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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for CUX1

Z-value: 1.42

Motif logo

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Transcription factors associated with CUX1

Gene Symbol Gene ID Gene Info
CUX1
ENSG00000257923.5 cut like homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_101460259_101460698CUX14040.873916-0.771.5e-02Click!
chr7_101459490_101459645CUX12660.931579-0.761.7e-02Click!
chr7_101459208_101459407CUX160.982319-0.752.0e-02Click!
chr7_101397584_101398512CUX1609110.121573-0.618.3e-02Click!
chr7_101457714_101458422CUX18910.644913-0.589.8e-02Click!

Activity of the CUX1 motif across conditions

Conditions sorted by the z-value of the CUX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chrX_69674453_69675874 0.58 DLG3
 discs, large homolog 3 (Drosophila)
 217
 0.75
chrX_39964334_39965624 0.34 BCOR
 BCL6 corepressor
 8323
 0.32
chr1_161038546_161039545 0.33 ARHGAP30
 Rho GTPase activating protein 30
 411
 0.65
chr9_93577957_93578337 0.32 SYK
 spleen tyrosine kinase
 11623
 0.32
chr13_113597266_113598290 0.32 MCF2L
 MCF.2 cell line derived transforming sequence-like
 24979
 0.15
chr22_29601932_29602692 0.30 EMID1
 EMI domain containing 1
 400
 0.8
chr7_67384045_67384316 0.27 ENSG00000265600
 .
 562513
 0.0
chr8_68304896_68305241 0.27 ARFGEF1
 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
 49156
 0.18
chr5_1110808_1112337 0.26 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
 578
 0.75
chr1_245951382_245951568 0.26 RP11-522M21.3
111695
 0.07
chr16_28506747_28507012 0.25 CLN3
 ceroid-lipofuscinosis, neuronal 3
 24
 0.94
chr9_92275535_92275686 0.25 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 55657
 0.16
chr6_170604225_170605407 0.24 FAM120B
 family with sequence similarity 120B
 407
 0.83
chr10_101088892_101089952 0.24 CNNM1
 cyclin M1
 266
 0.95
chr1_22345507_22345745 0.23 ENSG00000201273
 .
 8148
 0.1
chr11_14665333_14666638 0.23 PDE3B
 phosphodiesterase 3B, cGMP-inhibited
 608
 0.56
chr2_238607001_238607152 0.23 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
 6094
 0.25
chr6_54711000_54712080 0.22 FAM83B
 family with sequence similarity 83, member B
 29
 0.98
chr20_52492319_52492470 0.22 AC005220.3
64305
 0.13
chr13_33589965_33590391 0.22 KL
 klotho
 29
 0.98
chr3_150887706_150887956 0.21 ENSG00000199994
 .
 18055
 0.16
chr17_57408824_57410302 0.20 YPEL2
 yippee-like 2 (Drosophila)
 500
 0.78
chr17_21279729_21280949 0.20 KCNJ12
 potassium inwardly-rectifying channel, subfamily J, member 12
 830
 0.69
chr13_113237033_113237219 0.20 TUBGCP3
 tubulin, gamma complex associated protein 3
 5313
 0.28
chr16_89766857_89768141 0.20 SPATA2L
 spermatogenesis associated 2-like
 549
 0.59
chr21_47344013_47344164 0.20 PRED62
 Uncharacterized protein
 8389
 0.2
chr20_39122695_39122846 0.20 ENSG00000252434
 .
 77255
 0.12
chr1_192130669_192130880 0.19 RGS18
 regulator of G-protein signaling 18
 3187
 0.4
chr12_14731074_14731371 0.19 PLBD1
 phospholipase B domain containing 1
 9939
 0.15
chr2_16615403_16615554 0.19 AC104623.2
88966
 0.1
chr2_103042024_103042175 0.19 IL18RAP
 interleukin 18 receptor accessory protein
 5953
 0.15
chr22_31613545_31613991 0.19 ENSG00000199695
 .
 5071
 0.12
chr6_20404021_20405019 0.19 E2F3
 E2F transcription factor 3
 486
 0.77
chr10_106085822_106086336 0.19 ITPRIP
 inositol 1,4,5-trisphosphate receptor interacting protein
 2603
 0.2
chr20_3293982_3294133 0.19 C20orf194
 chromosome 20 open reading frame 194
 27551
 0.12
chr4_38602953_38603104 0.19 RP11-617D20.1
23168
 0.2
chr12_12735789_12735940 0.18 DUSP16
 dual specificity phosphatase 16
 20547
 0.19
chrX_152599728_152600567 0.18 ZNF275
 zinc finger protein 275
 534
 0.76
chr15_94841194_94841722 0.18 MCTP2
 multiple C2 domains, transmembrane 2
 28
 0.99
chr2_74691535_74692741 0.18 MOGS
 mannosyl-oligosaccharide glucosidase
 351
 0.67
chr22_30577376_30577527 0.18 RP3-438O4.4
25647
 0.13
chr9_21964953_21966022 0.18 C9orf53
 chromosome 9 open reading frame 53
 1650
 0.31
chr22_41843038_41844299 0.18 TOB2
 transducer of ERBB2, 2
 641
 0.64
chr4_97275136_97275287 0.18 ENSG00000201640
 .
 5022
 0.36
chr22_17577263_17577414 0.18 IL17RA
 interleukin 17 receptor A
 11489
 0.15
chr16_127905_128996 0.18 MPG
 N-methylpurine-DNA glycosylase
 194
 0.87
chr3_112686974_112687125 0.18 CD200R1
 CD200 receptor 1
 6710
 0.17
chr17_55889172_55889323 0.18 ENSG00000222976
 .
 22437
 0.16
chr8_97352110_97352386 0.18 ENSG00000199732
 .
 30698
 0.17
chr1_108492584_108492735 0.17 VAV3-AS1
 VAV3 antisense RNA 1
 14406
 0.21
chrX_67913478_67914353 0.17 STARD8
 StAR-related lipid transfer (START) domain containing 8
 422
 0.91
chr1_204962096_204962247 0.17 NFASC
 neurofascin
 4141
 0.24
chr7_64461546_64461954 0.17 ERV3-1
 endogenous retrovirus group 3, member 1
 5281
 0.17
chr17_72740646_72740797 0.17 ENSG00000264624
 .
 4031
 0.11
chr19_54714075_54714317 0.17 RPS9
 ribosomal protein S9
 9168
 0.07
chr12_107153685_107153836 0.17 RIC8B
 RIC8 guanine nucleotide exchange factor B
 14613
 0.17
chr1_181068882_181069172 0.17 IER5
 immediate early response 5
 11389
 0.23
chr13_27335081_27335232 0.17 GPR12
 G protein-coupled receptor 12
 234
 0.96
chr2_149894818_149895436 0.17 LYPD6B
 LY6/PLAUR domain containing 6B
 105
 0.98
chr3_50395480_50396917 0.17 TMEM115
 transmembrane protein 115
 843
 0.33
chr19_13906290_13907522 0.17 ZSWIM4
 zinc finger, SWIM-type containing 4
 632
 0.39
chr17_41790734_41791669 0.17 ENSG00000215964
 .
 34367
 0.11
chr3_71829345_71829567 0.17 PROK2
 prokineticin 2
 4756
 0.22
chr19_32836514_32837661 0.17 ZNF507
 zinc finger protein 507
 462
 0.81
chr3_46504181_46504332 0.17 LTF
 lactotransferrin
 905
 0.54
chr2_9142725_9143476 0.16 MBOAT2
 membrane bound O-acyltransferase domain containing 2
 694
 0.76
chr16_72910024_72910217 0.16 ENSG00000251868
 .
 54229
 0.12
chr2_63276750_63277690 0.16 OTX1
 orthodenticle homeobox 1
 28
 0.97
chr12_42862786_42862937 0.16 RP11-328C8.4
9693
 0.15
chr6_42504782_42504933 0.16 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
 26943
 0.17
chr22_45604259_45604410 0.16 KIAA0930
 KIAA0930
 2604
 0.24
chr7_105898290_105898441 0.16 NAMPT
 nicotinamide phosphoribosyltransferase
 27002
 0.18
chr11_65627927_65628967 0.16 MUS81
 MUS81 structure-specific endonuclease subunit
 89
 0.82
chr6_159476816_159477190 0.16 TAGAP
 T-cell activation RhoGTPase activating protein
 10819
 0.2
chr9_94184266_94184417 0.16 NFIL3
 nuclear factor, interleukin 3 regulated
 1803
 0.49
chr5_180631418_180632621 0.16 TRIM7
 tripartite motif containing 7
 153
 0.85
chr15_92400679_92401101 0.16 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 3539
 0.31
chr8_71128828_71128979 0.16 NCOA2
 nuclear receptor coactivator 2
 28707
 0.22
chr21_47789248_47789399 0.16 PCNT
 pericentrin
 45287
 0.1
chr2_220251514_220252585 0.16 DNPEP
 aspartyl aminopeptidase
 19
 0.94
chr19_54783961_54784112 0.16 LILRB2
 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
 317
 0.74
chr19_38494188_38494741 0.16 CTC-244M17.1
39971
 0.13
chr2_31541639_31542033 0.16 EHD3
 EH-domain containing 3
 84633
 0.08
chr6_1624554_1625514 0.16 FOXC1
 forkhead box C1
 14353
 0.29
chrX_68384708_68385863 0.16 PJA1
 praja ring finger 1, E3 ubiquitin protein ligase
 5
 0.99
chrX_12929174_12929325 0.16 TLR8-AS1
 TLR8 antisense RNA 1
 2797
 0.26
chr3_101797946_101798097 0.16 ZPLD1
 zona pellucida-like domain containing 1
 20067
 0.26
chr15_50356488_50356639 0.16 ATP8B4
 ATPase, class I, type 8B, member 4
 16979
 0.23
chr12_92755876_92756027 0.16 RP11-693J15.4
59356
 0.12
chr10_14920855_14921866 0.16 SUV39H2
 suppressor of variegation 3-9 homolog 2 (Drosophila)
 439
 0.82
chr1_167572076_167572227 0.16 RCSD1
 RCSD domain containing 1
 27179
 0.16
chr2_113885287_113885446 0.16 IL1RN
 interleukin 1 receptor antagonist
 228
 0.91
chr11_67807279_67808325 0.16 TCIRG1
 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
 1229
 0.3
chr3_4793449_4793634 0.16 ENSG00000239126
 .
 126845
 0.05
chr3_32344642_32344793 0.16 ENSG00000207857
 .
 43497
 0.14
chr2_43188289_43188440 0.16 ENSG00000207087
 .
 130268
 0.05
chr18_74843262_74844680 0.16 MBP
 myelin basic protein
 331
 0.94
chr10_70883973_70885223 0.15 VPS26A
 vacuolar protein sorting 26 homolog A (S. pombe)
 595
 0.74
chr2_197076357_197076527 0.15 ENSG00000239161
 .
 3604
 0.24
chr15_83540435_83540586 0.15 HOMER2
 homer homolog 2 (Drosophila)
 7499
 0.17
chr19_2494417_2495562 0.15 ENSG00000252962
 .
 8150
 0.15
chr2_217180593_217180957 0.15 AC069155.1
12727
 0.18
chr3_15578534_15578685 0.15 COLQ
 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
 15351
 0.14
chr9_117568588_117568807 0.15 TNFSF15
 tumor necrosis factor (ligand) superfamily, member 15
 291
 0.92
chr9_124016304_124016710 0.15 GSN
 gelsolin
 13831
 0.14
chr9_33523659_33524999 0.15 ANKRD18B
 ankyrin repeat domain 18B
 63
 0.97
chr19_45754620_45755932 0.15 MARK4
 MAP/microtubule affinity-regulating kinase 4
 726
 0.57
chr14_21249278_21249626 0.15 RNASE6
 ribonuclease, RNase A family, k6
 242
 0.86
chrX_13751428_13751579 0.15 TRAPPC2
 trafficking protein particle complex 2
 1172
 0.37
chr5_10607962_10608181 0.15 ANKRD33B-AS1
 ANKRD33B antisense RNA 1
 20266
 0.2
chr16_1991808_1991959 0.15 MSRB1
 methionine sulfoxide reductase B1
 1241
 0.18
chrX_13955774_13956778 0.15 GPM6B
 glycoprotein M6B
 258
 0.95
chr2_28811248_28811399 0.15 PLB1
 phospholipase B1
 13463
 0.23
chr6_156338794_156338945 0.15 ENSG00000221456
 .
 70938
 0.14
chr12_48212353_48213256 0.15 HDAC7
 histone deacetylase 7
 241
 0.91
chr12_92424206_92424357 0.15 C12orf79
 chromosome 12 open reading frame 79
 106516
 0.07
chr2_190444828_190446170 0.15 SLC40A1
 solute carrier family 40 (iron-regulated transporter), member 1
 114
 0.98
chr5_142193879_142194030 0.15 ARHGAP26
 Rho GTPase activating protein 26
 41672
 0.17
chr18_53006641_53006980 0.15 TCF4
 transcription factor 4
 12418
 0.28
chr8_142105945_142106235 0.15 DENND3
 DENN/MADD domain containing 3
 21287
 0.19
chr2_238395971_238396408 0.15 MLPH
 melanophilin
 270
 0.92
chr22_31631160_31631361 0.15 ENSG00000202019
 .
 5102
 0.12
chr2_108443697_108444171 0.15 RGPD4
 RANBP2-like and GRIP domain containing 4
 541
 0.87
chr2_155001115_155001266 0.15 ENSG00000266512
 .
 1530
 0.54
chr22_17598033_17598230 0.15 CECR6
 cat eye syndrome chromosome region, candidate 6
 4012
 0.17
chr2_60774113_60774264 0.15 BCL11A
 B-cell CLL/lymphoma 11A (zinc finger protein)
 6352
 0.26
chr1_16769456_16769607 0.15 NECAP2
 NECAP endocytosis associated 2
 2300
 0.23
chr11_126188773_126189028 0.15 RP11-712L6.5
 Uncharacterized protein
 14687
 0.1
chr1_45274565_45275349 0.15 BTBD19
 BTB (POZ) domain containing 19
 762
 0.37
chr20_48301152_48301303 0.15 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
 29188
 0.16
chr1_234658507_234658658 0.15 TARBP1
 TAR (HIV-1) RNA binding protein 1
 43733
 0.14
chr12_11926562_11926926 0.15 ETV6
 ets variant 6
 21309
 0.26
chr12_121340609_121341729 0.15 SPPL3
 signal peptide peptidase like 3
 4
 0.98
chr4_26263054_26263205 0.15 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 11100
 0.31
chr7_150131124_150131275 0.15 GIMAP8
 GTPase, IMAP family member 8
 16519
 0.14
chr7_105318075_105318226 0.15 ATXN7L1
 ataxin 7-like 1
 1459
 0.53
chr15_50359492_50359643 0.15 ATP8B4
 ATPase, class I, type 8B, member 4
 19983
 0.22
chr9_5493967_5494181 0.15 PDCD1LG2
 programmed cell death 1 ligand 2
 16471
 0.2
chr2_208091726_208091877 0.15 AC007879.5
27175
 0.18
chr2_30454378_30455881 0.14 LBH
 limb bud and heart development
 83
 0.98
chr3_51691608_51691759 0.14 TEX264
 testis expressed 264
 5026
 0.17
chr13_88325876_88326239 0.14 SLITRK5
 SLIT and NTRK-like family, member 5
 559
 0.85
chr16_29471210_29471476 0.14 SULT1A4
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
 133
 0.91
chr12_117536177_117536841 0.14 TESC
 tescalcin
 742
 0.76
chr19_14551433_14551660 0.14 PKN1
 protein kinase N1
 474
 0.7
chr16_53124890_53125176 0.14 CHD9
 chromodomain helicase DNA binding protein 9
 8039
 0.24
chr8_68296421_68296572 0.14 ARFGEF1
 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
 40584
 0.21
chr3_131753321_131753947 0.14 CPNE4
 copine IV
 210
 0.96
chr17_40811022_40812282 0.14 TUBG2
 tubulin, gamma 2
 329
 0.76
chr19_38736860_38737011 0.14 SPINT2
 serine peptidase inhibitor, Kunitz type, 2
 2260
 0.16
chr8_77320453_77320604 0.14 ENSG00000222231
 .
 142561
 0.05
chr4_11652870_11653079 0.14 HS3ST1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
 221585
 0.02
chr11_118023255_118024161 0.14 SCN4B
 sodium channel, voltage-gated, type IV, beta subunit
 105
 0.96
chr12_132475297_132475448 0.14 ENSG00000271905
 .
 10948
 0.16
chr21_45527300_45528294 0.14 PWP2
 PWP2 periodic tryptophan protein homolog (yeast)
 543
 0.75
chr20_3189609_3190930 0.14 ITPA
 inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
 98
 0.95
chr1_158218516_158218667 0.14 CD1A
 CD1a molecule
 5336
 0.22
chr2_219124080_219124231 0.14 GPBAR1
 G protein-coupled bile acid receptor 1
 64
 0.94
chr5_63461313_63462499 0.14 RNF180
 ring finger protein 180
 83
 0.99
chr15_48604529_48604680 0.14 ENSG00000202542
 .
 13264
 0.17
chr2_198167617_198167768 0.14 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 449
 0.8
chr17_76879212_76879961 0.14 TIMP2
 TIMP metallopeptidase inhibitor 2
 9354
 0.14
chr22_30053890_30054041 0.14 NF2
 neurofibromin 2 (merlin)
 53977
 0.08
chr1_207244470_207244690 0.14 PFKFB2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
 6231
 0.14
chr7_148844568_148845756 0.14 ZNF398
 zinc finger protein 398
 57
 0.97
chr17_2699734_2700214 0.14 RAP1GAP2
 RAP1 GTPase activating protein 2
 198
 0.94
chr1_170633420_170634117 0.14 PRRX1
 paired related homeobox 1
 690
 0.8
chr10_22894404_22894761 0.14 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
 13940
 0.29
chr4_38802207_38802358 0.14 TLR1
 toll-like receptor 1
 3715
 0.19
chr11_75490080_75490231 0.14 CTD-2530H12.2
3206
 0.13
chr6_88875424_88876640 0.14 CNR1
 cannabinoid receptor 1 (brain)
 46
 0.99
chr14_89290449_89291591 0.14 TTC8
 tetratricopeptide repeat domain 8
 9
 0.97
chr10_99090099_99090250 0.14 RP11-452K12.4
4147
 0.13
chr7_31851375_31851526 0.14 ENSG00000223070
 .
 17588
 0.29
chr5_15704054_15704205 0.14 FBXL7
 F-box and leucine-rich repeat protein 7
 88038
 0.09
chr6_53109316_53109571 0.14 ENSG00000206908
 .
 25384
 0.15
chr4_113626760_113627887 0.14 ENSG00000202536
 .
 49750
 0.09
chr1_28571461_28571612 0.14 RP5-1092A3.4
3572
 0.14
chr18_53007051_53007202 0.14 TCF4
 transcription factor 4
 12102
 0.28
chr17_61106096_61106247 0.14 TANC2
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
 19250
 0.23
chr19_36207272_36208543 0.14 KMT2B
 Histone-lysine N-methyltransferase 2B
 1014
 0.26
chr9_88137440_88138079 0.14 AGTPBP1
 ATP/GTP binding protein 1
 158442
 0.04
chr17_77019963_77021139 0.14 C1QTNF1
 C1q and tumor necrosis factor related protein 1
 208
 0.91
chr16_67282110_67283381 0.13 SLC9A5
 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
 108
 0.89
chr7_148237370_148237521 0.13 C7orf33
 chromosome 7 open reading frame 33
 50212
 0.15
chr11_67041225_67041376 0.13 ADRBK1
 adrenergic, beta, receptor kinase 1
 7348
 0.12
chr3_47031255_47031478 0.13 NBEAL2
 neurobeachin-like 2
 5445
 0.19
chr20_4807814_4807965 0.13 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 3598
 0.24
chr14_102320200_102320351 0.13 CTD-2017C7.1
14407
 0.16
chr20_47414178_47414329 0.13 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 30167
 0.21
chr15_100017896_100018047 0.13 MEF2A
 myocyte enhancer factor 2A
 601
 0.77
chr19_47610168_47610319 0.13 SAE1
 SUMO1 activating enzyme subunit 1
 6288
 0.16
chr10_81026521_81026806 0.13 ZMIZ1
 zinc finger, MIZ-type containing 1
 39312
 0.18
chr1_23860213_23860364 0.13 E2F2
 E2F transcription factor 2
 2576
 0.26
chr11_119953003_119953290 0.13 TRIM29
 tripartite motif containing 29
 38462
 0.18
chr14_24803093_24804202 0.13 ADCY4
 adenylate cyclase 4
 306
 0.72
chr8_27262752_27262933 0.13 PTK2B
 protein tyrosine kinase 2 beta
 7873
 0.23
chr19_14223228_14223791 0.13 PRKACA
 protein kinase, cAMP-dependent, catalytic, alpha
 1491
 0.22
chr6_20267392_20267543 0.13 MBOAT1
 membrane bound O-acyltransferase domain containing 1
 54797
 0.13
chr2_11483078_11484442 0.13 ROCK2
 Rho-associated, coiled-coil containing protein kinase 2
 951
 0.65

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.2 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.2 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:2001280 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0009111 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0048342 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.0 GO:0060510 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0090398 cellular senescence(GO:0090398)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0015669 gas transport(GO:0015669)
0.0 0.0 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.0 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.0 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.0 GO:0001787 natural killer cell proliferation(GO:0001787) regulation of natural killer cell proliferation(GO:0032817)
0.0 0.0 GO:0051299 centrosome separation(GO:0051299)
0.0 0.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:0060004 reflex(GO:0060004)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:1901978 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0051318 G1 phase(GO:0051318)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.0 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100)
0.0 0.0 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.1 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0007140 male meiosis(GO:0007140)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.2 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.0 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0033558 protein deacetylase activity(GO:0033558)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.0 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.0 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network