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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for CEBPE_CEBPD

Z-value: 2.16

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Transcription factors associated with CEBPE_CEBPD

Gene Symbol	Gene ID	Gene Info
CEBPE Ensembl NCBI GeneCards UniProt	ENSG00000092067.5	CCAAT enhancer binding protein epsilon
CEBPD Ensembl NCBI GeneCards UniProt	ENSG00000221869.4	CCAAT enhancer binding protein delta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr8_48647847_48648063	CEBPD	3693	0.222323	0.90	1.0e-03	Click!
chr8_48648492_48649280	CEBPD	2762	0.255170	0.72	2.8e-02	Click!
chr8_48648084_48648235	CEBPD	3489	0.227586	0.60	8.7e-02	Click!
chr8_48651279_48651784	CEBPD	117	0.964335	0.56	1.1e-01	Click!
chr8_48650852_48651279	CEBPD	583	0.743280	0.45	2.2e-01	Click!
chr14_23583329_23583480	CEBPE	5421	0.108683	0.85	3.6e-03	Click!
chr14_23587780_23587931	CEBPE	970	0.379591	0.81	8.8e-03	Click!
chr14_23588022_23588173	CEBPE	728	0.496732	0.79	1.1e-02	Click!
chr14_23589888_23590039	CEBPE	1138	0.323901	0.78	1.4e-02	Click!
chr14_23589031_23589182	CEBPE	281	0.830672	0.73	2.4e-02	Click!

Activity of the CEBPE_CEBPD motif across conditions

Conditions sorted by the z-value of the CEBPE_CEBPD motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_28619412_28619563	1.22	RP11-373D23.2		195	0.87
chr17_78753891_78754042	0.86	RP11-28G8.1		25466	0.21
chr11_59950051_59950297	0.81	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	325	0.9
chr3_187607411_187607594	0.80	BCL6	B-cell CLL/lymphoma 6	143987	0.04
chr11_32852041_32852192	0.78	PRRG4	proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)	627	0.77
chr14_93540505_93540656	0.78	ITPK1-AS1	ITPK1 antisense RNA 1	6783	0.21
chr6_144357186_144358268	0.77	PLAGL1	pleiomorphic adenoma gene-like 1	28008	0.21
chr2_145444399_145444550	0.77	ZEB2	zinc finger E-box binding homeobox 2	165853	0.04
chr1_186649638_186650434	0.75	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	477	0.89
chr20_54987227_54988129	0.73	CASS4	Cas scaffolding protein family member 4	361	0.82
chr10_51575835_51576189	0.70	NCOA4	nuclear receptor coactivator 4	273	0.91
chr11_1320381_1320746	0.70	TOLLIP	toll interacting protein	3457	0.18
chr7_77168081_77168577	0.69	PTPN12	protein tyrosine phosphatase, non-receptor type 12	943	0.69
chr2_219093418_219093644	0.67	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	11598	0.11
chr2_136926324_136926475	0.65	CXCR4	chemokine (C-X-C motif) receptor 4	50664	0.17
chr8_56792958_56793527	0.65	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	848	0.55
chrX_24498632_24498874	0.65	PDK3	pyruvate dehydrogenase kinase, isozyme 3	15180	0.2
chr4_128553582_128553997	0.64	INTU	inturned planar cell polarity protein	298	0.94
chr10_77531854_77532472	0.64	C10orf11	chromosome 10 open reading frame 11	10356	0.22
chr2_152784984_152785135	0.63	CACNB4	calcium channel, voltage-dependent, beta 4 subunit	43443	0.19
chr5_36686005_36686156	0.62	CTD-2353F22.1		39195	0.2
chr8_92044308_92044459	0.61	TMEM55A	transmembrane protein 55A	8680	0.13
chr3_30673679_30673830	0.61	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	25661	0.24
chr18_53255518_53256419	0.60	TCF4	transcription factor 4	108	0.98
chr2_226983216_226983814	0.59	ENSG00000263363	.	539994	0.0
chr6_137180535_137180686	0.59	ENSG00000201807	.	3641	0.24
chr15_77861873_77862206	0.59	LINGO1	leucine rich repeat and Ig domain containing 1	62793	0.11
chr9_139439215_139440028	0.59	NOTCH1	notch 1	693	0.35
chr3_52236882_52237267	0.58	ALAS1	aminolevulinate, delta-, synthase 1	3574	0.14
chr14_99541797_99541948	0.58	AL162151.4		82881	0.1
chr15_94716341_94716492	0.57	MCTP2	multiple C2 domains, transmembrane 2	58351	0.16
chr15_42803128_42803279	0.57	SNAP23	synaptosomal-associated protein, 23kDa	842	0.51
chr17_57803272_57803423	0.57	VMP1	vacuole membrane protein 1	3729	0.21
chr7_36763519_36763817	0.57	AOAH	acyloxyacyl hydrolase (neutrophil)	386	0.9
chr17_25867508_25867659	0.56	KSR1	kinase suppressor of ras 1	42364	0.14
chr4_70579445_70579596	0.56	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	46796	0.14
chr14_21387247_21387398	0.55	RNASE3	ribonuclease, RNase A family, 3	27764	0.1
chr1_235012225_235012376	0.55	ENSG00000239690	.	27633	0.2
chr4_154582407_154582558	0.54	RP11-153M7.3		16929	0.19
chr2_174889838_174890106	0.54	SP3	Sp3 transcription factor	59542	0.15
chr9_95491243_95491394	0.53	BICD2	bicaudal D homolog 2 (Drosophila)	35776	0.15
chr4_74570333_74570484	0.53	IL8	interleukin 8	35815	0.18
chr2_113597126_113597277	0.52	IL1B	interleukin 1, beta	2721	0.23
chr18_74277400_74278128	0.52	LINC00908	long intergenic non-protein coding RNA 908	36890	0.17
chr7_29603979_29604650	0.52	PRR15	proline rich 15	752	0.51
chr16_19524952_19525190	0.51	GDE1	glycerophosphodiester phosphodiesterase 1	3419	0.15
chr17_75425897_75426048	0.51	SEPT9	septin 9	2934	0.21
chr12_122269898_122270049	0.51	RP11-7M8.2		24192	0.12
chr13_77319930_77320170	0.51	KCTD12	potassium channel tetramerization domain containing 12	140475	0.05
chr8_134258257_134258408	0.51	WISP1-OT1	WISP1 overlapping transcript 1 (non-protein coding)	17033	0.22
chr5_147845522_147845673	0.51	CTD-2283N19.1		35227	0.17
chr2_169926772_169926923	0.51	DHRS9	dehydrogenase/reductase (SDR family) member 9	761	0.69
chr1_40400191_40400342	0.51	ENSG00000207356	.	10404	0.13
chr1_16212355_16212620	0.51	SPEN	spen family transcriptional repressor	9416	0.15
chr12_76937269_76937420	0.50	OSBPL8	oxysterol binding protein-like 8	15940	0.29
chr7_50859466_50860386	0.50	GRB10	growth factor receptor-bound protein 10	740	0.77
chr11_118097499_118097650	0.50	AMICA1	adhesion molecule, interacts with CXADR antigen 1	1765	0.28
chr1_243430959_243431113	0.50	SDCCAG8	serologically defined colon cancer antigen 8	11664	0.19
chr17_592967_593118	0.49	VPS53	vacuolar protein sorting 53 homolog (S. cerevisiae)	24907	0.15
chr12_27242472_27242623	0.49	C12orf71	chromosome 12 open reading frame 71	7100	0.23
chr17_61043904_61045029	0.49	ENSG00000207552	.	22890	0.21
chr14_73928931_73929214	0.49	ENSG00000251393	.	57	0.97
chr15_63780195_63780346	0.49	USP3	ubiquitin specific peptidase 3	16523	0.23
chr1_167570877_167571161	0.49	RCSD1	RCSD domain containing 1	28311	0.15
chrX_9320798_9321168	0.48	TBL1X	transducin (beta)-like 1X-linked	110352	0.07
chr19_7799235_7799386	0.48	CLEC4G	C-type lectin domain family 4, member G	518	0.64
chr12_11803481_11804350	0.48	ETV6	ets variant 6	1127	0.62
chr16_28186650_28186801	0.47	ENSG00000200652	.	3694	0.2
chr15_64456219_64456370	0.47	PPIB	peptidylprolyl isomerase B (cyclophilin B)	890	0.54
chr8_9409853_9410128	0.47	TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	3434	0.27
chr11_63639674_63640171	0.47	MARK2	MAP/microtubule affinity-regulating kinase 2	3174	0.18
chr9_123833984_123834761	0.47	CNTRL	centriolin	2769	0.29
chr14_75920844_75920995	0.46	JDP2	Jun dimerization protein 2	22082	0.17
chr1_41326478_41326629	0.46	CITED4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4	1465	0.35
chr22_35805907_35806058	0.45	MCM5	minichromosome maintenance complex component 5	9558	0.2
chr9_134268612_134269131	0.44	PRRC2B	proline-rich coiled-coil 2B	609	0.77
chr10_4173141_4173857	0.43	KLF6	Kruppel-like factor 6	346026	0.01
chrX_15518847_15518998	0.43	BMX	BMX non-receptor tyrosine kinase	30	0.98
chr13_103333518_103333882	0.43	METTL21C	methyltransferase like 21C	13154	0.16
chr10_112033444_112033726	0.42	SMNDC1	survival motor neuron domain containing 1	30870	0.18
chr17_36715792_36715943	0.42	SRCIN1	SRC kinase signaling inhibitor 1	3793	0.19
chr12_94241991_94242142	0.42	RP11-887P2.6		12123	0.21
chr19_7710267_7710418	0.42	STXBP2	syntaxin binding protein 2	503	0.58
chr3_171779467_171780048	0.42	FNDC3B	fibronectin type III domain containing 3B	15054	0.27
chr5_147566124_147566390	0.42	SPINK6	serine peptidase inhibitor, Kazal type 6	16100	0.18
chr11_10329247_10329398	0.42	ADM	adrenomedullin	2398	0.23
chr3_66514964_66515132	0.41	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1	36308	0.22
chr13_49141961_49142410	0.40	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	34816	0.21
chr21_35917446_35917660	0.40	RCAN1	regulator of calcineurin 1	14924	0.2
chr15_78305137_78305288	0.40	TBC1D2B	TBC1 domain family, member 2B	11186	0.13
chr16_28610570_28610819	0.40	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	2264	0.2
chr16_72088411_72088562	0.40	HP	haptoglobin	5	0.51
chr19_31820042_31820193	0.40	AC007796.1		19670	0.23
chr21_36880734_36880885	0.40	ENSG00000211590	.	212204	0.02
chr10_65015927_65016153	0.39	JMJD1C	jumonji domain containing 1C	12786	0.27
chr17_80229846_80229997	0.39	CSNK1D	casein kinase 1, delta	1383	0.28
chr17_7462231_7462382	0.39	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13	202	0.78
chr1_12046097_12046354	0.39	MFN2	mitofusin 2	4176	0.15
chr16_642735_643008	0.39	RAB40C	RAB40C, member RAS oncogene family	2539	0.11
chr1_153330986_153331137	0.39	S100A9	S100 calcium binding protein A9	731	0.51
chr17_76588567_76588821	0.38	DNAH17	dynein, axonemal, heavy chain 17	15218	0.19
chr1_200558260_200558411	0.38	KIF14	kinesin family member 14	31527	0.2
chr2_185463650_185463898	0.38	ZNF804A	zinc finger protein 804A	681	0.83
chr1_36521425_36521576	0.38	TEKT2	tektin 2 (testicular)	28176	0.13
chr20_17663271_17663734	0.38	RRBP1	ribosome binding protein 1	562	0.78
chr3_98451551_98452443	0.38	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	425	0.53
chr9_140502849_140503000	0.38	ARRDC1	arrestin domain containing 1	2769	0.16
chr20_43610553_43610704	0.38	STK4	serine/threonine kinase 4	15461	0.14
chr2_124667522_124667673	0.38	ENSG00000223118	.	40450	0.2
chr10_111827720_111827871	0.37	ADD3	adducin 3 (gamma)	60073	0.12
chr15_42349751_42349902	0.37	PLA2G4E	phospholipase A2, group IVE	6438	0.17
chr1_38317055_38317206	0.37	MTF1	metal-regulatory transcription factor 1	8162	0.1
chr1_180982364_180982515	0.37	STX6	syntaxin 6	9566	0.16
chr3_72944167_72944405	0.37	GXYLT2	glucoside xylosyltransferase 2	7062	0.24
chr10_47670479_47670739	0.37	ANTXRL	anthrax toxin receptor-like	12360	0.2
chr17_73089180_73089331	0.37	SLC16A5	solute carrier family 16 (monocarboxylate transporter), member 5	127	0.91
chr21_44035208_44035359	0.36	AP001626.2		36071	0.13
chr12_49628889_49629058	0.36	TUBA1C	tubulin, alpha 1c	7264	0.13
chr2_64500730_64500881	0.36	AC074289.1		45203	0.16
chr8_22961570_22961743	0.36	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	1222	0.37
chr5_40678717_40679405	0.36	PTGER4	prostaglandin E receptor 4 (subtype EP4)	539	0.8
chr17_38269362_38269513	0.36	MSL1	male-specific lethal 1 homolog (Drosophila)	9114	0.11
chr5_49944181_49944332	0.36	PARP8	poly (ADP-ribose) polymerase family, member 8	17477	0.3
chr2_123738319_123738470	0.36	ENSG00000221689	.	701397	0.0
chr17_40463640_40463791	0.36	STAT5A	signal transducer and activator of transcription 5A	5527	0.14
chr3_146260050_146260212	0.36	PLSCR1	phospholipid scramblase 1	2177	0.31
chr15_80271248_80271486	0.36	BCL2A1	BCL2-related protein A1	7579	0.2
chr7_79408525_79408693	0.36	ENSG00000200786	.	125184	0.06
chr1_26662362_26662902	0.35	AIM1L	absent in melanoma 1-like	3205	0.15
chr1_87796860_87797240	0.35	LMO4	LIM domain only 4	301	0.95
chr20_58513678_58513898	0.35	PPP1R3D	protein phosphatase 1, regulatory subunit 3D	1564	0.28
chr18_74872659_74872810	0.35	MBP	myelin basic protein	27934	0.24
chr18_9779691_9779842	0.35	ENSG00000242651	.	50858	0.12
chr12_89746565_89746947	0.35	DUSP6	dual specificity phosphatase 6	292	0.94
chr2_219671245_219671396	0.35	CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	683	0.61
chr10_125851443_125851830	0.35	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	334	0.93
chr3_58320901_58321052	0.35	PXK	PX domain containing serine/threonine kinase	1943	0.34
chr1_27951756_27951907	0.35	FGR	feline Gardner-Rasheed sarcoma viral oncogene homolog	815	0.54
chr7_115671621_115671772	0.35	TFEC	transcription factor EC	829	0.76
chr2_29175549_29175700	0.34	FAM179A	family with sequence similarity 179, member A	3853	0.14
chr6_134343019_134343170	0.34	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12	30680	0.19
chr4_113066984_113067681	0.34	C4orf32	chromosome 4 open reading frame 32	779	0.73
chr17_25609205_25609356	0.34	ENSG00000263583	.	11742	0.23
chr4_86396251_86396726	0.34	ARHGAP24	Rho GTPase activating protein 24	97	0.99
chr6_146867809_146867960	0.34	RAB32	RAB32, member RAS oncogene family	3055	0.34
chr9_21023989_21024197	0.34	PTPLAD2	protein tyrosine phosphatase-like A domain containing 2	7515	0.22
chr4_157115087_157115238	0.34	ENSG00000221189	.	102636	0.08
chr13_48736574_48736800	0.34	MED4	mediator complex subunit 4	67420	0.1
chr10_3710614_3710914	0.34	RP11-184A2.3		82495	0.1
chr16_4103676_4103973	0.33	RP11-462G12.4		21811	0.19
chr17_55980824_55981073	0.33	CUEDC1	CUE domain containing 1	198	0.94
chr19_52239080_52239231	0.33	HAS1	hyaluronan synthase 1	11908	0.1
chr8_20057882_20058033	0.33	ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	3007	0.25
chr8_17193981_17194132	0.32	MTMR7	myotubularin related protein 7	24874	0.21
chr8_129262697_129262848	0.32	ENSG00000201782	.	30022	0.23
chr17_76912321_76912483	0.32	TIMP2	TIMP metallopeptidase inhibitor 2	6081	0.15
chr3_120277883_120278034	0.32	NDUFB4	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa	37198	0.19
chr16_11678014_11678655	0.32	LITAF	lipopolysaccharide-induced TNF factor	1895	0.35
chr3_43221570_43221860	0.32	ENSG00000222331	.	30648	0.18
chr13_110357339_110357490	0.32	LINC00676	long intergenic non-protein coding RNA 676	23215	0.26
chr12_81102183_81102935	0.32	MYF6	myogenic factor 6 (herculin)	1282	0.49
chr4_106035170_106035321	0.32	ENSG00000252136	.	8101	0.23
chr15_57595155_57595306	0.32	TCF12	transcription factor 12	20577	0.2
chr13_48796681_48797014	0.32	ITM2B	integral membrane protein 2B	10447	0.26
chr2_163199250_163199401	0.32	GCA	grancalcin, EF-hand calcium binding protein	1273	0.52
chr9_126629276_126629488	0.32	DENND1A	DENN/MADD domain containing 1A	63004	0.12
chr12_68758221_68758372	0.32	MDM1	Mdm1 nuclear protein homolog (mouse)	32135	0.22
chr15_65277376_65277561	0.31	SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	2346	0.25
chr17_77789018_77789210	0.31	ENSG00000238331	.	4636	0.15
chr5_43040634_43042182	0.31	AC025171.1		269	0.87
chr2_74765980_74766272	0.31	HTRA2	HtrA serine peptidase 2	8953	0.07
chr8_12615101_12615641	0.31	LONRF1	LON peptidase N-terminal domain and ring finger 1	2372	0.31
chr11_104904746_104905919	0.31	CASP1	caspase 1, apoptosis-related cysteine peptidase	508	0.77
chr12_123376332_123377156	0.31	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)	2038	0.29
chr8_26370640_26370791	0.30	PNMA2	paraneoplastic Ma antigen 2	893	0.46
chr6_53661674_53661825	0.30	LRRC1	leucine rich repeat containing 1	1861	0.34
chr10_99223651_99223802	0.30	MMS19	MMS19 nucleotide excision repair homolog (S. cerevisiae)	3556	0.12
chr9_94184850_94185394	0.30	NFIL3	nuclear factor, interleukin 3 regulated	1022	0.67
chr3_172240144_172241280	0.30	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	553	0.83
chr3_171788685_171788836	0.30	FNDC3B	fibronectin type III domain containing 3B	24057	0.25
chr14_21738093_21738425	0.29	HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	606	0.71
chr11_48075840_48075991	0.29	AC103828.1		38508	0.15
chr3_59119295_59119446	0.29	C3orf67	chromosome 3 open reading frame 67	83560	0.11
chr15_93460792_93461223	0.29	CHD2	chromodomain helicase DNA binding protein 2	13304	0.19
chr1_109913452_109914259	0.29	SORT1	sortilin 1	22124	0.14
chr22_48554335_48554486	0.29	ENSG00000266508	.	115766	0.07
chr2_143904464_143904615	0.29	ARHGAP15	Rho GTPase activating protein 15	17656	0.23
chr8_126503508_126503659	0.29	ENSG00000266452	.	46776	0.17
chr13_33001190_33001359	0.29	N4BP2L1	NEDD4 binding protein 2-like 1	877	0.62
chr7_106807796_106808590	0.29	HBP1	HMG-box transcription factor 1	1213	0.5
chr2_85815414_85815565	0.29	VAMP5	vesicle-associated membrane protein 5	3958	0.1
chr17_26385024_26385175	0.28	ENSG00000252283	.	3894	0.19
chr6_112194486_112194668	0.28	FYN	FYN oncogene related to SRC, FGR, YES	50	0.99
chr9_128521797_128522422	0.28	PBX3	pre-B-cell leukemia homeobox 3	11631	0.27
chr10_17259722_17259873	0.28	VIM-AS1	VIM antisense RNA 1	9100	0.16
chr10_27736608_27736759	0.28	PTCHD3	patched domain containing 3	33386	0.18
chr11_46378662_46378813	0.28	DGKZ	diacylglycerol kinase, zeta	4408	0.16
chr8_30581756_30582064	0.28	GSR	glutathione reductase	2617	0.31
chr2_201987732_201987883	0.28	CFLAR	CASP8 and FADD-like apoptosis regulator	607	0.65
chr3_101568772_101569567	0.28	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	62	0.98

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPE_CEBPD

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0031394	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	0.6	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.5	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.1	0.4	GO:0001821	histamine secretion(GO:0001821)
0.1	0.3	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.4	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.2	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.5	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.1	0.2	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.2	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.3	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.1	0.2	GO:0009405	pathogenesis(GO:0009405)
0.1	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	0.2	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.3	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.1	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.2	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.2	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.2	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0021554	optic nerve development(GO:0021554)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.1	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.2	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.2	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.0	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.1	GO:0052553	modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0032770	positive regulation of monooxygenase activity(GO:0032770)
0.0	0.2	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0060872	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0	0.2	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.2	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.4	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.2	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.2	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0090195	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.3	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.2	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.3	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
0.0	0.1	GO:0060039	pericardium development(GO:0060039)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.2	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.9	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.5	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0043300	regulation of leukocyte degranulation(GO:0043300)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.4	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.2	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.3	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.3	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.2	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.7	GO:0061025	membrane fusion(GO:0061025)
0.0	0.1	GO:2000258	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.2	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.1	GO:0032782	canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0090312	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.0	GO:0044650	virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.3	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.0	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0015791	polyol transport(GO:0015791)
0.0	0.1	GO:0006278	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.3	GO:0001843	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.0	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.0	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.3	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0001510	RNA methylation(GO:0001510)
0.0	0.2	GO:0050999	regulation of nitric-oxide synthase activity(GO:0050999)
0.0	0.0	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0	0.0	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.0	GO:0032202	telomere assembly(GO:0032202)
0.0	0.1	GO:0006907	pinocytosis(GO:0006907)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.3	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.4	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.2	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.2	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	1.1	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.0	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.4	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.0	GO:0034706	sodium channel complex(GO:0034706)
0.0	1.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.0	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0031201	SNARE complex(GO:0031201)
0.0	0.0	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2	0.5	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.6	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.2	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.5	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.4	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.3	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1	0.6	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.1	0.3	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.3	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.3	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.4	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	1.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.4	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.8	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.6	GO:0016684	peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0051192	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.4	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.3	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.5	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.3	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.4	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.2	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.4	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.0	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.0	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.2	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
1.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.9	PID TRAIL PATHWAY	TRAIL signaling pathway
0.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.7	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
1.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.3	PID INSULIN PATHWAY	Insulin Pathway
0.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.3	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.7	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.6	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling

Results for CEBPE_CEBPD

Z-value: 2.16

Motif logo

Transcription factors associated with CEBPE_CEBPD

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the CEBPE_CEBPD motif across conditions

Conditions sorted by the z-value of the CEBPE_CEBPD motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPE_CEBPD

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: