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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for BARX1

Z-value: 1.90

Motif logo

Transcription factors associated with BARX1

Gene Symbol	Gene ID	Gene Info
BARX1 Ensembl NCBI GeneCards UniProt	ENSG00000131668.9	BARX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
BARX1	chr9_96713979_96714204	1622	0.487330	0.87	2.6e-03	Click!
BARX1	chr9_96713134_96713760	2266	0.397981	0.80	9.3e-03	Click!
BARX1	chr9_96721839_96721990	4260	0.301469	0.62	7.8e-02	Click!
BARX1	chr9_96712972_96713123	2666	0.365524	0.55	1.3e-01	Click!
BARX1	chr9_96707778_96707962	7843	0.272634	-0.48	1.9e-01	Click!

Activity of the BARX1 motif across conditions

Conditions sorted by the z-value of the BARX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_88857237_88857388	0.81	EPHA3	EPH receptor A3	299362	0.01
chr2_109238478_109238884	0.78	LIMS1	LIM and senescent cell antigen-like domains 1	959	0.64
chr5_167068126_167068277	0.68	CTB-78F1.1		19285	0.25
chr7_55055085_55055236	0.66	EGFR	epidermal growth factor receptor	31554	0.23
chr9_4865980_4866131	0.62	AL158147.2	HCG2011465; Uncharacterized protein	6795	0.16
chr4_153022445_153022684	0.62	ENSG00000266244	.	127056	0.05
chr9_14180576_14180727	0.62	NFIB	nuclear factor I/B	140	0.98
chr11_14375529_14375805	0.61	RRAS2	related RAS viral (r-ras) oncogene homolog 2	379	0.91
chr2_9348603_9349207	0.60	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	2011	0.46
chr10_22908844_22909013	0.59	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	28286	0.24
chr11_115190147_115190298	0.58	CADM1	cell adhesion molecule 1	32025	0.23
chr6_54583337_54583488	0.58	ENSG00000251946	.	67773	0.13
chr15_93429972_93430811	0.58	CHD2	chromodomain helicase DNA binding protein 2	3865	0.22
chr9_100204368_100204519	0.57	TDRD7	tudor domain containing 7	26234	0.18
chr1_193154702_193155811	0.57	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	528	0.8
chr17_26435259_26435410	0.57	ENSG00000252283	.	46341	0.11
chr12_85768780_85768931	0.57	ALX1	ALX homeobox 1	94970	0.09
chr6_98415844_98415995	0.56	ENSG00000238367	.	56488	0.18
chr9_114506322_114506473	0.55	C9orf84	chromosome 9 open reading frame 84	15416	0.21
chr7_38802489_38802640	0.55	VPS41	vacuolar protein sorting 41 homolog (S. cerevisiae)	17402	0.26
chr3_129468296_129468447	0.55	TMCC1	transmembrane and coiled-coil domain family 1	44888	0.13
chr7_113054663_113054814	0.53	TSRM	Uncharacterized protein; Zinc finger domain-related protein TSRM	36389	0.24
chr18_29033854_29034005	0.53	DSG3	desmoglein 3	6171	0.18
chr12_110720958_110721647	0.52	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	1816	0.41
chr12_12713441_12714066	0.51	DUSP16	dual specificity phosphatase 16	258	0.94
chr18_30310087_30311054	0.51	AC012123.1	Uncharacterized protein	39188	0.17
chr5_17695343_17695494	0.51	ENSG00000201715	.	349693	0.01
chr3_150919418_150919700	0.51	GPR171	G protein-coupled receptor 171	1420	0.35
chr14_99726303_99726510	0.51	AL109767.1		2879	0.29
chr8_87505361_87505512	0.51	RMDN1	regulator of microtubule dynamics 1	6637	0.2
chr3_45986008_45986159	0.50	CXCR6	chemokine (C-X-C motif) receptor 6	428	0.8
chr6_37410160_37410312	0.50	CMTR1	cap methyltransferase 1	9240	0.22
chr10_121351719_121352411	0.49	TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	3942	0.27
chr2_202098878_202099103	0.49	CASP8	caspase 8, apoptosis-related cysteine peptidase	761	0.65
chr20_39677452_39677945	0.49	TOP1	topoisomerase (DNA) I	20240	0.19
chr5_142775880_142776681	0.49	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	4137	0.35
chr20_19960279_19960430	0.48	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	37406	0.16
chr3_49447935_49448923	0.47	RHOA	ras homolog family member A	932	0.32
chr9_26262415_26262566	0.47	ENSG00000266429	.	351633	0.01
chr18_61555988_61556228	0.46	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	1115	0.49
chr4_36244695_36244948	0.46	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	740	0.5
chr11_104939544_104939695	0.46	CARD16	caspase recruitment domain family, member 16	23516	0.15
chr5_57134719_57134870	0.46	ENSG00000266864	.	34079	0.24
chr5_77901409_77901560	0.45	LHFPL2	lipoma HMGIC fusion partner-like 2	43164	0.21
chr12_18841597_18841748	0.45	PLCZ1	phospholipase C, zeta 1	6299	0.25
chr4_95455492_95455643	0.45	PDLIM5	PDZ and LIM domain 5	10691	0.32
chr18_19866097_19866248	0.45	ENSG00000238907	.	25633	0.19
chr2_225672771_225672922	0.44	DOCK10	dedicator of cytokinesis 10	8523	0.32
chr3_15482302_15482608	0.44	EAF1-AS1	EAF1 antisense RNA 1	354	0.48
chr21_42217520_42217671	0.44	DSCAM	Down syndrome cell adhesion molecule	1470	0.57
chr6_35568962_35570321	0.44	ENSG00000212579	.	49954	0.1
chr4_68636095_68636246	0.44	GNRHR	gonadotropin-releasing hormone receptor	16092	0.17
chr21_30007689_30007840	0.44	ENSG00000251894	.	107766	0.07
chr1_146744960_146745127	0.44	CHD1L	chromodomain helicase DNA binding protein 1-like	30687	0.17
chr6_17968055_17968324	0.44	KIF13A	kinesin family member 13A	19505	0.26
chr2_227664983_227665444	0.43	IRS1	insulin receptor substrate 1	738	0.67
chr8_130798084_130798335	0.43	GSDMC	gasdermin C	925	0.65
chr1_19946862_19947013	0.43	NBL1	neuroblastoma 1, DAN family BMP antagonist	20111	0.12
chr2_67979592_67979743	0.43	C1D	C1D nuclear receptor corepressor	310447	0.01
chr20_14900011_14900162	0.42	MACROD2-AS1	MACROD2 antisense RNA 1	10046	0.23
chr4_177931083_177931234	0.42	ENSG00000222859	.	171438	0.03
chr2_102359188_102359339	0.42	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	44271	0.19
chr17_70027036_70027208	0.42	AC007461.1	Uncharacterized protein	9042	0.31
chr5_171708618_171708769	0.42	UBTD2	ubiquitin domain containing 2	2382	0.24
chr2_225543043_225543293	0.42	CUL3	cullin 3	93058	0.09
chr7_146801682_146801833	0.41	AC006004.1		7056	0.34
chr9_98271579_98272224	0.41	PTCH1	patched 1	958	0.5
chr4_23891941_23892219	0.41	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	380	0.92
chr3_27765284_27765702	0.41	EOMES	eomesodermin	1287	0.62
chr6_106546757_106547354	0.41	PRDM1	PR domain containing 1, with ZNF domain	240	0.87
chr3_152882551_152883169	0.40	RAP2B	RAP2B, member of RAS oncogene family	2831	0.27
chr8_128492794_128493088	0.40	CASC8	cancer susceptibility candidate 8 (non-protein coding)	1443	0.55
chr2_80853656_80853807	0.40	AC008067.2		7829	0.33
chr20_49136153_49136645	0.40	PTPN1	protein tyrosine phosphatase, non-receptor type 1	9479	0.17
chr20_22384501_22385014	0.40	FOXA2	forkhead box A2	180344	0.03
chr13_69362141_69362292	0.40	ENSG00000243671	.	94003	0.1
chr6_143166734_143167607	0.40	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	8986	0.29
chr2_26100038_26101197	0.40	ASXL2	additional sex combs like 2 (Drosophila)	718	0.76
chr2_212075227_212075378	0.40	ENSG00000199585	.	325076	0.01
chr13_67288038_67288189	0.40	ENSG00000238500	.	83205	0.1
chr22_46479348_46479691	0.40	FLJ27365	hsa-mir-4763	2364	0.16
chr5_161029467_161029618	0.40	GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	54309	0.15
chr3_141863832_141863983	0.39	ENSG00000206604	.	389	0.86
chr8_3895820_3895971	0.39	ENSG00000222546	.	337881	0.01
chrX_121021648_121021799	0.39	ENSG00000221217	.	19003	0.3
chr3_168442261_168442412	0.39	ENSG00000207717	.	172694	0.04
chr13_27998970_27999636	0.39	GTF3A	general transcription factor IIIA	622	0.69
chr9_14310516_14310667	0.39	NFIB	nuclear factor I/B	2579	0.35
chr11_122292174_122292454	0.39	ENSG00000252776	.	27604	0.19
chr14_60646636_60646787	0.39	DHRS7	dehydrogenase/reductase (SDR family) member 7	10137	0.22
chr1_13913631_13913782	0.38	PDPN	podoplanin	1739	0.34
chr15_93999319_93999470	0.38	ENSG00000212063	.	169842	0.04
chr14_99731258_99732023	0.38	AL109767.1		2355	0.32
chr5_26332801_26332952	0.38	ENSG00000222560	.	319878	0.01
chr20_11882046_11882285	0.38	BTBD3	BTB (POZ) domain containing 3	9024	0.24
chr14_37921365_37921516	0.38	ENSG00000207046	.	17662	0.26
chr2_214003351_214003502	0.38	IKZF2	IKAROS family zinc finger 2 (Helios)	9927	0.3
chr7_38802308_38802459	0.38	VPS41	vacuolar protein sorting 41 homolog (S. cerevisiae)	17221	0.26
chr1_116222239_116222390	0.38	VANGL1	VANGL planar cell polarity protein 1	28291	0.19
chr10_80549668_80549819	0.38	ENSG00000223243	.	39384	0.22
chr13_105245098_105245249	0.38	DAOA	D-amino acid oxidase activator	873419	0.0
chr9_10292066_10292217	0.38	PTPRD	protein tyrosine phosphatase, receptor type, D	258351	0.02
chr9_103190951_103191277	0.38	MSANTD3	Myb/SANT-like DNA-binding domain containing 3	1395	0.38
chr7_113453360_113453511	0.37	PPP1R3A	protein phosphatase 1, regulatory subunit 3A	105685	0.08
chr2_169381166_169381317	0.37	ENSG00000265694	.	58212	0.11
chr16_27590300_27590451	0.37	KIAA0556	KIAA0556	5147	0.22
chr5_132148673_132149114	0.37	SOWAHA	sosondowah ankyrin repeat domain family member A	140	0.93
chr6_121630791_121630942	0.37	TBC1D32	TBC1 domain family, member 32	24710	0.19
chr1_94089405_94089556	0.37	BCAR3	breast cancer anti-estrogen resistance 3	9826	0.22
chr10_6534786_6534937	0.37	PRKCQ	protein kinase C, theta	87340	0.09
chr7_870647_870798	0.37	SUN1	Sad1 and UNC84 domain containing 1	155	0.95
chr12_47474612_47474997	0.37	AMIGO2	adhesion molecule with Ig-like domain 2	1070	0.46
chr5_78533787_78534060	0.37	JMY	junction mediating and regulatory protein, p53 cofactor	1911	0.32
chr4_77361001_77361152	0.37	SHROOM3	shroom family member 3	4823	0.19
chr13_69182775_69182926	0.37	ENSG00000243671	.	85363	0.11
chr3_189932576_189932727	0.36	ENSG00000212489	.	49339	0.13
chr2_161055572_161055723	0.36	ITGB6	integrin, beta 6	1116	0.65
chr10_105842771_105842922	0.36	COL17A1	collagen, type XVII, alpha 1	2690	0.25
chr7_55638778_55639418	0.36	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	463	0.8
chr11_1594767_1594941	0.36	KRTAP5-AS1	KRTAP5-1/KRTAP5-2 antisense RNA 1	25	0.95
chr12_54393540_54393854	0.36	HOXC-AS1	HOXC cluster antisense RNA 1	97	0.62
chr2_511397_511548	0.36	TMEM18	transmembrane protein 18	164303	0.03
chr8_66751756_66751954	0.36	PDE7A	phosphodiesterase 7A	872	0.73
chr21_19184526_19184677	0.36	AL109761.5		3339	0.27
chr3_9211616_9211767	0.36	SRGAP3-AS2	SRGAP3 antisense RNA 2	22486	0.19
chr18_74781332_74781483	0.36	MBP	myelin basic protein	35810	0.21
chr18_74535928_74536174	0.36	ZNF236	zinc finger protein 236	65	0.97
chr3_160940288_160940439	0.36	NMD3	NMD3 ribosome export adaptor	1016	0.69
chr1_24513240_24513925	0.36	IFNLR1	interferon, lambda receptor 1	156	0.95
chr13_19683905_19684056	0.36	ENSG00000252287	.	21353	0.16
chr10_24544633_24544808	0.36	KIAA1217	KIAA1217	463	0.87
chr11_45954841_45954992	0.36	PHF21A	PHD finger protein 21A	3142	0.17
chr13_97927308_97927620	0.36	MBNL2	muscleblind-like splicing regulator 2	994	0.69
chr2_121200095_121200392	0.35	LINC01101	long intergenic non-protein coding RNA 1101	23454	0.24
chr8_22299319_22300279	0.35	PPP3CC	protein phosphatase 3, catalytic subunit, gamma isozyme	921	0.52
chr4_184462117_184462317	0.35	ING2	inhibitor of growth family, member 2	34857	0.13
chr5_123535811_123535962	0.35	RP11-436H11.2		528638	0.0
chr11_67978844_67978995	0.35	SUV420H1	suppressor of variegation 4-20 homolog 1 (Drosophila)	1302	0.47
chr5_127036963_127037114	0.35	CTC-548H10.2		37317	0.19
chr5_36951473_36951624	0.35	NIPBL	Nipped-B homolog (Drosophila)	74656	0.12
chr2_237994859_237995202	0.35	COPS8	COP9 signalosome subunit 8	444	0.55
chr5_77702587_77702738	0.35	SCAMP1	secretory carrier membrane protein 1	46323	0.16
chr1_200865204_200865355	0.35	C1orf106	chromosome 1 open reading frame 106	1330	0.42
chr2_165752618_165752769	0.35	ENSG00000223318	.	406	0.84
chr5_102098307_102098531	0.35	PAM	peptidylglycine alpha-amidating monooxygenase	7372	0.33
chr10_5753060_5753327	0.35	RP11-336A10.2		3193	0.23
chr2_235401897_235402222	0.35	ARL4C	ADP-ribosylation factor-like 4C	3185	0.41
chr4_109091401_109091552	0.35	LEF1	lymphoid enhancer-binding factor 1	1364	0.38
chr11_131504053_131504367	0.35	NTM	neurotrimin	26678	0.22
chr2_106473228_106473435	0.35	AC009505.2		129	0.97
chr20_56950629_56950814	0.35	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	13457	0.22
chr17_76531597_76531748	0.35	ENSG00000243426	.	2535	0.25
chr4_37162096_37162247	0.34	ENSG00000264319	.	81442	0.1
chr12_73927280_73927431	0.34	ENSG00000252415	.	145721	0.05
chr5_50681604_50681755	0.34	ISL1	ISL LIM homeobox 1	2173	0.32
chr13_27742496_27742673	0.34	USP12	ubiquitin specific peptidase 12	3449	0.18
chr20_8042110_8042261	0.34	RP5-971N18.3		38912	0.16
chr10_25138176_25138392	0.34	ENSG00000240294	.	59457	0.13
chr5_104399872_104400023	0.34	ENSG00000252881	.	283857	0.01
chr1_155971887_155972038	0.34	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	4899	0.11
chr7_158609578_158609780	0.34	ESYT2	extended synaptotagmin-like protein 2	12484	0.24
chr1_215744331_215744482	0.34	KCTD3	potassium channel tetramerization domain containing 3	2723	0.39
chr2_19551253_19551447	0.34	ENSG00000266738	.	3160	0.31
chr13_24345953_24346104	0.34	MIPEP	mitochondrial intermediate peptidase	11316	0.22
chr5_112630315_112630670	0.34	MCC	mutated in colorectal cancers	154	0.97
chr10_77649296_77649447	0.34	ENSG00000215921	.	65835	0.13
chr12_85410552_85410703	0.34	TSPAN19	tetraspanin 19	747	0.74
chr9_128512257_128512408	0.34	PBX3	pre-B-cell leukemia homeobox 3	1854	0.45
chr12_64481061_64481212	0.33	RP11-196H14.2		10262	0.2
chr3_29394543_29394694	0.33	ENSG00000216169	.	16294	0.25
chr9_33446798_33447442	0.33	AQP3	aquaporin 3 (Gill blood group)	489	0.76
chr2_242227382_242227533	0.33	HDLBP	high density lipoprotein binding protein	14682	0.14
chr13_56905088_56905239	0.33	ENSG00000238455	.	228595	0.02
chr4_181237914_181238065	0.33	NA	NA	> 10⁶	NA
chr15_64888931_64889431	0.33	ENSG00000207223	.	55906	0.09
chr15_48163115_48163266	0.33	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	104413	0.07
chr5_105827510_105827661	0.33	ENSG00000252337	.	54781	0.19
chr5_30522530_30522681	0.33	ENSG00000223136	.	573670	0.0
chr7_24576141_24576292	0.33	ENSG00000206877	.	735	0.75
chr5_162930555_162931177	0.33	MAT2B	methionine adenosyltransferase II, beta	746	0.62
chr2_206543328_206543479	0.33	NRP2	neuropilin 2	3821	0.34
chr5_141952328_141952479	0.33	AC005592.2		9010	0.22
chr3_30655384_30655643	0.33	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	7420	0.31
chr13_45782351_45782502	0.33	KCTD4	potassium channel tetramerization domain containing 4	7251	0.2
chr19_34717882_34718033	0.33	KIAA0355	KIAA0355	27485	0.19
chr6_69869443_69869594	0.33	ENSG00000265498	.	55184	0.16
chr7_55955661_55956073	0.33	MRPS17	28S ribosomal protein S17, mitochondrial; HCG1984214, isoform CRA_a	897	0.5
chr1_167165756_167165907	0.33	RP11-277B15.2		802	0.62
chr14_22964398_22964682	0.33	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	8369	0.1
chr14_99681447_99681708	0.33	AL109767.1		47708	0.14
chr1_189407668_189407819	0.33	ENSG00000252553	.	227643	0.02
chr18_61445658_61445809	0.33	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	522	0.82
chr3_60921693_60921844	0.33	ENSG00000212211	.	79491	0.12
chr13_24162891_24163042	0.33	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	9447	0.29
chr12_80746852_80747003	0.33	OTOGL	otogelin-like	3207	0.28
chr4_143488982_143489737	0.33	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	7537	0.34
chr7_20825937_20826584	0.32	SP8	Sp8 transcription factor	245	0.96
chr10_35090167_35090318	0.32	PARD3	par-3 family cell polarity regulator	14007	0.22
chr13_71667523_71667674	0.32	ENSG00000202433	.	634002	0.0
chr2_21445047_21445198	0.32	TDRD15	tudor domain containing 15	98333	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BARX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.2	0.5	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.4	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.4	GO:0061117	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1	0.4	GO:0060426	lung vasculature development(GO:0060426)
0.1	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.4	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.2	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.4	GO:1900121	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1	0.3	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1	0.6	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.6	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.1	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.3	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.4	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.3	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.3	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.3	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.3	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.3	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.2	GO:0070295	renal water absorption(GO:0070295)
0.1	0.2	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.1	0.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.5	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1	0.3	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.1	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.2	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.2	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.1	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1	0.5	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.5	GO:0043383	negative T cell selection(GO:0043383)
0.1	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.1	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) renal vesicle morphogenesis(GO:0072077) renal vesicle development(GO:0072087) metanephric renal vesicle morphogenesis(GO:0072283)
0.1	0.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.1	0.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.2	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.2	GO:0033088	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.2	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.3	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	0.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.1	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.1	0.1	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	0.7	GO:0030260	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1	0.1	GO:0060435	bronchiole development(GO:0060435)
0.1	0.5	GO:0048841	regulation of axon extension involved in axon guidance(GO:0048841)
0.1	0.2	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.1	0.5	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.6	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.4	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.2	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.3	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.2	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.3	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.2	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.2	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.0	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.2	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.2	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.3	GO:0071326	cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.2	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.1	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.8	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.2	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.2	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.4	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:2000794	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.0	GO:0044557	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.2	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.2	GO:1901862	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.2	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.2	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.3	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0002098	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.5	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.0	GO:0060856	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009) establishment of blood-brain barrier(GO:0060856)
0.0	0.1	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0043921	modulation by host of viral transcription(GO:0043921) negative regulation by host of viral transcription(GO:0043922) modulation by host of symbiont transcription(GO:0052472)
0.0	0.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.2	GO:0010510	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.4	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.0	GO:0006949	syncytium formation(GO:0006949)
0.0	0.3	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.1	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.2	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0010894	negative regulation of steroid biosynthetic process(GO:0010894)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.0	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.3	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.1	GO:0046831	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0021591	ventricular system development(GO:0021591)
0.0	0.2	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.0	GO:0002860	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.0	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.1	GO:0043137	lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.2	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.0	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.0	GO:0060510	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0	0.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.3	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835) negative regulation of protein depolymerization(GO:1901880)
0.0	0.4	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0035089	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0046902	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.0	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:1901222	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.0	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.5	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.3	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:1901796	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) regulation of signal transduction by p53 class mediator(GO:1901796)
0.0	0.2	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.1	GO:0034644	cellular response to UV(GO:0034644)
0.0	0.6	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.6	GO:0006921	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.0	GO:2000826	regulation of heart morphogenesis(GO:2000826)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0017004	cytochrome complex assembly(GO:0017004)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0002209	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.0	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0072178	nephric duct morphogenesis(GO:0072178)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.3	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.3	GO:0007569	cell aging(GO:0007569)
0.0	0.0	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.0	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.1	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.0	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.5	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.1	GO:0071437	invadopodium(GO:0071437)
0.1	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.5	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.9	GO:0030057	desmosome(GO:0030057)
0.0	0.3	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.3	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.7	GO:0055037	recycling endosome(GO:0055037)
0.0	0.6	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0070062	extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	1.5	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	1.3	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:1904949	ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.3	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.6	GO:0034707	chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.5	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.4	GO:0043559	insulin binding(GO:0043559)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.3	GO:0005113	patched binding(GO:0005113)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.2	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	1.1	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.2	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.2	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1	0.2	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1	0.5	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.5	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.7	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.3	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.1	0.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.4	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.5	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.3	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.5	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.4	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.2	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.7	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.2	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.3	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.4	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.3	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.2	GO:0035004	phosphatidylinositol 3-kinase activity(GO:0035004)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.2	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.2	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.4	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.2	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.0	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.2	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.2	GO:0051117	ATPase binding(GO:0051117)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.3	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.3	GO:0000049	tRNA binding(GO:0000049)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.0	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.3	GO:0045296	cadherin binding(GO:0045296)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.0	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.0	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	1.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.6	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.2	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.2	PID FGF PATHWAY	FGF signaling pathway
0.0	1.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	PID BMP PATHWAY	BMP receptor signaling
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	0.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.7	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	1.0	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.5	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.5	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER