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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CREB3L1_CREB3

Z-value: 0.82

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Transcription factors associated with CREB3L1_CREB3

Gene Symbol Gene ID Gene Info
CREB3L1
ENSG00000157613.6 CREB3L1
CREB3
ENSG00000107175.6 CREB3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
CREB3chr9_35728074_3572827641570.0888400.618.2e-02Click!
CREB3chr9_35727770_3572798844530.0868460.561.2e-01Click!
CREB3chr9_35727615_3572776646420.0857520.551.2e-01Click!
CREB3chr9_35727078_3572722951790.0832190.501.7e-01Click!
CREB3chr9_35714007_35714158182500.066425-0.462.1e-01Click!
CREB3L1chr11_46307086_4630728879590.1768900.511.6e-01Click!
CREB3L1chr11_46300696_4630084715430.3667490.501.7e-01Click!
CREB3L1chr11_46300240_4630051811510.4649260.422.6e-01Click!
CREB3L1chr11_46340567_4634077079600.160269-0.422.6e-01Click!
CREB3L1chr11_46302791_4630323637850.2117080.383.2e-01Click!

Activity of the CREB3L1_CREB3 motif across conditions

Conditions sorted by the z-value of the CREB3L1_CREB3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_15722330_15722494 0.58 MEOX2
 mesenchyme homeobox 2
 4025
 0.29
chr16_1014713_1014988 0.43 LMF1
 lipase maturation factor 1
 728
 0.55
chr1_170632304_170632495 0.41 PRRX1
 paired related homeobox 1
 124
 0.98
chr8_70042166_70042317 0.40 ENSG00000238808
 .
 19432
 0.3
chr7_100200956_100201118 0.36 PCOLCE-AS1
 PCOLCE antisense RNA 1
 379
 0.65
chr5_141443601_141443885 0.36 NDFIP1
 Nedd4 family interacting protein 1
 44327
 0.13
chr1_27445743_27446018 0.34 SLC9A1
 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
 35093
 0.15
chr15_99259160_99259373 0.34 IGF1R
 insulin-like growth factor 1 receptor
 8206
 0.26
chr2_62444590_62444741 0.33 B3GNT2
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
 2012
 0.3
chr9_80055112_80055292 0.33 RP11-466A17.1
16009
 0.24
chr4_152146952_152147499 0.32 SH3D19
 SH3 domain containing 19
 7
 0.98
chr10_6125711_6125919 0.32 RBM17
 RNA binding motif protein 17
 5135
 0.17
chr8_66953995_66954146 0.31 DNAJC5B
 DnaJ (Hsp40) homolog, subfamily C, member 5 beta
 1642
 0.5
chr2_198540490_198540682 0.31 RFTN2
 raftlin family member 2
 133
 0.96
chr9_137288070_137288221 0.31 RXRA
 retinoid X receptor, alpha
 10283
 0.23
chr5_171560548_171560699 0.30 ENSG00000266671
 .
 52643
 0.12
chr12_129291969_129292120 0.29 SLC15A4
 solute carrier family 15 (oligopeptide transporter), member 4
 2859
 0.35
chr16_88658218_88658369 0.29 ZC3H18
 zinc finger CCCH-type containing 18
 5268
 0.15
chr1_204010490_204010911 0.29 SOX13
 SRY (sex determining region Y)-box 13
 32032
 0.15
chr2_218221473_218221860 0.27 ENSG00000251982
 .
 105387
 0.08
chr2_218867466_218867778 0.27 TNS1
 tensin 1
 96
 0.97
chr20_44463514_44463665 0.26 SNX21
 sorting nexin family member 21
 814
 0.34
chr1_23883319_23883470 0.26 ID3
 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
 2891
 0.25
chr17_57407133_57407390 0.26 YPEL2
 yippee-like 2 (Drosophila)
 1802
 0.33
chr3_27523238_27523389 0.25 SLC4A7
 solute carrier family 4, sodium bicarbonate cotransporter, member 7
 2525
 0.3
chr7_23274495_23274692 0.24 GPNMB
 glycoprotein (transmembrane) nmb
 11589
 0.2
chr1_12235343_12235565 0.24 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 8394
 0.16
chr21_17445369_17445660 0.24 ENSG00000252273
 .
 37685
 0.23
chr10_44879097_44879375 0.24 CXCL12
 chemokine (C-X-C motif) ligand 12
 1255
 0.52
chr2_101541390_101541618 0.23 NPAS2
 neuronal PAS domain protein 2
 104
 0.97
chr1_224008752_224008903 0.23 TP53BP2
 tumor protein p53 binding protein, 2
 6797
 0.28
chr16_89830973_89831469 0.23 FANCA
 Fanconi anemia, complementation group A
 19751
 0.11
chrX_23686647_23686860 0.23 PRDX4
 peroxiredoxin 4
 1085
 0.58
chr1_66846122_66846273 0.23 PDE4B
 phosphodiesterase 4B, cAMP-specific
 26132
 0.25
chr11_63686882_63687128 0.22 RCOR2
 REST corepressor 2
 2689
 0.17
chr6_133254252_133254403 0.22 ENSG00000200534
 .
 115969
 0.05
chr6_117717394_117717545 0.22 ROS1
 c-ros oncogene 1 , receptor tyrosine kinase
 29549
 0.15
chrX_100872700_100873033 0.22 ARMCX6
 armadillo repeat containing, X-linked 6
 125
 0.93
chr10_124254663_124255115 0.22 HTRA1
 HtrA serine peptidase 1
 11318
 0.2
chr17_66082289_66082451 0.22 LINC00674
 long intergenic non-protein coding RNA 674
 15679
 0.18
chr1_178991033_178991223 0.21 FAM20B
 family with sequence similarity 20, member B
 3811
 0.29
chr1_170640082_170640341 0.21 PRRX1
 paired related homeobox 1
 7133
 0.3
chr1_90331815_90331966 0.20 LRRC8D
 leucine rich repeat containing 8 family, member D
 19751
 0.22
chr19_42130849_42131075 0.20 CEACAM4
 carcinoembryonic antigen-related cell adhesion molecule 4
 2480
 0.23
chr5_121509459_121509610 0.20 CTC-441N14.1
17824
 0.18
chr6_148830339_148830689 0.20 ENSG00000223322
 .
 14862
 0.29
chr20_19956104_19956326 0.19 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 41545
 0.15
chr2_208199066_208199401 0.19 ENSG00000221628
 .
 65085
 0.12
chr6_27573492_27573857 0.19 ENSG00000206671
 .
 9483
 0.2
chr4_11652300_11652527 0.19 HS3ST1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
 221024
 0.02
chr6_1885704_1885932 0.19 FOXC1
 forkhead box C1
 275137
 0.01
chr17_43312812_43312963 0.19 FMNL1
 formin-like 1
 5555
 0.1
chr3_72940504_72940835 0.19 GXYLT2
 glucoside xylosyltransferase 2
 3445
 0.28
chr1_217262846_217263329 0.19 ESRRG
 estrogen-related receptor gamma
 111
 0.98
chr5_88171366_88171720 0.19 MEF2C
 myocyte enhancer factor 2C
 2251
 0.36
chr8_23605481_23605654 0.19 ENSG00000216123
 .
 20591
 0.16
chr3_45265689_45266072 0.19 TMEM158
 transmembrane protein 158 (gene/pseudogene)
 1890
 0.38
chr10_45719589_45719755 0.18 ENSG00000207071
 .
 35328
 0.17
chr5_1879697_1879902 0.18 IRX4
 iroquois homeobox 4
 3059
 0.2
chr4_114063101_114063433 0.18 ANK2
 ankyrin 2, neuronal
 3521
 0.33
chr2_96658143_96658593 0.18 ANKRD36C
 ankyrin repeat domain 36C
 827
 0.58
chr5_92923285_92923507 0.17 ENSG00000237187
 .
 2042
 0.33
chrX_41535546_41535697 0.17 ENSG00000242559
 .
 7098
 0.18
chr5_151060620_151060937 0.17 SPARC
 secreted protein, acidic, cysteine-rich (osteonectin)
 4013
 0.17
chr12_52241613_52241902 0.17 AC068987.1
 HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
 37968
 0.13
chr6_160876831_160877004 0.17 LPAL2
 lipoprotein, Lp(a)-like 2, pseudogene
 55122
 0.15
chr8_9088633_9088784 0.17 ENSG00000207415
 .
 56380
 0.12
chr17_6555060_6555332 0.17 C17orf100
 chromosome 17 open reading frame 100
 225
 0.49
chr5_172234489_172234691 0.16 ERGIC1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 26688
 0.12
chr17_66511128_66511617 0.16 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
 108
 0.97
chr15_101728923_101729679 0.16 CHSY1
 chondroitin sulfate synthase 1
 62836
 0.1
chr2_85765868_85766150 0.16 MAT2A
 methionine adenosyltransferase II, alpha
 279
 0.82
chr3_194118884_194119077 0.16 GP5
 glycoprotein V (platelet)
 103
 0.96
chr17_1959923_1960311 0.16 HIC1
 hypermethylated in cancer 1
 513
 0.59
chrX_128893788_128893939 0.16 SASH3
 SAM and SH3 domain containing 3
 20097
 0.17
chr18_22813939_22814258 0.16 ZNF521
 zinc finger protein 521
 2604
 0.41
chr17_49027559_49028056 0.16 SPAG9
 sperm associated antigen 9
 43491
 0.13
chr15_74988471_74988935 0.16 EDC3
 enhancer of mRNA decapping 3
 70
 0.97
chr2_3307191_3307353 0.16 TSSC1-IT1
 TSSC1 intronic transcript 1 (non-protein coding)
 2036
 0.4
chr3_72640881_72641032 0.16 ENSG00000199469
 .
 15114
 0.22
chr20_36825206_36825357 0.16 TGM2
 transglutaminase 2
 30301
 0.14
chr6_149803641_149803913 0.15 ZC3H12D
 zinc finger CCCH-type containing 12D
 492
 0.77
chr22_38864095_38864404 0.15 KDELR3
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
 166
 0.93
chr20_56803890_56804242 0.15 ANKRD60
 ankyrin repeat domain 60
 357
 0.88
chr21_44061431_44061649 0.15 AP001626.2
9814
 0.18
chr1_204332360_204332939 0.15 PLEKHA6
 pleckstrin homology domain containing, family A member 6
 3605
 0.22
chr2_110656312_110656910 0.15 LIMS3
 LIM and senescent cell antigen-like domains 3
 343
 0.93
chr6_136547273_136547517 0.15 RP13-143G15.4
662
 0.72
chr19_39140182_39140489 0.15 ACTN4
 actinin, alpha 4
 1957
 0.23
chr5_54899055_54899206 0.15 PPAP2A
 phosphatidic acid phosphatase type 2A
 68252
 0.1
chr16_31104780_31104975 0.15 VKORC1
 vitamin K epoxide reductase complex, subunit 1
 55
 0.91
chr3_73673648_73674178 0.15 PDZRN3
 PDZ domain containing ring finger 3
 78
 0.96
chr4_177304632_177304846 0.15 RP11-87F15.2
63130
 0.12
chr20_24008090_24008393 0.15 GGTLC1
 gamma-glutamyltransferase light chain 1
 38825
 0.2
chr16_86602293_86602507 0.15 RP11-463O9.5
1033
 0.41
chr7_37797263_37797414 0.15 GPR141
 G protein-coupled receptor 141
 17342
 0.25
chr7_37755543_37755694 0.15 GPR141
 G protein-coupled receptor 141
 24378
 0.21
chr2_109271526_109272143 0.15 LIMS1
 LIM and senescent cell antigen-like domains 1
 325
 0.91
chr15_36699845_36700050 0.15 C15orf41
 chromosome 15 open reading frame 41
 171865
 0.04
chr4_155953158_155953309 0.15 RP11-92A5.2
176350
 0.03
chr20_47435468_47435675 0.15 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 8849
 0.27
chr6_13926565_13926716 0.14 RNF182
 ring finger protein 182
 1216
 0.61
chr8_29513803_29514023 0.14 ENSG00000221003
 .
 272208
 0.01
chr20_61555717_61555868 0.14 DIDO1
 death inducer-obliterator 1
 2029
 0.26
chr15_68545515_68545666 0.14 CLN6
 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
 3854
 0.2
chr2_112250892_112251415 0.14 ENSG00000266139
 .
 172485
 0.03
chrY_19868908_19869238 0.14 ENSG00000252513
 .
 31969
 0.22
chr18_59537327_59537518 0.14 RNF152
 ring finger protein 152
 23570
 0.27
chr13_96297004_96297314 0.14 DZIP1
 DAZ interacting zinc finger protein 1
 202
 0.95
chr7_38351039_38351457 0.14 STARD3NL
 STARD3 N-terminal like
 133251
 0.05
chr1_119521934_119522435 0.14 TBX15
 T-box 15
 8244
 0.28
chr3_150088154_150088521 0.14 TSC22D2
 TSC22 domain family, member 2
 37785
 0.2
chrY_2803195_2803357 0.14 ZFY
 zinc finger protein, Y-linked
 46
 0.98
chr2_89028504_89028655 0.14 RPIA
 ribose 5-phosphate isomerase A
 37417
 0.1
chr3_81766350_81766631 0.14 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 26290
 0.28
chr5_54898758_54898909 0.14 PPAP2A
 phosphatidic acid phosphatase type 2A
 67955
 0.1
chr19_2775423_2775574 0.14 SGTA
 small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
 4719
 0.12
chr10_14592515_14592666 0.13 FAM107B
 family with sequence similarity 107, member B
 1921
 0.42
chr17_18061433_18061699 0.13 MYO15A
 myosin XVA
 56
 0.96
chr12_107350500_107350907 0.13 C12orf23
 chromosome 12 open reading frame 23
 140
 0.94
chr19_16438433_16439148 0.13 KLF2
 Kruppel-like factor 2
 3139
 0.19
chr6_72129092_72129273 0.13 ENSG00000207827
 .
 15858
 0.22
chr13_31665227_31665378 0.13 HSPH1
 heat shock 105kDa/110kDa protein 1
 47403
 0.17
chr10_121161636_121161837 0.13 GRK5
 G protein-coupled receptor kinase 5
 23787
 0.17
chr10_135334394_135334545 0.13 CYP2E1
 cytochrome P450, family 2, subfamily E, polypeptide 1
 559
 0.69
chr16_30825894_30826089 0.13 ZNF629
 zinc finger protein 629
 27468
 0.08
chr11_122050907_122051108 0.13 ENSG00000207994
 .
 27991
 0.16
chr22_24092778_24093143 0.13 ZNF70
 zinc finger protein 70
 319
 0.77
chr1_156116419_156116573 0.13 SEMA4A
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
 661
 0.56
chr16_2184293_2184536 0.13 ENSG00000265867
 .
 1294
 0.14
chr10_29977190_29977386 0.13 ENSG00000222092
 .
 23556
 0.21
chr10_79291588_79291953 0.13 ENSG00000199592
 .
 55037
 0.15
chr22_23799075_23799226 0.13 ZDHHC8P1
 zinc finger, DHHC-type containing 8 pseudogene 1
 54806
 0.11
chr9_139221044_139221275 0.12 GPSM1
 G-protein signaling modulator 1
 773
 0.48
chrY_20310575_20310758 0.12 ENSG00000252166
 .
 31932
 0.23
chr19_6067548_6067787 0.12 CTC-232P5.3
297
 0.87
chr11_131487115_131487266 0.12 NTM
 neurotrimin
 35285
 0.18
chr16_31117201_31117391 0.12 BCKDK
 branched chain ketoacid dehydrogenase kinase
 132
 0.87
chr10_126916601_126916752 0.12 CTBP2
 C-terminal binding protein 2
 67046
 0.13
chr2_97466776_97466927 0.12 ENSG00000264157
 .
 2836
 0.19
chr1_23866282_23866470 0.12 E2F2
 E2F transcription factor 2
 8664
 0.18
chr12_110510869_110511513 0.12 C12orf76
 chromosome 12 open reading frame 76
 300
 0.91
chr6_151188569_151188720 0.12 MTHFD1L
 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
 951
 0.67
chr19_58350280_58350431 0.12 ZNF587B
 zinc finger protein 587B
 8674
 0.1
chr6_80175862_80176013 0.12 LCA5
 Leber congenital amaurosis 5
 71188
 0.12
chr3_156272520_156272859 0.12 SSR3
 signal sequence receptor, gamma (translocon-associated protein gamma)
 55
 0.98
chr7_5517932_5518149 0.12 ENSG00000238394
 .
 6986
 0.13
chr11_15601328_15601479 0.12 ENSG00000253072
 .
 97964
 0.09
chrY_14774767_14775041 0.12 USP9Y
 ubiquitin specific peptidase 9, Y-linked
 38256
 0.23
chr10_89420631_89420782 0.12 PAPSS2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
 2
 0.96
chr20_4707737_4707988 0.12 PRND
 prion protein 2 (dublet)
 5306
 0.21
chr2_242210722_242211682 0.12 HDLBP
 high density lipoprotein binding protein
 184
 0.93
chr5_32490035_32490410 0.12 SUB1
 SUB1 homolog (S. cerevisiae)
 41517
 0.15
chr17_42637074_42637426 0.12 FZD2
 frizzled family receptor 2
 2325
 0.29
chr4_17818884_17819094 0.12 NCAPG
 non-SMC condensin I complex, subunit G
 6333
 0.21
chr11_65194450_65194730 0.12 ENSG00000245532
 .
 17339
 0.11
chr2_146281977_146282128 0.12 ENSG00000253036
 .
 189414
 0.03
chr6_27463328_27463580 0.12 ZNF184
 zinc finger protein 184
 22557
 0.21
chr2_65215337_65216235 0.12 SLC1A4
 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
 162
 0.95
chr1_53528292_53528443 0.12 PODN
 podocan
 482
 0.76
chr1_145576060_145576252 0.12 PIAS3
 protein inhibitor of activated STAT, 3
 132
 0.93
chr4_80997222_80997373 0.12 ANTXR2
 anthrax toxin receptor 2
 2671
 0.39
chr7_91808687_91808971 0.12 LRRD1
 leucine-rich repeats and death domain containing 1
 16
 0.97
chr2_179142472_179142690 0.12 OSBPL6
 oxysterol binding protein-like 6
 7073
 0.26
chr10_92794688_92794839 0.11 ENSG00000201604
 .
 112171
 0.06
chr2_87756158_87756657 0.11 RP11-1399P15.1
21146
 0.27
chr17_17380267_17380681 0.11 MED9
 mediator complex subunit 9
 166
 0.94
chr1_65400046_65400380 0.11 JAK1
 Janus kinase 1
 31974
 0.2
chr16_31084353_31084557 0.11 ZNF668
 zinc finger protein 668
 307
 0.69
chr14_103490453_103490773 0.11 CDC42BPB
 CDC42 binding protein kinase beta (DMPK-like)
 33186
 0.15
chr14_23834178_23834353 0.11 EFS
 embryonal Fyn-associated substrate
 154
 0.88
chr9_95523893_95524044 0.11 BICD2
 bicaudal D homolog 2 (Drosophila)
 3126
 0.26
chr13_36491458_36491923 0.11 DCLK1
 doublecortin-like kinase 1
 61911
 0.15
chr2_121650695_121650846 0.11 GLI2
 GLI family zinc finger 2
 95849
 0.08
chr2_105371997_105372148 0.11 ENSG00000207249
 .
 22380
 0.21
chr12_68915355_68915540 0.11 RAP1B
 RAP1B, member of RAS oncogene family
 89172
 0.08
chr3_52566513_52566726 0.11 NT5DC2
 5'-nucleotidase domain containing 2
 928
 0.41
chr17_66957491_66957642 0.11 ABCA8
 ATP-binding cassette, sub-family A (ABC1), member 8
 6074
 0.25
chr2_97593731_97594362 0.11 ENSG00000252845
 .
 28506
 0.12
chr11_68596728_68596879 0.11 CPT1A
 carnitine palmitoyltransferase 1A (liver)
 10349
 0.2
chr1_104112980_104113131 0.11 AMY2B
 amylase, alpha 2B (pancreatic)
 5402
 0.19
chr2_111230131_111230333 0.11 LIMS3
 LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein
 161
 0.49
chr5_81065115_81065411 0.11 SSBP2
 single-stranded DNA binding protein 2
 18191
 0.28
chr13_99506197_99506352 0.11 DOCK9
 dedicator of cytokinesis 9
 1964
 0.38
chr3_40566463_40567204 0.11 ZNF621
 zinc finger protein 621
 74
 0.97
chr22_29427564_29428192 0.11 ZNRF3-AS1
 ZNRF3 antisense RNA 1
 414
 0.8
chrX_11162485_11162636 0.10 ENSG00000207151
 .
 28247
 0.2
chr2_96915646_96915797 0.10 TMEM127
 transmembrane protein 127
 10612
 0.14
chr2_43144698_43145013 0.10 HAAO
 3-hydroxyanthranilate 3,4-dioxygenase
 125123
 0.05
chr10_64893167_64893712 0.10 NRBF2
 nuclear receptor binding factor 2
 354
 0.88
chr10_30348565_30348787 0.10 KIAA1462
 KIAA1462
 223
 0.96
chr12_121570606_121571339 0.10 P2RX7
 purinergic receptor P2X, ligand-gated ion channel, 7
 198
 0.94
chr2_102803614_102803903 0.10 IL1RL2
 interleukin 1 receptor-like 2
 16
 0.98
chr3_105086242_105086708 0.10 ALCAM
 activated leukocyte cell adhesion molecule
 288
 0.96
chr15_58798000_58798151 0.10 RP11-355N15.1
7141
 0.18
chr8_82007271_82007422 0.10 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 16957
 0.27
chr3_75445432_75445834 0.10 ENSG00000266685
 .
 27136
 0.18
chr4_173063385_173063536 0.10 GALNTL6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
 89864
 0.11
chr1_7764600_7765026 0.10 CAMTA1
 calmodulin binding transcription activator 1
 31655
 0.17
chr20_3451275_3451544 0.10 ATRN
 attractin
 278
 0.91

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of CREB3L1_CREB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.0 GO:0021508 floor plate formation(GO:0021508)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.0 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0090026 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0061042 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.0 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.0 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.0 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.0 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.1 GO:0030903 notochord development(GO:0030903)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.0 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0015295 solute:proton symporter activity(GO:0015295)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.1 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex