Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CDX1

Z-value: 1.78

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Transcription factors associated with CDX1

Gene Symbol Gene ID Gene Info
CDX1
ENSG00000113722.12 CDX1

Activity of the CDX1 motif across conditions

Conditions sorted by the z-value of the CDX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_18475449_18475600 0.52 SATB1
 SATB homeobox 1
 1221
 0.51
chr10_14050350_14050950 0.43 FRMD4A
 FERM domain containing 4A
 118
 0.97
chr14_22204676_22204903 0.43 ENSG00000222776
 .
 43996
 0.15
chr20_39769151_39769427 0.42 RP1-1J6.2
2646
 0.27
chr12_47604790_47604941 0.40 PCED1B
 PC-esterase domain containing 1B
 5187
 0.24
chr6_5498765_5499077 0.40 RP1-232P20.1
40613
 0.2
chr2_102374666_102374817 0.39 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 38985
 0.21
chr5_55288940_55289137 0.39 IL6ST
 interleukin 6 signal transducer (gp130, oncostatin M receptor)
 1754
 0.26
chr7_98739090_98739248 0.38 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
 2473
 0.34
chr11_78884847_78885153 0.37 TENM4
 teneurin transmembrane protein 4
 41954
 0.21
chr12_92532493_92532715 0.37 C12orf79
 chromosome 12 open reading frame 79
 1807
 0.32
chr1_39658092_39658302 0.37 MACF1
 microtubule-actin crosslinking factor 1
 11721
 0.17
chr8_10367956_10368344 0.37 PRSS51
 protease, serine, 51
 7375
 0.19
chr3_88667439_88667590 0.36 ENSG00000207316
 .
 187173
 0.03
chr12_57458010_57458211 0.36 MYO1A
 myosin IA
 13151
 0.09
chr20_7675894_7676045 0.36 ENSG00000221726
 .
 1655
 0.51
chr10_31036935_31037086 0.35 SVILP1
 supervillin pseudogene 1
 52160
 0.15
chr16_24554033_24554401 0.35 RBBP6
 retinoblastoma binding protein 6
 2313
 0.41
chr16_1585013_1585440 0.35 TMEM204
 transmembrane protein 204
 1652
 0.19
chr10_62491122_62491273 0.35 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 2051
 0.43
chr5_53959381_53959532 0.34 SNX18
 sorting nexin 18
 145863
 0.04
chr1_111215065_111215351 0.34 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 2447
 0.28
chr2_120687963_120688114 0.34 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 686
 0.74
chr3_110789324_110789580 0.34 PVRL3
 poliovirus receptor-related 3
 490
 0.57
chr12_91575790_91576058 0.34 DCN
 decorin
 505
 0.87
chr12_50614114_50614771 0.33 RP3-405J10.4
1055
 0.35
chr9_99214684_99214835 0.33 HABP4
 hyaluronan binding protein 4
 2272
 0.34
chr10_24738869_24739102 0.32 KIAA1217
 KIAA1217
 623
 0.8
chr10_28384553_28384835 0.32 ARMC4
 armadillo repeat containing 4
 96717
 0.08
chr6_44900327_44900782 0.32 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 22693
 0.28
chr9_3824695_3824846 0.32 RP11-252M18.3
50814
 0.17
chr3_60062649_60062918 0.31 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 105200
 0.08
chr15_100247411_100247781 0.31 DKFZP779J2370
10433
 0.15
chr13_42401725_42401979 0.31 ENSG00000241406
 .
 20039
 0.24
chr17_29485980_29486219 0.31 RP11-142O6.1
25899
 0.14
chr13_33627122_33627355 0.31 ENSG00000221677
 .
 11749
 0.24
chr10_23001160_23001461 0.31 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
 1727
 0.49
chr2_229045479_229045630 0.31 SPHKAP
 SPHK1 interactor, AKAP domain containing
 788
 0.72
chr13_80824234_80824440 0.30 SPRY2
 sprouty homolog 2 (Drosophila)
 89457
 0.1
chr3_105585580_105586174 0.30 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 2010
 0.51
chr1_57039327_57039478 0.30 PPAP2B
 phosphatidic acid phosphatase type 2B
 5839
 0.3
chr8_107738372_107738544 0.30 OXR1
 oxidation resistance 1
 45
 0.98
chr4_48135850_48136064 0.30 TXK
 TXK tyrosine kinase
 316
 0.88
chr5_23013128_23013556 0.30 CDH12
 cadherin 12, type 2 (N-cadherin 2)
 159611
 0.04
chr14_99725147_99725681 0.29 AL109767.1
3871
 0.26
chr18_19927744_19927895 0.29 CTAGE1
 cutaneous T-cell lymphoma-associated antigen 1
 67011
 0.11
chr16_57048273_57048580 0.29 NLRC5
 NLR family, CARD domain containing 5
 6199
 0.15
chrX_12971375_12971526 0.28 TMSB4X
 thymosin beta 4, X-linked
 21777
 0.18
chr2_220407254_220407405 0.28 CHPF
 chondroitin polymerizing factor
 490
 0.51
chr14_99681730_99682557 0.28 AL109767.1
47142
 0.14
chr12_96592115_96592322 0.28 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
 3826
 0.25
chr12_47607778_47608233 0.28 PCED1B
 PC-esterase domain containing 1B
 2047
 0.36
chr2_162929081_162929475 0.28 AC008063.2
488
 0.77
chr13_97876069_97876689 0.28 MBNL2
 muscleblind-like splicing regulator 2
 1770
 0.5
chr3_150919418_150919700 0.28 GPR171
 G protein-coupled receptor 171
 1420
 0.35
chr3_87035332_87035763 0.28 VGLL3
 vestigial like 3 (Drosophila)
 4305
 0.37
chr11_35156719_35156870 0.27 RP4-607I7.1
2479
 0.24
chr11_96040354_96040983 0.27 ENSG00000266192
 .
 33934
 0.17
chr10_531510_531790 0.27 RP11-490E15.2
48149
 0.14
chr17_46654927_46655231 0.27 HOXB3
 homeobox B3
 1640
 0.15
chr6_106548437_106548588 0.27 RP1-134E15.3
497
 0.78
chr7_94003845_94004266 0.27 COL1A2
 collagen, type I, alpha 2
 19818
 0.26
chrY_15587172_15587323 0.27 UTY
 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
 4298
 0.35
chr18_67623543_67623764 0.27 CD226
 CD226 molecule
 253
 0.95
chr2_162565857_162566070 0.27 SLC4A10
 solute carrier family 4, sodium bicarbonate transporter, member 10
 84992
 0.1
chrX_2767181_2767441 0.27 GYG2-AS1
 GYG2 antisense RNA 1
 4490
 0.18
chr7_15722890_15723041 0.27 MEOX2
 mesenchyme homeobox 2
 3472
 0.3
chr13_36047635_36048256 0.27 MAB21L1
 mab-21-like 1 (C. elegans)
 2887
 0.26
chr11_9599012_9599618 0.26 WEE1
 WEE1 G2 checkpoint kinase
 17
 0.78
chr21_25801813_25801964 0.26 ENSG00000232512
 .
 671557
 0.0
chr5_52336982_52337335 0.26 CTD-2366F13.2
48140
 0.12
chr9_106390857_106391008 0.26 ENSG00000253031
 .
 60927
 0.17
chr2_69867626_69867777 0.26 AAK1
 AP2 associated kinase 1
 3085
 0.28
chr1_222578153_222578517 0.26 ENSG00000222399
 .
 98742
 0.08
chr10_52176688_52176970 0.26 AC069547.2
 Uncharacterized protein
 24063
 0.19
chr6_155739085_155739637 0.26 NOX3
 NADPH oxidase 3
 37676
 0.2
chr17_33860193_33860344 0.26 SLFN12L
 schlafen family member 12-like
 4612
 0.13
chr17_58979551_58979702 0.26 ENSG00000264322
 .
 2374
 0.3
chr20_3779038_3779189 0.26 CDC25B
 cell division cycle 25B
 2035
 0.21
chr13_100392347_100392498 0.26 CLYBL-AS1
 CLYBL antisense RNA 1
 12677
 0.18
chr5_110560650_110560918 0.26 CAMK4
 calcium/calmodulin-dependent protein kinase IV
 1000
 0.62
chr15_29131798_29132394 0.26 APBA2
 amyloid beta (A4) precursor protein-binding, family A, member 2
 787
 0.68
chr2_120687485_120687636 0.26 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 208
 0.95
chr3_108543496_108543820 0.25 TRAT1
 T cell receptor associated transmembrane adaptor 1
 2039
 0.42
chr5_54829535_54829686 0.25 PPAP2A
 phosphatidic acid phosphatase type 2A
 1187
 0.54
chr8_94931050_94931201 0.25 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
 13
 0.98
chr4_153431926_153432077 0.25 ENSG00000264678
 .
 21433
 0.17
chr12_95557800_95557974 0.25 FGD6
 FYVE, RhoGEF and PH domain containing 6
 47138
 0.13
chr6_167526422_167526606 0.25 CCR6
 chemokine (C-C motif) receptor 6
 1219
 0.48
chr2_208397856_208398007 0.25 CREB1
 cAMP responsive element binding protein 1
 3103
 0.25
chr1_67926705_67926856 0.25 SERBP1
 SERPINE1 mRNA binding protein 1
 30682
 0.17
chr12_9822383_9822619 0.25 CLEC2D
 C-type lectin domain family 2, member D
 152
 0.93
chr15_35959426_35959743 0.25 DPH6
 diphthamine biosynthesis 6
 121191
 0.07
chr2_204570249_204570400 0.25 CD28
 CD28 molecule
 874
 0.69
chr3_189766902_189767149 0.25 ENSG00000265045
 .
 64698
 0.1
chr2_231822566_231822748 0.25 GPR55
 G protein-coupled receptor 55
 3124
 0.23
chr3_145670165_145670316 0.25 RP11-274H2.5
109226
 0.06
chr11_128384304_128384833 0.25 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 7528
 0.24
chr4_162498417_162498568 0.25 RP11-234O6.2
198387
 0.03
chr8_22299319_22300279 0.25 PPP3CC
 protein phosphatase 3, catalytic subunit, gamma isozyme
 921
 0.52
chr7_138777992_138778143 0.25 ZC3HAV1
 zinc finger CCCH-type, antiviral 1
 14054
 0.2
chr13_67803587_67803738 0.24 PCDH9
 protocadherin 9
 801
 0.79
chr4_26301131_26301282 0.24 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 20078
 0.28
chr8_120649956_120650241 0.24 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
 922
 0.68
chr20_9074244_9074481 0.24 PLCB4
 phospholipase C, beta 4
 24614
 0.22
chr2_231785296_231785447 0.24 GPR55
 G protein-coupled receptor 55
 4570
 0.18
chr2_234934408_234934643 0.24 SPP2
 secreted phosphoprotein 2, 24kDa
 24798
 0.2
chr6_154567391_154567649 0.24 IPCEF1
 interaction protein for cytohesin exchange factors 1
 470
 0.9
chr9_73026328_73026548 0.24 KLF9
 Kruppel-like factor 9
 3102
 0.35
chr1_19933664_19933939 0.24 MINOS1-NBL1
 MINOS1-NBL1 readthrough
 10240
 0.13
chr14_22979723_22979978 0.24 TRAJ15
 T cell receptor alpha joining 15
 18730
 0.09
chr2_42094920_42095168 0.24 ENSG00000223245
 .
 3367
 0.27
chr1_150082798_150082965 0.24 PLEKHO1
 pleckstrin homology domain containing, family O member 1
 38492
 0.11
chr1_215313373_215313524 0.24 KCNK2
 potassium channel, subfamily K, member 2
 56588
 0.18
chr7_30360496_30360732 0.24 ENSG00000207771
 .
 31204
 0.17
chr4_135119262_135119413 0.24 PABPC4L
 poly(A) binding protein, cytoplasmic 4-like
 3566
 0.39
chr10_131770273_131770744 0.24 EBF3
 early B-cell factor 3
 8403
 0.31
chr11_85429273_85429899 0.24 SYTL2
 synaptotagmin-like 2
 55
 0.97
chr16_87523844_87524419 0.24 ZCCHC14
 zinc finger, CCHC domain containing 14
 1520
 0.43
chr6_5538401_5538552 0.24 RP1-232P20.1
80168
 0.11
chr7_15722543_15722766 0.24 MEOX2
 mesenchyme homeobox 2
 3783
 0.3
chr5_58422483_58422634 0.24 RP11-266N13.2
86970
 0.1
chr12_59265576_59265746 0.24 LRIG3
 leucine-rich repeats and immunoglobulin-like domains 3
 2693
 0.36
chr16_84802144_84802295 0.24 USP10
 ubiquitin specific peptidase 10
 346
 0.89
chr3_189073765_189073916 0.24 TPRG1-AS2
 TPRG1 antisense RNA 2
 115457
 0.07
chrX_78202204_78202379 0.24 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
 1373
 0.61
chr2_145787262_145787615 0.23 ENSG00000253036
 .
 305200
 0.01
chr9_19129523_19129674 0.23 PLIN2
 perilipin 2
 2024
 0.25
chr2_225903553_225903704 0.23 DOCK10
 dedicator of cytokinesis 10
 3531
 0.33
chr9_44867829_44868127 0.23 RP11-160N1.10
407
 0.89
chr4_93374649_93374800 0.23 GRID2
 glutamate receptor, ionotropic, delta 2
 148916
 0.05
chr2_106354976_106355256 0.23 NCK2
 NCK adaptor protein 2
 6238
 0.32
chr5_35861996_35862147 0.23 IL7R
 interleukin 7 receptor
 5077
 0.23
chr13_99959249_99959863 0.23 GPR183
 G protein-coupled receptor 183
 103
 0.97
chr2_235402543_235402910 0.23 ARL4C
 ADP-ribosylation factor-like 4C
 2518
 0.45
chr13_98021150_98021576 0.23 ENSG00000202290
 .
 6008
 0.24
chr6_112192884_112193487 0.23 FYN
 FYN oncogene related to SRC, FGR, YES
 1055
 0.66
chr4_138450820_138450981 0.23 PCDH18
 protocadherin 18
 2665
 0.44
chr12_14540053_14540282 0.22 ATF7IP
 activating transcription factor 7 interacting protein
 2169
 0.39
chr2_235401897_235402222 0.22 ARL4C
 ADP-ribosylation factor-like 4C
 3185
 0.41
chr14_99710738_99710933 0.22 AL109767.1
18450
 0.2
chr21_27450265_27450416 0.22 APP
 amyloid beta (A4) precursor protein
 12037
 0.25
chr9_2158782_2159230 0.22 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 493
 0.82
chr18_4119851_4120002 0.22 DLGAP1
 discs, large (Drosophila) homolog-associated protein 1
 31364
 0.23
chr5_79514748_79514899 0.22 ENSG00000239159
 .
 20585
 0.18
chr10_6618861_6619012 0.22 PRKCQ
 protein kinase C, theta
 3265
 0.39
chr11_121800761_121801203 0.22 ENSG00000252556
 .
 74081
 0.11
chr16_47813458_47814031 0.22 PHKB
 phosphorylase kinase, beta
 83361
 0.1
chr13_47190445_47190629 0.22 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
 63142
 0.14
chr6_152505938_152506206 0.22 SYNE1
 spectrin repeat containing, nuclear envelope 1
 16573
 0.28
chr12_22483664_22483815 0.22 ST8SIA1
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
 3358
 0.37
chr11_96073941_96074227 0.22 ENSG00000266192
 .
 518
 0.76
chr1_117301810_117301961 0.22 CD2
 CD2 molecule
 4796
 0.25
chr5_40442254_40442405 0.22 ENSG00000265615
 .
 121909
 0.06
chr1_198492691_198493057 0.22 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 16930
 0.28
chr8_13363407_13363558 0.21 DLC1
 deleted in liver cancer 1
 6732
 0.24
chr2_165654913_165655064 0.21 COBLL1
 cordon-bleu WH2 repeat protein-like 1
 24724
 0.18
chr21_26945391_26945673 0.21 ENSG00000234883
 .
 760
 0.65
chr15_37389081_37389380 0.21 MEIS2
 Meis homeobox 2
 338
 0.88
chr9_131318956_131319107 0.21 SPTAN1
 spectrin, alpha, non-erythrocytic 1
 4162
 0.14
chr10_63697159_63697310 0.21 ENSG00000221272
 .
 10457
 0.26
chr13_99958832_99958994 0.21 GPR183
 G protein-coupled receptor 183
 746
 0.69
chr6_109837269_109837497 0.21 AK9
 adenylate kinase 9
 9762
 0.14
chr5_51565570_51565721 0.21 CTD-2203A3.1
 Uncharacterized protein
 259996
 0.02
chr11_18368890_18369041 0.21 GTF2H1
 general transcription factor IIH, polypeptide 1, 62kDa
 314
 0.84
chr2_164675473_164675624 0.21 FIGN
 fidgetin
 83026
 0.12
chr6_130453758_130453909 0.21 RP11-73O6.3
5508
 0.26
chr11_104787850_104788088 0.21 RP11-693N9.2
7327
 0.2
chr22_34001610_34001761 0.21 LARGE
 like-glycosyltransferase
 33446
 0.21
chr10_15126072_15126273 0.21 ACBD7
 acyl-CoA binding domain containing 7
 4603
 0.18
chr6_766934_767097 0.21 EXOC2
 exocyst complex component 2
 73898
 0.12
chr5_23013590_23013917 0.21 CDH12
 cadherin 12, type 2 (N-cadherin 2)
 160022
 0.04
chr6_56707059_56707245 0.21 DST
 dystonin
 791
 0.6
chr16_87414863_87415370 0.21 FBXO31
 F-box protein 31
 2247
 0.19
chr7_150205207_150205392 0.21 GIMAP7
 GTPase, IMAP family member 7
 6619
 0.2
chr2_120518344_120518699 0.21 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 721
 0.76
chr4_113773501_113773652 0.21 RP11-119H12.6
29910
 0.17
chr20_30948041_30948438 0.21 ASXL1
 additional sex combs like 1 (Drosophila)
 689
 0.71
chr18_72355901_72356083 0.21 ZNF407
 zinc finger protein 407
 13016
 0.28
chr10_63813971_63814567 0.21 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 5299
 0.3
chr2_189842795_189842946 0.21 ENSG00000221502
 .
 52
 0.98
chr11_94801551_94801758 0.21 ENDOD1
 endonuclease domain containing 1
 21320
 0.19
chr2_197159119_197159270 0.21 ENSG00000264627
 .
 5061
 0.24
chr4_170189368_170189538 0.20 SH3RF1
 SH3 domain containing ring finger 1
 1655
 0.5
chr1_236222165_236222316 0.20 ENSG00000252822
 .
 1737
 0.38
chrX_86773791_86773975 0.20 KLHL4
 kelch-like family member 4
 1066
 0.64
chr14_50363534_50363977 0.20 ARF6
 ADP-ribosylation factor 6
 3945
 0.15
chr18_55863175_55863444 0.20 RP11-718I15.1
381
 0.52
chr4_114897314_114897610 0.20 ARSJ
 arylsulfatase family, member J
 2690
 0.37
chr12_20527112_20527263 0.20 RP11-284H19.1
3991
 0.28
chr15_57199778_57200042 0.20 ZNF280D
 zinc finger protein 280D
 10859
 0.22
chr12_41126076_41126227 0.20 CNTN1
 contactin 1
 10002
 0.31
chr2_204398750_204399136 0.20 RAPH1
 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
 787
 0.76
chr1_160766044_160766224 0.20 LY9
 lymphocyte antigen 9
 157
 0.95
chr3_105895313_105895556 0.20 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 307038
 0.01
chr2_102091330_102091588 0.20 RFX8
 RFX family member 8, lacking RFX DNA binding domain
 294
 0.94
chr5_139489002_139489153 0.20 LINC01024
 long intergenic non-protein coding RNA 1024
 862
 0.52
chr2_199237110_199237329 0.20 ENSG00000252511
 .
 194234
 0.03
chr2_26017208_26017426 0.20 ASXL2
 additional sex combs like 2 (Drosophila)
 14139
 0.24
chr6_26442034_26442281 0.20 BTN3A3
 butyrophilin, subfamily 3, member A3
 1371
 0.29

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of CDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.2 0.7 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.3 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.4 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.4 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1 0.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.5 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.8 GO:0002839 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1 0.3 GO:0002913 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 0.7 GO:0043383 negative T cell selection(GO:0043383)
0.1 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.3 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.4 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.2 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.2 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.5 GO:0048535 lymph node development(GO:0048535)
0.1 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.2 GO:0031579 membrane raft organization(GO:0031579)
0.1 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.2 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1 0.2 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 0.1 GO:0050955 thermoception(GO:0050955)
0.1 0.2 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.2 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.5 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.3 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0060044 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.2 GO:0042634 regulation of hair cycle(GO:0042634)
0.0 0.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.4 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:1902749 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.0 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0060841 venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0010955 negative regulation of plasminogen activation(GO:0010757) negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.0 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0002363 alpha-beta T cell lineage commitment(GO:0002363)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0021532 neural tube patterning(GO:0021532)
0.0 0.6 GO:0006997 nucleus organization(GO:0006997)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.1 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.2 GO:0007350 blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0090103 cochlea morphogenesis(GO:0090103)
0.0 0.1 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.0 GO:0051938 L-glutamate import(GO:0051938)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0007440 foregut morphogenesis(GO:0007440)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0031529 ruffle organization(GO:0031529)
0.0 0.0 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.0 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 0.1 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0071875 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.9 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.2 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0033083 regulation of immature T cell proliferation(GO:0033083)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.2 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.0 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.2 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.0 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.0 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.0 GO:0090312 regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.0 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.0 GO:0014002 astrocyte development(GO:0014002)
0.0 0.0 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.0 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0044409 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:0032823 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.0 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.0 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.0 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0010171 body morphogenesis(GO:0010171)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:1901976 regulation of spindle checkpoint(GO:0090231) regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.0 GO:0014824 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.4 GO:0002102 podosome(GO:0002102)
0.1 0.3 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.5 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.0 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.0 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.0 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.0 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0005113 patched binding(GO:0005113)
0.1 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0034711 inhibin binding(GO:0034711)
0.1 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.2 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.0 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016715 dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.3 GO:0005035 death receptor activity(GO:0005035)
0.0 0.6 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.1 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.2 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.0 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.1 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 1.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
0.0 0.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.0 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.0 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells