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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for CREB1

Z-value: 0.33

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Transcription factors associated with CREB1

Gene Symbol	Gene ID	Gene Info
CREB1 Ensembl NCBI GeneCards UniProt	ENSG00000118260.10	cAMP responsive element binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_208365436_208365587	CREB1	28950	0.179353	0.74	2.1e-02	Click!
chr2_208395473_208395722	CREB1	769	0.520090	0.60	8.9e-02	Click!
chr2_208397856_208398007	CREB1	3103	0.254747	-0.60	9.0e-02	Click!
chr2_208462214_208462365	CREB1	22279	0.163369	0.59	9.2e-02	Click!
chr2_208395832_208396657	CREB1	1416	0.373902	0.57	1.1e-01	Click!

Activity of the CREB1 motif across conditions

Conditions sorted by the z-value of the CREB1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_20491916_20492779	0.18	CDRT15L2	CMT1A duplicated region transcript 15-like 2	9310	0.21
chr17_15689649_15690074	0.15	ENSG00000251829	.	4206	0.19
chr13_109792800_109793227	0.13	MYO16-AS2	MYO16 antisense RNA 2	38746	0.2
chr18_74773875_74774026	0.11	MBP	myelin basic protein	43267	0.18
chr1_57044587_57045121	0.11	PPAP2B	phosphatidic acid phosphatase type 2B	387	0.91
chr21_46961161_46962032	0.10	SLC19A1	solute carrier family 19 (folate transporter), member 1	156	0.96
chr6_116692035_116692441	0.10	DSE	dermatan sulfate epimerase	128	0.97
chr11_49455905_49456091	0.08	RP11-707M1.1		126372	0.06
chr4_39367062_39368041	0.08	RFC1	replication factor C (activator 1) 1, 145kDa	418	0.81
chrX_20135177_20135375	0.08	MAP7D2	MAP7 domain containing 2	241	0.9
chr8_687260_687856	0.08	ERICH1-AS1	ERICH1 antisense RNA 1	93	0.97
chr2_190444828_190446170	0.08	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1	114	0.98
chr9_17578628_17579355	0.08	SH3GL2	SH3-domain GRB2-like 2	130	0.98
chr20_32273512_32274295	0.07	E2F1	E2F transcription factor 1	307	0.81
chr19_41931658_41931809	0.07	CTC-435M10.6		469	0.62
chr14_92789494_92790350	0.07	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	27	0.99
chr5_142782115_142782536	0.07	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	23	0.99
chr3_154145836_154146602	0.07	GPR149	G protein-coupled receptor 149	1285	0.6
chrX_334679_335404	0.07	PPP2R3B	protein phosphatase 2, regulatory subunit B'', beta	262	0.94
chr12_93323322_93324013	0.06	EEA1	early endosome antigen 1	560	0.8
chr11_118230043_118230305	0.06	UBE4A	ubiquitination factor E4A	126	0.93
chr3_53276217_53276368	0.06	TKT	transketolase	13724	0.14
chr3_112279714_112280459	0.06	SLC35A5	solute carrier family 35, member A5	470	0.59
chrY_284683_285373	0.06	NA	NA	> 10⁶	NA
chr7_37487305_37488000	0.06	ELMO1	engulfment and cell motility 1	901	0.61
chr19_10527476_10527700	0.06	PDE4A	phosphodiesterase 4A, cAMP-specific	31	0.95
chr21_35987336_35987662	0.06	RCAN1	regulator of calcineurin 1	58	0.98
chr15_74657875_74658107	0.06	CTD-2311M21.3		215	0.75
chr2_60962956_60963147	0.06	ENSG00000252718	.	16276	0.19
chr17_17380267_17380681	0.06	MED9	mediator complex subunit 9	166	0.94
chr7_119450_119601	0.05	FAM20C	family with sequence similarity 20, member C	73444	0.11
chr2_130939128_130939480	0.05	MZT2B	mitotic spindle organizing protein 2B	6	0.62
chr18_53446598_53447540	0.05	TCF4	transcription factor 4	115051	0.07
chr7_23145115_23145340	0.05	KLHL7	kelch-like family member 7	126	0.97
chrX_132548696_132549413	0.05	GPC4	glypican 4	464	0.88
chr3_71834358_71834666	0.05	PROK2	prokineticin 2	155	0.96
chr15_44092835_44093206	0.05	HYPK	huntingtin interacting protein K	223	0.57
chr17_34891354_34891543	0.05	PIGW	phosphatidylinositol glycan anchor biosynthesis, class W	45	0.91
chr1_9599629_9600173	0.05	SLC25A33	solute carrier family 25 (pyrimidine nucleotide carrier), member 33	360	0.89
chr8_59323967_59324678	0.05	UBXN2B	UBX domain protein 2B	499	0.88
chr17_1532581_1533057	0.05	SLC43A2	solute carrier family 43 (amino acid system L transporter), member 2	689	0.52
chr12_133022737_133022888	0.05	MUC8	mucin 8	27914	0.17
chr16_87526385_87526690	0.05	ZCCHC14	zinc finger, CCHC domain containing 14	886	0.63
chr20_47443528_47443935	0.05	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	689	0.79
chr1_109940210_109941121	0.04	SORT1	sortilin 1	92	0.96
chr1_61549203_61549354	0.04	ENSG00000263380	.	76	0.94
chr2_26785075_26785548	0.04	C2orf70	chromosome 2 open reading frame 70	139	0.96
chr2_64836667_64836835	0.04	ENSG00000252414	.	30725	0.17
chr4_134072879_134073697	0.04	PCDH10	protocadherin 10	2818	0.44
chr9_34049001_34049202	0.04	UBAP2	ubiquitin associated protein 2	154	0.89
chr7_4901206_4901513	0.04	PAPOLB	poly(A) polymerase beta (testis specific)	266	0.91
chr11_9595385_9595551	0.04	WEE1	WEE1 G2 checkpoint kinase	240	0.9
chr7_140623410_140624534	0.04	BRAF	v-raf murine sarcoma viral oncogene homolog B	592	0.79
chrX_39548256_39548819	0.04	ENSG00000263730	.	28067	0.24
chr7_39894513_39894809	0.04	ENSG00000242855	.	33311	0.18
chr1_12040274_12040953	0.04	MFN2	mitofusin 2	244	0.89
chr9_96339036_96339199	0.04	PHF2	PHD finger protein 2	208	0.94
chr3_195384928_195385957	0.04	SDHAP2	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2	475	0.81
chrX_71933533_71934701	0.04	PHKA1	phosphorylase kinase, alpha 1 (muscle)	11	0.97
chr16_89159943_89160452	0.03	ACSF3	acyl-CoA synthetase family member 3	20	0.97
chr3_143689644_143690155	0.03	C3orf58	chromosome 3 open reading frame 58	741	0.8
chr3_87842154_87842380	0.03	ENSG00000200703	.	50468	0.17
chr2_27008928_27009181	0.03	CENPA	centromere protein A	118	0.96
chr5_170289344_170289797	0.03	RANBP17	RAN binding protein 17	696	0.71
chr18_52988378_52989650	0.03	TCF4	transcription factor 4	203	0.97
chr11_74442538_74442948	0.03	CHRDL2	chordin-like 2	313	0.84
chr3_49055259_49056395	0.03	DALRD3	DALR anticodon binding domain containing 3	170	0.84
chr2_74691535_74692741	0.03	MOGS	mannosyl-oligosaccharide glucosidase	351	0.67
chrX_138285953_138286466	0.03	FGF13	fibroblast growth factor 13	60	0.99
chr17_72732981_72733167	0.03	RAB37	RAB37, member RAS oncogene family	18	0.95
chr5_76506770_76507546	0.03	PDE8B	phosphodiesterase 8B	407	0.88
chr1_109642808_109643473	0.03	ENSG00000270066	.	325	0.81
chr4_6783649_6783989	0.03	KIAA0232	KIAA0232	550	0.79
chr15_70391403_70391876	0.03	TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)	1124	0.58
chr4_174459155_174459419	0.03	HAND2-AS1	HAND2 antisense RNA 1 (head to head)	6591	0.22
chr15_80696207_80696642	0.03	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2	269	0.71
chr11_65547664_65548343	0.03	AP5B1	adaptor-related protein complex 5, beta 1 subunit	270	0.82
chr16_52580478_52580769	0.03	TOX3	TOX high mobility group box family member 3	297	0.95
chr3_69591903_69592054	0.03	FRMD4B	FERM domain containing 4B	244	0.96
chr18_74534859_74535018	0.03	ZNF236	zinc finger protein 236	375	0.68
chr1_245134150_245135065	0.03	RP11-156E8.1	Uncharacterized protein	217	0.85
chr3_125899243_125899606	0.03	ALDH1L1	aldehyde dehydrogenase 1 family, member L1	5	0.9
chr7_3340905_3341061	0.03	SDK1	sidekick cell adhesion molecule 1	97	0.95
chr2_100105997_100106148	0.03	REV1	REV1, polymerase (DNA directed)	363	0.89
chr10_130008645_130009418	0.03	MKI67	marker of proliferation Ki-67	84382	0.11
chr1_54410859_54411299	0.03	HSPB11	heat shock protein family B (small), member 11	166	0.86
chr9_131464565_131465241	0.03	PKN3	protein kinase N3	101	0.93
chr13_110437375_110437816	0.03	IRS2	insulin receptor substrate 2	1320	0.57
chr16_1359047_1359364	0.03	UBE2I	ubiquitin-conjugating enzyme E2I	51	0.94
chr14_50235014_50236034	0.03	KLHDC2	kelch domain containing 2	638	0.62
chr10_104210416_104210610	0.03	ENSG00000269609	.	125	0.87
chr2_7057645_7057806	0.03	RNF144A	ring finger protein 144A	202	0.9
chr9_140500205_140501463	0.03	ARRDC1	arrestin domain containing 1	679	0.56
chr17_74534170_74534513	0.03	CYGB	cytoglobin	354	0.7
chr2_136289143_136290038	0.03	R3HDM1	R3H domain containing 1	503	0.62
chr16_1470975_1471179	0.03	C16orf91	chromosome 16 open reading frame 91	276	0.79
chr3_69591491_69591662	0.02	FRMD4B	FERM domain containing 4B	158	0.98
chr2_190305327_190305991	0.02	WDR75	WD repeat domain 75	500	0.87
chr12_69633375_69633694	0.02	CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	112	0.98
chr2_97482659_97482901	0.02	CNNM3	cyclin M3	793	0.53
chr16_3108546_3109349	0.02	RP11-473M20.7		139	0.86
chr10_103577050_103577916	0.02	MGEA5	meningioma expressed antigen 5 (hyaluronidase)	140	0.93
chr6_56820015_56820822	0.02	BEND6	BEN domain containing 6	248	0.86
chr19_8008965_8009156	0.02	TIMM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	255	0.8
chr11_63766571_63766823	0.02	OTUB1	OTU domain, ubiquitin aldehyde binding 1	12383	0.11
chr8_21946490_21946833	0.02	FAM160B2	family with sequence similarity 160, member B2	58	0.96
chr16_54971520_54971850	0.02	IRX5	iroquois homeobox 5	5701	0.35
chr2_85938999_85939212	0.02	ENSG00000199687	.	16355	0.12
chr22_20104378_20104805	0.02	TRMT2A	tRNA methyltransferase 2 homolog A (S. cerevisiae)	154	0.7
chr12_115889903_115890336	0.02	RP11-116D17.1	HCG2038717; Uncharacterized protein	89302	0.1
chr15_52860024_52861356	0.02	ARPP19	cAMP-regulated phosphoprotein, 19kDa	339	0.87
chr1_63782781_63783608	0.02	RP4-792G4.2		4006	0.2
chr1_1589957_1590616	0.02	CDK11B	cyclin-dependent kinase 11B	187	0.75
chr1_22108808_22109469	0.02	USP48	ubiquitin specific peptidase 48	346	0.89
chr7_56019535_56020015	0.02	MRPS17	mitochondrial ribosomal protein S17	119	0.72
chr11_568685_568932	0.02	ENSG00000199038	.	610	0.48
chr19_13264252_13264621	0.02	CTC-250I14.6		90	0.93
chr9_132382165_132382732	0.02	C9orf50	chromosome 9 open reading frame 50	607	0.62
chr7_99156308_99157048	0.02	ZNF655	zinc finger protein 655	193	0.77
chr20_48595704_48595927	0.02	SNAI1	snail family zinc finger 1	3721	0.18
chr7_113724609_113725113	0.02	FOXP2	forkhead box P2	1754	0.44
chr10_108924530_108924681	0.02	SORCS1	sortilin-related VPS10 domain containing receptor 1	313	0.95
chr11_77185235_77185792	0.02	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	167	0.92
chr2_61696387_61697458	0.02	USP34	ubiquitin specific peptidase 34	982	0.45
chr20_3994903_3996170	0.02	RNF24	ring finger protein 24	500	0.83
chr1_208132304_208132634	0.02	CD34	CD34 molecule	47722	0.19
chr15_74219902_74220340	0.02	LOXL1-AS1	LOXL1 antisense RNA 1	6	0.96
chr16_3207596_3208760	0.02	CASP16	caspase 16, apoptosis-related cysteine peptidase (putative)	13934	0.08
chr2_176944534_176944961	0.02	EVX2	even-skipped homeobox 2	3894	0.12
chr12_104531819_104531970	0.02	NFYB	nuclear transcription factor Y, beta	87	0.97
chr1_90460754_90461861	0.02	ZNF326	zinc finger protein 326	580	0.8
chr10_112403975_112404246	0.02	RBM20	RNA binding motif protein 20	45	0.96
chr1_233463556_233464041	0.02	MLK4	Mitogen-activated protein kinase kinase kinase MLK4	284	0.94
chrX_119149654_119149897	0.02	RP4-755D9.1		20426	0.16
chr9_134954308_134955306	0.02	MED27	mediator complex subunit 27	446	0.89
chr9_130699622_130700109	0.02	DPM2	dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit	257	0.5
chr4_74904304_74905084	0.02	CXCL3	chemokine (C-X-C motif) ligand 3	288	0.87
chrY_21238831_21239141	0.02	ENSG00000252766	.	58013	0.16
chr4_96469881_96470326	0.02	UNC5C	unc-5 homolog C (C. elegans)	20	0.69
chr3_142607235_142608274	0.02	PCOLCE2	procollagen C-endopeptidase enhancer 2	13	0.98
chr14_33408703_33409010	0.02	NPAS3	neuronal PAS domain protein 3	333	0.94
chr8_10696975_10697533	0.02	PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1	27	0.57
chr1_9882638_9884014	0.02	CLSTN1	calsyntenin 1	716	0.65
chr8_135725075_135725586	0.02	ZFAT	zinc finger and AT hook domain containing	49	0.99
chr19_56156604_56156918	0.02	ZNF581	zinc finger protein 581	1585	0.15
chr9_77642770_77643186	0.02	C9orf41	chromosome 9 open reading frame 41	211	0.93
chr11_8290078_8290567	0.02	LMO1	LIM domain only 1 (rhombotin 1)	59	0.98
chr15_68155525_68155920	0.02	ENSG00000206625	.	23339	0.22
chr2_223155673_223155824	0.02	CCDC140	coiled-coil domain containing 140	7118	0.2
chr2_27578903_27579940	0.02	GTF3C2	general transcription factor IIIC, polypeptide 2, beta 110kDa	62	0.77
chr2_152493968_152494122	0.02	NEB	nebulin	53912	0.17
chr16_88870149_88870541	0.02	CDT1	chromatin licensing and DNA replication factor 1	724	0.48
chr7_155249437_155250320	0.02	EN2	engrailed homeobox 2	946	0.59
chr6_170921254_170921775	0.02	PDCD2	programmed cell death 2	27766	0.19
chr2_238395971_238396408	0.02	MLPH	melanophilin	270	0.92
chr13_53024209_53024738	0.02	VPS36	vacuolar protein sorting 36 homolog (S. cerevisiae)	284	0.9
chr10_28287400_28288216	0.02	ARMC4	armadillo repeat containing 4	169	0.97
chr3_100053843_100054079	0.02	NIT2	nitrilase family, member 2	306	0.91
chrX_334213_334384	0.02	PPP2R3B	protein phosphatase 2, regulatory subunit B'', beta	481	0.86
chr15_42840348_42841494	0.02	LRRC57	leucine rich repeat containing 57	49	0.54
chr14_100706520_100706671	0.02	YY1	YY1 transcription factor	499	0.64
chr6_101849901_101850127	0.02	GRIK2	glutamate receptor, ionotropic, kainate 2	2860	0.43
chr12_51818617_51818968	0.02	SLC4A8	solute carrier family 4, sodium bicarbonate cotransporter, member 8	109	0.81
chrY_284220_284379	0.02	NA	NA	> 10⁶	NA
chr1_41249080_41249567	0.02	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4	361	0.82
chr3_197354198_197354750	0.02	AC024560.3		245	0.93
chr20_33413142_33413293	0.02	NCOA6	nuclear receptor coactivator 6	235	0.93
chrX_153402310_153402730	0.01	OPN1LW	opsin 1 (cone pigments), long-wave-sensitive	7178	0.14
chr22_51020587_51021277	0.01	CHKB	choline kinase beta	496	0.39
chr8_41997342_41997944	0.01	RP11-589C21.5		12638	0.17
chr6_137244870_137245021	0.01	SLC35D3	solute carrier family 35, member D3	1543	0.4
chr2_11051733_11051998	0.01	KCNF1	potassium voltage-gated channel, subfamily F, member 1	198	0.95
chr5_141404364_141404742	0.01	GNPDA1	glucosamine-6-phosphate deaminase 1	11947	0.17
chr20_307052_307593	0.01	SOX12	SRY (sex determining region Y)-box 12	1083	0.33
chr11_73498863_73499083	0.01	MRPL48	mitochondrial ribosomal protein L48	2	0.97
chr12_95942120_95942537	0.01	USP44	ubiquitin specific peptidase 44	246	0.94
chr11_64569817_64570601	0.01	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	438	0.72
chr11_123525466_123525691	0.01	SCN3B	sodium channel, voltage-gated, type III, beta subunit	136	0.96
chr12_112546417_112546609	0.01	NAA25	N(alpha)-acetyltransferase 25, NatB auxiliary subunit	34	0.97
chr17_7144804_7145679	0.01	GABARAP	GABA(A) receptor-associated protein	103	0.89
chr17_8042262_8042413	0.01	PER1	period circadian clock 1	7005	0.08
chr10_70588000_70588364	0.01	STOX1	storkhead box 1	619	0.68
chr17_37910669_37910916	0.01	GRB7	growth factor receptor-bound protein 7	12287	0.11
chr7_35076877_35077068	0.01	DPY19L1	dpy-19-like 1 (C. elegans)	681	0.8
chr2_71115848_71116159	0.01	VAX2	ventral anterior homeobox 2	11717	0.13
chr3_96531977_96533205	0.01	EPHA6	EPH receptor A6	834	0.76
chr11_2466604_2466835	0.01	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	498	0.74
chr16_84149538_84150449	0.01	MBTPS1	membrane-bound transcription factor peptidase, site 1	407	0.6
chr16_46660648_46660928	0.01	SHCBP1	SHC SH2-domain binding protein 1	5250	0.2
chr12_133405892_133406043	0.01	GOLGA3	golgin A3	528	0.72
chr10_12392249_12392465	0.01	CAMK1D	calcium/calmodulin-dependent protein kinase ID	625	0.72
chr2_28616306_28616795	0.01	FOSL2	FOS-like antigen 2	825	0.43
chr15_99557942_99558631	0.01	PGPEP1L	pyroglutamyl-peptidase I-like	7262	0.22
chr10_32636312_32636863	0.01	RP11-135A24.2		262	0.56
chr1_17248321_17248578	0.01	CROCC	ciliary rootlet coiled-coil, rootletin	4	0.97
chr16_66785084_66785300	0.01	DYNC1LI2	dynein, cytoplasmic 1, light intermediate chain 2	305	0.86
chr17_18086808_18086984	0.01	ALKBH5	alkB, alkylation repair homolog 5 (E. coli)	504	0.6
chr2_92027935_92028159	0.01	IGKV1OR-1	immunoglobulin kappa variable 1/OR-1 (pseudogene)	22065	0.23
chr19_47951006_47951312	0.01	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2	23961	0.12
chr1_64059512_64060140	0.01	PGM1	phosphoglucomutase 1	346	0.87

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	GO:0097576	vacuole fusion(GO:0097576)
0.1	GO:0008354	germ cell migration(GO:0008354)
0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1

Results for CREB1

Z-value: 0.33

Motif logo

Transcription factors associated with CREB1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the CREB1 motif across conditions

Conditions sorted by the z-value of the CREB1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: