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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for BBX

Z-value: 1.79

Motif logo

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Transcription factors associated with BBX

Gene Symbol Gene ID Gene Info
BBX
ENSG00000114439.14 BBX high mobility group box domain containing

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr3_107381179_107381566BBX640.987673-0.665.1e-02Click!
chr3_107244861_107245089BBX7260.804364-0.511.6e-01Click!
chr3_107243761_107243927BBX3940.921629-0.501.7e-01Click!
chr3_107564740_107564985BBX474240.197769-0.501.7e-01Click!
chr3_107380658_107381123BBX5460.876237-0.491.8e-01Click!

Activity of the BBX motif across conditions

Conditions sorted by the z-value of the BBX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_148189087_148189390 1.15 ADRB2
 adrenoceptor beta 2, surface
 16918
 0.25
chr2_143887583_143887860 1.07 ARHGAP15
 Rho GTPase activating protein 15
 838
 0.72
chr3_16329316_16329467 0.85 OXNAD1
 oxidoreductase NAD-binding domain containing 1
 18643
 0.15
chr8_133771865_133772108 0.85 TMEM71
 transmembrane protein 71
 808
 0.63
chr12_15109499_15109902 0.83 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
 4500
 0.19
chr13_99957828_99957979 0.83 GPR183
 G protein-coupled receptor 183
 1756
 0.38
chr10_6103670_6104125 0.82 IL2RA
 interleukin 2 receptor, alpha
 356
 0.84
chr2_235362717_235362976 0.81 ARL4C
 ADP-ribosylation factor-like 4C
 42398
 0.22
chr7_150148744_150149359 0.75 GIMAP8
 GTPase, IMAP family member 8
 1333
 0.41
chr14_22695818_22695969 0.74 ENSG00000238634
 .
 85006
 0.09
chr16_81031171_81031400 0.73 CMC2
 C-x(9)-C motif containing 2
 979
 0.45
chr7_156761668_156761819 0.69 NOM1
 nucleolar protein with MIF4G domain 1
 19326
 0.16
chr7_150217655_150217806 0.69 GIMAP7
 GTPase, IMAP family member 7
 5812
 0.21
chr13_74807691_74807851 0.69 ENSG00000206617
 .
 55580
 0.16
chr19_2892956_2893107 0.69 ZNF57
 zinc finger protein 57
 7865
 0.11
chr2_196122609_196122760 0.67 ENSG00000202206
 .
 256076
 0.02
chr21_40139305_40139870 0.67 ETS2
 v-ets avian erythroblastosis virus E26 oncogene homolog 2
 37644
 0.21
chr7_50349443_50349694 0.66 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 1250
 0.61
chr6_139459897_139460408 0.66 HECA
 headcase homolog (Drosophila)
 3903
 0.31
chr1_198609761_198609912 0.66 PTPRC
 protein tyrosine phosphatase, receptor type, C
 1544
 0.48
chr12_67107724_67108271 0.65 GRIP1
 glutamate receptor interacting protein 1
 35072
 0.24
chr17_37933203_37933446 0.65 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 1154
 0.4
chr7_50345819_50346403 0.64 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 1733
 0.5
chr2_68963544_68963853 0.64 ARHGAP25
 Rho GTPase activating protein 25
 1684
 0.46
chr20_62270981_62271132 0.63 CTD-3184A7.4
12453
 0.09
chr10_127687165_127687316 0.63 FANK1
 fibronectin type III and ankyrin repeat domains 1
 3254
 0.27
chr18_21573835_21574026 0.63 TTC39C
 tetratricopeptide repeat domain 39C
 1193
 0.47
chr1_186292481_186292673 0.63 ENSG00000202025
 .
 11517
 0.17
chr12_4385782_4386106 0.62 CCND2-AS1
 CCND2 antisense RNA 1
 594
 0.46
chr10_111836950_111837776 0.62 ADD3
 adducin 3 (gamma)
 69641
 0.1
chr7_150146102_150146542 0.61 GIMAP8
 GTPase, IMAP family member 8
 1396
 0.39
chr21_35305474_35305968 0.60 LINC00649
 long intergenic non-protein coding RNA 649
 2203
 0.25
chr5_110561342_110561544 0.60 CAMK4
 calcium/calmodulin-dependent protein kinase IV
 1659
 0.44
chr1_239881158_239881438 0.57 ENSG00000233355
 .
 1068
 0.49
chr14_22948566_22948717 0.57 ENSG00000251002
 .
 1637
 0.2
chr7_50415328_50415483 0.57 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 48160
 0.16
chr17_29637369_29637894 0.57 EVI2B
 ecotropic viral integration site 2B
 3471
 0.16
chr1_198610920_198611071 0.56 PTPRC
 protein tyrosine phosphatase, receptor type, C
 2703
 0.34
chr14_38558504_38558837 0.56 CTD-2058B24.2
1693
 0.48
chr5_56125291_56125578 0.56 MAP3K1
 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
 14033
 0.16
chr7_142429480_142429631 0.55 PRSS1
 protease, serine, 1 (trypsin 1)
 27764
 0.17
chr6_106970433_106970694 0.55 AIM1
 absent in melanoma 1
 10833
 0.2
chr4_40202894_40203061 0.54 RHOH
 ras homolog family member H
 1013
 0.59
chr17_38018967_38019134 0.54 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 1329
 0.36
chr3_121373349_121373500 0.53 ENSG00000243544
 .
 281
 0.82
chr1_111417492_111418003 0.52 CD53
 CD53 molecule
 1971
 0.34
chr5_96294037_96294231 0.52 LNPEP
 leucyl/cystinyl aminopeptidase
 21
 0.98
chr2_199271076_199271227 0.51 ENSG00000252511
 .
 160302
 0.04
chr1_101706338_101706489 0.51 RP4-575N6.5
2301
 0.23
chr14_88472278_88472651 0.50 GPR65
 G protein-coupled receptor 65
 996
 0.51
chr17_38716835_38717173 0.50 CCR7
 chemokine (C-C motif) receptor 7
 261
 0.91
chr10_65033773_65033924 0.49 JMJD1C
 jumonji domain containing 1C
 4866
 0.31
chr7_50345445_50345596 0.49 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 1142
 0.64
chr1_169672728_169672969 0.48 SELL
 selectin L
 7991
 0.2
chr12_47611625_47611801 0.48 PCED1B
 PC-esterase domain containing 1B
 1332
 0.49
chr3_151916550_151916780 0.47 MBNL1
 muscleblind-like splicing regulator 1
 69164
 0.11
chr19_3136242_3137376 0.47 GNA15
 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
 618
 0.58
chr3_151922152_151922513 0.47 MBNL1
 muscleblind-like splicing regulator 1
 63497
 0.12
chr10_8179903_8180054 0.47 GATA3
 GATA binding protein 3
 83209
 0.11
chr1_192546230_192546423 0.46 RGS1
 regulator of G-protein signaling 1
 1423
 0.45
chr2_225809390_225809894 0.46 DOCK10
 dedicator of cytokinesis 10
 2140
 0.45
chr10_62487545_62487752 0.46 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 5600
 0.3
chr11_118178183_118178334 0.46 CD3E
 CD3e molecule, epsilon (CD3-TCR complex)
 2644
 0.19
chrX_51545134_51545285 0.46 MAGED1
 melanoma antigen family D, 1
 894
 0.68
chr3_85786117_85786268 0.45 CADM2
 cell adhesion molecule 2
 10560
 0.3
chr11_117873682_117873833 0.45 IL10RA
 interleukin 10 receptor, alpha
 16648
 0.17
chr13_46755525_46755771 0.45 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 811
 0.58
chr4_11473602_11473900 0.45 HS3ST1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
 42362
 0.18
chr6_106968393_106968700 0.45 AIM1
 absent in melanoma 1
 8816
 0.21
chr13_24826594_24826745 0.45 SPATA13
 spermatogenesis associated 13
 813
 0.56
chr14_100532787_100533367 0.44 EVL
 Enah/Vasp-like
 303
 0.88
chr20_51618499_51618650 0.44 TSHZ2
 teashirt zinc finger homeobox 2
 29628
 0.21
chr2_158274562_158274945 0.44 CYTIP
 cytohesin 1 interacting protein
 21173
 0.2
chr1_102637571_102637722 0.44 OLFM3
 olfactomedin 3
 175060
 0.04
chr1_198624965_198625116 0.44 RP11-553K8.5
11150
 0.23
chr2_26045186_26045754 0.44 ASXL2
 additional sex combs like 2 (Drosophila)
 42292
 0.17
chr7_38389675_38390189 0.43 AMPH
 amphiphysin
 112781
 0.07
chr11_94960734_94960891 0.43 RP11-712B9.2
2538
 0.31
chr5_156616823_156617066 0.43 ITK
 IL2-inducible T-cell kinase
 9107
 0.13
chr4_143488164_143488362 0.43 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 6441
 0.35
chr14_22958589_22958740 0.43 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 2493
 0.16
chr2_158299271_158299480 0.43 CYTIP
 cytohesin 1 interacting protein
 1279
 0.38
chr5_35859051_35859218 0.42 IL7R
 interleukin 7 receptor
 2140
 0.33
chr5_156610422_156610951 0.42 ITK
 IL2-inducible T-cell kinase
 2849
 0.18
chrX_13680096_13680380 0.42 TCEANC
 transcription elongation factor A (SII) N-terminal and central domain containing
 6824
 0.2
chr6_35271134_35271290 0.42 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 5583
 0.2
chr2_68961577_68961872 0.42 ARHGAP25
 Rho GTPase activating protein 25
 189
 0.96
chr17_29644174_29644325 0.42 CTD-2370N5.3
1409
 0.29
chr1_167483926_167484083 0.42 CD247
 CD247 molecule
 3771
 0.25
chr5_148727072_148727373 0.42 GRPEL2
 GrpE-like 2, mitochondrial (E. coli)
 2157
 0.2
chr2_197033507_197033658 0.42 STK17B
 serine/threonine kinase 17b
 2142
 0.32
chr5_103563842_103563993 0.41 ENSG00000239808
 .
 32610
 0.25
chr10_11213825_11214053 0.41 RP3-323N1.2
600
 0.77
chr1_32719471_32719691 0.41 LCK
 lymphocyte-specific protein tyrosine kinase
 2706
 0.13
chr12_19375312_19375463 0.41 PLEKHA5
 pleckstrin homology domain containing, family A member 5
 14471
 0.22
chr2_99346083_99347252 0.40 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
 44
 0.98
chr2_68978993_68979334 0.40 ARHGAP25
 Rho GTPase activating protein 25
 17149
 0.23
chr6_133084105_133084393 0.40 VNN2
 vanin 2
 321
 0.83
chr14_22771842_22772128 0.40 ENSG00000251002
 .
 129734
 0.04
chr6_26361253_26361404 0.40 BTN3A2
 butyrophilin, subfamily 3, member A2
 4059
 0.11
chr6_32556246_32556444 0.40 HLA-DRB1
 major histocompatibility complex, class II, DR beta 1
 1280
 0.36
chr22_40858929_40859404 0.40 MKL1
 megakaryoblastic leukemia (translocation) 1
 256
 0.92
chr20_39676850_39677439 0.39 TOP1
 topoisomerase (DNA) I
 19686
 0.2
chr5_180243457_180243608 0.39 MGAT1
 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
 952
 0.53
chr15_38854702_38854853 0.39 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
 2059
 0.32
chr13_49065972_49066123 0.39 RCBTB2
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
 41166
 0.17
chr18_51245241_51245392 0.39 RP11-671P2.1
150663
 0.05
chr9_88953252_88953465 0.39 ZCCHC6
 zinc finger, CCHC domain containing 6
 4680
 0.26
chr14_42218476_42218627 0.39 LRFN5
 leucine rich repeat and fibronectin type III domain containing 5
 49921
 0.19
chr1_174935570_174935876 0.39 RABGAP1L
 RAB GTPase activating protein 1-like
 1818
 0.28
chr2_158295494_158296053 0.39 CYTIP
 cytohesin 1 interacting protein
 153
 0.96
chr10_6619930_6620081 0.39 PRKCQ
 protein kinase C, theta
 2196
 0.46
chr21_30204766_30204917 0.39 N6AMT1
 N-6 adenine-specific DNA methyltransferase 1 (putative)
 52852
 0.14
chr17_15586451_15586602 0.39 TRIM16
 tripartite motif containing 16
 333
 0.83
chr7_37381509_37381660 0.39 ELMO1
 engulfment and cell motility 1
 783
 0.68
chr1_198590020_198590171 0.39 PTPRC
 protein tyrosine phosphatase, receptor type, C
 17706
 0.23
chr21_36414032_36414216 0.39 RUNX1
 runt-related transcription factor 1
 7338
 0.33
chr13_41556163_41556400 0.38 ELF1
 E74-like factor 1 (ets domain transcription factor)
 137
 0.96
chr1_200859875_200861145 0.38 C1orf106
 chromosome 1 open reading frame 106
 41
 0.97
chrX_12990488_12990859 0.38 TMSB4X
 thymosin beta 4, X-linked
 2554
 0.33
chr6_90813429_90813580 0.38 ENSG00000222078
 .
 102279
 0.07
chr4_83145308_83145459 0.38 ENSG00000202485
 .
 49683
 0.16
chr6_45982477_45982717 0.38 CLIC5
 chloride intracellular channel 5
 968
 0.6
chr6_109223664_109223815 0.38 ARMC2-AS1
 ARMC2 antisense RNA 1
 21567
 0.2
chr1_229461570_229461782 0.38 RP4-803J11.2
6526
 0.15
chr6_144666173_144666513 0.38 UTRN
 utrophin
 1106
 0.59
chr1_9717913_9718080 0.38 C1orf200
 chromosome 1 open reading frame 200
 3352
 0.21
chr14_22887351_22887502 0.38 ENSG00000251002
 .
 14293
 0.12
chr5_56473598_56474064 0.38 GPBP1
 GC-rich promoter binding protein 1
 2058
 0.37
chr1_117301810_117301961 0.37 CD2
 CD2 molecule
 4796
 0.25
chr13_99992298_99992449 0.37 ENSG00000207719
 .
 16012
 0.19
chr8_126960397_126960568 0.37 ENSG00000206695
 .
 47287
 0.2
chr13_41551268_41551419 0.37 ELF1
 E74-like factor 1 (ets domain transcription factor)
 5075
 0.22
chr2_202124822_202124973 0.37 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 326
 0.89
chr16_27415626_27415898 0.37 IL21R
 interleukin 21 receptor
 1339
 0.47
chr10_17705373_17705524 0.37 ENSG00000251959
 .
 15739
 0.14
chr9_128506323_128506474 0.37 PBX3
 pre-B-cell leukemia homeobox 3
 3226
 0.33
chr1_161154335_161154531 0.36 B4GALT3
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
 7146
 0.07
chr2_106413120_106413271 0.36 NCK2
 NCK adaptor protein 2
 19820
 0.25
chr3_53077435_53077586 0.36 SFMBT1
 Scm-like with four mbt domains 1
 1771
 0.34
chr2_41127_41278 0.36 FAM110C
 family with sequence similarity 110, member C
 5183
 0.33
chr15_96422557_96422745 0.36 ENSG00000222076
 .
 133618
 0.06
chr11_94886237_94886421 0.36 RP11-712B9.2
1419
 0.51
chr12_9760101_9760256 0.36 KLRB1
 killer cell lectin-like receptor subfamily B, member 1
 304
 0.86
chr10_28909540_28909691 0.36 ENSG00000252401
 .
 31944
 0.16
chr2_7017776_7018587 0.36 RSAD2
 radical S-adenosyl methionine domain containing 2
 385
 0.85
chr1_29253817_29254129 0.36 EPB41
 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
 12882
 0.18
chr14_22949288_22949494 0.36 ENSG00000251002
 .
 887
 0.35
chr12_59460604_59460755 0.36 RP11-150C16.1
146259
 0.04
chr13_99966619_99966770 0.35 GPR183
 G protein-coupled receptor 183
 7035
 0.21
chr7_142423497_142423648 0.35 PRSS1
 protease, serine, 1 (trypsin 1)
 33747
 0.16
chr2_225734023_225734174 0.35 DOCK10
 dedicator of cytokinesis 10
 52729
 0.18
chr1_193506744_193506895 0.35 ENSG00000252241
 .
 194255
 0.03
chr12_32120805_32121101 0.35 KIAA1551
 KIAA1551
 5530
 0.26
chrX_25812581_25812732 0.35 MAGEB18
 melanoma antigen family B, 18
 343804
 0.01
chr5_97126080_97126231 0.35 CTD-2215E18.2
588571
 0.0
chr10_73844664_73844815 0.35 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 3347
 0.29
chr6_76320868_76321019 0.35 SENP6
 SUMO1/sentrin specific peptidase 6
 9180
 0.17
chr21_19161404_19161758 0.35 AL109761.5
4224
 0.27
chr14_94437286_94437966 0.35 ASB2
 ankyrin repeat and SOCS box containing 2
 2803
 0.22
chr20_47436352_47436503 0.35 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 7993
 0.28
chr14_22636757_22636908 0.35 ENSG00000238634
 .
 25945
 0.24
chr18_32180370_32180521 0.34 DTNA
 dystrobrevin, alpha
 7116
 0.32
chr3_63937239_63937390 0.34 ATXN7
 ataxin 7
 16106
 0.16
chr5_148726870_148727055 0.34 GRPEL2
 GrpE-like 2, mitochondrial (E. coli)
 1897
 0.22
chr1_169672524_169672675 0.34 SELL
 selectin L
 8240
 0.2
chr1_158903283_158903483 0.34 PYHIN1
 pyrin and HIN domain family, member 1
 2025
 0.36
chr7_115555128_115555279 0.34 TFEC
 transcription factor EC
 53101
 0.16
chr1_111745814_111746254 0.34 DENND2D
 DENN/MADD domain containing 2D
 997
 0.41
chr3_112692076_112692299 0.34 CD200R1
 CD200 receptor 1
 1572
 0.33
chr12_118796178_118796667 0.34 TAOK3
 TAO kinase 3
 488
 0.85
chr8_37755503_37755707 0.34 RAB11FIP1
 RAB11 family interacting protein 1 (class I)
 1367
 0.34
chr14_29078339_29078490 0.34 RP11-966I7.1
156055
 0.04
chr3_149419705_149419856 0.34 WWTR1
 WW domain containing transcription regulator 1
 1280
 0.44
chr3_18476194_18476345 0.34 SATB1
 SATB homeobox 1
 476
 0.83
chr3_43331814_43332301 0.34 SNRK
 SNF related kinase
 3979
 0.23
chr14_22972290_22972441 0.34 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 16194
 0.09
chr9_134151798_134152108 0.34 FAM78A
 family with sequence similarity 78, member A
 19
 0.98
chr11_314983_315695 0.34 IFITM1
 interferon induced transmembrane protein 1
 1486
 0.17
chr8_67053974_67054125 0.34 TRIM55
 tripartite motif containing 55
 14771
 0.23
chr14_102291094_102291439 0.33 CTD-2017C7.1
14602
 0.14
chr12_2410862_2411129 0.33 CACNA1C-IT3
 CACNA1C intronic transcript 3 (non-protein coding)
 32053
 0.21
chr1_206718342_206718493 0.33 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 12076
 0.16
chr4_90220151_90220996 0.33 GPRIN3
 GPRIN family member 3
 8588
 0.31
chr1_215313373_215313524 0.33 KCNK2
 potassium channel, subfamily K, member 2
 56588
 0.18
chr4_143488982_143489737 0.32 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 7537
 0.34
chr11_46581548_46581763 0.32 AMBRA1
 autophagy/beclin-1 regulator 1
 31259
 0.15
chr12_113344776_113345099 0.32 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
 80
 0.97
chr14_32672059_32672251 0.32 ENSG00000202337
 .
 320
 0.8
chr3_195265081_195265237 0.32 PPP1R2
 protein phosphatase 1, regulatory (inhibitor) subunit 2
 5017
 0.17
chr5_162935820_162936429 0.32 MAT2B
 methionine adenosyltransferase II, beta
 3504
 0.21
chr11_39392973_39393210 0.32 ENSG00000201591
 .
 110434
 0.08
chr6_25040660_25040811 0.32 RP3-425P12.5
1332
 0.34
chr21_43825650_43825846 0.32 UBASH3A
 ubiquitin associated and SH3 domain containing A
 1722
 0.26
chr11_116802141_116802415 0.32 SIK3
 SIK family kinase 3
 25482
 0.14
chr14_91877157_91877308 0.32 CCDC88C
 coiled-coil domain containing 88C
 6458
 0.25
chr2_204803308_204803520 0.32 ICOS
 inducible T-cell co-stimulator
 1911
 0.46
chr12_98912505_98912656 0.32 TMPO-AS1
 TMPO antisense RNA 1
 2380
 0.2
chr1_111421280_111421431 0.32 CD53
 CD53 molecule
 5579
 0.21
chr1_114413652_114413958 0.32 PTPN22
 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
 515
 0.69

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of BBX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.7 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.4 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1 1.2 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:0002517 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1 0.8 GO:0002836 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1 0.5 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.3 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1 0.3 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 0.2 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.6 GO:0043368 positive T cell selection(GO:0043368)
0.1 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.3 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.1 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 1.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.0 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.2 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.3 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.4 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.0 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.6 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.0 GO:0070897 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.3 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.0 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.0 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.3 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.2 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.8 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.0 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.6 GO:0001892 embryonic placenta development(GO:0001892)
0.0 0.3 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:1904590 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0014824 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.0 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.0 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.0 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.0 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.0 GO:0048617 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.0 GO:0035929 steroid hormone secretion(GO:0035929)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.5 GO:0097194 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.0 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.7 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.7 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 1.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.2 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.5 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.5 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 4.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 2.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.0 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.0 REACTOME S PHASE Genes involved in S Phase
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects