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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for BACH1_NFE2_NFE2L2

Z-value: 2.46

Motif logo

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol Gene ID Gene Info
ENSG00000156273.11 BACH1
ENSG00000123405.9 NFE2
ENSG00000116044.11 NFE2L2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
BACH1chr21_30689027_30689178103480.1825480.771.5e-02Click!
BACH1chr21_30688725_30688876106500.1820870.732.4e-02Click!
BACH1chr21_30687972_30688123105230.1829600.703.7e-02Click!
BACH1chr21_30620619_30620770504980.1001380.646.1e-02Click!
BACH1chr21_30677925_306781034900.8090350.618.1e-02Click!
NFE2chr12_54690613_546908979130.3315530.933.2e-04Click!
NFE2chr12_54688592_546889427750.3968510.924.3e-04Click!
NFE2chr12_54689177_546893282900.7753540.924.5e-04Click!
NFE2chr12_54689023_546891744440.6319820.909.1e-04Click!
NFE2chr12_54693479_5469363512420.2106550.818.6e-03Click!
NFE2L2chr2_178127025_1781278197600.459348-0.655.8e-02Click!
NFE2L2chr2_178125992_17812625620580.186804-0.481.9e-01Click!
NFE2L2chr2_178104885_17810523578450.1113070.462.2e-01Click!
NFE2L2chr2_178125001_17812567128460.149705-0.363.5e-01Click!
NFE2L2chr2_178140372_178140777107150.1075060.353.5e-01Click!

Activity of the BACH1_NFE2_NFE2L2 motif across conditions

Conditions sorted by the z-value of the BACH1_NFE2_NFE2L2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_233249017_233249707 1.56 PCNXL2
pecanex-like 2 (Drosophila)
46691
0.19
chr10_6443642_6443853 1.24 DKFZP667F0711

51469
0.16
chr19_33784339_33784950 1.16 CTD-2540B15.11

6196
0.14
chr18_47003399_47003645 1.15 RP11-110H1.4

8997
0.09
chr22_47149775_47150260 1.06 CTA-29F11.1

8443
0.18
chr6_147197427_147197865 1.06 STXBP5-AS1
STXBP5 antisense RNA 1
25505
0.25
chr2_111751565_111751824 1.05 ACOXL
acyl-CoA oxidase-like
6919
0.31
chr19_10923780_10924057 1.03 ENSG00000207752
.
4254
0.14
chr1_10475436_10475736 1.03 APITD1
apoptosis-inducing, TAF9-like domain 1
14573
0.1
chr7_115670709_115671033 1.03 TFEC
transcription factor EC
4
0.99
chr17_74442541_74443075 1.02 UBE2O
ubiquitin-conjugating enzyme E2O
6480
0.12
chr9_127520724_127520937 0.98 RP11-175D17.3

11572
0.14
chr11_72446771_72446922 0.97 ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
8673
0.12
chr15_59836085_59836236 0.91 ENSG00000201704
.
30261
0.14
chr18_74189003_74189166 0.89 ZNF516
zinc finger protein 516
13651
0.17
chr8_101231400_101231551 0.89 ENSG00000199667
.
34109
0.13
chr1_42175219_42175489 0.86 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
8682
0.27
chr8_52782524_52782885 0.86 PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
24399
0.15
chr3_152094299_152094568 0.85 TMEM14E
transmembrane protein 14E
35654
0.17
chr14_35843711_35843965 0.85 NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
29508
0.2
chr17_79133489_79133672 0.85 AATK-AS1
AATK antisense RNA 1
5727
0.1
chr4_15659797_15659948 0.84 FBXL5
F-box and leucine-rich repeat protein 5
1615
0.4
chr6_14734934_14735085 0.83 ENSG00000206960
.
88243
0.1
chr17_65427494_65427948 0.83 ENSG00000201547
.
22724
0.12
chr1_17634731_17635053 0.80 PADI4
peptidyl arginine deiminase, type IV
200
0.93
chr12_48170565_48170736 0.79 SLC48A1
solute carrier family 48 (heme transporter), member 1
3659
0.16
chr2_10425679_10425865 0.78 ENSG00000264030
.
5015
0.19
chr15_80452796_80453143 0.77 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
4676
0.25
chr4_105982370_105982725 0.76 ENSG00000252136
.
44597
0.16
chr8_132828485_132828822 0.75 EFR3A
EFR3 homolog A (S. cerevisiae)
87682
0.1
chr19_49467193_49467878 0.75 FTL
ferritin, light polypeptide
1023
0.28
chr16_12910185_12910336 0.75 CPPED1
calcineurin-like phosphoesterase domain containing 1
12386
0.18
chr19_16567801_16568854 0.74 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
14427
0.12
chr5_57555667_57556212 0.74 ENSG00000238899
.
189924
0.03
chr11_5618695_5618968 0.73 TRIM6
tripartite motif containing 6
795
0.34
chr15_91459213_91459364 0.73 MAN2A2
mannosidase, alpha, class 2A, member 2
3170
0.11
chr15_58624481_58624632 0.72 ALDH1A2
aldehyde dehydrogenase 1 family, member A2
53094
0.15
chr16_1992022_1992173 0.71 MSRB1
methionine sulfoxide reductase B1
1027
0.22
chr16_21623104_21623255 0.71 METTL9
methyltransferase like 9
242
0.89
chr1_43407500_43407651 0.71 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
10779
0.18
chr17_441417_441568 0.71 RP5-1029F21.2

14314
0.17
chr17_6757690_6757943 0.69 TEKT1
tektin 1
22736
0.14
chr16_31881606_31881883 0.69 ZNF267
zinc finger protein 267
3335
0.29
chr5_171279662_171279813 0.68 SMIM23
small integral membrane protein 23
66847
0.11
chr2_208104248_208104487 0.68 AC007879.5

14609
0.21
chr8_26123485_26124097 0.67 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
25216
0.23
chr6_34253179_34253351 0.67 C6orf1
chromosome 6 open reading frame 1
36018
0.16
chr17_80175660_80175811 0.66 RP13-516M14.2

3632
0.13
chr16_18815542_18815693 0.65 RP11-1035H13.2

1212
0.34
chr8_56814335_56814486 0.65 ENSG00000199405
.
1004
0.46
chr7_1570565_1570716 0.64 MAFK
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
290
0.87
chr12_56075239_56075869 0.64 METTL7B
methyltransferase like 7B
224
0.86
chr21_19157038_19157189 0.64 AL109761.5

8692
0.24
chr3_187491731_187491915 0.64 BCL6
B-cell CLL/lymphoma 6
28308
0.2
chr1_56982304_56982688 0.63 PPAP2B
phosphatidic acid phosphatase type 2B
62745
0.14
chr20_1550154_1550305 0.63 SIRPB1
signal-regulatory protein beta 1
2329
0.22
chr16_28607764_28607915 0.63 SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
38
0.96
chrX_109330942_109331348 0.62 ENSG00000265584
.
5799
0.25
chr6_13273500_13273733 0.62 PHACTR1
phosphatase and actin regulator 1
627
0.46
chr15_94779920_94780071 0.62 MCTP2
multiple C2 domains, transmembrane 2
5228
0.35
chr7_44678436_44678587 0.62 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
14450
0.18
chr10_115604050_115604207 0.62 DCLRE1A
DNA cross-link repair 1A
9731
0.17
chr9_136710503_136710686 0.62 SARDH
sarcosine dehydrogenase
105517
0.06
chr6_34632212_34632529 0.62 C6orf106
chromosome 6 open reading frame 106
7363
0.14
chr12_124252082_124252425 0.61 DNAH10
dynein, axonemal, heavy chain 10
5211
0.19
chr7_36636829_36636980 0.61 AOAH
acyloxyacyl hydrolase (neutrophil)
2642
0.26
chr15_90420057_90420208 0.61 ENSG00000264796
.
7130
0.11
chr19_8307301_8307493 0.60 CTD-3020H12.4

2865
0.2
chr7_1553073_1553492 0.59 AC102953.6

4219
0.16
chr8_131012205_131012356 0.59 ENSG00000253043
.
4567
0.2
chr5_177904286_177904437 0.59 CTB-26E19.1

34266
0.18
chr5_150439543_150439694 0.59 TNIP1
TNFAIP3 interacting protein 1
5038
0.22
chr1_221219794_221220024 0.59 HLX
H2.0-like homeobox
165325
0.04
chr2_160711950_160712101 0.58 LY75
lymphocyte antigen 75
49168
0.13
chr16_88367140_88367361 0.58 ZNF469
zinc finger protein 469
126629
0.05
chr6_133069776_133069927 0.58 RP1-55C23.7

3963
0.15
chr5_39270484_39270720 0.58 FYB
FYN binding protein
144
0.98
chr13_78659821_78660303 0.57 RNF219-AS1
RNF219 antisense RNA 1
30772
0.24
chr12_51720692_51720843 0.57 BIN2
bridging integrator 2
2315
0.25
chr16_75628443_75628594 0.57 ADAT1
adenosine deaminase, tRNA-specific 1
8514
0.13
chr5_161696334_161696596 0.57 GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
174925
0.03
chr12_132345039_132345375 0.57 MMP17
matrix metallopeptidase 17 (membrane-inserted)
15367
0.16
chr14_71165073_71165224 0.57 TTC9
tetratricopeptide repeat domain 9
56644
0.12
chr3_149166374_149166525 0.56 TM4SF4
transmembrane 4 L six family member 4
25312
0.18
chr10_94581825_94581976 0.56 EXOC6
exocyst complex component 6
9035
0.27
chr19_52089706_52089857 0.56 AC018755.1
HCG2008157; Uncharacterized protein; cDNA FLJ30403 fis, clone BRACE2008480
7849
0.12
chr9_21677527_21678485 0.55 ENSG00000244230
.
21307
0.21
chr7_36789268_36789419 0.55 AOAH
acyloxyacyl hydrolase (neutrophil)
25189
0.22
chr1_44693004_44693155 0.54 DMAP1
DNA methyltransferase 1 associated protein 1
13566
0.17
chr4_83933011_83933976 0.54 LIN54
lin-54 homolog (C. elegans)
547
0.73
chr6_7697968_7698508 0.54 BMP6
bone morphogenetic protein 6
28792
0.23
chr10_94520371_94520715 0.54 ENSG00000201412
.
50178
0.13
chr3_4793867_4794159 0.54 ENSG00000239126
.
126373
0.05
chr22_32033546_32033968 0.53 PISD
phosphatidylserine decarboxylase
634
0.74
chr1_159061998_159062403 0.53 AIM2
absent in melanoma 2
15509
0.17
chr17_41081070_41081349 0.53 ENSG00000200510
.
3750
0.1
chr5_173959609_173959903 0.53 MSX2
msh homeobox 2
191780
0.03
chr2_39054904_39055055 0.53 DHX57
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
8729
0.15
chr6_140893365_140893516 0.53 ENSG00000221336
.
88410
0.1
chr16_11734508_11734659 0.53 LITAF
lipopolysaccharide-induced TNF factor
4346
0.22
chr22_24906725_24906876 0.53 AP000355.2

5676
0.15
chr16_48570933_48571121 0.53 RP11-44I10.3

22545
0.17
chr2_161208306_161208457 0.52 ENSG00000252465
.
45098
0.15
chr5_94416178_94416653 0.52 MCTP1
multiple C2 domains, transmembrane 1
771
0.78
chr1_33474618_33474769 0.52 RP1-117O3.2

22017
0.13
chr16_84766426_84766761 0.52 USP10
ubiquitin specific peptidase 10
32947
0.16
chr20_352637_353070 0.52 TRIB3
tribbles pseudokinase 3
8408
0.13
chr9_123446778_123446929 0.51 MEGF9
multiple EGF-like-domains 9
29759
0.21
chr4_139162325_139164249 0.51 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
216
0.97
chr19_42306064_42306215 0.51 CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
5054
0.13
chr8_101804090_101804262 0.51 ENSG00000202001
.
36753
0.12
chr17_25608843_25608994 0.51 ENSG00000263583
.
12104
0.22
chr20_52523665_52523816 0.50 AC005220.3

32959
0.21
chr14_73934175_73934326 0.50 ENSG00000251393
.
5121
0.16
chr20_3993319_3993621 0.50 RNF24
ring finger protein 24
2566
0.31
chr2_97283065_97283216 0.49 KANSL3
KAT8 regulatory NSL complex subunit 3
20906
0.19
chr12_11898918_11899069 0.49 ETV6
ets variant 6
6442
0.31
chr7_130527306_130527457 0.49 ENSG00000226380
.
34199
0.2
chr7_77355828_77355979 0.49 RSBN1L
round spermatid basic protein 1-like
29435
0.2
chr7_65746937_65747265 0.49 TPST1
tyrosylprotein sulfotransferase 1
60510
0.11
chr3_172035613_172035916 0.48 AC092964.1
Uncharacterized protein
1546
0.44
chr8_53372834_53372985 0.48 ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
50544
0.17
chr2_87868562_87868713 0.48 ENSG00000265507
.
60637
0.14
chr11_72451789_72452038 0.48 ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
11535
0.12
chr3_183025030_183025275 0.48 B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
42020
0.14
chr6_36001781_36002122 0.48 MAPK14
mitogen-activated protein kinase 14
5085
0.21
chr3_171678813_171679061 0.47 TMEM212-IT1
TMEM212 intronic transcript 1 (non-protein coding)
66711
0.11
chr22_43288275_43288426 0.47 ARFGAP3
ADP-ribosylation factor GTPase activating protein 3
34238
0.17
chrX_107683395_107684019 0.47 COL4A5
collagen, type IV, alpha 5
595
0.63
chr15_64985334_64985485 0.47 AC100830.4

1831
0.21
chr17_79702501_79703028 0.47 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
22292
0.07
chrX_53292770_53292921 0.47 IQSEC2
IQ motif and Sec7 domain 2
17951
0.16
chr15_94749688_94749858 0.47 MCTP2
multiple C2 domains, transmembrane 2
24994
0.27
chr7_139365740_139366077 0.47 HIPK2
homeodomain interacting protein kinase 2
55933
0.14
chr2_25979688_25979839 0.46 ASXL2
additional sex combs like 2 (Drosophila)
23415
0.18
chr12_120669177_120669328 0.46 PXN
paxillin
4605
0.14
chr1_235010269_235010484 0.46 ENSG00000239690
.
29557
0.2
chr3_10334877_10335066 0.46 GHRL
ghrelin/obestatin prepropeptide
340
0.8
chr5_130976356_130976507 0.46 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
5502
0.32
chr14_33883349_33883500 0.46 NPAS3
neuronal PAS domain protein 3
198906
0.03
chr2_46689171_46689322 0.46 ENSG00000241791
.
13596
0.16
chr13_50783171_50783406 0.46 DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
126981
0.05
chr1_40530106_40530257 0.46 PPT1
palmitoyl-protein thioesterase 1
17812
0.17
chr17_57807955_57808106 0.46 VMP1
vacuole membrane protein 1
954
0.54
chr14_75165335_75165486 0.45 ENSG00000222604
.
13244
0.13
chr1_56968313_56968464 0.45 PPAP2B
phosphatidic acid phosphatase type 2B
76853
0.11
chr10_5723979_5724130 0.45 FAM208B
family with sequence similarity 208, member B
2747
0.23
chr1_8682186_8682337 0.45 RERE
arginine-glutamic acid dipeptide (RE) repeats
2178
0.41
chr7_149318979_149319130 0.45 ZNF767
zinc finger family member 767
2602
0.35
chr19_2169086_2169237 0.45 DOT1L
DOT1-like histone H3K79 methyltransferase
4977
0.13
chr17_76871972_76872123 0.45 TIMP2
TIMP metallopeptidase inhibitor 2
1815
0.27
chr2_219020724_219020875 0.45 CXCR1
chemokine (C-X-C motif) receptor 1
10919
0.14
chr7_23312825_23312976 0.44 MALSU1
mitochondrial assembly of ribosomal large subunit 1
25919
0.17
chr5_39266648_39266799 0.44 FYB
FYN binding protein
4023
0.33
chr18_9869922_9870073 0.44 TXNDC2
thioredoxin domain containing 2 (spermatozoa)
15766
0.16
chr19_18626356_18626507 0.44 ELL
elongation factor RNA polymerase II
6506
0.1
chr4_185331100_185331251 0.44 IRF2
interferon regulatory factor 2
8569
0.21
chr4_13959692_13959843 0.44 ENSG00000252092
.
299516
0.01
chr17_26220981_26221377 0.44 LYRM9
LYR motif containing 9
770
0.4
chr10_125979038_125979189 0.44 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
125907
0.05
chr2_71680397_71681534 0.44 DYSF
dysferlin
113
0.98
chr11_78139082_78139233 0.44 GAB2
GRB2-associated binding protein 2
9763
0.18
chr12_13145535_13145776 0.44 HEBP1
heme binding protein 1
3441
0.17
chr17_5365675_5365826 0.43 DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
6318
0.12
chr5_176935395_176936034 0.43 DOK3
docking protein 3
1113
0.32
chr2_106414710_106414861 0.43 NCK2
NCK adaptor protein 2
18230
0.25
chr3_188301983_188302303 0.43 LPP-AS1
LPP antisense RNA 1
15689
0.2
chr7_5481756_5481907 0.43 TNRC18
trinucleotide repeat containing 18
16786
0.12
chr17_2060784_2060943 0.43 SMG6
SMG6 nonsense mediated mRNA decay factor
15609
0.12
chr2_69809391_69809743 0.42 AAK1
AP2 associated kinase 1
61219
0.1
chr8_48266549_48266761 0.42 SPIDR
scaffolding protein involved in DNA repair
86308
0.1
chr4_40564844_40564995 0.42 RBM47
RNA binding motif protein 47
46929
0.14
chr7_30265425_30265712 0.42 ZNRF2
zinc and ring finger 2
58355
0.1
chr8_142274723_142274874 0.42 RP11-10J21.3
Uncharacterized protein
10134
0.14
chr2_43439997_43440275 0.42 ZFP36L2
ZFP36 ring finger protein-like 2
13612
0.23
chr20_50267277_50267428 0.42 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
87982
0.09
chr15_89710840_89711060 0.42 RLBP1
retinaldehyde binding protein 1
44124
0.12
chr6_11354405_11354556 0.42 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
28052
0.23
chr8_103807477_103808006 0.41 ENSG00000266799
.
61794
0.1
chr21_30672594_30672989 0.41 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
332
0.89
chr7_105316780_105317038 0.41 ATXN7L1
ataxin 7-like 1
2700
0.37
chr2_85937073_85937224 0.41 GNLY
granulysin
14657
0.13
chr1_33812781_33812932 0.41 PHC2
polyhomeotic homolog 2 (Drosophila)
2630
0.17
chr2_197078455_197078606 0.41 ENSG00000239161
.
1516
0.41
chr16_87028312_87028580 0.41 RP11-899L11.3

221075
0.02
chr11_65313728_65314148 0.41 LTBP3
latent transforming growth factor beta binding protein 3
292
0.8
chr6_160411027_160411270 0.41 AIRN
antisense of IGF2R non-protein coding RNA
17548
0.19
chrX_9320798_9321168 0.41 TBL1X
transducin (beta)-like 1X-linked
110352
0.07
chr16_72085557_72085708 0.41 HP
haptoglobin
2859
0.17
chr10_45870253_45870404 0.40 ALOX5
arachidonate 5-lipoxygenase
653
0.77
chr5_150863261_150863412 0.40 ENSG00000200227
.
6198
0.17
chr7_115872079_115872230 0.40 AC073130.3

7151
0.22
chr4_99273774_99274037 0.40 RAP1GDS1
RAP1, GTP-GDP dissociation stimulator 1
26348
0.23
chrX_13093156_13093307 0.40 FAM9C
family with sequence similarity 9, member C
30430
0.22
chr10_26770074_26770395 0.40 ENSG00000199733
.
28284
0.21
chr10_89868275_89868426 0.40 ENSG00000200891
.
113898
0.06
chr2_175495703_175495854 0.40 WIPF1
WAS/WASL interacting protein family, member 1
3529
0.27
chr10_126222901_126223052 0.40 LHPP
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
72564
0.1
chr7_127667480_127667631 0.40 LRRC4
leucine rich repeat containing 4
3503
0.31
chr19_15755544_15755695 0.40 CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
3500
0.23

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of BACH1_NFE2_NFE2L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.2 0.9 GO:0018101 protein citrullination(GO:0018101)
0.2 0.5 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 0.5 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 0.2 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.1 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.1 0.2 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1 0.1 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.1 0.2 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.1 0.2 GO:0019322 pentose biosynthetic process(GO:0019322)
0.1 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 0.2 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.2 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:0009309 amine biosynthetic process(GO:0009309)
0.1 0.2 GO:0090594 wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1 0.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.1 0.2 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.2 GO:0001820 serotonin secretion(GO:0001820)
0.1 0.4 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.4 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0045117 azole transport(GO:0045117)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.3 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.4 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.1 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0002902 regulation of B cell apoptotic process(GO:0002902)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0052553 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.0 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.0 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0002830 positive regulation of type 2 immune response(GO:0002830)
0.0 0.2 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0032661 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.2 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.3 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0071800 podosome assembly(GO:0071800) regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.0 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.1 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 1.0 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0047496 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.0 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.2 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.0 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.2 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.3 GO:0043297 apical junction assembly(GO:0043297)
0.0 0.0 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.2 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.0 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.1 0.2 GO:0042629 mast cell granule(GO:0042629)
0.1 0.2 GO:0044462 external encapsulating structure part(GO:0044462)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.3 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 0.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 0.5 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.2 0.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 0.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.4 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.3 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.0 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0043176 amine binding(GO:0043176)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.0 0.0 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 PID MYC PATHWAY C-MYC pathway
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.0 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex