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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for CENPB

Z-value: 1.80

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Transcription factors associated with CENPB

Gene Symbol	Gene ID	Gene Info
CENPB Ensembl NCBI GeneCards UniProt	ENSG00000125817.7	centromere protein B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr20_3766791_3767143	CENPB	370	0.599371	0.69	3.8e-02	Click!
chr20_3764841_3764992	CENPB	2421	0.161262	0.44	2.4e-01	Click!
chr20_3766238_3766588	CENPB	924	0.348276	0.39	3.0e-01	Click!
chr20_3765290_3765684	CENPB	1850	0.197140	0.37	3.3e-01	Click!
chr20_3765918_3766170	CENPB	1293	0.264619	0.36	3.4e-01	Click!

Activity of the CENPB motif across conditions

Conditions sorted by the z-value of the CENPB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_83378387_83378599	0.72	AP3B2	adaptor-related protein complex 3, beta 2 subunit	38	0.96
chr9_116102276_116102560	0.67	WDR31	WD repeat domain 31	116	0.95
chr5_60921640_60922072	0.66	C5orf64	chromosome 5 open reading frame 64	11780	0.22
chr2_204735072_204735223	0.57	CTLA4	cytotoxic T-lymphocyte-associated protein 4	192	0.96
chr4_42401015_42401166	0.55	SHISA3	shisa family member 3	1234	0.51
chr20_52790515_52790830	0.54	CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	160	0.97
chr3_38496116_38496319	0.54	ACVR2B-AS1	ACVR2B antisense RNA 1	94	0.93
chr8_130838389_130838591	0.52	RP11-473O4.5		6057	0.23
chr10_89621181_89621332	0.51	PTEN	phosphatase and tensin homolog	1614	0.26
chr11_66233385_66233536	0.50	PELI3	pellino E3 ubiquitin protein ligase family member 3	756	0.42
chr19_17008131_17008363	0.48	CPAMD8	C3 and PZP-like, alpha-2-macroglobulin domain containing 8	1221	0.33
chr2_20251239_20251427	0.46	LAPTM4A	lysosomal protein transmembrane 4 alpha	456	0.53
chr6_1885704_1885932	0.46	FOXC1	forkhead box C1	275137	0.01
chr22_31502736_31502961	0.46	SELM	Selenoprotein M	706	0.53
chr17_59285555_59285706	0.46	RP11-136H19.1		72305	0.1
chr2_233791696_233791935	0.45	NGEF	neuronal guanine nucleotide exchange factor	1049	0.54
chr2_33172704_33172929	0.45	LTBP1	latent transforming growth factor beta binding protein 1	447	0.82
chr1_85724953_85725320	0.45	C1orf52	chromosome 1 open reading frame 52	180	0.92
chr21_45661777_45662023	0.45	ICOSLG	inducible T-cell co-stimulator ligand	1051	0.37
chr10_104194159_104194310	0.44	CUEDC2	CUE domain containing 2	1816	0.17
chr22_16192555_16192736	0.44	LL22NC03-N64E9.1		11641	0.18
chr17_62658263_62658426	0.43	SMURF2	SMAD specific E3 ubiquitin protein ligase 2	158	0.96
chr9_15511271_15511422	0.43	PSIP1	PC4 and SFRS1 interacting protein 1	329	0.87
chr1_151763327_151763716	0.43	RP11-98D18.9		203	0.63
chr1_1135870_1136021	0.43	TNFRSF18	tumor necrosis factor receptor superfamily, member 18	5115	0.08
chr2_238876111_238876470	0.42	UBE2F	ubiquitin-conjugating enzyme E2F (putative)	566	0.79
chr3_58224088_58224320	0.42	ABHD6	abhydrolase domain containing 6	55	0.98
chr3_57542507_57542919	0.42	PDE12	phosphodiesterase 12	709	0.52
chr16_50581926_50582116	0.42	NKD1	naked cuticle homolog 1 (Drosophila)	220	0.93
chr5_95157288_95157503	0.41	GLRX	glutaredoxin (thioltransferase)	1020	0.47
chr16_2827744_2828043	0.41	TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	595	0.5
chr10_179263_179512	0.40	ZMYND11	zinc finger, MYND-type containing 11	1018	0.6
chr20_61425995_61426159	0.40	MRGBP	MRG/MORF4L binding protein	1728	0.23
chr1_168329622_168329773	0.40	ENSG00000207974	.	15065	0.23
chr3_152878700_152878913	0.40	RP11-529G21.2		758	0.56
chr11_65222025_65222643	0.40	AP000769.1	Uncharacterized protein	394	0.78
chr5_176023977_176024277	0.40	GPRIN1	G protein regulated inducer of neurite outgrowth 1	13007	0.11
chr9_136932210_136932418	0.39	BRD3	bromodomain containing 3	778	0.61
chr13_107519622_107519843	0.39	ENSG00000239050	.	107642	0.08
chr1_202996029_202996239	0.39	PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	508	0.72
chr17_2907702_2908042	0.39	CTD-3060P21.1		38683	0.15
chr5_34915226_34915588	0.39	BRIX1	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)	74	0.96
chr12_110905736_110905986	0.39	GPN3	GPN-loop GTPase 3	208	0.6
chr8_33330699_33330850	0.38	FUT10	fucosyltransferase 10 (alpha (1,3) fucosyltransferase)	110	0.96
chr11_62599289_62599501	0.38	STX5	syntaxin 5	118	0.68
chr17_66288077_66288331	0.38	ARSG	arylsulfatase G	545	0.56
chr18_268178_268573	0.38	THOC1	THO complex 1	348	0.92
chr17_35849503_35849741	0.38	DUSP14	dual specificity phosphatase 14	315	0.9
chr11_59523028_59523239	0.38	STX3	syntaxin 3	208	0.82
chr7_65338891_65339374	0.38	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1	776	0.65
chr5_140997244_140997566	0.38	AC008781.7		576	0.53
chr3_72788121_72788360	0.38	ENSG00000222838	.	47278	0.17
chr17_48227691_48228226	0.38	PPP1R9B	protein phosphatase 1, regulatory subunit 9B	81	0.94
chrY_2709555_2710183	0.37	RPS4Y1	ribosomal protein S4, Y-linked 1	92	0.98
chr17_74235938_74236314	0.37	RNF157	ring finger protein 157	256	0.89
chr1_212965305_212965712	0.37	TATDN3	TatD DNase domain containing 3	242	0.64
chr15_63414046_63414224	0.36	LACTB	lactamase, beta	103	0.97
chrX_90690150_90690364	0.36	PABPC5-AS1	PABPC5 antisense RNA 1	259	0.68
chr19_52800063_52800231	0.36	ZNF480	zinc finger protein 480	283	0.77
chr9_43134561_43134712	0.36	AL513478.1	Uncharacterized protein	459	0.7
chr15_29131227_29131499	0.36	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2	54	0.98
chr1_51769559_51769817	0.36	TTC39A	tetratricopeptide repeat domain 39A	6026	0.17
chr9_71737251_71737695	0.36	TJP2	tight junction protein 2	1249	0.57
chr12_49351468_49351675	0.35	ARF3	ADP-ribosylation factor 3	237	0.61
chr17_73285759_73286238	0.35	SLC25A19	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19	407	0.72
chr1_35545080_35545471	0.35	ZMYM1	zinc finger, MYM-type 1	283	0.91
chr20_305267_305844	0.35	RP5-1103G7.4		323	0.68
chr11_134201877_134202251	0.35	GLB1L2	galactosidase, beta 1-like 2	108	0.97
chr9_133538924_133539075	0.35	PRDM12	PR domain containing 12	982	0.58
chr16_67193901_67194322	0.35	TRADD	TNFRSF1A-associated via death domain	90	0.63
chr2_204572665_204572956	0.35	CD28	CD28 molecule	1394	0.52
chr3_39448544_39448796	0.35	RPSA	ribosomal protein SA	444	0.68
chr18_46477183_46477549	0.35	SMAD7	SMAD family member 7	285	0.93
chr15_85113367_85113660	0.35	UBE2Q2P1	ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 1	418	0.57
chr1_28833003_28833253	0.35	RCC1	regulator of chromosome condensation 1	559	0.45
chr1_38510021_38510235	0.34	POU3F1	POU class 3 homeobox 1	2322	0.24
chr4_1107333_1107580	0.34	RP11-20I20.2		29	0.58
chr17_41440194_41440345	0.34	ENSG00000188825	.	24516	0.11
chr17_66959265_66959515	0.34	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8	7898	0.24
chr9_139334453_139334604	0.34	INPP5E	inositol polyphosphate-5-phosphatase, 72 kDa	254	0.85
chr1_155658197_155658425	0.34	YY1AP1	YY1 associated protein 1	45	0.9
chr14_99947789_99947995	0.34	CCNK	cyclin K	130	0.88
chr11_7041299_7041574	0.33	ZNF214	zinc finger protein 214	30	0.76
chr11_82612799_82613018	0.33	C11orf82	chromosome 11 open reading frame 82	124	0.5
chr4_166754962_166755113	0.33	TLL1	tolloid-like 1	39373	0.22
chr8_114446989_114447172	0.33	CSMD3	CUB and Sushi multiple domains 3	2032	0.42
chr19_17136985_17137234	0.33	CPAMD8	C3 and PZP-like, alpha-2-macroglobulin domain containing 8	516	0.7
chr13_100068739_100068890	0.33	ENSG00000266207	.	36909	0.15
chr4_177116463_177116679	0.33	SPATA4	spermatogenesis associated 4	251	0.93
chr7_21985259_21985518	0.33	CDCA7L	cell division cycle associated 7-like	108	0.98
chr11_66725086_66725423	0.33	PC	pyruvate carboxylase	593	0.64
chr2_87798273_87798528	0.33	RP11-1399P15.1		20847	0.27
chr1_249133271_249133538	0.33	ZNF672	zinc finger protein 672	51	0.96
chr15_26095105_26095679	0.33	ENSG00000266517	.	1420	0.42
chr2_136633081_136633631	0.33	MCM6	minichromosome maintenance complex component 6	640	0.71
chr14_100784490_100784674	0.33	ENSG00000243976	.	1125	0.26
chr11_18416232_18416740	0.33	LDHA	lactate dehydrogenase A	235	0.88
chr2_136875892_136876111	0.33	CXCR4	chemokine (C-X-C motif) receptor 4	266	0.95
chr1_116917904_116918072	0.33	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	1499	0.36
chr22_40406174_40406325	0.32	FAM83F	family with sequence similarity 83, member F	557	0.75
chr16_87526842_87527034	0.32	ZCCHC14	zinc finger, CCHC domain containing 14	1287	0.49
chr12_8113260_8113485	0.32	ENSG00000206636	.	15483	0.14
chr8_37605644_37605880	0.32	ERLIN2	ER lipid raft associated 2	10678	0.12
chr11_843458_843641	0.32	TSPAN4	tetraspanin 4	210	0.78
chr19_58898704_58898972	0.32	RPS5	ribosomal protein S5	182	0.75
chr17_38716835_38717173	0.32	CCR7	chemokine (C-C motif) receptor 7	261	0.91
chr1_39499733_39499961	0.31	NDUFS5	NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)	7857	0.18
chr14_74036748_74037002	0.31	ACOT2	acyl-CoA thioesterase 2	1112	0.35
chr6_139094656_139094848	0.31	CCDC28A	coiled-coil domain containing 28A	95	0.97
chr2_241500266_241500461	0.31	ANKMY1	ankyrin repeat and MYND domain containing 1	120	0.87
chr17_14208922_14209145	0.31	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	4633	0.3
chr14_50329070_50329296	0.31	ENSG00000265150	.	384	0.75
chr11_18719924_18720222	0.31	TMEM86A	transmembrane protein 86A	265	0.89
chr2_220094595_220095282	0.31	ANKZF1	ankyrin repeat and zinc finger domain containing 1	257	0.63
chr11_9635266_9635604	0.31	WEE1	WEE1 G2 checkpoint kinase	27174	0.13
chr1_26606672_26606961	0.31	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	203	0.9
chr21_40211978_40212129	0.31	ETS2	v-ets avian erythroblastosis virus E26 oncogene homolog 2	30493	0.21
chr6_37786875_37787134	0.30	RP3-441A12.1		10	0.8
chr17_8089749_8090065	0.30	ENSG00000266638	.	586	0.5
chr16_30968327_30968483	0.30	SETD1A	SET domain containing 1A	210	0.85
chr7_151000467_151000632	0.30	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	25567	0.11
chr10_124134109_124134260	0.30	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	28	0.98
chr18_31158525_31158704	0.30	ASXL3	additional sex combs like 3 (Drosophila)	9	0.99
chr1_2162419_2162570	0.30	SKI	v-ski avian sarcoma viral oncogene homolog	2360	0.2
chr4_82136118_82136337	0.29	PRKG2	protein kinase, cGMP-dependent, type II	9	0.99
chr14_22949288_22949494	0.29	ENSG00000251002	.	887	0.35
chr10_43859218_43859369	0.29	FXYD4	FXYD domain containing ion transport regulator 4	7797	0.17
chr19_13136767_13137028	0.29	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	1086	0.34
chr5_137224846_137225023	0.29	RP11-381K20.2		72	0.67
chr12_864686_864837	0.29	WNK1	WNK lysine deficient protein kinase 1	2029	0.35
chr9_2157815_2158699	0.28	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	199	0.95
chr17_60142459_60142618	0.28	MED13	mediator complex subunit 13	105	0.97
chr3_149531082_149531931	0.28	RNF13	ring finger protein 13	101	0.97
chr20_39311567_39311981	0.28	MAFB	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	5724	0.34
chr16_56709880_56710031	0.28	MT1H	metallothionein 1H	6203	0.08
chr1_154581072_154581232	0.28	ADAR	adenosine deaminase, RNA-specific	470	0.73
chr10_126480570_126481048	0.28	METTL10	methyltransferase like 10	370	0.83
chr11_16759613_16759958	0.28	C11orf58	chromosome 11 open reading frame 58	163	0.97
chr6_144982221_144982372	0.28	UTRN	utrophin	1316	0.63
chr20_47796571_47796722	0.28	STAU1	staufen double-stranded RNA binding protein 1	5846	0.21
chr6_106536140_106536635	0.28	PRDM1	PR domain containing 1, with ZNF domain	932	0.64
chr13_97874593_97875664	0.28	MBNL2	muscleblind-like splicing regulator 2	519	0.87
chr17_81060853_81061004	0.28	METRNL	meteorin, glial cell differentiation regulator-like	8934	0.25
chr9_134152374_134152613	0.28	FAM78A	family with sequence similarity 78, member A	559	0.75
chr10_21822138_21822619	0.27	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	716	0.59
chr5_90677658_90677809	0.27	ARRDC3	arrestin domain containing 3	1443	0.51
chr1_23894723_23894953	0.27	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	8553	0.18
chr8_145980713_145981003	0.27	ZNF251	zinc finger protein 251	32	0.96
chr4_56914817_56915143	0.27	ENSG00000200741	.	48576	0.15
chr16_25123142_25123518	0.27	LCMT1	leucine carboxyl methyltransferase 1	77	0.98
chr5_171434068_171434407	0.27	FBXW11	F-box and WD repeat domain containing 11	360	0.9
chr13_109148449_109148673	0.27	MYO16	myosin XVI	99939	0.08
chr5_68514057_68514286	0.26	MRPS36	mitochondrial ribosomal protein S36	512	0.71
chr8_1772294_1772657	0.26	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10	294	0.91
chr1_155145539_155145727	0.26	KRTCAP2	keratinocyte associated protein 2	176	0.54
chr10_131264926_131265255	0.26	MGMT	O-6-methylguanine-DNA methyltransferase	358	0.9
chr12_32292111_32292535	0.26	RP11-843B15.2		31861	0.19
chr1_15482935_15483201	0.26	TMEM51	transmembrane protein 51	2783	0.3
chr9_35072054_35072271	0.26	VCP	valosin containing protein	151	0.91
chr10_131762270_131762646	0.26	EBF3	early B-cell factor 3	353	0.93
chr15_63449409_63449703	0.26	RPS27L	ribosomal protein S27-like	76	0.97
chr10_126490181_126490332	0.26	FAM175B	family with sequence similarity 175, member B	98	0.96
chr1_156405353_156405868	0.26	C1orf61	chromosome 1 open reading frame 61	6395	0.13
chr1_155532313_155532497	0.26	ASH1L	ash1 (absent, small, or homeotic)-like (Drosophila)	79	0.89
chr14_88459061_88459223	0.26	GALC	galactosylceramidase	40	0.97
chr1_38757878_38758029	0.26	ENSG00000200796	.	104378	0.07
chr7_138916860_138917323	0.26	UBN2	ubinuclein 2	860	0.66
chr5_108745263_108745487	0.26	PJA2	praja ring finger 2, E3 ubiquitin protein ligase	320	0.95
chr12_56522678_56523035	0.26	RP11-603J24.5		218	0.74
chr14_71338943_71339141	0.26	PCNX	pecanex homolog (Drosophila)	35080	0.2
chrX_153084272_153084494	0.26	PDZD4	PDZ domain containing 4	10968	0.09
chr12_2377393_2377544	0.26	CACNA1C-IT3	CACNA1C intronic transcript 3 (non-protein coding)	1474	0.5
chr14_90320573_90320724	0.26	EFCAB11	EF-hand calcium binding domain 11	100219	0.07
chr2_241374046_241374232	0.26	GPC1	glypican 1	949	0.53
chr17_48906674_48906825	0.26	WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	5262	0.17
chr11_61197616_61198048	0.26	SDHAF2	succinate dehydrogenase complex assembly factor 2	216	0.45
chr11_58346016_58346264	0.26	ZFP91	ZFP91 zinc finger protein	444	0.45
chr13_46038649_46038966	0.26	COG3	component of oligomeric golgi complex 3	253	0.93
chr5_134374502_134374924	0.26	PITX1	paired-like homeodomain 1	4210	0.23
chr11_65430663_65431111	0.26	RELA	v-rel avian reticuloendotheliosis viral oncogene homolog A	322	0.76
chr19_12917473_12917666	0.26	RNASEH2A	ribonuclease H2, subunit A	175	0.85
chr6_13486568_13486897	0.25	GFOD1-AS1	GFOD1 antisense RNA 1	206	0.6
chr11_64637981_64638132	0.25	EHD1	EH-domain containing 1	5082	0.11
chr20_34542852_34543053	0.25	SCAND1	SCAN domain containing 1	404	0.81
chr17_74383852_74384098	0.25	SPHK1	sphingosine kinase 1	2602	0.17
chr11_58978519_58978670	0.25	MPEG1	macrophage expressed 1	1830	0.29
chr12_69005315_69005553	0.25	RAP1B	RAP1B, member of RAS oncogene family	629	0.75
chr1_170655624_170655775	0.25	PRRX1	paired related homeobox 1	22621	0.26
chr15_59225515_59225703	0.25	SLTM	SAFB-like, transcription modulator	164	0.95
chr6_24910724_24911222	0.25	FAM65B	family with sequence similarity 65, member B	222	0.95
chr7_855243_855541	0.25	SUN1	Sad1 and UNC84 domain containing 1	136	0.96
chr15_83377850_83378150	0.25	AP3B2	adaptor-related protein complex 3, beta 2 subunit	531	0.69
chr17_17206244_17206395	0.25	NT5M	5',3'-nucleotidase, mitochondrial	330	0.87
chr15_55880849_55881113	0.25	PYGO1	pygopus family PHD finger 1	164	0.97
chr10_13342075_13342296	0.25	PHYH	phytanoyl-CoA 2-hydroxylase	84	0.97
chr2_87883698_87883984	0.25	ENSG00000265507	.	45433	0.18
chr3_195906840_195907022	0.25	ENSG00000222335	.	22289	0.13
chr22_38349726_38350087	0.25	POLR2F	polymerase (RNA) II (DNA directed) polypeptide F	172	0.56
chr22_42486316_42486738	0.25	NDUFA6	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa	256	0.5
chr17_41437916_41438239	0.25	ENSG00000188825	.	26708	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CENPB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	GO:0048520	positive regulation of behavior(GO:0048520)
0.2	0.5	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.6	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.4	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.4	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.1	0.3	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.5	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.3	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1	0.3	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.1	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.2	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1	0.3	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.1	0.3	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.8	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.1	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	0.2	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.1	0.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.1	GO:0071436	sodium ion export(GO:0071436)
0.1	0.2	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.3	GO:0035872	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	0.1	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.1	0.4	GO:0042634	regulation of hair cycle(GO:0042634)
0.1	0.2	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.1	0.2	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.1	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.2	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.2	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.1	0.2	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.4	GO:0045116	protein neddylation(GO:0045116)
0.1	0.2	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.2	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.4	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.3	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.3	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.3	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.3	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0021508	floor plate formation(GO:0021508)
0.0	0.3	GO:0045350	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.2	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.3	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.2	GO:0055026	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.0	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.2	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.6	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.3	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.4	GO:0006862	nucleotide transport(GO:0006862)
0.0	0.1	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.3	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148)
0.0	0.2	GO:1901160	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0	0.0	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.1	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.2	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.3	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.2	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.2	GO:0090399	replicative senescence(GO:0090399)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.2	GO:0008088	axo-dendritic transport(GO:0008088)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.7	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.2	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.0	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.3	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.0	0.2	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0002068	glandular epithelial cell development(GO:0002068)
0.0	0.2	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.9	GO:0042773	ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.5	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.4	GO:0070303	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.2	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.2	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.0	0.0	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.2	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304)
0.0	0.1	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.8	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.0	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.0	GO:0045079	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0042026	protein refolding(GO:0042026)
0.0	0.1	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0033233	regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0	0.2	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.1	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.2	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.1	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.0	GO:0060033	Mullerian duct regression(GO:0001880) anatomical structure regression(GO:0060033)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.3	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.0	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.0	0.0	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0050955	sensory perception of temperature stimulus(GO:0050951) thermoception(GO:0050955)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.0	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.1	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.0	GO:0009437	amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.0	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.3	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.5	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0033081	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.4	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.3	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.0	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	1.0	GO:0006415	translational termination(GO:0006415)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.0	GO:0034390	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.2	GO:0001569	patterning of blood vessels(GO:0001569)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.2	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:1903170	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.2	GO:0006400	tRNA modification(GO:0006400)
0.0	0.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.1	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.4	GO:0006695	cholesterol biosynthetic process(GO:0006695)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.0	GO:0006266	DNA ligation(GO:0006266)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.3	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	1.1	GO:0006184	obsolete GTP catabolic process(GO:0006184)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.3	GO:0070552	BRISC complex(GO:0070552)
0.1	0.3	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.4	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.1	0.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.3	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1	0.3	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.9	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.7	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:0042555	MCM complex(GO:0042555)
0.0	1.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.4	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.3	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.4	GO:0031201	SNARE complex(GO:0031201)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.5	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.7	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.0	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.3	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.0	GO:0043657	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.9	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	1.9	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.0	GO:0043218	compact myelin(GO:0043218)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	1.0	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.7	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.3	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.0	0.0	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.3	GO:0030666	endocytic vesicle membrane(GO:0030666)
0.0	1.4	GO:0005840	ribosome(GO:0005840)
0.0	0.3	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.4	GO:0005814	centriole(GO:0005814)
0.0	0.6	GO:0000786	nucleosome(GO:0000786)
0.0	0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.6	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.1	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.0	GO:0043230	extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.3	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.3	GO:0045159	myosin II binding(GO:0045159)
0.1	0.3	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1	0.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.3	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.3	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.3	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.3	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.5	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.4	GO:0008494	translation activator activity(GO:0008494)
0.1	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.7	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.5	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.6	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.3	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.6	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.6	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.3	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.2	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.6	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.2	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.3	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.7	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.8	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.6	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.2	GO:0043176	amine binding(GO:0043176)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.3	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.2	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.8	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.0	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.5	GO:0046332	SMAD binding(GO:0046332)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.8	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.3	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.3	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0	0.4	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.2	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.0	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.0	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.2	GO:0017069	snRNA binding(GO:0017069)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.7	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.5	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.3	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.0	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.0	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.0	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.0	GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.0	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	1.5	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.7	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.3	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.4	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
1.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
1.0	PID BMP PATHWAY	BMP receptor signaling
0.8	PID FOXO PATHWAY	FoxO family signaling
0.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.6	PID RHOA PATHWAY	RhoA signaling pathway
0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.3	PID BARD1 PATHWAY	BARD1 signaling events
1.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.4	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.3	PID E2F PATHWAY	E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	1.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.4	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	1.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.7	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	1.1	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	1.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.4	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	0.2	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.3	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.7	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.1	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	2.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.8	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand

Results for CENPB

Z-value: 1.80

Motif logo

Transcription factors associated with CENPB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the CENPB motif across conditions

Conditions sorted by the z-value of the CENPB motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CENPB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: