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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for E2F8

Z-value: 2.23

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Transcription factors associated with E2F8

Gene Symbol	Gene ID	Gene Info
E2F8 Ensembl NCBI GeneCards UniProt	ENSG00000129173.8	E2F transcription factor 8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_19262896_19263111	E2F8	142	0.962109	0.80	8.9e-03	Click!
chr11_19261847_19262571	E2F8	289	0.911644	0.80	1.0e-02	Click!
chr11_19262741_19262892	E2F8	318	0.899104	0.73	2.6e-02	Click!
chr11_19266016_19266167	E2F8	2924	0.269982	-0.63	6.9e-02	Click!
chr11_19263245_19263885	E2F8	398	0.860911	0.52	1.5e-01	Click!

Activity of the E2F8 motif across conditions

Conditions sorted by the z-value of the E2F8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr8_6264376_6264527	1.07	RP11-115C21.2		212	0.59
chr9_98225729_98225880	0.88	PTCH1	patched 1	16963	0.18
chr12_4384320_4384557	0.81	CCND2-AS2	CCND2 antisense RNA 2	207	0.8
chr4_109087549_109087740	0.81	LEF1	lymphoid enhancer-binding factor 1	187	0.91
chr14_23398675_23398826	0.79	PRMT5	protein arginine methyltransferase 5	44	0.51
chr18_5237293_5237735	0.79	C18orf42	chromosome 18 open reading frame 42	40012	0.18
chr1_205561720_205561890	0.77	ENSG00000206762	.	2364	0.24
chr10_73846546_73846733	0.74	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	1447	0.48
chr8_134086774_134086935	0.74	SLA	Src-like-adaptor	14251	0.23
chr17_74267284_74267435	0.74	UBALD2	UBA-like domain containing 2	5575	0.13
chr10_116285471_116285868	0.72	ABLIM1	actin binding LIM protein 1	925	0.69
chr14_22972981_22973242	0.71	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	16940	0.09
chr17_73522364_73522644	0.69	LLGL2	lethal giant larvae homolog 2 (Drosophila)	634	0.56
chr6_135502778_135503522	0.68	MYB	v-myb avian myeloblastosis viral oncogene homolog	498	0.8
chr5_74347596_74347880	0.67	GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	21014	0.25
chr11_58945040_58945191	0.67	DTX4	deltex homolog 4 (Drosophila)	5150	0.18
chr14_91869630_91869781	0.67	CCDC88C	coiled-coil domain containing 88C	13985	0.23
chr11_66444702_66445046	0.66	RBM4B	RNA binding motif protein 4B	345	0.79
chr1_47696290_47696441	0.66	TAL1	T-cell acute lymphocytic leukemia 1	922	0.51
chr3_44753788_44754087	0.66	ZNF502	zinc finger protein 502	198	0.91
chr19_47125593_47125744	0.65	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	2626	0.14
chr5_156617150_156617301	0.64	ITK	IL2-inducible T-cell kinase	9388	0.13
chr4_76648928_76649551	0.64	G3BP2	GTPase activating protein (SH3 domain) binding protein 2	320	0.66
chr10_32667341_32667675	0.64	EPC1	enhancer of polycomb homolog 1 (Drosophila)	218	0.91
chr16_88532940_88533091	0.64	ENSG00000263456	.	2311	0.26
chr20_45979309_45979460	0.64	ZMYND8	zinc finger, MYND-type containing 8	1237	0.29
chr12_125477524_125477679	0.64	BRI3BP	BRI3 binding protein	645	0.71
chr7_128378913_128379302	0.64	CALU	calumenin	239	0.88
chr10_28622520_28622887	0.63	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	712	0.72
chr11_128382129_128382364	0.63	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	6957	0.25
chr3_183271619_183271774	0.63	KLHL6	kelch-like family member 6	1781	0.32
chr1_3663183_3663473	0.62	TP73-AS1	TP73 antisense RNA 1	12	0.96
chr16_71851540_71851781	0.62	AP1G1	adaptor-related protein complex 1, gamma 1 subunit	8556	0.13
chr7_72933755_72933914	0.62	BAZ1B	bromodomain adjacent to zinc finger domain, 1B	2768	0.21
chr6_10528716_10529334	0.62	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	436	0.83
chr13_52396863_52397161	0.62	RP11-327P2.5		18579	0.18
chr5_76103475_76103652	0.61	F2RL1	coagulation factor II (thrombin) receptor-like 1	11195	0.16
chr6_17705903_17706272	0.61	RP11-500C11.3		401	0.56
chr10_52086482_52086730	0.60	AC069547.1	HCG1745369; PRO3073; Uncharacterized protein	7692	0.21
chr1_89732840_89732991	0.60	GBP5	guanylate binding protein 5	3631	0.23
chr13_75899570_75899721	0.60	TBC1D4	TBC1 domain family, member 4	16022	0.24
chr6_24951710_24951975	0.60	FAM65B	family with sequence similarity 65, member B	15654	0.22
chrX_24664661_24664926	0.59	PCYT1B	phosphate cytidylyltransferase 1, choline, beta	482	0.78
chr5_71603712_71603915	0.59	ENSG00000244748	.	6702	0.2
chr14_90084669_90085459	0.59	FOXN3	forkhead box N3	410	0.78
chr10_121411714_121411984	0.58	BAG3	BCL2-associated athanogene 3	967	0.62
chr2_219259559_219259710	0.57	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	3427	0.11
chr15_60882704_60882968	0.57	RORA	RAR-related orphan receptor A	1904	0.39
chr14_22971510_22971661	0.57	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	15414	0.1
chr19_4909483_4909690	0.57	ARRDC5	arrestin domain containing 5	6707	0.13
chr8_57123539_57123769	0.57	PLAG1	pleiomorphic adenoma gene 1	184	0.83
chrX_78417700_78417909	0.56	GPR174	G protein-coupled receptor 174	8665	0.33
chr10_133796246_133796517	0.56	BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	946	0.66
chr2_96700541_96700692	0.56	GPAT2	glycerol-3-phosphate acyltransferase 2, mitochondrial	48	0.97
chr14_64854762_64854966	0.56	MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	94	0.97
chr2_96455429_96455580	0.56	AC008268.2		2464	0.4
chr22_40963716_40963867	0.56	MKL1	megakaryoblastic leukemia (translocation) 1	33976	0.14
chr15_38850039_38850247	0.56	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	2140	0.31
chr4_17579510_17580133	0.55	LAP3	leucine aminopeptidase 3	703	0.63
chr4_84377278_84378026	0.55	MRPS18C	mitochondrial ribosomal protein S18C	409	0.63
chr17_27894704_27894974	0.55	TP53I13	tumor protein p53 inducible protein 13	206	0.76
chr1_42385464_42385879	0.55	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	1293	0.61
chr5_110847374_110847606	0.54	STARD4-AS1	STARD4 antisense RNA 1	434	0.65
chr6_24935630_24936094	0.54	FAM65B	family with sequence similarity 65, member B	326	0.92
chr18_66381478_66381997	0.54	TMX3	thioredoxin-related transmembrane protein 3	557	0.55
chr8_29200137_29200318	0.54	DUSP4	dual specificity phosphatase 4	6095	0.17
chr17_29643674_29643825	0.53	CTD-2370N5.3		1909	0.22
chr6_149805654_149805958	0.53	ZC3H12D	zinc finger CCCH-type containing 12D	320	0.87
chr11_96073413_96073903	0.53	ENSG00000266192	.	944	0.55
chr10_115613974_115614183	0.53	DCLRE1A	DNA cross-link repair 1A	64	0.82
chr2_25391776_25391927	0.53	POMC	proopiomelanocortin	79	0.97
chr18_70644965_70645116	0.53	NETO1	neuropilin (NRP) and tolloid (TLL)-like 1	109856	0.07
chr19_4402510_4402661	0.53	CHAF1A	chromatin assembly factor 1, subunit A (p150)	74	0.93
chr6_5250510_5250661	0.53	LYRM4	LYR motif containing 4	10381	0.19
chr8_29953269_29953483	0.52	LEPROTL1	leptin receptor overlapping transcript-like 1	211	0.92
chr11_46353682_46353833	0.52	DGKZ	diacylglycerol kinase, zeta	698	0.63
chr17_18330712_18330863	0.52	KRT17P2	keratin 17 pseudogene 2	546	0.65
chr2_43038576_43038727	0.52	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	18919	0.23
chr12_48169092_48169458	0.52	SLC48A1	solute carrier family 48 (heme transporter), member 1	2284	0.21
chr21_26979075_26979478	0.51	MRPL39	mitochondrial ribosomal protein L39	520	0.77
chr10_8098395_8099007	0.51	GATA3	GATA binding protein 3	1932	0.5
chr17_30335047_30335869	0.51	LRRC37B	leucine rich repeat containing 37B	451	0.82
chr3_149419430_149419681	0.51	WWTR1	WW domain containing transcription regulator 1	1505	0.39
chr16_88714887_88715038	0.51	CYBA	cytochrome b-245, alpha polypeptide	1729	0.19
chr2_55241954_55242105	0.51	ENSG00000200086	.	372	0.88
chr5_156630678_156630829	0.51	CTB-4E7.1		20637	0.11
chr18_12947330_12947701	0.51	SEH1L	SEH1-like (S. cerevisiae)	383	0.86
chrX_152997744_152997895	0.50	ABCD1	ATP-binding cassette, sub-family D (ALD), member 1	2979	0.14
chr15_44119193_44119767	0.50	WDR76	WD repeat domain 76	294	0.8
chr18_67624277_67624428	0.50	CD226	CD226 molecule	60	0.99
chr12_1700698_1701264	0.50	FBXL14	F-box and leucine-rich repeat protein 14	2350	0.32
chr2_8627682_8628105	0.50	AC011747.7		188003	0.03
chr2_213880427_213880578	0.50	AC079610.1		5767	0.31
chr17_74268969_74269120	0.50	UBALD2	UBA-like domain containing 2	7260	0.13
chr7_73704780_73705014	0.50	CLIP2	CAP-GLY domain containing linker protein 2	1092	0.51
chr2_197030897_197031094	0.50	STK17B	serine/threonine kinase 17b	4729	0.22
chr1_100820231_100820573	0.50	CDC14A	cell division cycle 14A	1897	0.33
chr4_151953272_151953579	0.49	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing	16546	0.19
chr8_98806681_98806832	0.49	LAPTM4B	lysosomal protein transmembrane 4 beta	18679	0.16
chr13_52586601_52587118	0.49	ALG11	ALG11, alpha-1,2-mannosyltransferase	309	0.84
chr19_15574418_15574723	0.49	RASAL3	RAS protein activator like 3	812	0.5
chr1_27191814_27192102	0.49	SFN	stratifin	2325	0.17
chr12_32113291_32114105	0.49	KIAA1551	KIAA1551	1345	0.51
chr3_136153674_136153825	0.49	ENSG00000200571	.	4724	0.28
chr12_121628562_121628948	0.49	RP11-340F14.5		3396	0.22
chr10_43571610_43571906	0.49	RET	ret proto-oncogene	717	0.75
chr14_69864192_69864364	0.49	ERH	enhancer of rudimentary homolog (Drosophila)	738	0.55
chr17_43392092_43392277	0.49	ENSG00000199953	.	12679	0.13
chr6_25137772_25138250	0.49	ENSG00000222373	.	54630	0.11
chr2_231917286_231917557	0.49	RP11-223I10.1		666	0.63
chr3_192675469_192675839	0.48	MB21D2	Mab-21 domain containing 2	39704	0.21
chr11_107729049_107729490	0.48	SLC35F2	solute carrier family 35, member F2	18	0.98
chr17_58469595_58469783	0.48	USP32	ubiquitin specific peptidase 32	80	0.53
chr13_74807358_74807666	0.48	ENSG00000206617	.	55839	0.16
chr17_25784229_25784755	0.48	KSR1	kinase suppressor of ras 1	752	0.67
chr1_65429872_65430170	0.48	JAK1	Janus kinase 1	2166	0.38
chr21_43484008_43484190	0.48	UMODL1	uromodulin-like 1	1031	0.55
chr3_18466146_18466386	0.48	SATB1	SATB homeobox 1	34	0.98
chr16_30064127_30064361	0.48	FAM57B	family with sequence similarity 57, member B	0	0.66
chr19_36618567_36618742	0.47	TBCB	tubulin folding cofactor B	11680	0.09
chr17_73284974_73285211	0.47	SLC25A19	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19	201	0.88
chr1_184722984_184723419	0.47	EDEM3	ER degradation enhancer, mannosidase alpha-like 3	500	0.84
chr2_38974705_38974930	0.47	SRSF7	serine/arginine-rich splicing factor 7	1889	0.3
chr10_35416363_35416802	0.47	CREM	cAMP responsive element modulator	177	0.83
chr1_169863342_169863522	0.46	SCYL3	SCY1-like 3 (S. cerevisiae)	24	0.98
chr11_111472579_111472791	0.46	SIK2	salt-inducible kinase 2	430	0.82
chr12_125412025_125412330	0.46	UBC	ubiquitin C	10263	0.16
chr15_62353285_62353511	0.46	RP11-643M14.1		685	0.44
chr7_99235204_99236023	0.46	ZSCAN25	zinc finger and SCAN domain containing 25	18383	0.13
chr19_10425841_10426039	0.46	FDX1L	ferredoxin 1-like	745	0.4
chr8_128748233_128748473	0.46	MYC	v-myc avian myelocytomatosis viral oncogene homolog	23	0.99
chr12_131303058_131303233	0.46	ENSG00000238822	.	3247	0.24
chr10_103879598_103879834	0.46	LDB1	LIM domain binding 1	494	0.73
chr3_149419705_149419856	0.46	WWTR1	WW domain containing transcription regulator 1	1280	0.44
chr1_9353427_9353625	0.45	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	587	0.76
chr2_85108355_85108775	0.45	TRABD2A	TraB domain containing 2A	196	0.94
chr22_31685760_31685954	0.45	PIK3IP1	phosphoinositide-3-kinase interacting protein 1	2524	0.16
chr10_88853075_88853529	0.45	GLUD1	glutamate dehydrogenase 1	525	0.47
chr2_20250229_20250973	0.45	LAPTM4A	lysosomal protein transmembrane 4 alpha	1188	0.35
chr7_106505707_106506635	0.45	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	247	0.95
chr2_53995298_53995613	0.45	CHAC2	ChaC, cation transport regulator homolog 2 (E. coli)	526	0.73
chr13_24826594_24826745	0.45	SPATA13	spermatogenesis associated 13	813	0.56
chr19_44283632_44284486	0.45	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	1350	0.33
chr10_105302623_105302876	0.44	RP11-416N2.3		6083	0.14
chr21_37632629_37632945	0.44	ENSG00000238851	.	1958	0.3
chr2_129074489_129074760	0.44	HS6ST1	heparan sulfate 6-O-sulfotransferase 1	1527	0.48
chr17_43299697_43300109	0.44	CTD-2020K17.1		314	0.65
chr2_10261142_10261355	0.44	RRM2	ribonucleotide reductase M2	1207	0.36
chr14_75714424_75714717	0.44	RP11-293M10.2		11544	0.15
chr21_46340531_46340791	0.44	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	109	0.73
chr7_55955661_55956073	0.44	MRPS17	28S ribosomal protein S17, mitochondrial; HCG1984214, isoform CRA_a	897	0.5
chr4_153511797_153511976	0.44	ENSG00000268471	.	54306	0.12
chrX_20286137_20286347	0.44	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	719	0.77
chr6_25041553_25042305	0.44	RP3-425P12.5		138	0.72
chr2_38977802_38978009	0.44	SRSF7	serine/arginine-rich splicing factor 7	595	0.51
chr5_41870864_41871034	0.44	OXCT1	3-oxoacid CoA transferase 1	328	0.76
chr3_32470168_32470420	0.44	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	36763	0.17
chr3_10184279_10184522	0.44	VHL	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	928	0.36
chr20_39410185_39410336	0.43	ENSG00000238908	.	72609	0.12
chr2_208657414_208657565	0.43	FZD5	frizzled family receptor 5	23202	0.14
chr19_48706778_48706942	0.43	CTC-453G23.8		480	0.7
chr11_118964238_118964465	0.43	H2AFX	H2A histone family, member X	1826	0.14
chr10_63660110_63660434	0.43	ARID5B	AT rich interactive domain 5B (MRF1-like)	787	0.73
chr11_36476974_36477125	0.43	RP11-219O3.2		29377	0.16
chr4_4857702_4857853	0.43	MSX1	msh homeobox 1	3616	0.33
chr15_56535646_56535941	0.43	RFX7	regulatory factor X, 7	310	0.59
chr12_77124222_77124373	0.43	ZDHHC17	zinc finger, DHHC-type containing 17	33071	0.23
chr2_172016015_172016577	0.43	TLK1	tousled-like kinase 1	1047	0.6
chr19_51874762_51874926	0.43	NKG7	natural killer cell group 7 sequence	813	0.34
chr3_197476356_197476565	0.43	FYTTD1	forty-two-three domain containing 1	36	0.58
chr17_20420296_20420671	0.43	AC025627.9		309	0.87
chr10_70847421_70847679	0.43	SRGN	serglycin	324	0.89
chr13_98633423_98633574	0.42	IPO5	importin 5	1374	0.56
chr13_74805658_74805885	0.42	ENSG00000206617	.	57580	0.16
chr3_121964666_121964959	0.42	ENSG00000252170	.	199	0.94
chr1_41156793_41157159	0.42	NFYC	nuclear transcription factor Y, gamma	385	0.67
chr1_92948652_92949059	0.42	GFI1	growth factor independent 1 transcription repressor	656	0.79
chr8_57122958_57123494	0.42	PLAG1	pleiomorphic adenoma gene 1	612	0.59
chr20_30793940_30794091	0.42	PLAGL2	pleiomorphic adenoma gene-like 2	1579	0.27
chr1_150082423_150082787	0.42	PLEKHO1	pleckstrin homology domain containing, family O member 1	38768	0.11
chr17_7306837_7307441	0.42	TMEM256	transmembrane protein 256	219	0.49
chr15_86127194_86127729	0.42	RP11-815J21.2		4052	0.21
chr9_134273163_134273365	0.42	PRRC2B	proline-rich coiled-coil 2B	3784	0.26
chr1_66797787_66798583	0.42	PDE4B	phosphodiesterase 4B, cAMP-specific	313	0.94
chr12_124246037_124246461	0.42	DNAH10	dynein, axonemal, heavy chain 10	793	0.62
chr2_162094673_162094975	0.42	TANK	TRAF family member-associated NFKB activator	7127	0.21
chr1_198615390_198615565	0.42	PTPRC	protein tyrosine phosphatase, receptor type, C	7185	0.25
chr16_79321307_79321458	0.42	ENSG00000222244	.	23031	0.27
chr2_208395473_208395722	0.42	CREB1	cAMP responsive element binding protein 1	769	0.52
chr16_68055568_68055762	0.42	DUS2	dihydrouridine synthase 2	1194	0.25
chr11_33711519_33711731	0.41	RP4-541C22.5		6622	0.18
chr5_32814538_32814689	0.41	AC026703.1		25668	0.21
chr6_81164524_81164675	0.41	BCKDHB	branched chain keto acid dehydrogenase E1, beta polypeptide	348216	0.01
chr10_33500315_33500466	0.41	RP11-342D11.2		185	0.95
chr10_127860215_127860366	0.41	ENSG00000222740	.	26139	0.24
chr2_27631132_27631707	0.41	PPM1G	protein phosphatase, Mg2+/Mn2+ dependent, 1G	1030	0.33
chr16_67679075_67679512	0.41	RLTPR	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	143	0.91
chr5_150537577_150537728	0.41	ANXA6	annexin A6	209	0.95
chr10_82225521_82225672	0.41	TSPAN14	tetraspanin 14	6538	0.22
chr1_85741613_85741855	0.41	RP11-131L23.1		664	0.49

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.3	0.8	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.2	0.6	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.2	0.5	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.2	0.7	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2	0.5	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	0.4	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.4	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.5	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.4	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.5	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.1	0.2	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.5	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	0.5	GO:0006999	nuclear pore organization(GO:0006999)
0.1	0.3	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.7	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	1.1	GO:0060736	prostate gland growth(GO:0060736)
0.1	0.6	GO:0046950	cellular ketone body metabolic process(GO:0046950)
0.1	0.3	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	0.5	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.7	GO:0006547	histidine metabolic process(GO:0006547)
0.1	0.7	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.1	0.4	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.1	0.6	GO:0051383	kinetochore organization(GO:0051383)
0.1	0.3	GO:0090267	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	0.5	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.3	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.4	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.4	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.1	0.4	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.2	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.2	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.2	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.1	0.5	GO:0002860	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.2	GO:0032543	mitochondrial translation(GO:0032543)
0.1	0.2	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.5	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.4	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1	0.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.4	GO:0060023	soft palate development(GO:0060023)
0.1	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.1	0.3	GO:0022038	corpus callosum development(GO:0022038)
0.1	0.2	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.1	GO:0043369	alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
0.1	0.8	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.3	GO:0045056	transcytosis(GO:0045056)
0.1	0.5	GO:0046902	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.1	0.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.5	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.2	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.5	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	0.2	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.1	0.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.2	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1	0.3	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.1	0.2	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	0.2	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.2	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.1	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.1	0.5	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.7	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.1	0.2	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	1.0	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	0.4	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.1	GO:0046874	quinolinate metabolic process(GO:0046874)
0.1	0.1	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.1	0.3	GO:0050667	homocysteine metabolic process(GO:0050667)
0.1	0.3	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.1	0.2	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.1	GO:1905208	negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.1	0.5	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.3	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.2	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.1	0.2	GO:0019985	translesion synthesis(GO:0019985)
0.1	0.2	GO:0007549	dosage compensation(GO:0007549)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.5	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.3	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.1	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.3	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.1	0.2	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.4	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.2	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.5	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197) negative regulation of metanephros development(GO:0072217)
0.0	0.2	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.3	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.3	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.4	GO:0002467	germinal center formation(GO:0002467)
0.0	0.6	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.4	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.3	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.3	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.5	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.4	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.3	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.2	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.5	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.2	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.2	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.4	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.4	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.4	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.5	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166) adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.7	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.2	GO:0045217	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.3	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.2	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.4	GO:0033363	secretory granule organization(GO:0033363)
0.0	0.4	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.3	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	1.2	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.4	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.2	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.2	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.2	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:1903170	negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.5	GO:0006862	nucleotide transport(GO:0006862)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.3	GO:0006265	DNA topological change(GO:0006265)
0.0	0.4	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.1	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.3	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.3	GO:0001504	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.1	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.2	GO:0042069	regulation of catecholamine metabolic process(GO:0042069)
0.0	0.1	GO:0042424	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.0	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:2000134	negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0	0.2	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.0	0.4	GO:1903729	regulation of plasma membrane organization(GO:1903729)
0.0	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.4	GO:0006825	copper ion transport(GO:0006825)
0.0	0.2	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.4	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.3	GO:0007520	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.0	GO:0033240	positive regulation of cellular amine metabolic process(GO:0033240)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.0	0.6	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.2	GO:0019043	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0	0.0	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	1.2	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.2	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.9	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.2	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.5	GO:1900076	regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.3	GO:0010812	negative regulation of cell-substrate adhesion(GO:0010812)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.5	GO:2000117	negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0010458	exit from mitosis(GO:0010458)
0.0	0.3	GO:0051828	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.5	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.0	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.6	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.0	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.0	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	2.6	GO:0000375	RNA splicing, via transesterification reactions(GO:0000375)
0.0	0.0	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.3	GO:0034620	endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.0	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.1	GO:0022011	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0090278	negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.0	GO:0090189	regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	1.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.4	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.2	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.8	GO:0000077	DNA damage checkpoint(GO:0000077)
0.0	0.9	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.0	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.9	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.0	0.3	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.3	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.0	GO:0042754	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754) negative regulation of behavior(GO:0048521)
0.0	0.1	GO:1903311	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0	0.0	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.2	GO:0006400	tRNA modification(GO:0006400)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.8	GO:0097194	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.0	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.2	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.0	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	1.0	GO:0002576	platelet degranulation(GO:0002576)
0.0	0.6	GO:0042775	ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.5	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0	0.0	GO:0097035	regulation of membrane lipid distribution(GO:0097035)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	1.2	GO:0008380	RNA splicing(GO:0008380)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.0	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0051000	positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0	0.4	GO:0000084	mitotic S phase(GO:0000084)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.6	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.0	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.0	0.1	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.0	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.2	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	1.0	GO:0006415	translational termination(GO:0006415)
0.0	0.1	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.0	GO:0045932	negative regulation of muscle contraction(GO:0045932)
0.0	0.0	GO:0060745	mammary gland branching involved in pregnancy(GO:0060745)
0.0	0.0	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0	0.2	GO:0097193	intrinsic apoptotic signaling pathway(GO:0097193)
0.0	0.2	GO:0007140	male meiosis(GO:0007140)
0.0	0.0	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.0	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.2	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.2	GO:0034765	regulation of ion transmembrane transport(GO:0034765)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0043691	reverse cholesterol transport(GO:0043691)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0045727	positive regulation of translation(GO:0045727)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.3	GO:0001541	ovarian follicle development(GO:0001541)
0.0	0.0	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.0	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.3	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0042891	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.1	GO:0006563	L-serine metabolic process(GO:0006563)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.0	GO:0006301	postreplication repair(GO:0006301)
0.0	0.0	GO:0031365	N-terminal protein amino acid modification(GO:0031365)
0.0	0.0	GO:0001510	RNA methylation(GO:0001510)
0.0	0.0	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.3	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	0.1	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.4	GO:0006413	translational initiation(GO:0006413)
0.0	0.1	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.0	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.0	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.6	GO:0006826	iron ion transport(GO:0006826)
0.0	0.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.0	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.2	GO:0048524	positive regulation of viral process(GO:0048524) positive regulation of viral life cycle(GO:1903902)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.0	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.0	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.0	0.0	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.3	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.0	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.0	0.7	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.1	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.2	GO:0030593	neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.2	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0036503	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.0	GO:0010544	negative regulation of platelet activation(GO:0010544)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.2	0.6	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2	1.0	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	0.4	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.6	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	0.3	GO:0042629	mast cell granule(GO:0042629)
0.1	0.3	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	0.5	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.3	GO:0000124	SAGA complex(GO:0000124)
0.1	0.9	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.8	GO:0042555	MCM complex(GO:0042555)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.3	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	0.4	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.3	GO:0001740	Barr body(GO:0001740)
0.1	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.3	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	1.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.7	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	0.5	GO:0002102	podosome(GO:0002102)
0.1	0.4	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.3	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.4	GO:0005682	U5 snRNP(GO:0005682)
0.1	0.3	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.1	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.4	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	0.2	GO:0030891	VCB complex(GO:0030891)
0.1	0.3	GO:0000125	PCAF complex(GO:0000125)
0.1	0.9	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.4	GO:0005683	U7 snRNP(GO:0005683)
0.1	0.2	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	0.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.3	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.5	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0043230	extracellular organelle(GO:0043230)
0.0	0.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	1.5	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.3	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.4	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	2.5	GO:0034399	nuclear periphery(GO:0034399)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.3	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.4	GO:0032039	integrator complex(GO:0032039)
0.0	0.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.4	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.3	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	1.3	GO:0015030	Cajal body(GO:0015030)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	1.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.9	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	1.7	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0090568	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.2	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	1.6	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0031312	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of organelle membrane(GO:0031312) extrinsic component of endosome membrane(GO:0031313)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.8	GO:0016592	mediator complex(GO:0016592)
0.0	0.2	GO:0071565	nBAF complex(GO:0071565)
0.0	0.3	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.0	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.0	0.3	GO:0071203	WASH complex(GO:0071203)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.5	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.8	GO:0016605	PML body(GO:0016605)
0.0	0.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	1.0	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.0	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.5	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	1.3	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.5	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.6	GO:0030118	clathrin coat(GO:0030118)
0.0	0.1	GO:0000792	heterochromatin(GO:0000792)
0.0	0.8	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.5	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.5	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	1.4	GO:0031968	organelle outer membrane(GO:0031968)
0.0	0.0	GO:0001741	XY body(GO:0001741)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	1.3	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.0	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.9	GO:0000785	chromatin(GO:0000785)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.2	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.5	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.2	GO:0044452	nucleolar part(GO:0044452)
0.0	0.1	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.2	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.7	GO:0000502	proteasome complex(GO:0000502)
0.0	0.6	GO:0016604	nuclear body(GO:0016604)
0.0	0.0	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	2.3	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0005871	kinesin complex(GO:0005871)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.0	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.0	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.3	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	8.1	GO:0005730	nucleolus(GO:0005730)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.3	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.2	0.6	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.2	0.6	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.2	0.6	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.2	0.5	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.4	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.8	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.5	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.4	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.6	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.4	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.1	0.4	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.3	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.4	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.1	0.7	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.3	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.2	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.1	0.3	GO:0016531	copper chaperone activity(GO:0016531)
0.1	0.3	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	0.5	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.1	0.2	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1	0.4	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.3	GO:0051920	peroxiredoxin activity(GO:0051920)
0.1	0.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.1	0.4	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.2	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.3	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.5	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.1	0.1	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.2	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1	0.3	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.9	GO:0070888	E-box binding(GO:0070888)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.4	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	0.6	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	0.2	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.6	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.2	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.5	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.2	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	1.1	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.4	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.4	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	1.3	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.4	GO:0017166	vinculin binding(GO:0017166)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.5	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.2	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.4	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	1.3	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0	0.5	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.5	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.4	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	1.3	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.3	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	1.1	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.5	GO:0043621	protein self-association(GO:0043621)
0.0	0.2	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.4	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	1.5	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.2	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.6	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.3	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.5	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.6	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.2	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.4	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	3.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.5	GO:0051536	iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.4	GO:0005343	organic acid:sodium symporter activity(GO:0005343)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.3	GO:0043022	ribosome binding(GO:0043022)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.2	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.7	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0	0.3	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.0	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.6	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.3	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.9	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	1.3	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	1.3	GO:0003690	double-stranded DNA binding(GO:0003690)
0.0	0.3	GO:1990837	sequence-specific double-stranded DNA binding(GO:1990837)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.4	GO:0051087	chaperone binding(GO:0051087)
0.0	0.1	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.3	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	1.0	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	1.4	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.1	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.3	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.9	GO:0008168	methyltransferase activity(GO:0008168)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.3	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.2	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.4	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.3	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.4	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.0	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.0	GO:0004111	creatine kinase activity(GO:0004111)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	4.4	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	1.6	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	2.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.6	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.5	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.5	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.7	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.3	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.3	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.5	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.4	PID BMP PATHWAY	BMP receptor signaling
0.0	0.3	PID ATM PATHWAY	ATM pathway
0.0	0.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.3	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	0.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.1	REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS	Genes involved in Metabolism of lipids and lipoproteins
0.1	0.6	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	0.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.6	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	2.1	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	1.7	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.1	1.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.8	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.7	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	1.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.3	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.1	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.9	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.6	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	2.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.3	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.6	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.2	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	1.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.9	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	2.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.6	REACTOME HIV LIFE CYCLE	Genes involved in HIV Life Cycle
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.7	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.0	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.0	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.1	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.0	REACTOME REGULATION OF MITOTIC CELL CYCLE	Genes involved in Regulation of mitotic cell cycle
0.0	0.1	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events

Results for E2F8

Z-value: 2.23

Motif logo

Transcription factors associated with E2F8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the E2F8 motif across conditions

Conditions sorted by the z-value of the E2F8 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: