Results for ATF4

Z-value: 0.35

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Transcription factors associated with ATF4

Gene Symbol	Gene ID	Gene Info
ATF4 Ensembl NCBI GeneCards UniProt	ENSG00000128272.10	activating transcription factor 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr22_39916629_39916983	ATF4	237	0.900609	-0.59	9.3e-02	Click!
chr22_39915742_39916052	ATF4	197	0.920332	-0.52	1.5e-01	Click!
chr22_39917795_39917946	ATF4	1301	0.361515	-0.52	1.5e-01	Click!
chr22_39917253_39917786	ATF4	950	0.477950	-0.50	1.7e-01	Click!
chr22_39916301_39916487	ATF4	175	0.930203	-0.49	1.8e-01	Click!

Activity of the ATF4 motif across conditions

Conditions sorted by the z-value of the ATF4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr22_50919615_50920637	0.14	ADM2	adrenomedullin 2	27	0.94
chr5_153691070_153691221	0.14	ENSG00000221070	.	28541	0.16
chr3_5239428_5239587	0.12	EDEM1	ER degradation enhancer, mannosidase alpha-like 1	9473	0.15
chr1_59966766_59966917	0.11	FGGY	FGGY carbohydrate kinase domain containing	52749	0.18
chr20_43124073_43124404	0.10	SERINC3	serine incorporator 3	9294	0.12
chr13_95133005_95133156	0.10	DCT	dopachrome tautomerase	1144	0.56
chr1_234039912_234040198	0.09	SLC35F3	solute carrier family 35, member F3	624	0.81
chr19_19513882_19514033	0.09	CTB-184G21.3		545	0.68
chrX_49853365_49853516	0.09	CLCN5	chloride channel, voltage-sensitive 5	19284	0.14
chr6_88609819_88609970	0.09	ENSG00000211983	.	52544	0.13
chr8_96247980_96248131	0.08	C8orf37	chromosome 8 open reading frame 37	33374	0.2
chr13_114263460_114263611	0.08	TFDP1	transcription factor Dp-1	23794	0.17
chr4_185734510_185734661	0.08	RP11-701P16.2	Uncharacterized protein	188	0.91
chr11_20000428_20000721	0.08	NAV2-AS3	NAV2 antisense RNA 3	2309	0.36
chr11_70262295_70262446	0.07	CTTN	cortactin	3861	0.17
chr10_28031252_28032104	0.07	MKX	mohawk homeobox	796	0.61
chr1_8278863_8279147	0.07	ENSG00000200975	.	12348	0.21
chr11_70163755_70163906	0.07	CTA-797E19.1		2204	0.21
chr16_14994956_14995107	0.07	ENSG00000257264	.	334	0.79
chr19_40590982_40591133	0.07	ZNF780A	zinc finger protein 780A	5085	0.16
chr9_36144726_36145049	0.07	GLIPR2	GLI pathogenesis-related 2	8145	0.19
chr5_159510080_159510300	0.07	PWWP2A	PWWP domain containing 2A	36239	0.14
chr1_117079785_117079936	0.07	CD58	CD58 molecule	7352	0.18
chr6_121329824_121330111	0.07	ENSG00000200310	.	322200	0.01
chrX_50200272_50200423	0.07	CCNB3	cyclin B3	172807	0.03
chr11_72546027_72546178	0.06	FCHSD2	FCH and double SH3 domains 2	8456	0.14
chr12_29588619_29588770	0.06	OVCH1	ovochymase 1	8475	0.22
chr9_123495329_123495480	0.06	MEGF9	multiple EGF-like-domains 9	18656	0.21
chr1_207509019_207509170	0.06	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	13958	0.26
chr5_142373997_142374148	0.06	ARHGAP26	Rho GTPase activating protein 26	42689	0.2
chr5_52327571_52327722	0.06	CTD-2175A23.1		41538	0.14
chr2_46769122_46769585	0.06	ATP6V1E2	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2	343	0.61
chr11_7998839_7999271	0.06	EIF3F	eukaryotic translation initiation factor 3, subunit F	7257	0.13
chr2_51447556_51447707	0.05	NRXN1	neurexin 1	187957	0.03
chr9_40632604_40633916	0.05	SPATA31A3	SPATA31 subfamily A, member 3	67031	0.14
chr10_29916878_29917029	0.05	SVIL	supervillin	6948	0.21
chr11_102096966_102097117	0.05	RP11-864G5.3		4612	0.23
chr11_35195556_35195728	0.05	CD44	CD44 molecule (Indian blood group)	2476	0.25
chr2_17774779_17774930	0.05	VSNL1	visinin-like 1	52427	0.16
chr6_24922511_24922662	0.05	FAM65B	family with sequence similarity 65, member B	11391	0.23
chr12_65131454_65131605	0.05	GNS	glucosamine (N-acetyl)-6-sulfatase	7141	0.15
chr17_60859401_60859552	0.05	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	22124	0.2
chr19_54327344_54327551	0.05	NLRP12	NLR family, pyrin domain containing 12	124	0.86
chr9_41432727_41433091	0.05	SPATA31A5	SPATA31 subfamily A, member 5	67770	0.13
chr8_36720546_36720697	0.05	KCNU1	potassium channel, subfamily U, member 1	65802	0.14
chr17_68166405_68166607	0.05	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2	830	0.45
chr20_47368252_47368403	0.05	ENSG00000251876	.	12342	0.27
chr18_3597270_3597421	0.05	DLGAP1-AS1	DLGAP1 antisense RNA 1	2892	0.21
chr9_39287322_39287607	0.05	CNTNAP3	contactin associated protein-like 3	628	0.81
chrX_19700900_19701219	0.05	SH3KBP1	SH3-domain kinase binding protein 1	11943	0.3
chr21_44495024_44495938	0.05	CBS	cystathionine-beta-synthase	460	0.8
chr9_65576390_65577630	0.04	SPATA31A7	SPATA31 subfamily A, member 7	67400	0.15
chr20_61303254_61303405	0.04	SLCO4A1	solute carrier organic anion transporter family, member 4A1	4164	0.14
chr2_192058733_192058884	0.04	STAT4	signal transducer and activator of transcription 4	42486	0.15
chr9_39816703_39816854	0.04	SPATA31A2	SPATA31 subfamily A, member 2	68197	0.13
chr2_242269478_242269629	0.04	SEPT2	septin 2	5705	0.15
chr4_68303805_68303956	0.04	ENSG00000206629	.	8408	0.29
chr1_158977592_158977743	0.04	IFI16	interferon, gamma-inducible protein 16	1118	0.53
chr11_7621443_7621674	0.04	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	3141	0.25
chr2_87782164_87782461	0.04	RP11-1399P15.1		4759	0.34
chr11_118111552_118111703	0.04	MPZL3	myelin protein zero-like 3	11435	0.13
chr1_232756314_232756465	0.04	SIPA1L2	signal-induced proliferation-associated 1 like 2	59085	0.14
chr3_39372377_39372528	0.04	CCR8	chemokine (C-C motif) receptor 8	1188	0.47
chr3_10231782_10231933	0.04	IRAK2	interleukin-1 receptor-associated kinase 2	25308	0.1
chr19_31807183_31807454	0.04	AC007796.1		32469	0.2
chr5_53736380_53736531	0.04	HSPB3	heat shock 27kDa protein 3	14990	0.27
chr15_31727307_31728004	0.04	KLF13	Kruppel-like factor 13	69298	0.13
chr1_78392239_78392485	0.04	NEXN	nexilin (F actin binding protein)	8549	0.18
chr3_111260963_111261300	0.04	CD96	CD96 molecule	134	0.97
chr22_22417650_22417801	0.04	IGLVV-66	immunoglobulin lambda variable (V)-66 (pseudogene)	2236	0.12
chr15_86099150_86099301	0.04	AKAP13	A kinase (PRKA) anchor protein 13	548	0.77
chr2_197071722_197071873	0.04	ENSG00000239161	.	8249	0.2
chr17_29645268_29645505	0.04	CTD-2370N5.3		272	0.86
chr12_57349520_57349671	0.04	RDH16	retinol dehydrogenase 16 (all-trans)	2508	0.18
chr1_29254208_29254684	0.04	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	13355	0.18
chr8_1968982_1969133	0.04	MYOM2	myomesin 2	24098	0.23
chr16_16393606_16393757	0.04	ENSG00000257381	.	335	0.78
chr9_22006120_22006693	0.04	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	2546	0.22
chr5_54456050_54456451	0.03	GPX8	glutathione peroxidase 8 (putative)	252	0.86
chr15_66662520_66662887	0.03	TIPIN	TIMELESS interacting protein	13649	0.11
chr13_46870401_46870552	0.03	ENSG00000252854	.	46399	0.12
chr1_52520143_52521733	0.03	TXNDC12	thioredoxin domain containing 12 (endoplasmic reticulum)	75	0.92
chr14_55769874_55770025	0.03	FBXO34	F-box protein 34	31077	0.17
chr1_186782436_186782587	0.03	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	15574	0.29
chr7_98000760_98000949	0.03	BAIAP2L1	BAI1-associated protein 2-like 1	29526	0.17
chr10_14799506_14799657	0.03	FAM107B	family with sequence similarity 107, member B	17315	0.21
chr11_34393219_34393432	0.03	ABTB2	ankyrin repeat and BTB (POZ) domain containing 2	13770	0.25
chr14_80296454_80296605	0.03	RP11-242P2.1		38923	0.23
chrX_12974492_12974668	0.03	TMSB4X	thymosin beta 4, X-linked	18647	0.19
chr13_30168298_30169638	0.03	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	857	0.74
chr8_49831086_49831370	0.03	SNAI2	snail family zinc finger 2	2760	0.41
chr15_55695695_55695873	0.03	CCPG1	cell cycle progression 1	4466	0.19
chr3_171805158_171805309	0.03	FNDC3B	fibronectin type III domain containing 3B	39531	0.2
chr1_160611300_160611550	0.03	SLAMF1	signaling lymphocytic activation molecule family member 1	5386	0.18
chr10_65227518_65227669	0.03	JMJD1C	jumonji domain containing 1C	1871	0.34
chr19_10865922_10866073	0.03	ENSG00000265879	.	24933	0.1
chr7_115912354_115912783	0.03	TES	testis derived transcript (3 LIM domains)	22079	0.19
chr20_23238774_23238931	0.03	NXT1	NTF2-like export factor 1	92521	0.05
chr16_85558650_85558942	0.03	ENSG00000264203	.	83698	0.08
chr17_45743155_45743306	0.03	KPNB1	karyopherin (importin) beta 1	2501	0.2
chr6_54063055_54063206	0.03	MLIP	muscular LMNA-interacting protein	86822	0.09
chr5_126097836_126098030	0.03	ENSG00000252185	.	6824	0.23
chr6_41168130_41168571	0.03	TREML2	triggering receptor expressed on myeloid cells-like 2	582	0.65
chr1_244816518_244817656	0.03	DESI2	desumoylating isopeptidase 2	34	0.98
chr12_8608652_8608803	0.03	CLEC6A	C-type lectin domain family 6, member A	205	0.93
chr22_17599343_17599494	0.03	CECR6	cat eye syndrome chromosome region, candidate 6	2725	0.2
chr5_131795223_131795415	0.03	ENSG00000202533	.	8520	0.13
chr4_74587190_74587341	0.03	IL8	interleukin 8	18958	0.22
chr8_126590914_126591065	0.03	ENSG00000266452	.	134182	0.05
chr4_15680427_15680704	0.03	FBXL5	F-box and leucine-rich repeat protein 5	2612	0.25
chr17_38498589_38499681	0.03	CTD-2267D19.2		253	0.69
chr1_164717921_164718072	0.03	PBX1	pre-B-cell leukemia homeobox 1	24153	0.17
chr9_110310779_110311295	0.03	KLF4	Kruppel-like factor 4 (gut)	58274	0.13
chrX_110339181_110339857	0.03	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	69	0.99
chr20_19052062_19052213	0.03	ENSG00000264669	.	54292	0.15
chrX_9431281_9431551	0.03	TBL1X	transducin (beta)-like 1X-linked	45	0.99
chr10_63995828_63995979	0.03	RTKN2	rhotekin 2	119	0.98
chr15_51172886_51173037	0.03	AP4E1	adaptor-related protein complex 4, epsilon 1 subunit	27909	0.22
chr18_13464907_13465379	0.02	LDLRAD4	low density lipoprotein receptor class A domain containing 4	129	0.93
chr3_58321087_58321238	0.02	PXK	PX domain containing serine/threonine kinase	2129	0.32
chr2_54517166_54517317	0.02	TSPYL6	TSPY-like 6	33832	0.18
chr1_154130279_154130430	0.02	NUP210L	nucleoporin 210kDa-like	2762	0.15
chr11_47241983_47242228	0.02	RP11-17G12.2		1197	0.29
chr9_117657275_117657426	0.02	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	35347	0.2
chr12_67928012_67928180	0.02	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	114022	0.07
chr1_43036666_43036817	0.02	ENSG00000200254	.	2037	0.33
chr10_97624941_97625092	0.02	RP11-429G19.3		31751	0.15
chr9_107826999_107827201	0.02	ENSG00000201583	.	31937	0.22
chr6_163730438_163730589	0.02	ENSG00000239136	.	82571	0.1
chr18_41514870_41515021	0.02	ENSG00000202250	.	102715	0.08
chr20_14985685_14985836	0.02	ENSG00000199803	.	16545	0.2
chr3_62573316_62573467	0.02	CADPS	Ca++-dependent secretion activator	2470	0.43
chr2_30695318_30695469	0.02	LCLAT1	lysocardiolipin acyltransferase 1	25124	0.22
chr9_110377598_110377749	0.02	ENSG00000202308	.	47854	0.17
chr4_40731755_40731906	0.02	NSUN7	NOP2/Sun domain family, member 7	20084	0.21
chr3_33687128_33687279	0.02	CLASP2	cytoplasmic linker associated protein 2	208	0.97
chr2_225543043_225543293	0.02	CUL3	cullin 3	93058	0.09
chr13_40889454_40889605	0.02	ENSG00000207458	.	88565	0.09
chr14_60239555_60239706	0.02	RTN1	reticulon 1	98054	0.07
chr1_212781685_212782134	0.02	ATF3	activating transcription factor 3	103	0.96
chr10_90031525_90031822	0.02	ENSG00000200891	.	277221	0.01
chr19_47134901_47135052	0.02	GNG8	guanine nucleotide binding protein (G protein), gamma 8	2966	0.12
chr16_9166928_9167149	0.02	C16orf72	chromosome 16 open reading frame 72	18467	0.16
chr8_25058747_25058898	0.02	DOCK5	dedicator of cytokinesis 5	16442	0.23
chr3_179754024_179754473	0.02	PEX5L	peroxisomal biogenesis factor 5-like	310	0.94
chr18_72235350_72235501	0.02	RP11-231E4.3		6090	0.21
chr14_95991348_95991499	0.02	ENSG00000252481	.	8543	0.14
chr19_1259849_1260000	0.02	CIRBP	cold inducible RNA binding protein	540	0.56
chr17_53573866_53574017	0.02	ENSG00000200107	.	55230	0.15
chr15_89181571_89183025	0.02	ISG20	interferon stimulated exonuclease gene 20kDa	114	0.96
chr5_139680846_139680997	0.02	PFDN1	prefoldin subunit 1	1747	0.3
chr2_85972153_85972528	0.02	ATOH8	atonal homolog 8 (Drosophila)	8677	0.15
chr8_61021784_61021935	0.02	CA8	carbonic anhydrase VIII	172112	0.04
chr21_34712478_34712629	0.02	IFNAR1	interferon (alpha, beta and omega) receptor 1	15275	0.17
chr17_4802345_4802927	0.02	C17orf107	chromosome 17 open reading frame 107	77	0.92
chr12_47617851_47618002	0.02	PCED1B	PC-esterase domain containing 1B	598	0.78
chr8_35828319_35828470	0.02	AC012215.1	Uncharacterized protein	179029	0.03
chr3_71115813_71116298	0.02	FOXP1	forkhead box P1	1137	0.67
chr7_75575266_75575417	0.02	POR	P450 (cytochrome) oxidoreductase	701	0.6
chr4_185235485_185235636	0.02	ENSG00000244512	.	35471	0.16
chr16_88271666_88271817	0.02	ZNF469	zinc finger protein 469	222138	0.02
chrX_53117609_53118006	0.02	TSPYL2	TSPY-like 2	6244	0.19
chr11_11418436_11418587	0.02	CSNK2A3	casein kinase 2, alpha 3 polypeptide	43607	0.17
chr8_130957137_130957288	0.02	FAM49B	family with sequence similarity 49, member B	5094	0.24
chr21_42217900_42218266	0.02	DSCAM	Down syndrome cell adhesion molecule	982	0.71
chr19_47843854_47844005	0.02	C5AR2	complement component 5a receptor 2	111	0.95
chr6_134323821_134323972	0.02	TBPL1	TBP-like 1	49534	0.14
chr9_104207627_104207869	0.02	ALDOB	aldolase B, fructose-bisphosphate	9643	0.15
chr8_23456525_23456676	0.02	ENSG00000252067	.	1051	0.5
chr10_54463336_54463751	0.02	RP11-556E13.1		51626	0.16
chr3_30014109_30014328	0.02	RBMS3-AS1	RBMS3 antisense RNA 1	38571	0.22
chr10_112676510_112676710	0.02	BBIP1	BBSome interacting protein 1	2084	0.21
chr10_90358006_90358157	0.02	LIPJ	lipase, family member J	3578	0.22
chrX_15806325_15806476	0.02	ZRSR2	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2	2195	0.32
chrX_121981496_121981647	0.02	ENSG00000212321	.	7292	0.34
chr3_149371362_149371801	0.02	WWTR1-AS1	WWTR1 antisense RNA 1	3226	0.2
chr5_75764900_75765051	0.02	IQGAP2	IQ motif containing GTPase activating protein 2	64726	0.13
chr11_77185235_77185792	0.02	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	167	0.92
chr12_65032414_65032565	0.02	RP11-338E21.2		10365	0.12
chr4_188049686_188049901	0.02	ENSG00000252382	.	271183	0.02
chr11_14310125_14310327	0.02	RRAS2	related RAS viral (r-ras) oncogene homolog 2	7179	0.24
chr20_30793303_30793454	0.02	PLAGL2	pleiomorphic adenoma gene-like 2	2216	0.22
chr8_127569289_127570002	0.02	RP11-89K10.1		475	0.43
chr17_14680546_14680697	0.02	ENSG00000238806	.	460579	0.01
chr3_3843603_3843999	0.02	LRRN1	leucine rich repeat neuronal 1	2680	0.43
chr21_43739991_43740142	0.02	TFF3	trefoil factor 3 (intestinal)	4305	0.17
chr16_69363414_69364502	0.02	PDF	peptide deformylase (mitochondrial)	540	0.59
chr11_75473950_75474101	0.02	DGAT2	diacylglycerol O-acyltransferase 2	3468	0.13
chr17_70358508_70358679	0.02	SOX9	SRY (sex determining region Y)-box 9	241432	0.02
chr4_154064855_154065006	0.02	TRIM2	tripartite motif containing 2	8715	0.28
chr12_68661800_68661951	0.02	IL22	interleukin 22	14488	0.21
chr6_5936596_5936747	0.02	ENSG00000239472	.	17594	0.25
chr9_21563269_21563420	0.02	MIR31HG	MIR31 host gene (non-protein coding)	3676	0.23
chr9_3508436_3508948	0.02	RFX3	regulatory factor X, 3 (influences HLA class II expression)	17291	0.25
chrX_135258076_135258227	0.02	FHL1	four and a half LIM domains 1	6066	0.24
chr3_146272331_146272482	0.02	PLSCR1	phospholipid scramblase 1	9755	0.18
chrX_24043946_24044693	0.02	KLHL15	kelch-like family member 15	984	0.59
chr7_6481952_6482201	0.02	DAGLB	diacylglycerol lipase, beta	5487	0.18
chr9_32741891_32742042	0.02	ENSG00000221696	.	22328	0.18
chr1_198227931_198228157	0.02	NEK7	NIMA-related kinase 7	38115	0.23