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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for BARHL2

Z-value: 1.50

Motif logo

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Transcription factors associated with BARHL2

Gene Symbol Gene ID Gene Info
ENSG00000143032.7 BARHL2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
BARHL2chr1_91300692_913008431179730.0651640.835.8e-03Click!
BARHL2chr1_91301438_913015891187190.064515-0.674.9e-02Click!
BARHL2chr1_91191755_9119197990730.2966360.571.1e-01Click!
BARHL2chr1_91195192_91195343124730.287589-0.501.7e-01Click!
BARHL2chr1_91190982_9119116182770.2994680.412.7e-01Click!

Activity of the BARHL2 motif across conditions

Conditions sorted by the z-value of the BARHL2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_21677527_21678485 1.09 ENSG00000244230
.
21307
0.21
chr6_19691587_19692480 1.02 ENSG00000200957
.
49273
0.18
chr9_18474095_18474958 0.98 ADAMTSL1
ADAMTS-like 1
295
0.95
chr9_18976648_18977105 0.94 FAM154A
family with sequence similarity 154, member A
56310
0.1
chr15_96881050_96881298 0.84 ENSG00000222651
.
4684
0.17
chr11_123178720_123179203 0.83 ENSG00000200496
.
6863
0.25
chr12_66122461_66123138 0.82 HMGA2
high mobility group AT-hook 2
95112
0.08
chr1_98514169_98514606 0.78 ENSG00000225206
.
2660
0.42
chr16_62068318_62068835 0.77 CDH8
cadherin 8, type 2
462
0.9
chr5_88120627_88121096 0.76 MEF2C
myocyte enhancer factor 2C
704
0.78
chr1_45083000_45083241 0.73 RNF220
ring finger protein 220
8878
0.17
chr6_100729238_100729940 0.73 RP1-121G13.2

145405
0.05
chr9_13278507_13279169 0.72 RP11-272P10.2

348
0.67
chr13_38445031_38445182 0.72 TRPC4
transient receptor potential cation channel, subfamily C, member 4
544
0.83
chr6_28442401_28443147 0.71 ZSCAN23
zinc finger and SCAN domain containing 23
31530
0.13
chr8_37350646_37351319 0.71 RP11-150O12.6

23557
0.24
chr9_22006120_22006693 0.71 CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
2546
0.22
chr13_110957949_110958238 0.70 COL4A2
collagen, type IV, alpha 2
66
0.97
chr7_25901481_25901888 0.70 ENSG00000199085
.
87922
0.1
chr10_114714851_114715858 0.70 RP11-57H14.2

3720
0.26
chr3_157822422_157822707 0.69 SHOX2
short stature homeobox 2
519
0.7
chr14_29859562_29859789 0.69 ENSG00000257522
.
11813
0.29
chr2_158113918_158114875 0.68 GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
286
0.93
chr11_47528811_47529057 0.68 RP11-750H9.7

7507
0.1
chr6_1613704_1614304 0.68 FOXC1
forkhead box C1
3323
0.37
chr1_68697735_68698156 0.68 WLS
wntless Wnt ligand secretion mediator
18
0.98
chr6_2111373_2111600 0.66 GMDS
GDP-mannose 4,6-dehydratase
64739
0.15
chr3_87036535_87037613 0.66 VGLL3
vestigial like 3 (Drosophila)
2778
0.42
chr3_175244326_175245006 0.65 ENSG00000201648
.
82601
0.1
chr4_183371343_183371494 0.64 TENM3
teneurin transmembrane protein 3
1266
0.6
chr6_148829582_148830289 0.63 ENSG00000223322
.
15441
0.29
chr18_53253101_53253291 0.63 TCF4
transcription factor 4
1
0.99
chr8_127837007_127837644 0.63 ENSG00000212451
.
153558
0.04
chr1_163039219_163039545 0.62 RGS4
regulator of G-protein signaling 4
231
0.96
chr12_46949518_46949939 0.62 SLC38A2
solute carrier family 38, member 2
183078
0.03
chr11_122049732_122050124 0.61 ENSG00000207994
.
26912
0.16
chr13_99629621_99629906 0.61 DOCK9
dedicator of cytokinesis 9
481
0.85
chr1_214723042_214723197 0.61 PTPN14
protein tyrosine phosphatase, non-receptor type 14
1447
0.54
chr13_38172411_38172686 0.61 POSTN
periostin, osteoblast specific factor
315
0.95
chr5_10306978_10307734 0.61 CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
782
0.53
chr4_86749229_86749793 0.60 ARHGAP24
Rho GTPase activating protein 24
465
0.88
chr16_54970178_54971110 0.59 IRX5
iroquois homeobox 5
4660
0.36
chr17_1994078_1994475 0.59 RP11-667K14.5

1301
0.3
chr1_159061998_159062403 0.59 AIM2
absent in melanoma 2
15509
0.17
chr9_86875979_86876265 0.59 RP11-380F14.2

17012
0.26
chr22_36318094_36318307 0.59 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
16745
0.27
chr4_126311427_126311944 0.58 FAT4
FAT atypical cadherin 4
3406
0.33
chr9_4137636_4137913 0.58 GLIS3
GLIS family zinc finger 3
7419
0.28
chr22_46471692_46472277 0.58 FLJ27365
hsa-mir-4763
4208
0.11
chr11_46237993_46238166 0.57 CTD-2589M5.4

58019
0.1
chr7_82072002_82072462 0.57 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
799
0.78
chr11_12701583_12701887 0.57 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
4685
0.33
chr5_88080560_88081020 0.56 MEF2C
myocyte enhancer factor 2C
38815
0.18
chr3_134050593_134051228 0.56 AMOTL2
angiomotin like 2
39844
0.16
chr12_72663874_72664300 0.56 ENSG00000236333
.
1684
0.39
chr20_14316163_14316462 0.56 FLRT3
fibronectin leucine rich transmembrane protein 3
1942
0.4
chr5_180523773_180523999 0.55 OR2V1
olfactory receptor, family 2, subfamily V, member 1
28418
0.12
chr6_85823864_85824548 0.55 NT5E
5'-nucleotidase, ecto (CD73)
335603
0.01
chr4_89977525_89978081 0.55 FAM13A
family with sequence similarity 13, member A
508
0.85
chr10_95241473_95241734 0.54 MYOF
myoferlin
348
0.88
chr9_128521797_128522422 0.54 PBX3
pre-B-cell leukemia homeobox 3
11631
0.27
chr6_82476683_82477150 0.54 ENSG00000206886
.
3175
0.27
chr4_175075425_175075781 0.54 FBXO8
F-box protein 8
129211
0.05
chr9_18473246_18473461 0.53 ADAMTSL1
ADAMTS-like 1
539
0.87
chr8_116675050_116675578 0.53 TRPS1
trichorhinophalangeal syndrome I
1409
0.6
chrX_34671991_34672311 0.53 TMEM47
transmembrane protein 47
3254
0.41
chr18_59272997_59273487 0.53 CDH20
cadherin 20, type 2
56143
0.17
chr5_16934329_16934610 0.53 MYO10
myosin X
1578
0.42
chr12_106530238_106530817 0.53 NUAK1
NUAK family, SNF1-like kinase, 1
3284
0.3
chr4_107956832_107957922 0.53 DKK2
dickkopf WNT signaling pathway inhibitor 2
77
0.99
chr6_163840513_163841070 0.53 QKI
QKI, KH domain containing, RNA binding
3375
0.39
chrX_48827968_48828898 0.53 KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
457
0.67
chr12_50596367_50596666 0.52 LIMA1
LIM domain and actin binding 1
621
0.61
chr7_130479581_130479757 0.52 KLF14
Kruppel-like factor 14
60781
0.12
chr19_6274375_6274631 0.52 MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
5456
0.15
chr15_37175433_37176047 0.52 ENSG00000212511
.
30899
0.23
chr5_158465637_158465871 0.52 CTD-2363C16.2

52940
0.13
chr2_159825200_159826543 0.52 TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
688
0.73
chr11_27491201_27491490 0.51 RP11-159H22.2

1931
0.27
chr5_123252700_123253101 0.51 CSNK1G3
casein kinase 1, gamma 3
328781
0.01
chr9_74975903_74976197 0.51 ZFAND5
zinc finger, AN1-type domain 5
3492
0.33
chr4_123704650_123705065 0.51 FGF2
fibroblast growth factor 2 (basic)
43006
0.13
chr2_46547328_46547516 0.51 EPAS1
endothelial PAS domain protein 1
22881
0.23
chr9_113799034_113800104 0.51 LPAR1
lysophosphatidic acid receptor 1
754
0.74
chr11_58730865_58731226 0.51 RP11-142C4.6

15713
0.15
chr4_157891142_157892336 0.51 PDGFC
platelet derived growth factor C
316
0.91
chr5_84589012_84589394 0.51 ENSG00000215953
.
234749
0.02
chr2_207077209_207077426 0.50 GPR1
G protein-coupled receptor 1
778
0.55
chr3_87038506_87038677 0.50 VGLL3
vestigial like 3 (Drosophila)
1261
0.64
chr10_12376015_12376474 0.50 ENSG00000264036
.
5856
0.19
chr4_139812849_139813017 0.50 RP11-371F15.3

46202
0.15
chr14_73929626_73929971 0.50 ENSG00000251393
.
669
0.64
chr9_80437599_80437890 0.50 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
171
0.98
chr10_74854370_74854615 0.50 P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
2116
0.19
chr15_37394480_37395011 0.49 MEIS2
Meis homeobox 2
1241
0.49
chr19_9473504_9474272 0.49 ZNF177
zinc finger protein 177
181
0.93
chr13_73081776_73081993 0.49 ENSG00000251715
.
47145
0.15
chr1_204034501_204034712 0.49 SOX13
SRY (sex determining region Y)-box 13
8126
0.2
chr1_98499845_98500395 0.49 ENSG00000225206
.
10787
0.31
chr15_96878987_96879612 0.49 ENSG00000222651
.
2809
0.21
chr3_181434209_181434555 0.49 SOX2
SRY (sex determining region Y)-box 2
4660
0.26
chr15_47476270_47477144 0.49 SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
409
0.87
chrX_115371447_115371702 0.49 AGTR2
angiotensin II receptor, type 2
69599
0.13
chrX_114796559_114796881 0.48 RP1-93I3.1

314
0.83
chr3_79216626_79216907 0.48 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
148157
0.05
chr2_237087502_237088103 0.48 GBX2
gastrulation brain homeobox 2
10790
0.15
chr8_94507892_94508285 0.48 ENSG00000222416
.
54583
0.14
chr2_188418561_188419245 0.48 AC007319.1

27
0.69
chr6_104566709_104566890 0.48 ENSG00000202283
.
535789
0.0
chr15_32975034_32975352 0.48 RP11-1000B6.2

9927
0.16
chr4_15685369_15685921 0.48 FAM200B
family with sequence similarity 200, member B
2216
0.26
chr8_18870397_18870669 0.47 PSD3
pleckstrin and Sec7 domain containing 3
663
0.74
chr11_131780111_131780399 0.47 NTM
neurotrimin
642
0.77
chr9_110310779_110311295 0.47 KLF4
Kruppel-like factor 4 (gut)
58274
0.13
chr10_76684287_76684702 0.47 KAT6B
K(lysine) acetyltransferase 6B
86036
0.08
chr7_130606573_130606804 0.47 ENSG00000226380
.
44390
0.16
chr3_88191159_88191414 0.47 ZNF654
zinc finger protein 654
3032
0.24
chrX_130036036_130037401 0.47 ENOX2
ecto-NOX disulfide-thiol exchanger 2
460
0.9
chr6_28616143_28617086 0.47 ENSG00000272278
.
572
0.79
chr8_60538222_60538702 0.46 ENSG00000201763
.
170018
0.04
chr8_79468522_79468695 0.46 PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
34858
0.19
chr1_168440138_168440500 0.46 XCL2
chemokine (C motif) ligand 2
72916
0.1
chr2_190042287_190042516 0.46 COL5A2
collagen, type V, alpha 2
2204
0.37
chr6_35286420_35286751 0.46 DEF6
differentially expressed in FDCP 6 homolog (mouse)
9070
0.18
chr13_21654404_21654812 0.46 LATS2
large tumor suppressor kinase 2
18922
0.14
chr9_91607039_91607418 0.46 S1PR3
sphingosine-1-phosphate receptor 3
866
0.53
chr5_61389615_61389794 0.46 ENSG00000251983
.
52788
0.18
chr14_30664453_30664650 0.46 PRKD1
protein kinase D1
3447
0.39
chr2_152214605_152215087 0.45 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
740
0.63
chr5_88178054_88178448 0.45 MEF2C
myocyte enhancer factor 2C
713
0.52
chr9_116639319_116639890 0.45 ZNF618
zinc finger protein 618
974
0.68
chr13_97927308_97927620 0.45 MBNL2
muscleblind-like splicing regulator 2
994
0.69
chr11_63915867_63916232 0.45 MACROD1
MACRO domain containing 1
17484
0.09
chr21_17909068_17909746 0.45 ENSG00000207638
.
2002
0.33
chr3_64670816_64671530 0.45 ADAMTS9-AS2
ADAMTS9 antisense RNA 2
369
0.87
chr13_80912572_80913077 0.45 SPRY2
sprouty homolog 2 (Drosophila)
970
0.67
chr19_10445253_10445455 0.45 ICAM3
intercellular adhesion molecule 3
45
0.92
chr3_172035927_172036370 0.45 AC092964.1
Uncharacterized protein
1930
0.38
chr1_243415347_243415602 0.44 CEP170
centrosomal protein 170kDa
1148
0.47
chr8_62625183_62625719 0.44 ASPH
aspartate beta-hydroxylase
1633
0.37
chr2_74606600_74607395 0.44 DCTN1
dynactin 1
413
0.73
chr6_151088648_151089017 0.44 PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
46608
0.16
chr4_181928306_181928668 0.44 ENSG00000251742
.
827774
0.0
chr3_149297530_149297767 0.44 WWTR1
WW domain containing transcription regulator 1
3609
0.26
chr11_12849556_12849989 0.44 RP11-47J17.3

4558
0.23
chr4_187646262_187646501 0.44 FAT1
FAT atypical cadherin 1
1372
0.58
chr14_78432151_78432727 0.44 ENSG00000199440
.
144954
0.04
chr12_89845524_89845923 0.44 POC1B
POC1 centriolar protein B
45311
0.13
chr12_59312115_59312531 0.44 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
1004
0.56
chr3_64672065_64672629 0.43 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
1008
0.5
chr10_18629419_18629841 0.43 CACNB2
calcium channel, voltage-dependent, beta 2 subunit
36
0.99
chr4_85886471_85886934 0.43 WDFY3
WD repeat and FYVE domain containing 3
801
0.75
chr6_121843994_121844420 0.43 ENSG00000201379
.
19565
0.2
chr3_64251338_64251770 0.43 PRICKLE2
prickle homolog 2 (Drosophila)
2101
0.4
chr2_159824497_159824936 0.43 TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
430
0.86
chr7_87974817_87974968 0.43 STEAP4
STEAP family member 4
38686
0.17
chr13_38172158_38172314 0.43 POSTN
periostin, osteoblast specific factor
627
0.84
chr17_79317268_79317735 0.43 TMEM105
transmembrane protein 105
13027
0.13
chr11_69454777_69455129 0.43 CCND1
cyclin D1
902
0.63
chr8_72273557_72273741 0.43 EYA1
eyes absent homolog 1 (Drosophila)
446
0.9
chr1_114522595_114522893 0.43 OLFML3
olfactomedin-like 3
49
0.97
chr8_23267788_23267947 0.43 LOXL2
lysyl oxidase-like 2
6114
0.2
chr7_107807952_107808196 0.42 NRCAM
neuronal cell adhesion molecule
7728
0.24
chr7_7161828_7161979 0.42 ENSG00000201218
.
19591
0.13
chr1_100112572_100112850 0.42 PALMD
palmdelphin
962
0.68
chr15_38164800_38165190 0.42 TMCO5A
transmembrane and coiled-coil domains 5A
49145
0.2
chr13_67804057_67805835 0.42 PCDH9
protocadherin 9
478
0.9
chr1_224805331_224805508 0.42 CNIH3
cornichon family AMPA receptor auxiliary protein 3
1424
0.35
chr1_41575455_41576018 0.42 SCMH1
sex comb on midleg homolog 1 (Drosophila)
49869
0.15
chr12_116008040_116008436 0.42 ENSG00000240205
.
147292
0.05
chr9_935405_935889 0.42 DMRT3
doublesex and mab-3 related transcription factor 3
41317
0.17
chr10_17256481_17257128 0.42 VIM-AS1
VIM antisense RNA 1
12093
0.15
chr10_729219_729444 0.42 DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
6275
0.18
chr5_40552090_40552408 0.42 ENSG00000199552
.
102816
0.07
chr11_12529707_12530128 0.42 PARVA
parvin, alpha
55635
0.15
chr6_54000748_54000899 0.42 MLIP
muscular LMNA-interacting protein
24515
0.22
chr9_130399731_130400130 0.42 STXBP1
syntaxin binding protein 1
25362
0.12
chr5_107041117_107041487 0.42 ENSG00000239708
.
29465
0.21
chr19_33784339_33784950 0.42 CTD-2540B15.11

6196
0.14
chr9_89952337_89952906 0.42 ENSG00000212421
.
77256
0.11
chr3_166001570_166001765 0.42 ENSG00000251759
.
386243
0.01
chr1_214722890_214723041 0.42 PTPN14
protein tyrosine phosphatase, non-receptor type 14
1601
0.51
chr22_46476561_46476775 0.42 FLJ27365
hsa-mir-4763
476
0.66
chr5_92280974_92281241 0.41 ENSG00000221810
.
227887
0.02
chr3_11681791_11681953 0.41 VGLL4
vestigial like 4 (Drosophila)
3526
0.27
chr1_120191467_120191618 0.41 ZNF697
zinc finger protein 697
1146
0.52
chr4_26461123_26461322 0.41 CCKAR
cholecystokinin A receptor
30862
0.19
chr17_70119242_70119466 0.41 SOX9
SRY (sex determining region Y)-box 9
2193
0.46
chr7_134464463_134465343 0.41 CALD1
caldesmon 1
474
0.89
chrX_3379855_3380017 0.41 ENSG00000212214
.
70356
0.11
chr10_16992831_16993197 0.41 CUBN
cubilin (intrinsic factor-cobalamin receptor)
33180
0.22
chr12_50608031_50608224 0.41 RP3-405J10.4

5260
0.13
chr12_117421145_117421359 0.41 RP11-231I16.1

3890
0.29
chr21_33893367_33893849 0.40 ENSG00000252045
.
17001
0.16
chr7_92327766_92328157 0.40 ENSG00000206763
.
3167
0.33
chr7_14028526_14029745 0.40 ETV1
ets variant 1
156
0.97
chr7_17030060_17030455 0.40 AGR3
anterior gradient 3
108646
0.07
chr1_92317111_92317363 0.40 TGFBR3
transforming growth factor, beta receptor III
9913
0.22
chr8_48392698_48393140 0.40 SPIDR
scaffolding protein involved in DNA repair
39956
0.18
chr5_97790329_97790704 0.40 ENSG00000223053
.
184419
0.03

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of BARHL2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4 1.3 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.4 1.1 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 0.9 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.3 0.9 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.3 1.2 GO:0043589 skin morphogenesis(GO:0043589)
0.3 0.9 GO:0060437 lung growth(GO:0060437)
0.3 0.8 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.3 0.8 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.3 0.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 0.7 GO:0001778 plasma membrane repair(GO:0001778)
0.2 1.6 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.2 0.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 0.9 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.2 0.8 GO:0060013 righting reflex(GO:0060013)
0.2 0.6 GO:0060242 contact inhibition(GO:0060242)
0.2 0.7 GO:0070141 response to UV-A(GO:0070141)
0.2 0.5 GO:1904747 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.2 0.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.5 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.2 0.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.7 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.2 0.3 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.2 0.5 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.2 0.9 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.2 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 1.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.4 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.5 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1 0.4 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.4 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.3 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.4 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.4 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 2.5 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.4 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 0.7 GO:0016264 gap junction assembly(GO:0016264)
0.1 0.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.4 GO:0010662 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.6 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:0014824 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.3 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.4 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.4 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.4 GO:0008354 germ cell migration(GO:0008354)
0.1 0.2 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.3 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.2 GO:0060677 ureteric bud elongation(GO:0060677)
0.1 0.2 GO:0060206 estrous cycle phase(GO:0060206)
0.1 0.4 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.1 GO:0002246 wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.1 1.2 GO:0030728 ovulation(GO:0030728)
0.1 0.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.1 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:0008347 glial cell migration(GO:0008347)
0.1 0.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.2 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 2.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.2 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.1 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1 0.5 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.1 0.1 GO:0035930 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.1 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.9 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 0.5 GO:0015871 choline transport(GO:0015871)
0.1 0.4 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1 0.2 GO:0060676 ureteric bud formation(GO:0060676)
0.1 0.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.1 0.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.1 GO:0007442 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.1 0.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.2 GO:0042482 positive regulation of odontogenesis(GO:0042482)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 0.1 GO:0061140 lung secretory cell differentiation(GO:0061140)
0.1 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.1 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.6 GO:0035329 hippo signaling(GO:0035329)
0.1 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.1 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.9 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.4 GO:0043113 receptor clustering(GO:0043113)
0.1 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.2 GO:0042640 anagen(GO:0042640)
0.1 0.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.2 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.2 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.1 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.1 GO:0070254 mucus secretion(GO:0070254)
0.1 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718) positive regulation of stem cell differentiation(GO:2000738)
0.0 0.9 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.3 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.9 GO:0014032 neural crest cell development(GO:0014032)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 1.9 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.3 GO:0006241 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.0 GO:0035883 enteroendocrine cell differentiation(GO:0035883)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:0001660 fever generation(GO:0001660)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.0 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.3 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 5.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0060219 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.8 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.6 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0051280 negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.2 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.3 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0060059 female genitalia morphogenesis(GO:0048807) embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.1 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.8 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.0 GO:0060433 bronchus development(GO:0060433) smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0002719 negative regulation of production of molecular mediator of immune response(GO:0002701) negative regulation of cytokine production involved in immune response(GO:0002719)
0.0 0.0 GO:0060004 reflex(GO:0060004)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0 0.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0010092 specification of organ identity(GO:0010092)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.0 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.0 GO:0060571 morphogenesis of an epithelial fold(GO:0060571)
0.0 0.0 GO:0048645 organ formation(GO:0048645)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.0 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.0 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.0 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.2 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.2 GO:0007530 sex determination(GO:0007530)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.2 GO:0007431 salivary gland development(GO:0007431)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.0 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.1 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.2 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.0 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.1 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.3 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.3 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.0 GO:0060192 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0 0.0 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.2 GO:0051923 sulfation(GO:0051923)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.0 GO:0097035 regulation of membrane lipid distribution(GO:0097035)
0.0 0.2 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.0 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:0042723 thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.2 GO:0046068 cGMP metabolic process(GO:0046068)
0.0 0.0 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.0 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.2 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.0 GO:0060405 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0007619 courtship behavior(GO:0007619)
0.0 0.0 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.0 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.0 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.0 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.0 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0021549 cerebellum development(GO:0021549)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0060674 placenta blood vessel development(GO:0060674)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.6 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.0 GO:0071437 invadopodium(GO:0071437)
0.2 0.4 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 0.5 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 0.5 GO:0043259 laminin-10 complex(GO:0043259)
0.2 0.5 GO:0070852 cell body fiber(GO:0070852)
0.2 1.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.6 GO:0005915 zonula adherens(GO:0005915)
0.1 0.5 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.6 GO:0005581 collagen trimer(GO:0005581)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0032982 myosin filament(GO:0032982)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 2.2 GO:0034704 calcium channel complex(GO:0034704)
0.1 0.5 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.1 GO:0045178 basal part of cell(GO:0045178)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.2 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 3.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 10.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0044215 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.9 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.4 GO:0030016 myofibril(GO:0030016)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0036126 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 2.0 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.0 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.5 1.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.2 1.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.6 GO:0070052 collagen V binding(GO:0070052)
0.2 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 1.2 GO:0017166 vinculin binding(GO:0017166)
0.2 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.5 GO:0004470 malic enzyme activity(GO:0004470)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.9 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.5 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.4 GO:0042805 actinin binding(GO:0042805)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 3.4 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.1 GO:0043498 obsolete cell surface binding(GO:0043498)
0.1 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.3 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.8 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.1 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 3.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0035198 miRNA binding(GO:0035198)
0.1 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.2 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.3 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.3 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.0 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 4.3 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 1.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.0 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.0 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0015368 calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 PID SHP2 PATHWAY SHP2 signaling
0.1 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 4.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 6.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 4.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.3 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.0 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.7 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane