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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for BCL6B

Z-value: 1.58

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Transcription factors associated with BCL6B

Gene Symbol	Gene ID	Gene Info
BCL6B Ensembl NCBI GeneCards UniProt	ENSG00000161940.6	BCL6B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
BCL6B	chr17_6927262_6927413	541	0.501489	-0.65	6.0e-02	Click!
BCL6B	chr17_6926858_6927139	202	0.825004	-0.63	7.0e-02	Click!
BCL6B	chr17_6926552_6926816	112	0.893632	-0.55	1.2e-01	Click!
BCL6B	chr17_6927436_6927587	715	0.383842	-0.38	3.2e-01	Click!
BCL6B	chr17_6932977_6933147	3242	0.089383	-0.33	3.9e-01	Click!

Activity of the BCL6B motif across conditions

Conditions sorted by the z-value of the BCL6B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_55513844_55514378	0.58	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	201	0.95
chr9_117880836_117880987	0.56	TNC	tenascin C	375	0.9
chr2_238321930_238322164	0.55	COL6A3	collagen, type VI, alpha 3	744	0.69
chr5_33891044_33891453	0.54	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	798	0.63
chr6_27721768_27721989	0.43	HIST1H2BL	histone cluster 1, H2bl	53831	0.06
chr19_1591177_1591368	0.42	MBD3	methyl-CpG binding domain protein 3	1380	0.23
chr13_21475841_21475992	0.41	XPO4	exportin 4	997	0.6
chr4_99578892_99579431	0.41	TSPAN5	tetraspanin 5	318	0.81
chr4_81198150_81198317	0.41	FGF5	fibroblast growth factor 5	10440	0.25
chr11_62621592_62621969	0.41	ENSG00000255717	.	23	0.93
chr7_19155354_19155672	0.40	TWIST1	twist family bHLH transcription factor 1	1782	0.28
chr11_14379258_14380093	0.40	RRAS2	related RAS viral (r-ras) oncogene homolog 2	356	0.92
chr6_130088124_130088932	0.40	ENSG00000211996	.	19646	0.24
chr2_1748699_1748904	0.40	PXDN	peroxidasin homolog (Drosophila)	523	0.86
chr11_62320728_62321001	0.39	AHNAK	AHNAK nucleoprotein	2843	0.12
chr1_147013251_147013702	0.39	BCL9	B-cell CLL/lymphoma 9	294	0.94
chr2_217365937_217366088	0.38	RPL37A	ribosomal protein L37a	2149	0.24
chr18_67957874_67958133	0.38	SOCS6	suppressor of cytokine signaling 6	1866	0.41
chr20_2634564_2634928	0.37	ENSG00000221116	.	112	0.85
chr4_8594931_8595082	0.37	CPZ	carboxypeptidase Z	523	0.82
chr22_46478725_46478917	0.36	FLJ27365	hsa-mir-4763	2629	0.15
chr22_39713562_39713713	0.36	RPL3	ribosomal protein L3	982	0.32
chr3_123602332_123603013	0.36	MYLK	myosin light chain kinase	477	0.85
chr12_113859774_113860410	0.35	SDSL	serine dehydratase-like	50	0.97
chr2_216299709_216300678	0.35	FN1	fibronectin 1	597	0.55
chr12_42877884_42878224	0.35	PRICKLE1	prickle homolog 1 (Drosophila)	80	0.97
chr20_43975844_43976401	0.34	SDC4	syndecan 4	942	0.43
chr1_213123311_213123462	0.34	VASH2	vasohibin 2	476	0.85
chr11_844288_844547	0.33	TSPAN4	tetraspanin 4	29	0.92
chr4_143325352_143326244	0.33	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	26614	0.28
chr2_112895388_112895739	0.33	FBLN7	fibulin 7	399	0.89
chr4_86435677_86435949	0.33	ARHGAP24	Rho GTPase activating protein 24	39422	0.22
chr5_136833711_136834156	0.33	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	314	0.93
chr7_129913504_129913799	0.32	CPA2	carboxypeptidase A2 (pancreatic)	6984	0.15
chr11_120208214_120208431	0.32	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	376	0.86
chr1_156675058_156675325	0.32	CRABP2	cellular retinoic acid binding protein 2	202	0.87
chrX_11446077_11446283	0.31	ARHGAP6	Rho GTPase activating protein 6	287	0.95
chr1_227504067_227504291	0.31	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)	704	0.8
chr11_58875134_58875345	0.31	FAM111B	family with sequence similarity 111, member B	529	0.77
chr7_44922298_44922675	0.31	ENSG00000264326	.	1087	0.34
chr6_128839981_128840137	0.31	PTPRK	protein tyrosine phosphatase, receptor type, K	1444	0.38
chrX_2610555_2610727	0.30	CD99	CD99 molecule	1100	0.58
chr4_152021608_152021943	0.30	RPS3A	ribosomal protein S3A	750	0.52
chr10_122216113_122216362	0.30	PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A	229	0.95
chr20_17523751_17523902	0.30	BFSP1	beaded filament structural protein 1, filensin	11812	0.2
chr6_10695950_10696101	0.30	C6orf52	chromosome 6 open reading frame 52	995	0.33
chr11_65324607_65325239	0.30	LTBP3	latent transforming growth factor beta binding protein 3	313	0.76
chr11_27956142_27956384	0.30	RP11-587D21.4		57068	0.15
chrY_2560555_2560707	0.30	ENSG00000251841	.	92159	0.09
chr11_93863372_93863641	0.30	PANX1	pannexin 1	1411	0.53
chr4_99069479_99069630	0.29	STPG2	sperm-tail PG-rich repeat containing 2	5163	0.26
chr3_119896297_119896512	0.29	ENSG00000206721	.	32763	0.16
chr12_7154780_7154931	0.29	C1S	complement component 1, s subcomponent	12964	0.1
chr2_238341641_238342175	0.29	AC112721.1	Uncharacterized protein	7989	0.2
chr3_191048468_191048928	0.29	UTS2B	urotensin 2B	373	0.85
chr3_77089535_77089704	0.29	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	262	0.95
chr3_185960084_185960372	0.29	DGKG	diacylglycerol kinase, gamma 90kDa	38275	0.19
chr1_172109378_172109611	0.29	ENSG00000207949	.	1447	0.39
chr14_34929919_34930181	0.29	SPTSSA	serine palmitoyltransferase, small subunit A	1512	0.47
chr10_24756203_24756381	0.29	KIAA1217	KIAA1217	832	0.69
chr15_75930684_75930835	0.29	IMP3	IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)	1793	0.19
chr1_190447721_190448034	0.28	BRINP3	bone morphogenetic protein/retinoic acid inducible neural-specific 3	1118	0.69
chr4_7878163_7878536	0.28	AFAP1	actin filament associated protein 1	4309	0.28
chr1_74663321_74663472	0.28	LRRIQ3	leucine-rich repeats and IQ motif containing 3	435	0.3
chr16_85269227_85269622	0.28	CTC-786C10.1		64542	0.11
chr11_123065103_123065500	0.28	CLMP	CXADR-like membrane protein	688	0.71
chr5_82768204_82768925	0.28	VCAN	versican	820	0.75
chr12_13349672_13350378	0.28	EMP1	epithelial membrane protein 1	305	0.93
chr8_117883179_117883330	0.28	RAD21	RAD21 homolog (S. pombe)	3345	0.19
chr1_146715427_146715640	0.28	CHD1L	chromodomain helicase DNA binding protein 1-like	1177	0.49
chr19_42581255_42581466	0.28	ZNF574	zinc finger protein 574	1042	0.35
chr7_94279563_94279714	0.28	SGCE	sarcoglycan, epsilon	5772	0.22
chr11_122754419_122754570	0.27	C11orf63	chromosome 11 open reading frame 63	1021	0.55
chr12_110720958_110721647	0.27	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	1816	0.41
chr14_52121858_52122101	0.27	FRMD6	FERM domain containing 6	3281	0.25
chr8_125382455_125382617	0.27	TMEM65	transmembrane protein 65	2397	0.35
chr6_158405199_158405350	0.27	SYNJ2	synaptojanin 2	2204	0.3
chr9_21357722_21357949	0.27	IFNA6	interferon, alpha 6	6458	0.13
chr12_122983015_122983166	0.26	ZCCHC8	zinc finger, CCHC domain containing 8	782	0.59
chr2_203132095_203132497	0.26	NOP58	NOP58 ribonucleoprotein	1857	0.21
chr1_193029578_193029796	0.26	UCHL5	ubiquitin carboxyl-terminal hydrolase L5	450	0.47
chr4_113739998_113740296	0.26	ANK2	ankyrin 2, neuronal	882	0.65
chr11_94513607_94513844	0.26	AMOTL1	angiomotin like 1	12188	0.23
chrX_128655749_128656001	0.26	SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	1585	0.44
chr7_148724335_148724802	0.26	PDIA4	protein disulfide isomerase family A, member 4	992	0.45
chr18_12310772_12310961	0.26	TUBB6	tubulin, beta 6 class V	100	0.97
chr11_93582978_93583471	0.25	VSTM5	V-set and transmembrane domain containing 5	473	0.74
chr17_41984921_41985550	0.25	MPP2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	108	0.94
chr17_66950763_66951090	0.25	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8	456	0.87
chr6_80852871_80853089	0.25	BCKDHB	branched chain keto acid dehydrogenase E1, beta polypeptide	36597	0.23
chr10_112258170_112258629	0.25	DUSP5	dual specificity phosphatase 5	803	0.63
chr13_108518334_108518485	0.25	FAM155A	family with sequence similarity 155, member A	674	0.78
chr17_68133789_68133994	0.25	AC002539.1		8891	0.19
chr17_79069332_79069483	0.25	BAIAP2	BAI1-associated protein 2	1972	0.21
chr6_28366113_28366264	0.25	ZSCAN12	zinc finger and SCAN domain containing 12	1320	0.37
chr16_3449281_3449432	0.24	ZSCAN32	zinc finger and SCAN domain containing 32	1608	0.22
chr10_96121255_96121406	0.24	NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)	381	0.87
chr8_23837042_23837198	0.24	ENSG00000207201	.	97551	0.07
chr4_109967516_109967667	0.24	COL25A1	collagen, type XXV, alpha 1	222216	0.02
chr6_44900994_44901181	0.24	SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	22160	0.28
chrX_34673939_34674563	0.24	TMEM47	transmembrane protein 47	1154	0.68
chr12_86229562_86230264	0.24	RASSF9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	435	0.89
chr12_97379793_97379962	0.24	ENSG00000202368	.	6470	0.31
chr6_28953244_28953516	0.24	HCG15	HLA complex group 15 (non-protein coding)	600	0.54
chr1_11867192_11867412	0.24	MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	325	0.73
chr20_52829309_52829550	0.24	PFDN4	prefoldin subunit 4	5043	0.28
chrX_57148342_57148596	0.24	RP3-323P24.3		374	0.57
chr6_86159887_86160764	0.24	NT5E	5'-nucleotidase, ecto (CD73)	498	0.87
chr8_23837345_23837496	0.24	ENSG00000207201	.	97251	0.08
chr2_12928575_12928807	0.24	ENSG00000264370	.	51198	0.17
chr12_54394768_54394919	0.24	HOXC9	homeobox C9	940	0.22
chr11_133939751_133939941	0.24	JAM3	junctional adhesion molecule 3	880	0.67
chr16_84571908_84572059	0.24	TLDC1	TBC/LysM-associated domain containing 1	15656	0.17
chr1_43637158_43637389	0.24	WDR65	WD repeat domain 65	547	0.48
chr16_86599089_86599240	0.24	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	1693	0.28
chr6_116718983_116719178	0.24	DSE	dermatan sulfate epimerase	26970	0.15
chr4_54967212_54967377	0.24	GSX2	GS homeobox 2	954	0.49
chr1_168329622_168329773	0.24	ENSG00000207974	.	15065	0.23
chr5_14665884_14666035	0.24	FAM105B	family with sequence similarity 105, member B	1102	0.41
chr9_124414074_124414751	0.23	DAB2IP	DAB2 interacting protein	539	0.84
chr3_157156592_157156743	0.23	PTX3	pentraxin 3, long	2089	0.41
chr6_11095182_11095333	0.23	SMIM13	small integral membrane protein 13	991	0.49
chr7_44837548_44837765	0.23	PPIA	peptidylprolyl isomerase A (cyclophilin A)	1376	0.35
chr8_32441306_32441509	0.23	NRG1	neuregulin 1	21759	0.28
chr19_38145180_38145331	0.23	ZFP30	ZFP30 zinc finger protein	375	0.84
chr7_45243750_45244089	0.23	RAMP3	receptor (G protein-coupled) activity modifying protein 3	46491	0.13
chr13_49687457_49688000	0.23	FNDC3A	fibronectin type III domain containing 3A	3279	0.28
chr4_123379678_123379913	0.23	IL2	interleukin 2	1915	0.44
chr1_163038601_163039117	0.23	RGS4	regulator of G-protein signaling 4	76	0.98
chr3_160940495_160941006	0.23	NMD3	NMD3 ribosome export adaptor	1403	0.58
chr19_3671861_3672012	0.23	AC004637.1		644	0.58
chr5_140480603_140480754	0.23	PCDHB3	protocadherin beta 3	444	0.6
chr1_68178990_68179141	0.23	GADD45A	growth arrest and DNA-damage-inducible, alpha	28181	0.18
chr12_94135787_94136106	0.23	RP11-887P2.5		4347	0.27
chr6_153413419_153413831	0.23	RGS17	regulator of G-protein signaling 17	38759	0.14
chr6_112102070_112102221	0.22	FYN	FYN oncogene related to SRC, FGR, YES	138	0.98
chr1_33206819_33207020	0.22	KIAA1522	KIAA1522	567	0.7
chr5_322963_323164	0.22	AHRR	aryl-hydrocarbon receptor repressor	308	0.89
chr4_153303627_153303899	0.22	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	96	0.98
chr5_180685889_180686229	0.22	TRIM52	tripartite motif containing 52	2060	0.13
chr6_35458145_35458450	0.22	TEAD3	TEA domain family member 3	6430	0.17
chr20_30305454_30306019	0.22	AL160175.1		3265	0.17
chr6_100381252_100381443	0.22	MCHR2-AS1	MCHR2 antisense RNA 1	60473	0.14
chr10_33964074_33964254	0.22	NRP1	neuropilin 1	338974	0.01
chr7_44921425_44922084	0.22	ENSG00000264326	.	355	0.79
chr11_114167265_114167463	0.22	NNMT	nicotinamide N-methyltransferase	721	0.72
chr9_21803022_21803324	0.22	MTAP	methylthioadenosine phosphorylase	525	0.78
chr3_71352476_71352627	0.22	FOXP1	forkhead box P1	1360	0.52
chr8_29206404_29207399	0.22	DUSP4	dual specificity phosphatase 4	579	0.71
chr2_65527534_65527956	0.22	SPRED2	sprouty-related, EVH1 domain containing 2	34162	0.18
chr1_182991327_182991478	0.22	LAMC1	laminin, gamma 1 (formerly LAMB2)	1193	0.49
chr12_93964096_93964684	0.22	SOCS2	suppressor of cytokine signaling 2	215	0.85
chr12_131358148_131358299	0.22	RAN	RAN, member RAS oncogene family	1582	0.33
chr2_36585229_36585663	0.22	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	1832	0.5
chr7_15724850_15725001	0.22	MEOX2	mesenchyme homeobox 2	1512	0.49
chr21_17567832_17567983	0.22	ENSG00000201025	.	89182	0.1
chrX_11682905_11683408	0.21	ARHGAP6	Rho GTPase activating protein 6	208	0.97
chr22_38864095_38864404	0.21	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	166	0.93
chrX_99899287_99899446	0.21	SRPX2	sushi-repeat containing protein, X-linked 2	151	0.95
chr10_99407246_99407471	0.21	PI4K2A	phosphatidylinositol 4-kinase type 2 alpha	6915	0.14
chrX_56755732_56756297	0.21	ENSG00000204272	.	322	0.94
chr6_136823903_136824054	0.21	MAP7	microtubule-associated protein 7	23143	0.18
chr9_16267939_16268151	0.21	C9orf92	chromosome 9 open reading frame 92	8266	0.32
chr15_36699845_36700050	0.21	C15orf41	chromosome 15 open reading frame 41	171865	0.04
chr1_144929565_144929716	0.21	PDE4DIP	phosphodiesterase 4D interacting protein	2508	0.23
chr17_17863110_17863392	0.21	TOM1L2	target of myb1-like 2 (chicken)	12460	0.15
chr17_41812174_41812325	0.21	ENSG00000215964	.	13319	0.13
chr20_25229665_25230039	0.21	PYGB	phosphorylase, glycogen; brain	1147	0.46
chr5_138944731_138945044	0.21	UBE2D2	ubiquitin-conjugating enzyme E2D 2	3273	0.22
chr6_56820874_56821079	0.21	BEND6	BEN domain containing 6	806	0.54
chr7_135432429_135432583	0.21	FAM180A	family with sequence similarity 180, member A	954	0.53
chr2_85768416_85768567	0.21	MAT2A	methionine adenosyltransferase II, alpha	1726	0.2
chr15_60060576_60060814	0.21	BNIP2	BCL2/adenovirus E1B 19kDa interacting protein 2	78962	0.08
chr1_92495050_92495201	0.21	EPHX4	epoxide hydrolase 4	414	0.87
chr7_121784101_121784445	0.21	AASS	aminoadipate-semialdehyde synthase	61	0.98
chr2_102930347_102930498	0.21	IL1RL1	interleukin 1 receptor-like 1	2394	0.26
chr5_42423266_42423460	0.21	GHR	growth hormone receptor	516	0.88
chr4_152022521_152022672	0.21	ENSG00000201264	.	613	0.6
chr11_120080847_120081389	0.21	OAF	OAF homolog (Drosophila)	357	0.86
chr10_69645958_69646116	0.21	SIRT1	sirtuin 1	1098	0.54
chrX_70505081_70505341	0.21	NONO	non-POU domain containing, octamer-binding	1167	0.43
chr12_22200754_22200905	0.21	CMAS	cytidine monophosphate N-acetylneuraminic acid synthetase	1721	0.49
chr3_16217443_16217716	0.20	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	1363	0.53
chr4_114899439_114899761	0.20	ARSJ	arylsulfatase family, member J	552	0.84
chr3_156269176_156269606	0.20	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	2523	0.33
chr11_133789632_133789917	0.20	ENSG00000264919	.	21298	0.17
chr18_21974914_21975156	0.20	OSBPL1A	oxysterol binding protein-like 1A	2717	0.21
chr1_86048499_86048650	0.20	CYR61	cysteine-rich, angiogenic inducer, 61	2130	0.3
chr7_86783544_86783895	0.20	DMTF1	cyclin D binding myb-like transcription factor 1	1772	0.31
chr17_33409582_33409733	0.20	RFFL	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	6197	0.11
chr18_73496031_73496230	0.20	SMIM21	small integral membrane protein 21	356472	0.01
chr12_125815735_125816035	0.20	TMEM132B	transmembrane protein 132B	4723	0.36
chr15_96878987_96879612	0.20	ENSG00000222651	.	2809	0.21
chr5_139691412_139691728	0.20	PFDN1	prefoldin subunit 1	8864	0.14
chr16_65151818_65151997	0.20	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	3926	0.39
chr3_131220949_131221185	0.20	MRPL3	mitochondrial ribosomal protein L3	714	0.66
chr1_113499835_113500197	0.20	SLC16A1	solute carrier family 16 (monocarboxylate transporter), member 1	381	0.75
chr2_12861098_12861380	0.20	TRIB2	tribbles pseudokinase 2	2875	0.34
chr7_113996511_113996662	0.20	FOXP2	forkhead box P2	57743	0.15
chr12_64423145_64423296	0.20	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	46915	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BCL6B

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.4	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.4	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.2	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1	0.3	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.1	0.6	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.1	GO:0072143	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.1	0.2	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.2	GO:0000255	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.2	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.2	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.3	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0072239	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0	0.3	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.2	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.0	0.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.3	GO:0015886	heme transport(GO:0015886)
0.0	0.5	GO:0035329	hippo signaling(GO:0035329)
0.0	0.4	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.2	GO:0048535	lymph node development(GO:0048535)
0.0	0.1	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0	0.6	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.6	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.0	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.2	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0001743	optic placode formation(GO:0001743)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.3	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:1901890	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	1.0	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.0	GO:0060391	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.4	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.6	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.2	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:2001234	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.1	GO:0045634	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.2	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0	0.2	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0060039	pericardium development(GO:0060039)
0.0	0.0	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.0	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.3	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.0	GO:0045605	negative regulation of epidermal cell differentiation(GO:0045605)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.4	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.0	0.2	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0019043	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.4	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0070875	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0031645	negative regulation of neurological system process(GO:0031645)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0097480	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.3	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.0	0.0	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.0	GO:0035136	forelimb morphogenesis(GO:0035136)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.0	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0008614	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.0	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.1	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.8	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.1	GO:0010092	specification of organ identity(GO:0010092)
0.0	0.1	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0031297	replication fork processing(GO:0031297)
0.0	0.0	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.2	GO:1902749	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.0	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.0	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0	0.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.2	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.6	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0	0.2	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.0	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.0	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.1	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.3	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.0	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.2	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0043552	regulation of phosphatidylinositol 3-kinase activity(GO:0043551) positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.0	GO:0035082	axoneme assembly(GO:0035082)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.4	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.5	GO:0030673	axolemma(GO:0030673)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.2	GO:0032059	bleb(GO:0032059)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.4	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.3	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	1.1	GO:0005604	basement membrane(GO:0005604)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	3.5	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.4	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.0	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:0005581	collagen trimer(GO:0005581)
0.0	0.5	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	2.1	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.2	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0045545	syndecan binding(GO:0045545)
0.1	0.4	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.5	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.3	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.3	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.5	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.3	GO:0004645	phosphorylase activity(GO:0004645)
0.1	0.3	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	0.2	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.3	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.1	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.4	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.4	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.3	GO:0019841	retinol binding(GO:0019841)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.2	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.3	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.0	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.2	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.0	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.0	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	1.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.0	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.0	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.0	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.4	GO:0001948	glycoprotein binding(GO:0001948)
0.0	0.0	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
1.2	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
1.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.4	PID S1P S1P3 PATHWAY	S1P3 pathway
0.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
2.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	PID S1P S1P2 PATHWAY	S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.5	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling