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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for DMC1

Z-value: 0.83

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Transcription factors associated with DMC1

Gene Symbol	Gene ID	Gene Info
DMC1 Ensembl NCBI GeneCards UniProt	ENSG00000100206.5	DMC1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
DMC1	chr22_38966531_38967313	631	0.677684	-0.59	9.3e-02	Click!
DMC1	chr22_38965920_38966142	105	0.960556	-0.50	1.7e-01	Click!
DMC1	chr22_38965750_38965911	306	0.877472	-0.46	2.1e-01	Click!

Activity of the DMC1 motif across conditions

Conditions sorted by the z-value of the DMC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_36302041_36302306	0.36	RANBP3L	RAN binding protein 3-like	43	0.98
chr4_183481639_183481857	0.35	ENSG00000252343	.	11936	0.26
chr7_130591247_130591471	0.33	ENSG00000226380	.	29061	0.21
chr1_63190926_63191187	0.32	RP11-230B22.1		36903	0.16
chr15_80364416_80364822	0.31	ZFAND6	zinc finger, AN1-type domain 6	287	0.93
chr15_42082923_42083265	0.30	AC073657.1	Uncharacterized protein	6865	0.12
chr12_889349_889584	0.29	ENSG00000221439	.	833	0.66
chr2_102374666_102374817	0.29	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	38985	0.21
chr17_74142136_74142287	0.29	RNF157-AS1	RNF157 antisense RNA 1	4614	0.13
chr4_109347461_109347695	0.28	ENSG00000266046	.	150718	0.04
chr21_38352575_38353327	0.28	HLCS	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)	23	0.97
chr5_38650925_38651503	0.28	LIFR	leukemia inhibitory factor receptor alpha	55708	0.13
chr5_38844869_38845152	0.27	OSMR	oncostatin M receptor	950	0.68
chr6_53480929_53481080	0.27	GCLC	glutamate-cysteine ligase, catalytic subunit	764	0.66
chr2_227598429_227598675	0.27	IRS1	insulin receptor substrate 1	65923	0.11
chr1_215739347_215739498	0.27	KCTD3	potassium channel tetramerization domain containing 3	1313	0.59
chr12_109248389_109248808	0.27	SSH1	slingshot protein phosphatase 1	2761	0.21
chr7_97987211_97987389	0.26	RP11-307C18.1		35135	0.15
chr8_59962698_59962849	0.26	RP11-328K2.1		57276	0.12
chr4_90674169_90674343	0.26	RP11-115D19.1		71593	0.11
chr3_152314332_152314547	0.25	RP11-362A9.3		99837	0.08
chr18_7618536_7618784	0.25	PTPRM	protein tyrosine phosphatase, receptor type, M	50843	0.16
chr19_50031610_50031873	0.24	RCN3	reticulocalbin 3, EF-hand calcium binding domain	142	0.87
chr4_187765290_187765672	0.24	ENSG00000252382	.	13129	0.29
chr1_83285095_83285395	0.24	LPHN2	latrophilin 2	839672	0.0
chr20_32158375_32158526	0.24	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	8264	0.19
chr7_22538999_22539909	0.24	STEAP1B	STEAP family member 1B	342	0.91
chr3_135885490_135885641	0.24	MSL2	male-specific lethal 2 homolog (Drosophila)	27831	0.21
chr1_243990574_243990792	0.23	AKT3	v-akt murine thymoma viral oncogene homolog 3	15855	0.22
chr14_99614015_99614166	0.23	AL162151.4		10663	0.28
chr7_116151462_116151613	0.23	CAV2	caveolin 2	11703	0.15
chr5_96000350_96000501	0.23	CAST	calpastatin	1668	0.37
chr2_233497598_233498235	0.23	EFHD1	EF-hand domain family, member D1	22	0.97
chr6_5498765_5499077	0.22	RP1-232P20.1		40613	0.2
chr2_16817553_16817704	0.22	FAM49A	family with sequence similarity 49, member A	13284	0.3
chr5_9534352_9534503	0.22	CTD-2201E9.2		11137	0.18
chr12_116892640_116892791	0.22	ENSG00000264037	.	26592	0.24
chr3_190063110_190063261	0.21	CLDN1	claudin 1	22921	0.21
chr10_63642613_63642764	0.21	ARID5B	AT rich interactive domain 5B (MRF1-like)	18371	0.24
chr10_97049571_97049740	0.21	PDLIM1	PDZ and LIM domain 1	1126	0.58
chr22_44608120_44608309	0.21	PARVG	parvin, gamma	30473	0.22
chr14_70140824_70141065	0.21	SRSF5	serine/arginine-rich splicing factor 5	52673	0.13
chr13_26623410_26623899	0.21	SHISA2	shisa family member 2	1515	0.52
chr13_71953353_71953512	0.21	DACH1	dachshund homolog 1 (Drosophila)	487475	0.01
chr9_133721695_133722074	0.21	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	11431	0.21
chr20_46110875_46111026	0.21	ENSG00000202186	.	2175	0.28
chr13_99880901_99881195	0.20	ENSG00000201793	.	23086	0.16
chr5_107767649_107767800	0.20	FBXL17	F-box and leucine-rich repeat protein 17	49925	0.19
chr5_112823124_112823740	0.20	MCC	mutated in colorectal cancers	1095	0.49
chr5_119951633_119951784	0.20	PRR16	proline rich 16	1075	0.68
chrX_114468679_114469096	0.20	LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	252	0.93
chr18_70080364_70080515	0.20	CBLN2	cerebellin 2 precursor	130350	0.06
chr18_28741984_28742214	0.20	DSC1	desmocollin 1	720	0.67
chr9_33510457_33510690	0.19	RP11-255A11.2		4198	0.19
chr11_120202601_120202952	0.19	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	5011	0.19
chr7_1443631_1443991	0.19	MICALL2	MICAL-like 2	55151	0.11
chr7_107808332_107808483	0.19	NRCAM	neuronal cell adhesion molecule	7395	0.25
chr22_37957123_37957770	0.19	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	959	0.43
chr7_15597655_15597806	0.19	AGMO	alkylglycerol monooxygenase	3910	0.36
chr1_117342787_117343202	0.18	CD2	CD2 molecule	45905	0.14
chr15_48919611_48919986	0.18	FBN1	fibrillin 1	18120	0.26
chr4_178167836_178167987	0.18	RP11-487E13.1	Uncharacterized protein	2016	0.4
chr12_57522507_57523183	0.18	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	38	0.64
chr4_154125931_154126175	0.18	TRIM2	tripartite motif containing 2	435	0.87
chr11_125036127_125036278	0.18	PKNOX2	PBX/knotted 1 homeobox 2	1552	0.29
chr14_55741621_55741910	0.18	FBXO34	F-box protein 34	2893	0.32
chr8_62504364_62504526	0.18	ENSG00000222898	.	40126	0.18
chr8_24799685_24800298	0.18	CTD-2168K21.2		14144	0.18
chr3_74472777_74472928	0.18	CNTN3	contactin 3 (plasmacytoma associated)	97439	0.09
chr12_28125138_28125289	0.18	PTHLH	parathyroid hormone-like hormone	297	0.92
chr14_55035520_55036036	0.18	SAMD4A	sterile alpha motif domain containing 4A	1141	0.56
chr2_8422146_8422297	0.18	AC011747.7		393675	0.01
chr8_69242814_69243988	0.18	C8orf34	chromosome 8 open reading frame 34	56	0.82
chr10_44139678_44139829	0.18	ZNF32-AS1	ZNF32 antisense RNA 1	433	0.76
chr4_77704559_77704807	0.18	RP11-359D14.3		18434	0.19
chr2_88499667_88499997	0.17	THNSL2	threonine synthase-like 2 (S. cerevisiae)	28853	0.14
chr17_42293603_42293754	0.17	UBTF	upstream binding transcription factor, RNA polymerase I	2192	0.13
chr1_42384263_42384523	0.17	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	15	0.99
chr21_22573602_22573755	0.17	AP001136.2		25472	0.24
chr9_8857014_8857547	0.17	PTPRD	protein tyrosine phosphatase, receptor type, D	496	0.84
chr8_107738582_107738843	0.17	OXR1	oxidation resistance 1	299	0.9
chr3_170148637_170148924	0.17	CLDN11	claudin 11	11925	0.25
chr15_64635802_64635953	0.17	ENSG00000252774	.	1139	0.39
chr17_48714816_48714967	0.17	ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	2673	0.17
chr11_18341339_18341613	0.17	HPS5	Hermansky-Pudlak syndrome 5	2245	0.19
chr3_15351793_15351990	0.17	ENSG00000238891	.	6236	0.16
chr17_1250998_1251685	0.17	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	13247	0.18
chr9_130717953_130718104	0.17	FAM102A	family with sequence similarity 102, member A	5027	0.11
chr8_41164878_41165029	0.17	SFRP1	secreted frizzled-related protein 1	444	0.81
chr7_130680237_130680465	0.16	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	11483	0.25
chr20_34743149_34743400	0.16	RP11-234K24.3		381	0.62
chr6_155057921_155058172	0.16	SCAF8	SR-related CTD-associated factor 8	3496	0.32
chr1_55701600_55701751	0.16	ENSG00000265822	.	10361	0.22
chr2_189434243_189434394	0.16	GULP1	GULP, engulfment adaptor PTB domain containing 1	447	0.91
chr14_68454519_68454814	0.16	CTD-2566J3.1		142247	0.04
chr6_18043342_18043513	0.16	KIF13A	kinesin family member 13A	55573	0.13
chr4_169616116_169616373	0.16	ENSG00000206613	.	8377	0.21
chr8_79965001_79965152	0.16	ENSG00000264969	.	44522	0.21
chr6_25193336_25193538	0.16	ENSG00000222373	.	796	0.63
chr15_94473358_94473509	0.16	ENSG00000222409	.	33177	0.25
chr5_40915264_40915466	0.15	ENSG00000253098	.	4135	0.21
chr3_30722457_30722608	0.15	RP11-1024P17.1		16621	0.27
chr20_38091019_38091170	0.15	ENSG00000241840	.	109692	0.07
chr2_145594298_145594531	0.15	ZEB2	zinc finger E-box binding homeobox 2	315793	0.01
chr4_138480079_138480230	0.15	PCDH18	protocadherin 18	26506	0.28
chr3_43682701_43682852	0.15	ANO10	anoctamin 10	19216	0.24
chr4_138454899_138455069	0.15	PCDH18	protocadherin 18	1336	0.63
chr1_226919798_226919959	0.15	ITPKB	inositol-trisphosphate 3-kinase B	5281	0.26
chr2_85515912_85516063	0.15	ENSG00000221579	.	10170	0.13
chr22_26925865_26926016	0.15	TPST2	tyrosylprotein sulfotransferase 2	10897	0.13
chr4_54564237_54564388	0.15	RP11-317M11.1		2244	0.33
chr12_111905255_111905406	0.15	ATXN2	ataxin 2	3034	0.24
chr18_496799_496950	0.15	COLEC12	collectin sub-family member 12	3848	0.24
chr2_44397964_44398115	0.15	PPM1B	protein phosphatase, Mg2+/Mn2+ dependent, 1B	1990	0.26
chr6_80656707_80657785	0.15	ELOVL4	ELOVL fatty acid elongase 4	51	0.98
chr7_114649841_114649992	0.15	MDFIC	MyoD family inhibitor domain containing	75992	0.12
chr18_2846122_2846273	0.15	EMILIN2	elastin microfibril interfacer 2	831	0.57
chr17_762924_763100	0.15	NXN	nucleoredoxin	4325	0.18
chr4_114677811_114678169	0.15	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	4234	0.36
chr21_32591500_32591929	0.15	TIAM1	T-cell lymphoma invasion and metastasis 1	57369	0.16
chr7_17341776_17341927	0.15	AC003075.4		2870	0.29
chr19_49521308_49522757	0.15	LHB	luteinizing hormone beta polypeptide	1694	0.14
chr8_95448497_95449318	0.15	FSBP	fibrinogen silencer binding protein	263	0.93
chr2_87811764_87811915	0.15	RP11-1399P15.1		34286	0.22
chrX_24497462_24497656	0.15	PDK3	pyruvate dehydrogenase kinase, isozyme 3	13986	0.21
chr13_60348574_60349034	0.14	DIAPH3-AS1	DIAPH3 antisense RNA 1	238081	0.02
chr1_6521246_6521397	0.14	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	4369	0.12
chr6_46459858_46460009	0.14	RP11-795J1.1		144	0.62
chr3_66502947_66503098	0.14	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1	48334	0.18
chr7_130663390_130663541	0.14	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	5403	0.28
chrX_12029343_12029494	0.14	ENSG00000206792	.	43627	0.19
chr2_201375425_201375576	0.14	KCTD18	potassium channel tetramerization domain containing 18	709	0.45
chr6_72103286_72103437	0.14	ENSG00000207827	.	9963	0.21
chr16_23144177_23144367	0.14	USP31	ubiquitin specific peptidase 31	16319	0.22
chr5_52206164_52206315	0.14	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	78917	0.09
chr13_63982821_63982972	0.14	LINC00395	long intergenic non-protein coding RNA 395	308255	0.01
chr3_175244326_175245006	0.14	ENSG00000201648	.	82601	0.1
chr4_148602160_148602311	0.14	PRMT10	protein arginine methyltransferase 10 (putative)	3041	0.27
chrX_20157621_20157927	0.14	EIF1AX-AS1	EIF1AX antisense RNA 1	312	0.82
chr7_104660604_104660779	0.14	KMT2E	lysine (K)-specific methyltransferase 2E	5783	0.17
chr15_92499471_92499678	0.14	SLCO3A1	solute carrier organic anion transporter family, member 3A1	102223	0.08
chr11_43665243_43665394	0.14	HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12	36941	0.17
chr9_82427303_82427454	0.14	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	105697	0.08
chr5_172306134_172306575	0.13	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	25866	0.16
chr14_61224053_61224421	0.13	MNAT1	MNAT CDK-activating kinase assembly factor 1	22743	0.2
chr17_61353070_61353290	0.13	RP11-269G24.2		37702	0.15
chr5_77843393_77843700	0.13	LHFPL2	lipoma HMGIC fusion partner-like 2	1428	0.58
chr11_118504420_118504703	0.13	AP002954.3		2777	0.17
chr7_111201271_111201551	0.13	IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	569	0.87
chr9_3794388_3794539	0.13	RP11-252M18.3		81121	0.11
chr2_144006322_144006473	0.13	RP11-190J23.1		76656	0.11
chr11_14995465_14995616	0.13	CALCA	calcitonin-related polypeptide alpha	1640	0.48
chr4_143481342_143481493	0.13	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	405	0.92
chr8_131257957_131258144	0.13	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	1238	0.6
chr8_131577804_131578063	0.13	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	122027	0.06
chr9_95610203_95610354	0.13	ZNF484	zinc finger protein 484	8322	0.17
chr1_23523630_23523879	0.13	HTR1D	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled	2532	0.23
chr1_8686332_8686483	0.13	RERE	arginine-glutamic acid dipeptide (RE) repeats	1968	0.44
chr5_15533409_15533775	0.13	FBXL7	F-box and leucine-rich repeat protein 7	32045	0.23
chr4_20289069_20289220	0.13	SLIT2	slit homolog 2 (Drosophila)	32601	0.24
chr3_116164058_116164214	0.13	LSAMP	limbic system-associated membrane protein	242	0.96
chr2_181995547_181995698	0.13	UBE2E3	ubiquitin-conjugating enzyme E2E 3	148872	0.04
chr6_132721617_132721768	0.13	MOXD1	monooxygenase, DBH-like 1	922	0.69
chr8_99952075_99952653	0.13	STK3	serine/threonine kinase 3	2435	0.25
chr3_168744118_168744269	0.13	MECOM	MDS1 and EVI1 complex locus	101629	0.08
chr10_35079377_35079528	0.13	PARD3	par-3 family cell polarity regulator	24797	0.2
chr4_57156140_57156443	0.13	ENSG00000252489	.	1541	0.39
chr5_35855125_35855276	0.12	IL7R	interleukin 7 receptor	1197	0.5
chr6_160509984_160510135	0.12	IGF2R	insulin-like growth factor 2 receptor	3966	0.27
chr19_4473895_4474732	0.12	HDGFRP2	Hepatoma-derived growth factor-related protein 2	576	0.53
chr1_61598053_61598265	0.12	RP4-802A10.1		7754	0.25
chr7_80543186_80543337	0.12	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	5238	0.35
chr3_12925603_12925754	0.12	AC034198.7		33520	0.13
chr5_16827159_16827310	0.12	ENSG00000253093	.	26869	0.22
chr12_70937490_70937641	0.12	RP11-588H23.3		23579	0.22
chr1_103573283_103573505	0.12	COL11A1	collagen, type XI, alpha 1	340	0.94
chr4_41122983_41123211	0.12	ENSG00000207198	.	7138	0.23
chr14_91525121_91525272	0.12	RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	1282	0.35
chr2_115419198_115419381	0.12	DPP10-AS3	DPP10 antisense RNA 3	171836	0.03
chr4_90056009_90056160	0.12	ENSG00000212226	.	4081	0.27
chr22_36232996_36233711	0.12	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	2912	0.37
chr2_145261378_145261529	0.12	ZEB2	zinc finger E-box binding homeobox 2	13662	0.24
chr5_112481657_112481808	0.12	MCC	mutated in colorectal cancers	88642	0.09
chr6_108108889_108109040	0.12	SCML4	sex comb on midleg-like 4 (Drosophila)	15509	0.27
chr1_193509624_193509775	0.12	ENSG00000252241	.	191375	0.03
chr21_36359858_36360101	0.12	RUNX1	runt-related transcription factor 1	61483	0.16
chr2_112195991_112196142	0.12	ENSG00000266139	.	117398	0.07
chr7_137638804_137638955	0.12	AC022173.2		785	0.68
chr13_41487964_41488115	0.12	SUGT1P3	SUGT1 pseudogene 3	7808	0.19
chr20_22756193_22756438	0.12	ENSG00000265151	.	42376	0.2
chr9_123693983_123694176	0.12	TRAF1	TNF receptor-associated factor 1	2628	0.31
chr3_8493679_8493830	0.12	LMCD1-AS1	LMCD1 antisense RNA 1 (head to head)	49530	0.14
chr7_25431142_25431293	0.12	ENSG00000202233	.	126942	0.05
chr6_73456305_73456456	0.12	KCNQ5-IT1	KCNQ5 intronic transcript 1 (non-protein coding)	116157	0.06
chr6_27440042_27440937	0.12	ZNF184	zinc finger protein 184	29	0.98
chr12_78836151_78836302	0.12	NAV3	neuron navigator 3	243370	0.02
chr11_86085513_86085741	0.12	CCDC81	coiled-coil domain containing 81	151	0.96
chr3_87487041_87487197	0.12	POU1F1	POU class 1 homeobox 1	161382	0.04
chr13_52217695_52217893	0.12	ENSG00000242893	.	49443	0.11
chr18_66506011_66506162	0.12	CCDC102B	coiled-coil domain containing 102B	2085	0.36

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of DMC1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0071504	cellular response to heparin(GO:0071504)
0.1	0.2	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.1	GO:1900115	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0097531	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.0	GO:0060510	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0	0.2	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.0	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.0	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.0	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.0	GO:0072191	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.0	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.2	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.0	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.3	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.1	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.0	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID SHP2 PATHWAY	SHP2 signaling
0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo