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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for BACH1_NFE2_NFE2L2

Z-value: 2.46

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol	Gene ID	Gene Info
BACH1 Ensembl NCBI GeneCards UniProt	ENSG00000156273.11	BTB domain and CNC homolog 1
NFE2 Ensembl NCBI GeneCards UniProt	ENSG00000123405.9	nuclear factor, erythroid 2
NFE2L2 Ensembl NCBI GeneCards UniProt	ENSG00000116044.11	nuclear factor, erythroid 2 like 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr21_30689027_30689178	BACH1	10348	0.182548	0.77	1.5e-02	Click!
chr21_30688725_30688876	BACH1	10650	0.182087	0.73	2.4e-02	Click!
chr21_30687972_30688123	BACH1	10523	0.182960	0.70	3.7e-02	Click!
chr21_30620619_30620770	BACH1	50498	0.100138	0.64	6.1e-02	Click!
chr21_30677925_30678103	BACH1	490	0.809035	0.61	8.1e-02	Click!
chr12_54690613_54690897	NFE2	913	0.331553	0.93	3.2e-04	Click!
chr12_54688592_54688942	NFE2	775	0.396851	0.92	4.3e-04	Click!
chr12_54689177_54689328	NFE2	290	0.775354	0.92	4.5e-04	Click!
chr12_54689023_54689174	NFE2	444	0.631982	0.90	9.1e-04	Click!
chr12_54693479_54693635	NFE2	1242	0.210655	0.81	8.6e-03	Click!
chr2_178127025_178127819	NFE2L2	760	0.459348	-0.65	5.8e-02	Click!
chr2_178125992_178126256	NFE2L2	2058	0.186804	-0.48	1.9e-01	Click!
chr2_178104885_178105235	NFE2L2	7845	0.111307	0.46	2.2e-01	Click!
chr2_178125001_178125671	NFE2L2	2846	0.149705	-0.36	3.5e-01	Click!
chr2_178140372_178140777	NFE2L2	10715	0.107506	0.35	3.5e-01	Click!

Activity of the BACH1_NFE2_NFE2L2 motif across conditions

Conditions sorted by the z-value of the BACH1_NFE2_NFE2L2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_233249017_233249707	1.56	PCNXL2	pecanex-like 2 (Drosophila)	46691	0.19
chr10_6443642_6443853	1.24	DKFZP667F0711		51469	0.16
chr19_33784339_33784950	1.16	CTD-2540B15.11		6196	0.14
chr18_47003399_47003645	1.15	RP11-110H1.4		8997	0.09
chr22_47149775_47150260	1.06	CTA-29F11.1		8443	0.18
chr6_147197427_147197865	1.06	STXBP5-AS1	STXBP5 antisense RNA 1	25505	0.25
chr2_111751565_111751824	1.05	ACOXL	acyl-CoA oxidase-like	6919	0.31
chr19_10923780_10924057	1.03	ENSG00000207752	.	4254	0.14
chr1_10475436_10475736	1.03	APITD1	apoptosis-inducing, TAF9-like domain 1	14573	0.1
chr7_115670709_115671033	1.03	TFEC	transcription factor EC	4	0.99
chr17_74442541_74443075	1.02	UBE2O	ubiquitin-conjugating enzyme E2O	6480	0.12
chr9_127520724_127520937	0.98	RP11-175D17.3		11572	0.14
chr11_72446771_72446922	0.97	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	8673	0.12
chr15_59836085_59836236	0.91	ENSG00000201704	.	30261	0.14
chr18_74189003_74189166	0.89	ZNF516	zinc finger protein 516	13651	0.17
chr8_101231400_101231551	0.89	ENSG00000199667	.	34109	0.13
chr1_42175219_42175489	0.86	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	8682	0.27
chr8_52782524_52782885	0.86	PCMTD1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	24399	0.15
chr3_152094299_152094568	0.85	TMEM14E	transmembrane protein 14E	35654	0.17
chr14_35843711_35843965	0.85	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	29508	0.2
chr17_79133489_79133672	0.85	AATK-AS1	AATK antisense RNA 1	5727	0.1
chr4_15659797_15659948	0.84	FBXL5	F-box and leucine-rich repeat protein 5	1615	0.4
chr6_14734934_14735085	0.83	ENSG00000206960	.	88243	0.1
chr17_65427494_65427948	0.83	ENSG00000201547	.	22724	0.12
chr1_17634731_17635053	0.80	PADI4	peptidyl arginine deiminase, type IV	200	0.93
chr12_48170565_48170736	0.79	SLC48A1	solute carrier family 48 (heme transporter), member 1	3659	0.16
chr2_10425679_10425865	0.78	ENSG00000264030	.	5015	0.19
chr15_80452796_80453143	0.77	FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)	4676	0.25
chr4_105982370_105982725	0.76	ENSG00000252136	.	44597	0.16
chr8_132828485_132828822	0.75	EFR3A	EFR3 homolog A (S. cerevisiae)	87682	0.1
chr19_49467193_49467878	0.75	FTL	ferritin, light polypeptide	1023	0.28
chr16_12910185_12910336	0.75	CPPED1	calcineurin-like phosphoesterase domain containing 1	12386	0.18
chr19_16567801_16568854	0.74	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	14427	0.12
chr5_57555667_57556212	0.74	ENSG00000238899	.	189924	0.03
chr11_5618695_5618968	0.73	TRIM6	tripartite motif containing 6	795	0.34
chr15_91459213_91459364	0.73	MAN2A2	mannosidase, alpha, class 2A, member 2	3170	0.11
chr15_58624481_58624632	0.72	ALDH1A2	aldehyde dehydrogenase 1 family, member A2	53094	0.15
chr16_1992022_1992173	0.71	MSRB1	methionine sulfoxide reductase B1	1027	0.22
chr16_21623104_21623255	0.71	METTL9	methyltransferase like 9	242	0.89
chr1_43407500_43407651	0.71	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	10779	0.18
chr17_441417_441568	0.71	RP5-1029F21.2		14314	0.17
chr17_6757690_6757943	0.69	TEKT1	tektin 1	22736	0.14
chr16_31881606_31881883	0.69	ZNF267	zinc finger protein 267	3335	0.29
chr5_171279662_171279813	0.68	SMIM23	small integral membrane protein 23	66847	0.11
chr2_208104248_208104487	0.68	AC007879.5		14609	0.21
chr8_26123485_26124097	0.67	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	25216	0.23
chr6_34253179_34253351	0.67	C6orf1	chromosome 6 open reading frame 1	36018	0.16
chr17_80175660_80175811	0.66	RP13-516M14.2		3632	0.13
chr16_18815542_18815693	0.65	RP11-1035H13.2		1212	0.34
chr8_56814335_56814486	0.65	ENSG00000199405	.	1004	0.46
chr7_1570565_1570716	0.64	MAFK	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	290	0.87
chr12_56075239_56075869	0.64	METTL7B	methyltransferase like 7B	224	0.86
chr21_19157038_19157189	0.64	AL109761.5		8692	0.24
chr3_187491731_187491915	0.64	BCL6	B-cell CLL/lymphoma 6	28308	0.2
chr1_56982304_56982688	0.63	PPAP2B	phosphatidic acid phosphatase type 2B	62745	0.14
chr20_1550154_1550305	0.63	SIRPB1	signal-regulatory protein beta 1	2329	0.22
chr16_28607764_28607915	0.63	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	38	0.96
chrX_109330942_109331348	0.62	ENSG00000265584	.	5799	0.25
chr6_13273500_13273733	0.62	PHACTR1	phosphatase and actin regulator 1	627	0.46
chr15_94779920_94780071	0.62	MCTP2	multiple C2 domains, transmembrane 2	5228	0.35
chr7_44678436_44678587	0.62	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	14450	0.18
chr10_115604050_115604207	0.62	DCLRE1A	DNA cross-link repair 1A	9731	0.17
chr9_136710503_136710686	0.62	SARDH	sarcosine dehydrogenase	105517	0.06
chr6_34632212_34632529	0.62	C6orf106	chromosome 6 open reading frame 106	7363	0.14
chr12_124252082_124252425	0.61	DNAH10	dynein, axonemal, heavy chain 10	5211	0.19
chr7_36636829_36636980	0.61	AOAH	acyloxyacyl hydrolase (neutrophil)	2642	0.26
chr15_90420057_90420208	0.61	ENSG00000264796	.	7130	0.11
chr19_8307301_8307493	0.60	CTD-3020H12.4		2865	0.2
chr7_1553073_1553492	0.59	AC102953.6		4219	0.16
chr8_131012205_131012356	0.59	ENSG00000253043	.	4567	0.2
chr5_177904286_177904437	0.59	CTB-26E19.1		34266	0.18
chr5_150439543_150439694	0.59	TNIP1	TNFAIP3 interacting protein 1	5038	0.22
chr1_221219794_221220024	0.59	HLX	H2.0-like homeobox	165325	0.04
chr2_160711950_160712101	0.58	LY75	lymphocyte antigen 75	49168	0.13
chr16_88367140_88367361	0.58	ZNF469	zinc finger protein 469	126629	0.05
chr6_133069776_133069927	0.58	RP1-55C23.7		3963	0.15
chr5_39270484_39270720	0.58	FYB	FYN binding protein	144	0.98
chr13_78659821_78660303	0.57	RNF219-AS1	RNF219 antisense RNA 1	30772	0.24
chr12_51720692_51720843	0.57	BIN2	bridging integrator 2	2315	0.25
chr16_75628443_75628594	0.57	ADAT1	adenosine deaminase, tRNA-specific 1	8514	0.13
chr5_161696334_161696596	0.57	GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	174925	0.03
chr12_132345039_132345375	0.57	MMP17	matrix metallopeptidase 17 (membrane-inserted)	15367	0.16
chr14_71165073_71165224	0.57	TTC9	tetratricopeptide repeat domain 9	56644	0.12
chr3_149166374_149166525	0.56	TM4SF4	transmembrane 4 L six family member 4	25312	0.18
chr10_94581825_94581976	0.56	EXOC6	exocyst complex component 6	9035	0.27
chr19_52089706_52089857	0.56	AC018755.1	HCG2008157; Uncharacterized protein; cDNA FLJ30403 fis, clone BRACE2008480	7849	0.12
chr9_21677527_21678485	0.55	ENSG00000244230	.	21307	0.21
chr7_36789268_36789419	0.55	AOAH	acyloxyacyl hydrolase (neutrophil)	25189	0.22
chr1_44693004_44693155	0.54	DMAP1	DNA methyltransferase 1 associated protein 1	13566	0.17
chr4_83933011_83933976	0.54	LIN54	lin-54 homolog (C. elegans)	547	0.73
chr6_7697968_7698508	0.54	BMP6	bone morphogenetic protein 6	28792	0.23
chr10_94520371_94520715	0.54	ENSG00000201412	.	50178	0.13
chr3_4793867_4794159	0.54	ENSG00000239126	.	126373	0.05
chr22_32033546_32033968	0.53	PISD	phosphatidylserine decarboxylase	634	0.74
chr1_159061998_159062403	0.53	AIM2	absent in melanoma 2	15509	0.17
chr17_41081070_41081349	0.53	ENSG00000200510	.	3750	0.1
chr5_173959609_173959903	0.53	MSX2	msh homeobox 2	191780	0.03
chr2_39054904_39055055	0.53	DHX57	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57	8729	0.15
chr6_140893365_140893516	0.53	ENSG00000221336	.	88410	0.1
chr16_11734508_11734659	0.53	LITAF	lipopolysaccharide-induced TNF factor	4346	0.22
chr22_24906725_24906876	0.53	AP000355.2		5676	0.15
chr16_48570933_48571121	0.53	RP11-44I10.3		22545	0.17
chr2_161208306_161208457	0.52	ENSG00000252465	.	45098	0.15
chr5_94416178_94416653	0.52	MCTP1	multiple C2 domains, transmembrane 1	771	0.78
chr1_33474618_33474769	0.52	RP1-117O3.2		22017	0.13
chr16_84766426_84766761	0.52	USP10	ubiquitin specific peptidase 10	32947	0.16
chr20_352637_353070	0.52	TRIB3	tribbles pseudokinase 3	8408	0.13
chr9_123446778_123446929	0.51	MEGF9	multiple EGF-like-domains 9	29759	0.21
chr4_139162325_139164249	0.51	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	216	0.97
chr19_42306064_42306215	0.51	CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	5054	0.13
chr8_101804090_101804262	0.51	ENSG00000202001	.	36753	0.12
chr17_25608843_25608994	0.51	ENSG00000263583	.	12104	0.22
chr20_52523665_52523816	0.50	AC005220.3		32959	0.21
chr14_73934175_73934326	0.50	ENSG00000251393	.	5121	0.16
chr20_3993319_3993621	0.50	RNF24	ring finger protein 24	2566	0.31
chr2_97283065_97283216	0.49	KANSL3	KAT8 regulatory NSL complex subunit 3	20906	0.19
chr12_11898918_11899069	0.49	ETV6	ets variant 6	6442	0.31
chr7_130527306_130527457	0.49	ENSG00000226380	.	34199	0.2
chr7_77355828_77355979	0.49	RSBN1L	round spermatid basic protein 1-like	29435	0.2
chr7_65746937_65747265	0.49	TPST1	tyrosylprotein sulfotransferase 1	60510	0.11
chr3_172035613_172035916	0.48	AC092964.1	Uncharacterized protein	1546	0.44
chr8_53372834_53372985	0.48	ST18	suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)	50544	0.17
chr2_87868562_87868713	0.48	ENSG00000265507	.	60637	0.14
chr11_72451789_72452038	0.48	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	11535	0.12
chr3_183025030_183025275	0.48	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	42020	0.14
chr6_36001781_36002122	0.48	MAPK14	mitogen-activated protein kinase 14	5085	0.21
chr3_171678813_171679061	0.47	TMEM212-IT1	TMEM212 intronic transcript 1 (non-protein coding)	66711	0.11
chr22_43288275_43288426	0.47	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	34238	0.17
chrX_107683395_107684019	0.47	COL4A5	collagen, type IV, alpha 5	595	0.63
chr15_64985334_64985485	0.47	AC100830.4		1831	0.21
chr17_79702501_79703028	0.47	SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	22292	0.07
chrX_53292770_53292921	0.47	IQSEC2	IQ motif and Sec7 domain 2	17951	0.16
chr15_94749688_94749858	0.47	MCTP2	multiple C2 domains, transmembrane 2	24994	0.27
chr7_139365740_139366077	0.47	HIPK2	homeodomain interacting protein kinase 2	55933	0.14
chr2_25979688_25979839	0.46	ASXL2	additional sex combs like 2 (Drosophila)	23415	0.18
chr12_120669177_120669328	0.46	PXN	paxillin	4605	0.14
chr1_235010269_235010484	0.46	ENSG00000239690	.	29557	0.2
chr3_10334877_10335066	0.46	GHRL	ghrelin/obestatin prepropeptide	340	0.8
chr5_130976356_130976507	0.46	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	5502	0.32
chr14_33883349_33883500	0.46	NPAS3	neuronal PAS domain protein 3	198906	0.03
chr2_46689171_46689322	0.46	ENSG00000241791	.	13596	0.16
chr13_50783171_50783406	0.46	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	126981	0.05
chr1_40530106_40530257	0.46	PPT1	palmitoyl-protein thioesterase 1	17812	0.17
chr17_57807955_57808106	0.46	VMP1	vacuole membrane protein 1	954	0.54
chr14_75165335_75165486	0.45	ENSG00000222604	.	13244	0.13
chr1_56968313_56968464	0.45	PPAP2B	phosphatidic acid phosphatase type 2B	76853	0.11
chr10_5723979_5724130	0.45	FAM208B	family with sequence similarity 208, member B	2747	0.23
chr1_8682186_8682337	0.45	RERE	arginine-glutamic acid dipeptide (RE) repeats	2178	0.41
chr7_149318979_149319130	0.45	ZNF767	zinc finger family member 767	2602	0.35
chr19_2169086_2169237	0.45	DOT1L	DOT1-like histone H3K79 methyltransferase	4977	0.13
chr17_76871972_76872123	0.45	TIMP2	TIMP metallopeptidase inhibitor 2	1815	0.27
chr2_219020724_219020875	0.45	CXCR1	chemokine (C-X-C motif) receptor 1	10919	0.14
chr7_23312825_23312976	0.44	MALSU1	mitochondrial assembly of ribosomal large subunit 1	25919	0.17
chr5_39266648_39266799	0.44	FYB	FYN binding protein	4023	0.33
chr18_9869922_9870073	0.44	TXNDC2	thioredoxin domain containing 2 (spermatozoa)	15766	0.16
chr19_18626356_18626507	0.44	ELL	elongation factor RNA polymerase II	6506	0.1
chr4_185331100_185331251	0.44	IRF2	interferon regulatory factor 2	8569	0.21
chr4_13959692_13959843	0.44	ENSG00000252092	.	299516	0.01
chr17_26220981_26221377	0.44	LYRM9	LYR motif containing 9	770	0.4
chr10_125979038_125979189	0.44	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	125907	0.05
chr2_71680397_71681534	0.44	DYSF	dysferlin	113	0.98
chr11_78139082_78139233	0.44	GAB2	GRB2-associated binding protein 2	9763	0.18
chr12_13145535_13145776	0.44	HEBP1	heme binding protein 1	3441	0.17
chr17_5365675_5365826	0.43	DHX33	DEAH (Asp-Glu-Ala-His) box polypeptide 33	6318	0.12
chr5_176935395_176936034	0.43	DOK3	docking protein 3	1113	0.32
chr2_106414710_106414861	0.43	NCK2	NCK adaptor protein 2	18230	0.25
chr3_188301983_188302303	0.43	LPP-AS1	LPP antisense RNA 1	15689	0.2
chr7_5481756_5481907	0.43	TNRC18	trinucleotide repeat containing 18	16786	0.12
chr17_2060784_2060943	0.43	SMG6	SMG6 nonsense mediated mRNA decay factor	15609	0.12
chr2_69809391_69809743	0.42	AAK1	AP2 associated kinase 1	61219	0.1
chr8_48266549_48266761	0.42	SPIDR	scaffolding protein involved in DNA repair	86308	0.1
chr4_40564844_40564995	0.42	RBM47	RNA binding motif protein 47	46929	0.14
chr7_30265425_30265712	0.42	ZNRF2	zinc and ring finger 2	58355	0.1
chr8_142274723_142274874	0.42	RP11-10J21.3	Uncharacterized protein	10134	0.14
chr2_43439997_43440275	0.42	ZFP36L2	ZFP36 ring finger protein-like 2	13612	0.23
chr20_50267277_50267428	0.42	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	87982	0.09
chr15_89710840_89711060	0.42	RLBP1	retinaldehyde binding protein 1	44124	0.12
chr6_11354405_11354556	0.42	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	28052	0.23
chr8_103807477_103808006	0.41	ENSG00000266799	.	61794	0.1
chr21_30672594_30672989	0.41	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	332	0.89
chr7_105316780_105317038	0.41	ATXN7L1	ataxin 7-like 1	2700	0.37
chr2_85937073_85937224	0.41	GNLY	granulysin	14657	0.13
chr1_33812781_33812932	0.41	PHC2	polyhomeotic homolog 2 (Drosophila)	2630	0.17
chr2_197078455_197078606	0.41	ENSG00000239161	.	1516	0.41
chr16_87028312_87028580	0.41	RP11-899L11.3		221075	0.02
chr11_65313728_65314148	0.41	LTBP3	latent transforming growth factor beta binding protein 3	292	0.8
chr6_160411027_160411270	0.41	AIRN	antisense of IGF2R non-protein coding RNA	17548	0.19
chrX_9320798_9321168	0.41	TBL1X	transducin (beta)-like 1X-linked	110352	0.07
chr16_72085557_72085708	0.41	HP	haptoglobin	2859	0.17
chr10_45870253_45870404	0.40	ALOX5	arachidonate 5-lipoxygenase	653	0.77
chr5_150863261_150863412	0.40	ENSG00000200227	.	6198	0.17
chr7_115872079_115872230	0.40	AC073130.3		7151	0.22
chr4_99273774_99274037	0.40	RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1	26348	0.23
chrX_13093156_13093307	0.40	FAM9C	family with sequence similarity 9, member C	30430	0.22
chr10_26770074_26770395	0.40	ENSG00000199733	.	28284	0.21
chr10_89868275_89868426	0.40	ENSG00000200891	.	113898	0.06
chr2_175495703_175495854	0.40	WIPF1	WAS/WASL interacting protein family, member 1	3529	0.27
chr10_126222901_126223052	0.40	LHPP	phospholysine phosphohistidine inorganic pyrophosphate phosphatase	72564	0.1
chr7_127667480_127667631	0.40	LRRC4	leucine rich repeat containing 4	3503	0.31
chr19_15755544_15755695	0.40	CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	3500	0.23

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.2	0.9	GO:0018101	protein citrullination(GO:0018101)
0.2	0.5	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.4	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.4	GO:0030091	protein repair(GO:0030091)
0.1	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.1	0.2	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.4	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.2	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.5	GO:0043302	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1	0.2	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.2	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.2	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.1	0.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.1	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.1	0.2	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1	0.1	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.1	0.2	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.1	0.2	GO:0019322	pentose biosynthetic process(GO:0019322)
0.1	0.3	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.1	0.2	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.2	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.2	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.1	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.7	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.7	GO:0009309	amine biosynthetic process(GO:0009309)
0.1	0.2	GO:0090594	wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.1	0.2	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.2	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1	0.2	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.1	0.2	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.2	GO:0001820	serotonin secretion(GO:0001820)
0.1	0.4	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.3	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.4	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0045117	azole transport(GO:0045117)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.3	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.2	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.3	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.2	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.4	GO:0090398	cellular senescence(GO:0090398)
0.0	0.1	GO:0015682	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.3	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.2	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.2	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.1	GO:2001279	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0002902	regulation of B cell apoptotic process(GO:0002902)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.0	GO:0052553	modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.2	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.2	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.2	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.4	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.0	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.0	0.2	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:0006595	polyamine metabolic process(GO:0006595)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.2	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.0	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0061526	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.3	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800) regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.4	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.1	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.0	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0051043	regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	1.0	GO:0055072	iron ion homeostasis(GO:0055072)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.0	0.1	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.2	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.4	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.0	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.2	GO:0006826	iron ion transport(GO:0006826)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.2	GO:0070206	protein trimerization(GO:0070206)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0002279	mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0	0.0	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0051818	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.1	GO:0042554	superoxide anion generation(GO:0042554)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.2	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.3	GO:0043297	apical junction assembly(GO:0043297)
0.0	0.0	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.2	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.0	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.0	0.1	GO:0046697	decidualization(GO:0046697)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.2	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.0	GO:0072179	nephric duct formation(GO:0072179)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.0	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.0	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.0	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.4	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.1	0.2	GO:0044462	external encapsulating structure part(GO:0044462)
0.1	0.3	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.3	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.2	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.5	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.3	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.2	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.6	GO:0016605	PML body(GO:0016605)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.2	0.6	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.2	0.5	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2	0.5	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.2	0.5	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	0.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.4	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.9	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.4	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.1	0.3	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.3	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0004370	glycerol kinase activity(GO:0004370)
0.1	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.5	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.3	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.1	0.3	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	0.2	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.3	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.3	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.6	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.3	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.9	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.3	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.3	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.2	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.6	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.2	GO:0043176	amine binding(GO:0043176)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.3	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.4	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.2	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0042171	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.2	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0032135	DNA insertion or deletion binding(GO:0032135)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0051861	glycolipid binding(GO:0051861)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.0	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.9	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.6	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.5	PID ATM PATHWAY	ATM pathway
0.0	0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID MYC PATHWAY	C-MYC pathway
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.8	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.0	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.0	0.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.0	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex

Results for BACH1_NFE2_NFE2L2

Z-value: 2.46

Motif logo

Transcription factors associated with BACH1_NFE2_NFE2L2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the BACH1_NFE2_NFE2L2 motif across conditions

Conditions sorted by the z-value of the BACH1_NFE2_NFE2L2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: