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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for CUX2

Z-value: 2.96

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Transcription factors associated with CUX2

Gene Symbol	Gene ID	Gene Info
CUX2 Ensembl NCBI GeneCards UniProt	ENSG00000111249.9	cut like homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_111472240_111472468	CUX2	526	0.832954	0.55	1.2e-01	Click!
chr12_111473052_111473203	CUX2	1299	0.529942	0.55	1.3e-01	Click!
chr12_111471309_111471548	CUX2	400	0.888834	0.53	1.4e-01	Click!
chr12_111471913_111472064	CUX2	160	0.967122	0.49	1.8e-01	Click!
chr12_111549682_111549895	CUX2	12538	0.235336	-0.31	4.2e-01	Click!

Activity of the CUX2 motif across conditions

Conditions sorted by the z-value of the CUX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_207094320_207094619	1.64	FAIM3	Fas apoptotic inhibitory molecule 3	743	0.59
chr4_36244695_36244948	1.59	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	740	0.5
chr10_6627562_6627792	1.56	PRKCQ	protein kinase C, theta	5414	0.34
chr14_61793878_61794206	1.54	PRKCH	protein kinase C, eta	411	0.85
chr2_68963054_68963510	1.51	ARHGAP25	Rho GTPase activating protein 25	1268	0.56
chr21_40139305_40139870	1.49	ETS2	v-ets avian erythroblastosis virus E26 oncogene homolog 2	37644	0.21
chr7_50348888_50349341	1.47	IKZF1	IKAROS family zinc finger 1 (Ikaros)	796	0.76
chr12_118796743_118797337	1.47	TAOK3	TAO kinase 3	69	0.98
chr13_46755773_46755938	1.38	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	604	0.7
chr9_4285477_4285628	1.33	GLIS3	GLIS family zinc finger 3	12944	0.21
chr13_74806763_74806914	1.32	ENSG00000206617	.	56513	0.16
chr3_152002678_152002963	1.26	MBNL1	muscleblind-like splicing regulator 1	14374	0.21
chr21_15917471_15917848	1.23	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	1003	0.63
chrX_12990488_12990859	1.22	TMSB4X	thymosin beta 4, X-linked	2554	0.33
chr13_84126063_84126363	1.20	ENSG00000222791	.	253911	0.02
chr1_220527416_220527567	1.18	AC096644.1	Uncharacterized protein	80532	0.09
chrX_78400540_78401325	1.18	GPR174	G protein-coupled receptor 174	25537	0.27
chr20_31099035_31099434	1.13	C20orf112	chromosome 20 open reading frame 112	24	0.98
chr20_49128549_49128700	1.12	PTPN1	protein tyrosine phosphatase, non-receptor type 1	1704	0.35
chr12_9822873_9823085	1.10	CLEC2D	C-type lectin domain family 2, member D	630	0.62
chr6_159464766_159465080	1.10	TAGAP	T-cell activation RhoGTPase activating protein	1127	0.51
chr17_30816627_30816809	1.09	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	1904	0.22
chr22_40298890_40299260	1.08	GRAP2	GRB2-related adaptor protein 2	1962	0.3
chr4_40209794_40209945	1.08	RHOH	ras homolog family member H	7905	0.22
chr1_55678186_55678720	1.07	USP24	ubiquitin specific peptidase 24	2309	0.34
chr12_54891959_54892179	1.07	NCKAP1L	NCK-associated protein 1-like	499	0.73
chr3_56832611_56832838	1.07	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	3253	0.36
chr1_198492691_198493057	1.07	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	16930	0.28
chr5_28058907_28059058	1.06	ENSG00000221721	.	72590	0.14
chr1_198609469_198609717	1.04	PTPRC	protein tyrosine phosphatase, receptor type, C	1301	0.54
chr17_33859992_33860143	1.04	SLFN12L	schlafen family member 12-like	4813	0.13
chr21_15917916_15918619	1.02	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	395	0.89
chr4_109084692_109084886	1.02	LEF1	lymphoid enhancer-binding factor 1	2668	0.31
chr14_22997550_22997780	1.01	TRAJ15	T cell receptor alpha joining 15	915	0.43
chr14_22966248_22966484	1.01	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	10195	0.1
chr12_8101164_8101417	1.00	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	12419	0.15
chr2_202127394_202127951	1.00	CASP8	caspase 8, apoptosis-related cysteine peptidase	993	0.56
chr3_107845159_107845310	1.00	CD47	CD47 molecule	35362	0.21
chr12_57077777_57078354	0.98	PTGES3	prostaglandin E synthase 3 (cytosolic)	3881	0.14
chr3_187520878_187521148	0.98	BCL6	B-cell CLL/lymphoma 6	57498	0.14
chr8_29936071_29936255	0.98	TMEM66	transmembrane protein 66	3777	0.18
chr9_4865980_4866131	0.97	AL158147.2	HCG2011465; Uncharacterized protein	6795	0.16
chrX_78202733_78203002	0.97	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	1949	0.5
chr14_92331424_92331867	0.96	TC2N	tandem C2 domains, nuclear	2228	0.32
chr3_163274827_163274978	0.96	ENSG00000265090	.	40627	0.21
chr1_110046824_110047046	0.96	AMIGO1	adhesion molecule with Ig-like domain 1	5369	0.11
chr8_134086469_134086645	0.95	SLA	Src-like-adaptor	13954	0.23
chr14_71353925_71354621	0.95	PCNX	pecanex homolog (Drosophila)	19849	0.26
chrX_78620829_78620980	0.95	ITM2A	integral membrane protein 2A	1952	0.51
chr6_43082789_43082940	0.95	PTK7	protein tyrosine kinase 7	15465	0.11
chr8_29955696_29955905	0.94	LEPROTL1	leptin receptor overlapping transcript-like 1	2635	0.22
chr13_41589998_41590808	0.94	ELF1	E74-like factor 1 (ets domain transcription factor)	3047	0.26
chr22_40299734_40299885	0.93	GRAP2	GRB2-related adaptor protein 2	2696	0.25
chr18_77162823_77163056	0.93	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	2547	0.35
chr6_128239524_128239756	0.93	THEMIS	thymocyte selection associated	45	0.99
chr13_30510013_30510639	0.93	LINC00572	long intergenic non-protein coding RNA 572	9538	0.3
chr5_130603053_130603363	0.92	CDC42SE2	CDC42 small effector 2	3415	0.35
chr13_71667523_71667674	0.92	ENSG00000202433	.	634002	0.0
chr14_71466281_71466432	0.91	PCNX	pecanex homolog (Drosophila)	13392	0.29
chr9_123687593_123687825	0.91	TRAF1	TNF receptor-associated factor 1	3338	0.27
chr1_98816414_98816565	0.91	ENSG00000221777	.	22452	0.29
chr14_23011759_23011910	0.91	TRAJ15	T cell receptor alpha joining 15	13254	0.1
chr4_108642323_108642546	0.90	PAPSS1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	826	0.74
chr2_204572488_204572658	0.90	CD28	CD28 molecule	1157	0.58
chr4_111437212_111437424	0.88	RP11-380D23.1		3343	0.3
chr14_99732558_99733007	0.88	AL109767.1		3497	0.26
chr13_41556565_41556847	0.88	ELF1	E74-like factor 1 (ets domain transcription factor)	288	0.92
chr6_128221625_128221781	0.87	THEMIS	thymocyte selection associated	400	0.91
chr15_81590989_81591168	0.87	IL16	interleukin 16	679	0.71
chr6_125401116_125401267	0.87	RNF217	ring finger protein 217	31833	0.2
chr1_1477179_1477330	0.87	TMEM240	transmembrane protein 240	1421	0.26
chr4_143321082_143321233	0.87	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	31255	0.26
chr1_101784802_101784953	0.87	RP4-575N6.5		76163	0.09
chr11_104941226_104941560	0.86	CARD16	caspase recruitment domain family, member 16	25290	0.15
chrX_30594869_30596024	0.85	CXorf21	chromosome X open reading frame 21	515	0.84
chr11_88068800_88069370	0.85	CTSC	cathepsin C	1816	0.49
chr8_38216839_38216990	0.85	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	21425	0.11
chr1_6087488_6087778	0.85	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	276	0.91
chr17_29639732_29640055	0.84	EVI2B	ecotropic viral integration site 2B	1209	0.36
chr8_124282051_124282202	0.84	ZHX1-C8ORF76	ZHX1-C8ORF76 readthrough	2499	0.16
chr2_64441014_64441273	0.84	AC074289.1		7034	0.28
chr1_24513976_24514201	0.83	IFNLR1	interferon, lambda receptor 1	337	0.87
chr1_198613830_198613981	0.83	PTPRC	protein tyrosine phosphatase, receptor type, C	5613	0.26
chr21_29050610_29050761	0.83	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	711853	0.0
chr7_104908860_104909472	0.83	SRPK2	SRSF protein kinase 2	296	0.92
chr3_32996346_32996497	0.82	CCR4	chemokine (C-C motif) receptor 4	3355	0.33
chr12_25207113_25207806	0.81	LRMP	lymphoid-restricted membrane protein	1785	0.37
chr4_40202894_40203061	0.81	RHOH	ras homolog family member H	1013	0.59
chr5_72334540_72334691	0.81	ENSG00000200833	.	61285	0.11
chr2_194347562_194347833	0.81	NA	NA	> 10⁶	NA
chr5_58055562_58056142	0.80	RP11-479O16.1		24754	0.24
chr7_142430441_142430617	0.80	PRSS1	protease, serine, 1 (trypsin 1)	26790	0.17
chr8_71287137_71287766	0.80	ENSG00000207036	.	17869	0.21
chr4_109084210_109084462	0.80	LEF1	lymphoid enhancer-binding factor 1	3121	0.29
chr21_32553343_32553494	0.80	TIAM1	T-cell lymphoma invasion and metastasis 1	50879	0.17
chr2_45794731_45794926	0.79	SRBD1	S1 RNA binding domain 1	326	0.88
chr14_61799597_61799891	0.79	PRKCH	protein kinase C, eta	6113	0.21
chr3_32993381_32993532	0.79	CCR4	chemokine (C-C motif) receptor 4	390	0.9
chr6_24951057_24951285	0.78	FAM65B	family with sequence similarity 65, member B	14983	0.22
chr17_27137805_27137956	0.78	FAM222B	family with sequence similarity 222, member B	1362	0.23
chr7_7287223_7287567	0.78	C1GALT1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1	13444	0.24
chr21_20465237_20465388	0.78	ENSG00000212609	.	252153	0.02
chr14_102278905_102279056	0.78	CTD-2017C7.2		2322	0.22
chr6_154568354_154568864	0.78	IPCEF1	interaction protein for cytohesin exchange factors 1	53	0.99
chr1_198610198_198610371	0.77	PTPRC	protein tyrosine phosphatase, receptor type, C	1992	0.4
chr14_23038615_23038766	0.77	AE000662.93		12734	0.1
chr17_74750226_74750377	0.77	ENSG00000200257	.	1307	0.26
chr12_42492275_42492426	0.77	ENSG00000222884	.	18787	0.22
chr5_45697193_45697344	0.77	HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1	1015	0.72
chr6_159235914_159236507	0.77	EZR-AS1	EZR antisense RNA 1	2833	0.23
chrX_78401406_78401924	0.77	GPR174	G protein-coupled receptor 174	24804	0.27
chr2_202098878_202099103	0.77	CASP8	caspase 8, apoptosis-related cysteine peptidase	761	0.65
chr6_26403092_26403274	0.77	BTN3A1	butyrophilin, subfamily 3, member A1	660	0.54
chr12_71721523_71721674	0.77	LGR5	leucine-rich repeat containing G protein-coupled receptor 5	111952	0.06
chr1_39681454_39681741	0.76	RP11-416A14.1		9413	0.17
chr6_6386490_6386781	0.76	F13A1	coagulation factor XIII, A1 polypeptide	65389	0.13
chr3_111260963_111261300	0.76	CD96	CD96 molecule	134	0.97
chr12_111471309_111471548	0.75	CUX2	cut-like homeobox 2	400	0.89
chr14_55799126_55799413	0.75	RP11-665C16.5		6950	0.25
chrX_70328307_70328586	0.75	IL2RG	interleukin 2 receptor, gamma	672	0.51
chr10_15873436_15873587	0.75	FAM188A	family with sequence similarity 188, member A	5787	0.29
chr7_150413396_150413547	0.75	GIMAP1	GTPase, IMAP family member 1	174	0.94
chr15_59981781_59982063	0.75	BNIP2	BCL2/adenovirus E1B 19kDa interacting protein 2	189	0.9
chr3_112693608_112694254	0.74	CD200R1	CD200 receptor 1	6	0.97
chr1_32721190_32721341	0.74	LCK	lymphocyte-specific protein tyrosine kinase	4390	0.1
chr10_7793124_7793275	0.74	KIN	KIN, antigenic determinant of recA protein homolog (mouse)	36745	0.14
chr1_205425124_205425391	0.74	LEMD1	LEM domain containing 1	6198	0.17
chr7_21472009_21472160	0.74	SP4	Sp4 transcription factor	4423	0.22
chr14_99729127_99729416	0.74	AL109767.1		14	0.98
chr2_69002223_69002932	0.74	ARHGAP25	Rho GTPase activating protein 25	505	0.84
chrX_31453419_31453570	0.74	ENSG00000252903	.	87185	0.1
chr10_105670292_105670878	0.74	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1	6842	0.18
chr14_53208430_53208600	0.74	STYX	serine/threonine/tyrosine interacting protein	11615	0.15
chrX_12990257_12990408	0.73	TMSB4X	thymosin beta 4, X-linked	2895	0.31
chr6_25405502_25405752	0.73	ENSG00000253017	.	2496	0.27
chr13_49136021_49136172	0.73	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	28727	0.23
chr13_99857558_99857709	0.73	ENSG00000201793	.	329	0.88
chr7_100140182_100140395	0.73	AGFG2	ArfGAP with FG repeats 2	3406	0.11
chr2_139740607_139740758	0.72	ENSG00000222826	.	119217	0.07
chr18_29601411_29601562	0.72	RNF125	ring finger protein 125, E3 ubiquitin protein ligase	3151	0.21
chr2_214004488_214004639	0.72	IKZF2	IKAROS family zinc finger 2 (Helios)	8790	0.3
chr13_105637174_105637325	0.72	DAOA	D-amino acid oxidase activator	481343	0.01
chr12_26399329_26399480	0.72	RP11-283G6.5		25351	0.18
chr6_106547367_106547905	0.72	RP1-134E15.3		379	0.74
chr20_57234804_57234955	0.71	STX16	syntaxin 16	7697	0.17
chr3_73031631_73031782	0.71	PPP4R2	protein phosphatase 4, regulatory subunit 2	14230	0.18
chr2_213983567_213983718	0.71	IKZF2	IKAROS family zinc finger 2 (Helios)	29711	0.24
chr15_96817385_96817602	0.71	NR2F2-AS1	NR2F2 antisense RNA 1	1732	0.37
chr14_22980644_22980795	0.71	TRAJ15	T cell receptor alpha joining 15	17861	0.09
chr12_117535875_117536067	0.70	TESC	tescalcin	1280	0.57
chr3_151973155_151973306	0.70	MBNL1	muscleblind-like splicing regulator 1	12599	0.22
chrX_57314086_57314237	0.70	FAAH2	fatty acid amide hydrolase 2	1022	0.69
chr16_74634832_74635106	0.70	GLG1	golgi glycoprotein 1	6023	0.24
chr3_43430810_43431075	0.70	SNRK-AS1	SNRK antisense RNA 1	37488	0.15
chr15_90735520_90735720	0.70	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	460	0.74
chr9_22668028_22668179	0.70	DMRTA1	DMRT-like family A1	221263	0.02
chr4_90408760_90409167	0.70	RP11-115D19.1		63544	0.15
chr13_74807691_74807851	0.69	ENSG00000206617	.	55580	0.16
chr11_82828119_82828301	0.69	PCF11	PCF11 cleavage and polyadenylation factor subunit	39820	0.12
chr14_22980147_22980432	0.69	TRAJ15	T cell receptor alpha joining 15	18291	0.09
chr17_29645805_29646348	0.69	CTD-2370N5.3		227	0.88
chrX_154493044_154493313	0.69	RAB39B	RAB39B, member RAS oncogene family	696	0.67
chr11_98660793_98660944	0.68	CNTN5	contactin 5	231003	0.02
chr12_47610316_47610761	0.68	PCED1B	PC-esterase domain containing 1B	157	0.96
chr17_76670239_76670390	0.68	ENSG00000252391	.	22565	0.18
chr2_102974215_102974435	0.67	IL18R1	interleukin 18 receptor 1	1936	0.32
chr2_113065761_113065912	0.67	ZC3H6	zinc finger CCCH-type containing 6	32658	0.16
chr6_90903910_90904061	0.67	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	102476	0.07
chr5_74965499_74965780	0.67	ENSG00000207333	.	39785	0.14
chr12_4384723_4384874	0.67	CCND2	cyclin D2	432	0.41
chr5_118674167_118674322	0.67	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	5374	0.23
chr21_42493311_42493462	0.67	LINC00323	long intergenic non-protein coding RNA 323	25964	0.16
chr6_106809590_106809741	0.67	RP11-404H14.1		2073	0.31
chr14_22992275_22992426	0.67	TRAJ15	T cell receptor alpha joining 15	6230	0.12
chr11_118176160_118176414	0.67	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	673	0.59
chr14_58711962_58712794	0.66	PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	756	0.54
chr16_68503734_68504345	0.66	ENSG00000199263	.	4528	0.18
chr1_160614614_160614765	0.66	SLAMF1	signaling lymphocytic activation molecule family member 1	2122	0.27
chr5_119820967_119821118	0.66	PRR16	proline rich 16	19716	0.29
chr10_33234705_33234856	0.66	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	9601	0.29
chr2_109230989_109231140	0.66	LIMS1	LIM and senescent cell antigen-like domains 1	6658	0.25
chr3_28133741_28133892	0.66	CMC1	C-x(9)-C motif containing 1	149270	0.04
chr6_37484799_37485050	0.66	CCDC167	coiled-coil domain containing 167	17226	0.19
chr11_67478742_67478899	0.66	ENSG00000266451	.	23259	0.12
chr8_10981801_10982129	0.66	AF131215.3		1609	0.27
chr4_68410033_68410229	0.66	CENPC	centromere protein C	1193	0.53
chrX_33573585_33573736	0.66	DMD	dystrophin	216102	0.02
chr1_192776419_192777001	0.65	RGS2	regulator of G-protein signaling 2, 24kDa	1461	0.52
chr4_109086470_109087224	0.65	LEF1	lymphoid enhancer-binding factor 1	610	0.72
chr6_48087052_48087203	0.65	PTCHD4	patched domain containing 4	50702	0.19
chr7_150414678_150414897	0.65	GIMAP1	GTPase, IMAP family member 1	1142	0.45
chr1_198734901_198735052	0.65	ENSG00000207975	.	93135	0.08
chr3_183271904_183272141	0.65	KLHL6	kelch-like family member 6	1455	0.38
chr16_84766778_84766973	0.64	USP10	ubiquitin specific peptidase 10	33229	0.16
chr6_27058062_27058213	0.64	ENSG00000222800	.	19622	0.13
chr12_40076492_40076709	0.64	C12orf40	chromosome 12 open reading frame 40	56615	0.14
chr22_45933014_45933165	0.64	FBLN1	fibulin 1	18426	0.2
chr14_23005213_23005364	0.64	TRAJ15	T cell receptor alpha joining 15	6708	0.11
chr6_82470488_82470639	0.64	ENSG00000206886	.	3178	0.26
chr9_84437486_84437637	0.64	ENSG00000263404	.	16565	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.6	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.5	1.4	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.4	1.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.4	1.9	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.4	1.5	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.3	1.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.3	2.9	GO:0043383	negative T cell selection(GO:0043383)
0.3	0.9	GO:0000103	sulfate assimilation(GO:0000103)
0.3	2.7	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3	1.5	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.3	1.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.3	2.2	GO:0002507	tolerance induction(GO:0002507)
0.3	1.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.2	0.7	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	1.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.2	0.7	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.2	1.7	GO:0006491	N-glycan processing(GO:0006491)
0.2	0.2	GO:0072160	nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.2	0.5	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.2	0.5	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.2	0.5	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.2	0.3	GO:0072224	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.2	0.5	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.2	0.5	GO:0010040	response to iron(II) ion(GO:0010040)
0.2	0.8	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.3	GO:0001821	histamine secretion(GO:0001821)
0.1	0.4	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.4	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.3	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	1.1	GO:0015671	oxygen transport(GO:0015671)
0.1	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.1	0.4	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.4	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.1	0.5	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.3	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1	0.2	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.6	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.1	0.2	GO:0045350	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.2	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1	0.3	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1	0.3	GO:0072577	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1	0.3	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.4	GO:0046645	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1	0.5	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.4	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.1	0.2	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	1.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.3	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.1	0.4	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.3	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	0.3	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.8	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.2	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.8	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	2.1	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1	0.4	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1	0.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1	0.2	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.1	0.8	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1	0.2	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.2	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.6	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.4	GO:0046902	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.1	0.2	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.3	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.1	0.5	GO:0002420	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.5	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.1	GO:1901186	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.1	4.0	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.1	0.2	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	1.3	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.1	0.3	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.3	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	0.6	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1	0.3	GO:0016266	O-glycan processing(GO:0016266)
0.1	0.2	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.1	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1	0.2	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.2	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.1	0.2	GO:0043276	anoikis(GO:0043276)
0.1	0.2	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.1	0.3	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.1	0.2	GO:0007343	egg activation(GO:0007343)
0.1	1.9	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.1	0.3	GO:0042346	positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.1	0.1	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.1	0.1	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.2	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.1	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.7	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.2	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.2	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1	1.0	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1	0.2	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.3	GO:0060134	prepulse inhibition(GO:0060134)
0.1	1.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	0.4	GO:0045176	apical protein localization(GO:0045176)
0.1	1.2	GO:0032873	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.1	0.2	GO:0032025	response to cobalt ion(GO:0032025)
0.1	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.3	GO:0060017	parathyroid gland development(GO:0060017)
0.1	0.5	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.4	GO:0006670	sphingosine metabolic process(GO:0006670)
0.1	0.2	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	0.6	GO:0030224	monocyte differentiation(GO:0030224)
0.1	0.2	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.2	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	0.2	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.8	GO:0043484	regulation of RNA splicing(GO:0043484)
0.1	0.2	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	0.2	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.4	GO:0017004	cytochrome complex assembly(GO:0017004)
0.0	0.3	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.2	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.7	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0051135	regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.4	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.4	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0098732	protein deacylation(GO:0035601) macromolecule deacylation(GO:0098732)
0.0	0.5	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.0	0.3	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.1	GO:0042832	response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0	0.3	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	1.0	GO:0006997	nucleus organization(GO:0006997)
0.0	0.3	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	1.0	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.3	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.2	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.2	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.5	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	1.5	GO:0016571	histone methylation(GO:0016571)
0.0	0.0	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.5	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.2	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.2	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	1.6	GO:0006968	cellular defense response(GO:0006968)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:2000380	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.5	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.4	GO:0045730	respiratory burst(GO:0045730)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.8	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.0	GO:0046958	nonassociative learning(GO:0046958)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.1	GO:0048670	collateral sprouting(GO:0048668) regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.8	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.2	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0045409	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.7	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.2	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.2	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.0	GO:0051132	NK T cell activation(GO:0051132)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.3	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.0	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.2	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0010823	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	1.4	GO:0072413	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.4	GO:0051693	actin filament capping(GO:0051693)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.4	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0009180	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.8	GO:0033572	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.2	GO:0060045	positive regulation of cardiac muscle tissue growth(GO:0055023) positive regulation of cardiac muscle tissue development(GO:0055025) positive regulation of cardiac muscle cell proliferation(GO:0060045) positive regulation of heart growth(GO:0060421)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0060253	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) regulation of glial cell proliferation(GO:0060251) negative regulation of glial cell proliferation(GO:0060253)
0.0	0.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0046666	retinal cell programmed cell death(GO:0046666)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.4	GO:0051225	spindle assembly(GO:0051225)
0.0	0.2	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.1	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.2	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.1	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.6	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.1	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.8	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.1	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.2	GO:0043543	protein acylation(GO:0043543)
0.0	5.5	GO:0016568	chromatin modification(GO:0016568)
0.0	1.8	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	0.0	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.4	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.4	GO:0019079	viral genome replication(GO:0019079)
0.0	0.1	GO:0045616	regulation of keratinocyte differentiation(GO:0045616)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.3	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	1.3	GO:0000236	mitotic prometaphase(GO:0000236)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.3	GO:0046949	fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.5	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0050746	regulation of lipoprotein metabolic process(GO:0050746)
0.0	0.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.7	GO:0006818	hydrogen transport(GO:0006818)
0.0	0.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.3	GO:1900181	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.1	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0061097	regulation of protein tyrosine kinase activity(GO:0061097)
0.0	0.2	GO:0043526	obsolete neuroprotection(GO:0043526)
0.0	0.5	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0	0.0	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.1	GO:0007099	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0014824	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.6	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.4	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	2.4	GO:0043087	regulation of GTPase activity(GO:0043087)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.2	GO:1901800	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.5	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.4	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.0	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.3	GO:0006885	regulation of pH(GO:0006885)
0.0	0.0	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.0	GO:0010561	negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0002228	natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.2	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0070646	protein modification by small protein removal(GO:0070646)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0031054	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) pre-miRNA processing(GO:0031054)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.2	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.1	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.0	GO:0018216	peptidyl-arginine methylation(GO:0018216) peptidyl-arginine N-methylation(GO:0035246)
0.0	0.0	GO:0006907	pinocytosis(GO:0006907)
0.0	0.1	GO:0008542	visual learning(GO:0008542)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0000050	urea cycle(GO:0000050)
0.0	0.8	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	0.1	GO:0033363	secretory granule organization(GO:0033363)
0.0	0.2	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.1	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.0	1.2	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.3	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.2	GO:0000084	mitotic S phase(GO:0000084)
0.0	0.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.2	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.6	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.0	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.2	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:1903008	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) organelle disassembly(GO:1903008)
0.0	0.0	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.2	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0044743	intracellular protein transmembrane import(GO:0044743)
0.0	0.0	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.0	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0090037	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.0	GO:0043096	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.0	GO:0090502	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA 5'-end processing(GO:0000966) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0006282	regulation of DNA repair(GO:0006282)
0.0	0.4	GO:0006909	phagocytosis(GO:0006909)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.1	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0050684	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.0	GO:2000258	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.7	GO:0009615	response to virus(GO:0009615)
0.0	0.0	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.0	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.0	GO:0033151	V(D)J recombination(GO:0033151)
0.0	0.2	GO:2001057	nitric oxide metabolic process(GO:0046209) reactive nitrogen species metabolic process(GO:2001057)
0.0	0.0	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.0	0.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.2	GO:0006402	mRNA catabolic process(GO:0006402)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0007506	gonadal mesoderm development(GO:0007506)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.2	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.0	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.2	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.0	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.0	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0009304	tRNA transcription(GO:0009304)
0.0	0.0	GO:0003417	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0	0.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.1	GO:0006401	RNA catabolic process(GO:0006401)
0.0	0.1	GO:0030317	sperm motility(GO:0030317)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.5	GO:0001891	phagocytic cup(GO:0001891)
0.3	1.6	GO:0031264	death-inducing signaling complex(GO:0031264)
0.3	1.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.2	0.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	0.7	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	0.5	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.2	0.5	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	0.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.8	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	0.5	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.6	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.9	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	0.7	GO:0070688	MLL5-L complex(GO:0070688)
0.1	1.1	GO:0001772	immunological synapse(GO:0001772)
0.1	0.8	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.9	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.3	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.8	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1	0.3	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.5	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	0.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.4	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.2	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.6	GO:0090533	cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.2	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.6	GO:0000242	pericentriolar material(GO:0000242)
0.1	0.8	GO:0005844	polysome(GO:0005844)
0.1	0.2	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.7	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.5	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.3	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.6	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.6	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.0	0.9	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.3	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.5	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.4	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.3	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.5	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	2.1	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.7	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	1.4	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	2.0	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.8	GO:0016592	mediator complex(GO:0016592)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.0	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.5	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.9	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	1.4	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.9	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.8	GO:0031091	platelet alpha granule(GO:0031091)
0.0	0.4	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0070603	SWI/SNF superfamily-type complex(GO:0070603)
0.0	0.7	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	1.5	GO:0000785	chromatin(GO:0000785)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	1.2	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.4	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.3	GO:0009295	nucleoid(GO:0009295)
0.0	0.1	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.0	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.0	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.0	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.2	GO:0005871	kinesin complex(GO:0005871)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3	1.9	GO:0001784	phosphotyrosine binding(GO:0001784)
0.2	0.9	GO:0030284	estrogen receptor activity(GO:0030284)
0.2	0.7	GO:0035184	histone threonine kinase activity(GO:0035184)
0.2	4.5	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2	1.9	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.2	2.3	GO:0004697	protein kinase C activity(GO:0004697)
0.2	0.9	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2	0.5	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.2	0.5	GO:0042608	T cell receptor binding(GO:0042608)
0.2	0.5	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.2	0.5	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1	1.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.5	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.5	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	2.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.4	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.4	GO:0051380	norepinephrine binding(GO:0051380)
0.1	0.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.3	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.3	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	1.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.9	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.4	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.4	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.2	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.8	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.5	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	1.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	0.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.3	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.3	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	0.3	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.4	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.2	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.6	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1	0.3	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.1	1.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.3	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.5	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.3	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.5	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.4	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.7	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1	0.4	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.3	GO:0015925	galactosidase activity(GO:0015925)
0.1	1.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	0.5	GO:0017136	histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H3-K9 specific)(GO:0032129) protein deacetylase activity(GO:0033558) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent protein deacetylase activity(GO:0034979) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1	0.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.3	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.1	GO:0033265	choline binding(GO:0033265)
0.1	0.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.5	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	3.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.4	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.1	0.4	GO:0005521	lamin binding(GO:0005521)
0.1	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.2	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.2	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	3.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.8	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.4	GO:0032452	histone demethylase activity(GO:0032452)
0.1	0.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	0.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.2	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	0.2	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.3	GO:0015288	porin activity(GO:0015288)
0.1	0.5	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1	0.3	GO:0009922	fatty acid elongase activity(GO:0009922)
0.1	0.3	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	0.2	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	1.3	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.4	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.3	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.4	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.2	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	1.0	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.2	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.5	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.2	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	1.5	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	1.2	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.4	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.4	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	1.1	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.0	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.6	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.7	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.4	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.5	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.2	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.6	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.6	GO:0030552	cAMP binding(GO:0030552)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.8	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	1.0	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.2	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.0	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.7	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.2	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	1.0	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.2	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.0	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.5	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	2.7	GO:0004386	helicase activity(GO:0004386)
0.0	1.0	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.6	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.8	GO:0042393	histone binding(GO:0042393)
0.0	0.7	GO:0003954	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0008556	sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.8	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.3	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.0	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.4	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.2	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.0	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	1.1	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	3.1	GO:0016563	obsolete transcription activator activity(GO:0016563)
0.0	0.5	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.0	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.3	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.0	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.0	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0060229	lipase activator activity(GO:0060229) lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.0	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	1.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.2	GO:0000049	tRNA binding(GO:0000049)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.0	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	3.8	GO:0005525	GTP binding(GO:0005525)
0.0	0.2	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.4	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.0	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.0	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0005537	mannose binding(GO:0005537)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.0	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.0	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.3	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.0	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.9	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	4.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	8.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	5.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	1.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.4	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	0.9	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.8	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	1.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	2.8	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.3	PID ENDOTHELIN PATHWAY	Endothelins
0.1	0.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.1	0.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	2.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	0.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	0.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	1.6	PID ARF6 PATHWAY	Arf6 signaling events
0.1	0.8	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.4	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.7	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.5	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.1	PID MYC PATHWAY	C-MYC pathway
0.0	0.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.4	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.3	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.4	PID ATR PATHWAY	ATR signaling pathway
0.0	0.2	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.1	PID TNF PATHWAY	TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	2.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2	2.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	2.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.8	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.0	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	1.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	0.5	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	3.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	0.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.8	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	1.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	0.9	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	1.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	1.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	2.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.8	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	2.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.8	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.7	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	2.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.5	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
0.0	0.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.6	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	1.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	2.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.8	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.7	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.0	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.0	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.1	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade

Results for CUX2

Z-value: 2.96

Motif logo

Transcription factors associated with CUX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the CUX2 motif across conditions

Conditions sorted by the z-value of the CUX2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: