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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for E2F6

Z-value: 1.43

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Transcription factors associated with E2F6

Gene Symbol	Gene ID	Gene Info
E2F6 Ensembl NCBI GeneCards UniProt	ENSG00000169016.12	E2F transcription factor 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_11623432_11623724	E2F6	17303	0.131645	-0.80	9.1e-03	Click!
chr2_11605436_11606018	E2F6	278	0.871326	-0.73	2.7e-02	Click!
chr2_11604938_11605089	E2F6	992	0.374343	-0.72	2.9e-02	Click!
chr2_11622794_11623343	E2F6	16793	0.132803	-0.70	3.6e-02	Click!
chr2_11606059_11606245	E2F6	123	0.950001	-0.38	3.2e-01	Click!

Activity of the E2F6 motif across conditions

Conditions sorted by the z-value of the E2F6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_391719_392776	1.04	IRF4	interferon regulatory factor 4	508	0.87
chr20_50158730_50159057	0.94	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	365	0.92
chr5_169064267_169064974	0.90	DOCK2	dedicator of cytokinesis 2	369	0.91
chr11_63974616_63975431	0.90	FERMT3	fermitin family member 3	266	0.78
chr2_136874741_136875309	0.89	CXCR4	chemokine (C-X-C motif) receptor 4	710	0.79
chr11_64510621_64511071	0.87	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	415	0.76
chrX_109246139_109246998	0.81	TMEM164	transmembrane protein 164	225	0.95
chr15_45458687_45459673	0.81	RP11-519G16.2		3362	0.13
chr20_37434091_37434759	0.78	PPP1R16B	protein phosphatase 1, regulatory subunit 16B	58	0.98
chr4_129732983_129734245	0.75	JADE1	jade family PHD finger 1	615	0.83
chr17_36861833_36863162	0.75	CTB-58E17.3		17	0.9
chr17_56408210_56408765	0.73	MIR142	microRNA 142	192	0.87
chr11_63438034_63439177	0.71	ATL3	atlastin GTPase 3	479	0.76
chr19_3036283_3036702	0.71	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	6880	0.13
chr8_22552129_22552945	0.71	EGR3	early growth response 3	1722	0.26
chr3_36985452_36986747	0.71	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	449	0.83
chr16_88752166_88752784	0.67	SNAI3	snail family zinc finger 3	426	0.56
chr2_42721214_42722254	0.63	MTA3	metastasis associated 1 family, member 3	25	0.9
chr1_9882638_9884014	0.63	CLSTN1	calsyntenin 1	716	0.65
chr17_29036450_29037561	0.61	ENSG00000241631	.	7212	0.17
chr19_14315927_14317134	0.60	LPHN1	latrophilin 1	451	0.77
chr14_64319967_64320824	0.60	SYNE2	spectrin repeat containing, nuclear envelope 2	663	0.73
chr18_60382485_60382689	0.60	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	85	0.98
chr8_41624406_41625533	0.59	ANK1	ankyrin 1, erythrocytic	30171	0.15
chr1_160492671_160493029	0.56	SLAMF6	SLAM family member 6	182	0.92
chr10_6243545_6244657	0.56	RP11-414H17.5		555	0.52
chr1_206729975_206731239	0.56	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	114	0.96
chr12_6937518_6938631	0.54	LEPREL2	leprecan-like 2	502	0.55
chr6_41702621_41703238	0.54	TFEB	transcription factor EB	131	0.93
chr19_55850633_55850856	0.54	SUV420H2	suppressor of variegation 4-20 homolog 2 (Drosophila)	477	0.39
chrX_39949292_39950247	0.53	BCOR	BCL6 corepressor	6887	0.33
chr11_62367822_62369222	0.53	MTA2	metastasis associated 1 family, member 2	225	0.8
chr17_3866518_3867344	0.53	ATP2A3	ATPase, Ca++ transporting, ubiquitous	654	0.71
chr9_130668351_130668505	0.53	ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	819	0.4
chr18_77283391_77284187	0.52	AC018445.1	Uncharacterized protein	7732	0.29
chr2_219846787_219847191	0.51	FEV	FEV (ETS oncogene family)	3390	0.12
chr19_1067222_1068216	0.51	HMHA1	histocompatibility (minor) HA-1	222	0.85
chr15_38850039_38850247	0.51	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	2140	0.31
chr8_142425139_142425650	0.51	PTP4A3	protein tyrosine phosphatase type IVA, member 3	6613	0.14
chr6_33285429_33285580	0.50	ZBTB22	zinc finger and BTB domain containing 22	8	0.94
chr19_1019836_1021109	0.49	TMEM259	transmembrane protein 259	373	0.62
chrX_39968386_39969319	0.49	BCOR	BCL6 corepressor	12196	0.31
chr7_640710_640861	0.49	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta	1535	0.33
chr15_42867116_42867674	0.49	STARD9	StAR-related lipid transfer (START) domain containing 9	462	0.74
chr15_65578383_65579365	0.49	PARP16	poly (ADP-ribose) polymerase family, member 16	307	0.76
chr11_64512499_64513555	0.48	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	99	0.95
chr8_142215547_142216678	0.48	DENND3	DENN/MADD domain containing 3	13682	0.16
chrX_129243329_129244377	0.48	ELF4	E74-like factor 4 (ets domain transcription factor)	483	0.82
chr17_73521876_73522311	0.48	LLGL2	lethal giant larvae homolog 2 (Drosophila)	223	0.87
chr1_21619720_21620176	0.48	RP5-1071N3.1		165	0.91
chr2_43452698_43453520	0.48	ZFP36L2	ZFP36 ring finger protein-like 2	639	0.76
chr1_25255138_25255978	0.48	RUNX3	runt-related transcription factor 3	54	0.98
chr8_19354385_19354536	0.48	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	104916	0.08
chr12_56325064_56325671	0.47	DGKA	diacylglycerol kinase, alpha 80kDa	130	0.89
chr5_175665565_175666307	0.47	SIMC1	SUMO-interacting motifs containing 1	533	0.81
chr4_2418580_2419575	0.47	ZFYVE28	zinc finger, FYVE domain containing 28	1259	0.44
chr17_76164337_76165654	0.47	SYNGR2	synaptogyrin 2	244	0.87
chr9_131418722_131419532	0.46	WDR34	WD repeat domain 34	61	0.96
chr2_242786288_242786730	0.46	AC114730.2		23	0.96
chr22_20905629_20905785	0.45	MED15	mediator complex subunit 15	130	0.95
chr5_176980162_176981368	0.45	FAM193B	family with sequence similarity 193, member B	2	0.96
chr16_66638822_66640143	0.45	CMTM3	CKLF-like MARVEL transmembrane domain containing 3	58	0.95
chr11_65149415_65150138	0.45	SLC25A45	solute carrier family 25, member 45	68	0.95
chr17_75883539_75884681	0.45	FLJ45079		5451	0.25
chrX_103357104_103358067	0.44	ZCCHC18	zinc finger, CCHC domain containing 18	383	0.86
chr5_133861629_133862874	0.44	JADE2	jade family PHD finger 2	76	0.97
chr22_37881004_37881696	0.44	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	683	0.62
chr9_111774679_111775742	0.44	CTNNAL1	catenin (cadherin-associated protein), alpha-like 1	569	0.71
chrX_70837224_70837375	0.44	CXCR3	chemokine (C-X-C motif) receptor 3	1061	0.51
chr2_96990726_96991935	0.44	ITPRIPL1	inositol 1,4,5-trisphosphate receptor interacting protein-like 1	184	0.92
chr6_166721057_166722024	0.43	PRR18	proline rich 18	331	0.9
chr10_62492315_62493446	0.43	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	368	0.92
chr8_124084641_124084792	0.43	TBC1D31	TBC1 domain family, member 31	204	0.93
chr12_124941723_124942278	0.43	NCOR2	nuclear receptor corepressor 2	26315	0.25
chr8_61821706_61823076	0.43	RP11-33I11.2		100226	0.08
chr3_127391015_127391584	0.43	ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	482	0.79
chr17_46506976_46507533	0.42	SKAP1	src kinase associated phosphoprotein 1	298	0.87
chr2_25474203_25475088	0.42	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	535	0.81
chr10_88159807_88161210	0.42	GRID1	glutamate receptor, ionotropic, delta 1	34273	0.17
chr1_16163545_16164001	0.42	RP11-169K16.9		1418	0.35
chr14_23771167_23772153	0.42	PPP1R3E	protein phosphatase 1, regulatory subunit 3E	397	0.64
chr9_134147000_134147362	0.42	FAM78A	family with sequence similarity 78, member A	1271	0.44
chr2_30454378_30455881	0.42	LBH	limb bud and heart development	83	0.98
chr5_180230026_180230861	0.42	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	38	0.97
chr17_17942741_17942956	0.42	GID4	GID complex subunit 4	89	0.78
chrX_39964334_39965624	0.42	BCOR	BCL6 corepressor	8323	0.32
chr5_87970310_87970792	0.42	CTC-467M3.1		1485	0.42
chr15_41055526_41056933	0.42	GCHFR	GTP cyclohydrolase I feedback regulator	11	0.96
chr12_62585045_62586543	0.41	FAM19A2	family with sequence similarity 19 (chemokine (C-C motif)-like), member A2	577	0.8
chr19_4067333_4067959	0.41	ZBTB7A	zinc finger and BTB domain containing 7A	703	0.54
chr14_105553392_105553992	0.41	GPR132	G protein-coupled receptor 132	21910	0.17
chr6_157041219_157041750	0.41	ARID1B	AT rich interactive domain 1B (SWI1-like)	57579	0.13
chr14_105525444_105525595	0.41	GPR132	G protein-coupled receptor 132	1700	0.36
chr3_14474617_14474768	0.41	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	514	0.83
chr17_65373728_65374565	0.40	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1	125	0.95
chr22_41843038_41844299	0.40	TOB2	transducer of ERBB2, 2	641	0.64
chr3_128207705_128209147	0.40	RP11-475N22.4		326	0.79
chr21_47393002_47394285	0.40	COL6A1	collagen, type VI, alpha 1	8008	0.2
chr2_64978532_64979299	0.40	ENSG00000253082	.	24323	0.19
chr14_101193607_101193758	0.40	DLK1	delta-like 1 homolog (Drosophila)	315	0.83
chr9_139948618_139948891	0.40	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	257	0.71
chr2_171571264_171571992	0.39	SP5	Sp5 transcription factor	233	0.76
chrX_129306905_129307398	0.39	RAB33A	RAB33A, member RAS oncogene family	1528	0.4
chr17_47295344_47295579	0.39	ABI3	ABI family, member 3	1464	0.33
chr12_111843881_111845308	0.39	SH2B3	SH2B adaptor protein 3	842	0.62
chr11_65325481_65325928	0.39	LTBP3	latent transforming growth factor beta binding protein 3	5	0.94
chr16_50776136_50776713	0.39	ENSG00000264947	.	208	0.4
chr19_39108076_39108634	0.39	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	209	0.87
chr2_65283402_65284189	0.38	CEP68	centrosomal protein 68kDa	196	0.94
chr7_157368911_157369331	0.38	ENSG00000207960	.	2007	0.35
chr15_69111361_69112528	0.38	ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	1281	0.51
chr22_50919615_50920637	0.38	ADM2	adrenomedullin 2	27	0.94
chr1_234746129_234746973	0.38	IRF2BP2	interferon regulatory factor 2 binding protein 2	1280	0.44
chr16_68481793_68482359	0.38	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	319	0.87
chr3_196729783_196730213	0.38	MFI2-AS1	MFI2 antisense RNA 1	5	0.97
chr19_42391673_42391966	0.37	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	3304	0.15
chr15_91324208_91324386	0.37	ENSG00000200677	.	25755	0.13
chr7_26415747_26416790	0.37	AC004540.4		53	0.98
chr12_1905695_1906675	0.37	CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	14701	0.2
chrX_153095524_153095861	0.37	PDZD4	PDZ domain containing 4	121	0.93
chr9_92220501_92221395	0.37	GADD45G	growth arrest and DNA-damage-inducible, gamma	995	0.69
chr17_79917712_79918256	0.37	NOTUM	notum pectinacetylesterase homolog (Drosophila)	298	0.72
chr18_46478680_46479237	0.37	SMAD7	SMAD family member 7	1877	0.42
chr4_15002935_15003952	0.37	CPEB2	cytoplasmic polyadenylation element binding protein 2	855	0.74
chr10_126223246_126223402	0.36	LHPP	phospholysine phosphohistidine inorganic pyrophosphate phosphatase	72912	0.09
chr22_50688884_50689711	0.36	HDAC10	histone deacetylase 10	164	0.88
chrX_40035041_40035983	0.36	BCOR	BCL6 corepressor	1061	0.68
chr10_112327463_112328125	0.36	SMC3	structural maintenance of chromosomes 3	345	0.86
chrX_123094531_123095374	0.36	STAG2	stromal antigen 2	212	0.95
chr20_43996552_43996703	0.36	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)	4533	0.13
chr7_128578118_128579002	0.36	IRF5	interferon regulatory factor 5	289	0.89
chr9_132222382_132222610	0.36	ENSG00000264298	.	18339	0.2
chr1_25291235_25291516	0.36	RUNX3	runt-related transcription factor 3	100	0.97
chr11_60742348_60742514	0.36	CD6	CD6 molecule	3093	0.15
chr5_131745958_131747299	0.36	C5orf56	chromosome 5 open reading frame 56	45	0.96
chr16_89034541_89034870	0.36	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	8696	0.15
chr13_114893960_114894535	0.36	RASA3	RAS p21 protein activator 3	3780	0.26
chr15_102501876_102502491	0.36	WASH3P	WAS protein family homolog 3 pseudogene	363	0.8
chr5_75699014_75699893	0.36	IQGAP2	IQ motif containing GTPase activating protein 2	304	0.94
chr12_54954599_54954947	0.36	PDE1B	phosphodiesterase 1B, calmodulin-dependent	468	0.76
chr22_17567910_17568443	0.36	IL17RA	interleukin 17 receptor A	2327	0.26
chr11_64036844_64037358	0.35	GPR137	G protein-coupled receptor 137	433	0.56
chr2_241506160_241507188	0.35	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	1430	0.26
chr12_112856778_112857620	0.35	PTPN11	protein tyrosine phosphatase, non-receptor type 11	481	0.51
chr6_126069184_126070625	0.35	RP11-624M8.1		428	0.68
chrX_15767915_15768266	0.35	CA5B	carbonic anhydrase VB, mitochondrial	3	0.98
chr6_35655029_35656564	0.35	FKBP5	FK506 binding protein 5	896	0.49
chrX_40004759_40006118	0.35	BCOR	BCL6 corepressor	444	0.9
chr1_53067779_53068286	0.35	GPX7	glutathione peroxidase 7	12	0.98
chrX_44203680_44203969	0.35	EFHC2	EF-hand domain (C-terminal) containing 2	906	0.71
chr5_64331070_64331877	0.35	ENSG00000207439	.	87723	0.1
chr17_17660862_17661247	0.35	RAI1-AS1	RAI1 antisense RNA 1	13081	0.13
chr1_229478536_229478909	0.35	CCSAP	centriole, cilia and spindle-associated protein	13	0.97
chr12_111127069_111127565	0.34	HVCN1	hydrogen voltage-gated channel 1	95	0.97
chr17_61627033_61627484	0.34	DCAF7	DDB1 and CUL4 associated factor 7	564	0.68
chr2_233925207_233925694	0.34	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	261	0.92
chr19_10346719_10347362	0.34	DNMT1	DNA (cytosine-5-)-methyltransferase 1	5078	0.09
chr5_126111996_126112618	0.34	LMNB1	lamin B1	533	0.82
chr9_98784274_98784675	0.34	ERCC6L2	excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2	49355	0.15
chr1_78277295_78277520	0.34	FAM73A	family with sequence similarity 73, member A	31814	0.14
chr20_37434777_37435281	0.34	PPP1R16B	protein phosphatase 1, regulatory subunit 16B	662	0.71
chrX_153284800_153285224	0.34	IRAK1	interleukin-1 receptor-associated kinase 1	239	0.66
chr17_19015403_19015696	0.34	ENSG00000262202	.	400	0.71
chr14_52735343_52735536	0.34	PTGDR	prostaglandin D2 receptor (DP)	909	0.68
chr1_113050561_113051464	0.33	WNT2B	wingless-type MMTV integration site family, member 2B	388	0.86
chr20_62272433_62273064	0.33	STMN3	stathmin-like 3	11371	0.09
chr10_28034414_28035482	0.33	MKX	mohawk homeobox	41	0.96
chr2_106710962_106711113	0.33	C2orf40	chromosome 2 open reading frame 40	28781	0.2
chr6_137242277_137243470	0.33	SLC35D3	solute carrier family 35, member D3	529	0.78
chr4_89513596_89514242	0.33	HERC3	HECT and RLD domain containing E3 ubiquitin protein ligase 3	272	0.91
chr19_17958305_17958511	0.33	JAK3	Janus kinase 3	418	0.74
chr17_27899773_27899944	0.33	TP53I13	tumor protein p53 inducible protein 13	410	0.66
chr13_113344762_113345507	0.33	ATP11A	ATPase, class VI, type 11A	491	0.81
chr22_20003723_20004755	0.33	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	92	0.75
chr1_143913778_143914315	0.33	FAM72D	family with sequence similarity 72, member D	903	0.56
chr12_6570039_6570337	0.33	TAPBPL	TAP binding protein-like	8938	0.09
chr1_29241415_29242250	0.33	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	741	0.66
chr6_14865814_14865965	0.33	ENSG00000206960	.	219123	0.02
chr15_58358092_58358668	0.33	ALDH1A2	aldehyde dehydrogenase 1 family, member A2	236	0.88
chr15_68126396_68126860	0.32	ENSG00000206625	.	5755	0.25
chr3_155588547_155589233	0.32	GMPS	guanine monphosphate synthase	451	0.85
chr1_12227603_12227877	0.32	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	680	0.65
chr17_43298627_43299099	0.32	CTD-2020K17.1		269	0.49
chrX_149532322_149533120	0.32	MAMLD1	mastermind-like domain containing 1	1035	0.67
chr10_92923498_92924173	0.32	PCGF5	polycomb group ring finger 5	56073	0.16
chr9_123837276_123837840	0.32	CNTRL	centriolin	268	0.93
chr7_1704511_1705114	0.32	ELFN1	extracellular leucine-rich repeat and fibronectin type III domain containing 1	22943	0.17
chr2_223184639_223185184	0.32	AC010980.2		1915	0.33
chr7_17441950_17442101	0.32	ENSG00000199473	.	29075	0.23
chrX_46772292_46772991	0.32	JADE3	jade family PHD finger 3	410	0.86
chr20_25176247_25177242	0.32	ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	269	0.91
chr10_99789941_99790475	0.32	CRTAC1	cartilage acidic protein 1	377	0.91
chr5_139090263_139090939	0.31	ENSG00000200756	.	7074	0.21
chr9_117134390_117135168	0.31	AKNA	AT-hook transcription factor	4465	0.23
chr1_244012088_244013269	0.31	AKT3	v-akt murine thymoma viral oncogene homolog 3	752	0.75
chr12_113494281_113494869	0.31	DTX1	deltex homolog 1 (Drosophila)	920	0.55
chrX_133307544_133307743	0.31	ENSG00000207602	.	3335	0.12
chr8_67524543_67525469	0.31	MYBL1	v-myb avian myeloblastosis viral oncogene homolog-like 1	136	0.96
chr1_26646074_26646278	0.31	UBXN11	UBX domain protein 11	1322	0.27
chr12_121570606_121571339	0.31	P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	198	0.94

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4	0.8	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.3	1.7	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.3	0.8	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2	0.7	GO:0033622	integrin activation(GO:0033622)
0.2	0.7	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2	1.4	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.2	0.9	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.2	0.5	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.4	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.4	GO:0046931	pore complex assembly(GO:0046931)
0.1	0.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.4	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.1	0.4	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.6	GO:0060023	soft palate development(GO:0060023)
0.1	0.4	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.1	0.5	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.4	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.1	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.1	0.3	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.3	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.3	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.3	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.3	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.3	GO:0060789	hair follicle placode formation(GO:0060789)
0.1	0.2	GO:0035987	endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.1	0.3	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.5	GO:0032494	response to peptidoglycan(GO:0032494)
0.1	0.4	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1	0.2	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.3	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.4	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	1.1	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.1	0.3	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.1	0.2	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1	0.2	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.1	0.3	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.1	GO:0001787	natural killer cell proliferation(GO:0001787)
0.1	0.2	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.3	GO:0001779	natural killer cell differentiation(GO:0001779)
0.1	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.2	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.3	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.2	GO:0060242	contact inhibition(GO:0060242)
0.1	0.3	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.2	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.4	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.6	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.3	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.8	GO:0001782	B cell homeostasis(GO:0001782)
0.1	0.2	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1	0.1	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.1	0.2	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.1	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1	0.3	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	0.2	GO:0060061	Spemann organizer formation(GO:0060061)
0.1	0.5	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1	0.3	GO:0001866	NK T cell proliferation(GO:0001866)
0.1	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.1	0.3	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1	0.3	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.1	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.2	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.1	0.2	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.1	0.2	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.1	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.2	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1	1.4	GO:0030890	positive regulation of B cell proliferation(GO:0030890)
0.1	0.2	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.1	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.1	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.2	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.1	0.4	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.1	0.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.2	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.3	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.3	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	0.1	GO:0031060	regulation of histone methylation(GO:0031060)
0.1	0.3	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.2	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1	0.2	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.1	0.3	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.1	0.2	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.2	GO:0090200	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.1	0.4	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.1	0.2	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.1	0.2	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.2	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.2	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1	0.5	GO:0016601	Rac protein signal transduction(GO:0016601)
0.1	0.3	GO:0006776	vitamin A metabolic process(GO:0006776)
0.1	0.3	GO:0032613	interleukin-10 production(GO:0032613)
0.1	0.2	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.2	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.2	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.1	0.2	GO:0015825	L-serine transport(GO:0015825)
0.1	0.2	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0	0.6	GO:0010510	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.0	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.0	GO:0061054	dermatome development(GO:0061054)
0.0	0.2	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.3	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.2	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.2	GO:0021612	cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0	0.3	GO:0014002	astrocyte development(GO:0014002)
0.0	0.2	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.5	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.0	0.7	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.4	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.8	GO:0030316	osteoclast differentiation(GO:0030316)
0.0	0.1	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.2	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.2	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.2	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.3	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.3	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.0	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.2	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.5	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.7	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.1	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.3	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.3	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	0.2	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.6	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.2	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0033567	lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.2	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.2	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.1	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.2	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.3	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.0	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.0	0.1	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.2	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.1	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.2	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.7	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.2	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0070339	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.1	GO:0090199	regulation of release of cytochrome c from mitochondria(GO:0090199) regulation of apoptotic signaling pathway(GO:2001233)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0072177	mesonephric duct development(GO:0072177)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.7	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.8	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.1	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.2	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.9	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.4	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.0	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0021819	cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.3	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.6	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	1.0	GO:0034130	toll-like receptor 1 signaling pathway(GO:0034130)
0.0	0.2	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.1	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.1	GO:0021697	cerebellar cortex formation(GO:0021697)
0.0	0.4	GO:0034968	histone lysine methylation(GO:0034968)
0.0	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.0	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.3	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.2	GO:0048662	negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:1902305	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0043967	histone H4 acetylation(GO:0043967)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.0	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) regulation of signal transduction by p53 class mediator(GO:1901796)
0.0	0.0	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.0	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.0	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.2	GO:0051322	anaphase(GO:0051322)
0.0	0.3	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.0	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.3	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.0	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.3	GO:0030593	neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0	0.2	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.3	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.3	GO:0009268	response to pH(GO:0009268)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0090273	somatostatin secretion(GO:0070253) regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.0	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0031365	N-terminal protein amino acid modification(GO:0031365)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.2	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0046688	response to copper ion(GO:0046688)
0.0	0.1	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.4	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.0	0.4	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.7	GO:0006094	gluconeogenesis(GO:0006094)
0.0	0.0	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:2000644	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.0	0.2	GO:0043462	regulation of ATPase activity(GO:0043462)
0.0	0.2	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0032096	negative regulation of response to food(GO:0032096)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.3	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.2	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:1904376	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0010821	regulation of mitochondrion organization(GO:0010821)
0.0	0.0	GO:0006505	GPI anchor metabolic process(GO:0006505)
0.0	0.0	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0016139	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.6	GO:0031023	microtubule organizing center organization(GO:0031023)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.3	GO:0016236	macroautophagy(GO:0016236)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0051225	spindle assembly(GO:0051225)
0.0	0.2	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.1	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.1	GO:0000050	urea cycle(GO:0000050)
0.0	0.3	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0042921	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.1	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0032675	regulation of interleukin-6 production(GO:0032675)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0032971	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.0	GO:0046006	positive regulation of activated T cell proliferation(GO:0042104) regulation of activated T cell proliferation(GO:0046006)
0.0	0.1	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0021794	thalamus development(GO:0021794)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:1902339	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0032365	intracellular lipid transport(GO:0032365)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.0	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0046951	acetoacetic acid biosynthetic process(GO:0043441) ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.0	0.6	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.1	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.1	GO:0034227	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.0	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	2.3	GO:0016568	chromatin modification(GO:0016568)
0.0	0.0	GO:0022616	DNA strand elongation(GO:0022616)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0033363	secretory granule organization(GO:0033363)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.3	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.0	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.4	GO:0007602	phototransduction(GO:0007602)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.0	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.9	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	0.2	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.0	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.8	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.5	GO:0072395	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.0	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.0	GO:0030330	DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.1	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.0	0.0	GO:0042770	signal transduction in response to DNA damage(GO:0042770)
0.0	0.1	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.0	GO:0071941	nitrogen cycle metabolic process(GO:0071941)
0.0	0.1	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.8	GO:0051028	mRNA transport(GO:0051028)
0.0	0.0	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.1	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.5	GO:0006754	ATP biosynthetic process(GO:0006754)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.6	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	1.1	GO:0002102	podosome(GO:0002102)
0.1	0.4	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.8	GO:0000791	euchromatin(GO:0000791)
0.1	2.2	GO:0031519	PcG protein complex(GO:0031519)
0.1	0.3	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.4	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	0.8	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	0.4	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.3	GO:0000800	lateral element(GO:0000800)
0.1	0.4	GO:0042587	glycogen granule(GO:0042587)
0.1	0.5	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	0.7	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.1	0.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.3	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.4	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.1	0.2	GO:0005638	lamin filament(GO:0005638)
0.1	0.5	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.6	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.3	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	1.8	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.4	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.2	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.3	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	1.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.5	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.4	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0043230	extracellular organelle(GO:0043230)
0.0	0.5	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	1.3	GO:0016605	PML body(GO:0016605)
0.0	0.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0031904	endosome lumen(GO:0031904)
0.0	0.1	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.4	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	1.0	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.0	GO:0034399	nuclear periphery(GO:0034399)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.0	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.2	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
0.0	0.3	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.9	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.4	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	2.0	GO:0005769	early endosome(GO:0005769)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.0	GO:0005827	polar microtubule(GO:0005827)
0.0	0.6	GO:0030496	midbody(GO:0030496)
0.0	0.0	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.3	GO:0005657	replication fork(GO:0005657)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.4	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.2	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.3	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.3	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.0	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0030663	COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0	0.1	GO:0030914	STAGA complex(GO:0030914)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:0031985	Golgi cisterna(GO:0031985)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0042608	T cell receptor binding(GO:0042608)
0.2	1.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.2	1.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2	0.7	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2	0.6	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2	0.5	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.7	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.7	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.1	0.4	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	1.0	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.3	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.8	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.3	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.3	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.5	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.4	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	0.4	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.3	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1	0.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.3	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.2	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.3	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.2	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	1.1	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.3	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.2	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.3	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421)
0.1	0.5	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.7	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.5	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.1	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	0.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.2	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1	0.2	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.9	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.6	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	0.2	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.8	GO:0005035	death receptor activity(GO:0005035)
0.1	0.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.3	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.4	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.1	0.4	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.1	0.3	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1	0.2	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.5	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	0.2	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.6	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.2	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.2	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.2	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.8	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.5	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.3	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.3	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0046977	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.6	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.2	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.3	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.6	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.2	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	1.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	1.1	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.4	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.3	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.6	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.2	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.3	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.8	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.2	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.3	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.2	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	1.2	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.4	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.1	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.4	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.4	GO:0043621	protein self-association(GO:0043621)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.1	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.5	GO:0032182	ubiquitin-like protein binding(GO:0032182) ubiquitin binding(GO:0043130)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.0	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.3	GO:0045296	cadherin binding(GO:0045296)
0.0	0.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.3	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.5	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.3	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.5	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.6	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	1.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.9	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0072349	modified amino acid transmembrane transporter activity(GO:0072349)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.5	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	1.5	GO:0000287	magnesium ion binding(GO:0000287)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.3	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0015605	organophosphate ester transmembrane transporter activity(GO:0015605)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	2.3	GO:0003924	GTPase activity(GO:0003924)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	1.3	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.4	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.0	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.2	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.4	GO:0042393	histone binding(GO:0042393)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	4.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	1.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	0.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	2.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.1	4.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	1.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	1.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	1.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	0.6	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	0.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.1	3.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.7	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.6	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.6	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.5	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.7	PID ATM PATHWAY	ATM pathway
0.0	0.7	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.9	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.8	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.5	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.3	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.9	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.5	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.3	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.3	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.9	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	1.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	1.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	0.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	0.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	0.6	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	3.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.8	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	2.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.6	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	1.0	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.6	REACTOME MAP KINASE ACTIVATION IN TLR CASCADE	Genes involved in MAP kinase activation in TLR cascade
0.0	0.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.3	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.4	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.4	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.3	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.8	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.7	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins

Results for E2F6

Z-value: 1.43

Motif logo

Transcription factors associated with E2F6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the E2F6 motif across conditions

Conditions sorted by the z-value of the E2F6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: