-AS1
 GPR158 antisense RNA 1
 516
 0.76
chr2_87785010_87785930 0.17 RP11-1399P15.1
7917
 0.31
chr8_102456764_102457065 0.17 ENSG00000239211
 .
 46753
 0.13
chr1_110166249_110166733 0.17 AMPD2
 adenosine monophosphate deaminase 2
 55
 0.94
chr10_74014620_74015053 0.17 DDIT4
 DNA-damage-inducible transcript 4
 18842
 0.13
chr11_114030925_114031331 0.16 ENSG00000221112
 .
 73477
 0.1
chr4_38623548_38623699 0.16 RP11-617D20.1
2573
 0.31
chr16_29755026_29755177 0.16 AC009133.17
1467
 0.21
chr16_66241067_66241218 0.16 ENSG00000201999
 .
 94570
 0.08
chr9_132082698_132083492 0.16 ENSG00000242281
 .
 49645
 0.12
chr1_46073171_46073322 0.16 NASP
 nuclear autoantigenic sperm protein (histone-binding)
 5595
 0.17
chr3_116582620_116583104 0.16 ENSG00000265433
 .
 13648
 0.25
chr3_13038459_13038610 0.16 IQSEC1
 IQ motif and Sec7 domain 1
 9998
 0.27
chr1_92925539_92925737 0.16 GFI1
 growth factor independent 1 transcription repressor
 23873
 0.21
chr20_34031080_34031231 0.16 GDF5
 growth differentiation factor 5
 5132
 0.12
chr3_134203579_134204194 0.15 CEP63
 centrosomal protein 63kDa
 699
 0.51
chr12_27900729_27900880 0.15 ENSG00000252585
 .
 5003
 0.13
chr11_65185396_65185663 0.15 ENSG00000245532
 .
 26400
 0.09
chr2_169964875_169965026 0.15 AC007556.3
7697
 0.23
chr17_692703_692854 0.15 RP11-676J12.8
987
 0.43
chr4_10021309_10021460 0.15 SLC2A9
 solute carrier family 2 (facilitated glucose transporter), member 9
 1723
 0.34
chr15_48310054_48310205 0.15 SLC24A5
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
 103040
 0.07
chr6_86125936_86126087 0.15 NT5E
 5'-nucleotidase, ecto (CD73)
 33798
 0.22
chr6_209678_209938 0.15 DUSP22
 dual specificity phosphatase 22
 81822
 0.11
chr1_1148809_1149188 0.15 TNFRSF4
 tumor necrosis factor receptor superfamily, member 4
 514
 0.56
chr9_84295213_84295364 0.15 TLE1
 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
 6995
 0.27
chr9_92255731_92255882 0.15 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 35853
 0.22
chr6_1578010_1578161 0.15 FOXC1
 forkhead box C1
 32596
 0.22
chr9_92079076_92079388 0.15 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 8364
 0.24
chr8_77529270_77529421 0.15 ZFHX4-AS1
 ZFHX4 antisense RNA 1
 669
 0.77
chr11_61276967_61277195 0.15 LRRC10B
 leucine rich repeat containing 10B
 809
 0.41
chr14_75807662_75807918 0.14 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 60894
 0.09
chr11_16120543_16120694 0.14 ENSG00000221556
 .
 25244
 0.25
chr2_101664673_101664824 0.14 ENSG00000265860
 .
 45283
 0.11
chr1_216130942_216131093 0.14 RP5-1111A8.3
71093
 0.13
chr2_68959667_68959843 0.14 ARHGAP25
 Rho GTPase activating protein 25
 2158
 0.4
chr1_145427603_145427863 0.14 TXNIP
 thioredoxin interacting protein
 10736
 0.12
chr5_148641029_148641180 0.14 AFAP1L1
 actin filament associated protein 1-like 1
 10330
 0.13
chr10_43894836_43894987 0.14 HNRNPF
 heterogeneous nuclear ribonucleoprotein F
 2117
 0.26
chr1_161494601_161494967 0.14 HSPA6
 heat shock 70kDa protein 6 (HSP70B')
 748
 0.56
chr19_2290395_2291381 0.14 LINGO3
 leucine rich repeat and Ig domain containing 3
 1135
 0.28
chr10_14643816_14644958 0.14 FAM107B
 family with sequence similarity 107, member B
 2001
 0.38
chr6_111926441_111927468 0.14 TRAF3IP2
 TRAF3 interacting protein 2
 120
 0.96
chr16_66971123_66971274 0.14 CES2
 carboxylesterase 2
 2820
 0.14
chr16_16308222_16308373 0.14 RP11-517A5.7
8587
 0.15
chr8_131024317_131024468 0.14 ENSG00000264653
 .
 3693
 0.2
chr7_77044826_77045681 0.14 GSAP
 gamma-secretase activating protein
 69
 0.98
chr17_28691143_28691377 0.13 ENSG00000201255
 .
 3779
 0.16
chr5_79230796_79230947 0.13 RP11-168A11.1
1531
 0.47
chr3_194592076_194592227 0.13 FAM43A
 family with sequence similarity 43, member A
 185529
 0.02
chr4_139230379_139230530 0.13 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 66951
 0.14
chr14_65545748_65545899 0.13 RP11-840I19.3
2929
 0.21
chr2_145129966_145130117 0.13 GTDC1
 glycosyltransferase-like domain containing 1
 39958
 0.19
chr11_6767215_6767876 0.13 OR2AG2
 olfactory receptor, family 2, subfamily AG, member 2
 22741
 0.11
chr4_121082_121430 0.13 ENSG00000211553
 .
 8986
 0.22
chr9_33162993_33163393 0.13 RP11-326F20.5
3780
 0.17
chrX_25031023_25031386 0.13 ARX
 aristaless related homeobox
 2861
 0.36
chr2_39472655_39472806 0.13 CDKL4
 cyclin-dependent kinase-like 4
 16057
 0.19
chr4_87764800_87764951 0.13 SLC10A6
 solute carrier family 10 (sodium/bile acid cotransporter), member 6
 5541
 0.27
chr16_87166401_87166552 0.13 RP11-899L11.3
83045
 0.09
chr5_97764803_97764954 0.13 ENSG00000223053
 .
 210057
 0.03
chr10_74089726_74089877 0.13 DNAJB12
 DnaJ (Hsp40) homolog, subfamily B, member 12
 14918
 0.18
chr7_100806219_100806526 0.13 VGF
 VGF nerve growth factor inducible
 2023
 0.17
chr2_175528047_175528198 0.13 WIPF1
 WAS/WASL interacting protein family, member 1
 19477
 0.21
chr11_130783512_130783663 0.13 SNX19
 sorting nexin 19
 2757
 0.4
chr4_24474548_24475165 0.13 ENSG00000265001
 .
 43401
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of AR_NR3C2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.1 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.3 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.1 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.2 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.0 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0090398 cellular senescence(GO:0090398)
0.0 0.0 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.0 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.0 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0071220 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.0 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0030175 filopodium(GO:0030175)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.0 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation