Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ATF5

Z-value: 0.97

Motif logo

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Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ENSG00000169136.4 ATF5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ATF5chr19_50431051_504312058310.2917770.363.4e-01Click!
ATF5chr19_50431234_504314746050.3982320.255.1e-01Click!
ATF5chr19_50433515_504336771200.786786-0.255.2e-01Click!
ATF5chr19_50432415_50432712840.418754-0.245.4e-01Click!
ATF5chr19_50431928_504324062080.622212-0.078.6e-01Click!

Activity of the ATF5 motif across conditions

Conditions sorted by the z-value of the ATF5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_82413627_82413778 0.35 RASGEF1B
RasGEF domain family, member 1B
20633
0.28
chr1_27890528_27890679 0.29 RP1-159A19.4

38287
0.11
chr3_194456850_194457149 0.27 FAM43A
family with sequence similarity 43, member A
50377
0.11
chr7_115670709_115671033 0.27 TFEC
transcription factor EC
4
0.99
chr10_30842846_30843212 0.27 ENSG00000239744
.
1804
0.44
chr2_103506737_103506888 0.25 TMEM182
transmembrane protein 182
128340
0.06
chr6_5435589_5435798 0.25 RP1-232P20.1

22573
0.22
chr3_157250255_157250502 0.23 VEPH1
ventricular zone expressed PH domain-containing 1
1017
0.61
chr8_91895725_91895978 0.22 RP11-662G23.1

24383
0.19
chr13_50696260_50696411 0.22 DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
40028
0.15
chr3_171779467_171780048 0.22 FNDC3B
fibronectin type III domain containing 3B
15054
0.27
chr13_41576799_41576950 0.22 ELF1
E74-like factor 1 (ets domain transcription factor)
16576
0.19
chr12_12186755_12186906 0.22 BCL2L14
BCL2-like 14 (apoptosis facilitator)
15948
0.26
chr18_56245541_56245920 0.21 RP11-126O1.2

21428
0.14
chr11_124961540_124961691 0.21 TMEM218
transmembrane protein 218
11090
0.17
chr1_66258526_66259233 0.21 PDE4B
phosphodiesterase 4B, cAMP-specific
15
0.99
chr6_84139999_84140706 0.20 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
412
0.89
chr16_69213517_69213668 0.20 ENSG00000207083
.
3912
0.15
chr10_94517140_94517343 0.19 ENSG00000201412
.
46876
0.14
chr14_103589830_103590609 0.19 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
421
0.82
chr3_16006218_16006514 0.19 ENSG00000207815
.
91088
0.08
chr2_206750268_206750419 0.19 ENSG00000201875
.
15011
0.24
chr1_197113546_197113697 0.19 ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
2203
0.35
chr5_75601341_75601492 0.18 RP11-466P24.6

5871
0.31
chr7_26577801_26577952 0.18 KIAA0087
KIAA0087
531
0.86
chr6_33359684_33360329 0.18 KIFC1
kinesin family member C1
368
0.77
chr1_245019266_245019417 0.18 HNRNPU-AS1
HNRNPU antisense RNA 1
542
0.75
chr10_81007808_81008068 0.18 ZMIZ1
zinc finger, MIZ-type containing 1
58037
0.14
chr11_57529774_57530544 0.17 CTNND1
catenin (cadherin-associated protein), delta 1
869
0.5
chr1_2211042_2211193 0.17 RP4-713A8.1

47015
0.08
chr11_10627928_10628217 0.17 MRVI1-AS1
MRVI1 antisense RNA 1
13328
0.17
chr14_101292536_101293492 0.17 AL117190.2

2523
0.08
chr1_113585569_113585770 0.17 LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
30162
0.21
chrX_85249377_85249528 0.17 ENSG00000199567
.
25160
0.22
chr5_172185022_172185186 0.17 RP11-779O18.1

125
0.95
chr10_6980964_6981115 0.17 PRKCQ
protein kinase C, theta
358776
0.01
chr4_55534353_55534504 0.17 KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
10343
0.31
chr6_99426575_99426760 0.17 FBXL4
F-box and leucine-rich repeat protein 4
30818
0.24
chr2_85815578_85815729 0.16 VAMP5
vesicle-associated membrane protein 5
4122
0.1
chrX_65220138_65220337 0.16 RP6-159A1.3

644
0.75
chr7_139268726_139268877 0.16 CLEC2L
C-type lectin domain family 2, member L
59973
0.13
chrX_65222772_65222923 0.16 RP6-159A1.3

3254
0.27
chr9_755961_756198 0.16 KANK1
KN motif and ankyrin repeat domains 1
23463
0.22
chr1_167618995_167619146 0.16 RP3-455J7.4

19159
0.18
chr12_95598219_95598370 0.16 FGD6
FYVE, RhoGEF and PH domain containing 6
12861
0.18
chr4_186951313_186951505 0.15 ENSG00000222727
.
3669
0.24
chr15_52775854_52776075 0.15 MYO5A
myosin VA (heavy chain 12, myoxin)
45074
0.15
chr21_36280449_36280667 0.15 RUNX1
runt-related transcription factor 1
18471
0.28
chr5_156706927_156707078 0.15 CYFIP2
cytoplasmic FMR1 interacting protein 2
5370
0.16
chr8_31042072_31042227 0.15 RP11-363L24.3

7466
0.31
chr2_54724516_54724667 0.15 SPTBN1
spectrin, beta, non-erythrocytic 1
40193
0.15
chr15_101790171_101790322 0.15 CHSY1
chondroitin sulfate synthase 1
1891
0.31
chr17_28703666_28703850 0.15 CPD
carboxypeptidase D
2165
0.24
chr12_89889035_89889186 0.15 POC1B
POC1 centriolar protein B
1924
0.3
chr2_218806529_218806680 0.15 TNS1
tensin 1
2189
0.35
chr2_236401822_236402641 0.15 AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
502
0.83
chr1_94879075_94879226 0.15 ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
4783
0.32
chr19_42262167_42262318 0.15 CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
2913
0.18
chr4_160100922_160101459 0.14 ENSG00000264105
.
51144
0.13
chr3_112929944_112930573 0.14 BOC
BOC cell adhesion associated, oncogene regulated
71
0.98
chr5_32504728_32504940 0.14 SUB1
SUB1 homolog (S. cerevisiae)
26905
0.2
chr16_8725965_8726116 0.14 METTL22
methyltransferase like 22
8955
0.2
chr3_98609388_98609782 0.14 DCBLD2
discoidin, CUB and LCCL domain containing 2
10430
0.18
chr2_189993459_189993610 0.14 ENSG00000264725
.
4303
0.25
chr15_71148071_71148222 0.14 LARP6
La ribonucleoprotein domain family, member 6
1648
0.3
chr14_89653839_89653990 0.14 FOXN3
forkhead box N3
6826
0.3
chr19_32841958_32842109 0.14 ZNF507
zinc finger protein 507
5408
0.19
chr1_57028471_57028622 0.14 PPAP2B
phosphatidic acid phosphatase type 2B
16695
0.27
chr11_128554784_128555228 0.14 RP11-744N12.3

1317
0.34
chr7_27203057_27203424 0.14 HOXA9
homeobox A9
1905
0.11
chr3_159483400_159483608 0.14 IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
612
0.7
chr11_118435857_118436109 0.14 IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
378
0.76
chr22_50745196_50745796 0.14 PLXNB2
plexin B2
521
0.61
chr5_124078870_124079512 0.13 ZNF608
zinc finger protein 608
1023
0.42
chr4_157893196_157893594 0.13 PDGFC
platelet derived growth factor C
849
0.66
chr8_23711375_23711668 0.13 STC1
stanniocalcin 1
303
0.92
chr2_136776223_136776374 0.13 AC093391.2

6263
0.25
chr4_175750179_175750687 0.13 GLRA3
glycine receptor, alpha 3
32
0.99
chr6_138132955_138133132 0.13 RP11-356I2.4

13988
0.21
chr4_81153527_81153798 0.13 FGF5
fibroblast growth factor 5
34091
0.16
chr12_45625218_45625410 0.13 ANO6
anoctamin 6
15411
0.28
chr5_38445912_38446355 0.13 EGFLAM
EGF-like, fibronectin type III and laminin G domains
435
0.81
chr2_136631794_136631945 0.13 MCM6
minichromosome maintenance complex component 6
2127
0.3
chr1_178062269_178062757 0.13 RASAL2
RAS protein activator like 2
351
0.93
chr5_59837529_59837680 0.13 PDE4D
phosphodiesterase 4D, cAMP-specific
53701
0.16
chr2_7005603_7006667 0.13 RSAD2
radical S-adenosyl methionine domain containing 2
176
0.52
chr3_42066973_42067139 0.13 ULK4
unc-51 like kinase 4
63134
0.12
chr10_104536560_104536809 0.13 WBP1L
WW domain binding protein 1-like
678
0.63
chr1_98496294_98496445 0.12 ENSG00000225206
.
14538
0.29
chr12_91499433_91499620 0.12 LUM
lumican
6082
0.24
chr8_95563818_95563969 0.12 KIAA1429
KIAA1429
1795
0.3
chr20_57678404_57678555 0.12 SLMO2
slowmo homolog 2 (Drosophila)
60515
0.1
chr12_54652241_54652451 0.12 CBX5
chromobox homolog 5
135
0.9
chr6_33808044_33808280 0.12 MLN
motilin
36374
0.15
chr3_119349777_119349928 0.12 PLA1A
phospholipase A1 member A
22108
0.13
chr7_92258314_92258465 0.12 FAM133B
family with sequence similarity 133, member B
38681
0.16
chr12_45445409_45445593 0.12 DBX2
developing brain homeobox 2
619
0.54
chr6_105402236_105402387 0.12 LIN28B
lin-28 homolog B (C. elegans)
2612
0.35
chr21_36263531_36263991 0.12 RUNX1
runt-related transcription factor 1
1674
0.53
chr15_64671727_64672232 0.12 KIAA0101
KIAA0101
1658
0.23
chr3_106568854_106569005 0.12 ENSG00000252626
.
157486
0.04
chr8_8421576_8421727 0.12 ENSG00000263616
.
18514
0.24
chr1_52519790_52519941 0.12 TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
998
0.36
chr10_92644478_92644629 0.12 ENSG00000222305
.
4617
0.19
chr4_72159796_72159986 0.12 SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
44879
0.2
chr10_34149976_34150160 0.12 ENSG00000199200
.
340934
0.01
chr4_71940368_71940554 0.12 DCK
deoxycytidine kinase
81106
0.1
chr17_48504516_48504676 0.12 ACSF2
acyl-CoA synthetase family member 2
983
0.39
chr7_116504981_116505132 0.12 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
2402
0.29
chr3_148583159_148583310 0.12 CPA3
carboxypeptidase A3 (mast cell)
191
0.96
chr1_26158474_26158625 0.12 RP1-317E23.7

76
0.94
chr17_72869969_72870224 0.12 FDXR
ferredoxin reductase
940
0.41
chr5_52542179_52542330 0.11 MOCS2
molybdenum cofactor synthesis 2
136361
0.05
chr9_13278507_13279169 0.11 RP11-272P10.2

348
0.67
chr8_63160920_63161162 0.11 NKAIN3
Na+/K+ transporting ATPase interacting 3
460
0.91
chr3_159562165_159562360 0.11 SCHIP1
schwannomin interacting protein 1
4612
0.21
chr6_121895181_121895332 0.11 ENSG00000222659
.
6411
0.25
chr4_91239201_91239404 0.11 ENSG00000252087
.
51972
0.17
chr13_24006860_24007105 0.11 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
859
0.74
chr10_128258751_128258911 0.11 ENSG00000221717
.
13198
0.26
chr8_6603359_6603510 0.11 ENSG00000266038
.
749
0.69
chr12_93576211_93576362 0.11 RP11-511B23.2

33164
0.17
chr1_110933283_110933653 0.11 SLC16A4
solute carrier family 16, member 4
180
0.92
chr9_212362_212513 0.11 DOCK8
dedicator of cytokinesis 8
2428
0.26
chr11_33283703_33283854 0.11 HIPK3
homeodomain interacting protein kinase 3
3901
0.27
chr4_185292014_185292165 0.11 IRF2
interferon regulatory factor 2
47655
0.14
chr3_160203157_160203402 0.11 TRIM59
tripartite motif containing 59
282
0.89
chr16_73069914_73070167 0.11 ZFHX3
zinc finger homeobox 3
12234
0.21
chr5_148185821_148186248 0.11 ADRB2
adrenoceptor beta 2, surface
20122
0.24
chr14_24805236_24805387 0.11 ADCY4
adenylate cyclase 4
1034
0.21
chr5_371927_372078 0.11 AHRR
aryl-hydrocarbon receptor repressor
28359
0.15
chr2_43232535_43232725 0.11 ENSG00000207087
.
86002
0.1
chr6_51928260_51928411 0.11 ENSG00000264206
.
1831
0.37
chrX_65896718_65896962 0.11 ENSG00000222667
.
634
0.81
chr16_48647179_48647330 0.11 N4BP1
NEDD4 binding protein 1
3134
0.25
chr17_55063311_55063462 0.11 RP5-1107A17.4

3276
0.17
chr2_145278154_145278598 0.11 ZEB2-AS1
ZEB2 antisense RNA 1
203
0.55
chr8_106536977_106537128 0.11 ZFPM2
zinc finger protein, FOG family member 2
4060
0.36
chr17_76907300_76907451 0.11 CTD-2373H9.5

8030
0.14
chr19_41913570_41913729 0.11 BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
2978
0.12
chr7_30199849_30200000 0.11 AC007036.5

2777
0.24
chr11_105481715_105481968 0.11 GRIA4
glutamate receptor, ionotropic, AMPA 4
116
0.98
chr7_18376735_18376886 0.11 ENSG00000223030
.
39848
0.17
chr1_78355822_78355973 0.11 NEXN-AS1
NEXN antisense RNA 1
673
0.62
chr12_124475208_124475359 0.11 ZNF664
zinc finger protein 664
17441
0.08
chr13_113704257_113704408 0.11 MCF2L
MCF.2 cell line derived transforming sequence-like
5167
0.16
chr1_151286527_151286678 0.11 PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
12122
0.09
chr2_212025965_212026310 0.11 ENSG00000199585
.
374241
0.01
chr22_38438659_38438835 0.11 RP5-1039K5.16

8512
0.11
chr1_202474380_202474681 0.11 ENSG00000253042
.
22025
0.18
chr8_38585652_38586394 0.11 TACC1
transforming, acidic coiled-coil containing protein 1
82
0.97
chr8_16998847_16999036 0.11 ZDHHC2
zinc finger, DHHC-type containing 2
14597
0.24
chr1_115397478_115398199 0.11 SYCP1
synaptonemal complex protein 1
84
0.98
chr8_146204034_146204185 0.10 RP5-1047A19.4

14191
0.15
chr1_114525510_114525669 0.10 OLFML3
olfactomedin-like 3
2894
0.24
chr5_124079655_124079839 0.10 ZNF608
zinc finger protein 608
467
0.74
chr7_133039894_133040045 0.10 ENSG00000238844
.
92484
0.09
chr11_26305888_26306039 0.10 ANO3
anoctamin 3
25183
0.28
chr1_167518297_167518545 0.10 CREG1
cellular repressor of E1A-stimulated genes 1
4583
0.23
chr3_127453865_127454048 0.10 MGLL
monoglyceride lipase
1244
0.53
chr2_27434850_27435940 0.10 SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
5
0.66
chr17_31255277_31255844 0.10 TMEM98
transmembrane protein 98
332
0.89
chr7_27191312_27191528 0.10 HOXA-AS3
HOXA cluster antisense RNA 3
1749
0.13
chr14_55239682_55239899 0.10 SAMD4A
sterile alpha motif domain containing 4A
18239
0.24
chr16_22200871_22201892 0.10 EEF2K
eukaryotic elongation factor-2 kinase
16222
0.16
chr9_111578370_111578673 0.10 ACTL7B
actin-like 7B
40718
0.16
chr14_103316071_103316226 0.10 ENSG00000206969
.
16045
0.15
chr22_39601535_39601686 0.10 PDGFB
platelet-derived growth factor beta polypeptide
35304
0.11
chr7_12251046_12251631 0.10 TMEM106B
transmembrane protein 106B
389
0.93
chr4_156680188_156681171 0.10 GUCY1B3
guanylate cyclase 1, soluble, beta 3
68
0.98
chr20_43729394_43729952 0.10 KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
77
0.96
chr16_30770390_30770590 0.10 C16orf93
chromosome 16 open reading frame 93
555
0.55
chr15_75416074_75416396 0.10 ENSG00000252722
.
2228
0.28
chrX_149596043_149596194 0.10 MAMLD1
mastermind-like domain containing 1
6845
0.28
chr8_11415915_11416066 0.10 RP11-148O21.4

459
0.72
chr3_37114235_37114598 0.10 LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
10825
0.17
chr1_101727926_101728077 0.10 RP4-575N6.5

19287
0.16
chr11_72999273_72999424 0.10 P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
1104
0.43
chr7_106377259_106377410 0.10 CTB-111H14.1

4439
0.28
chr21_43884438_43884684 0.10 SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
31567
0.1
chr13_32518987_32519138 0.10 EEF1DP3
eukaryotic translation elongation factor 1 delta pseudogene 3
7655
0.28
chr20_2236731_2236882 0.10 TGM3
transglutaminase 3
39841
0.17
chr5_59817644_59817795 0.10 PDE4D
phosphodiesterase 4D, cAMP-specific
33816
0.22
chr12_26379869_26380400 0.10 SSPN
sarcospan
31528
0.16
chr2_64878829_64879050 0.10 SERTAD2
SERTA domain containing 2
2108
0.38
chr9_71510539_71510690 0.10 ENSG00000207000
.
40281
0.16
chr1_46017329_46017598 0.10 AKR1A1
aldo-keto reductase family 1, member A1 (aldehyde reductase)
723
0.6
chr17_40934580_40934731 0.10 WNK4
WNK lysine deficient protein kinase 4
1959
0.15
chr16_23869995_23870146 0.10 PRKCB
protein kinase C, beta
21526
0.22
chr5_180590682_180590909 0.10 OR2V2
olfactory receptor, family 2, subfamily V, member 2
8852
0.1
chr2_54649975_54650126 0.10 SPTBN1
spectrin, beta, non-erythrocytic 1
33372
0.19
chr17_27462701_27462852 0.10 MYO18A
myosin XVIIIA
4660
0.17
chr8_63998951_63999120 0.10 TTPA
tocopherol (alpha) transfer protein
423
0.86
chr7_120646497_120646648 0.10 CPED1
cadherin-like and PC-esterase domain containing 1
16896
0.19
chr12_112860746_112860897 0.10 PTPN11
protein tyrosine phosphatase, non-receptor type 11
4103
0.22
chr17_79317268_79317735 0.10 TMEM105
transmembrane protein 105
13027
0.13
chr18_56246037_56246225 0.10 ENSG00000252284
.
21732
0.14
chr20_50527044_50527195 0.10 ENSG00000252654
.
5611
0.21
chr5_95005032_95005183 0.10 SPATA9
spermatogenesis associated 9
13553
0.16
chr1_156868658_156868809 0.10 PEAR1
platelet endothelial aggregation receptor 1
5210
0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ATF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.0 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:2001280 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway