Project

ENCODE: H3K4me3 ChIP-Seq of primary human cells

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for E2F4

Z-value: 0.84

Motif logo

Transcription factors associated with E2F4

Gene Symbol	Gene ID	Gene Info
E2F4 Ensembl NCBI GeneCards UniProt	ENSG00000205250.4	E2F4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
E2F4	chr16_67227932_67228083	848	0.306548	0.16	6.8e-01	Click!
E2F4	chr16_67226442_67227225	761	0.343028	-0.13	7.4e-01	Click!
E2F4	chr16_67226195_67226432	241	0.774486	0.08	8.4e-01	Click!
E2F4	chr16_67225776_67226012	178	0.831564	0.01	9.8e-01	Click!

Activity of the E2F4 motif across conditions

Conditions sorted by the z-value of the E2F4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_99729815_99730045	0.56	AL109767.1		645	0.75
chr1_91966366_91967474	0.42	CDC7	cell division cycle 7	225	0.96
chr1_111888607_111889201	0.36	PIFO	primary cilia formation	6	0.97
chr17_35860978_35861129	0.33	DUSP14	dual specificity phosphatase 14	8928	0.19
chr8_1430658_1430809	0.33	DLGAP2	discs, large (Drosophila) homolog-associated protein 2	18799	0.28
chr6_391121_391497	0.32	IRF4	interferon regulatory factor 4	430	0.9
chr17_37762810_37762961	0.32	NEUROD2	neuronal differentiation 2	1311	0.34
chr2_202098878_202099103	0.28	CASP8	caspase 8, apoptosis-related cysteine peptidase	761	0.65
chrX_68047832_68048201	0.28	EFNB1	ephrin-B1	824	0.77
chrX_106448742_106449790	0.28	NUP62CL	nucleoporin 62kDa C-terminal like	397	0.61
chr3_171176844_171177618	0.28	TNIK	TRAF2 and NCK interacting kinase	621	0.77
chr13_34116896_34117047	0.27	STARD13	StAR-related lipid transfer (START) domain containing 13	192204	0.03
chr16_86542425_86542576	0.27	FOXF1	forkhead box F1	1633	0.41
chr20_2451178_2451431	0.27	SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	127	0.95
chr1_212780870_212781021	0.26	ATF3	activating transcription factor 3	1067	0.45
chr17_73105615_73105966	0.25	ARMC7	armadillo repeat containing 7	257	0.82
chr1_234040313_234040583	0.24	SLC35F3	solute carrier family 35, member F3	231	0.96
chr4_149364707_149365251	0.24	NR3C2	nuclear receptor subfamily 3, group C, member 2	871	0.75
chr5_138728866_138729168	0.24	PROB1	proline-rich basic protein 1	1868	0.18
chr19_49931395_49931706	0.24	GFY	golgi-associated, olfactory signaling regulator	4544	0.07
chr13_32889728_32890299	0.24	BRCA2	breast cancer 2, early onset	371	0.59
chr15_41199252_41199466	0.23	VPS18	vacuolar protein sorting 18 homolog (S. cerevisiae)	12694	0.11
chr19_56014942_56015267	0.23	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)	9846	0.08
chr10_79050334_79050485	0.22	RP11-328K22.1		23290	0.23
chr8_41624406_41625533	0.22	ANK1	ankyrin 1, erythrocytic	30171	0.15
chr1_155162943_155163205	0.22	MUC1	mucin 1, cell surface associated	368	0.6
chr12_69201397_69201692	0.22	MDM2	MDM2 oncogene, E3 ubiquitin protein ligase	412	0.8
chr3_51720796_51721049	0.22	ENSG00000201595	.	7676	0.15
chr11_62367040_62367191	0.22	MTA2	metastasis associated 1 family, member 2	326	0.7
chr20_30467916_30468108	0.22	TTLL9	tubulin tyrosine ligase-like family, member 9	380	0.8
chr16_68679557_68679708	0.22	CDH3	cadherin 3, type 1, P-cadherin (placental)	428	0.45
chr17_3658508_3658859	0.21	ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)	11849	0.12
chr17_35293190_35293341	0.21	RP11-445F12.1		656	0.45
chrY_16636064_16636659	0.21	NLGN4Y	neuroligin 4, Y-linked	93	0.99
chr2_128785898_128786120	0.21	SAP130	Sin3A-associated protein, 130kDa	315	0.91
chr17_38024211_38024362	0.21	ZPBP2	zona pellucida binding protein 2	131	0.95
chr17_59940229_59940941	0.21	BRIP1	BRCA1 interacting protein C-terminal helicase 1	120	0.97
chr19_50249421_50249636	0.21	TSKS	testis-specific serine kinase substrate	1107	0.28
chrX_73755392_73756724	0.20	SLC16A2	solute carrier family 16, member 2 (thyroid hormone transporter)	15103	0.23
chr11_34379895_34380202	0.20	ABTB2	ankyrin repeat and BTB (POZ) domain containing 2	493	0.86
chr11_726415_726634	0.20	AP006621.9		523	0.57
chr2_10184175_10184326	0.20	KLF11	Kruppel-like factor 11	52	0.96
chr20_2820909_2821269	0.20	PCED1A	PC-esterase domain containing 1A	228	0.52
chr13_22248486_22248637	0.20	FGF9	fibroblast growth factor 9	3039	0.33
chr17_70118144_70118357	0.20	SOX9	SRY (sex determining region Y)-box 9	1089	0.67
chr1_47899465_47899709	0.20	FOXD2-AS1	FOXD2 antisense RNA 1 (head to head)	726	0.57
chr11_1567498_1567649	0.19	DUSP8	dual specificity phosphatase 8	19593	0.12
chr1_6550194_6550563	0.19	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	252	0.87
chr20_62272433_62273064	0.19	STMN3	stathmin-like 3	11371	0.09
chr19_38701881_38702032	0.19	ENSG00000266428	.	11082	0.1
chr17_58469595_58469783	0.19	USP32	ubiquitin specific peptidase 32	80	0.53
chr5_140997925_140998467	0.19	AC008781.7		215	0.56
chr14_92588238_92588992	0.19	CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	299	0.54
chr1_26947517_26947992	0.19	ENSG00000238316	.	21126	0.12
chrX_70837224_70837375	0.19	CXCR3	chemokine (C-X-C motif) receptor 3	1061	0.51
chr2_157198349_157198757	0.19	NR4A2	nuclear receptor subfamily 4, group A, member 2	307	0.93
chr1_4716023_4716174	0.19	AJAP1	adherens junctions associated protein 1	993	0.73
chrY_15815919_15816489	0.19	TMSB4Y	thymosin beta 4, Y-linked	757	0.72
chr14_94254776_94255139	0.18	PRIMA1	proline rich membrane anchor 1	130	0.98
chrX_1780511_1780662	0.18	ASMT	acetylserotonin O-methyltransferase	25295	0.22
chr17_19015403_19015696	0.18	ENSG00000262202	.	400	0.71
chr16_68270253_68270605	0.18	ESRP2	epithelial splicing regulatory protein 2	58	0.91
chr11_777311_777493	0.18	PDDC1	Parkinson disease 7 domain containing 1	69	0.63
chr17_35165532_35165707	0.18	RP11-445F12.1		128302	0.04
chr7_100202948_100203247	0.18	PCOLCE-AS1	PCOLCE antisense RNA 1	1268	0.23
chrY_1730510_1730661	0.18	ENSG00000251841	.	922205	0.0
chr7_560180_560411	0.18	PDGFA	platelet-derived growth factor alpha polypeptide	362	0.88
chr19_639517_639685	0.18	FGF22	fibroblast growth factor 22	294	0.79
chr17_38020283_38020945	0.18	IKZF3	IKAROS family zinc finger 3 (Aiolos)	173	0.93
chr16_30081137_30081369	0.18	ALDOA	aldolase A, fructose-bisphosphate	354	0.71
chr1_161088064_161088385	0.18	NIT1	nitrilase 1	316	0.43
chr18_28621917_28622068	0.18	DSC3	desmocollin 3	715	0.67
chr11_2812990_2813414	0.18	KCNQ1-AS1	KCNQ1 antisense RNA 1	69596	0.08
chr5_114504926_114505203	0.18	TRIM36	tripartite motif containing 36	542	0.77
chr19_46282643_46282874	0.17	DMPK	dystrophia myotonica-protein kinase	1041	0.28
chr20_21086226_21086377	0.17	ENSG00000199509	.	33414	0.2
chr7_134330596_134330773	0.17	BPGM	2,3-bisphosphoglycerate mutase	876	0.7
chr10_124909262_124909943	0.17	HMX2	H6 family homeobox 2	1964	0.29
chr16_2317895_2318079	0.17	RNPS1	RNA binding protein S1, serine-rich domain	68	0.53
chr4_159592552_159593087	0.17	C4orf46	chromosome 4 open reading frame 46	225	0.72
chr17_7791100_7791439	0.17	CHD3	chromodomain helicase DNA binding protein 3	840	0.38
chr4_154680740_154681409	0.17	RNF175	ring finger protein 175	75	0.97
chr17_36667183_36667334	0.17	ARHGAP23	Rho GTPase activating protein 23	13223	0.16
chr10_70090873_70091608	0.17	HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	592	0.65
chr14_99712277_99712758	0.17	AL109767.1		16768	0.21
chr19_49630930_49631277	0.17	PPFIA3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	28	0.94
chr1_24513240_24513925	0.17	IFNLR1	interferon, lambda receptor 1	156	0.95
chr5_109025309_109025497	0.17	MAN2A1	mannosidase, alpha, class 2A, member 1	336	0.89
chr1_11741356_11741653	0.16	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	233	0.89
chr11_111307398_111307568	0.16	RP11-794P6.3		13110	0.11
chr19_4584029_4584180	0.16	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	24284	0.09
chr1_15500593_15500744	0.16	C1orf195	chromosome 1 open reading frame 195	2855	0.29
chr1_228603625_228604274	0.16	TRIM17	tripartite motif containing 17	219	0.85
chr19_35610158_35610309	0.16	FXYD3	FXYD domain containing ion transport regulator 3	34	0.95
chr10_22726004_22726972	0.16	RP11-301N24.3		76387	0.09
chr14_99740559_99741090	0.16	BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	2963	0.29
chr2_25537366_25537517	0.16	ENSG00000221445	.	14149	0.21
chr14_91883398_91883667	0.16	CCDC88C	coiled-coil domain containing 88C	158	0.97
chr21_43513996_43514147	0.16	C21orf128	chromosome 21 open reading frame 128	14573	0.18
chr4_84255463_84255632	0.16	HPSE	heparanase	388	0.89
chr1_1241228_1241379	0.16	ACAP3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	1966	0.13
chr5_156887380_156887596	0.16	CTB-109A12.1		402	0.51
chr18_33767527_33768072	0.16	MOCOS	molybdenum cofactor sulfurase	317	0.55
chr11_64636454_64636798	0.16	EHD1	EH-domain containing 1	6512	0.1
chr19_50935416_50935771	0.15	MYBPC2	myosin binding protein C, fast type	567	0.57
chr8_135724729_135724908	0.15	ZFAT	zinc finger and AT hook domain containing	387	0.91
chr10_6161799_6162068	0.15	RBM17	RNA binding motif protein 17	14999	0.14
chr3_25706566_25706764	0.15	ENSG00000264219	.	235	0.53
chr19_49403222_49403463	0.15	NUCB1	nucleobindin 1	35	0.93
chr10_7860903_7861171	0.15	TAF3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	570	0.78
chr1_227916358_227916819	0.15	SNAP47	synaptosomal-associated protein, 47kDa	230	0.92
chr21_47743435_47743618	0.15	C21orf58	chromosome 21 open reading frame 58	245	0.71
chr9_131655035_131655246	0.15	LRRC8A	leucine rich repeat containing 8 family, member A	10359	0.11
chr11_119562021_119562172	0.15	ENSG00000199217	.	35075	0.14
chr3_134515339_134515664	0.15	EPHB1	EPH receptor B1	518	0.8
chr6_33589286_33590289	0.15	ITPR3	inositol 1,4,5-trisphosphate receptor, type 3	626	0.65
chr15_30484201_30484352	0.15	ENSG00000221785	.	47196	0.09
chr9_140210185_140210336	0.15	NRARP	NOTCH-regulated ankyrin repeat protein	13557	0.09
chr17_6927436_6927587	0.15	BCL6B	B-cell CLL/lymphoma 6, member B	715	0.38
chr5_172067951_172068128	0.15	NEURL1B	neuralized E3 ubiquitin protein ligase 1B	230	0.92
chr20_55205529_55205819	0.15	TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	264	0.9
chr19_50063668_50063821	0.15	NOSIP	nitric oxide synthase interacting protein	143	0.88
chr6_52226992_52227834	0.15	PAQR8	progestin and adipoQ receptor family member VIII	169	0.96
chr1_20811158_20811808	0.15	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1	1230	0.48
chr9_100995758_100995909	0.14	TBC1D2	TBC1 domain family, member 2	20001	0.21
chr10_92631760_92632056	0.14	RPP30	ribonuclease P/MRP 30kDa subunit	168	0.95
chr1_3388211_3388362	0.14	ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16	98	0.97
chr22_39640196_39640514	0.14	PDGFB	platelet-derived growth factor beta polypeptide	401	0.8
chr16_30365797_30366566	0.14	CD2BP2	CD2 (cytoplasmic tail) binding protein 2	74	0.93
chr2_71192167_71192590	0.14	ENSG00000241159	.	323	0.74
chr1_107682797_107683388	0.14	NTNG1	netrin G1	350	0.93
chr14_69094821_69095326	0.14	CTD-2325P2.4		89	0.98
chr19_1470719_1471158	0.14	C19orf25	chromosome 19 open reading frame 25	7958	0.07
chr11_3819249_3819602	0.14	PGAP2	post-GPI attachment to proteins 2	223	0.66
chr2_43454043_43454388	0.14	ZFP36L2	ZFP36 ring finger protein-like 2	467	0.83
chr17_75136159_75136684	0.14	SEC14L1	SEC14-like 1 (S. cerevisiae)	397	0.86
chr8_22549992_22550198	0.14	EGR3	early growth response 3	168	0.92
chr16_87160456_87160743	0.14	RP11-899L11.3		88922	0.08
chr18_43417850_43418214	0.14	SIGLEC15	sialic acid binding Ig-like lectin 15	226	0.94
chr11_2291181_2291518	0.14	ASCL2	achaete-scute family bHLH transcription factor 2	833	0.53
chr16_79844626_79844777	0.14	ENSG00000221330	.	141067	0.05
chr20_55965895_55966111	0.14	RBM38	RNA binding motif protein 38	460	0.74
chr3_30655645_30655796	0.14	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	7627	0.31
chr19_56014768_56014919	0.14	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)	9585	0.08
chr17_66016231_66016439	0.14	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	15300	0.15
chr10_23633268_23633917	0.14	C10orf67	chromosome 10 open reading frame 67	182	0.86
chr7_25902294_25902669	0.14	ENSG00000199085	.	87125	0.1
chr1_175162248_175162570	0.14	KIAA0040	KIAA0040	330	0.93
chr13_110439180_110439367	0.14	IRS2	insulin receptor substrate 2	358	0.92
chrX_101410005_101410156	0.14	BEX5	brain expressed, X-linked 5	682	0.64
chr12_113590786_113591379	0.14	CCDC42B	coiled-coil domain containing 42B	47	0.95
chr18_24128407_24128977	0.14	KCTD1	potassium channel tetramerization domain containing 1	192	0.96
chr17_66561126_66561277	0.14	AC079210.1	Uncharacterized protein; cDNA FLJ45097 fis, clone BRAWH3031054	21832	0.18
chr17_14204490_14204770	0.14	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	230	0.95
chr17_38720511_38720770	0.13	CCR7	chemokine (C-C motif) receptor 7	1071	0.49
chr13_109147564_109147910	0.13	MYO16	myosin XVI	100763	0.08
chr17_79917712_79918256	0.13	NOTUM	notum pectinacetylesterase homolog (Drosophila)	298	0.72
chr9_971958_972221	0.13	DMRT3	doublesex and mab-3 related transcription factor 3	4875	0.26
chr12_103888876_103889092	0.13	C12orf42	chromosome 12 open reading frame 42	747	0.75
chr8_145103879_145104096	0.13	CTD-3065J16.6		43	0.94
chr16_32127388_32127983	0.13	IGHV3OR16-9	immunoglobulin heavy variable 3/OR16-9 (non-functional)	50299	0.11
chr11_65360328_65360479	0.13	AP001362.1	Uncharacterized protein	456	0.42
chr8_82753589_82754405	0.13	SNX16	sorting nexin 16	196	0.96
chr4_57521556_57521858	0.13	HOPX	HOP homeobox	763	0.73
chr16_67281539_67281690	0.13	FHOD1	formin homology 2 domain containing 1	53	0.9
chr1_110198687_110199384	0.13	GSTM4	glutathione S-transferase mu 4	77	0.94
chr2_74709205_74709356	0.13	CCDC142	coiled-coil domain containing 142	843	0.25
chr6_26087484_26088662	0.13	HFE	hemochromatosis	406	0.66
chr18_657791_658473	0.13	C18orf56	chromosome 18 open reading frame 56	137	0.73
chr15_90744552_90744900	0.13	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	42	0.96
chr20_52789675_52790234	0.13	CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	234	0.95
chr7_100273526_100273689	0.13	GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	137	0.92
chr16_11038113_11038264	0.13	CLEC16A	C-type lectin domain family 16, member A	157	0.92
chr21_47410185_47410336	0.13	COL6A1	collagen, type VI, alpha 1	8609	0.21
chr12_96184496_96184659	0.13	NTN4	netrin 4	35	0.97
chr9_139428442_139428593	0.13	RP11-413M3.4		8816	0.09
chr11_279675_279826	0.13	NLRP6	NLR family, pyrin domain containing 6	1180	0.24
chr5_132083512_132083663	0.13	CCNI2	cyclin I family, member 2	450	0.75
chrX_25020829_25021251	0.13	ARX	aristaless related homeobox	13025	0.26
chr3_52479164_52479315	0.13	SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	138	0.92
chr17_7155597_7155825	0.13	ELP5	elongator acetyltransferase complex subunit 5	16	0.54
chr10_22623860_22624493	0.13	BMI1	BMI1 polycomb ring finger oncogene	8728	0.15
chr11_6341290_6341712	0.13	PRKCDBP	protein kinase C, delta binding protein	261	0.9
chr8_23145924_23146455	0.13	R3HCC1	R3H domain and coiled-coil containing 1	254	0.9
chr20_37229998_37230149	0.13	ARHGAP40	Rho GTPase activating protein 40	504	0.79
chr11_6341817_6342265	0.13	PRKCDBP	protein kinase C, delta binding protein	164	0.94
chr7_75988487_75988672	0.13	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	231	0.92
chr15_96897228_96897556	0.13	AC087477.1	Uncharacterized protein	7095	0.17
chr19_20149762_20150000	0.13	ZNF682	zinc finger protein 682	133	0.96
chr3_33759780_33760154	0.13	CLASP2	cytoplasmic linker associated protein 2	119	0.98
chr10_64576967_64577230	0.13	EGR2	early growth response 2	972	0.57
chr2_27309133_27309349	0.13	KHK	ketohexokinase (fructokinase)	374	0.67
chr1_228400994_228401320	0.13	C1orf145	chromosome 1 open reading frame 145	204	0.9
chr3_155588547_155589233	0.13	GMPS	guanine monphosphate synthase	451	0.85
chr5_156692731_156693021	0.13	CYFIP2	cytoplasmic FMR1 interacting protein 2	215	0.83
chr7_102920201_102920819	0.13	DPY19L2P2	DPY19L2 pseudogene 2	2425	0.27
chr18_24764849_24765000	0.13	CHST9	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9	338	0.94
chr8_65711600_65711819	0.13	CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	391	0.91
chr6_11233064_11233578	0.13	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	406	0.89
chr14_105144247_105144490	0.12	ENSG00000265291	.	282	0.87

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F4

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.3	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	0.2	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.5	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.1	0.2	GO:0001705	ectoderm formation(GO:0001705)
0.1	0.1	GO:0048478	replication fork protection(GO:0048478)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.1	GO:0060462	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1	0.2	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.2	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.2	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0051797	regulation of hair follicle development(GO:0051797)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.2	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.0	GO:0043096	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.3	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0021612	cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0	0.1	GO:0035625	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.3	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.2	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.0	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.0	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.2	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.2	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.2	GO:0072665	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0060119	inner ear receptor cell development(GO:0060119) inner ear receptor stereocilium organization(GO:0060122)
0.0	0.1	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.0	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.1	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0032324	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.0	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0048821	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.1	GO:0009437	amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.3	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0018216	peptidyl-arginine methylation(GO:0018216) peptidyl-arginine N-methylation(GO:0035246)
0.0	0.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.3	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.1	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.2	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0090036	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.3	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.2	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0	0.1	GO:0007143	female meiotic division(GO:0007143)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.0	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.1	GO:0048505	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.0	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.0	GO:0030540	female genitalia development(GO:0030540)
0.0	0.1	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0072162	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.0	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.2	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.1	GO:0043174	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) nucleoside salvage(GO:0043174)
0.0	0.1	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.0	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.2	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.1	GO:1903556	negative regulation of tumor necrosis factor production(GO:0032720) negative regulation of tumor necrosis factor superfamily cytokine production(GO:1903556)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.0	0.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.0	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.4	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.7	GO:0000786	nucleosome(GO:0000786)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.6	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.3	GO:0032587	ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.1	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.2	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.2	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0051379	epinephrine binding(GO:0051379)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0034618	arginine binding(GO:0034618)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.3	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.6	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.0	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.0	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.0	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.0	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0043394	proteoglycan binding(GO:0043394)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.0	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.3	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	1.3	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.2	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.0	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.3	PID S1P S1P1 PATHWAY	S1P1 pathway
0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3	PID ATR PATHWAY	ATR signaling pathway
0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.5	PID P53 REGULATION PATHWAY	p53 pathway
0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	PID IL3 PATHWAY	IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.4	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.6	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.4	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.6	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway