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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for BBX

Z-value: 1.79

Motif logo

Transcription factors associated with BBX

Gene Symbol	Gene ID	Gene Info
BBX Ensembl NCBI GeneCards UniProt	ENSG00000114439.14	BBX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
BBX	chr3_107381179_107381566	64	0.987673	-0.66	5.1e-02	Click!
BBX	chr3_107244861_107245089	726	0.804364	-0.51	1.6e-01	Click!
BBX	chr3_107243761_107243927	394	0.921629	-0.50	1.7e-01	Click!
BBX	chr3_107564740_107564985	47424	0.197769	-0.50	1.7e-01	Click!
BBX	chr3_107380658_107381123	546	0.876237	-0.49	1.8e-01	Click!

Activity of the BBX motif across conditions

Conditions sorted by the z-value of the BBX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_148189087_148189390	1.15	ADRB2	adrenoceptor beta 2, surface	16918	0.25
chr2_143887583_143887860	1.07	ARHGAP15	Rho GTPase activating protein 15	838	0.72
chr3_16329316_16329467	0.85	OXNAD1	oxidoreductase NAD-binding domain containing 1	18643	0.15
chr8_133771865_133772108	0.85	TMEM71	transmembrane protein 71	808	0.63
chr12_15109499_15109902	0.83	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	4500	0.19
chr13_99957828_99957979	0.83	GPR183	G protein-coupled receptor 183	1756	0.38
chr10_6103670_6104125	0.82	IL2RA	interleukin 2 receptor, alpha	356	0.84
chr2_235362717_235362976	0.81	ARL4C	ADP-ribosylation factor-like 4C	42398	0.22
chr7_150148744_150149359	0.75	GIMAP8	GTPase, IMAP family member 8	1333	0.41
chr14_22695818_22695969	0.74	ENSG00000238634	.	85006	0.09
chr16_81031171_81031400	0.73	CMC2	C-x(9)-C motif containing 2	979	0.45
chr7_156761668_156761819	0.69	NOM1	nucleolar protein with MIF4G domain 1	19326	0.16
chr7_150217655_150217806	0.69	GIMAP7	GTPase, IMAP family member 7	5812	0.21
chr13_74807691_74807851	0.69	ENSG00000206617	.	55580	0.16
chr19_2892956_2893107	0.69	ZNF57	zinc finger protein 57	7865	0.11
chr2_196122609_196122760	0.67	ENSG00000202206	.	256076	0.02
chr21_40139305_40139870	0.67	ETS2	v-ets avian erythroblastosis virus E26 oncogene homolog 2	37644	0.21
chr7_50349443_50349694	0.66	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1250	0.61
chr6_139459897_139460408	0.66	HECA	headcase homolog (Drosophila)	3903	0.31
chr1_198609761_198609912	0.66	PTPRC	protein tyrosine phosphatase, receptor type, C	1544	0.48
chr12_67107724_67108271	0.65	GRIP1	glutamate receptor interacting protein 1	35072	0.24
chr17_37933203_37933446	0.65	IKZF3	IKAROS family zinc finger 3 (Aiolos)	1154	0.4
chr7_50345819_50346403	0.64	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1733	0.5
chr2_68963544_68963853	0.64	ARHGAP25	Rho GTPase activating protein 25	1684	0.46
chr20_62270981_62271132	0.63	CTD-3184A7.4		12453	0.09
chr10_127687165_127687316	0.63	FANK1	fibronectin type III and ankyrin repeat domains 1	3254	0.27
chr18_21573835_21574026	0.63	TTC39C	tetratricopeptide repeat domain 39C	1193	0.47
chr1_186292481_186292673	0.63	ENSG00000202025	.	11517	0.17
chr12_4385782_4386106	0.62	CCND2-AS1	CCND2 antisense RNA 1	594	0.46
chr10_111836950_111837776	0.62	ADD3	adducin 3 (gamma)	69641	0.1
chr7_150146102_150146542	0.61	GIMAP8	GTPase, IMAP family member 8	1396	0.39
chr21_35305474_35305968	0.60	LINC00649	long intergenic non-protein coding RNA 649	2203	0.25
chr5_110561342_110561544	0.60	CAMK4	calcium/calmodulin-dependent protein kinase IV	1659	0.44
chr1_239881158_239881438	0.57	ENSG00000233355	.	1068	0.49
chr14_22948566_22948717	0.57	ENSG00000251002	.	1637	0.2
chr7_50415328_50415483	0.57	IKZF1	IKAROS family zinc finger 1 (Ikaros)	48160	0.16
chr17_29637369_29637894	0.57	EVI2B	ecotropic viral integration site 2B	3471	0.16
chr1_198610920_198611071	0.56	PTPRC	protein tyrosine phosphatase, receptor type, C	2703	0.34
chr14_38558504_38558837	0.56	CTD-2058B24.2		1693	0.48
chr5_56125291_56125578	0.56	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	14033	0.16
chr7_142429480_142429631	0.55	PRSS1	protease, serine, 1 (trypsin 1)	27764	0.17
chr6_106970433_106970694	0.55	AIM1	absent in melanoma 1	10833	0.2
chr4_40202894_40203061	0.54	RHOH	ras homolog family member H	1013	0.59
chr17_38018967_38019134	0.54	IKZF3	IKAROS family zinc finger 3 (Aiolos)	1329	0.36
chr3_121373349_121373500	0.53	ENSG00000243544	.	281	0.82
chr1_111417492_111418003	0.52	CD53	CD53 molecule	1971	0.34
chr5_96294037_96294231	0.52	LNPEP	leucyl/cystinyl aminopeptidase	21	0.98
chr2_199271076_199271227	0.51	ENSG00000252511	.	160302	0.04
chr1_101706338_101706489	0.51	RP4-575N6.5		2301	0.23
chr14_88472278_88472651	0.50	GPR65	G protein-coupled receptor 65	996	0.51
chr17_38716835_38717173	0.50	CCR7	chemokine (C-C motif) receptor 7	261	0.91
chr10_65033773_65033924	0.49	JMJD1C	jumonji domain containing 1C	4866	0.31
chr7_50345445_50345596	0.49	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1142	0.64
chr1_169672728_169672969	0.48	SELL	selectin L	7991	0.2
chr12_47611625_47611801	0.48	PCED1B	PC-esterase domain containing 1B	1332	0.49
chr3_151916550_151916780	0.47	MBNL1	muscleblind-like splicing regulator 1	69164	0.11
chr19_3136242_3137376	0.47	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	618	0.58
chr3_151922152_151922513	0.47	MBNL1	muscleblind-like splicing regulator 1	63497	0.12
chr10_8179903_8180054	0.47	GATA3	GATA binding protein 3	83209	0.11
chr1_192546230_192546423	0.46	RGS1	regulator of G-protein signaling 1	1423	0.45
chr2_225809390_225809894	0.46	DOCK10	dedicator of cytokinesis 10	2140	0.45
chr10_62487545_62487752	0.46	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	5600	0.3
chr11_118178183_118178334	0.46	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	2644	0.19
chrX_51545134_51545285	0.46	MAGED1	melanoma antigen family D, 1	894	0.68
chr3_85786117_85786268	0.45	CADM2	cell adhesion molecule 2	10560	0.3
chr11_117873682_117873833	0.45	IL10RA	interleukin 10 receptor, alpha	16648	0.17
chr13_46755525_46755771	0.45	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	811	0.58
chr4_11473602_11473900	0.45	HS3ST1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	42362	0.18
chr6_106968393_106968700	0.45	AIM1	absent in melanoma 1	8816	0.21
chr13_24826594_24826745	0.45	SPATA13	spermatogenesis associated 13	813	0.56
chr14_100532787_100533367	0.44	EVL	Enah/Vasp-like	303	0.88
chr20_51618499_51618650	0.44	TSHZ2	teashirt zinc finger homeobox 2	29628	0.21
chr2_158274562_158274945	0.44	CYTIP	cytohesin 1 interacting protein	21173	0.2
chr1_102637571_102637722	0.44	OLFM3	olfactomedin 3	175060	0.04
chr1_198624965_198625116	0.44	RP11-553K8.5		11150	0.23
chr2_26045186_26045754	0.44	ASXL2	additional sex combs like 2 (Drosophila)	42292	0.17
chr7_38389675_38390189	0.43	AMPH	amphiphysin	112781	0.07
chr11_94960734_94960891	0.43	RP11-712B9.2		2538	0.31
chr5_156616823_156617066	0.43	ITK	IL2-inducible T-cell kinase	9107	0.13
chr4_143488164_143488362	0.43	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	6441	0.35
chr14_22958589_22958740	0.43	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	2493	0.16
chr2_158299271_158299480	0.43	CYTIP	cytohesin 1 interacting protein	1279	0.38
chr5_35859051_35859218	0.42	IL7R	interleukin 7 receptor	2140	0.33
chr5_156610422_156610951	0.42	ITK	IL2-inducible T-cell kinase	2849	0.18
chrX_13680096_13680380	0.42	TCEANC	transcription elongation factor A (SII) N-terminal and central domain containing	6824	0.2
chr6_35271134_35271290	0.42	DEF6	differentially expressed in FDCP 6 homolog (mouse)	5583	0.2
chr2_68961577_68961872	0.42	ARHGAP25	Rho GTPase activating protein 25	189	0.96
chr17_29644174_29644325	0.42	CTD-2370N5.3		1409	0.29
chr1_167483926_167484083	0.42	CD247	CD247 molecule	3771	0.25
chr5_148727072_148727373	0.42	GRPEL2	GrpE-like 2, mitochondrial (E. coli)	2157	0.2
chr2_197033507_197033658	0.42	STK17B	serine/threonine kinase 17b	2142	0.32
chr5_103563842_103563993	0.41	ENSG00000239808	.	32610	0.25
chr10_11213825_11214053	0.41	RP3-323N1.2		600	0.77
chr1_32719471_32719691	0.41	LCK	lymphocyte-specific protein tyrosine kinase	2706	0.13
chr12_19375312_19375463	0.41	PLEKHA5	pleckstrin homology domain containing, family A member 5	14471	0.22
chr2_99346083_99347252	0.40	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	44	0.98
chr2_68978993_68979334	0.40	ARHGAP25	Rho GTPase activating protein 25	17149	0.23
chr6_133084105_133084393	0.40	VNN2	vanin 2	321	0.83
chr14_22771842_22772128	0.40	ENSG00000251002	.	129734	0.04
chr6_26361253_26361404	0.40	BTN3A2	butyrophilin, subfamily 3, member A2	4059	0.11
chr6_32556246_32556444	0.40	HLA-DRB1	major histocompatibility complex, class II, DR beta 1	1280	0.36
chr22_40858929_40859404	0.40	MKL1	megakaryoblastic leukemia (translocation) 1	256	0.92
chr20_39676850_39677439	0.39	TOP1	topoisomerase (DNA) I	19686	0.2
chr5_180243457_180243608	0.39	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	952	0.53
chr15_38854702_38854853	0.39	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	2059	0.32
chr13_49065972_49066123	0.39	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	41166	0.17
chr18_51245241_51245392	0.39	RP11-671P2.1		150663	0.05
chr9_88953252_88953465	0.39	ZCCHC6	zinc finger, CCHC domain containing 6	4680	0.26
chr14_42218476_42218627	0.39	LRFN5	leucine rich repeat and fibronectin type III domain containing 5	49921	0.19
chr1_174935570_174935876	0.39	RABGAP1L	RAB GTPase activating protein 1-like	1818	0.28
chr2_158295494_158296053	0.39	CYTIP	cytohesin 1 interacting protein	153	0.96
chr10_6619930_6620081	0.39	PRKCQ	protein kinase C, theta	2196	0.46
chr21_30204766_30204917	0.39	N6AMT1	N-6 adenine-specific DNA methyltransferase 1 (putative)	52852	0.14
chr17_15586451_15586602	0.39	TRIM16	tripartite motif containing 16	333	0.83
chr7_37381509_37381660	0.39	ELMO1	engulfment and cell motility 1	783	0.68
chr1_198590020_198590171	0.39	PTPRC	protein tyrosine phosphatase, receptor type, C	17706	0.23
chr21_36414032_36414216	0.39	RUNX1	runt-related transcription factor 1	7338	0.33
chr13_41556163_41556400	0.38	ELF1	E74-like factor 1 (ets domain transcription factor)	137	0.96
chr1_200859875_200861145	0.38	C1orf106	chromosome 1 open reading frame 106	41	0.97
chrX_12990488_12990859	0.38	TMSB4X	thymosin beta 4, X-linked	2554	0.33
chr6_90813429_90813580	0.38	ENSG00000222078	.	102279	0.07
chr4_83145308_83145459	0.38	ENSG00000202485	.	49683	0.16
chr6_45982477_45982717	0.38	CLIC5	chloride intracellular channel 5	968	0.6
chr6_109223664_109223815	0.38	ARMC2-AS1	ARMC2 antisense RNA 1	21567	0.2
chr1_229461570_229461782	0.38	RP4-803J11.2		6526	0.15
chr6_144666173_144666513	0.38	UTRN	utrophin	1106	0.59
chr1_9717913_9718080	0.38	C1orf200	chromosome 1 open reading frame 200	3352	0.21
chr14_22887351_22887502	0.38	ENSG00000251002	.	14293	0.12
chr5_56473598_56474064	0.38	GPBP1	GC-rich promoter binding protein 1	2058	0.37
chr1_117301810_117301961	0.37	CD2	CD2 molecule	4796	0.25
chr13_99992298_99992449	0.37	ENSG00000207719	.	16012	0.19
chr8_126960397_126960568	0.37	ENSG00000206695	.	47287	0.2
chr13_41551268_41551419	0.37	ELF1	E74-like factor 1 (ets domain transcription factor)	5075	0.22
chr2_202124822_202124973	0.37	CASP8	caspase 8, apoptosis-related cysteine peptidase	326	0.89
chr16_27415626_27415898	0.37	IL21R	interleukin 21 receptor	1339	0.47
chr10_17705373_17705524	0.37	ENSG00000251959	.	15739	0.14
chr9_128506323_128506474	0.37	PBX3	pre-B-cell leukemia homeobox 3	3226	0.33
chr1_161154335_161154531	0.36	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	7146	0.07
chr2_106413120_106413271	0.36	NCK2	NCK adaptor protein 2	19820	0.25
chr3_53077435_53077586	0.36	SFMBT1	Scm-like with four mbt domains 1	1771	0.34
chr2_41127_41278	0.36	FAM110C	family with sequence similarity 110, member C	5183	0.33
chr15_96422557_96422745	0.36	ENSG00000222076	.	133618	0.06
chr11_94886237_94886421	0.36	RP11-712B9.2		1419	0.51
chr12_9760101_9760256	0.36	KLRB1	killer cell lectin-like receptor subfamily B, member 1	304	0.86
chr10_28909540_28909691	0.36	ENSG00000252401	.	31944	0.16
chr2_7017776_7018587	0.36	RSAD2	radical S-adenosyl methionine domain containing 2	385	0.85
chr1_29253817_29254129	0.36	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	12882	0.18
chr14_22949288_22949494	0.36	ENSG00000251002	.	887	0.35
chr12_59460604_59460755	0.36	RP11-150C16.1		146259	0.04
chr13_99966619_99966770	0.35	GPR183	G protein-coupled receptor 183	7035	0.21
chr7_142423497_142423648	0.35	PRSS1	protease, serine, 1 (trypsin 1)	33747	0.16
chr2_225734023_225734174	0.35	DOCK10	dedicator of cytokinesis 10	52729	0.18
chr1_193506744_193506895	0.35	ENSG00000252241	.	194255	0.03
chr12_32120805_32121101	0.35	KIAA1551	KIAA1551	5530	0.26
chrX_25812581_25812732	0.35	MAGEB18	melanoma antigen family B, 18	343804	0.01
chr5_97126080_97126231	0.35	CTD-2215E18.2		588571	0.0
chr10_73844664_73844815	0.35	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	3347	0.29
chr6_76320868_76321019	0.35	SENP6	SUMO1/sentrin specific peptidase 6	9180	0.17
chr21_19161404_19161758	0.35	AL109761.5		4224	0.27
chr14_94437286_94437966	0.35	ASB2	ankyrin repeat and SOCS box containing 2	2803	0.22
chr20_47436352_47436503	0.35	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	7993	0.28
chr14_22636757_22636908	0.35	ENSG00000238634	.	25945	0.24
chr18_32180370_32180521	0.34	DTNA	dystrobrevin, alpha	7116	0.32
chr3_63937239_63937390	0.34	ATXN7	ataxin 7	16106	0.16
chr5_148726870_148727055	0.34	GRPEL2	GrpE-like 2, mitochondrial (E. coli)	1897	0.22
chr1_169672524_169672675	0.34	SELL	selectin L	8240	0.2
chr1_158903283_158903483	0.34	PYHIN1	pyrin and HIN domain family, member 1	2025	0.36
chr7_115555128_115555279	0.34	TFEC	transcription factor EC	53101	0.16
chr1_111745814_111746254	0.34	DENND2D	DENN/MADD domain containing 2D	997	0.41
chr3_112692076_112692299	0.34	CD200R1	CD200 receptor 1	1572	0.33
chr12_118796178_118796667	0.34	TAOK3	TAO kinase 3	488	0.85
chr8_37755503_37755707	0.34	RAB11FIP1	RAB11 family interacting protein 1 (class I)	1367	0.34
chr14_29078339_29078490	0.34	RP11-966I7.1		156055	0.04
chr3_149419705_149419856	0.34	WWTR1	WW domain containing transcription regulator 1	1280	0.44
chr3_18476194_18476345	0.34	SATB1	SATB homeobox 1	476	0.83
chr3_43331814_43332301	0.34	SNRK	SNF related kinase	3979	0.23
chr14_22972290_22972441	0.34	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	16194	0.09
chr9_134151798_134152108	0.34	FAM78A	family with sequence similarity 78, member A	19	0.98
chr11_314983_315695	0.34	IFITM1	interferon induced transmembrane protein 1	1486	0.17
chr8_67053974_67054125	0.34	TRIM55	tripartite motif containing 55	14771	0.23
chr14_102291094_102291439	0.33	CTD-2017C7.1		14602	0.14
chr12_2410862_2411129	0.33	CACNA1C-IT3	CACNA1C intronic transcript 3 (non-protein coding)	32053	0.21
chr1_206718342_206718493	0.33	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	12076	0.16
chr4_90220151_90220996	0.33	GPRIN3	GPRIN family member 3	8588	0.31
chr1_215313373_215313524	0.33	KCNK2	potassium channel, subfamily K, member 2	56588	0.18
chr4_143488982_143489737	0.32	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	7537	0.34
chr11_46581548_46581763	0.32	AMBRA1	autophagy/beclin-1 regulator 1	31259	0.15
chr12_113344776_113345099	0.32	OAS1	2'-5'-oligoadenylate synthetase 1, 40/46kDa	80	0.97
chr14_32672059_32672251	0.32	ENSG00000202337	.	320	0.8
chr3_195265081_195265237	0.32	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	5017	0.17
chr5_162935820_162936429	0.32	MAT2B	methionine adenosyltransferase II, beta	3504	0.21
chr11_39392973_39393210	0.32	ENSG00000201591	.	110434	0.08
chr6_25040660_25040811	0.32	RP3-425P12.5		1332	0.34
chr21_43825650_43825846	0.32	UBASH3A	ubiquitin associated and SH3 domain containing A	1722	0.26
chr11_116802141_116802415	0.32	SIK3	SIK family kinase 3	25482	0.14
chr14_91877157_91877308	0.32	CCDC88C	coiled-coil domain containing 88C	6458	0.25
chr2_204803308_204803520	0.32	ICOS	inducible T-cell co-stimulator	1911	0.46
chr12_98912505_98912656	0.32	TMPO-AS1	TMPO antisense RNA 1	2380	0.2
chr1_111421280_111421431	0.32	CD53	CD53 molecule	5579	0.21
chr1_114413652_114413958	0.32	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	515	0.69

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BBX

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	0.3	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1	0.7	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.4	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	1.2	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.4	GO:0002517	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.8	GO:0002836	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.5	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.3	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1	0.3	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.2	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.2	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.8	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.3	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.1	0.2	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.6	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.4	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.5	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.3	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.1	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	1.1	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.2	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.5	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.0	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.3	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.2	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.4	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.2	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.9	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.2	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.3	GO:0030260	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.4	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.4	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.4	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:0033622	integrin activation(GO:0033622)
0.0	0.6	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.1	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.3	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.0	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.5	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.3	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	1.2	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.8	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.2	GO:1901186	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.0	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.8	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.0	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.6	GO:0001892	embryonic placenta development(GO:0001892)
0.0	0.3	GO:0051607	defense response to virus(GO:0051607)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.2	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.6	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.2	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:1904590	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0021683	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.0	GO:0014824	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.0	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.2	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.0	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934)
0.0	0.0	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.0	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.0	GO:0035929	steroid hormone secretion(GO:0035929)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.2	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.5	GO:0097194	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.0	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.5	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	0.2	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.3	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.4	GO:0000145	exocyst(GO:0000145)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.7	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.7	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.5	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.0	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	1.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0043218	compact myelin(GO:0043218)
0.0	0.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.4	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.4	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	1.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.3	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.8	GO:0005522	profilin binding(GO:0005522)
0.1	0.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.4	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	1.6	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	1.0	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.2	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.5	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.2	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.2	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.4	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	1.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.2	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.4	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.4	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.0	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.4	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.5	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.0	GO:0004974	leukotriene receptor activity(GO:0004974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	2.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	4.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.7	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.8	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.3	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.6	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.5	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.1	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	2.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	1.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	2.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.0	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.0	REACTOME S PHASE	Genes involved in S Phase
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects