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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CEBPG

Z-value: 1.03

Motif logo

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Transcription factors associated with CEBPG

Gene Symbol Gene ID Gene Info
ENSG00000153879.4 CEBPG

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
CEBPGchr19_33866567_3386680414670.4267030.751.9e-02Click!
CEBPGchr19_33865170_338657862600.924510-0.713.1e-02Click!
CEBPGchr19_33867678_3386782925350.2929840.713.1e-02Click!
CEBPGchr19_33870618_3387076954750.2208990.608.7e-02Click!
CEBPGchr19_33885155_33885306200120.1888370.511.6e-01Click!

Activity of the CEBPG motif across conditions

Conditions sorted by the z-value of the CEBPG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_56792958_56793527 0.63 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
848
0.55
chr11_78271810_78272407 0.56 NARS2
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
12467
0.18
chr17_64464860_64465690 0.54 RP11-4F22.2

52303
0.15
chr4_105982764_105983024 0.51 ENSG00000252136
.
44250
0.17
chr18_74179382_74179755 0.44 ZNF516
zinc finger protein 516
23167
0.16
chr7_37771982_37772133 0.42 GPR141
G protein-coupled receptor 141
7939
0.27
chr12_81102183_81102935 0.41 MYF6
myogenic factor 6 (herculin)
1282
0.49
chr2_201958459_201958610 0.40 ENSG00000252148
.
13969
0.12
chr4_157692811_157693135 0.39 RP11-154F14.2

69538
0.11
chr2_238889404_238889624 0.39 UBE2F
ubiquitin-conjugating enzyme E2F (putative)
7777
0.21
chr19_49864989_49865626 0.38 DKKL1
dickkopf-like 1
267
0.51
chr12_52427316_52427521 0.38 NR4A1
nuclear receptor subfamily 4, group A, member 1
3543
0.16
chr13_27334023_27334664 0.38 GPR12
G protein-coupled receptor 12
84
0.98
chr20_19983837_19984098 0.37 NAA20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
13793
0.21
chr11_35949210_35949523 0.37 RP11-698N11.2

9077
0.19
chr7_155446675_155446826 0.36 RBM33
RNA binding motif protein 33
9354
0.22
chr5_94417062_94417734 0.36 MCTP1
multiple C2 domains, transmembrane 1
48
0.99
chr10_14606601_14606845 0.36 FAM107B
family with sequence similarity 107, member B
7306
0.26
chr7_33089731_33090334 0.36 ENSG00000241420
.
4330
0.18
chr2_163199250_163199401 0.36 GCA
grancalcin, EF-hand calcium binding protein
1273
0.52
chr15_99192776_99194432 0.34 IGF1R
insulin-like growth factor 1 receptor
1331
0.47
chr3_11758192_11758601 0.34 VGLL4
vestigial like 4 (Drosophila)
2672
0.38
chr15_70052729_70052912 0.34 ENSG00000215958
.
25023
0.21
chr20_45980052_45980426 0.34 ZMYND8
zinc finger, MYND-type containing 8
382
0.71
chr11_63639674_63640171 0.33 MARK2
MAP/microtubule affinity-regulating kinase 2
3174
0.18
chr2_226983216_226983814 0.33 ENSG00000263363
.
539994
0.0
chr5_58592476_58593460 0.32 PDE4D
phosphodiesterase 4D, cAMP-specific
21023
0.29
chr2_230271788_230271939 0.32 PID1
phosphotyrosine interaction domain containing 1
135862
0.05
chr5_153424892_153425043 0.32 MFAP3
microfibrillar-associated protein 3
6408
0.22
chr15_83501820_83502050 0.32 HOMER2
homer homolog 2 (Drosophila)
16544
0.13
chr19_33790953_33791293 0.32 CTD-2540B15.11

283
0.79
chr10_51575835_51576189 0.31 NCOA4
nuclear receptor coactivator 4
273
0.91
chr11_59319331_59319576 0.31 ENSG00000252893
.
6820
0.14
chr1_36500237_36500507 0.31 RP4-665N4.8

21141
0.16
chr5_53813164_53813315 0.31 SNX18
sorting nexin 18
350
0.92
chr18_9673690_9673841 0.31 RAB31
RAB31, member RAS oncogene family
34397
0.15
chr9_93564472_93565060 0.31 SYK
spleen tyrosine kinase
557
0.87
chr19_16259637_16259788 0.31 HSH2D
hematopoietic SH2 domain containing
5166
0.13
chr7_12609670_12609821 0.31 SCIN
scinderin
567
0.7
chr9_110495286_110496024 0.30 AL162389.1
Uncharacterized protein
44764
0.15
chr1_108479342_108479642 0.30 VAV3-AS1
VAV3 antisense RNA 1
27573
0.19
chr9_89952337_89952906 0.30 ENSG00000212421
.
77256
0.11
chr10_111827720_111827871 0.30 ADD3
adducin 3 (gamma)
60073
0.12
chr10_17241830_17242242 0.30 TRDMT1
tRNA aspartic acid methyltransferase 1
1543
0.37
chr11_46181275_46181426 0.30 PHF21A
PHD finger protein 21A
38365
0.15
chr2_63287244_63287598 0.30 OTX1
orthodenticle homeobox 1
9484
0.23
chr1_12046097_12046354 0.30 MFN2
mitofusin 2
4176
0.15
chr2_64500730_64500881 0.29 AC074289.1

45203
0.16
chr10_3814711_3815005 0.29 RP11-184A2.2

4751
0.24
chr10_5491792_5492244 0.28 NET1
neuroepithelial cell transforming 1
3444
0.22
chr3_4026218_4026369 0.28 LRRN1
leucine rich repeat neuronal 1
185172
0.03
chr1_94882933_94883167 0.27 ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
883
0.72
chr5_88178054_88178448 0.27 MEF2C
myocyte enhancer factor 2C
713
0.52
chr1_221247887_221248144 0.27 HLX
H2.0-like homeobox
193431
0.03
chr13_48796681_48797014 0.27 ITM2B
integral membrane protein 2B
10447
0.26
chr22_39808489_39808802 0.27 TAB1
TGF-beta activated kinase 1/MAP3K7 binding protein 1
12856
0.15
chr6_25003002_25003351 0.26 ENSG00000244618
.
28334
0.16
chr1_42230520_42230906 0.26 ENSG00000264896
.
5901
0.3
chr2_851043_851194 0.26 AC113607.3

65692
0.12
chr9_110310779_110311295 0.26 KLF4
Kruppel-like factor 4 (gut)
58274
0.13
chr21_45509274_45509425 0.26 PWP2
PWP2 periodic tryptophan protein homolog (yeast)
17822
0.16
chrX_18686331_18686482 0.26 RS1
retinoschisin 1
3823
0.25
chr2_176971683_176972255 0.26 HOXD11
homeobox D11
45
0.92
chr10_26985869_26986716 0.26 PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
296
0.92
chr7_2851005_2851785 0.25 GNA12
guanine nucleotide binding protein (G protein) alpha 12
3497
0.32
chr15_68497324_68497660 0.25 CALML4
calmodulin-like 4
334
0.87
chr20_58547296_58547466 0.25 CDH26
cadherin 26
13899
0.17
chr19_8750057_8750208 0.25 ACTL9
actin-like 9
59040
0.09
chr17_68166405_68166607 0.25 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
830
0.45
chr9_128521797_128522422 0.24 PBX3
pre-B-cell leukemia homeobox 3
11631
0.27
chr5_77784955_77785106 0.24 LHFPL2
lipoma HMGIC fusion partner-like 2
59944
0.15
chr8_123256270_123256596 0.24 ENSG00000238901
.
427097
0.01
chr8_26288224_26288375 0.24 RP11-14I17.2

8190
0.19
chr8_16689434_16690090 0.24 ENSG00000264092
.
31243
0.24
chr11_116856860_116857090 0.24 SIK3
SIK family kinase 3
29215
0.13
chr5_16509247_16509418 0.24 FAM134B
family with sequence similarity 134, member B
225
0.95
chr7_27290832_27290983 0.24 EVX1-AS
EVX1 antisense RNA
4059
0.14
chr4_84161720_84161871 0.23 COQ2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
44123
0.16
chr19_4374282_4374693 0.23 SH3GL1
SH3-domain GRB2-like 1
5802
0.08
chr9_124261192_124261996 0.23 ENSG00000240299
.
4797
0.23
chr9_70850276_70850542 0.23 CBWD3
COBW domain containing 3
5988
0.18
chr10_101605795_101606213 0.23 DNMBP
dynamin binding protein
52015
0.12
chr3_138892567_138893067 0.23 MRPS22
mitochondrial ribosomal protein S22
63571
0.12
chr5_173334437_173334588 0.23 CPEB4
cytoplasmic polyadenylation element binding protein 4
14431
0.25
chr16_21620226_21620509 0.23 METTL9
methyltransferase like 9
3054
0.17
chr12_10874089_10875353 0.23 YBX3
Y box binding protein 3
1185
0.46
chr19_38756015_38756259 0.23 SPINT2
serine peptidase inhibitor, Kunitz type, 2
159
0.9
chr14_67709110_67709261 0.23 MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
841
0.64
chr5_154145914_154146065 0.23 LARP1
La ribonucleoprotein domain family, member 1
9255
0.18
chr5_148207768_148208716 0.23 ADRB2
adrenoceptor beta 2, surface
2086
0.43
chr5_26247860_26248011 0.23 ENSG00000222560
.
234937
0.02
chr7_28705588_28705739 0.23 CREB5
cAMP responsive element binding protein 5
19935
0.29
chr16_89600841_89601123 0.22 ENSG00000252579
.
1020
0.38
chr7_139561657_139561808 0.22 TBXAS1
thromboxane A synthase 1 (platelet)
32622
0.21
chr5_52775201_52775957 0.22 FST
follistatin
660
0.81
chr14_51289214_51289365 0.22 NIN
ninein (GSK3B interacting protein)
515
0.52
chr8_126290495_126290646 0.22 ENSG00000242170
.
7724
0.27
chr5_119542834_119542985 0.22 ENSG00000251975
.
130439
0.06
chr17_1458782_1458933 0.22 PITPNA
phosphatidylinositol transfer protein, alpha
2491
0.19
chr1_61668583_61669016 0.22 RP4-802A10.1

78394
0.11
chr10_1090354_1090600 0.22 ENSG00000238924
.
2182
0.2
chr6_88407613_88407764 0.22 AKIRIN2
akirin 2
4239
0.23
chr3_171780331_171780482 0.22 FNDC3B
fibronectin type III domain containing 3B
15703
0.27
chr7_70201396_70202343 0.22 AUTS2
autism susceptibility candidate 2
7744
0.34
chr4_172263864_172264142 0.22 ENSG00000251961
.
451385
0.01
chr4_91348946_91349097 0.22 ENSG00000252087
.
57747
0.17
chr16_53899292_53899443 0.22 FTO
fat mass and obesity associated
21462
0.24
chr4_120291951_120292186 0.22 ENSG00000201186
.
3351
0.26
chr8_32165347_32165498 0.22 ENSG00000200246
.
51410
0.15
chr6_133034939_133035106 0.21 VNN1
vanin 1
166
0.94
chr2_147579520_147579813 0.21 ENSG00000238860
.
501873
0.0
chr11_18414110_18414261 0.21 LDHA
lactate dehydrogenase A
1750
0.24
chr12_68383944_68384095 0.21 IFNG-AS1
IFNG antisense RNA 1
710
0.81
chr11_112033943_112034120 0.21 IL18
interleukin 18 (interferon-gamma-inducing factor)
766
0.47
chr4_48240161_48240435 0.21 TEC
tec protein tyrosine kinase
31583
0.18
chr18_2848081_2848464 0.21 EMILIN2
elastin microfibril interfacer 2
1244
0.42
chr1_185688405_185688780 0.21 HMCN1
hemicentin 1
15091
0.26
chr4_70617052_70617203 0.21 SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
9189
0.25
chr19_14224361_14224512 0.21 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
564
0.58
chr10_4284322_4284712 0.21 ENSG00000207124
.
272627
0.02
chr11_133666002_133666153 0.21 SPATA19
spermatogenesis associated 19
49319
0.16
chr16_3309300_3309451 0.21 MEFV
Mediterranean fever
2748
0.14
chr10_73585587_73585738 0.21 ENSG00000238446
.
18889
0.16
chr14_73928931_73929214 0.21 ENSG00000251393
.
57
0.97
chr3_134050593_134051228 0.21 AMOTL2
angiomotin like 2
39844
0.16
chr14_65104571_65104722 0.21 RP11-973N13.3

41392
0.13
chr17_49163006_49163241 0.21 ENSG00000238815
.
12516
0.16
chr9_130399731_130400130 0.21 STXBP1
syntaxin binding protein 1
25362
0.12
chr2_51447556_51447707 0.20 NRXN1
neurexin 1
187957
0.03
chr21_18348624_18348775 0.20 ENSG00000239023
.
257382
0.02
chr6_137555835_137556144 0.20 IFNGR1
interferon gamma receptor 1
15403
0.25
chr2_40907638_40908036 0.20 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
69644
0.14
chr1_234737377_234737528 0.20 RP4-781K5.2

5302
0.2
chr15_90709177_90709401 0.20 ENSG00000240470
.
176
0.92
chr6_37093616_37093837 0.20 PIM1
pim-1 oncogene
44253
0.13
chr8_120221581_120221782 0.20 MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
1071
0.66
chr6_144357186_144358268 0.20 PLAGL1
pleiomorphic adenoma gene-like 1
28008
0.21
chr5_88122444_88122620 0.20 MEF2C
myocyte enhancer factor 2C
443
0.88
chr3_171788685_171788836 0.20 FNDC3B
fibronectin type III domain containing 3B
24057
0.25
chr1_233393657_233393808 0.20 PCNXL2
pecanex-like 2 (Drosophila)
30717
0.22
chr5_49738485_49738636 0.20 EMB
embigin
1359
0.62
chr22_36231755_36232301 0.20 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
4237
0.32
chr3_151608868_151609019 0.20 SUCNR1
succinate receptor 1
17512
0.21
chr11_25264958_25265109 0.20 ENSG00000265837
.
293791
0.01
chr15_94796649_94796923 0.20 MCTP2
multiple C2 domains, transmembrane 2
22019
0.29
chr13_110746963_110747216 0.20 ENSG00000265885
.
3409
0.37
chr1_190210847_190210998 0.20 RP11-547I7.1

23106
0.29
chr1_206553298_206553661 0.20 SRGAP2-AS1
SRGAP2 antisense RNA 1
1475
0.4
chr1_40400191_40400342 0.20 ENSG00000207356
.
10404
0.13
chr13_49788937_49789202 0.20 MLNR
motilin receptor
5405
0.25
chr12_113900471_113900622 0.20 RP11-82C23.2

9262
0.16
chr14_107075724_107075875 0.20 IGHV3-57
immunoglobulin heavy variable 3-57 (pseudogene)
613
0.3
chr22_30591687_30592196 0.19 RP3-438O4.4

11157
0.14
chr10_99444807_99445034 0.19 AVPI1
arginine vasopressin-induced 1
2160
0.25
chr4_95489578_95489729 0.19 PDLIM5
PDZ and LIM domain 5
44777
0.21
chr12_6495821_6496120 0.19 LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
1685
0.24
chr6_81964027_81964178 0.19 RP1-300G12.2

280528
0.01
chr15_101273643_101273824 0.19 ENSG00000212306
.
95165
0.07
chr2_143904464_143904615 0.19 ARHGAP15
Rho GTPase activating protein 15
17656
0.23
chr2_145216263_145216593 0.19 ZEB2
zinc finger E-box binding homeobox 2
28291
0.23
chr3_152884468_152884748 0.19 RAP2B
RAP2B, member of RAS oncogene family
4579
0.23
chr2_10520029_10520465 0.19 HPCAL1
hippocalcin-like 1
39900
0.14
chr4_30727938_30728161 0.19 PCDH7
protocadherin 7
4072
0.35
chr2_196281841_196281992 0.19 ENSG00000202206
.
96844
0.09
chr5_34001934_34002085 0.19 AMACR
alpha-methylacyl-CoA racemase
6124
0.2
chr7_129493207_129493836 0.19 ENSG00000207691
.
78667
0.06
chr12_70132575_70133879 0.19 RAB3IP
RAB3A interacting protein
47
0.95
chr16_53241926_53242320 0.19 CHD9
chromodomain helicase DNA binding protein 9
222
0.94
chr11_27416621_27416772 0.19 CCDC34
coiled-coil domain containing 34
31281
0.18
chr3_36937026_36937306 0.19 TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
36792
0.17
chr10_26779779_26779930 0.19 ENSG00000199733
.
18664
0.24
chr6_66730963_66731114 0.19 EYS
eyes shut homolog (Drosophila)
313920
0.01
chr20_5260387_5260538 0.19 PROKR2
prokineticin receptor 2
34553
0.17
chr1_64013670_64013821 0.19 DLEU2L
deleted in lymphocytic leukemia 2-like
843
0.52
chr12_12491368_12491613 0.19 MANSC1
MANSC domain containing 1
118
0.96
chr8_126232454_126232605 0.19 ENSG00000242170
.
50317
0.15
chr3_73633983_73634134 0.19 ENSG00000239119
.
9095
0.22
chr1_164529222_164529675 0.19 PBX1
pre-B-cell leukemia homeobox 1
388
0.91
chr6_130004791_130005136 0.19 ARHGAP18
Rho GTPase activating protein 18
26407
0.23
chr1_33428156_33429049 0.19 RNF19B
ring finger protein 19B
1684
0.28
chr3_60994671_60994822 0.19 ENSG00000212211
.
152469
0.05
chr5_97446035_97446186 0.19 ENSG00000223053
.
528825
0.0
chr1_36521425_36521576 0.19 TEKT2
tektin 2 (testicular)
28176
0.13
chr3_187607411_187607594 0.18 BCL6
B-cell CLL/lymphoma 6
143987
0.04
chr1_224618149_224618304 0.18 WDR26
WD repeat domain 26
3581
0.24
chr2_235275710_235275861 0.18 ARL4C
ADP-ribosylation factor-like 4C
129459
0.06
chr6_82522367_82522541 0.18 ENSG00000206886
.
48713
0.15
chr21_30472506_30472657 0.18 MAP3K7CL
MAP3K7 C-terminal like
8006
0.14
chr7_38670068_38671048 0.18 AMPH
amphiphysin
462
0.87
chr15_58622989_58623389 0.18 ALDH1A2
aldehyde dehydrogenase 1 family, member A2
51727
0.15
chr4_100737483_100737634 0.18 DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
432
0.88
chr5_147566124_147566390 0.18 SPINK6
serine peptidase inhibitor, Kazal type 6
16100
0.18
chr19_30714107_30714258 0.18 ZNF536
zinc finger protein 536
5239
0.26
chrX_20413264_20413415 0.18 ENSG00000252978
.
56887
0.16
chr3_75291615_75291766 0.18 ENSG00000266780
.
28063
0.21
chr15_47476270_47477144 0.18 SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
409
0.87
chr3_43591104_43591255 0.18 ANO10
anoctamin 10
5724
0.29
chr1_207509019_207509170 0.18 CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
13958
0.26
chr18_74205501_74206173 0.18 ZNF516
zinc finger protein 516
1309
0.32
chrX_68063428_68063579 0.18 EFNB1
ephrin-B1
14663
0.3

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of CEBPG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001821 histamine secretion(GO:0001821)
0.1 0.7 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.3 GO:0032632 interleukin-3 production(GO:0032632)
0.1 0.3 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.1 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0010996 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.2 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:2001280 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0003171 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.3 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0061430 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.3 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.0 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0051788 response to misfolded protein(GO:0051788)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.1 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.4 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0010894 negative regulation of steroid biosynthetic process(GO:0010894)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.0 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.7 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.0 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.1 GO:0055057 neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0 0.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 0.3 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.1 GO:0046033 AMP metabolic process(GO:0046033)
0.0 0.0 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.0 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.0 GO:2000649 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.0 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0043205 fibril(GO:0043205)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0043256 laminin complex(GO:0043256)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0001940 male pronucleus(GO:0001940)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.5 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.0 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol