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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for DLX1_HOXA3_BARX2

Z-value: 1.02

Motif logo

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Transcription factors associated with DLX1_HOXA3_BARX2

Gene Symbol Gene ID Gene Info
ENSG00000144355.10 DLX1
ENSG00000105997.18 HOXA3
ENSG00000043039.5 BARX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
BARX2chr11_129245088_1292452706560.8163130.561.2e-01Click!
BARX2chr11_129243062_12924365624760.4123660.452.3e-01Click!
BARX2chr11_129242275_12924242634850.356232-0.412.7e-01Click!
BARX2chr11_129244074_12924455015230.5425840.324.0e-01Click!
BARX2chr11_129242593_12924275931590.3696550.324.0e-01Click!
DLX1chr2_172951434_17295158512450.4968920.771.5e-02Click!
DLX1chr2_172948607_1729487587860.6744540.771.6e-02Click!
DLX1chr2_172958009_17295816078200.2079620.703.5e-02Click!
DLX1chr2_172947668_17294781917250.3932100.636.9e-02Click!
DLX1chr2_172917249_172917400321440.1646370.521.5e-01Click!
HOXA3chr7_27150712_2715097226220.1043120.752.0e-02Click!
HOXA3chr7_27152154_2715230512350.1941790.646.4e-02Click!
HOXA3chr7_27150237_2715069130000.0964850.627.5e-02Click!
HOXA3chr7_27176258_2717640934920.0775440.617.9e-02Click!
HOXA3chr7_27151802_2715195315870.1538290.571.1e-01Click!

Activity of the DLX1_HOXA3_BARX2 motif across conditions

Conditions sorted by the z-value of the DLX1_HOXA3_BARX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_87036535_87037613 1.60 VGLL3
vestigial like 3 (Drosophila)
2778
0.42
chr7_129933276_129933885 1.58 CPA4
carboxypeptidase A4
461
0.76
chr7_93550787_93551002 1.27 GNG11
guanine nucleotide binding protein (G protein), gamma 11
117
0.96
chr21_17909068_17909746 1.11 ENSG00000207638
.
2002
0.33
chr7_95107815_95108198 1.06 ASB4
ankyrin repeat and SOCS box containing 4
7207
0.2
chr8_116675050_116675578 1.03 TRPS1
trichorhinophalangeal syndrome I
1409
0.6
chr3_105657205_105657471 1.02 CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
68942
0.15
chr13_24146066_24146217 0.98 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
1338
0.59
chr4_77506894_77507309 0.95 ENSG00000265314
.
10397
0.17
chr9_18474095_18474958 0.91 ADAMTSL1
ADAMTS-like 1
295
0.95
chr3_33318777_33319866 0.89 FBXL2
F-box and leucine-rich repeat protein 2
353
0.91
chr7_17720120_17720505 0.89 SNX13
sorting nexin 13
259779
0.02
chr11_131780111_131780399 0.87 NTM
neurotrimin
642
0.77
chr8_93114852_93115389 0.86 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
334
0.94
chr6_116833589_116833880 0.84 TRAPPC3L
trafficking protein particle complex 3-like
228
0.83
chr13_73081776_73081993 0.83 ENSG00000251715
.
47145
0.15
chr18_53089837_53090372 0.83 TCF4
transcription factor 4
361
0.89
chr6_126135984_126136135 0.79 NCOA7
nuclear receptor coactivator 7
305
0.89
chr20_50384318_50384901 0.79 ATP9A
ATPase, class II, type 9A
258
0.94
chr7_93552303_93552503 0.78 GNG11
guanine nucleotide binding protein (G protein), gamma 11
1392
0.38
chr12_66286178_66286489 0.76 RP11-366L20.2
Uncharacterized protein
10386
0.18
chr1_196577911_196578299 0.76 KCNT2
potassium channel, subfamily T, member 2
250
0.94
chr18_53090404_53090609 0.76 TCF4
transcription factor 4
763
0.7
chr4_57975072_57975270 0.75 IGFBP7-AS1
IGFBP7 antisense RNA 1
757
0.52
chr6_85823864_85824548 0.75 NT5E
5'-nucleotidase, ecto (CD73)
335603
0.01
chr17_19998529_19998923 0.74 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
279
0.92
chr11_12849556_12849989 0.73 RP11-47J17.3

4558
0.23
chr12_66220556_66220804 0.73 HMGA2
high mobility group AT-hook 2
1777
0.39
chr12_56917781_56918152 0.73 RBMS2
RNA binding motif, single stranded interacting protein 2
2183
0.23
chr12_78336292_78336638 0.72 NAV3
neuron navigator 3
23591
0.28
chr12_66221036_66221187 0.69 HMGA2
high mobility group AT-hook 2
2208
0.34
chr15_37179413_37179956 0.69 ENSG00000212511
.
34843
0.22
chr4_134070427_134071051 0.68 PCDH10
protocadherin 10
269
0.96
chr1_68697735_68698156 0.68 WLS
wntless Wnt ligand secretion mediator
18
0.98
chr3_112356169_112356393 0.68 CCDC80
coiled-coil domain containing 80
663
0.77
chr6_19691587_19692480 0.68 ENSG00000200957
.
49273
0.18
chr8_38855409_38855789 0.67 ADAM9
ADAM metallopeptidase domain 9
1094
0.34
chr1_84107245_84107582 0.67 ENSG00000223231
.
152147
0.04
chr10_60273912_60274168 0.66 BICC1
bicaudal C homolog 1 (Drosophila)
1140
0.65
chr13_38172411_38172686 0.66 POSTN
periostin, osteoblast specific factor
315
0.95
chr3_79066759_79066910 0.65 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
860
0.75
chr2_207998546_207999225 0.65 KLF7
Kruppel-like factor 7 (ubiquitous)
24
0.98
chr15_96878465_96878729 0.65 ENSG00000222651
.
2107
0.24
chr8_37350646_37351319 0.64 RP11-150O12.6

23557
0.24
chr1_87799796_87800719 0.64 LMO4
LIM domain only 4
2906
0.4
chr2_151340168_151340387 0.63 RND3
Rho family GTPase 3
1619
0.57
chr16_54968513_54968925 0.63 IRX5
iroquois homeobox 5
2735
0.43
chr20_45946936_45948261 0.63 AL031666.2
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
352
0.82
chr4_41215270_41215769 0.61 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
956
0.59
chr5_66311217_66311678 0.61 MAST4
microtubule associated serine/threonine kinase family member 4
10964
0.24
chr15_99794226_99794420 0.61 LRRC28
leucine rich repeat containing 28
2307
0.22
chr5_88080560_88081020 0.61 MEF2C
myocyte enhancer factor 2C
38815
0.18
chr10_6763782_6764322 0.61 PRKCQ
protein kinase C, theta
141789
0.05
chr20_10502111_10502382 0.61 SLX4IP
SLX4 interacting protein
86295
0.09
chr5_174178214_174178699 0.61 ENSG00000266890
.
281
0.94
chr11_111849006_111849202 0.61 DIXDC1
DIX domain containing 1
1071
0.39
chr10_86185479_86185663 0.60 CCSER2
coiled-coil serine-rich protein 2
876
0.74
chr4_157997366_157997978 0.60 GLRB
glycine receptor, beta
117
0.97
chr3_114477857_114478359 0.60 ZBTB20
zinc finger and BTB domain containing 20
10
0.99
chr11_106239153_106239583 0.60 RP11-680E19.1

104326
0.08
chr17_66700653_66700804 0.60 ENSG00000263690
.
61972
0.13
chr18_20612011_20612377 0.59 ENSG00000223023
.
7635
0.17
chr2_38295840_38295991 0.59 RMDN2-AS1
RMDN2 antisense RNA 1
1731
0.34
chr3_110791913_110792064 0.59 PVRL3
poliovirus receptor-related 3
973
0.53
chr5_149867786_149868254 0.59 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
2163
0.3
chr15_42749459_42749764 0.58 ZNF106
zinc finger protein 106
100
0.96
chr8_57086542_57086822 0.58 PLAG1
pleiomorphic adenoma gene 1
37156
0.12
chr2_58266503_58266768 0.57 VRK2
vaccinia related kinase 2
7094
0.27
chr4_157891142_157892336 0.57 PDGFC
platelet derived growth factor C
316
0.91
chr2_200446222_200446758 0.57 SATB2
SATB homeobox 2
110501
0.07
chr2_66668625_66669005 0.57 AC092669.1

153
0.89
chr4_82413627_82413778 0.56 RASGEF1B
RasGEF domain family, member 1B
20633
0.28
chr4_15471989_15472140 0.56 CC2D2A
coiled-coil and C2 domain containing 2A
427
0.85
chr10_101736542_101736753 0.56 DNMBP
dynamin binding protein
33029
0.15
chr20_43965593_43965922 0.56 SDC4
syndecan 4
11307
0.11
chr6_27060216_27060434 0.56 ENSG00000222800
.
17434
0.13
chr14_29859562_29859789 0.56 ENSG00000257522
.
11813
0.29
chr5_82767889_82768074 0.55 VCAN
versican
237
0.96
chr9_104248314_104249564 0.55 TMEM246
transmembrane protein 246
460
0.79
chr15_88020923_88021173 0.55 ENSG00000207150
.
3528
0.4
chr21_36253539_36254227 0.55 RUNX1
runt-related transcription factor 1
5597
0.33
chr4_108746841_108747185 0.55 SGMS2
sphingomyelin synthase 2
649
0.76
chr9_89952337_89952906 0.55 ENSG00000212421
.
77256
0.11
chr22_36233928_36234199 0.55 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
2202
0.43
chr15_80365541_80365692 0.55 ZFAND6
zinc finger, AN1-type domain 6
684
0.75
chr3_114169976_114170457 0.54 ZBTB20
zinc finger and BTB domain containing 20
3314
0.33
chr15_71054590_71054766 0.54 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
1091
0.55
chr1_39881370_39881756 0.54 MACF1
microtubule-actin crosslinking factor 1
1491
0.39
chr3_61546098_61546562 0.54 PTPRG
protein tyrosine phosphatase, receptor type, G
1255
0.64
chr6_163817634_163818149 0.54 QKI
QKI, KH domain containing, RNA binding
17784
0.29
chr1_162603392_162603656 0.54 DDR2
discoidin domain receptor tyrosine kinase 2
1264
0.48
chr5_58592476_58593460 0.54 PDE4D
phosphodiesterase 4D, cAMP-specific
21023
0.29
chr1_170640402_170640573 0.54 PRRX1
paired related homeobox 1
7409
0.3
chr8_131206424_131206650 0.54 ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
13429
0.23
chr1_68214173_68214559 0.54 ENSG00000238778
.
23970
0.19
chr12_89845524_89845923 0.54 POC1B
POC1 centriolar protein B
45311
0.13
chr6_86167890_86168219 0.53 NT5E
5'-nucleotidase, ecto (CD73)
8227
0.28
chr11_121966638_121966789 0.53 ENSG00000207971
.
3839
0.19
chr4_71479096_71479386 0.53 ENAM
enamelin
15220
0.15
chr10_69831641_69832005 0.53 HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
2071
0.33
chr15_99864758_99865035 0.53 AC022819.2
Uncharacterized protein
5068
0.23
chr17_35851874_35852313 0.53 DUSP14
dual specificity phosphatase 14
523
0.79
chr14_101867418_101867569 0.53 ENSG00000258498
.
159266
0.02
chr13_33858125_33858279 0.53 STARD13
StAR-related lipid transfer (START) domain containing 13
1690
0.4
chr4_6887879_6888223 0.52 TBC1D14
TBC1 domain family, member 14
22918
0.18
chr7_27202641_27202952 0.52 HOXA9
homeobox A9
2349
0.09
chr4_124339787_124340099 0.52 SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
18820
0.3
chr16_53244996_53245358 0.52 CHD9
chromodomain helicase DNA binding protein 9
2814
0.29
chr10_33620428_33620906 0.52 NRP1
neuropilin 1
2643
0.37
chr8_62625183_62625719 0.52 ASPH
aspartate beta-hydroxylase
1633
0.37
chr8_77599205_77599356 0.51 ZFHX4
zinc finger homeobox 4
3264
0.28
chr7_14028526_14029745 0.51 ETV1
ets variant 1
156
0.97
chr13_76588981_76589230 0.51 ENSG00000243274
.
119962
0.06
chr1_89447034_89447185 0.51 CCBL2
cysteine conjugate-beta lyase 2
11178
0.15
chr2_145210039_145210510 0.51 ZEB2
zinc finger E-box binding homeobox 2
22137
0.25
chr3_79411197_79411348 0.51 ENSG00000265193
.
145765
0.05
chr2_110656312_110656910 0.51 LIMS3
LIM and senescent cell antigen-like domains 3
343
0.93
chr10_115032925_115033406 0.51 ENSG00000238380
.
80019
0.11
chr3_120215962_120216316 0.51 FSTL1
follistatin-like 1
46039
0.16
chr6_26577102_26577344 0.51 ABT1
activator of basal transcription 1
19957
0.15
chr1_153585227_153585451 0.51 S100A16
S100 calcium binding protein A16
220
0.83
chr8_108506884_108507225 0.51 ANGPT1
angiopoietin 1
169
0.98
chr9_79483882_79484033 0.51 PRUNE2
prune homolog 2 (Drosophila)
37044
0.21
chrX_114829080_114829277 0.50 PLS3
plastin 3
1313
0.48
chr3_44063258_44064101 0.50 ENSG00000252980
.
48900
0.17
chr9_22008020_22008450 0.50 CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
717
0.61
chr3_174159101_174159924 0.50 NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
735
0.81
chr4_54063057_54063462 0.49 ENSG00000207385
.
68475
0.13
chr5_158524974_158525234 0.49 EBF1
early B-cell factor 1
1597
0.48
chr16_73089798_73090050 0.49 ZFHX3
zinc finger homeobox 3
3673
0.28
chr14_75039149_75039311 0.49 LTBP2
latent transforming growth factor beta binding protein 2
39545
0.13
chr5_107229567_107229740 0.49 ENSG00000251732
.
83323
0.11
chr1_151918063_151918251 0.48 THEM4
thioesterase superfamily member 4
35873
0.1
chr2_109271526_109272143 0.48 LIMS1
LIM and senescent cell antigen-like domains 1
325
0.91
chr2_128492018_128492224 0.48 SFT2D3
SFT2 domain containing 3
33524
0.13
chr2_198540490_198540682 0.48 RFTN2
raftlin family member 2
133
0.96
chr17_42214986_42215221 0.48 ENSG00000212446
.
1746
0.18
chr3_116583114_116583333 0.48 ENSG00000265433
.
14009
0.25
chrX_16825753_16826181 0.48 TXLNG
taxilin gamma
21412
0.16
chr20_56749874_56750278 0.48 C20orf85
chromosome 20 open reading frame 85
24116
0.19
chr18_56244152_56244311 0.48 RP11-126O1.2

19929
0.14
chr7_151297260_151297484 0.48 PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
32067
0.18
chr6_28442401_28443147 0.48 ZSCAN23
zinc finger and SCAN domain containing 23
31530
0.13
chr8_77589944_77590318 0.48 ZFHX4
zinc finger homeobox 4
3323
0.29
chr8_48648492_48649280 0.48 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
2762
0.26
chr7_151328064_151328292 0.47 PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
1261
0.55
chr6_148829582_148830289 0.47 ENSG00000223322
.
15441
0.29
chr5_111090218_111090459 0.47 NREP
neuronal regeneration related protein
1610
0.42
chr6_165341513_165341675 0.47 C6orf118
chromosome 6 open reading frame 118
380748
0.01
chr7_28726429_28726958 0.47 CREB5
cAMP responsive element binding protein 5
1095
0.68
chr14_53509566_53509717 0.47 RP11-368P15.3

6168
0.27
chr6_27859319_27859470 0.47 HIST1H3J
histone cluster 1, H3j
824
0.31
chr12_120246427_120246712 0.47 CIT
citron (rho-interacting, serine/threonine kinase 21)
5382
0.27
chr6_5471426_5471612 0.47 RP1-232P20.1

13211
0.27
chr3_59101471_59101696 0.47 C3orf67
chromosome 3 open reading frame 67
65773
0.15
chr10_73725086_73725706 0.47 CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
1273
0.55
chr6_1613704_1614304 0.46 FOXC1
forkhead box C1
3323
0.37
chr1_79506717_79506893 0.46 ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
34402
0.23
chr15_80840560_80840711 0.46 RP11-379K22.2

14650
0.18
chr11_114167823_114168031 0.46 NNMT
nicotinamide N-methyltransferase
158
0.96
chr5_3597777_3597928 0.46 IRX1
iroquois homeobox 1
1684
0.41
chr19_1361544_1361801 0.46 MUM1
melanoma associated antigen (mutated) 1
5309
0.1
chr12_47470653_47470804 0.46 PCED1B
PC-esterase domain containing 1B
2658
0.29
chr13_37006714_37007207 0.46 CCNA1
cyclin A1
465
0.85
chr5_158488269_158488591 0.46 EBF1
early B-cell factor 1
38271
0.17
chr12_22059820_22060034 0.46 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
3985
0.3
chr9_91146971_91147229 0.46 NXNL2
nucleoredoxin-like 2
2916
0.39
chr7_98970111_98970529 0.45 ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
1552
0.28
chr22_36232810_36232961 0.45 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
3380
0.35
chr12_94580963_94581249 0.45 RP11-74K11.2

1286
0.5
chr13_76217437_76217800 0.45 LMO7
LIM domain 7
7159
0.18
chr8_107738861_107739281 0.45 OXR1
oxidation resistance 1
658
0.71
chr4_109532705_109532935 0.45 RPL34
ribosomal protein L34
8902
0.2
chr5_14153831_14154379 0.45 TRIO
trio Rho guanine nucleotide exchange factor
10276
0.32
chr7_134396917_134397381 0.45 CALD1
caldesmon 1
31854
0.2
chr5_16916952_16917142 0.45 MYO10
myosin X
411
0.87
chr6_56705417_56705587 0.45 DST
dystonin
2441
0.31
chr4_48700842_48701028 0.45 FRYL
FRY-like
17747
0.24
chr16_89990965_89991193 0.45 TUBB3
Tubulin beta-3 chain
1305
0.26
chr18_60117928_60118203 0.45 ZCCHC2
zinc finger, CCHC domain containing 2
72175
0.1
chr1_38910382_38910533 0.44 ENSG00000200796
.
48126
0.18
chr2_159651901_159652191 0.44 DAPL1
death associated protein-like 1
217
0.95
chr20_46412966_46413363 0.44 SULF2
sulfatase 2
1069
0.59
chr4_95855683_95855842 0.44 BMPR1B
bone morphogenetic protein receptor, type IB
61185
0.16
chr12_94385101_94385284 0.44 ENSG00000223126
.
17631
0.22
chr8_72273557_72273741 0.44 EYA1
eyes absent homolog 1 (Drosophila)
446
0.9
chr5_173000019_173000195 0.44 CTB-33O18.3

6539
0.26
chr2_46933523_46933944 0.44 SOCS5
suppressor of cytokine signaling 5
7407
0.22
chr11_122311553_122311819 0.44 ENSG00000252776
.
8232
0.23
chr1_109939510_109939955 0.44 SORT1
sortilin 1
841
0.56
chr9_112955081_112955242 0.44 C9orf152
chromosome 9 open reading frame 152
15308
0.23
chr6_116834038_116834189 0.43 TRAPPC3L
trafficking protein particle complex 3-like
607
0.55
chr9_103192985_103193136 0.43 MSANTD3
Myb/SANT-like DNA-binding domain containing 3
3341
0.21
chr1_169883940_169884437 0.43 SCYL3
SCY1-like 3 (S. cerevisiae)
20780
0.18
chr2_64877806_64878096 0.43 SERTAD2
SERTA domain containing 2
3096
0.31
chr2_188445720_188445877 0.43 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
15311
0.23
chr18_42313149_42313495 0.43 SETBP1
SET binding protein 1
36193
0.24
chr1_95330057_95330663 0.43 SLC44A3
solute carrier family 44, member 3
2527
0.28
chr11_31830603_31830754 0.43 PAX6
paired box 6
1175
0.49
chr12_118628413_118628612 0.43 TAOK3
TAO kinase 3
156
0.96

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of DLX1_HOXA3_BARX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4 1.3 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.4 1.2 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.3 1.2 GO:0060013 righting reflex(GO:0060013)
0.3 0.9 GO:0030210 heparin biosynthetic process(GO:0030210)
0.3 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.6 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.2 0.6 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.2 0.9 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.2 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 0.5 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.2 0.5 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2 0.5 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.2 0.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0072033 renal vesicle formation(GO:0072033)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 1.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.4 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.4 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.4 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.4 GO:0051451 myoblast migration(GO:0051451)
0.1 0.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.5 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.1 0.7 GO:0008354 germ cell migration(GO:0008354)
0.1 0.5 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.4 GO:0048539 bone marrow development(GO:0048539)
0.1 0.1 GO:0030202 heparin metabolic process(GO:0030202)
0.1 0.5 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.2 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.1 0.3 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.3 GO:0060346 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1 0.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.4 GO:0010659 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.6 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.4 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.1 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.9 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.1 GO:0061140 lung secretory cell differentiation(GO:0061140)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.1 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.5 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 0.2 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.1 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1 1.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.2 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.1 0.7 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.2 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1 0.3 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1 0.3 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 1.2 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.3 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 1.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.1 0.2 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.1 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.1 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 1.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.0 GO:0008038 neuron recognition(GO:0008038)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.2 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.2 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.1 0.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.6 GO:0008347 glial cell migration(GO:0008347)
0.1 0.3 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.1 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.1 0.1 GO:0010159 specification of organ position(GO:0010159)
0.1 1.3 GO:0051101 regulation of DNA binding(GO:0051101)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.3 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.9 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.7 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.2 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 1.1 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:1903504 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.7 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.4 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0032616 interleukin-13 production(GO:0032616)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 1.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.3 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.0 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.4 GO:0048536 spleen development(GO:0048536)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0042634 regulation of hair cycle(GO:0042634) regulation of hair follicle development(GO:0051797)
0.0 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.0 GO:0045628 regulation of T-helper 2 cell differentiation(GO:0045628)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.3 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.7 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:1904063 negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.3 GO:0047496 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0031935 regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0034444 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0001660 fever generation(GO:0001660)
0.0 0.2 GO:0046036 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0097035 phospholipid scrambling(GO:0017121) regulation of membrane lipid distribution(GO:0097035)
0.0 0.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.5 GO:0046068 cGMP metabolic process(GO:0046068)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.5 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.3 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.3 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.0 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.0 GO:0045188 circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.0 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0032106 positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.2 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.3 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.3 GO:0030318 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0 0.1 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.0 GO:0051955 regulation of amino acid transport(GO:0051955)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.0 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0007616 long-term memory(GO:0007616)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.5 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of dopamine secretion(GO:0033603)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0043084 penile erection(GO:0043084)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.0 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.0 0.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.5 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.0 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.1 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.2 GO:0051923 sulfation(GO:0051923)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.0 GO:0044319 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0042461 photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:1902913 positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.0 GO:0035510 DNA dealkylation(GO:0035510)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0006545 glycine biosynthetic process(GO:0006545)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.6 GO:0043259 laminin-10 complex(GO:0043259)
0.2 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.4 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.8 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0071437 invadopodium(GO:0071437)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.3 GO:0030426 growth cone(GO:0030426)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0044217 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.7 GO:0034704 calcium channel complex(GO:0034704)
0.0 6.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.0 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.0 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 2.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.0 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.7 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 1.4 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.1 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.6 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.4 GO:0004470 malic enzyme activity(GO:0004470)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.3 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0017166 vinculin binding(GO:0017166)
0.1 0.9 GO:0043498 obsolete cell surface binding(GO:0043498)
0.1 0.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.1 GO:0045545 syndecan binding(GO:0045545)
0.1 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 1.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0005497 androgen binding(GO:0005497)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.0 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 2.8 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 PID SHP2 PATHWAY SHP2 signaling
0.1 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.9 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.8 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.0 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.0 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.0 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor