Project

ENCODE: H3K4me3 ChIP-Seq of primary human cells

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CDX2

Z-value: 1.16

Motif logo

Transcription factors associated with CDX2

Gene Symbol	Gene ID	Gene Info
CDX2 Ensembl NCBI GeneCards UniProt	ENSG00000165556.9	CDX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
CDX2	chr13_28542515_28542921	2558	0.211068	-0.44	2.3e-01	Click!
CDX2	chr13_28552170_28552321	6969	0.146887	-0.19	6.2e-01	Click!
CDX2	chr13_28534474_28535073	10503	0.135990	-0.08	8.5e-01	Click!
CDX2	chr13_28535463_28535614	9738	0.137578	-0.05	9.1e-01	Click!
CDX2	chr13_28534258_28534409	10943	0.135126	0.03	9.3e-01	Click!

Activity of the CDX2 motif across conditions

Conditions sorted by the z-value of the CDX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_134464463_134465343	1.11	CALD1	caldesmon 1	474	0.89
chr3_87036535_87037613	0.75	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chr11_63639674_63640171	0.69	MARK2	MAP/microtubule affinity-regulating kinase 2	3174	0.18
chr11_132813237_132813595	0.66	OPCML	opioid binding protein/cell adhesion molecule-like	150	0.98
chr8_37350646_37351319	0.65	RP11-150O12.6		23557	0.24
chr5_14036568_14037099	0.64	DNAH5	dynein, axonemal, heavy chain 5	92181	0.09
chr5_120114458_120114855	0.63	ENSG00000222609	.	68121	0.14
chr15_96883311_96883827	0.63	ENSG00000222651	.	7079	0.16
chr4_159731146_159731380	0.62	FNIP2	folliculin interacting protein 2	3863	0.25
chr4_87516254_87516849	0.62	PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	295	0.87
chr6_53928552_53928746	0.61	MLIP-AS1	MLIP antisense RNA 1	15875	0.2
chr10_74854370_74854615	0.59	P4HA1	prolyl 4-hydroxylase, alpha polypeptide I	2116	0.19
chr10_33620428_33620906	0.57	NRP1	neuropilin 1	2643	0.37
chr18_9615856_9616007	0.53	PPP4R1	protein phosphatase 4, regulatory subunit 1	693	0.62
chr12_7651228_7651481	0.52	CD163	CD163 molecule	3979	0.25
chr7_132299406_132299928	0.52	PLXNA4	plexin A4	33780	0.18
chr19_4061458_4061934	0.52	CTD-2622I13.3		1051	0.37
chr3_112358713_112358917	0.52	CCDC80	coiled-coil domain containing 80	1301	0.54
chr1_221067632_221067991	0.52	HLX	H2.0-like homeobox	13227	0.2
chr9_21964953_21966022	0.51	C9orf53	chromosome 9 open reading frame 53	1650	0.31
chr15_39871853_39872515	0.51	THBS1	thrombospondin 1	1096	0.52
chr7_116164164_116164509	0.50	CAV1	caveolin 1, caveolae protein, 22kDa	503	0.76
chr7_5467738_5468320	0.49	TNRC18	trinucleotide repeat containing 18	2984	0.19
chr21_36167680_36167831	0.48	AP000330.8		49621	0.16
chr17_69773494_69773789	0.48	AC007461.1	Uncharacterized protein	262523	0.02
chr13_36045367_36045518	0.48	MAB21L1	mab-21-like 1 (C. elegans)	5390	0.22
chr1_231963429_231963641	0.48	DISC1-IT1	DISC1 intronic transcript 1 (non-protein coding)	98045	0.08
chr12_1465959_1466110	0.47	RP5-951N9.2		28965	0.18
chr10_4285370_4285529	0.46	ENSG00000207124	.	271695	0.02
chr15_99788624_99789059	0.46	TTC23	tetratricopeptide repeat domain 23	895	0.51
chr5_92921648_92921875	0.45	ENSG00000237187	.	407	0.85
chr10_114714851_114715858	0.44	RP11-57H14.2		3720	0.26
chr2_45823201_45823510	0.44	SRBD1	S1 RNA binding domain 1	15065	0.21
chr5_158611818_158612659	0.44	RNF145	ring finger protein 145	22404	0.16
chr4_89977525_89978081	0.44	FAM13A	family with sequence similarity 13, member A	508	0.85
chr1_224022481_224022658	0.43	TP53BP2	tumor protein p53 binding protein, 2	11063	0.26
chr15_48960228_48960461	0.43	FBN1	fibrillin 1	22298	0.23
chr10_69916813_69916964	0.42	ENSG00000222371	.	948	0.6
chr17_45959589_45959832	0.42	SP2	Sp2 transcription factor	13806	0.1
chr13_76213824_76214088	0.42	LMO7	LIM domain 7	3497	0.21
chr4_86700210_86700446	0.42	ARHGAP24	Rho GTPase activating protein 24	469	0.88
chr19_41932700_41933275	0.42	B3GNT8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	1648	0.18
chr12_26379464_26379833	0.41	SSPN	sarcospan	31042	0.17
chr3_29327656_29328192	0.41	RBMS3-AS3	RBMS3 antisense RNA 3	4293	0.26
chr11_101918556_101918783	0.41	C11orf70	chromosome 11 open reading frame 70	480	0.77
chr3_128207705_128209147	0.41	RP11-475N22.4		326	0.79
chr1_65363518_65363760	0.41	JAK1	Janus kinase 1	68548	0.12
chr13_73664940_73665091	0.41	ENSG00000200267	.	22140	0.18
chr8_65754459_65754681	0.41	CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	43252	0.2
chr15_99789888_99790153	0.40	TTC23	tetratricopeptide repeat domain 23	205	0.9
chr15_65805259_65805472	0.40	DPP8	dipeptidyl-peptidase 8	196	0.92
chr4_114899439_114899761	0.40	ARSJ	arylsulfatase family, member J	552	0.84
chr10_29923748_29924013	0.40	SVIL	supervillin	21	0.98
chr4_157700078_157700308	0.40	RP11-154F14.2		62318	0.13
chr10_117577472_117577686	0.40	GFRA1	GDNF family receptor alpha 1	437728	0.01
chr8_58715313_58715521	0.40	FAM110B	family with sequence similarity 110, member B	191696	0.03
chr7_123284039_123284287	0.40	LMOD2	leiomodin 2 (cardiac)	11698	0.17
chr2_197852125_197852688	0.39	ANKRD44	ankyrin repeat domain 44	12820	0.25
chr6_105388737_105389249	0.39	LIN28B	lin-28 homolog B (C. elegans)	15930	0.23
chr21_17489963_17490188	0.39	ENSG00000252273	.	82246	0.11
chr7_94029074_94029225	0.39	COL1A2	collagen, type I, alpha 2	5276	0.3
chr7_114207737_114207888	0.39	ENSG00000202334	.	46149	0.15
chr7_113722711_113723554	0.39	FOXP2	forkhead box P2	3483	0.3
chr18_21264816_21264967	0.38	LAMA3	laminin, alpha 3	4516	0.24
chr14_23623374_23623574	0.38	SLC7A8	solute carrier family 7 (amino acid transporter light chain, L system), member 8	128	0.92
chr12_54427392_54427581	0.38	ENSG00000207571	.	248	0.73
chr19_45995836_45996758	0.38	RTN2	reticulon 2	228	0.87
chr7_41740779_41741576	0.38	INHBA	inhibin, beta A	970	0.56
chr7_38670068_38671048	0.38	AMPH	amphiphysin	462	0.87
chr15_86164203_86164426	0.38	RP11-815J21.3		6606	0.15
chr15_38547811_38548278	0.37	SPRED1	sprouty-related, EVH1 domain containing 1	2662	0.42
chr5_72733592_72733937	0.37	FOXD1	forkhead box D1	10588	0.21
chr9_12859535_12860149	0.37	ENSG00000222658	.	25478	0.2
chr2_55239455_55239731	0.37	RTN4	reticulon 4	2008	0.3
chr2_238596792_238597019	0.37	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	3883	0.27
chr12_101188560_101188771	0.37	ANO4	anoctamin 4	70	0.98
chr9_20558698_20558876	0.37	ENSG00000252324	.	17429	0.2
chr5_88238184_88238467	0.37	MEF2C-AS1	MEF2C antisense RNA 1	579	0.83
chr5_98112819_98113202	0.37	RGMB	repulsive guidance molecule family member b	3671	0.26
chr15_48436377_48436744	0.37	MYEF2	myelin expression factor 2	4963	0.17
chr5_145319076_145319227	0.37	SH3RF2	SH3 domain containing ring finger 2	1711	0.46
chr1_86846919_86847201	0.37	ODF2L	outer dense fiber of sperm tails 2-like	1819	0.42
chr4_184509430_184509787	0.37	ENSG00000239116	.	6154	0.2
chr11_11605687_11605838	0.37	RP11-483L5.1		14131	0.22
chrX_13906420_13906604	0.37	GPM6B	glycoprotein M6B	664	0.81
chr4_85420275_85420452	0.36	NKX6-1	NK6 homeobox 1	760	0.77
chr3_71158276_71158520	0.36	FOXP1	forkhead box P1	21346	0.28
chr1_243962680_243962831	0.36	AKT3-IT1	AKT3 intronic transcript 1 (non-protein coding)	5053	0.27
chr6_114182367_114182913	0.36	MARCKS	myristoylated alanine-rich protein kinase C substrate	4099	0.23
chr13_65686743_65686894	0.36	ENSG00000221685	.	751487	0.0
chr13_21654404_21654812	0.36	LATS2	large tumor suppressor kinase 2	18922	0.14
chr10_117577799_117577950	0.36	GFRA1	GDNF family receptor alpha 1	437433	0.01
chr13_80912572_80913077	0.36	SPRY2	sprouty homolog 2 (Drosophila)	970	0.67
chr4_27219934_27220157	0.36	ENSG00000222206	.	5004	0.36
chr18_25757173_25757741	0.36	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	47	0.99
chr5_124748629_124749002	0.36	ENSG00000222107	.	61991	0.16
chr3_30730881_30731077	0.36	RP11-1024P17.1		8174	0.3
chr5_88174722_88174873	0.36	MEF2C	myocyte enhancer factor 2C	1003	0.61
chr10_112295759_112296296	0.36	SMC3	structural maintenance of chromosomes 3	31422	0.13
chr12_117036919_117037510	0.36	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2	23558	0.24
chr18_74189277_74189488	0.36	ZNF516	zinc finger protein 516	13353	0.17
chr5_111090218_111090459	0.36	NREP	neuronal regeneration related protein	1610	0.42
chr12_1428214_1428403	0.36	RP5-951N9.2		66691	0.11
chr11_5642308_5642558	0.35	TRIM34	tripartite motif containing 34	1439	0.24
chr7_116441355_116441506	0.35	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	9694	0.21
chr17_74706029_74706760	0.35	MXRA7	matrix-remodelling associated 7	643	0.49
chr6_148845639_148845819	0.35	ENSG00000223322	.	353	0.93
chr7_87987383_87987655	0.35	STEAP4	STEAP family member 4	51313	0.14
chr4_152148275_152148426	0.35	SH3D19	SH3 domain containing 19	600	0.77
chrX_34673275_34673426	0.35	TMEM47	transmembrane protein 47	2055	0.5
chr5_16889789_16890008	0.35	MYO10	myosin X	26738	0.18
chr7_42147351_42147643	0.35	GLI3	GLI family zinc finger 3	119823	0.07
chr5_112582414_112582565	0.35	MCC	mutated in colorectal cancers	12115	0.27
chr9_80278787_80279042	0.35	GNA14	guanine nucleotide binding protein (G protein), alpha 14	15691	0.24
chr16_15952010_15952161	0.34	MYH11	myosin, heavy chain 11, smooth muscle	1195	0.43
chr13_54519922_54520073	0.34	ENSG00000220990	.	577906	0.0
chr1_225839301_225840394	0.34	ENAH	enabled homolog (Drosophila)	571	0.78
chr2_200604849_200605000	0.34	FTCDNL1	formiminotransferase cyclodeaminase N-terminal like	110672	0.07
chr2_65890354_65890505	0.34	ENSG00000265899	.	3961	0.34
chr20_47408037_47408263	0.34	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	36270	0.19
chr14_30664453_30664650	0.34	PRKD1	protein kinase D1	3447	0.39
chr20_49137388_49137672	0.34	PTPN1	protein tyrosine phosphatase, non-receptor type 1	10610	0.16
chr6_121756849_121757212	0.34	GJA1	gap junction protein, alpha 1, 43kDa	192	0.94
chr11_40311822_40311973	0.33	LRRC4C	leucine rich repeat containing 4C	2783	0.39
chr20_57604835_57604986	0.33	ATP5E	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit	2437	0.22
chr21_19157038_19157189	0.33	AL109761.5		8692	0.24
chr14_75478720_75478902	0.33	RP11-950C14.3		3627	0.15
chr6_165504753_165505087	0.33	C6orf118	chromosome 6 open reading frame 118	217422	0.02
chrX_13007277_13007565	0.33	TMSB4X	thymosin beta 4, X-linked	13644	0.22
chr15_92722178_92722335	0.33	RP11-24J19.1		6590	0.32
chr19_52452690_52452938	0.33	HCCAT3	hepatocellular carcinoma associated transcript 3 (non-protein coding)	399	0.77
chr1_78892388_78892539	0.33	ENSG00000212308	.	51510	0.15
chr16_65104457_65104608	0.33	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	1584	0.58
chr1_179111271_179111703	0.33	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	692	0.72
chr1_59859347_59859498	0.33	FGGY	FGGY carbohydrate kinase domain containing	83663	0.11
chr5_128796390_128797012	0.33	ADAMTS19-AS1	ADAMTS19 antisense RNA 1	319	0.77
chr10_33274227_33274378	0.33	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	7089	0.27
chr18_74200108_74200360	0.33	ZNF516	zinc finger protein 516	2501	0.24
chr2_64515395_64515553	0.33	ENSG00000264297	.	52419	0.14
chr5_59893443_59893927	0.33	DEPDC1B	DEP domain containing 1B	102276	0.07
chr1_170631765_170631991	0.33	PRRX1	paired related homeobox 1	397	0.91
chr9_12775321_12775833	0.33	LURAP1L	leucine rich adaptor protein 1-like	557	0.78
chr7_3476765_3477156	0.33	ENSG00000211544	.	18261	0.27
chr2_190244069_190244254	0.33	WDR75	WD repeat domain 75	61998	0.12
chr2_200317783_200318056	0.33	SATB2	SATB homeobox 2	2892	0.31
chr2_208549036_208549250	0.33	ENSG00000200764	.	3541	0.18
chr11_65058660_65059302	0.32	POLA2	polymerase (DNA directed), alpha 2, accessory subunit	9003	0.12
chr13_35962874_35963128	0.32	MAB21L1	mab-21-like 1 (C. elegans)	87831	0.09
chr3_89350492_89350643	0.32	EPHA3	EPH receptor A3	193741	0.03
chrX_47056761_47057047	0.32	UBA1	ubiquitin-like modifier activating enzyme 1	306	0.84
chr8_123200121_123200319	0.32	ENSG00000238901	.	483310	0.01
chr4_175075425_175075781	0.32	FBXO8	F-box protein 8	129211	0.05
chr2_175192578_175192729	0.32	SP9	Sp9 transcription factor	7021	0.17
chr2_189840264_189840425	0.32	COL3A1	collagen, type III, alpha 1	1245	0.47
chr1_94789725_94789884	0.32	ARHGAP29	Rho GTPase activating protein 29	86615	0.08
chr2_181056671_181056823	0.32	CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	184907	0.03
chr2_201270113_201270684	0.32	SPATS2L	spermatogenesis associated, serine-rich 2-like	12598	0.18
chr12_27496070_27496221	0.32	ARNTL2	aryl hydrocarbon receptor nuclear translocator-like 2	10157	0.24
chr4_157870413_157870730	0.32	PDGFC	platelet derived growth factor C	21484	0.21
chr6_45523951_45524153	0.32	ENSG00000252738	.	89789	0.09
chr9_37574334_37574485	0.32	FBXO10	F-box protein 10	1841	0.32
chr10_95241473_95241734	0.32	MYOF	myoferlin	348	0.88
chr5_35851300_35851523	0.32	IL7R	interleukin 7 receptor	1386	0.45
chr8_142141679_142142152	0.32	RP11-809O17.1		1855	0.33
chr12_59311038_59311457	0.32	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	2080	0.36
chr3_69494490_69494658	0.32	FRMD4B	FERM domain containing 4B	59144	0.16
chr3_99761156_99761307	0.31	FILIP1L	filamin A interacting protein 1-like	72126	0.09
chr7_27169269_27169568	0.31	HOXA-AS3	HOXA cluster antisense RNA 3	178	0.67
chr3_59101471_59101696	0.31	C3orf67	chromosome 3 open reading frame 67	65773	0.15
chr22_28538513_28538664	0.31	TTC28	tetratricopeptide repeat domain 28	48465	0.15
chr5_96895914_96896065	0.31	CTD-2215E18.2		358405	0.01
chr7_89058204_89058355	0.31	ENSG00000239075	.	325761	0.01
chr4_138450639_138450790	0.31	PCDH18	protocadherin 18	2851	0.43
chr6_56235163_56235375	0.31	COL21A1	collagen, type XXI, alpha 1	23623	0.2
chr4_30865130_30865281	0.31	RP11-619J20.1		69613	0.14
chr4_48024272_48024423	0.31	NIPAL1	NIPA-like domain containing 1	2797	0.23
chr7_27646157_27646308	0.31	HIBADH	3-hydroxyisobutyrate dehydrogenase	41143	0.19
chr6_42537305_42537764	0.31	UBR2	ubiquitin protein ligase E3 component n-recognin 2	5734	0.24
chr6_82707021_82707202	0.31	ENSG00000223044	.	213046	0.02
chr9_112543013_112543264	0.31	AKAP2	A kinase (PRKA) anchor protein 2	369	0.36
chr6_158461752_158461952	0.31	SYNJ2	synaptojanin 2	23355	0.18
chr5_123252700_123253101	0.31	CSNK1G3	casein kinase 1, gamma 3	328781	0.01
chr7_116909406_116909564	0.31	AC002465.2		31430	0.19
chr4_123588404_123588555	0.31	IL21	interleukin 21	46255	0.14
chr3_57042329_57042482	0.31	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	31002	0.17
chr3_98625382_98625613	0.31	ENSG00000207331	.	1806	0.32
chr5_139913473_139913662	0.31	ANKHD1	ankyrin repeat and KH domain containing 1	3407	0.11
chr13_24145710_24146057	0.31	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1080	0.66
chr3_98618999_98619299	0.31	DCBLD2	discoidin, CUB and LCCL domain containing 2	866	0.54
chr13_32859694_32859925	0.31	FRY	furry homolog (Drosophila)	2179	0.28
chr3_145879077_145879748	0.31	PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	458	0.86
chr3_179168052_179168298	0.31	GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	758	0.66
chr17_75539020_75539171	0.31	SEPT9	septin 9	61100	0.11
chr2_14633353_14633613	0.31	FAM84A	family with sequence similarity 84, member A	139327	0.05
chr5_54456050_54456451	0.31	GPX8	glutathione peroxidase 8 (putative)	252	0.86
chr10_101768167_101768400	0.31	DNMBP	dynamin binding protein	1393	0.42
chr12_66122461_66123138	0.31	HMGA2	high mobility group AT-hook 2	95112	0.08
chr22_45865037_45865472	0.30	RP1-102D24.5		20630	0.17
chr11_89113858_89114276	0.30	NOX4	NADPH oxidase 4	109833	0.07
chr8_60213383_60213534	0.30	ENSG00000201763	.	154986	0.04

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0003323	type B pancreatic cell development(GO:0003323)
0.1	0.4	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.6	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.5	GO:0060437	lung growth(GO:0060437)
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.3	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1	0.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.4	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.3	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.3	GO:0051503	adenine nucleotide transport(GO:0051503)
0.1	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.2	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.2	GO:0031223	auditory behavior(GO:0031223)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.6	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.2	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.2	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.2	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1	0.4	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.2	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.1	0.5	GO:0071320	cellular response to cAMP(GO:0071320)
0.1	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.2	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.1	0.5	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.2	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.6	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.3	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.5	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.3	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0052257	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.1	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.2	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.4	GO:0015695	organic cation transport(GO:0015695)
0.0	0.6	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0032825	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.3	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0031034	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.6	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.4	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.2	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:2001280	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.2	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.2	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.4	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.0	GO:0072194	positive regulation of smooth muscle cell differentiation(GO:0051152) kidney smooth muscle tissue development(GO:0072194)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0	0.0	GO:2000696	nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.2	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.0	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.3	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.6	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.2	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.4	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0032757	positive regulation of interleukin-8 production(GO:0032757)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.1	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.0	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.0	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.2	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.2	GO:0042554	superoxide anion generation(GO:0042554)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:1902692	regulation of neuroblast proliferation(GO:1902692)
0.0	0.0	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.0	GO:0032782	bile acid secretion(GO:0032782)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.2	GO:0007530	sex determination(GO:0007530)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.3	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.0	GO:0060579	ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.0	GO:0035850	epithelial cell differentiation involved in kidney development(GO:0035850)
0.0	0.1	GO:0090175	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.2	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.0	GO:0090103	cochlea morphogenesis(GO:0090103)
0.0	0.0	GO:0051883	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.0	GO:0048641	regulation of skeletal muscle tissue development(GO:0048641)
0.0	0.0	GO:0008218	bioluminescence(GO:0008218)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0015791	polyol transport(GO:0015791)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.0	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	1.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.4	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.1	GO:0030277	epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:2000053	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0	0.0	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:2000649	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0045598	regulation of fat cell differentiation(GO:0045598)
0.0	0.1	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.7	GO:0071437	invadopodium(GO:0071437)
0.1	0.4	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.9	GO:0005916	fascia adherens(GO:0005916)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.7	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.2	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	1.6	GO:0043292	contractile fiber(GO:0043292)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.8	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.2	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.0	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0043205	fibril(GO:0043205)
0.0	0.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.6	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.4	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	1.3	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0070052	collagen V binding(GO:0070052)
0.1	0.5	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.4	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.5	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.4	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.5	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.4	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.2	GO:0042805	actinin binding(GO:0042805)
0.0	0.4	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.2	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.5	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.3	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.3	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.2	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.7	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.0	GO:0005035	death receptor activity(GO:0005035)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.6	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.0	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	1.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.4	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.4	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.0	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.0	0.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.4	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion