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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for CREB3L2

Z-value: 0.95

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Transcription factors associated with CREB3L2

Gene Symbol Gene ID Gene Info
CREB3L2
ENSG00000182158.10 cAMP responsive element binding protein 3 like 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_137671037_137671188CREB3L2156810.1880740.932.7e-04Click!
chr7_137683078_137683229CREB3L236400.2462520.684.4e-02Click!
chr7_137665787_137665938CREB3L2209310.1770260.675.0e-02Click!
chr7_137671468_137671947CREB3L2150860.1892620.617.9e-02Click!
chr7_137685974_137686842CREB3L23850.8687880.599.6e-02Click!

Activity of the CREB3L2 motif across conditions

Conditions sorted by the z-value of the CREB3L2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_102106282_102106433 0.52 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
 1339
 0.56
chr2_151337593_151337891 0.40 RND3
 Rho family GTPase 3
 4154
 0.38
chr2_234176635_234176786 0.35 ENSG00000252010
 .
 7663
 0.14
chr2_27341761_27341954 0.34 CGREF1
 cell growth regulator with EF-hand domain 1
 41
 0.94
chr3_19988451_19988692 0.34 RAB5A
 RAB5A, member RAS oncogene family
 0
 0.54
chr1_118728319_118728470 0.34 SPAG17
 sperm associated antigen 17
 548
 0.86
chr13_24211833_24211984 0.34 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 58389
 0.14
chr3_29376770_29376984 0.33 ENSG00000216169
 .
 34035
 0.18
chr15_96952055_96952206 0.33 AC087477.1
 Uncharacterized protein
 47643
 0.13
chr9_95970167_95970323 0.33 WNK2
 WNK lysine deficient protein kinase 2
 23020
 0.19
chr5_178770702_178770853 0.32 ADAMTS2
 ADAM metallopeptidase with thrombospondin type 1 motif, 2
 1654
 0.49
chr22_44222171_44222754 0.32 RP3-388M5.9
14089
 0.16
chr3_123602332_123603013 0.31 MYLK
 myosin light chain kinase
 477
 0.85
chr17_47210248_47210565 0.31 B4GALNT2
 beta-1,4-N-acetyl-galactosaminyl transferase 2
 77
 0.97
chr5_114795809_114796168 0.30 FEM1C
 fem-1 homolog c (C. elegans)
 84603
 0.08
chr4_120987081_120987232 0.30 RP11-679C8.2
957
 0.45
chr12_2185524_2185819 0.30 CACNA1C
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 22942
 0.16
chr12_105476938_105477089 0.30 ALDH1L2
 aldehyde dehydrogenase 1 family, member L2
 1328
 0.39
chr15_41575867_41576018 0.30 CHP1
 calcineurin-like EF-hand protein 1
 26834
 0.13
chr6_107816329_107816751 0.29 SOBP
 sine oculis binding protein homolog (Drosophila)
 5378
 0.23
chr2_25934983_25935152 0.29 ENSG00000222070
 .
 9994
 0.19
chr10_119303143_119303333 0.29 EMX2
 empty spiracles homeobox 2
 729
 0.61
chr5_154070973_154071336 0.28 ENSG00000221552
 .
 5818
 0.17
chr2_241496900_241497119 0.27 ANKMY1
 ankyrin repeat and MYND domain containing 1
 370
 0.78
chrY_15864765_15864916 0.27 KALP
 Kallmann syndrome sequence pseudogene
 1304
 0.55
chrX_129245775_129245926 0.27 ELF4
 E74-like factor 4 (ets domain transcription factor)
 1159
 0.52
chr22_28181066_28181439 0.27 MN1
 meningioma (disrupted in balanced translocation) 1
 16234
 0.25
chr11_69460305_69460629 0.26 CCND1
 cyclin D1
 4493
 0.24
chr6_134211072_134211606 0.26 TCF21
 transcription factor 21
 866
 0.5
chr4_15481095_15481291 0.25 CC2D2A
 coiled-coil and C2 domain containing 2A
 346
 0.89
chr6_147235316_147235787 0.25 STXBP5-AS1
 STXBP5 antisense RNA 1
 1470
 0.57
chr8_17193981_17194132 0.25 MTMR7
 myotubularin related protein 7
 24874
 0.21
chr9_131006944_131007312 0.25 ENSG00000207581
 .
 19
 0.68
chr10_5617288_5617517 0.24 CALML3-AS1
 CALML3 antisense RNA 1
 49193
 0.09
chr16_28213590_28213741 0.24 XPO6
 exportin 6
 9132
 0.18
chr4_157890038_157890662 0.23 PDGFC
 platelet derived growth factor C
 1705
 0.41
chr10_79261419_79261649 0.23 ENSG00000199592
 .
 85273
 0.09
chr2_238316542_238316753 0.23 COL6A3
 collagen, type VI, alpha 3
 6144
 0.22
chr3_58037164_58037339 0.23 FLNB
 filamin B, beta
 26805
 0.22
chr21_46476184_46476390 0.22 AP001579.1
 Uncharacterized protein
 16640
 0.14
chr20_19956104_19956326 0.22 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 41545
 0.15
chr12_77257769_77258091 0.22 RP11-461F16.3
14043
 0.22
chr3_30722457_30722608 0.22 RP11-1024P17.1
16621
 0.27
chr20_22559380_22559531 0.22 FOXA2
 forkhead box A2
 5646
 0.34
chr17_39472322_39472473 0.22 KRTAP17-1
 keratin associated protein 17-1
 450
 0.64
chr15_29396229_29396380 0.21 APBA2
 amyloid beta (A4) precursor protein-binding, family A, member 2
 59777
 0.14
chr15_101629242_101629566 0.21 RP11-505E24.2
3133
 0.3
chr6_7910547_7910822 0.21 TXNDC5
 thioredoxin domain containing 5 (endoplasmic reticulum)
 363
 0.93
chr9_126088906_126089175 0.21 CRB2
 crumbs homolog 2 (Drosophila)
 29409
 0.19
chr20_50720613_50721041 0.21 ZFP64
 ZFP64 zinc finger protein
 562
 0.86
chr10_128076215_128076453 0.21 ADAM12
 ADAM metallopeptidase domain 12
 690
 0.79
chr3_100708920_100709071 0.21 ABI3BP
 ABI family, member 3 (NESH) binding protein
 3302
 0.32
chr1_55792590_55792741 0.20 ENSG00000199831
 .
 49860
 0.14
chr1_11791745_11791900 0.20 AGTRAP
 angiotensin II receptor-associated protein
 4319
 0.14
chr1_15653496_15653771 0.20 RP3-467K16.7
8327
 0.16
chr3_131221719_131221870 0.20 MRPL3
 mitochondrial ribosomal protein L3
 1
 0.98
chr13_52377985_52378296 0.20 DHRS12
 dehydrogenase/reductase (SDR family) member 12
 94
 0.76
chr5_159214342_159214493 0.19 ADRA1B
 adrenoceptor alpha 1B
 129373
 0.05
chr11_118691288_118691439 0.19 ENSG00000201535
 .
 15356
 0.12
chr7_80928308_80928745 0.19 AC005008.2
 Uncharacterized protein
 111420
 0.08
chr4_18023348_18023557 0.19 LCORL
 ligand dependent nuclear receptor corepressor-like
 31
 0.99
chr6_169475368_169475519 0.19 XXyac-YX65C7_A.2
137906
 0.05
chr3_183878422_183878793 0.19 DVL3
 dishevelled segment polarity protein 3
 4044
 0.12
chrX_139847263_139847516 0.19 CDR1
 cerebellar degeneration-related protein 1, 34kDa
 19334
 0.22
chr1_65400046_65400380 0.19 JAK1
 Janus kinase 1
 31974
 0.2
chr7_100815791_100816003 0.19 NAT16
 N-acetyltransferase 16 (GCN5-related, putative)
 6620
 0.1
chr1_247495331_247495594 0.19 ZNF496
 zinc finger protein 496
 417
 0.84
chr6_168558891_168559173 0.19 FRMD1
 FERM domain containing 1
 76795
 0.11
chr16_89368321_89368642 0.18 AC137932.5
4217
 0.15
chr3_169490145_169490517 0.18 MYNN
 myoneurin
 288
 0.79
chr19_35581704_35581880 0.18 AC020907.1
 Uncharacterized protein
 15081
 0.09
chr7_116732017_116732168 0.18 ST7-AS2
 ST7 antisense RNA 2
 1258
 0.49
chr3_184078420_184078571 0.18 CLCN2
 chloride channel, voltage-sensitive 2
 895
 0.31
chr9_137437911_137438062 0.18 COL5A1
 collagen, type V, alpha 1
 95634
 0.07
chr17_33307453_33307681 0.18 LIG3
 ligase III, DNA, ATP-dependent
 2
 0.9
chr4_48492552_48492703 0.18 ZAR1
 zygote arrest 1
 358
 0.88
chr14_73357781_73357932 0.18 DPF3
 D4, zinc and double PHD fingers, family 3
 2940
 0.24
chr10_100993963_100995023 0.18 HPSE2
 heparanase 2
 1066
 0.66
chr7_129194061_129194212 0.18 SMKR1
 small lysine-rich protein 1
 51503
 0.12
chr6_43970266_43970484 0.17 RP5-1120P11.1
1011
 0.46
chr18_52969288_52969439 0.17 TCF4
 transcription factor 4
 494
 0.88
chr15_34788505_34788693 0.17 ENSG00000221065
 .
 31973
 0.15
chr17_38599985_38600404 0.17 IGFBP4
 insulin-like growth factor binding protein 4
 481
 0.74
chr17_18061433_18061699 0.17 MYO15A
 myosin XVA
 56
 0.96
chr15_77713527_77713880 0.17 HMG20A
 high mobility group 20A
 350
 0.83
chr11_3077193_3077344 0.17 CARS
 cysteinyl-tRNA synthetase
 1364
 0.33
chr4_3306467_3306618 0.17 RGS12
 regulator of G-protein signaling 12
 4220
 0.28
chr6_18122528_18122892 0.17 NHLRC1
 NHL repeat containing E3 ubiquitin protein ligase 1
 141
 0.96
chr12_49318526_49318771 0.17 FKBP11
 FK506 binding protein 11, 19 kDa
 102
 0.91
chr9_19493377_19493724 0.17 RP11-363E7.4
40343
 0.16
chr12_120755596_120755815 0.17 ENSG00000252659
 .
 4561
 0.12
chr2_198243514_198243752 0.17 SF3B1
 splicing factor 3b, subunit 1, 155kDa
 20119
 0.14
chr7_100200956_100201118 0.17 PCOLCE-AS1
 PCOLCE antisense RNA 1
 379
 0.65
chr6_39760880_39761039 0.17 DAAM2
 dishevelled associated activator of morphogenesis 2
 165
 0.97
chr17_66379730_66379881 0.16 ENSG00000207561
 .
 40884
 0.14
chr2_217497534_217497685 0.16 IGFBP2
 insulin-like growth factor binding protein 2, 36kDa
 58
 0.97
chrX_55187773_55187985 0.16 FAM104B
 family with sequence similarity 104, member B
 136
 0.96
chr7_23145115_23145340 0.16 KLHL7
 kelch-like family member 7
 126
 0.97
chr15_96877570_96877721 0.16 ENSG00000222651
 .
 1155
 0.34
chr12_12447841_12447992 0.16 ENSG00000207010
 .
 5653
 0.19
chr17_29887977_29888214 0.16 ENSG00000207614
 .
 1080
 0.35
chr11_63774609_63774760 0.16 OTUB1
 OTU domain, ubiquitin aldehyde binding 1
 20370
 0.1
chr16_88450130_88450579 0.16 ZNF469
 zinc finger protein 469
 43525
 0.15
chr8_70668894_70669045 0.16 RP11-102F4.2
43344
 0.14
chr11_3043840_3044115 0.16 CARS-AS1
 CARS antisense RNA 1
 6647
 0.13
chr19_47447845_47447996 0.16 ENSG00000252071
 .
 3626
 0.22
chr13_34361275_34361581 0.16 RFC3
 replication factor C (activator 1) 3, 38kDa
 30758
 0.21
chr9_103494116_103494267 0.16 ENSG00000200966
 .
 150530
 0.04
chr17_38603034_38603205 0.16 IGFBP4
 insulin-like growth factor binding protein 4
 3406
 0.18
chrX_17394886_17395095 0.16 NHS
 Nance-Horan syndrome (congenital cataracts and dental anomalies)
 1447
 0.46
chr6_7672816_7672976 0.16 BMP6
 bone morphogenetic protein 6
 54134
 0.14
chr3_37493102_37493470 0.16 ITGA9
 integrin, alpha 9
 320
 0.92
chr5_179518071_179518222 0.16 RNF130
 ring finger protein 130
 19028
 0.19
chr19_51227387_51227538 0.15 CLEC11A
 C-type lectin domain family 11, member A
 682
 0.53
chr3_178789075_178789341 0.15 ZMAT3
 zinc finger, matrin-type 3
 146
 0.96
chr14_99848474_99848625 0.15 ENSG00000216173
 .
 19921
 0.19
chr22_28174315_28174484 0.15 MN1
 meningioma (disrupted in balanced translocation) 1
 23087
 0.23
chr6_52422559_52422710 0.15 TRAM2
 translocation associated membrane protein 2
 19079
 0.23
chr17_1081882_1082496 0.15 ABR
 active BCR-related
 889
 0.58
chr11_94502592_94502995 0.15 AMOTL1
 angiomotin like 1
 1256
 0.53
chr1_2231502_2231862 0.15 RP4-713A8.1
26450
 0.11
chr6_137144069_137144462 0.15 PEX7
 peroxisomal biogenesis factor 7
 542
 0.78
chr9_126110255_126110406 0.15 CRB2
 crumbs homolog 2 (Drosophila)
 8119
 0.24
chr7_101579659_101580126 0.15 CTB-181H17.1
23504
 0.22
chr1_28919066_28919537 0.15 RAB42
 RAB42, member RAS oncogene family
 589
 0.62
chr19_41193747_41193898 0.15 NUMBL
 numb homolog (Drosophila)-like
 1675
 0.25
chr6_52437991_52438235 0.15 TRAM2
 translocation associated membrane protein 2
 3600
 0.31
chr22_36902639_36903091 0.14 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
 204
 0.92
chr17_80008374_80008525 0.14 GPS1
 G protein pathway suppressor 1
 375
 0.59
chr21_36935983_36936169 0.14 ENSG00000211590
 .
 156937
 0.04
chr1_244014741_244014953 0.14 AKT3
 v-akt murine thymoma viral oncogene homolog 3
 466
 0.87
chr19_45826969_45827349 0.14 CKM
 creatine kinase, muscle
 924
 0.44
chr2_242626487_242626967 0.14 DTYMK
 deoxythymidylate kinase (thymidylate kinase)
 321
 0.79
chr12_110010896_110011058 0.14 MVK
 mevalonate kinase
 83
 0.79
chr10_74114795_74115085 0.14 DNAJB12
 DnaJ (Hsp40) homolog, subfamily B, member 12
 33
 0.98
chr2_232328586_232328818 0.14 NCL
 nucleolin
 189
 0.89
chr12_109901272_109901510 0.14 KCTD10
 potassium channel tetramerization domain containing 10
 3191
 0.21
chr12_133613669_133614058 0.14 ZNF84
 zinc finger protein 84
 15
 0.97
chr15_90645383_90645632 0.14 IDH2
 isocitrate dehydrogenase 2 (NADP+), mitochondrial
 193
 0.92
chr6_110720825_110721164 0.14 DDO
 D-aspartate oxidase
 15771
 0.18
chr1_57890417_57890605 0.14 DAB1
 Dab, reelin signal transducer, homolog 1 (Drosophila)
 782
 0.79
chr17_18537909_18538132 0.14 TBC1D28
 TBC1 domain family, member 28
 7717
 0.13
chr1_202896403_202896578 0.14 KLHL12
 kelch-like family member 12
 100
 0.95
chr3_39190203_39190389 0.14 CSRNP1
 cysteine-serine-rich nuclear protein 1
 4770
 0.2
chr19_41111211_41111409 0.14 ENSG00000266164
 .
 1645
 0.28
chr16_70148022_70148173 0.14 PDPR
 pyruvate dehydrogenase phosphatase regulatory subunit
 178
 0.94
chr16_28985699_28985940 0.14 SPNS1
 spinster homolog 1 (Drosophila)
 177
 0.87
chr6_136871727_136872192 0.13 MAP7
 microtubule-associated protein 7
 2
 0.67
chr3_49940383_49940534 0.13 MST1R
 macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
 584
 0.48
chrX_52964541_52964769 0.13 FAM156A
 family with sequence similarity 156, member A
 20874
 0.17
chr9_82278752_82279150 0.13 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 11443
 0.33
chr3_148709208_148709359 0.13 GYG1
 glycogenin 1
 16
 0.98
chr3_9958820_9959089 0.13 IL17RC
 interleukin 17 receptor C
 46
 0.93
chr12_65959878_65960118 0.13 MSRB3
 methionine sulfoxide reductase B3
 239343
 0.02
chr6_161664088_161664497 0.13 AGPAT4
 1-acylglycerol-3-phosphate O-acyltransferase 4
 30759
 0.25
chr18_59537327_59537518 0.13 RNF152
 ring finger protein 152
 23570
 0.27
chrX_17395110_17395408 0.13 NHS
 Nance-Horan syndrome (congenital cataracts and dental anomalies)
 1716
 0.4
chr6_31802720_31802923 0.13 C6orf48
 chromosome 6 open reading frame 48
 112
 0.61
chr19_44007928_44008284 0.13 PHLDB3
 pleckstrin homology-like domain, family B, member 3
 460
 0.71
chr17_20812306_20812457 0.13 RP11-344E13.3
11977
 0.13
chr1_150254993_150255622 0.13 C1orf51
 chromosome 1 open reading frame 51
 78
 0.94
chr18_158238_158410 0.13 USP14
 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
 59
 0.98
chr18_53398919_53399070 0.13 TCF4
 transcription factor 4
 66976
 0.14
chr2_242823909_242824060 0.13 AC131097.3
115
 0.94
chr21_47038314_47038465 0.13 PCBP3
 poly(rC) binding protein 3
 25219
 0.21
chr13_97992448_97992599 0.13 MBNL2
 muscleblind-like splicing regulator 2
 16527
 0.22
chr3_192289269_192289452 0.13 ENSG00000238902
 .
 37459
 0.17
chr1_68297532_68297957 0.13 GNG12-AS1
 GNG12 antisense RNA 1
 242
 0.9
chrX_292077_292313 0.13 LINC00685
 long intergenic non-protein coding RNA 685
 10470
 0.23
chr3_61668665_61668816 0.13 ENSG00000252420
 .
 56163
 0.17
chr10_76994278_76994482 0.13 COMTD1
 catechol-O-methyltransferase domain containing 1
 1303
 0.47
chr9_46168304_46168455 0.13 ENSG00000238413
 .
 26704
 0.23
chr5_91833_92077 0.13 PLEKHG4B
 pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
 48418
 0.13
chr14_76446267_76446546 0.13 TGFB3
 transforming growth factor, beta 3
 930
 0.62
chr8_80681214_80681467 0.13 HEY1
 hes-related family bHLH transcription factor with YRPW motif 1
 1242
 0.56
chr19_35939103_35939363 0.13 FFAR2
 free fatty acid receptor 2
 30
 0.96
chr16_839466_839674 0.13 CHTF18
 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
 257
 0.75
chr8_1771644_1772131 0.13 ARHGEF10
 Rho guanine nucleotide exchange factor (GEF) 10
 255
 0.93
chr14_26994857_26995008 0.13 RP11-483C6.1
68791
 0.11
chr3_72091935_72092086 0.12 ENSG00000239250
 .
 215682
 0.02
chr1_214397865_214398571 0.12 SMYD2
 SET and MYND domain containing 2
 56358
 0.16
chr20_25208343_25208494 0.12 AL035252.1
 HCG2018895; Uncharacterized protein
 1048
 0.47
chrX_129039705_129039949 0.12 UTP14A
 UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
 270
 0.92
chr3_42697942_42698093 0.12 RP4-613B23.1
2137
 0.17
chrX_56790465_56790994 0.12 ENSG00000204272
 .
 35037
 0.23
chr11_79718516_79718667 0.12 ENSG00000221551
 .
 315168
 0.01
chr7_5637609_5637772 0.12 FSCN1
 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
 3373
 0.21
chr6_133562382_133562833 0.12 EYA4
 eyes absent homolog 4 (Drosophila)
 51
 0.99
chr19_2783530_2783806 0.12 SGTA
 small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
 299
 0.8
chr7_150065813_150066064 0.12 REPIN1
 replication initiator 1
 22
 0.52
chr17_49230988_49231211 0.12 NME1
 NME/NM23 nucleoside diphosphate kinase 1
 73
 0.37
chr10_126359460_126359611 0.12 FAM53B-AS1
 FAM53B antisense RNA 1
 32659
 0.18
chr3_30691423_30691574 0.12 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 43405
 0.18
chr8_143782547_143782698 0.12 LY6K
 lymphocyte antigen 6 complex, locus K
 732
 0.49
chr22_30641304_30641455 0.12 RP1-102K2.8
605
 0.52
chr8_122652196_122652655 0.12 HAS2-AS1
 HAS2 antisense RNA 1
 283
 0.88
chr8_102121369_102121647 0.12 ENSG00000202360
 .
 28679
 0.21
chr5_141257083_141257234 0.12 PCDH1
 protocadherin 1
 796
 0.64
chr5_118733448_118733675 0.12 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 41831
 0.13
chr4_20256302_20256578 0.12 SLIT2
 slit homolog 2 (Drosophila)
 103
 0.98

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0090266 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.2 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.2 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.0 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.3 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.1 GO:0034227 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.0 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.2 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.1 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0046051 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0005536 glucose binding(GO:0005536)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism