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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for E2F8

Z-value: 2.23

Motif logo

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Transcription factors associated with E2F8

Gene Symbol Gene ID Gene Info
ENSG00000129173.8 E2F8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
E2F8chr11_19262896_192631111420.9621090.808.9e-03Click!
E2F8chr11_19261847_192625712890.9116440.801.0e-02Click!
E2F8chr11_19262741_192628923180.8991040.732.6e-02Click!
E2F8chr11_19266016_1926616729240.269982-0.636.9e-02Click!
E2F8chr11_19263245_192638853980.8609110.521.5e-01Click!

Activity of the E2F8 motif across conditions

Conditions sorted by the z-value of the E2F8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_6264376_6264527 1.07 RP11-115C21.2

212
0.59
chr9_98225729_98225880 0.88 PTCH1
patched 1
16963
0.18
chr12_4384320_4384557 0.81 CCND2-AS2
CCND2 antisense RNA 2
207
0.8
chr4_109087549_109087740 0.81 LEF1
lymphoid enhancer-binding factor 1
187
0.91
chr14_23398675_23398826 0.79 PRMT5
protein arginine methyltransferase 5
44
0.51
chr18_5237293_5237735 0.79 C18orf42
chromosome 18 open reading frame 42
40012
0.18
chr1_205561720_205561890 0.77 ENSG00000206762
.
2364
0.24
chr10_73846546_73846733 0.74 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
1447
0.48
chr8_134086774_134086935 0.74 SLA
Src-like-adaptor
14251
0.23
chr17_74267284_74267435 0.74 UBALD2
UBA-like domain containing 2
5575
0.13
chr10_116285471_116285868 0.72 ABLIM1
actin binding LIM protein 1
925
0.69
chr14_22972981_22973242 0.71 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
16940
0.09
chr17_73522364_73522644 0.69 LLGL2
lethal giant larvae homolog 2 (Drosophila)
634
0.56
chr6_135502778_135503522 0.68 MYB
v-myb avian myeloblastosis viral oncogene homolog
498
0.8
chr5_74347596_74347880 0.67 GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
21014
0.25
chr11_58945040_58945191 0.67 DTX4
deltex homolog 4 (Drosophila)
5150
0.18
chr14_91869630_91869781 0.67 CCDC88C
coiled-coil domain containing 88C
13985
0.23
chr11_66444702_66445046 0.66 RBM4B
RNA binding motif protein 4B
345
0.79
chr1_47696290_47696441 0.66 TAL1
T-cell acute lymphocytic leukemia 1
922
0.51
chr3_44753788_44754087 0.66 ZNF502
zinc finger protein 502
198
0.91
chr19_47125593_47125744 0.65 PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
2626
0.14
chr5_156617150_156617301 0.64 ITK
IL2-inducible T-cell kinase
9388
0.13
chr4_76648928_76649551 0.64 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
320
0.66
chr10_32667341_32667675 0.64 EPC1
enhancer of polycomb homolog 1 (Drosophila)
218
0.91
chr16_88532940_88533091 0.64 ENSG00000263456
.
2311
0.26
chr20_45979309_45979460 0.64 ZMYND8
zinc finger, MYND-type containing 8
1237
0.29
chr12_125477524_125477679 0.64 BRI3BP
BRI3 binding protein
645
0.71
chr7_128378913_128379302 0.64 CALU
calumenin
239
0.88
chr10_28622520_28622887 0.63 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
712
0.72
chr11_128382129_128382364 0.63 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
6957
0.25
chr3_183271619_183271774 0.63 KLHL6
kelch-like family member 6
1781
0.32
chr1_3663183_3663473 0.62 TP73-AS1
TP73 antisense RNA 1
12
0.96
chr16_71851540_71851781 0.62 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
8556
0.13
chr7_72933755_72933914 0.62 BAZ1B
bromodomain adjacent to zinc finger domain, 1B
2768
0.21
chr6_10528716_10529334 0.62 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
436
0.83
chr13_52396863_52397161 0.62 RP11-327P2.5

18579
0.18
chr5_76103475_76103652 0.61 F2RL1
coagulation factor II (thrombin) receptor-like 1
11195
0.16
chr6_17705903_17706272 0.61 RP11-500C11.3

401
0.56
chr10_52086482_52086730 0.60 AC069547.1
HCG1745369; PRO3073; Uncharacterized protein
7692
0.21
chr1_89732840_89732991 0.60 GBP5
guanylate binding protein 5
3631
0.23
chr13_75899570_75899721 0.60 TBC1D4
TBC1 domain family, member 4
16022
0.24
chr6_24951710_24951975 0.60 FAM65B
family with sequence similarity 65, member B
15654
0.22
chrX_24664661_24664926 0.59 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
482
0.78
chr5_71603712_71603915 0.59 ENSG00000244748
.
6702
0.2
chr14_90084669_90085459 0.59 FOXN3
forkhead box N3
410
0.78
chr10_121411714_121411984 0.58 BAG3
BCL2-associated athanogene 3
967
0.62
chr2_219259559_219259710 0.57 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
3427
0.11
chr15_60882704_60882968 0.57 RORA
RAR-related orphan receptor A
1904
0.39
chr14_22971510_22971661 0.57 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
15414
0.1
chr19_4909483_4909690 0.57 ARRDC5
arrestin domain containing 5
6707
0.13
chr8_57123539_57123769 0.57 PLAG1
pleiomorphic adenoma gene 1
184
0.83
chrX_78417700_78417909 0.56 GPR174
G protein-coupled receptor 174
8665
0.33
chr10_133796246_133796517 0.56 BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
946
0.66
chr2_96700541_96700692 0.56 GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
48
0.97
chr14_64854762_64854966 0.56 MTHFD1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
94
0.97
chr2_96455429_96455580 0.56 AC008268.2

2464
0.4
chr22_40963716_40963867 0.56 MKL1
megakaryoblastic leukemia (translocation) 1
33976
0.14
chr15_38850039_38850247 0.56 RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
2140
0.31
chr4_17579510_17580133 0.55 LAP3
leucine aminopeptidase 3
703
0.63
chr4_84377278_84378026 0.55 MRPS18C
mitochondrial ribosomal protein S18C
409
0.63
chr17_27894704_27894974 0.55 TP53I13
tumor protein p53 inducible protein 13
206
0.76
chr1_42385464_42385879 0.55 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
1293
0.61
chr5_110847374_110847606 0.54 STARD4-AS1
STARD4 antisense RNA 1
434
0.65
chr6_24935630_24936094 0.54 FAM65B
family with sequence similarity 65, member B
326
0.92
chr18_66381478_66381997 0.54 TMX3
thioredoxin-related transmembrane protein 3
557
0.55
chr8_29200137_29200318 0.54 DUSP4
dual specificity phosphatase 4
6095
0.17
chr17_29643674_29643825 0.53 CTD-2370N5.3

1909
0.22
chr6_149805654_149805958 0.53 ZC3H12D
zinc finger CCCH-type containing 12D
320
0.87
chr11_96073413_96073903 0.53 ENSG00000266192
.
944
0.55
chr10_115613974_115614183 0.53 DCLRE1A
DNA cross-link repair 1A
64
0.82
chr2_25391776_25391927 0.53 POMC
proopiomelanocortin
79
0.97
chr18_70644965_70645116 0.53 NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
109856
0.07
chr19_4402510_4402661 0.53 CHAF1A
chromatin assembly factor 1, subunit A (p150)
74
0.93
chr6_5250510_5250661 0.53 LYRM4
LYR motif containing 4
10381
0.19
chr8_29953269_29953483 0.52 LEPROTL1
leptin receptor overlapping transcript-like 1
211
0.92
chr11_46353682_46353833 0.52 DGKZ
diacylglycerol kinase, zeta
698
0.63
chr17_18330712_18330863 0.52 KRT17P2
keratin 17 pseudogene 2
546
0.65
chr2_43038576_43038727 0.52 HAAO
3-hydroxyanthranilate 3,4-dioxygenase
18919
0.23
chr12_48169092_48169458 0.52 SLC48A1
solute carrier family 48 (heme transporter), member 1
2284
0.21
chr21_26979075_26979478 0.51 MRPL39
mitochondrial ribosomal protein L39
520
0.77
chr10_8098395_8099007 0.51 GATA3
GATA binding protein 3
1932
0.5
chr17_30335047_30335869 0.51 LRRC37B
leucine rich repeat containing 37B
451
0.82
chr3_149419430_149419681 0.51 WWTR1
WW domain containing transcription regulator 1
1505
0.39
chr16_88714887_88715038 0.51 CYBA
cytochrome b-245, alpha polypeptide
1729
0.19
chr2_55241954_55242105 0.51 ENSG00000200086
.
372
0.88
chr5_156630678_156630829 0.51 CTB-4E7.1

20637
0.11
chr18_12947330_12947701 0.51 SEH1L
SEH1-like (S. cerevisiae)
383
0.86
chrX_152997744_152997895 0.50 ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
2979
0.14
chr15_44119193_44119767 0.50 WDR76
WD repeat domain 76
294
0.8
chr18_67624277_67624428 0.50 CD226
CD226 molecule
60
0.99
chr12_1700698_1701264 0.50 FBXL14
F-box and leucine-rich repeat protein 14
2350
0.32
chr2_8627682_8628105 0.50 AC011747.7

188003
0.03
chr2_213880427_213880578 0.50 AC079610.1

5767
0.31
chr17_74268969_74269120 0.50 UBALD2
UBA-like domain containing 2
7260
0.13
chr7_73704780_73705014 0.50 CLIP2
CAP-GLY domain containing linker protein 2
1092
0.51
chr2_197030897_197031094 0.50 STK17B
serine/threonine kinase 17b
4729
0.22
chr1_100820231_100820573 0.50 CDC14A
cell division cycle 14A
1897
0.33
chr4_151953272_151953579 0.49 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
16546
0.19
chr8_98806681_98806832 0.49 LAPTM4B
lysosomal protein transmembrane 4 beta
18679
0.16
chr13_52586601_52587118 0.49 ALG11
ALG11, alpha-1,2-mannosyltransferase
309
0.84
chr19_15574418_15574723 0.49 RASAL3
RAS protein activator like 3
812
0.5
chr1_27191814_27192102 0.49 SFN
stratifin
2325
0.17
chr12_32113291_32114105 0.49 KIAA1551
KIAA1551
1345
0.51
chr3_136153674_136153825 0.49 ENSG00000200571
.
4724
0.28
chr12_121628562_121628948 0.49 RP11-340F14.5

3396
0.22
chr10_43571610_43571906 0.49 RET
ret proto-oncogene
717
0.75
chr14_69864192_69864364 0.49 ERH
enhancer of rudimentary homolog (Drosophila)
738
0.55
chr17_43392092_43392277 0.49 ENSG00000199953
.
12679
0.13
chr6_25137772_25138250 0.49 ENSG00000222373
.
54630
0.11
chr2_231917286_231917557 0.49 RP11-223I10.1

666
0.63
chr3_192675469_192675839 0.48 MB21D2
Mab-21 domain containing 2
39704
0.21
chr11_107729049_107729490 0.48 SLC35F2
solute carrier family 35, member F2
18
0.98
chr17_58469595_58469783 0.48 USP32
ubiquitin specific peptidase 32
80
0.53
chr13_74807358_74807666 0.48 ENSG00000206617
.
55839
0.16
chr17_25784229_25784755 0.48 KSR1
kinase suppressor of ras 1
752
0.67
chr1_65429872_65430170 0.48 JAK1
Janus kinase 1
2166
0.38
chr21_43484008_43484190 0.48 UMODL1
uromodulin-like 1
1031
0.55
chr3_18466146_18466386 0.48 SATB1
SATB homeobox 1
34
0.98
chr16_30064127_30064361 0.48 FAM57B
family with sequence similarity 57, member B
0
0.66
chr19_36618567_36618742 0.47 TBCB
tubulin folding cofactor B
11680
0.09
chr17_73284974_73285211 0.47 SLC25A19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
201
0.88
chr1_184722984_184723419 0.47 EDEM3
ER degradation enhancer, mannosidase alpha-like 3
500
0.84
chr2_38974705_38974930 0.47 SRSF7
serine/arginine-rich splicing factor 7
1889
0.3
chr10_35416363_35416802 0.47 CREM
cAMP responsive element modulator
177
0.83
chr1_169863342_169863522 0.46 SCYL3
SCY1-like 3 (S. cerevisiae)
24
0.98
chr11_111472579_111472791 0.46 SIK2
salt-inducible kinase 2
430
0.82
chr12_125412025_125412330 0.46 UBC
ubiquitin C
10263
0.16
chr15_62353285_62353511 0.46 RP11-643M14.1

685
0.44
chr7_99235204_99236023 0.46 ZSCAN25
zinc finger and SCAN domain containing 25
18383
0.13
chr19_10425841_10426039 0.46 FDX1L
ferredoxin 1-like
745
0.4
chr8_128748233_128748473 0.46 MYC
v-myc avian myelocytomatosis viral oncogene homolog
23
0.99
chr12_131303058_131303233 0.46 ENSG00000238822
.
3247
0.24
chr10_103879598_103879834 0.46 LDB1
LIM domain binding 1
494
0.73
chr3_149419705_149419856 0.46 WWTR1
WW domain containing transcription regulator 1
1280
0.44
chr1_9353427_9353625 0.45 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
587
0.76
chr2_85108355_85108775 0.45 TRABD2A
TraB domain containing 2A
196
0.94
chr22_31685760_31685954 0.45 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
2524
0.16
chr10_88853075_88853529 0.45 GLUD1
glutamate dehydrogenase 1
525
0.47
chr2_20250229_20250973 0.45 LAPTM4A
lysosomal protein transmembrane 4 alpha
1188
0.35
chr7_106505707_106506635 0.45 PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
247
0.95
chr2_53995298_53995613 0.45 CHAC2
ChaC, cation transport regulator homolog 2 (E. coli)
526
0.73
chr13_24826594_24826745 0.45 SPATA13
spermatogenesis associated 13
813
0.56
chr19_44283632_44284486 0.45 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
1350
0.33
chr10_105302623_105302876 0.44 RP11-416N2.3

6083
0.14
chr21_37632629_37632945 0.44 ENSG00000238851
.
1958
0.3
chr2_129074489_129074760 0.44 HS6ST1
heparan sulfate 6-O-sulfotransferase 1
1527
0.48
chr17_43299697_43300109 0.44 CTD-2020K17.1

314
0.65
chr2_10261142_10261355 0.44 RRM2
ribonucleotide reductase M2
1207
0.36
chr14_75714424_75714717 0.44 RP11-293M10.2

11544
0.15
chr21_46340531_46340791 0.44 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
109
0.73
chr7_55955661_55956073 0.44 MRPS17
28S ribosomal protein S17, mitochondrial; HCG1984214, isoform CRA_a
897
0.5
chr4_153511797_153511976 0.44 ENSG00000268471
.
54306
0.12
chrX_20286137_20286347 0.44 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
719
0.77
chr6_25041553_25042305 0.44 RP3-425P12.5

138
0.72
chr2_38977802_38978009 0.44 SRSF7
serine/arginine-rich splicing factor 7
595
0.51
chr5_41870864_41871034 0.44 OXCT1
3-oxoacid CoA transferase 1
328
0.76
chr3_32470168_32470420 0.44 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
36763
0.17
chr3_10184279_10184522 0.44 VHL
von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
928
0.36
chr20_39410185_39410336 0.43 ENSG00000238908
.
72609
0.12
chr2_208657414_208657565 0.43 FZD5
frizzled family receptor 5
23202
0.14
chr19_48706778_48706942 0.43 CTC-453G23.8

480
0.7
chr11_118964238_118964465 0.43 H2AFX
H2A histone family, member X
1826
0.14
chr10_63660110_63660434 0.43 ARID5B
AT rich interactive domain 5B (MRF1-like)
787
0.73
chr11_36476974_36477125 0.43 RP11-219O3.2

29377
0.16
chr4_4857702_4857853 0.43 MSX1
msh homeobox 1
3616
0.33
chr15_56535646_56535941 0.43 RFX7
regulatory factor X, 7
310
0.59
chr12_77124222_77124373 0.43 ZDHHC17
zinc finger, DHHC-type containing 17
33071
0.23
chr2_172016015_172016577 0.43 TLK1
tousled-like kinase 1
1047
0.6
chr19_51874762_51874926 0.43 NKG7
natural killer cell group 7 sequence
813
0.34
chr3_197476356_197476565 0.43 FYTTD1
forty-two-three domain containing 1
36
0.58
chr17_20420296_20420671 0.43 AC025627.9

309
0.87
chr10_70847421_70847679 0.43 SRGN
serglycin
324
0.89
chr13_98633423_98633574 0.42 IPO5
importin 5
1374
0.56
chr13_74805658_74805885 0.42 ENSG00000206617
.
57580
0.16
chr3_121964666_121964959 0.42 ENSG00000252170
.
199
0.94
chr1_41156793_41157159 0.42 NFYC
nuclear transcription factor Y, gamma
385
0.67
chr1_92948652_92949059 0.42 GFI1
growth factor independent 1 transcription repressor
656
0.79
chr8_57122958_57123494 0.42 PLAG1
pleiomorphic adenoma gene 1
612
0.59
chr20_30793940_30794091 0.42 PLAGL2
pleiomorphic adenoma gene-like 2
1579
0.27
chr1_150082423_150082787 0.42 PLEKHO1
pleckstrin homology domain containing, family O member 1
38768
0.11
chr17_7306837_7307441 0.42 TMEM256
transmembrane protein 256
219
0.49
chr15_86127194_86127729 0.42 RP11-815J21.2

4052
0.21
chr9_134273163_134273365 0.42 PRRC2B
proline-rich coiled-coil 2B
3784
0.26
chr1_66797787_66798583 0.42 PDE4B
phosphodiesterase 4B, cAMP-specific
313
0.94
chr12_124246037_124246461 0.42 DNAH10
dynein, axonemal, heavy chain 10
793
0.62
chr2_162094673_162094975 0.42 TANK
TRAF family member-associated NFKB activator
7127
0.21
chr1_198615390_198615565 0.42 PTPRC
protein tyrosine phosphatase, receptor type, C
7185
0.25
chr16_79321307_79321458 0.42 ENSG00000222244
.
23031
0.27
chr2_208395473_208395722 0.42 CREB1
cAMP responsive element binding protein 1
769
0.52
chr16_68055568_68055762 0.42 DUS2
dihydrouridine synthase 2
1194
0.25
chr11_33711519_33711731 0.41 RP4-541C22.5

6622
0.18
chr5_32814538_32814689 0.41 AC026703.1

25668
0.21
chr6_81164524_81164675 0.41 BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide
348216
0.01
chr10_33500315_33500466 0.41 RP11-342D11.2

185
0.95
chr10_127860215_127860366 0.41 ENSG00000222740
.
26139
0.24
chr2_27631132_27631707 0.41 PPM1G
protein phosphatase, Mg2+/Mn2+ dependent, 1G
1030
0.33
chr16_67679075_67679512 0.41 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
143
0.91
chr5_150537577_150537728 0.41 ANXA6
annexin A6
209
0.95
chr10_82225521_82225672 0.41 TSPAN14
tetraspanin 14
6538
0.22
chr1_85741613_85741855 0.41 RP11-131L23.1

664
0.49

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of E2F8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.3 0.8 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 0.5 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.2 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.4 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.4 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.4 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.2 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.5 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.1 GO:0060736 prostate gland growth(GO:0060736)
0.1 0.6 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.3 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.7 GO:0006547 histidine metabolic process(GO:0006547)
0.1 0.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.4 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 0.6 GO:0051383 kinetochore organization(GO:0051383)
0.1 0.3 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.5 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.1 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.2 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.1 0.5 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.2 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 0.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.4 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1 0.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.2 GO:0007100 mitotic centrosome separation(GO:0007100)
0.1 0.1 GO:0043369 alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
0.1 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.5 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.1 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.1 0.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.2 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.2 GO:0001821 histamine secretion(GO:0001821)
0.1 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.1 0.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.2 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 1.0 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.1 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.1 0.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.3 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.1 0.2 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.1 GO:1905208 negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.1 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.2 GO:0007549 dosage compensation(GO:0007549)
0.1 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.3 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.1 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.3 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.1 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.4 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.1 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197) negative regulation of metanephros development(GO:0072217)
0.0 0.2 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.3 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.3 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.4 GO:0002467 germinal center formation(GO:0002467)
0.0 0.6 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0032048 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.2 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.0 GO:0006166 purine ribonucleoside salvage(GO:0006166) adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.7 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0045217 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.0 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.2 GO:0061515 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.4 GO:0033363 secretory granule organization(GO:0033363)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 1.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.2 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.2 GO:0097191 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:1903170 negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.5 GO:0006862 nucleotide transport(GO:0006862)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.3 GO:0001504 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.1 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.2 GO:0042069 regulation of catecholamine metabolic process(GO:0042069)
0.0 0.1 GO:0042424 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.4 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0002837 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0 0.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.0 GO:0033240 positive regulation of cellular amine metabolic process(GO:0033240)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.6 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.2 GO:0019043 establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0 0.0 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 1.2 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.9 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.5 GO:1900076 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.3 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.5 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0010458 exit from mitosis(GO:0010458)
0.0 0.3 GO:0051828 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.5 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.0 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.6 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 2.6 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.0 0.0 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.3 GO:0034620 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0022011 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.0 GO:0090189 regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 1.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.4 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.2 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.8 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.9 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.0 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.9 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.3 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:0042754 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754) negative regulation of behavior(GO:0048521)
0.0 0.1 GO:1903311 regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.2 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.8 GO:0097194 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.0 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 1.0 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.6 GO:0042775 ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.5 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.0 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0 0.0 GO:0097035 regulation of membrane lipid distribution(GO:0097035)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.2 GO:0008380 RNA splicing(GO:0008380)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.0 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0051000 positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0 0.4 GO:0000084 mitotic S phase(GO:0000084)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.0 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.6 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.0 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.1 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 1.0 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0045932 negative regulation of muscle contraction(GO:0045932)
0.0 0.0 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0 0.2 GO:0097193 intrinsic apoptotic signaling pathway(GO:0097193)
0.0 0.2 GO:0007140 male meiosis(GO:0007140)
0.0 0.0 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.0 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.2 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.2 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.0 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0071445 obsolete cellular response to protein stimulus(GO:0071445)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0043691 reverse cholesterol transport(GO:0043691)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0042891 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.1 GO:0006563 L-serine metabolic process(GO:0006563)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.0 GO:0006301 postreplication repair(GO:0006301)
0.0 0.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.0 GO:0001510 RNA methylation(GO:0001510)
0.0 0.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.3 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.1 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.4 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.6 GO:0006826 iron ion transport(GO:0006826)
0.0 0.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.0 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.2 GO:0048524 positive regulation of viral process(GO:0048524) positive regulation of viral life cycle(GO:1903902)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.0 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.0 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.7 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.2 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0036503 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0 0.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.0 GO:0010544 negative regulation of platelet activation(GO:0010544)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.2 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 1.0 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.3 GO:0042629 mast cell granule(GO:0042629)
0.1 0.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0000124 SAGA complex(GO:0000124)
0.1 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.3 GO:0001740 Barr body(GO:0001740)
0.1 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.5 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.3 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.1 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.2 GO:0030891 VCB complex(GO:0030891)
0.1 0.3 GO:0000125 PCAF complex(GO:0000125)
0.1 0.9 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.2 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.5 GO:0008278 cohesin complex(GO:0008278)
0.0 0.0 GO:0043230 extracellular organelle(GO:0043230)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.3 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 2.5 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 1.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.9 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0031312 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of organelle membrane(GO:0031312) extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 1.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 1.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.5 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.6 GO:0030118 clathrin coat(GO:0030118)
0.0 0.1 GO:0000792 heterochromatin(GO:0000792)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.4 GO:0031968 organelle outer membrane(GO:0031968)
0.0 0.0 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.0 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.9 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0044452 nucleolar part(GO:0044452)
0.0 0.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.7 GO:0000502 proteasome complex(GO:0000502)
0.0 0.6 GO:0016604 nuclear body(GO:0016604)
0.0 0.0 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 2.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.3 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 8.1 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.6 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.2 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.8 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.3 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.5 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.9 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.3 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 1.3 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.5 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 1.5 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 3.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.2 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.7 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.0 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.9 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 1.3 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.3 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0032405 MutLalpha complex binding(GO:0032405)
0.0 0.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 1.4 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0 0.9 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.4 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.4 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.1 REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS Genes involved in Metabolism of lipids and lipoproteins
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.1 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.6 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 2.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME HIV LIFE CYCLE Genes involved in HIV Life Cycle
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.0 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.0 REACTOME REGULATION OF MITOTIC CELL CYCLE Genes involved in Regulation of mitotic cell cycle
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events