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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for DUXA

Z-value: 2.01

Motif logo

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Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
DUXA
ENSG00000258873.2 double homeobox A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_57684363_57684522DUXA56310.1349850.392.9e-01Click!
chr19_57683645_57683950DUXA49860.139304-0.117.7e-01Click!
chr19_57682857_57683287DUXA42610.1463620.107.9e-01Click!

Activity of the DUXA motif across conditions

Conditions sorted by the z-value of the DUXA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_157749235_157750071 0.92 ENSG00000263848
 .
 122116
 0.06
chr14_86001323_86001474 0.81 FLRT2
 fibronectin leucine rich transmembrane protein 2
 4826
 0.27
chr5_53753293_53753597 0.80 HSPB3
 heat shock 27kDa protein 3
 2000
 0.44
chr16_54968513_54968925 0.80 IRX5
 iroquois homeobox 5
 2735
 0.43
chr6_12573314_12573545 0.74 PHACTR1
 phosphatase and actin regulator 1
 144464
 0.05
chr17_29888799_29888950 0.73 ENSG00000207614
 .
 1859
 0.19
chr5_24644888_24645378 0.70 CDH10
 cadherin 10, type 2 (T2-cadherin)
 46
 0.99
chr11_131780111_131780399 0.67 NTM
 neurotrimin
 642
 0.77
chr2_38265076_38265999 0.66 RMDN2-AS1
 RMDN2 antisense RNA 1
 2053
 0.33
chr15_37179413_37179956 0.66 ENSG00000212511
 .
 34843
 0.22
chr4_81192022_81192173 0.65 FGF5
 fibroblast growth factor 5
 4304
 0.29
chr1_165665531_165665807 0.64 ALDH9A1
 aldehyde dehydrogenase 9 family, member A1
 1876
 0.34
chr20_43970794_43971114 0.63 SDC4
 syndecan 4
 6110
 0.13
chr4_86700524_86700675 0.62 ARHGAP24
 Rho GTPase activating protein 24
 740
 0.76
chr8_49831086_49831370 0.62 SNAI2
 snail family zinc finger 2
 2760
 0.41
chr5_111090218_111090459 0.62 NREP
 neuronal regeneration related protein
 1610
 0.42
chr8_70406794_70407007 0.62 SULF1
 sulfatase 1
 1872
 0.5
chr3_66139685_66140118 0.61 SLC25A26
 solute carrier family 25 (S-adenosylmethionine carrier), member 26
 20616
 0.25
chr6_152701576_152701930 0.60 SYNE1-AS1
 SYNE1 antisense RNA 1
 72
 0.97
chr17_67137246_67137397 0.58 ABCA6
 ATP-binding cassette, sub-family A (ABC1), member 6
 694
 0.69
chr6_169653692_169653887 0.58 THBS2
 thrombospondin 2
 350
 0.92
chr3_175389807_175390608 0.57 ENSG00000201648
 .
 62940
 0.12
chr5_102202832_102203172 0.57 PAM
 peptidylglycine alpha-amidating monooxygenase
 1182
 0.66
chr22_46462951_46463814 0.57 RP6-109B7.4
2389
 0.16
chr3_149371362_149371801 0.56 WWTR1-AS1
 WWTR1 antisense RNA 1
 3226
 0.2
chr9_21688149_21688723 0.55 ENSG00000244230
 .
 10877
 0.24
chr3_114343007_114343163 0.55 ZBTB20
 zinc finger and BTB domain containing 20
 32
 0.99
chr12_78336292_78336638 0.54 NAV3
 neuron navigator 3
 23591
 0.28
chr20_56706361_56706780 0.54 C20orf85
 chromosome 20 open reading frame 85
 19390
 0.21
chr1_68297324_68297475 0.54 GNG12-AS1
 GNG12 antisense RNA 1
 587
 0.71
chr13_110957949_110958238 0.53 COL4A2
 collagen, type IV, alpha 2
 66
 0.97
chr11_122072907_122073271 0.53 ENSG00000207994
 .
 50073
 0.12
chr21_32715523_32716836 0.53 TIAM1
 T-cell lymphoma invasion and metastasis 1
 415
 0.91
chr2_65889672_65889956 0.53 ENSG00000265899
 .
 4576
 0.32
chr4_54213222_54213526 0.53 SCFD2
 sec1 family domain containing 2
 18854
 0.21
chr7_93552303_93552503 0.52 GNG11
 guanine nucleotide binding protein (G protein), gamma 11
 1392
 0.38
chr6_82707021_82707202 0.52 ENSG00000223044
 .
 213046
 0.02
chr10_124253467_124253937 0.52 HTRA1
 HtrA serine peptidase 1
 12505
 0.2
chr1_33876024_33876604 0.52 PHC2
 polyhomeotic homolog 2 (Drosophila)
 19902
 0.15
chr5_16933613_16934070 0.52 MYO10
 myosin X
 2206
 0.34
chr2_164590053_164590372 0.52 FIGN
 fidgetin
 2305
 0.48
chr7_6296963_6297114 0.51 CYTH3
 cytohesin 3
 15237
 0.18
chr2_101437792_101437972 0.51 NPAS2
 neuronal PAS domain protein 2
 395
 0.8
chr5_66254399_66254664 0.50 MAST4
 microtubule associated serine/threonine kinase family member 4
 167
 0.97
chr4_20290565_20290748 0.50 SLIT2
 slit homolog 2 (Drosophila)
 34113
 0.23
chr15_96878465_96878729 0.49 ENSG00000222651
 .
 2107
 0.24
chr5_180212623_180213033 0.49 CTC-205M6.5
2041
 0.28
chr2_87551749_87551924 0.49 IGKV3OR2-268
 immunoglobulin kappa variable 3/OR2-268 (non-functional)
 13798
 0.29
chr18_39486579_39486788 0.48 PIK3C3
 phosphatidylinositol 3-kinase, catalytic subunit type 3
 48488
 0.2
chr12_118628413_118628612 0.48 TAOK3
 TAO kinase 3
 156
 0.96
chr14_96671190_96671644 0.48 RP11-404P21.8
 Uncharacterized protein
 236
 0.48
chr15_49717786_49717937 0.47 FGF7
 fibroblast growth factor 7
 2404
 0.35
chr11_114167265_114167463 0.47 NNMT
 nicotinamide N-methyltransferase
 721
 0.72
chr6_169651321_169651472 0.46 THBS2
 thrombospondin 2
 850
 0.72
chr2_157659750_157659995 0.46 ENSG00000263848
 .
 211897
 0.02
chr10_33620140_33620362 0.46 NRP1
 neuropilin 1
 3059
 0.34
chr5_158488903_158489314 0.46 EBF1
 early B-cell factor 1
 37593
 0.17
chr7_55141701_55142160 0.46 EGFR
 epidermal growth factor receptor
 35486
 0.22
chr15_96897591_96898313 0.46 AC087477.1
 Uncharacterized protein
 6535
 0.18
chr16_4424352_4424847 0.46 VASN
 vasorin
 2750
 0.17
chr3_112354153_112354320 0.46 CCDC80
 coiled-coil domain containing 80
 2708
 0.34
chr4_166794189_166794587 0.46 TLL1
 tolloid-like 1
 22
 0.99
chr5_6159531_6159707 0.45 ENSG00000221568
 .
 47395
 0.2
chr20_34463775_34463999 0.45 ENSG00000201221
 .
 11694
 0.14
chr13_95255061_95255225 0.45 GPR180
 G protein-coupled receptor 180
 986
 0.56
chr5_149534173_149534381 0.45 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 913
 0.52
chr1_224075422_224075812 0.45 TP53BP2
 tumor protein p53 binding protein, 2
 41943
 0.17
chr2_113379593_113379854 0.45 SLC20A1
 solute carrier family 20 (phosphate transporter), member 1
 23711
 0.15
chrX_65857072_65857466 0.45 EDA2R
 ectodysplasin A2 receptor
 1614
 0.5
chr4_151600832_151601026 0.45 ENSG00000221235
 .
 39911
 0.19
chr3_88191159_88191414 0.45 ZNF654
 zinc finger protein 654
 3032
 0.24
chr6_116550687_116550852 0.45 RP3-486I3.5
15122
 0.15
chr17_38440207_38440497 0.44 CDC6
 cell division cycle 6
 3533
 0.16
chr15_60684685_60685107 0.44 ANXA2
 annexin A2
 1400
 0.54
chr5_97790939_97791149 0.44 ENSG00000223053
 .
 183891
 0.03
chr6_18053801_18053981 0.44 KIF13A
 kinesin family member 13A
 66037
 0.11
chr12_8147555_8147963 0.44 ENSG00000206636
 .
 18904
 0.14
chr4_48701412_48701950 0.44 FRYL
 FRY-like
 18493
 0.24
chr4_23890359_23890765 0.44 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
 1096
 0.66
chr2_238321225_238321570 0.44 COL6A3
 collagen, type VI, alpha 3
 1394
 0.45
chr1_98514169_98514606 0.44 ENSG00000225206
 .
 2660
 0.42
chr16_83847696_83847847 0.44 HSBP1
 heat shock factor binding protein 1
 6177
 0.18
chr5_150153790_150154104 0.43 SMIM3
 small integral membrane protein 3
 3561
 0.18
chr7_116141667_116142184 0.43 CAV2
 caveolin 2
 2091
 0.24
chr17_78044749_78045392 0.43 CCDC40
 coiled-coil domain containing 40
 12346
 0.15
chr7_128380705_128380856 0.43 CALU
 calumenin
 1322
 0.31
chr11_111848673_111848997 0.43 DIXDC1
 DIX domain containing 1
 802
 0.5
chrX_281313_281835 0.43 LINC00685
 long intergenic non-protein coding RNA 685
 151
 0.97
chr2_3625481_3625934 0.42 ENSG00000252531
 .
 2453
 0.16
chr3_64172371_64172810 0.42 PRICKLE2-AS3
 PRICKLE2 antisense RNA 3
 630
 0.74
chr10_69865396_69865547 0.42 MYPN
 myopalladin
 441
 0.84
chr16_51573277_51573428 0.42 ENSG00000223168
 .
 132122
 0.06
chr4_122616322_122616745 0.42 ANXA5
 annexin A5
 1584
 0.45
chr18_30310087_30311054 0.42 AC012123.1
 Uncharacterized protein
 39188
 0.17
chrX_11456470_11456766 0.42 ARHGAP6
 Rho GTPase activating protein 6
 10725
 0.3
chr1_116314334_116314544 0.42 CASQ2
 calsequestrin 2 (cardiac muscle)
 3037
 0.34
chr7_13985407_13985644 0.41 ETV1
 ets variant 1
 40541
 0.2
chr2_203880731_203880966 0.41 NBEAL1
 neurobeachin-like 1
 1246
 0.53
chr3_64674138_64674393 0.41 ADAMTS9
 ADAM metallopeptidase with thrombospondin type 1 motif, 9
 589
 0.78
chr3_73672725_73672876 0.41 PDZRN3-AS1
 PDZRN3 antisense RNA 1
 81
 0.96
chr12_62998637_62998788 0.41 ENSG00000199179
 .
 1246
 0.3
chr17_45698884_45699286 0.41 NPEPPS
 aminopeptidase puromycin sensitive
 3369
 0.19
chr8_107071752_107071924 0.41 ENSG00000251003
 .
 833
 0.76
chr5_57368325_57368559 0.41 ENSG00000238899
 .
 2427
 0.45
chr5_144624994_144625233 0.41 ENSG00000221467
 .
 47775
 0.2
chr14_89020333_89020536 0.40 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
 643
 0.64
chr7_92381446_92381634 0.40 ENSG00000206763
 .
 50412
 0.14
chr7_95402477_95402695 0.40 DYNC1I1
 dynein, cytoplasmic 1, intermediate chain 1
 670
 0.81
chr2_44843789_44843940 0.40 ENSG00000252896
 .
 165405
 0.04
chr11_131782264_131782415 0.40 NTM
 neurotrimin
 977
 0.63
chr8_24867792_24867943 0.40 CTD-2168K21.2
53732
 0.14
chr9_124846791_124846942 0.40 TTLL11
 tubulin tyrosine ligase-like family, member 11
 9019
 0.2
chr7_98970111_98970529 0.40 ARPC1B
 actin related protein 2/3 complex, subunit 1B, 41kDa
 1552
 0.28
chr3_115596359_115596545 0.40 ENSG00000243359
 .
 39737
 0.22
chrY_231310_231809 0.40 NA
 NA
 > 106
 NA
chr8_13132829_13133895 0.40 DLC1
 deleted in liver cancer 1
 693
 0.78
chr7_94029901_94030156 0.40 COL1A2
 collagen, type I, alpha 2
 6155
 0.29
chr7_55509277_55509428 0.40 VOPP1
 vesicular, overexpressed in cancer, prosurvival protein 1
 74418
 0.1
chr2_235862821_235863118 0.39 SH3BP4
 SH3-domain binding protein 4
 2249
 0.48
chr5_34486658_34486809 0.39 RAI14
 retinoic acid induced 14
 169609
 0.03
chr3_192288719_192288870 0.39 ENSG00000238902
 .
 36893
 0.17
chr2_3626466_3626991 0.39 ENSG00000252531
 .
 1432
 0.27
chr15_57510230_57510387 0.39 TCF12
 transcription factor 12
 1320
 0.57
chr4_108817732_108818165 0.39 SGMS2
 sphingomyelin synthase 2
 2544
 0.25
chr9_133656541_133656767 0.39 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 53799
 0.13
chr5_52333250_52333558 0.39 CTD-2175A23.1
47296
 0.12
chr17_5085116_5085307 0.39 ZNF594
 zinc finger protein 594
 2481
 0.2
chr13_38172411_38172686 0.39 POSTN
 periostin, osteoblast specific factor
 315
 0.95
chr6_1613704_1614304 0.39 FOXC1
 forkhead box C1
 3323
 0.37
chr7_13960202_13960381 0.39 ETV1
 ets variant 1
 65775
 0.14
chr9_113680727_113680998 0.39 ENSG00000206923
 .
 15245
 0.21
chr3_98616068_98616219 0.39 DCBLD2
 discoidin, CUB and LCCL domain containing 2
 3872
 0.21
chr8_119963118_119963285 0.39 TNFRSF11B
 tumor necrosis factor receptor superfamily, member 11b
 1238
 0.55
chr2_228028292_228028853 0.39 COL4A4
 collagen, type IV, alpha 4
 257
 0.8
chr1_217263352_217263815 0.38 ESRRG
 estrogen-related receptor gamma
 607
 0.86
chr19_47693302_47693593 0.38 ENSG00000265134
 .
 36752
 0.11
chr2_110538678_110538908 0.38 RGPD5
 RANBP2-like and GRIP domain containing 5
 11542
 0.27
chr21_38035564_38035846 0.38 SIM2
 single-minded family bHLH transcription factor 2
 35729
 0.16
chr9_96902091_96902301 0.38 ENSG00000199165
 .
 36038
 0.13
chr19_13906290_13907522 0.38 ZSWIM4
 zinc finger, SWIM-type containing 4
 632
 0.39
chr8_49831970_49832121 0.38 SNAI2
 snail family zinc finger 2
 1943
 0.49
chr10_4284780_4284931 0.38 ENSG00000207124
 .
 272289
 0.02
chr7_94029074_94029225 0.38 COL1A2
 collagen, type I, alpha 2
 5276
 0.3
chr4_129292742_129292893 0.38 PGRMC2
 progesterone receptor membrane component 2
 82833
 0.11
chr7_18550262_18550413 0.38 HDAC9
 histone deacetylase 9
 1401
 0.57
chr2_9348603_9349207 0.37 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 2011
 0.46
chr7_93925885_93926036 0.37 COL1A2
 collagen, type I, alpha 2
 97913
 0.08
chr12_95597108_95597270 0.37 FGD6
 FYVE, RhoGEF and PH domain containing 6
 13966
 0.18
chr22_35778076_35778227 0.37 HMOX1
 heme oxygenase (decycling) 1
 1323
 0.43
chr13_24121751_24121902 0.37 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 22683
 0.26
chr17_2075729_2075982 0.37 SMG6
 SMG6 nonsense mediated mRNA decay factor
 617
 0.64
chr1_47778566_47778731 0.37 STIL
 SCL/TAL1 interrupting locus
 159
 0.95
chr8_37556496_37556710 0.37 ZNF703
 zinc finger protein 703
 3334
 0.17
chr18_10455593_10455868 0.37 APCDD1
 adenomatosis polyposis coli down-regulated 1
 751
 0.75
chr3_111480072_111480300 0.37 PHLDB2
 pleckstrin homology-like domain, family B, member 2
 28842
 0.2
chr7_78399800_78400051 0.36 MAGI2
 membrane associated guanylate kinase, WW and PDZ domain containing 2
 471
 0.9
chr1_238753523_238753674 0.36 ENSG00000252371
 .
 264510
 0.02
chr10_32097535_32097689 0.36 ARHGAP12
 Rho GTPase activating protein 12
 45496
 0.17
chr2_36583449_36584760 0.36 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 490
 0.89
chr3_126113468_126113707 0.36 RP11-71E19.5
107
 0.63
chr20_19957293_19957444 0.36 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 40392
 0.16
chr7_47640510_47640989 0.36 TNS3
 tensin 3
 18593
 0.25
chr22_25348691_25349626 0.36 KIAA1671
 KIAA1671
 461
 0.83
chr4_77704559_77704807 0.36 RP11-359D14.3
18434
 0.19
chr22_39801646_39801840 0.36 TAB1
 TGF-beta activated kinase 1/MAP3K7 binding protein 1
 5954
 0.16
chr4_120614315_120614472 0.36 PDE5A
 phosphodiesterase 5A, cGMP-specific
 64247
 0.13
chr1_226521053_226521239 0.35 ENSG00000239094
 .
 17281
 0.16
chr13_44404357_44404508 0.35 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 43388
 0.15
chr16_53086342_53086851 0.35 RP11-467J12.4
189
 0.95
chr3_185825097_185825248 0.35 ETV5
 ets variant 5
 1161
 0.55
chr17_79315981_79316442 0.35 TMEM105
 transmembrane protein 105
 11737
 0.13
chr19_47366981_47367578 0.35 AP2S1
 adaptor-related protein complex 2, sigma 1 subunit
 13030
 0.17
chr16_3241653_3241969 0.35 AJ003147.9
3599
 0.12
chrX_133681520_133681671 0.35 ENSG00000223749
 .
 854
 0.38
chr2_189846006_189846157 0.35 ENSG00000221502
 .
 3263
 0.28
chr8_93107061_93107485 0.35 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 170
 0.98
chr10_10872293_10872444 0.35 CELF2
 CUGBP, Elav-like family member 2
 174891
 0.03
chr15_90197878_90198651 0.35 KIF7
 kinesin family member 7
 418
 0.77
chr5_54455785_54456014 0.35 GPX8
 glutathione peroxidase 8 (putative)
 47
 0.96
chr1_61550818_61550969 0.35 ENSG00000263380
 .
 1691
 0.36
chr8_62623308_62623479 0.35 ASPH
 aspartate beta-hydroxylase
 3691
 0.27
chr4_126289975_126290162 0.35 ENSG00000201297
 .
 6094
 0.28
chr20_11524560_11524790 0.35 ENSG00000222281
 .
 275064
 0.02
chr15_89533182_89533333 0.35 ENSG00000265866
 .
 17574
 0.2
chr3_58258156_58258366 0.35 RPP14
 ribonuclease P/MRP 14kDa subunit
 33728
 0.14
chr11_107881564_107881715 0.35 CUL5
 cullin 5
 2180
 0.34
chr5_98107570_98107721 0.35 RGMB-AS1
 RGMB antisense RNA 1
 837
 0.59
chr4_153272766_153273041 0.35 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
 1220
 0.52
chr9_16867910_16868386 0.34 BNC2
 basonuclin 2
 2556
 0.42
chr11_122045636_122045787 0.34 ENSG00000207994
 .
 22695
 0.16
chr2_197831476_197831662 0.34 ANKRD44
 ankyrin repeat domain 44
 33657
 0.18
chr14_53416235_53416562 0.34 FERMT2
 fermitin family member 2
 888
 0.69
chr1_202508681_202509081 0.34 ENSG00000253042
 .
 12326
 0.21
chr12_15490173_15490332 0.34 RERG
 RAS-like, estrogen-regulated, growth inhibitor
 11280
 0.23
chr6_21886579_21886878 0.34 ENSG00000222515
 .
 199045
 0.03
chr10_92679821_92679972 0.34 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
 1137
 0.46
chr9_35907347_35908019 0.34 HRCT1
 histidine rich carboxyl terminus 1
 1494
 0.3
chr3_170625035_170625186 0.34 EIF5A2
 eukaryotic translation initiation factor 5A2
 1277
 0.5
chr3_57545487_57545638 0.34 PDE12
 phosphodiesterase 12
 3558
 0.13
chr7_42974061_42974212 0.34 PSMA2
 proteasome (prosome, macropain) subunit, alpha type, 2
 2314
 0.27

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0043589 skin morphogenesis(GO:0043589)
0.3 0.5 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.2 0.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.6 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.2 0.6 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.2 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 0.7 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.2 0.2 GO:1902692 regulation of neuroblast proliferation(GO:1902692)
0.1 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.6 GO:0014029 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.1 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.6 GO:0016264 gap junction assembly(GO:0016264)
0.1 0.4 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.4 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.3 GO:0060676 ureteric bud formation(GO:0060676)
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.3 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.7 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.2 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.4 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.2 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.4 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.1 GO:0031223 auditory behavior(GO:0031223)
0.1 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.3 GO:0010665 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.1 0.2 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.3 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.5 GO:0007567 parturition(GO:0007567)
0.1 0.5 GO:0099518 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.1 0.1 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.4 GO:0030903 notochord development(GO:0030903)
0.1 0.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0 0.5 GO:0043113 receptor clustering(GO:0043113)
0.0 0.2 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.0 GO:0051940 regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.1 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:0051299 centrosome separation(GO:0051299)
0.0 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0002604 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0 0.2 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.7 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.4 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0046040 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 2.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.4 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.4 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.0 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0061217 regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.5 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.0 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.5 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0010611 regulation of cardiac muscle hypertrophy(GO:0010611)
0.0 0.1 GO:1903393 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.8 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:0090197 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.0 GO:0030202 heparin metabolic process(GO:0030202)
0.0 0.1 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.0 GO:0090037 regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.0 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0051590 positive regulation of neurotransmitter transport(GO:0051590)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.0 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.1 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0071688 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0060044 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.0 GO:0015824 proline transport(GO:0015824)
0.0 0.0 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.0 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.2 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0000718 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.0 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.1 GO:0070875 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.0 0.1 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.3 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 1.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.6 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.4 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.4 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 2.9 GO:0030016 myofibril(GO:0030016)
0.0 0.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 1.5 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 4.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.8 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 0.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.4 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.5 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.3 GO:0042805 actinin binding(GO:0042805)
0.1 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.3 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 2.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.0 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.0 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.6 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.1 PID SHP2 PATHWAY SHP2 signaling
0.0 0.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.1 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.0 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones