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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CLOCK

Z-value: 1.40

Motif logo

Transcription factors associated with CLOCK

Gene Symbol	Gene ID	Gene Info
CLOCK Ensembl NCBI GeneCards UniProt	ENSG00000134852.10	CLOCK

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
CLOCK	chr4_56420027_56420231	6824	0.150629	0.80	9.7e-03	Click!
CLOCK	chr4_56416241_56416392	3011	0.185705	0.73	2.4e-02	Click!
CLOCK	chr4_56415825_56415976	2595	0.198496	0.59	9.4e-02	Click!
CLOCK	chr4_56411449_56411709	520	0.676921	0.30	4.3e-01	Click!
CLOCK	chr4_56410409_56410560	1615	0.279393	0.22	5.7e-01	Click!

Activity of the CLOCK motif across conditions

Conditions sorted by the z-value of the CLOCK motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_2524704_2524855	0.93	ENSG00000252962	.	21640	0.14
chr4_148402515_148403207	0.91	EDNRA	endothelin receptor type A	777	0.76
chr7_15725092_15725754	0.84	MEOX2	mesenchyme homeobox 2	1014	0.63
chr16_2077067_2078193	0.83	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	701	0.35
chr11_121593168_121593875	0.78	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	132393	0.05
chr16_88450130_88450579	0.73	ZNF469	zinc finger protein 469	43525	0.15
chr1_215180647_215181021	0.72	KCNK2	potassium channel, subfamily K, member 2	1636	0.56
chr8_42063953_42065062	0.71	PLAT	plasminogen activator, tissue	576	0.71
chr1_182993880_182994112	0.68	LAMC1	laminin, gamma 1 (formerly LAMB2)	1401	0.44
chr19_54534256_54534469	0.68	VSTM1	V-set and transmembrane domain containing 1	27315	0.08
chr1_218672576_218672996	0.68	C1orf143	chromosome 1 open reading frame 143	10652	0.26
chr19_49661333_49661989	0.67	TRPM4	transient receptor potential cation channel, subfamily M, member 4	562	0.58
chrX_99899594_99899808	0.62	SRPX2	sushi-repeat containing protein, X-linked 2	486	0.79
chr18_53214040_53214242	0.62	TCF4	transcription factor 4	36141	0.18
chr20_19956104_19956326	0.61	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	41545	0.15
chr9_125108952_125109296	0.60	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	23700	0.11
chr1_13910795_13911459	0.60	PDPN	podoplanin	362	0.87
chr22_46480425_46480827	0.57	FLJ27365	hsa-mir-4763	1257	0.28
chr4_114679710_114679861	0.56	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	2439	0.44
chr10_101088892_101089952	0.56	CNNM1	cyclin M1	266	0.95
chr5_98397075_98397538	0.56	ENSG00000200351	.	124855	0.06
chr10_13748513_13748974	0.55	ENSG00000222235	.	1765	0.25
chr2_218866820_218867225	0.55	TNS1	tensin 1	696	0.69
chr11_63530349_63531105	0.54	ENSG00000264519	.	34816	0.12
chr10_29010987_29011704	0.54	ENSG00000201001	.	38387	0.14
chr8_494269_494491	0.54	TDRP	testis development related protein	457	0.88
chr7_41740779_41741576	0.54	INHBA	inhibin, beta A	970	0.56
chr11_10920623_10921193	0.54	ZBED5-AS1	ZBED5 antisense RNA 1	34100	0.15
chr7_121513797_121514084	0.53	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	525	0.87
chr5_98111445_98111873	0.52	RGMB	repulsive guidance molecule family member b	2320	0.3
chr17_65524931_65525141	0.52	CTD-2653B5.1		4439	0.23
chr20_35489968_35490220	0.52	SOGA1	suppressor of glucose, autophagy associated 1	1818	0.31
chr5_14441548_14441780	0.51	TRIO	trio Rho guanine nucleotide exchange factor	46893	0.19
chr11_119303601_119304219	0.51	THY1	Thy-1 cell surface antigen	8215	0.14
chr10_95239818_95240064	0.51	MYOF	myoferlin	2010	0.32
chr2_79739509_79740065	0.51	CTNNA2	catenin (cadherin-associated protein), alpha 2	339	0.91
chr21_45065665_45065838	0.50	HSF2BP	heat shock transcription factor 2 binding protein	12274	0.2
chr17_29887977_29888214	0.50	ENSG00000207614	.	1080	0.35
chr5_176901024_176901292	0.50	DBN1	drebrin 1	244	0.85
chr4_20252886_20253037	0.50	SLIT2	slit homolog 2 (Drosophila)	1922	0.5
chr20_61817533_61817684	0.49	ENSG00000207598	.	7756	0.14
chr7_129933276_129933885	0.49	CPA4	carboxypeptidase A4	461	0.76
chr2_74606600_74607395	0.48	DCTN1	dynactin 1	413	0.73
chr14_105434639_105435137	0.48	AHNAK2	AHNAK nucleoprotein 2	9806	0.16
chrX_130964358_130965005	0.48	ENSG00000200587	.	108303	0.07
chr2_236401822_236402641	0.48	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	502	0.83
chr4_126311427_126311944	0.47	FAT4	FAT atypical cadherin 4	3406	0.33
chr10_128076215_128076453	0.47	ADAM12	ADAM metallopeptidase domain 12	690	0.79
chr4_95679455_95679870	0.47	BMPR1B	bone morphogenetic protein receptor, type IB	543	0.88
chr6_169653425_169653684	0.47	THBS2	thrombospondin 2	585	0.83
chr19_45655667_45657201	0.46	NKPD1	NTPase, KAP family P-loop domain containing 1	594	0.58
chr12_59311566_59311750	0.46	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	1669	0.41
chr14_80677438_80677725	0.46	DIO2	deiodinase, iodothyronine, type II	76	0.65
chr1_60031328_60031726	0.46	FGGY	FGGY carbohydrate kinase domain containing	11937	0.3
chr10_131458318_131458596	0.46	RP11-109A6.2		41069	0.2
chr2_157176521_157176855	0.45	NR4A2	nuclear receptor subfamily 4, group A, member 2	9945	0.27
chr11_12307216_12307605	0.45	MICALCL	MICAL C-terminal like	1037	0.52
chr6_151482130_151482281	0.45	ENSG00000238616	.	40271	0.14
chr11_46299677_46300088	0.45	CREB3L1	cAMP responsive element binding protein 3-like 1	654	0.68
chr6_86170308_86170602	0.45	NT5E	5'-nucleotidase, ecto (CD73)	10628	0.27
chr2_36583449_36584760	0.44	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	490	0.89
chr18_60092781_60092970	0.44	RP11-640A1.3		47512	0.14
chr19_39034426_39034595	0.44	AC067969.2		6742	0.13
chr3_185531595_185531973	0.44	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	7065	0.24
chr7_94028286_94028494	0.44	COL1A2	collagen, type I, alpha 2	4517	0.32
chr17_36611061_36611448	0.43	ARHGAP23	Rho GTPase activating protein 23	2390	0.23
chr4_114897314_114897610	0.43	ARSJ	arylsulfatase family, member J	2690	0.37
chr6_56111778_56112295	0.43	COL21A1	collagen, type XXI, alpha 1	199	0.97
chr12_106534242_106534393	0.43	NUAK1	NUAK family, SNF1-like kinase, 1	506	0.84
chr16_69140450_69141374	0.43	HAS3	hyaluronan synthase 3	400	0.81
chr7_150823244_150823438	0.43	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	8045	0.11
chr5_172754839_172755250	0.43	STC2	stanniocalcin 2	12	0.98
chr3_33318777_33319866	0.42	FBXL2	F-box and leucine-rich repeat protein 2	353	0.91
chr12_16500618_16501134	0.42	MGST1	microsomal glutathione S-transferase 1	145	0.97
chr8_80524769_80525254	0.41	STMN2	stathmin-like 2	1041	0.69
chr10_114714851_114715858	0.41	RP11-57H14.2		3720	0.26
chr12_117096711_117096912	0.41	C12orf49	chromosome 12 open reading frame 49	61121	0.12
chr15_96883311_96883827	0.41	ENSG00000222651	.	7079	0.16
chr22_46474135_46474286	0.41	FLJ27365	hsa-mir-4763	1982	0.18
chr7_134466741_134466892	0.41	CALD1	caldesmon 1	2387	0.42
chr15_96875667_96876080	0.41	NR2F2	nuclear receptor subfamily 2, group F, member 2	79	0.9
chr1_95006423_95007262	0.40	F3	coagulation factor III (thromboplastin, tissue factor)	351	0.93
chr4_159090784_159091060	0.40	FAM198B	family with sequence similarity 198, member B	608	0.57
chr4_82134488_82134639	0.40	PRKG2	protein kinase, cGMP-dependent, type II	1625	0.48
chr2_19556916_19557067	0.40	OSR1	odd-skipped related transciption factor 1	314	0.92
chr4_187149514_187149678	0.40	KLKB1	kallikrein B, plasma (Fletcher factor) 1	924	0.55
chr19_10927638_10927909	0.40	ENSG00000207752	.	399	0.76
chr1_3229365_3229516	0.40	PRDM16	PR domain containing 16	68744	0.11
chr20_60941163_60941716	0.39	LAMA5	laminin, alpha 5	887	0.46
chr10_70752640_70752954	0.39	KIAA1279	KIAA1279	4310	0.2
chr8_72274079_72274393	0.39	EYA1	eyes absent homolog 1 (Drosophila)	135	0.98
chr1_162532826_162532977	0.39	UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1	1578	0.3
chr2_238116736_238116905	0.39	AC112715.2	Uncharacterized protein	48914	0.16
chr7_105410385_105410536	0.39	ATXN7L1	ataxin 7-like 1	78376	0.11
chr16_30996962_30997263	0.39	AC135048.1	Uncharacterized protein	421	0.49
chr10_73595617_73595788	0.39	ENSG00000238446	.	8849	0.18
chr21_28213355_28213525	0.39	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	1897	0.43
chr7_131377016_131377218	0.39	PODXL	podocalyxin-like	135741	0.05
chr20_55207246_55207474	0.39	TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	1422	0.37
chr4_164086732_164088087	0.39	NAF1	nuclear assembly factor 1 ribonucleoprotein	633	0.81
chr3_36422437_36422689	0.38	STAC	SH3 and cysteine rich domain	498	0.89
chr13_98796700_98796948	0.38	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	1090	0.54
chr7_94029074_94029225	0.38	COL1A2	collagen, type I, alpha 2	5276	0.3
chr1_120189851_120190681	0.38	ZNF697	zinc finger protein 697	130	0.97
chr12_10874089_10875353	0.38	YBX3	Y box binding protein 3	1185	0.46
chr1_101313202_101313363	0.38	EXTL2	exostosin-like glycosyltransferase 2	46938	0.12
chr9_130860823_130861938	0.38	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	544	0.57
chr8_77596046_77596230	0.38	ZFHX4	zinc finger homeobox 4	122	0.9
chr10_72433794_72433958	0.38	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif, 14	1317	0.54
chr12_116820769_116821023	0.38	ENSG00000264037	.	45227	0.17
chr2_131792690_131793026	0.37	ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	5992	0.24
chr17_77015960_77016131	0.37	C1QTNF1	C1q and tumor necrosis factor related protein 1	2851	0.19
chr10_103542090_103543195	0.37	NPM3	nucleophosmin/nucleoplasmin 3	528	0.73
chr14_42075070_42075221	0.37	LRFN5	leucine rich repeat and fibronectin type III domain containing 5	1628	0.47
chr4_41205170_41205321	0.37	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	11230	0.21
chr3_98616068_98616219	0.37	DCBLD2	discoidin, CUB and LCCL domain containing 2	3872	0.21
chr12_124872056_124872210	0.37	NCOR2	nuclear receptor corepressor 2	1237	0.6
chr5_121648745_121649192	0.37	SNCAIP	synuclein, alpha interacting protein	706	0.63
chr15_92104669_92104931	0.37	ENSG00000238981	.	273809	0.01
chr2_241376186_241376470	0.37	GPC1	glypican 1	1240	0.43
chr21_43343811_43344157	0.37	C2CD2	C2 calcium-dependent domain containing 2	2815	0.23
chr2_227665986_227666395	0.37	IRS1	insulin receptor substrate 1	1715	0.35
chr12_105093403_105093554	0.37	ENSG00000264295	.	108067	0.06
chr5_15620667_15620944	0.37	FBXL7	F-box and leucine-rich repeat protein 7	4714	0.28
chr1_32166216_32166367	0.37	COL16A1	collagen, type XVI, alpha 1	3477	0.18
chr13_36273248_36273465	0.37	NBEA	neurobeachin	106213	0.07
chr15_40631891_40632187	0.37	C15orf52	chromosome 15 open reading frame 52	204	0.85
chr4_183066743_183066954	0.37	AC108142.1		446	0.58
chr7_116072829_116072980	0.36	ENSG00000252672	.	364	0.88
chr2_190042728_190042905	0.36	COL5A2	collagen, type V, alpha 2	1789	0.42
chr12_113654987_113655138	0.36	IQCD	IQ motif containing D	3770	0.14
chr15_51202438_51202589	0.36	AP4E1	adaptor-related protein complex 4, epsilon 1 subunit	1521	0.52
chr13_114065375_114065695	0.36	ADPRHL1	ADP-ribosylhydrolase like 1	37922	0.11
chr8_13423939_13424235	0.36	C8orf48	chromosome 8 open reading frame 48	265	0.93
chr4_147143374_147143555	0.36	RP11-6L6.2	Uncharacterized protein	2245	0.33
chr9_130330127_130331202	0.36	FAM129B	family with sequence similarity 129, member B	703	0.67
chr17_4457746_4458738	0.36	MYBBP1A	MYB binding protein (P160) 1a	35	0.96
chr1_163039219_163039545	0.36	RGS4	regulator of G-protein signaling 4	231	0.96
chr1_182992978_182993852	0.36	LAMC1	laminin, gamma 1 (formerly LAMB2)	820	0.64
chr16_11422925_11423155	0.36	RMI2	RecQ mediated genome instability 2	12404	0.08
chr5_32714055_32714206	0.36	NPR3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	1693	0.46
chr3_194089318_194089469	0.35	LRRC15	leucine rich repeat containing 15	1067	0.5
chr9_132514889_132515259	0.35	PTGES	prostaglandin E synthase	252	0.91
chr11_65203008_65203266	0.35	ENSG00000245532	.	8792	0.12
chr2_158113918_158114875	0.35	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	286	0.93
chr2_62806474_62806625	0.35	TMEM17	transmembrane protein 17	73073	0.1
chr13_24006860_24007105	0.35	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	859	0.74
chr19_39465746_39466043	0.35	FBXO17	F-box protein 17	656	0.55
chr7_29605545_29606286	0.35	PRR15	proline rich 15	849	0.6
chr5_83018371_83018587	0.35	HAPLN1	hyaluronan and proteoglycan link protein 1	1047	0.55
chr2_134457926_134458077	0.35	ENSG00000200708	.	104339	0.08
chr3_134516021_134516172	0.35	EPHB1	EPH receptor B1	1113	0.53
chr21_17490330_17490719	0.35	ENSG00000252273	.	82695	0.11
chr4_73433751_73434036	0.35	ADAMTS3	ADAM metallopeptidase with thrombospondin type 1 motif, 3	623	0.85
chr16_19125601_19126223	0.34	ITPRIPL2	inositol 1,4,5-trisphosphate receptor interacting protein-like 2	658	0.65
chr9_133656541_133656767	0.34	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	53799	0.13
chr6_110720825_110721164	0.34	DDO	D-aspartate oxidase	15771	0.18
chr2_235862821_235863118	0.34	SH3BP4	SH3-domain binding protein 4	2249	0.48
chr7_116166933_116167162	0.34	CAV1	caveolin 1, caveolae protein, 22kDa	700	0.64
chr3_29365630_29365959	0.34	RBMS3-AS3	RBMS3 antisense RNA 3	33577	0.18
chr20_4953796_4953984	0.34	SLC23A2	solute carrier family 23 (ascorbic acid transporter), member 2	28255	0.16
chr10_42971061_42971275	0.34	CCNYL2	cyclin Y-like 2	21006	0.25
chr12_2162948_2163118	0.34	CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	304	0.88
chr21_17569279_17569619	0.34	ENSG00000201025	.	87640	0.1
chr1_215179577_215179737	0.34	KCNK2	potassium channel, subfamily K, member 2	459	0.91
chr12_59313444_59313663	0.34	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	226	0.87
chr7_42896384_42896593	0.34	C7orf25	chromosome 7 open reading frame 25	55021	0.14
chr13_36921048_36921199	0.34	SPG20	spastic paraplegia 20 (Troyer syndrome)	189	0.8
chr15_100651358_100651509	0.34	ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	2121	0.32
chr9_18976648_18977105	0.33	FAM154A	family with sequence similarity 154, member A	56310	0.1
chr13_113870666_113870964	0.33	CUL4A	cullin 4A	6957	0.15
chr5_155109546_155109697	0.33	ENSG00000200275	.	162826	0.04
chr16_51187585_51187736	0.33	SALL1	spalt-like transcription factor 1	2474	0.33
chr6_68339473_68339624	0.33	ENSG00000206672	.	4299	0.34
chr5_141633749_141633900	0.33	SPRY4	sprouty homolog 4 (Drosophila)	69923	0.11
chr1_156051080_156051411	0.33	MEX3A	mex-3 RNA binding family member A	544	0.52
chr5_67629922_67630135	0.33	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	41632	0.21
chr14_86000741_86001075	0.33	FLRT2	fibronectin leucine rich transmembrane protein 2	4336	0.28
chr19_7953693_7954073	0.33	LRRC8E	leucine rich repeat containing 8 family, member E	447	0.57
chr7_807627_807778	0.33	HEATR2	HEAT repeat containing 2	410	0.85
chr7_73705038_73705189	0.33	CLIP2	CAP-GLY domain containing linker protein 2	1308	0.44
chr8_122653917_122654172	0.33	HAS2-AS1	HAS2 antisense RNA 1	368	0.53
chr19_47523477_47523748	0.33	NPAS1	neuronal PAS domain protein 1	506	0.76
chr18_31158744_31159369	0.33	ASXL3	additional sex combs like 3 (Drosophila)	426	0.91
chr16_11454825_11454976	0.33	RP11-485G7.6		11722	0.09
chr15_73979338_73979524	0.33	CD276	CD276 molecule	2084	0.37
chr10_114718428_114718838	0.33	RP11-57H14.2		6999	0.23
chr4_123749443_123749605	0.32	ENSG00000253069	.	1355	0.35
chr15_37878826_37879013	0.32	TMCO5A	transmembrane and coiled-coil domains 5A	335221	0.01
chr11_69455246_69455451	0.32	CCND1	cyclin D1	507	0.82
chr4_17783154_17783359	0.32	FAM184B	family with sequence similarity 184, member B	121	0.97
chr6_167764253_167765165	0.32	TTLL2	tubulin tyrosine ligase-like family, member 2	26135	0.18
chr10_91294704_91295240	0.32	SLC16A12	solute carrier family 16, member 12	341	0.89
chr2_199237110_199237329	0.32	ENSG00000252511	.	194234	0.03
chr1_33366734_33367013	0.32	TMEM54	transmembrane protein 54	86	0.96
chr4_25101011_25101194	0.32	SEPSECS	Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase	60918	0.11
chr12_91775039_91775202	0.32	DCN	decorin	198220	0.03
chr22_27152907_27153066	0.32	CRYBA4	crystallin, beta A4	135058	0.05
chr17_80339190_80339423	0.32	UTS2R	urotensin 2 receptor	7153	0.1
chr11_58673339_58673578	0.32	AP001652.1	Uncharacterized protein; cDNA FLJ60524	561	0.71

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CLOCK

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.2	0.6	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2	0.6	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.2	0.8	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.2	0.5	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.2	0.5	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.2	0.5	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.2	0.5	GO:0031223	auditory behavior(GO:0031223)
0.1	0.6	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.9	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1	0.4	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.1	0.4	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.3	GO:1903332	regulation of protein folding(GO:1903332)
0.1	0.5	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.5	GO:0001757	somite specification(GO:0001757)
0.1	0.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.6	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.4	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.1	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.7	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.4	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.1	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.4	GO:0070141	response to UV-A(GO:0070141)
0.1	0.3	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.3	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.2	GO:0060536	trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1	0.2	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.2	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.2	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.5	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.3	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.1	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.3	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.4	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.2	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.1	GO:0043096	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.7	GO:0042474	middle ear morphogenesis(GO:0042474)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1	0.2	GO:0034629	cellular protein complex localization(GO:0034629)
0.1	0.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.2	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.2	GO:0016199	axon midline choice point recognition(GO:0016199)
0.1	0.3	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1	0.2	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.1	0.2	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.2	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.1	0.2	GO:2000095	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.2	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.1	1.1	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.2	GO:0051503	adenine nucleotide transport(GO:0051503)
0.1	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.2	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.3	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.1	0.1	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.1	0.1	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.1	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.6	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.6	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:1904936	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.2	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0090267	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.3	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.3	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.0	0.3	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.2	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0048263	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.7	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.2	GO:0045217	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0010757	regulation of plasminogen activation(GO:0010755) negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.4	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.4	GO:0046697	decidualization(GO:0046697)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.3	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.1	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0060534	trachea cartilage development(GO:0060534)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.5	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.2	GO:0090399	replicative senescence(GO:0090399)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.6	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0050942	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.4	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.2	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0010611	regulation of cardiac muscle hypertrophy(GO:0010611)
0.0	0.2	GO:0002209	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0	0.1	GO:0060008	Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0	0.0	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.2	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.2	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0042520	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.0	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0071398	cellular response to fatty acid(GO:0071398)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.5	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0061162	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.0	GO:0001865	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.0	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) vein smooth muscle contraction(GO:0014826) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.0	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:1902019	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.2	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.3	GO:0002088	lens development in camera-type eye(GO:0002088)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0061140	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510) lung secretory cell differentiation(GO:0061140)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.2	GO:0019098	reproductive behavior(GO:0019098)
0.0	0.2	GO:0051875	pigment granule localization(GO:0051875)
0.0	0.1	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.1	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.1	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.0	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0060033	anatomical structure regression(GO:0060033)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0071295	cellular response to vitamin(GO:0071295)
0.0	0.0	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.1	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0030540	female genitalia development(GO:0030540)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.2	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.0	GO:1901796	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) regulation of signal transduction by p53 class mediator(GO:1901796)
0.0	0.0	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.1	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.0	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0002320	lymphoid progenitor cell differentiation(GO:0002320)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.1	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.0	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.0	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.2	GO:0008206	bile acid metabolic process(GO:0008206)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.4	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.4	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.3	GO:0070852	cell body fiber(GO:0070852)
0.1	0.6	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.7	GO:0030315	T-tubule(GO:0030315)
0.1	0.6	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	0.6	GO:0043205	fibril(GO:0043205)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0031430	M band(GO:0031430)
0.1	0.3	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.3	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.5	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	4.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	1.6	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.1	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.9	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.7	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.3	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.0	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.2	GO:0005771	multivesicular body(GO:0005771)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.7	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.5	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	1.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.3	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1	0.3	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.4	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.7	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	0.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.3	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.4	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.3	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.3	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.5	GO:0017166	vinculin binding(GO:0017166)
0.1	0.2	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	0.5	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.3	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.3	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.5	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.4	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.2	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.3	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	1.2	GO:0005518	collagen binding(GO:0005518)
0.0	0.6	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.5	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.3	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.4	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.7	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.0	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.4	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	1.7	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.3	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.2	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.0	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.0	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.0	GO:0032052	bile acid binding(GO:0032052)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0002060	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.0	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	0.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	2.0	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.1	PID BMP PATHWAY	BMP receptor signaling
0.0	0.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.4	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	3.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.7	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	2.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.3	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.0	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane