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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for DLX1_HOXA3_BARX2

Z-value: 1.02

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Transcription factors associated with DLX1_HOXA3_BARX2

Gene Symbol	Gene ID	Gene Info
DLX1 Ensembl NCBI GeneCards UniProt	ENSG00000144355.10	distal-less homeobox 1
HOXA3 Ensembl NCBI GeneCards UniProt	ENSG00000105997.18	homeobox A3
BARX2 Ensembl NCBI GeneCards UniProt	ENSG00000043039.5	BARX homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_129245088_129245270	BARX2	656	0.816313	0.56	1.2e-01	Click!
chr11_129243062_129243656	BARX2	2476	0.412366	0.45	2.3e-01	Click!
chr11_129242275_129242426	BARX2	3485	0.356232	-0.41	2.7e-01	Click!
chr11_129244074_129244550	BARX2	1523	0.542584	0.32	4.0e-01	Click!
chr11_129242593_129242759	BARX2	3159	0.369655	0.32	4.0e-01	Click!
chr2_172951434_172951585	DLX1	1245	0.496892	0.77	1.5e-02	Click!
chr2_172948607_172948758	DLX1	786	0.674454	0.77	1.6e-02	Click!
chr2_172958009_172958160	DLX1	7820	0.207962	0.70	3.5e-02	Click!
chr2_172947668_172947819	DLX1	1725	0.393210	0.63	6.9e-02	Click!
chr2_172917249_172917400	DLX1	32144	0.164637	0.52	1.5e-01	Click!
chr7_27150712_27150972	HOXA3	2622	0.104312	0.75	2.0e-02	Click!
chr7_27152154_27152305	HOXA3	1235	0.194179	0.64	6.4e-02	Click!
chr7_27150237_27150691	HOXA3	3000	0.096485	0.62	7.5e-02	Click!
chr7_27176258_27176409	HOXA3	3492	0.077544	0.61	7.9e-02	Click!
chr7_27151802_27151953	HOXA3	1587	0.153829	0.57	1.1e-01	Click!

Activity of the DLX1_HOXA3_BARX2 motif across conditions

Conditions sorted by the z-value of the DLX1_HOXA3_BARX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_87036535_87037613	1.60	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chr7_129933276_129933885	1.58	CPA4	carboxypeptidase A4	461	0.76
chr7_93550787_93551002	1.27	GNG11	guanine nucleotide binding protein (G protein), gamma 11	117	0.96
chr21_17909068_17909746	1.11	ENSG00000207638	.	2002	0.33
chr7_95107815_95108198	1.06	ASB4	ankyrin repeat and SOCS box containing 4	7207	0.2
chr8_116675050_116675578	1.03	TRPS1	trichorhinophalangeal syndrome I	1409	0.6
chr3_105657205_105657471	1.02	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	68942	0.15
chr13_24146066_24146217	0.98	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1338	0.59
chr4_77506894_77507309	0.95	ENSG00000265314	.	10397	0.17
chr9_18474095_18474958	0.91	ADAMTSL1	ADAMTS-like 1	295	0.95
chr3_33318777_33319866	0.89	FBXL2	F-box and leucine-rich repeat protein 2	353	0.91
chr7_17720120_17720505	0.89	SNX13	sorting nexin 13	259779	0.02
chr11_131780111_131780399	0.87	NTM	neurotrimin	642	0.77
chr8_93114852_93115389	0.86	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	334	0.94
chr6_116833589_116833880	0.84	TRAPPC3L	trafficking protein particle complex 3-like	228	0.83
chr13_73081776_73081993	0.83	ENSG00000251715	.	47145	0.15
chr18_53089837_53090372	0.83	TCF4	transcription factor 4	361	0.89
chr6_126135984_126136135	0.79	NCOA7	nuclear receptor coactivator 7	305	0.89
chr20_50384318_50384901	0.79	ATP9A	ATPase, class II, type 9A	258	0.94
chr7_93552303_93552503	0.78	GNG11	guanine nucleotide binding protein (G protein), gamma 11	1392	0.38
chr12_66286178_66286489	0.76	RP11-366L20.2	Uncharacterized protein	10386	0.18
chr1_196577911_196578299	0.76	KCNT2	potassium channel, subfamily T, member 2	250	0.94
chr18_53090404_53090609	0.76	TCF4	transcription factor 4	763	0.7
chr4_57975072_57975270	0.75	IGFBP7-AS1	IGFBP7 antisense RNA 1	757	0.52
chr6_85823864_85824548	0.75	NT5E	5'-nucleotidase, ecto (CD73)	335603	0.01
chr17_19998529_19998923	0.74	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1	279	0.92
chr11_12849556_12849989	0.73	RP11-47J17.3		4558	0.23
chr12_66220556_66220804	0.73	HMGA2	high mobility group AT-hook 2	1777	0.39
chr12_56917781_56918152	0.73	RBMS2	RNA binding motif, single stranded interacting protein 2	2183	0.23
chr12_78336292_78336638	0.72	NAV3	neuron navigator 3	23591	0.28
chr12_66221036_66221187	0.69	HMGA2	high mobility group AT-hook 2	2208	0.34
chr15_37179413_37179956	0.69	ENSG00000212511	.	34843	0.22
chr4_134070427_134071051	0.68	PCDH10	protocadherin 10	269	0.96
chr1_68697735_68698156	0.68	WLS	wntless Wnt ligand secretion mediator	18	0.98
chr3_112356169_112356393	0.68	CCDC80	coiled-coil domain containing 80	663	0.77
chr6_19691587_19692480	0.68	ENSG00000200957	.	49273	0.18
chr8_38855409_38855789	0.67	ADAM9	ADAM metallopeptidase domain 9	1094	0.34
chr1_84107245_84107582	0.67	ENSG00000223231	.	152147	0.04
chr10_60273912_60274168	0.66	BICC1	bicaudal C homolog 1 (Drosophila)	1140	0.65
chr13_38172411_38172686	0.66	POSTN	periostin, osteoblast specific factor	315	0.95
chr3_79066759_79066910	0.65	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	860	0.75
chr2_207998546_207999225	0.65	KLF7	Kruppel-like factor 7 (ubiquitous)	24	0.98
chr15_96878465_96878729	0.65	ENSG00000222651	.	2107	0.24
chr8_37350646_37351319	0.64	RP11-150O12.6		23557	0.24
chr1_87799796_87800719	0.64	LMO4	LIM domain only 4	2906	0.4
chr2_151340168_151340387	0.63	RND3	Rho family GTPase 3	1619	0.57
chr16_54968513_54968925	0.63	IRX5	iroquois homeobox 5	2735	0.43
chr20_45946936_45948261	0.63	AL031666.2	HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852	352	0.82
chr4_41215270_41215769	0.61	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	956	0.59
chr5_66311217_66311678	0.61	MAST4	microtubule associated serine/threonine kinase family member 4	10964	0.24
chr15_99794226_99794420	0.61	LRRC28	leucine rich repeat containing 28	2307	0.22
chr5_88080560_88081020	0.61	MEF2C	myocyte enhancer factor 2C	38815	0.18
chr10_6763782_6764322	0.61	PRKCQ	protein kinase C, theta	141789	0.05
chr20_10502111_10502382	0.61	SLX4IP	SLX4 interacting protein	86295	0.09
chr5_174178214_174178699	0.61	ENSG00000266890	.	281	0.94
chr11_111849006_111849202	0.61	DIXDC1	DIX domain containing 1	1071	0.39
chr10_86185479_86185663	0.60	CCSER2	coiled-coil serine-rich protein 2	876	0.74
chr4_157997366_157997978	0.60	GLRB	glycine receptor, beta	117	0.97
chr3_114477857_114478359	0.60	ZBTB20	zinc finger and BTB domain containing 20	10	0.99
chr11_106239153_106239583	0.60	RP11-680E19.1		104326	0.08
chr17_66700653_66700804	0.60	ENSG00000263690	.	61972	0.13
chr18_20612011_20612377	0.59	ENSG00000223023	.	7635	0.17
chr2_38295840_38295991	0.59	RMDN2-AS1	RMDN2 antisense RNA 1	1731	0.34
chr3_110791913_110792064	0.59	PVRL3	poliovirus receptor-related 3	973	0.53
chr5_149867786_149868254	0.59	NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	2163	0.3
chr15_42749459_42749764	0.58	ZNF106	zinc finger protein 106	100	0.96
chr8_57086542_57086822	0.58	PLAG1	pleiomorphic adenoma gene 1	37156	0.12
chr2_58266503_58266768	0.57	VRK2	vaccinia related kinase 2	7094	0.27
chr4_157891142_157892336	0.57	PDGFC	platelet derived growth factor C	316	0.91
chr2_200446222_200446758	0.57	SATB2	SATB homeobox 2	110501	0.07
chr2_66668625_66669005	0.57	AC092669.1		153	0.89
chr4_82413627_82413778	0.56	RASGEF1B	RasGEF domain family, member 1B	20633	0.28
chr4_15471989_15472140	0.56	CC2D2A	coiled-coil and C2 domain containing 2A	427	0.85
chr10_101736542_101736753	0.56	DNMBP	dynamin binding protein	33029	0.15
chr20_43965593_43965922	0.56	SDC4	syndecan 4	11307	0.11
chr6_27060216_27060434	0.56	ENSG00000222800	.	17434	0.13
chr14_29859562_29859789	0.56	ENSG00000257522	.	11813	0.29
chr5_82767889_82768074	0.55	VCAN	versican	237	0.96
chr9_104248314_104249564	0.55	TMEM246	transmembrane protein 246	460	0.79
chr15_88020923_88021173	0.55	ENSG00000207150	.	3528	0.4
chr21_36253539_36254227	0.55	RUNX1	runt-related transcription factor 1	5597	0.33
chr4_108746841_108747185	0.55	SGMS2	sphingomyelin synthase 2	649	0.76
chr9_89952337_89952906	0.55	ENSG00000212421	.	77256	0.11
chr22_36233928_36234199	0.55	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	2202	0.43
chr15_80365541_80365692	0.55	ZFAND6	zinc finger, AN1-type domain 6	684	0.75
chr3_114169976_114170457	0.54	ZBTB20	zinc finger and BTB domain containing 20	3314	0.33
chr15_71054590_71054766	0.54	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	1091	0.55
chr1_39881370_39881756	0.54	MACF1	microtubule-actin crosslinking factor 1	1491	0.39
chr3_61546098_61546562	0.54	PTPRG	protein tyrosine phosphatase, receptor type, G	1255	0.64
chr6_163817634_163818149	0.54	QKI	QKI, KH domain containing, RNA binding	17784	0.29
chr1_162603392_162603656	0.54	DDR2	discoidin domain receptor tyrosine kinase 2	1264	0.48
chr5_58592476_58593460	0.54	PDE4D	phosphodiesterase 4D, cAMP-specific	21023	0.29
chr1_170640402_170640573	0.54	PRRX1	paired related homeobox 1	7409	0.3
chr8_131206424_131206650	0.54	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	13429	0.23
chr1_68214173_68214559	0.54	ENSG00000238778	.	23970	0.19
chr12_89845524_89845923	0.54	POC1B	POC1 centriolar protein B	45311	0.13
chr6_86167890_86168219	0.53	NT5E	5'-nucleotidase, ecto (CD73)	8227	0.28
chr11_121966638_121966789	0.53	ENSG00000207971	.	3839	0.19
chr4_71479096_71479386	0.53	ENAM	enamelin	15220	0.15
chr10_69831641_69832005	0.53	HERC4	HECT and RLD domain containing E3 ubiquitin protein ligase 4	2071	0.33
chr15_99864758_99865035	0.53	AC022819.2	Uncharacterized protein	5068	0.23
chr17_35851874_35852313	0.53	DUSP14	dual specificity phosphatase 14	523	0.79
chr14_101867418_101867569	0.53	ENSG00000258498	.	159266	0.02
chr13_33858125_33858279	0.53	STARD13	StAR-related lipid transfer (START) domain containing 13	1690	0.4
chr4_6887879_6888223	0.52	TBC1D14	TBC1 domain family, member 14	22918	0.18
chr7_27202641_27202952	0.52	HOXA9	homeobox A9	2349	0.09
chr4_124339787_124340099	0.52	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	18820	0.3
chr16_53244996_53245358	0.52	CHD9	chromodomain helicase DNA binding protein 9	2814	0.29
chr10_33620428_33620906	0.52	NRP1	neuropilin 1	2643	0.37
chr8_62625183_62625719	0.52	ASPH	aspartate beta-hydroxylase	1633	0.37
chr8_77599205_77599356	0.51	ZFHX4	zinc finger homeobox 4	3264	0.28
chr7_14028526_14029745	0.51	ETV1	ets variant 1	156	0.97
chr13_76588981_76589230	0.51	ENSG00000243274	.	119962	0.06
chr1_89447034_89447185	0.51	CCBL2	cysteine conjugate-beta lyase 2	11178	0.15
chr2_145210039_145210510	0.51	ZEB2	zinc finger E-box binding homeobox 2	22137	0.25
chr3_79411197_79411348	0.51	ENSG00000265193	.	145765	0.05
chr2_110656312_110656910	0.51	LIMS3	LIM and senescent cell antigen-like domains 3	343	0.93
chr10_115032925_115033406	0.51	ENSG00000238380	.	80019	0.11
chr3_120215962_120216316	0.51	FSTL1	follistatin-like 1	46039	0.16
chr6_26577102_26577344	0.51	ABT1	activator of basal transcription 1	19957	0.15
chr1_153585227_153585451	0.51	S100A16	S100 calcium binding protein A16	220	0.83
chr8_108506884_108507225	0.51	ANGPT1	angiopoietin 1	169	0.98
chr9_79483882_79484033	0.51	PRUNE2	prune homolog 2 (Drosophila)	37044	0.21
chrX_114829080_114829277	0.50	PLS3	plastin 3	1313	0.48
chr3_44063258_44064101	0.50	ENSG00000252980	.	48900	0.17
chr9_22008020_22008450	0.50	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	717	0.61
chr3_174159101_174159924	0.50	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2	735	0.81
chr4_54063057_54063462	0.49	ENSG00000207385	.	68475	0.13
chr5_158524974_158525234	0.49	EBF1	early B-cell factor 1	1597	0.48
chr16_73089798_73090050	0.49	ZFHX3	zinc finger homeobox 3	3673	0.28
chr14_75039149_75039311	0.49	LTBP2	latent transforming growth factor beta binding protein 2	39545	0.13
chr5_107229567_107229740	0.49	ENSG00000251732	.	83323	0.11
chr1_151918063_151918251	0.48	THEM4	thioesterase superfamily member 4	35873	0.1
chr2_109271526_109272143	0.48	LIMS1	LIM and senescent cell antigen-like domains 1	325	0.91
chr2_128492018_128492224	0.48	SFT2D3	SFT2 domain containing 3	33524	0.13
chr2_198540490_198540682	0.48	RFTN2	raftlin family member 2	133	0.96
chr17_42214986_42215221	0.48	ENSG00000212446	.	1746	0.18
chr3_116583114_116583333	0.48	ENSG00000265433	.	14009	0.25
chrX_16825753_16826181	0.48	TXLNG	taxilin gamma	21412	0.16
chr20_56749874_56750278	0.48	C20orf85	chromosome 20 open reading frame 85	24116	0.19
chr18_56244152_56244311	0.48	RP11-126O1.2		19929	0.14
chr7_151297260_151297484	0.48	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	32067	0.18
chr6_28442401_28443147	0.48	ZSCAN23	zinc finger and SCAN domain containing 23	31530	0.13
chr8_77589944_77590318	0.48	ZFHX4	zinc finger homeobox 4	3323	0.29
chr8_48648492_48649280	0.48	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	2762	0.26
chr7_151328064_151328292	0.47	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	1261	0.55
chr6_148829582_148830289	0.47	ENSG00000223322	.	15441	0.29
chr5_111090218_111090459	0.47	NREP	neuronal regeneration related protein	1610	0.42
chr6_165341513_165341675	0.47	C6orf118	chromosome 6 open reading frame 118	380748	0.01
chr7_28726429_28726958	0.47	CREB5	cAMP responsive element binding protein 5	1095	0.68
chr14_53509566_53509717	0.47	RP11-368P15.3		6168	0.27
chr6_27859319_27859470	0.47	HIST1H3J	histone cluster 1, H3j	824	0.31
chr12_120246427_120246712	0.47	CIT	citron (rho-interacting, serine/threonine kinase 21)	5382	0.27
chr6_5471426_5471612	0.47	RP1-232P20.1		13211	0.27
chr3_59101471_59101696	0.47	C3orf67	chromosome 3 open reading frame 67	65773	0.15
chr10_73725086_73725706	0.47	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	1273	0.55
chr6_1613704_1614304	0.46	FOXC1	forkhead box C1	3323	0.37
chr1_79506717_79506893	0.46	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1	34402	0.23
chr15_80840560_80840711	0.46	RP11-379K22.2		14650	0.18
chr11_114167823_114168031	0.46	NNMT	nicotinamide N-methyltransferase	158	0.96
chr5_3597777_3597928	0.46	IRX1	iroquois homeobox 1	1684	0.41
chr19_1361544_1361801	0.46	MUM1	melanoma associated antigen (mutated) 1	5309	0.1
chr12_47470653_47470804	0.46	PCED1B	PC-esterase domain containing 1B	2658	0.29
chr13_37006714_37007207	0.46	CCNA1	cyclin A1	465	0.85
chr5_158488269_158488591	0.46	EBF1	early B-cell factor 1	38271	0.17
chr12_22059820_22060034	0.46	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	3985	0.3
chr9_91146971_91147229	0.46	NXNL2	nucleoredoxin-like 2	2916	0.39
chr7_98970111_98970529	0.45	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	1552	0.28
chr22_36232810_36232961	0.45	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	3380	0.35
chr12_94580963_94581249	0.45	RP11-74K11.2		1286	0.5
chr13_76217437_76217800	0.45	LMO7	LIM domain 7	7159	0.18
chr8_107738861_107739281	0.45	OXR1	oxidation resistance 1	658	0.71
chr4_109532705_109532935	0.45	RPL34	ribosomal protein L34	8902	0.2
chr5_14153831_14154379	0.45	TRIO	trio Rho guanine nucleotide exchange factor	10276	0.32
chr7_134396917_134397381	0.45	CALD1	caldesmon 1	31854	0.2
chr5_16916952_16917142	0.45	MYO10	myosin X	411	0.87
chr6_56705417_56705587	0.45	DST	dystonin	2441	0.31
chr4_48700842_48701028	0.45	FRYL	FRY-like	17747	0.24
chr16_89990965_89991193	0.45	TUBB3	Tubulin beta-3 chain	1305	0.26
chr18_60117928_60118203	0.45	ZCCHC2	zinc finger, CCHC domain containing 2	72175	0.1
chr1_38910382_38910533	0.44	ENSG00000200796	.	48126	0.18
chr2_159651901_159652191	0.44	DAPL1	death associated protein-like 1	217	0.95
chr20_46412966_46413363	0.44	SULF2	sulfatase 2	1069	0.59
chr4_95855683_95855842	0.44	BMPR1B	bone morphogenetic protein receptor, type IB	61185	0.16
chr12_94385101_94385284	0.44	ENSG00000223126	.	17631	0.22
chr8_72273557_72273741	0.44	EYA1	eyes absent homolog 1 (Drosophila)	446	0.9
chr5_173000019_173000195	0.44	CTB-33O18.3		6539	0.26
chr2_46933523_46933944	0.44	SOCS5	suppressor of cytokine signaling 5	7407	0.22
chr11_122311553_122311819	0.44	ENSG00000252776	.	8232	0.23
chr1_109939510_109939955	0.44	SORT1	sortilin 1	841	0.56
chr9_112955081_112955242	0.44	C9orf152	chromosome 9 open reading frame 152	15308	0.23
chr6_116834038_116834189	0.43	TRAPPC3L	trafficking protein particle complex 3-like	607	0.55
chr9_103192985_103193136	0.43	MSANTD3	Myb/SANT-like DNA-binding domain containing 3	3341	0.21
chr1_169883940_169884437	0.43	SCYL3	SCY1-like 3 (S. cerevisiae)	20780	0.18
chr2_64877806_64878096	0.43	SERTAD2	SERTA domain containing 2	3096	0.31
chr2_188445720_188445877	0.43	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	15311	0.23
chr18_42313149_42313495	0.43	SETBP1	SET binding protein 1	36193	0.24
chr1_95330057_95330663	0.43	SLC44A3	solute carrier family 44, member 3	2527	0.28
chr11_31830603_31830754	0.43	PAX6	paired box 6	1175	0.49
chr12_118628413_118628612	0.43	TAOK3	TAO kinase 3	156	0.96

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX1_HOXA3_BARX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.8	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4	1.3	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.4	1.2	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.3	1.2	GO:0060013	righting reflex(GO:0060013)
0.3	0.9	GO:0030210	heparin biosynthetic process(GO:0030210)
0.3	0.9	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	0.6	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.6	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.2	0.9	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.2	0.5	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	0.5	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.2	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.2	0.5	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2	0.5	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.2	0.6	GO:0010107	potassium ion import(GO:0010107)
0.1	0.3	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.5	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	1.0	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.4	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.9	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.4	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.1	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.4	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.4	GO:0051451	myoblast migration(GO:0051451)
0.1	0.5	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.5	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.1	0.7	GO:0008354	germ cell migration(GO:0008354)
0.1	0.5	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.7	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.8	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.4	GO:0048539	bone marrow development(GO:0048539)
0.1	0.1	GO:0030202	heparin metabolic process(GO:0030202)
0.1	0.5	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.1	0.3	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.1	0.4	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.3	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1	0.8	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	1.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.4	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.4	GO:0010659	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.6	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	0.4	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.3	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.2	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.1	0.4	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1	0.3	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.4	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.9	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.1	0.1	GO:0061140	lung secretory cell differentiation(GO:0061140)
0.1	0.3	GO:0008218	bioluminescence(GO:0008218)
0.1	0.1	GO:0060242	contact inhibition(GO:0060242)
0.1	0.2	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.3	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.5	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.1	0.2	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.3	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.1	0.1	GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1	1.1	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.1	0.2	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.1	0.7	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.4	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.2	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1	0.3	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1	0.3	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.1	1.2	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	0.3	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	1.7	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.2	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.2	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.2	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.2	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.1	0.2	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.1	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.3	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.1	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	1.2	GO:0030199	collagen fibril organization(GO:0030199)
0.1	1.0	GO:0008038	neuron recognition(GO:0008038)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1	0.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.1	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.1	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.2	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.1	0.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.1	0.6	GO:0008347	glial cell migration(GO:0008347)
0.1	0.3	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.1	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.1	0.1	GO:0010159	specification of organ position(GO:0010159)
0.1	1.3	GO:0051101	regulation of DNA binding(GO:0051101)
0.1	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.1	0.3	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1	0.2	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.9	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.4	GO:0002076	osteoblast development(GO:0002076)
0.0	0.7	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.2	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.2	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.2	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	1.1	GO:0060606	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0	0.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.2	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:1903504	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.1	GO:0002686	negative regulation of leukocyte migration(GO:0002686)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.7	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.4	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0032616	interleukin-13 production(GO:0032616)
0.0	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	1.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.5	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.3	GO:0007141	male meiosis I(GO:0007141)
0.0	0.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.3	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	1.0	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.4	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.5	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.4	GO:0048536	spleen development(GO:0048536)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0043114	regulation of vascular permeability(GO:0043114)
0.0	0.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.4	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.1	GO:0060039	pericardium development(GO:0060039)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.0	GO:0042634	regulation of hair cycle(GO:0042634) regulation of hair follicle development(GO:0051797)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.2	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0045628	regulation of T-helper 2 cell differentiation(GO:0045628)
0.0	0.1	GO:0002118	aggressive behavior(GO:0002118)
0.0	0.3	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.0	0.7	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:1904063	negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.3	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.2	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0031935	regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0034444	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.6	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.2	GO:0001660	fever generation(GO:0001660)
0.0	0.2	GO:0046036	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.1	GO:0097035	phospholipid scrambling(GO:0017121) regulation of membrane lipid distribution(GO:0097035)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	3.1	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.2	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.3	GO:0048813	dendrite morphogenesis(GO:0048813)
0.0	0.1	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.5	GO:0046068	cGMP metabolic process(GO:0046068)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.5	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.2	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.2	GO:0034394	protein localization to cell surface(GO:0034394)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.3	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.3	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.1	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.4	GO:0006298	mismatch repair(GO:0006298)
0.0	0.0	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.2	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.0	GO:0045188	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.0	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0007320	insemination(GO:0007320)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0032106	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.2	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.3	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.0	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.3	GO:0030318	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0	0.1	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.2	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.0	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0007616	long-term memory(GO:0007616)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.2	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.5	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of dopamine secretion(GO:0033603)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.0	0.0	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.0	GO:1902170	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.5	GO:0007623	circadian rhythm(GO:0007623)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.0	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.2	GO:0051923	sulfation(GO:0051923)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.0	GO:0044319	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.2	GO:0042461	photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:1902913	positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.0	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.0	GO:0006545	glycine biosynthetic process(GO:0006545)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.6	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	0.6	GO:0043259	laminin-10 complex(GO:0043259)
0.2	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.2	0.5	GO:0005588	collagen type V trimer(GO:0005588)
0.1	1.2	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.4	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.8	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.6	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.1	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.4	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.3	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.8	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.4	GO:0010369	chromocenter(GO:0010369)
0.1	0.3	GO:0071437	invadopodium(GO:0071437)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.8	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.4	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.6	GO:0045178	basal part of cell(GO:0045178)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.6	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	2.3	GO:0030426	growth cone(GO:0030426)
0.0	1.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0044217	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.9	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.7	GO:0034704	calcium channel complex(GO:0034704)
0.0	6.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.2	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.0	GO:0031527	filopodium membrane(GO:0031527)
0.0	1.1	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.4	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.4	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.7	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	1.0	GO:0034705	potassium channel complex(GO:0034705)
0.0	0.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	2.4	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.0	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3	0.9	GO:0003680	AT DNA binding(GO:0003680)
0.2	0.7	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	0.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	1.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	1.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	0.7	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	0.5	GO:0042577	lipid phosphatase activity(GO:0042577)
0.2	1.4	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.6	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.7	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.4	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	0.6	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.4	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.4	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.4	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.6	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.4	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	0.4	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.3	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.3	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0070052	collagen V binding(GO:0070052)
0.1	0.3	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.9	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.5	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.9	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.3	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	1.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.9	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.8	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.3	GO:0050897	cobalt ion binding(GO:0050897)
0.1	0.5	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.3	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.4	GO:0017166	vinculin binding(GO:0017166)
0.1	0.9	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.6	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	1.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.2	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.1	GO:0045545	syndecan binding(GO:0045545)
0.1	0.5	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	1.3	GO:0005518	collagen binding(GO:0005518)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.2	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	1.0	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.8	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.2	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.4	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.4	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	1.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.3	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.2	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.2	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0051378	serotonin binding(GO:0051378)
0.0	0.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.2	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.4	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.0	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.4	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	1.0	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0005035	death receptor activity(GO:0005035)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.0	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.0	GO:0005497	androgen binding(GO:0005497)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.0	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.0	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	2.8	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	PID SHP2 PATHWAY	SHP2 signaling
0.1	1.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.5	PID CDC42 PATHWAY	CDC42 signaling events
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	0.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	0.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	2.2	NABA COLLAGENS	Genes encoding collagen proteins
0.0	2.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.6	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.3	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	3.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.8	PID BMP PATHWAY	BMP receptor signaling
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID FGF PATHWAY	FGF signaling pathway
0.0	0.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.4	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	3.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.9	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	0.2	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	1.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	1.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.9	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	1.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.5	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	1.0	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	0.8	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	2.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	1.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.5	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.6	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.0	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor

Results for DLX1_HOXA3_BARX2

Z-value: 1.02

Motif logo

Transcription factors associated with DLX1_HOXA3_BARX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the DLX1_HOXA3_BARX2 motif across conditions

Conditions sorted by the z-value of the DLX1_HOXA3_BARX2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX1_HOXA3_BARX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: