Project

ENCODE: H3K4me3 ChIP-Seq of primary human cells

Navigation

Downloads

Results for ATF6

Z-value: 1.83

Motif logo

Transcription factors associated with ATF6

Gene Symbol	Gene ID	Gene Info
ATF6 Ensembl NCBI GeneCards UniProt	ENSG00000118217.5	activating transcription factor 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_161751674_161751825	ATF6	15665	0.128357	-0.86	3.2e-03	Click!
chr1_161787074_161787225	ATF6	51065	0.096929	-0.79	1.1e-02	Click!
chr1_161736066_161736563	ATF6	230	0.558583	0.63	6.9e-02	Click!
chr1_161736570_161736834	ATF6	618	0.424659	0.37	3.3e-01	Click!
chr1_161806160_161806311	ATF6	70151	0.076946	-0.36	3.4e-01	Click!

Activity of the ATF6 motif across conditions

Conditions sorted by the z-value of the ATF6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrY_1604612_1604993	2.29	NA	NA	> 10⁶	NA
chrX_1654663_1654996	2.21	P2RY8	purinergic receptor P2Y, G-protein coupled, 8	1171	0.53
chr20_47435468_47435675	1.35	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	8849	0.27
chr1_26872331_26872899	1.33	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	272	0.88
chr9_132649272_132649423	1.28	FNBP1	formin binding protein 1	32242	0.13
chr15_81589062_81589213	1.27	IL16	interleukin 16	117	0.97
chr14_24607151_24607302	1.18	PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	1790	0.12
chr12_15110903_15111342	1.17	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	3078	0.22
chr2_32981233_32981524	1.16	TTC27	tetratricopeptide repeat domain 27	77433	0.11
chrY_1730731_1731007	1.12	ENSG00000251841	.	921921	0.0
chrX_1780732_1781004	1.11	ASMT	acetylserotonin O-methyltransferase	25577	0.22
chr17_61775506_61775979	1.08	LIMD2	LIM domain containing 2	780	0.58
chr6_170403243_170403627	1.02	RP11-302L19.1		74306	0.11
chr15_38850304_38850496	1.01	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	1883	0.34
chr9_130726612_130726763	0.99	FAM102A	family with sequence similarity 102, member A	13686	0.1
chr8_28918430_28918927	0.97	CTD-2647L4.4		5226	0.15
chr9_92111480_92111784	0.97	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	715	0.59
chr6_24933928_24934155	0.94	FAM65B	family with sequence similarity 65, member B	2147	0.37
chr5_171601000_171601151	0.93	STK10	serine/threonine kinase 10	14315	0.19
chr12_122230087_122230336	0.91	RHOF	ras homolog family member F (in filopodia)	1055	0.48
chr19_35531341_35531561	0.90	HPN	hepsin	41	0.95
chr5_169723906_169724096	0.89	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	1230	0.52
chr4_40199529_40199726	0.89	RHOH	ras homolog family member H	1100	0.55
chr14_22945029_22945180	0.88	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	192	0.89
chrX_122993811_122994132	0.87	XIAP	X-linked inhibitor of apoptosis	94	0.96
chr5_66460452_66460675	0.86	MAST4	microtubule associated serine/threonine kinase family member 4	22301	0.23
chr7_50727728_50727879	0.86	GRB10	growth factor receptor-bound protein 10	33176	0.21
chr3_193973103_193973434	0.85	CPN2	carboxypeptidase N, polypeptide 2	98779	0.06
chr19_6772910_6773160	0.84	VAV1	vav 1 guanine nucleotide exchange factor	66	0.96
chr4_154443229_154443447	0.83	KIAA0922	KIAA0922	33710	0.2
chr13_111358644_111359052	0.81	CARS2	cysteinyl-tRNA synthetase 2, mitochondrial (putative)	344	0.89
chr1_12235343_12235565	0.80	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	8394	0.16
chr1_110045467_110045747	0.78	AMIGO1	adhesion molecule with Ig-like domain 1	6697	0.11
chr1_234746129_234746973	0.78	IRF2BP2	interferon regulatory factor 2 binding protein 2	1280	0.44
chr6_32159695_32160229	0.77	GPSM3	G-protein signaling modulator 3	683	0.42
chr20_55967619_55967903	0.75	RP4-800J21.3		357	0.56
chr11_68596728_68596879	0.75	CPT1A	carnitine palmitoyltransferase 1A (liver)	10349	0.2
chr1_235468614_235468765	0.75	GGPS1	geranylgeranyl diphosphate synthase 1	21976	0.17
chr10_45958590_45958741	0.74	RP11-67C2.2		10096	0.25
chr19_15575302_15575574	0.74	RASAL3	RAS protein activator like 3	56	0.96
chr22_50987791_50988003	0.73	KLHDC7B	kelch domain containing 7B	1435	0.18
chr1_151445466_151445952	0.73	POGZ	pogo transposable element with ZNF domain	13768	0.11
chr3_38179539_38180050	0.72	MYD88	myeloid differentiation primary response 88	175	0.89
chr14_22946001_22946152	0.72	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	780	0.46
chrX_134478382_134478635	0.72	ZNF449	zinc finger protein 449	213	0.76
chr10_81678709_81678860	0.72	SFTPD	surfactant protein D	30075	0.2
chr11_117101029_117101180	0.71	PCSK7	proprotein convertase subtilisin/kexin type 7	148	0.93
chr7_6522650_6523366	0.71	FLJ20306	CDNA FLJ20306 fis, clone HEP06881; Putative uncharacterized protein FLJ20306; Uncharacterized protein	86	0.87
chr1_39500021_39500217	0.71	NDUFS5	NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)	8129	0.18
chr6_30583732_30584317	0.71	ENSG00000222894	.	58	0.9
chr5_53987595_53987746	0.70	ENSG00000221073	.	161106	0.04
chr1_9713063_9713437	0.69	C1orf200	chromosome 1 open reading frame 200	1394	0.31
chr3_45152218_45152388	0.69	CDCP1	CUB domain containing protein 1	35611	0.16
chr10_126916601_126916752	0.68	CTBP2	C-terminal binding protein 2	67046	0.13
chr16_3116517_3116777	0.68	IL32	interleukin 32	834	0.3
chr10_129860638_129860789	0.67	PTPRE	protein tyrosine phosphatase, receptor type, E	14879	0.26
chr2_240186620_240186969	0.67	ENSG00000265215	.	40363	0.13
chr2_28615100_28615446	0.67	FOSL2	FOS-like antigen 2	396	0.81
chr14_93123743_93123904	0.65	RIN3	Ras and Rab interactor 3	4977	0.3
chr13_52395252_52395592	0.65	RP11-327P2.5		16989	0.18
chr13_114896019_114896170	0.65	RASA3	RAS p21 protein activator 3	1933	0.38
chr19_4916483_4916936	0.64	ARRDC5	arrestin domain containing 5	13830	0.12
chr3_50647630_50647785	0.64	CISH	cytokine inducible SH2-containing protein	1496	0.28
chr1_16543271_16543460	0.64	ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19	4261	0.12
chrX_49117374_49117525	0.63	FOXP3	forkhead box P3	1752	0.19
chr9_130667567_130667722	0.63	ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	35	0.94
chr17_266453_266873	0.63	AC108004.3		2849	0.2
chr9_116280364_116280637	0.62	RGS3	regulator of G-protein signaling 3	950	0.63
chr7_150216886_150217185	0.62	GIMAP7	GTPase, IMAP family member 7	5117	0.21
chr15_93446819_93447199	0.61	ENSG00000264173	.	620	0.48
chr5_1668871_1669022	0.61	RP11-43F13.1		34925	0.15
chr17_76776046_76776325	0.61	CYTH1	cytohesin 1	2169	0.3
chr7_128378913_128379302	0.61	CALU	calumenin	239	0.88
chr3_196365832_196366436	0.61	NRROS	negative regulator of reactive oxygen species	423	0.51
chr8_22398297_22398465	0.60	RP11-582J16.4		4537	0.13
chr6_144655565_144656031	0.60	RP1-91J24.3		1361	0.51
chr20_3451275_3451544	0.60	ATRN	attractin	278	0.91
chr5_157285819_157286122	0.60	CLINT1	clathrin interactor 1	171	0.96
chr12_64797769_64798005	0.59	XPOT	exportin, tRNA	243	0.92
chr17_75371888_75372374	0.59	SEPT9	septin 9	34	0.96
chr22_40297430_40297673	0.59	GRAP2	GRB2-related adaptor protein 2	438	0.81
chr12_15114594_15114745	0.59	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	7	0.97
chr17_38476195_38476719	0.59	RARA	retinoic acid receptor, alpha	1920	0.22
chr14_97925575_97925808	0.58	ENSG00000240730	.	70819	0.14
chr12_6554644_6554853	0.58	CD27	CD27 molecule	715	0.48
chr14_71122204_71122420	0.58	TTC9	tetratricopeptide repeat domain 9	13808	0.21
chr3_194118884_194119077	0.58	GP5	glycoprotein V (platelet)	103	0.96
chr7_65235868_65236176	0.58	ENSG00000206785	.	10983	0.15
chr17_36665851_36666234	0.57	ARHGAP23	Rho GTPase activating protein 23	12007	0.17
chr9_137347969_137348661	0.57	RXRA	retinoid X receptor, alpha	49887	0.15
chr2_99225208_99225370	0.57	UNC50	unc-50 homolog (C. elegans)	18	0.83
chr12_46777496_46777801	0.57	SLC38A2	solute carrier family 38, member 2	10998	0.24
chr16_88812277_88812428	0.56	RP5-1142A6.8		3123	0.11
chrY_15590049_15590474	0.56	UTY	ubiquitously transcribed tetratricopeptide repeat containing, Y-linked	1284	0.62
chr10_124134278_124134675	0.56	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	126	0.96
chr20_24008090_24008393	0.56	GGTLC1	gamma-glutamyltransferase light chain 1	38825	0.2
chr19_36233477_36233815	0.55	IGFLR1	IGF-like family receptor 1	292	0.71
chr2_64369947_64371114	0.55	AC074289.1		157	0.93
chr16_88658218_88658369	0.55	ZC3H18	zinc finger CCCH-type containing 18	5268	0.15
chr17_75450125_75450790	0.54	SEPT9	septin 9	295	0.88
chr14_105530971_105531214	0.54	GPR132	G protein-coupled receptor 132	675	0.7
chr3_177040689_177040840	0.54	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	125503	0.06
chr7_73509063_73509569	0.54	LIMK1	LIM domain kinase 1	1907	0.33
chr2_152685132_152685445	0.54	ARL5A	ADP-ribosylation factor-like 5A	286	0.95
chr11_66725931_66726082	0.53	PC	pyruvate carboxylase	159	0.93
chr8_70042166_70042317	0.53	ENSG00000238808	.	19432	0.3
chrX_118823299_118823461	0.53	SEPT6	septin 6	3412	0.23
chr3_13460524_13460714	0.53	NUP210	nucleoporin 210kDa	1190	0.56
chr16_53553189_53553344	0.53	AKTIP	AKT interacting protein	14943	0.21
chr2_235361916_235362359	0.53	ARL4C	ADP-ribosylation factor-like 4C	43107	0.21
chr11_127906486_127906637	0.52	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	468728	0.01
chr11_1911215_1911366	0.52	C11orf89	chromosome 11 open reading frame 89	794	0.46
chrX_153191913_153192277	0.51	ARHGAP4	Rho GTPase activating protein 4	116	0.92
chr4_8160776_8160952	0.51	ABLIM2	actin binding LIM protein family, member 2	305	0.91
chr14_90147435_90147962	0.51	ENSG00000252655	.	30451	0.14
chr17_66082289_66082451	0.51	LINC00674	long intergenic non-protein coding RNA 674	15679	0.18
chr9_38621823_38622122	0.51	FAM201A	family with sequence similarity 201, member A	887	0.5
chr2_211287199_211287350	0.51	LANCL1	LanC lantibiotic synthetase component C-like 1 (bacterial)	18195	0.2
chr6_149803641_149803913	0.51	ZC3H12D	zinc finger CCCH-type containing 12D	492	0.77
chr1_33565203_33565487	0.51	ADC	arginine decarboxylase	17494	0.18
chr6_157932056_157932271	0.50	ENSG00000266617	.	18001	0.26
chr16_81503309_81503531	0.50	CMIP	c-Maf inducing protein	24645	0.23
chr2_201987300_201987657	0.50	CFLAR	CASP8 and FADD-like apoptosis regulator	278	0.87
chr7_5571391_5571891	0.50	ACTB	actin, beta	1301	0.32
chr16_68320292_68320685	0.50	ENSG00000252026	.	2267	0.13
chr21_43824958_43825228	0.50	UBASH3A	ubiquitin associated and SH3 domain containing A	1067	0.41
chrX_128915626_128915992	0.50	SASH3	SAM and SH3 domain containing 3	1849	0.35
chr20_827831_828145	0.50	FAM110A	family with sequence similarity 110, member A	2221	0.36
chrX_100872700_100873033	0.50	ARMCX6	armadillo repeat containing, X-linked 6	125	0.93
chr9_80850783_80850986	0.49	CEP78	centrosomal protein 78kDa	94	0.98
chr7_963478_963629	0.49	ADAP1	ArfGAP with dual PH domains 1	3027	0.2
chr17_6555060_6555332	0.49	C17orf100	chromosome 17 open reading frame 100	225	0.49
chr22_18111003_18111464	0.49	ATP6V1E1	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	266	0.66
chr15_60868144_60868295	0.49	RORA	RAR-related orphan receptor A	16521	0.2
chr17_80564167_80564318	0.49	RP13-638C3.4		2188	0.18
chr19_8942638_8942914	0.49	ZNF558	zinc finger protein 558	228	0.54
chr18_21592213_21592364	0.48	TTC39C	tetratricopeptide repeat domain 39C	2096	0.28
chr7_37797263_37797414	0.48	GPR141	G protein-coupled receptor 141	17342	0.25
chr3_128399436_128399670	0.48	RPN1	ribophorin I	365	0.87
chr2_70321532_70321889	0.48	PCBP1-AS1	PCBP1 antisense RNA 1	5732	0.17
chr1_161186326_161186719	0.48	FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	1435	0.17
chr16_374610_374868	0.48	AXIN1	axin 1	27710	0.08
chr1_225611644_225611795	0.48	LBR	lamin B receptor	3880	0.22
chr17_63053075_63053367	0.48	GNA13	guanine nucleotide binding protein (G protein), alpha 13	264	0.91
chr3_13056943_13057225	0.47	IQSEC1	IQ motif and Sec7 domain 1	28548	0.23
chr1_33816075_33816314	0.47	RP11-415J8.5		241	0.78
chr2_85765868_85766150	0.47	MAT2A	methionine adenosyltransferase II, alpha	279	0.82
chr6_158981534_158982064	0.47	TMEM181	transmembrane protein 181	24331	0.19
chr22_29168515_29168886	0.47	CCDC117	coiled-coil domain containing 117	16	0.97
chr3_27674016_27674276	0.47	ENSG00000238912	.	84797	0.09
chr17_75877482_75877763	0.47	FLJ45079		1037	0.6
chr13_50698385_50698672	0.47	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	42221	0.15
chr14_52329027_52329412	0.47	GNG2	guanine nucleotide binding protein (G protein), gamma 2	1177	0.52
chr20_48297399_48297550	0.47	B4GALT5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	32941	0.15
chr20_62271866_62272113	0.47	STMN3	stathmin-like 3	12130	0.09
chr11_118763744_118763895	0.46	RP11-158I9.5		5368	0.1
chr19_1068460_1068611	0.46	HMHA1	histocompatibility (minor) HA-1	1038	0.32
chr17_75453810_75454179	0.46	SEPT9	septin 9	1546	0.33
chr1_153513907_153514058	0.46	S100A5	S100 calcium binding protein A5	259	0.81
chr22_44392571_44392722	0.46	PARVB	parvin, beta	2445	0.31
chr5_162931423_162932027	0.46	MAT2B	methionine adenosyltransferase II, beta	829	0.58
chr20_36825206_36825357	0.45	TGM2	transglutaminase 2	30301	0.14
chr22_37696666_37696924	0.45	CYTH4	cytohesin 4	9214	0.17
chrX_129220262_129220541	0.45	ELF4	E74-like factor 4 (ets domain transcription factor)	23935	0.18
chr13_41557045_41557196	0.45	ELF1	E74-like factor 1 (ets domain transcription factor)	702	0.71
chr17_5485043_5485194	0.45	NLRP1	NLR family, pyrin domain containing 1	2159	0.34
chr13_103425733_103426013	0.45	TEX30	testis expressed 30	232	0.89
chr2_102613475_102613626	0.45	IL1R2	interleukin 1 receptor, type II	1907	0.43
chr12_57030254_57030540	0.45	BAZ2A	bromodomain adjacent to zinc finger domain, 2A	234	0.88
chr19_12903527_12903836	0.45	JUNB	jun B proto-oncogene	1371	0.18
chr12_54610003_54610573	0.45	ENSG00000265371	.	14972	0.1
chrX_39796396_39796688	0.45	ENSG00000263972	.	99727	0.08
chr2_120934672_120935030	0.45	ENSG00000202046	.	14970	0.19
chr20_4707737_4707988	0.45	PRND	prion protein 2 (dublet)	5306	0.21
chr17_73400270_73401657	0.45	GRB2	growth factor receptor-bound protein 2	604	0.48
chr20_61641850_61642001	0.45	BHLHE23	basic helix-loop-helix family, member e23	3538	0.23
chr13_114893960_114894535	0.44	RASA3	RAS p21 protein activator 3	3780	0.26
chr1_25891436_25891587	0.44	LDLRAP1	low density lipoprotein receptor adaptor protein 1	21440	0.18
chr11_64648039_64648569	0.44	EHD1	EH-domain containing 1	1132	0.31
chr9_123833984_123834761	0.44	CNTRL	centriolin	2769	0.29
chr12_105035462_105035613	0.44	ENSG00000264295	.	50126	0.15
chr1_231113322_231113566	0.44	TTC13	tetratricopeptide repeat domain 13	1098	0.34
chr3_187457028_187457694	0.44	BCL6	B-cell CLL/lymphoma 6	1629	0.41
chr16_15737211_15737772	0.43	ENSG00000272213	.	340	0.38
chr15_74988471_74988935	0.43	EDC3	enhancer of mRNA decapping 3	70	0.97
chr2_238581872_238582461	0.43	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	18622	0.2
chr2_170221171_170221397	0.43	LRP2	low density lipoprotein receptor-related protein 2	2089	0.42
chr7_158936828_158937151	0.43	VIPR2	vasoactive intestinal peptide receptor 2	555	0.87
chrX_57936443_57936703	0.43	ZXDA	zinc finger, X-linked, duplicated A	494	0.9
chr8_109455244_109455634	0.43	EMC2	ER membrane protein complex subunit 2	391	0.92
chr19_41931347_41931498	0.43	CTC-435M10.6		158	0.89
chr2_60597080_60597231	0.42	ENSG00000200807	.	14585	0.22
chr11_67172347_67172531	0.42	TBC1D10C	TBC1 domain family, member 10C	779	0.35
chr22_25574963_25575316	0.42	CRYBB3	crystallin, beta B3	20678	0.19
chr3_186730669_186730826	0.42	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	8896	0.24
chr5_110866025_110866435	0.42	STARD4	StAR-related lipid transfer (START) domain containing 4	17942	0.18
chr16_84401582_84401733	0.42	ATP2C2	ATPase, Ca++ transporting, type 2C, member 2	476	0.82
chr4_57843452_57843737	0.42	POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	294	0.84
chr9_71394333_71394801	0.42	FAM122A	family with sequence similarity 122A	397	0.88
chr7_130791022_130791700	0.42	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	428	0.85

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	0.9	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2	0.5	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.2	0.5	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.4	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.5	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.5	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.1	0.3	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	1.4	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.1	0.3	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.1	0.4	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1	0.6	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.3	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.1	0.3	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.1	0.3	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.1	0.3	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.3	GO:0033131	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.1	0.4	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.1	0.3	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.2	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1	0.3	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1	0.4	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.1	0.6	GO:0042119	neutrophil activation(GO:0042119)
0.1	0.2	GO:0031062	positive regulation of histone methylation(GO:0031062) positive regulation of histone H3-K4 methylation(GO:0051571)
0.1	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.1	0.4	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.4	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.1	0.2	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.4	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	0.3	GO:0002363	alpha-beta T cell lineage commitment(GO:0002363)
0.1	0.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.5	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.1	0.5	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.1	0.1	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1	0.5	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.2	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.4	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.1	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1	0.6	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.1	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.5	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.6	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.3	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.1	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1	0.3	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.1	0.2	GO:0001866	NK T cell proliferation(GO:0001866)
0.1	0.5	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.4	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.1	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.3	GO:0006545	glycine biosynthetic process(GO:0006545)
0.1	0.2	GO:0045006	DNA deamination(GO:0045006)
0.1	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.3	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.1	0.2	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.1	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.2	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.1	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.4	GO:0045116	protein neddylation(GO:0045116)
0.1	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.3	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.5	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.3	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.2	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.2	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.2	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.0	GO:0043368	positive T cell selection(GO:0043368)
0.0	2.7	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
0.0	0.3	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.2	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0016577	histone demethylation(GO:0016577)
0.0	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.2	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.6	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.3	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.3	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.2	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.2	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.3	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.0	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.3	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	1.0	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.4	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.5	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.4	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.4	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.2	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.2	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.4	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.2	GO:0051642	centrosome localization(GO:0051642)
0.0	0.2	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.2	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.2	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.1	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.2	GO:0048291	isotype switching to IgG isotypes(GO:0048291)
0.0	0.1	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.3	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.1	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.2	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.2	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.4	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0033235	regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.6	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.2	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.0	GO:0043247	telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.2	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.6	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	1.1	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:1904019	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.3	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.1	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.1	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.7	GO:0016236	macroautophagy(GO:0016236)
0.0	0.1	GO:0051293	establishment of spindle localization(GO:0051293) spindle localization(GO:0051653)
0.0	0.1	GO:2000399	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.2	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.4	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.0	GO:1904748	regulation of apoptotic process involved in morphogenesis(GO:1902337) regulation of apoptotic process involved in development(GO:1904748)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0055026	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.4	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0	0.3	GO:0044766	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.3	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.0	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	3.3	GO:0006184	obsolete GTP catabolic process(GO:0006184)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	1.3	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.4	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.2	GO:0034033	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.2	GO:0010171	body morphogenesis(GO:0010171)
0.0	0.0	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.2	GO:0001881	receptor recycling(GO:0001881)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.0	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.4	GO:1990778	protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.3	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.2	GO:0006901	vesicle coating(GO:0006901) single-organism membrane budding(GO:1902591)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.4	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0002885	positive regulation of hypersensitivity(GO:0002885)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.2	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.4	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.4	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0032329	serine transport(GO:0032329)
0.0	0.0	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	1.6	GO:0050657	nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	1.1	GO:0051352	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0	0.1	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.2	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.9	GO:0097193	intrinsic apoptotic signaling pathway(GO:0097193)
0.0	0.3	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.3	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	1.0	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	1.5	GO:0097190	apoptotic signaling pathway(GO:0097190)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0033032	regulation of myeloid cell apoptotic process(GO:0033032)
0.0	0.3	GO:0031055	chromatin remodeling at centromere(GO:0031055)
0.0	0.4	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.1	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.2	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.2	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.1	GO:0051593	response to folic acid(GO:0051593)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.1	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.0	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.0	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.0	0.6	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0030540	female genitalia development(GO:0030540)
0.0	0.1	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.0	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.0	GO:0006525	arginine metabolic process(GO:0006525)
0.0	0.5	GO:0030217	T cell differentiation(GO:0030217)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.2	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0021554	optic nerve development(GO:0021554)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.0	GO:0002577	regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579) positive regulation of dendritic cell antigen processing and presentation(GO:0002606) interleukin-3 production(GO:0032632)
0.0	0.0	GO:0051709	regulation of killing of cells of other organism(GO:0051709)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.0	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.0	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.0	0.4	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	1.1	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.0	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.7	GO:0043039	tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0	0.1	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.0	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.3	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.2	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.0	GO:0008216	spermidine metabolic process(GO:0008216) spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.0	0.0	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.5	GO:0000236	mitotic prometaphase(GO:0000236)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.2	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0032613	interleukin-10 production(GO:0032613)
0.0	0.0	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.0	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0	0.0	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	1.7	GO:0000375	RNA splicing, via transesterification reactions(GO:0000375)
0.0	0.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.0	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.1	GO:0010506	regulation of autophagy(GO:0010506)
0.0	0.1	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.6	GO:0030048	actin filament-based movement(GO:0030048)
0.0	0.1	GO:0015793	glycerol transport(GO:0015793)
0.0	0.0	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0043526	obsolete neuroprotection(GO:0043526)
0.0	0.1	GO:0030307	positive regulation of cell growth(GO:0030307)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0009065	glutamine family amino acid catabolic process(GO:0009065)
0.0	0.0	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.0	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.0	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.6	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.0	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0000239	pachytene(GO:0000239)
0.0	0.4	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	1.7	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.0	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.1	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.4	GO:0046777	protein autophosphorylation(GO:0046777)
0.0	0.0	GO:2001252	positive regulation of chromosome organization(GO:2001252)
0.0	0.1	GO:1902099	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:0009249	protein lipoylation(GO:0009249)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.4	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	0.4	GO:0072487	MSL complex(GO:0072487)
0.1	0.5	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.4	GO:0008537	proteasome activator complex(GO:0008537)
0.1	0.3	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.4	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.5	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	0.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.3	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	0.4	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.1	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.2	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.1	0.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.3	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.5	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.1	0.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	0.3	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.2	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1	1.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	2.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.3	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.4	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.2	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.2	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.4	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	2.6	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.5	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.3	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.3	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.6	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	1.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.3	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0000792	heterochromatin(GO:0000792)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.5	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.8	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.0	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.8	GO:0042641	actomyosin(GO:0042641)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	2.3	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.7	GO:0005814	centriole(GO:0005814)
0.0	0.2	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.0	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.7	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.1	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.6	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.3	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.7	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	1.4	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.3	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.3	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.7	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0	0.1	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.1	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.3	GO:0031514	motile cilium(GO:0031514)
0.0	1.2	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.2	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.0	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.5	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.2	GO:0032420	stereocilium(GO:0032420)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	2.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.9	GO:0005813	centrosome(GO:0005813)
0.0	0.2	GO:0000922	spindle pole(GO:0000922)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.0	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
0.0	0.2	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.5	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	15.5	GO:0005829	cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	0.5	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	2.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.7	GO:0009374	biotin binding(GO:0009374)
0.1	0.4	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.6	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.3	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	0.3	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.3	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.3	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.3	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.4	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.5	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.8	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.3	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	0.4	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.1	0.3	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.1	0.2	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.8	GO:0005123	death receptor binding(GO:0005123)
0.1	0.2	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.3	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.2	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.3	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.5	GO:0005536	glucose binding(GO:0005536)
0.1	0.7	GO:0030276	clathrin binding(GO:0030276)
0.1	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	1.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.1	0.5	GO:0001671	ATPase activator activity(GO:0001671)
0.1	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.8	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	0.4	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.6	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.4	GO:0008172	S-methyltransferase activity(GO:0008172)
0.1	0.2	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.2	GO:0031404	chloride ion binding(GO:0031404)
0.1	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.1	0.3	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.2	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	1.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.2	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.2	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.4	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.3	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.7	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.4	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	1.1	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0019956	chemokine binding(GO:0019956)
0.0	0.2	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.2	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.6	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.6	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.4	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.7	GO:0000049	tRNA binding(GO:0000049)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.3	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	1.2	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.6	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	1.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.3	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.4	GO:0043621	protein self-association(GO:0043621)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.5	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.6	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.4	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	1.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.3	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.2	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.8	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.7	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0017136	NAD-dependent histone deacetylase activity(GO:0017136)
0.0	3.2	GO:0003924	GTPase activity(GO:0003924)
0.0	0.8	GO:0005507	copper ion binding(GO:0005507)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.4	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.7	GO:0050136	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.5	GO:0036459	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	2.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.6	GO:0051536	iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.0	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.5	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	1.1	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.2	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.4	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.2	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.2	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.2	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.3	GO:0050661	NADP binding(GO:0050661)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.8	GO:0031072	heat shock protein binding(GO:0031072)
0.0	1.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.2	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0005343	organic acid:sodium symporter activity(GO:0005343)
0.0	0.6	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.0	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0043495	protein anchor(GO:0043495)
0.0	1.3	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	2.1	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	1.4	GO:0005525	GTP binding(GO:0005525)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.0	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0015250	water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	1.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	0.6	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	1.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	0.6	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	0.8	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	1.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	2.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.7	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.9	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	1.2	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.3	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.6	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	PID ATM PATHWAY	ATM pathway
0.0	0.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.2	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.0	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.6	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	0.6	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.5	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	0.9	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	0.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1	1.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.6	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	1.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	1.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.9	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.0	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.0	1.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.0	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.0	REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	Genes involved in Signaling by TGF-beta Receptor Complex
0.0	0.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.5	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	2.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	1.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.9	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	2.0	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.7	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.0	REACTOME KINESINS	Genes involved in Kinesins

Results for ATF6

Z-value: 1.83

Motif logo

Transcription factors associated with ATF6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ATF6 motif across conditions

Conditions sorted by the z-value of the ATF6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: