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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for CLOCK

Z-value: 1.40

Motif logo

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Transcription factors associated with CLOCK

Gene Symbol Gene ID Gene Info
CLOCK
ENSG00000134852.10 clock circadian regulator

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_56420027_56420231CLOCK68240.1506290.809.7e-03Click!
chr4_56416241_56416392CLOCK30110.1857050.732.4e-02Click!
chr4_56415825_56415976CLOCK25950.1984960.599.4e-02Click!
chr4_56411449_56411709CLOCK5200.6769210.304.3e-01Click!
chr4_56410409_56410560CLOCK16150.2793930.225.7e-01Click!

Activity of the CLOCK motif across conditions

Conditions sorted by the z-value of the CLOCK motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_2524704_2524855 0.93 ENSG00000252962
 .
 21640
 0.14
chr4_148402515_148403207 0.91 EDNRA
 endothelin receptor type A
 777
 0.76
chr7_15725092_15725754 0.84 MEOX2
 mesenchyme homeobox 2
 1014
 0.63
chr16_2077067_2078193 0.83 SLC9A3R2
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
 701
 0.35
chr11_121593168_121593875 0.78 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 132393
 0.05
chr16_88450130_88450579 0.73 ZNF469
 zinc finger protein 469
 43525
 0.15
chr1_215180647_215181021 0.72 KCNK2
 potassium channel, subfamily K, member 2
 1636
 0.56
chr8_42063953_42065062 0.71 PLAT
 plasminogen activator, tissue
 576
 0.71
chr1_182993880_182994112 0.68 LAMC1
 laminin, gamma 1 (formerly LAMB2)
 1401
 0.44
chr19_54534256_54534469 0.68 VSTM1
 V-set and transmembrane domain containing 1
 27315
 0.08
chr1_218672576_218672996 0.68 C1orf143
 chromosome 1 open reading frame 143
 10652
 0.26
chr19_49661333_49661989 0.67 TRPM4
 transient receptor potential cation channel, subfamily M, member 4
 562
 0.58
chrX_99899594_99899808 0.62 SRPX2
 sushi-repeat containing protein, X-linked 2
 486
 0.79
chr18_53214040_53214242 0.62 TCF4
 transcription factor 4
 36141
 0.18
chr20_19956104_19956326 0.61 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 41545
 0.15
chr9_125108952_125109296 0.60 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
 23700
 0.11
chr1_13910795_13911459 0.60 PDPN
 podoplanin
 362
 0.87
chr22_46480425_46480827 0.57 FLJ27365
 hsa-mir-4763
 1257
 0.28
chr4_114679710_114679861 0.56 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 2439
 0.44
chr10_101088892_101089952 0.56 CNNM1
 cyclin M1
 266
 0.95
chr5_98397075_98397538 0.56 ENSG00000200351
 .
 124855
 0.06
chr10_13748513_13748974 0.55 ENSG00000222235
 .
 1765
 0.25
chr2_218866820_218867225 0.55 TNS1
 tensin 1
 696
 0.69
chr11_63530349_63531105 0.54 ENSG00000264519
 .
 34816
 0.12
chr10_29010987_29011704 0.54 ENSG00000201001
 .
 38387
 0.14
chr8_494269_494491 0.54 TDRP
 testis development related protein
 457
 0.88
chr7_41740779_41741576 0.54 INHBA
 inhibin, beta A
 970
 0.56
chr11_10920623_10921193 0.54 ZBED5-AS1
 ZBED5 antisense RNA 1
 34100
 0.15
chr7_121513797_121514084 0.53 PTPRZ1
 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
 525
 0.87
chr5_98111445_98111873 0.52 RGMB
 repulsive guidance molecule family member b
 2320
 0.3
chr17_65524931_65525141 0.52 CTD-2653B5.1
4439
 0.23
chr20_35489968_35490220 0.52 SOGA1
 suppressor of glucose, autophagy associated 1
 1818
 0.31
chr5_14441548_14441780 0.51 TRIO
 trio Rho guanine nucleotide exchange factor
 46893
 0.19
chr11_119303601_119304219 0.51 THY1
 Thy-1 cell surface antigen
 8215
 0.14
chr10_95239818_95240064 0.51 MYOF
 myoferlin
 2010
 0.32
chr2_79739509_79740065 0.51 CTNNA2
 catenin (cadherin-associated protein), alpha 2
 339
 0.91
chr21_45065665_45065838 0.50 HSF2BP
 heat shock transcription factor 2 binding protein
 12274
 0.2
chr17_29887977_29888214 0.50 ENSG00000207614
 .
 1080
 0.35
chr5_176901024_176901292 0.50 DBN1
 drebrin 1
 244
 0.85
chr4_20252886_20253037 0.50 SLIT2
 slit homolog 2 (Drosophila)
 1922
 0.5
chr20_61817533_61817684 0.49 ENSG00000207598
 .
 7756
 0.14
chr7_129933276_129933885 0.49 CPA4
 carboxypeptidase A4
 461
 0.76
chr2_74606600_74607395 0.48 DCTN1
 dynactin 1
 413
 0.73
chr14_105434639_105435137 0.48 AHNAK2
 AHNAK nucleoprotein 2
 9806
 0.16
chrX_130964358_130965005 0.48 ENSG00000200587
 .
 108303
 0.07
chr2_236401822_236402641 0.48 AGAP1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 502
 0.83
chr4_126311427_126311944 0.47 FAT4
 FAT atypical cadherin 4
 3406
 0.33
chr10_128076215_128076453 0.47 ADAM12
 ADAM metallopeptidase domain 12
 690
 0.79
chr4_95679455_95679870 0.47 BMPR1B
 bone morphogenetic protein receptor, type IB
 543
 0.88
chr6_169653425_169653684 0.47 THBS2
 thrombospondin 2
 585
 0.83
chr19_45655667_45657201 0.46 NKPD1
 NTPase, KAP family P-loop domain containing 1
 594
 0.58
chr12_59311566_59311750 0.46 LRIG3
 leucine-rich repeats and immunoglobulin-like domains 3
 1669
 0.41
chr14_80677438_80677725 0.46 DIO2
 deiodinase, iodothyronine, type II
 76
 0.65
chr1_60031328_60031726 0.46 FGGY
 FGGY carbohydrate kinase domain containing
 11937
 0.3
chr10_131458318_131458596 0.46 RP11-109A6.2
41069
 0.2
chr2_157176521_157176855 0.45 NR4A2
 nuclear receptor subfamily 4, group A, member 2
 9945
 0.27
chr11_12307216_12307605 0.45 MICALCL
 MICAL C-terminal like
 1037
 0.52
chr6_151482130_151482281 0.45 ENSG00000238616
 .
 40271
 0.14
chr11_46299677_46300088 0.45 CREB3L1
 cAMP responsive element binding protein 3-like 1
 654
 0.68
chr6_86170308_86170602 0.45 NT5E
 5'-nucleotidase, ecto (CD73)
 10628
 0.27
chr2_36583449_36584760 0.44 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 490
 0.89
chr18_60092781_60092970 0.44 RP11-640A1.3
47512
 0.14
chr19_39034426_39034595 0.44 AC067969.2
6742
 0.13
chr3_185531595_185531973 0.44 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
 7065
 0.24
chr7_94028286_94028494 0.44 COL1A2
 collagen, type I, alpha 2
 4517
 0.32
chr17_36611061_36611448 0.43 ARHGAP23
 Rho GTPase activating protein 23
 2390
 0.23
chr4_114897314_114897610 0.43 ARSJ
 arylsulfatase family, member J
 2690
 0.37
chr6_56111778_56112295 0.43 COL21A1
 collagen, type XXI, alpha 1
 199
 0.97
chr12_106534242_106534393 0.43 NUAK1
 NUAK family, SNF1-like kinase, 1
 506
 0.84
chr16_69140450_69141374 0.43 HAS3
 hyaluronan synthase 3
 400
 0.81
chr7_150823244_150823438 0.43 AGAP3
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
 8045
 0.11
chr5_172754839_172755250 0.43 STC2
 stanniocalcin 2
 12
 0.98
chr3_33318777_33319866 0.42 FBXL2
 F-box and leucine-rich repeat protein 2
 353
 0.91
chr12_16500618_16501134 0.42 MGST1
 microsomal glutathione S-transferase 1
 145
 0.97
chr8_80524769_80525254 0.41 STMN2
 stathmin-like 2
 1041
 0.69
chr10_114714851_114715858 0.41 RP11-57H14.2
3720
 0.26
chr12_117096711_117096912 0.41 C12orf49
 chromosome 12 open reading frame 49
 61121
 0.12
chr15_96883311_96883827 0.41 ENSG00000222651
 .
 7079
 0.16
chr22_46474135_46474286 0.41 FLJ27365
 hsa-mir-4763
 1982
 0.18
chr7_134466741_134466892 0.41 CALD1
 caldesmon 1
 2387
 0.42
chr15_96875667_96876080 0.41 NR2F2
 nuclear receptor subfamily 2, group F, member 2
 79
 0.9
chr1_95006423_95007262 0.40 F3
 coagulation factor III (thromboplastin, tissue factor)
 351
 0.93
chr4_159090784_159091060 0.40 FAM198B
 family with sequence similarity 198, member B
 608
 0.57
chr4_82134488_82134639 0.40 PRKG2
 protein kinase, cGMP-dependent, type II
 1625
 0.48
chr2_19556916_19557067 0.40 OSR1
 odd-skipped related transciption factor 1
 314
 0.92
chr4_187149514_187149678 0.40 KLKB1
 kallikrein B, plasma (Fletcher factor) 1
 924
 0.55
chr19_10927638_10927909 0.40 ENSG00000207752
 .
 399
 0.76
chr1_3229365_3229516 0.40 PRDM16
 PR domain containing 16
 68744
 0.11
chr20_60941163_60941716 0.39 LAMA5
 laminin, alpha 5
 887
 0.46
chr10_70752640_70752954 0.39 KIAA1279
 KIAA1279
 4310
 0.2
chr8_72274079_72274393 0.39 EYA1
 eyes absent homolog 1 (Drosophila)
 135
 0.98
chr1_162532826_162532977 0.39 UAP1
 UDP-N-acteylglucosamine pyrophosphorylase 1
 1578
 0.3
chr2_238116736_238116905 0.39 AC112715.2
 Uncharacterized protein
 48914
 0.16
chr7_105410385_105410536 0.39 ATXN7L1
 ataxin 7-like 1
 78376
 0.11
chr16_30996962_30997263 0.39 AC135048.1
 Uncharacterized protein
 421
 0.49
chr10_73595617_73595788 0.39 ENSG00000238446
 .
 8849
 0.18
chr21_28213355_28213525 0.39 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 1897
 0.43
chr7_131377016_131377218 0.39 PODXL
 podocalyxin-like
 135741
 0.05
chr20_55207246_55207474 0.39 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
 1422
 0.37
chr4_164086732_164088087 0.39 NAF1
 nuclear assembly factor 1 ribonucleoprotein
 633
 0.81
chr3_36422437_36422689 0.38 STAC
 SH3 and cysteine rich domain
 498
 0.89
chr13_98796700_98796948 0.38 FARP1
 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
 1090
 0.54
chr7_94029074_94029225 0.38 COL1A2
 collagen, type I, alpha 2
 5276
 0.3
chr1_120189851_120190681 0.38 ZNF697
 zinc finger protein 697
 130
 0.97
chr12_10874089_10875353 0.38 YBX3
 Y box binding protein 3
 1185
 0.46
chr1_101313202_101313363 0.38 EXTL2
 exostosin-like glycosyltransferase 2
 46938
 0.12
chr9_130860823_130861938 0.38 SLC25A25
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
 544
 0.57
chr8_77596046_77596230 0.38 ZFHX4
 zinc finger homeobox 4
 122
 0.9
chr10_72433794_72433958 0.38 ADAMTS14
 ADAM metallopeptidase with thrombospondin type 1 motif, 14
 1317
 0.54
chr12_116820769_116821023 0.38 ENSG00000264037
 .
 45227
 0.17
chr2_131792690_131793026 0.37 ARHGEF4
 Rho guanine nucleotide exchange factor (GEF) 4
 5992
 0.24
chr17_77015960_77016131 0.37 C1QTNF1
 C1q and tumor necrosis factor related protein 1
 2851
 0.19
chr10_103542090_103543195 0.37 NPM3
 nucleophosmin/nucleoplasmin 3
 528
 0.73
chr14_42075070_42075221 0.37 LRFN5
 leucine rich repeat and fibronectin type III domain containing 5
 1628
 0.47
chr4_41205170_41205321 0.37 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 11230
 0.21
chr3_98616068_98616219 0.37 DCBLD2
 discoidin, CUB and LCCL domain containing 2
 3872
 0.21
chr12_124872056_124872210 0.37 NCOR2
 nuclear receptor corepressor 2
 1237
 0.6
chr5_121648745_121649192 0.37 SNCAIP
 synuclein, alpha interacting protein
 706
 0.63
chr15_92104669_92104931 0.37 ENSG00000238981
 .
 273809
 0.01
chr2_241376186_241376470 0.37 GPC1
 glypican 1
 1240
 0.43
chr21_43343811_43344157 0.37 C2CD2
 C2 calcium-dependent domain containing 2
 2815
 0.23
chr2_227665986_227666395 0.37 IRS1
 insulin receptor substrate 1
 1715
 0.35
chr12_105093403_105093554 0.37 ENSG00000264295
 .
 108067
 0.06
chr5_15620667_15620944 0.37 FBXL7
 F-box and leucine-rich repeat protein 7
 4714
 0.28
chr1_32166216_32166367 0.37 COL16A1
 collagen, type XVI, alpha 1
 3477
 0.18
chr13_36273248_36273465 0.37 NBEA
 neurobeachin
 106213
 0.07
chr15_40631891_40632187 0.37 C15orf52
 chromosome 15 open reading frame 52
 204
 0.85
chr4_183066743_183066954 0.37 AC108142.1
446
 0.58
chr7_116072829_116072980 0.36 ENSG00000252672
 .
 364
 0.88
chr2_190042728_190042905 0.36 COL5A2
 collagen, type V, alpha 2
 1789
 0.42
chr12_113654987_113655138 0.36 IQCD
 IQ motif containing D
 3770
 0.14
chr15_51202438_51202589 0.36 AP4E1
 adaptor-related protein complex 4, epsilon 1 subunit
 1521
 0.52
chr13_114065375_114065695 0.36 ADPRHL1
 ADP-ribosylhydrolase like 1
 37922
 0.11
chr8_13423939_13424235 0.36 C8orf48
 chromosome 8 open reading frame 48
 265
 0.93
chr4_147143374_147143555 0.36 RP11-6L6.2
 Uncharacterized protein
 2245
 0.33
chr9_130330127_130331202 0.36 FAM129B
 family with sequence similarity 129, member B
 703
 0.67
chr17_4457746_4458738 0.36 MYBBP1A
 MYB binding protein (P160) 1a
 35
 0.96
chr1_163039219_163039545 0.36 RGS4
 regulator of G-protein signaling 4
 231
 0.96
chr1_182992978_182993852 0.36 LAMC1
 laminin, gamma 1 (formerly LAMB2)
 820
 0.64
chr16_11422925_11423155 0.36 RMI2
 RecQ mediated genome instability 2
 12404
 0.08
chr5_32714055_32714206 0.36 NPR3
 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
 1693
 0.46
chr3_194089318_194089469 0.35 LRRC15
 leucine rich repeat containing 15
 1067
 0.5
chr9_132514889_132515259 0.35 PTGES
 prostaglandin E synthase
 252
 0.91
chr11_65203008_65203266 0.35 ENSG00000245532
 .
 8792
 0.12
chr2_158113918_158114875 0.35 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
 286
 0.93
chr2_62806474_62806625 0.35 TMEM17
 transmembrane protein 17
 73073
 0.1
chr13_24006860_24007105 0.35 SACS
 spastic ataxia of Charlevoix-Saguenay (sacsin)
 859
 0.74
chr19_39465746_39466043 0.35 FBXO17
 F-box protein 17
 656
 0.55
chr7_29605545_29606286 0.35 PRR15
 proline rich 15
 849
 0.6
chr5_83018371_83018587 0.35 HAPLN1
 hyaluronan and proteoglycan link protein 1
 1047
 0.55
chr2_134457926_134458077 0.35 ENSG00000200708
 .
 104339
 0.08
chr3_134516021_134516172 0.35 EPHB1
 EPH receptor B1
 1113
 0.53
chr21_17490330_17490719 0.35 ENSG00000252273
 .
 82695
 0.11
chr4_73433751_73434036 0.35 ADAMTS3
 ADAM metallopeptidase with thrombospondin type 1 motif, 3
 623
 0.85
chr16_19125601_19126223 0.34 ITPRIPL2
 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
 658
 0.65
chr9_133656541_133656767 0.34 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 53799
 0.13
chr6_110720825_110721164 0.34 DDO
 D-aspartate oxidase
 15771
 0.18
chr2_235862821_235863118 0.34 SH3BP4
 SH3-domain binding protein 4
 2249
 0.48
chr7_116166933_116167162 0.34 CAV1
 caveolin 1, caveolae protein, 22kDa
 700
 0.64
chr3_29365630_29365959 0.34 RBMS3-AS3
 RBMS3 antisense RNA 3
 33577
 0.18
chr20_4953796_4953984 0.34 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
 28255
 0.16
chr10_42971061_42971275 0.34 CCNYL2
 cyclin Y-like 2
 21006
 0.25
chr12_2162948_2163118 0.34 CACNA1C
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 304
 0.88
chr21_17569279_17569619 0.34 ENSG00000201025
 .
 87640
 0.1
chr1_215179577_215179737 0.34 KCNK2
 potassium channel, subfamily K, member 2
 459
 0.91
chr12_59313444_59313663 0.34 LRIG3
 leucine-rich repeats and immunoglobulin-like domains 3
 226
 0.87
chr7_42896384_42896593 0.34 C7orf25
 chromosome 7 open reading frame 25
 55021
 0.14
chr13_36921048_36921199 0.34 SPG20
 spastic paraplegia 20 (Troyer syndrome)
 189
 0.8
chr15_100651358_100651509 0.34 ADAMTS17
 ADAM metallopeptidase with thrombospondin type 1 motif, 17
 2121
 0.32
chr9_18976648_18977105 0.33 FAM154A
 family with sequence similarity 154, member A
 56310
 0.1
chr13_113870666_113870964 0.33 CUL4A
 cullin 4A
 6957
 0.15
chr5_155109546_155109697 0.33 ENSG00000200275
 .
 162826
 0.04
chr16_51187585_51187736 0.33 SALL1
 spalt-like transcription factor 1
 2474
 0.33
chr6_68339473_68339624 0.33 ENSG00000206672
 .
 4299
 0.34
chr5_141633749_141633900 0.33 SPRY4
 sprouty homolog 4 (Drosophila)
 69923
 0.11
chr1_156051080_156051411 0.33 MEX3A
 mex-3 RNA binding family member A
 544
 0.52
chr5_67629922_67630135 0.33 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 41632
 0.21
chr14_86000741_86001075 0.33 FLRT2
 fibronectin leucine rich transmembrane protein 2
 4336
 0.28
chr19_7953693_7954073 0.33 LRRC8E
 leucine rich repeat containing 8 family, member E
 447
 0.57
chr7_807627_807778 0.33 HEATR2
 HEAT repeat containing 2
 410
 0.85
chr7_73705038_73705189 0.33 CLIP2
 CAP-GLY domain containing linker protein 2
 1308
 0.44
chr8_122653917_122654172 0.33 HAS2-AS1
 HAS2 antisense RNA 1
 368
 0.53
chr19_47523477_47523748 0.33 NPAS1
 neuronal PAS domain protein 1
 506
 0.76
chr18_31158744_31159369 0.33 ASXL3
 additional sex combs like 3 (Drosophila)
 426
 0.91
chr16_11454825_11454976 0.33 RP11-485G7.6
11722
 0.09
chr15_73979338_73979524 0.33 CD276
 CD276 molecule
 2084
 0.37
chr10_114718428_114718838 0.33 RP11-57H14.2
6999
 0.23
chr4_123749443_123749605 0.32 ENSG00000253069
 .
 1355
 0.35
chr15_37878826_37879013 0.32 TMCO5A
 transmembrane and coiled-coil domains 5A
 335221
 0.01
chr11_69455246_69455451 0.32 CCND1
 cyclin D1
 507
 0.82
chr4_17783154_17783359 0.32 FAM184B
 family with sequence similarity 184, member B
 121
 0.97
chr6_167764253_167765165 0.32 TTLL2
 tubulin tyrosine ligase-like family, member 2
 26135
 0.18
chr10_91294704_91295240 0.32 SLC16A12
 solute carrier family 16, member 12
 341
 0.89
chr2_199237110_199237329 0.32 ENSG00000252511
 .
 194234
 0.03
chr1_33366734_33367013 0.32 TMEM54
 transmembrane protein 54
 86
 0.96
chr4_25101011_25101194 0.32 SEPSECS
 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
 60918
 0.11
chr12_91775039_91775202 0.32 DCN
 decorin
 198220
 0.03
chr22_27152907_27153066 0.32 CRYBA4
 crystallin, beta A4
 135058
 0.05
chr17_80339190_80339423 0.32 UTS2R
 urotensin 2 receptor
 7153
 0.1
chr11_58673339_58673578 0.32 AP001652.1
 Uncharacterized protein; cDNA FLJ60524
 561
 0.71

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of CLOCK

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.6 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.2 0.8 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.2 0.5 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.2 0.5 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.2 0.5 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.2 0.5 GO:0031223 auditory behavior(GO:0031223)
0.1 0.6 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.9 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1 0.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.4 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.3 GO:1903332 regulation of protein folding(GO:1903332)
0.1 0.5 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.5 GO:0001757 somite specification(GO:0001757)
0.1 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.6 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.7 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.4 GO:0070141 response to UV-A(GO:0070141)
0.1 0.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.2 GO:0060536 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1 0.2 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.1 0.2 GO:0060676 ureteric bud formation(GO:0060676)
0.1 0.5 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.3 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.1 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1 0.3 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.1 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.2 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.1 GO:0043096 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.7 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 0.2 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.1 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.3 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1 0.2 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.1 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.2 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.1 0.2 GO:2000095 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.2 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.1 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.1 0.1 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.6 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:1904936 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0061430 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.2 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0048263 determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.2 GO:0045217 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.0 GO:0010757 regulation of plasminogen activation(GO:0010755) negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.0 GO:0060534 trachea cartilage development(GO:0060534)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0050942 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0010611 regulation of cardiac muscle hypertrophy(GO:0010611)
0.0 0.2 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.1 GO:0060008 Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0 0.0 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.2 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0042520 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0 0.0 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0071398 cellular response to fatty acid(GO:0071398)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.5 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0061162 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.1 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) vein smooth muscle contraction(GO:0014826) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.0 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:1902019 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0061140 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510) lung secretory cell differentiation(GO:0061140)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.2 GO:0019098 reproductive behavior(GO:0019098)
0.0 0.2 GO:0051875 pigment granule localization(GO:0051875)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0061515 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.1 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.0 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.0 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.0 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.1 GO:0071295 cellular response to vitamin(GO:0071295)
0.0 0.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0030540 female genitalia development(GO:0030540)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.2 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.0 GO:1901796 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 0.0 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:0071800 podosome assembly(GO:0071800)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.1 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.1 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.0 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0070852 cell body fiber(GO:0070852)
0.1 0.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.1 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.7 GO:0030315 T-tubule(GO:0030315)
0.1 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.6 GO:0043205 fibril(GO:0043205)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.3 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 4.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.5 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.6 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.3 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0004470 malic enzyme activity(GO:0004470)
0.1 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.5 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1 0.5 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.3 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.0 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.5 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 1.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.2 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.0 GO:0032052 bile acid binding(GO:0032052)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0002060 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.0 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane