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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for DUXA

Z-value: 2.01

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Transcription factors associated with DUXA

Gene Symbol	Gene ID	Gene Info
DUXA Ensembl NCBI GeneCards UniProt	ENSG00000258873.2	DUXA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
DUXA	chr19_57684363_57684522	5631	0.134985	0.39	2.9e-01	Click!
DUXA	chr19_57683645_57683950	4986	0.139304	-0.11	7.7e-01	Click!
DUXA	chr19_57682857_57683287	4261	0.146362	0.10	7.9e-01	Click!

Activity of the DUXA motif across conditions

Conditions sorted by the z-value of the DUXA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_157749235_157750071	0.92	ENSG00000263848	.	122116	0.06
chr14_86001323_86001474	0.81	FLRT2	fibronectin leucine rich transmembrane protein 2	4826	0.27
chr5_53753293_53753597	0.80	HSPB3	heat shock 27kDa protein 3	2000	0.44
chr16_54968513_54968925	0.80	IRX5	iroquois homeobox 5	2735	0.43
chr6_12573314_12573545	0.74	PHACTR1	phosphatase and actin regulator 1	144464	0.05
chr17_29888799_29888950	0.73	ENSG00000207614	.	1859	0.19
chr5_24644888_24645378	0.70	CDH10	cadherin 10, type 2 (T2-cadherin)	46	0.99
chr11_131780111_131780399	0.67	NTM	neurotrimin	642	0.77
chr2_38265076_38265999	0.66	RMDN2-AS1	RMDN2 antisense RNA 1	2053	0.33
chr15_37179413_37179956	0.66	ENSG00000212511	.	34843	0.22
chr4_81192022_81192173	0.65	FGF5	fibroblast growth factor 5	4304	0.29
chr1_165665531_165665807	0.64	ALDH9A1	aldehyde dehydrogenase 9 family, member A1	1876	0.34
chr20_43970794_43971114	0.63	SDC4	syndecan 4	6110	0.13
chr4_86700524_86700675	0.62	ARHGAP24	Rho GTPase activating protein 24	740	0.76
chr8_49831086_49831370	0.62	SNAI2	snail family zinc finger 2	2760	0.41
chr5_111090218_111090459	0.62	NREP	neuronal regeneration related protein	1610	0.42
chr8_70406794_70407007	0.62	SULF1	sulfatase 1	1872	0.5
chr3_66139685_66140118	0.61	SLC25A26	solute carrier family 25 (S-adenosylmethionine carrier), member 26	20616	0.25
chr6_152701576_152701930	0.60	SYNE1-AS1	SYNE1 antisense RNA 1	72	0.97
chr17_67137246_67137397	0.58	ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6	694	0.69
chr6_169653692_169653887	0.58	THBS2	thrombospondin 2	350	0.92
chr3_175389807_175390608	0.57	ENSG00000201648	.	62940	0.12
chr5_102202832_102203172	0.57	PAM	peptidylglycine alpha-amidating monooxygenase	1182	0.66
chr22_46462951_46463814	0.57	RP6-109B7.4		2389	0.16
chr3_149371362_149371801	0.56	WWTR1-AS1	WWTR1 antisense RNA 1	3226	0.2
chr9_21688149_21688723	0.55	ENSG00000244230	.	10877	0.24
chr3_114343007_114343163	0.55	ZBTB20	zinc finger and BTB domain containing 20	32	0.99
chr12_78336292_78336638	0.54	NAV3	neuron navigator 3	23591	0.28
chr20_56706361_56706780	0.54	C20orf85	chromosome 20 open reading frame 85	19390	0.21
chr1_68297324_68297475	0.54	GNG12-AS1	GNG12 antisense RNA 1	587	0.71
chr13_110957949_110958238	0.53	COL4A2	collagen, type IV, alpha 2	66	0.97
chr11_122072907_122073271	0.53	ENSG00000207994	.	50073	0.12
chr21_32715523_32716836	0.53	TIAM1	T-cell lymphoma invasion and metastasis 1	415	0.91
chr2_65889672_65889956	0.53	ENSG00000265899	.	4576	0.32
chr4_54213222_54213526	0.53	SCFD2	sec1 family domain containing 2	18854	0.21
chr7_93552303_93552503	0.52	GNG11	guanine nucleotide binding protein (G protein), gamma 11	1392	0.38
chr6_82707021_82707202	0.52	ENSG00000223044	.	213046	0.02
chr10_124253467_124253937	0.52	HTRA1	HtrA serine peptidase 1	12505	0.2
chr1_33876024_33876604	0.52	PHC2	polyhomeotic homolog 2 (Drosophila)	19902	0.15
chr5_16933613_16934070	0.52	MYO10	myosin X	2206	0.34
chr2_164590053_164590372	0.52	FIGN	fidgetin	2305	0.48
chr7_6296963_6297114	0.51	CYTH3	cytohesin 3	15237	0.18
chr2_101437792_101437972	0.51	NPAS2	neuronal PAS domain protein 2	395	0.8
chr5_66254399_66254664	0.50	MAST4	microtubule associated serine/threonine kinase family member 4	167	0.97
chr4_20290565_20290748	0.50	SLIT2	slit homolog 2 (Drosophila)	34113	0.23
chr15_96878465_96878729	0.49	ENSG00000222651	.	2107	0.24
chr5_180212623_180213033	0.49	CTC-205M6.5		2041	0.28
chr2_87551749_87551924	0.49	IGKV3OR2-268	immunoglobulin kappa variable 3/OR2-268 (non-functional)	13798	0.29
chr18_39486579_39486788	0.48	PIK3C3	phosphatidylinositol 3-kinase, catalytic subunit type 3	48488	0.2
chr12_118628413_118628612	0.48	TAOK3	TAO kinase 3	156	0.96
chr14_96671190_96671644	0.48	RP11-404P21.8	Uncharacterized protein	236	0.48
chr15_49717786_49717937	0.47	FGF7	fibroblast growth factor 7	2404	0.35
chr11_114167265_114167463	0.47	NNMT	nicotinamide N-methyltransferase	721	0.72
chr6_169651321_169651472	0.46	THBS2	thrombospondin 2	850	0.72
chr2_157659750_157659995	0.46	ENSG00000263848	.	211897	0.02
chr10_33620140_33620362	0.46	NRP1	neuropilin 1	3059	0.34
chr5_158488903_158489314	0.46	EBF1	early B-cell factor 1	37593	0.17
chr7_55141701_55142160	0.46	EGFR	epidermal growth factor receptor	35486	0.22
chr15_96897591_96898313	0.46	AC087477.1	Uncharacterized protein	6535	0.18
chr16_4424352_4424847	0.46	VASN	vasorin	2750	0.17
chr3_112354153_112354320	0.46	CCDC80	coiled-coil domain containing 80	2708	0.34
chr4_166794189_166794587	0.46	TLL1	tolloid-like 1	22	0.99
chr5_6159531_6159707	0.45	ENSG00000221568	.	47395	0.2
chr20_34463775_34463999	0.45	ENSG00000201221	.	11694	0.14
chr13_95255061_95255225	0.45	GPR180	G protein-coupled receptor 180	986	0.56
chr5_149534173_149534381	0.45	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	913	0.52
chr1_224075422_224075812	0.45	TP53BP2	tumor protein p53 binding protein, 2	41943	0.17
chr2_113379593_113379854	0.45	SLC20A1	solute carrier family 20 (phosphate transporter), member 1	23711	0.15
chrX_65857072_65857466	0.45	EDA2R	ectodysplasin A2 receptor	1614	0.5
chr4_151600832_151601026	0.45	ENSG00000221235	.	39911	0.19
chr3_88191159_88191414	0.45	ZNF654	zinc finger protein 654	3032	0.24
chr6_116550687_116550852	0.45	RP3-486I3.5		15122	0.15
chr17_38440207_38440497	0.44	CDC6	cell division cycle 6	3533	0.16
chr15_60684685_60685107	0.44	ANXA2	annexin A2	1400	0.54
chr5_97790939_97791149	0.44	ENSG00000223053	.	183891	0.03
chr6_18053801_18053981	0.44	KIF13A	kinesin family member 13A	66037	0.11
chr12_8147555_8147963	0.44	ENSG00000206636	.	18904	0.14
chr4_48701412_48701950	0.44	FRYL	FRY-like	18493	0.24
chr4_23890359_23890765	0.44	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	1096	0.66
chr2_238321225_238321570	0.44	COL6A3	collagen, type VI, alpha 3	1394	0.45
chr1_98514169_98514606	0.44	ENSG00000225206	.	2660	0.42
chr16_83847696_83847847	0.44	HSBP1	heat shock factor binding protein 1	6177	0.18
chr5_150153790_150154104	0.43	SMIM3	small integral membrane protein 3	3561	0.18
chr7_116141667_116142184	0.43	CAV2	caveolin 2	2091	0.24
chr17_78044749_78045392	0.43	CCDC40	coiled-coil domain containing 40	12346	0.15
chr7_128380705_128380856	0.43	CALU	calumenin	1322	0.31
chr11_111848673_111848997	0.43	DIXDC1	DIX domain containing 1	802	0.5
chrX_281313_281835	0.43	LINC00685	long intergenic non-protein coding RNA 685	151	0.97
chr2_3625481_3625934	0.42	ENSG00000252531	.	2453	0.16
chr3_64172371_64172810	0.42	PRICKLE2-AS3	PRICKLE2 antisense RNA 3	630	0.74
chr10_69865396_69865547	0.42	MYPN	myopalladin	441	0.84
chr16_51573277_51573428	0.42	ENSG00000223168	.	132122	0.06
chr4_122616322_122616745	0.42	ANXA5	annexin A5	1584	0.45
chr18_30310087_30311054	0.42	AC012123.1	Uncharacterized protein	39188	0.17
chrX_11456470_11456766	0.42	ARHGAP6	Rho GTPase activating protein 6	10725	0.3
chr1_116314334_116314544	0.42	CASQ2	calsequestrin 2 (cardiac muscle)	3037	0.34
chr7_13985407_13985644	0.41	ETV1	ets variant 1	40541	0.2
chr2_203880731_203880966	0.41	NBEAL1	neurobeachin-like 1	1246	0.53
chr3_64674138_64674393	0.41	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	589	0.78
chr3_73672725_73672876	0.41	PDZRN3-AS1	PDZRN3 antisense RNA 1	81	0.96
chr12_62998637_62998788	0.41	ENSG00000199179	.	1246	0.3
chr17_45698884_45699286	0.41	NPEPPS	aminopeptidase puromycin sensitive	3369	0.19
chr8_107071752_107071924	0.41	ENSG00000251003	.	833	0.76
chr5_57368325_57368559	0.41	ENSG00000238899	.	2427	0.45
chr5_144624994_144625233	0.41	ENSG00000221467	.	47775	0.2
chr14_89020333_89020536	0.40	PTPN21	protein tyrosine phosphatase, non-receptor type 21	643	0.64
chr7_92381446_92381634	0.40	ENSG00000206763	.	50412	0.14
chr7_95402477_95402695	0.40	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	670	0.81
chr2_44843789_44843940	0.40	ENSG00000252896	.	165405	0.04
chr11_131782264_131782415	0.40	NTM	neurotrimin	977	0.63
chr8_24867792_24867943	0.40	CTD-2168K21.2		53732	0.14
chr9_124846791_124846942	0.40	TTLL11	tubulin tyrosine ligase-like family, member 11	9019	0.2
chr7_98970111_98970529	0.40	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	1552	0.28
chr3_115596359_115596545	0.40	ENSG00000243359	.	39737	0.22
chrY_231310_231809	0.40	NA	NA	> 10⁶	NA
chr8_13132829_13133895	0.40	DLC1	deleted in liver cancer 1	693	0.78
chr7_94029901_94030156	0.40	COL1A2	collagen, type I, alpha 2	6155	0.29
chr7_55509277_55509428	0.40	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	74418	0.1
chr2_235862821_235863118	0.39	SH3BP4	SH3-domain binding protein 4	2249	0.48
chr5_34486658_34486809	0.39	RAI14	retinoic acid induced 14	169609	0.03
chr3_192288719_192288870	0.39	ENSG00000238902	.	36893	0.17
chr2_3626466_3626991	0.39	ENSG00000252531	.	1432	0.27
chr15_57510230_57510387	0.39	TCF12	transcription factor 12	1320	0.57
chr4_108817732_108818165	0.39	SGMS2	sphingomyelin synthase 2	2544	0.25
chr9_133656541_133656767	0.39	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	53799	0.13
chr5_52333250_52333558	0.39	CTD-2175A23.1		47296	0.12
chr17_5085116_5085307	0.39	ZNF594	zinc finger protein 594	2481	0.2
chr13_38172411_38172686	0.39	POSTN	periostin, osteoblast specific factor	315	0.95
chr6_1613704_1614304	0.39	FOXC1	forkhead box C1	3323	0.37
chr7_13960202_13960381	0.39	ETV1	ets variant 1	65775	0.14
chr9_113680727_113680998	0.39	ENSG00000206923	.	15245	0.21
chr3_98616068_98616219	0.39	DCBLD2	discoidin, CUB and LCCL domain containing 2	3872	0.21
chr8_119963118_119963285	0.39	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	1238	0.55
chr2_228028292_228028853	0.39	COL4A4	collagen, type IV, alpha 4	257	0.8
chr1_217263352_217263815	0.38	ESRRG	estrogen-related receptor gamma	607	0.86
chr19_47693302_47693593	0.38	ENSG00000265134	.	36752	0.11
chr2_110538678_110538908	0.38	RGPD5	RANBP2-like and GRIP domain containing 5	11542	0.27
chr21_38035564_38035846	0.38	SIM2	single-minded family bHLH transcription factor 2	35729	0.16
chr9_96902091_96902301	0.38	ENSG00000199165	.	36038	0.13
chr19_13906290_13907522	0.38	ZSWIM4	zinc finger, SWIM-type containing 4	632	0.39
chr8_49831970_49832121	0.38	SNAI2	snail family zinc finger 2	1943	0.49
chr10_4284780_4284931	0.38	ENSG00000207124	.	272289	0.02
chr7_94029074_94029225	0.38	COL1A2	collagen, type I, alpha 2	5276	0.3
chr4_129292742_129292893	0.38	PGRMC2	progesterone receptor membrane component 2	82833	0.11
chr7_18550262_18550413	0.38	HDAC9	histone deacetylase 9	1401	0.57
chr2_9348603_9349207	0.37	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	2011	0.46
chr7_93925885_93926036	0.37	COL1A2	collagen, type I, alpha 2	97913	0.08
chr12_95597108_95597270	0.37	FGD6	FYVE, RhoGEF and PH domain containing 6	13966	0.18
chr22_35778076_35778227	0.37	HMOX1	heme oxygenase (decycling) 1	1323	0.43
chr13_24121751_24121902	0.37	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	22683	0.26
chr17_2075729_2075982	0.37	SMG6	SMG6 nonsense mediated mRNA decay factor	617	0.64
chr1_47778566_47778731	0.37	STIL	SCL/TAL1 interrupting locus	159	0.95
chr8_37556496_37556710	0.37	ZNF703	zinc finger protein 703	3334	0.17
chr18_10455593_10455868	0.37	APCDD1	adenomatosis polyposis coli down-regulated 1	751	0.75
chr3_111480072_111480300	0.37	PHLDB2	pleckstrin homology-like domain, family B, member 2	28842	0.2
chr7_78399800_78400051	0.36	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	471	0.9
chr1_238753523_238753674	0.36	ENSG00000252371	.	264510	0.02
chr10_32097535_32097689	0.36	ARHGAP12	Rho GTPase activating protein 12	45496	0.17
chr2_36583449_36584760	0.36	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	490	0.89
chr3_126113468_126113707	0.36	RP11-71E19.5		107	0.63
chr20_19957293_19957444	0.36	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	40392	0.16
chr7_47640510_47640989	0.36	TNS3	tensin 3	18593	0.25
chr22_25348691_25349626	0.36	KIAA1671	KIAA1671	461	0.83
chr4_77704559_77704807	0.36	RP11-359D14.3		18434	0.19
chr22_39801646_39801840	0.36	TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	5954	0.16
chr4_120614315_120614472	0.36	PDE5A	phosphodiesterase 5A, cGMP-specific	64247	0.13
chr1_226521053_226521239	0.35	ENSG00000239094	.	17281	0.16
chr13_44404357_44404508	0.35	ENOX1	ecto-NOX disulfide-thiol exchanger 1	43388	0.15
chr16_53086342_53086851	0.35	RP11-467J12.4		189	0.95
chr3_185825097_185825248	0.35	ETV5	ets variant 5	1161	0.55
chr17_79315981_79316442	0.35	TMEM105	transmembrane protein 105	11737	0.13
chr19_47366981_47367578	0.35	AP2S1	adaptor-related protein complex 2, sigma 1 subunit	13030	0.17
chr16_3241653_3241969	0.35	AJ003147.9		3599	0.12
chrX_133681520_133681671	0.35	ENSG00000223749	.	854	0.38
chr2_189846006_189846157	0.35	ENSG00000221502	.	3263	0.28
chr8_93107061_93107485	0.35	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	170	0.98
chr10_10872293_10872444	0.35	CELF2	CUGBP, Elav-like family member 2	174891	0.03
chr15_90197878_90198651	0.35	KIF7	kinesin family member 7	418	0.77
chr5_54455785_54456014	0.35	GPX8	glutathione peroxidase 8 (putative)	47	0.96
chr1_61550818_61550969	0.35	ENSG00000263380	.	1691	0.36
chr8_62623308_62623479	0.35	ASPH	aspartate beta-hydroxylase	3691	0.27
chr4_126289975_126290162	0.35	ENSG00000201297	.	6094	0.28
chr20_11524560_11524790	0.35	ENSG00000222281	.	275064	0.02
chr15_89533182_89533333	0.35	ENSG00000265866	.	17574	0.2
chr3_58258156_58258366	0.35	RPP14	ribonuclease P/MRP 14kDa subunit	33728	0.14
chr11_107881564_107881715	0.35	CUL5	cullin 5	2180	0.34
chr5_98107570_98107721	0.35	RGMB-AS1	RGMB antisense RNA 1	837	0.59
chr4_153272766_153273041	0.35	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	1220	0.52
chr9_16867910_16868386	0.34	BNC2	basonuclin 2	2556	0.42
chr11_122045636_122045787	0.34	ENSG00000207994	.	22695	0.16
chr2_197831476_197831662	0.34	ANKRD44	ankyrin repeat domain 44	33657	0.18
chr14_53416235_53416562	0.34	FERMT2	fermitin family member 2	888	0.69
chr1_202508681_202509081	0.34	ENSG00000253042	.	12326	0.21
chr12_15490173_15490332	0.34	RERG	RAS-like, estrogen-regulated, growth inhibitor	11280	0.23
chr6_21886579_21886878	0.34	ENSG00000222515	.	199045	0.03
chr10_92679821_92679972	0.34	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	1137	0.46
chr9_35907347_35908019	0.34	HRCT1	histidine rich carboxyl terminus 1	1494	0.3
chr3_170625035_170625186	0.34	EIF5A2	eukaryotic translation initiation factor 5A2	1277	0.5
chr3_57545487_57545638	0.34	PDE12	phosphodiesterase 12	3558	0.13
chr7_42974061_42974212	0.34	PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	2314	0.27

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.1	GO:0043589	skin morphogenesis(GO:0043589)
0.3	0.5	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.2	0.9	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.6	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.2	0.6	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.2	0.6	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.2	0.7	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.2	GO:1902692	regulation of neuroblast proliferation(GO:1902692)
0.1	0.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.4	GO:0070932	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1	0.5	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.6	GO:0014029	neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.1	0.4	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.6	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.4	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.4	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.2	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.3	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.3	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.3	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.2	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.7	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.2	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.2	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.4	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	0.2	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.6	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.4	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.4	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.2	GO:0009822	alkaloid catabolic process(GO:0009822)
0.1	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.1	GO:0031223	auditory behavior(GO:0031223)
0.1	0.2	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.3	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.1	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.1	0.5	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.3	GO:0010665	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.2	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.2	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.1	0.2	GO:0043301	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1	0.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.2	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.3	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.4	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.3	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.1	0.8	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.2	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.5	GO:0007567	parturition(GO:0007567)
0.1	0.5	GO:0099518	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.1	0.1	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.4	GO:0030903	notochord development(GO:0030903)
0.1	0.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.2	GO:0008218	bioluminescence(GO:0008218)
0.0	0.4	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.2	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.2	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0	0.5	GO:0043113	receptor clustering(GO:0043113)
0.0	0.2	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.3	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.0	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.3	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.0	GO:0051940	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0	0.1	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.2	GO:0051299	centrosome separation(GO:0051299)
0.0	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0	0.2	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.7	GO:0008038	neuron recognition(GO:0008038)
0.0	0.0	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.2	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.4	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.2	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.2	GO:0046040	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.1	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.3	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:0031622	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	2.0	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.4	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.3	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.4	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.0	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0061217	regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0071501	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.2	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.2	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.2	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.3	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.5	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.5	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.0	GO:0071504	cellular response to heparin(GO:0071504)
0.0	0.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0019731	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.5	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0010611	regulation of cardiac muscle hypertrophy(GO:0010611)
0.0	0.1	GO:1903393	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.8	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	2.2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.3	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0048661	positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.0	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0090197	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0090037	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.0	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.0	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.0	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.0	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.0	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.1	GO:0072501	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0060044	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.0	GO:0015824	proline transport(GO:0015824)
0.0	0.0	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.0	GO:0032328	alanine transport(GO:0032328)
0.0	0.2	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.2	GO:0000718	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	0.1	GO:0070875	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.0	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.0	0.1	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.3	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	1.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0071942	XPC complex(GO:0071942)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.3	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.6	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	1.0	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.4	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.4	GO:0043034	costamere(GO:0043034)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.8	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0030686	90S preribosome(GO:0030686)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.4	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	2.9	GO:0030016	myofibril(GO:0030016)
0.0	0.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	1.3	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	1.5	GO:0030426	growth cone(GO:0030426)
0.0	0.3	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.8	GO:0016459	myosin complex(GO:0016459)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	4.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.2	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.3	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.8	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.9	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.5	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.3	GO:0034704	calcium channel complex(GO:0034704)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.7	GO:0016842	amidine-lyase activity(GO:0016842)
0.2	0.7	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	0.5	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.4	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.5	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.8	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.4	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.4	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	1.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.7	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.4	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.5	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.6	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	1.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.3	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.5	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.5	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.3	GO:0042805	actinin binding(GO:0042805)
0.1	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.7	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.6	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.3	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.5	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.2	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.5	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.3	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	2.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.3	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	1.1	GO:0005518	collagen binding(GO:0005518)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.3	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.4	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.3	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.2	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	2.0	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.4	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.2	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0016918	retinal binding(GO:0016918)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.0	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.0	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.0	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.0	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	3.3	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	2.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.3	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	2.6	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.1	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.0	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.0	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.1	3.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.7	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	1.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.1	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	1.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.0	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones