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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EBF1

Z-value: 1.09

Motif logo

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Transcription factors associated with EBF1

Gene Symbol Gene ID Gene Info
EBF1
ENSG00000164330.12 EBF1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
EBF1chr5_158532158_15853230954640.273373-0.808.9e-03Click!
EBF1chr5_158518406_15851855782200.259216-0.599.4e-02Click!
EBF1chr5_158479447_158479665471450.1462920.462.1e-01Click!
EBF1chr5_158533512_15853397169720.2612670.462.1e-01Click!
EBF1chr5_158478044_158478213485730.1422030.393.0e-01Click!

Activity of the EBF1 motif across conditions

Conditions sorted by the z-value of the EBF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_114136713_114136864 0.23 ACSL5
 acyl-CoA synthetase long-chain family member 5
 831
 0.63
chr17_61784423_61784574 0.23 STRADA
 STE20-related kinase adaptor alpha
 2683
 0.21
chr6_166954866_166955076 0.20 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
 967
 0.56
chr2_97439727_97440064 0.20 CNNM4
 cyclin M4
 13256
 0.14
chr11_18728014_18728472 0.19 RP11-1081L13.4
159
 0.94
chr1_26644827_26645344 0.19 UBXN11
 UBX domain protein 11
 231
 0.76
chr4_7972052_7972961 0.18 AFAP1
 actin filament associated protein 1
 30853
 0.14
chr19_18112722_18113118 0.18 ARRDC2
 arrestin domain containing 2
 979
 0.48
chr15_89437756_89438448 0.18 HAPLN3
 hyaluronan and proteoglycan link protein 3
 662
 0.7
chr5_1105065_1105874 0.18 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
 6681
 0.19
chr9_137417944_137418506 0.17 COL5A1
 collagen, type V, alpha 1
 115395
 0.05
chr19_10628197_10628587 0.17 S1PR5
 sphingosine-1-phosphate receptor 5
 215
 0.87
chr14_22957632_22957783 0.17 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 1536
 0.24
chr9_139776272_139777152 0.17 TRAF2
 TNF receptor-associated factor 2
 327
 0.72
chrX_130912849_130913434 0.16 ENSG00000200587
 .
 159843
 0.04
chr2_10375130_10375281 0.16 ENSG00000265418
 .
 42408
 0.11
chr22_19273287_19273568 0.16 CLTCL1
 clathrin, heavy chain-like 1
 5781
 0.19
chr2_236419917_236420068 0.15 AGAP1-IT1
 AGAP1 intronic transcript 1 (non-protein coding)
 5597
 0.24
chr5_6828115_6828430 0.15 ENSG00000200243
 .
 20303
 0.27
chr1_21619720_21620176 0.15 RP5-1071N3.1
165
 0.91
chrX_130875529_130875933 0.15 ENSG00000200587
 .
 197253
 0.03
chr11_119191508_119192663 0.15 ENSG00000252119
 .
 2034
 0.16
chr13_21807322_21807478 0.15 MRP63
 mitochondrial ribosomal protein 63
 56616
 0.09
chr5_38468727_38468878 0.14 CTD-2263F21.1
361
 0.86
chr15_56336229_56336380 0.14 ENSG00000239703
 .
 14125
 0.23
chr8_99960098_99960383 0.14 OSR2
 odd-skipped related transciption factor 2
 210
 0.93
chrX_130917856_130918233 0.14 ENSG00000200587
 .
 154940
 0.04
chr17_38483011_38483310 0.14 RARA
 retinoic acid receptor, alpha
 8623
 0.11
chr1_203713535_203713686 0.14 ENSG00000221643
 .
 14901
 0.15
chr13_113555280_113555431 0.14 MCF2L
 MCF.2 cell line derived transforming sequence-like
 1152
 0.51
chr9_98994971_98995126 0.14 ENSG00000265367
 .
 3156
 0.24
chr7_75911448_75912023 0.14 SRRM3
 serine/arginine repetitive matrix 3
 197
 0.93
chr17_74022610_74022808 0.14 EVPL
 envoplakin
 603
 0.59
chr22_50050359_50050996 0.14 C22orf34
 chromosome 22 open reading frame 34
 401
 0.87
chr20_43438673_43438824 0.13 RIMS4
 regulating synaptic membrane exocytosis 4
 164
 0.95
chr14_93531071_93531437 0.13 ITPK1
 inositol-tetrakisphosphate 1-kinase
 1449
 0.4
chr11_118212573_118212916 0.13 CD3D
 CD3d molecule, delta (CD3-TCR complex)
 602
 0.59
chr1_201465199_201465350 0.13 CSRP1
 cysteine and glycine-rich protein 1
 427
 0.81
chr13_114906167_114906332 0.13 RASA3
 RAS p21 protein activator 3
 8163
 0.22
chr17_15174002_15174153 0.13 PMP22
 peripheral myelin protein 22
 5434
 0.16
chr19_36500441_36500617 0.13 SYNE4
 spectrin repeat containing, nuclear envelope family member 4
 834
 0.4
chr16_85769625_85769776 0.12 ENSG00000222190
 .
 5606
 0.13
chr2_206546644_206547002 0.12 NRP2
 neuropilin 2
 401
 0.91
chr1_210517040_210517207 0.12 HHAT
 hedgehog acyltransferase
 14479
 0.23
chr5_139948767_139948946 0.12 SLC35A4
 solute carrier family 35, member A4
 4380
 0.09
chr1_32706125_32707286 0.12 MTMR9LP
 myotubularin related protein 9-like, pseudogene
 488
 0.6
chr19_41037225_41037376 0.12 SPTBN4
 spectrin, beta, non-erythrocytic 4
 905
 0.52
chr1_46982968_46983119 0.12 DMBX1
 diencephalon/mesencephalon homeobox 1
 10374
 0.15
chr20_44972040_44972274 0.12 SLC35C2
 solute carrier family 35 (GDP-fucose transporter), member C2
 14988
 0.19
chr20_1246931_1247537 0.12 SNPH
 syntaphilin
 235
 0.91
chr21_46351160_46352026 0.12 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 311
 0.78
chr1_151811855_151812405 0.12 C2CD4D
 C2 calcium-dependent domain containing 4D
 903
 0.32
chr19_35630816_35630967 0.12 FXYD1
 FXYD domain containing ion transport regulator 1
 35
 0.95
chr12_132689714_132689890 0.12 GALNT9
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
 535
 0.8
chr14_52535921_52536493 0.12 NID2
 nidogen 2 (osteonidogen)
 495
 0.84
chr1_226049341_226049492 0.12 TMEM63A
 transmembrane protein 63A
 5032
 0.15
chr11_118793309_118793854 0.12 BCL9L
 B-cell CLL/lymphoma 9-like
 3968
 0.1
chr1_88383945_88384194 0.12 ENSG00000199318
 .
 465013
 0.01
chr12_117298021_117298350 0.11 HRK
 harakiri, BCL2 interacting protein (contains only BH3 domain)
 20708
 0.2
chr14_77393350_77393819 0.11 ENSG00000223174
 .
 36978
 0.14
chr2_241949003_241950045 0.11 AC093585.6
637
 0.62
chr14_99725147_99725681 0.11 AL109767.1
3871
 0.26
chr1_154301309_154302009 0.11 ATP8B2
 ATPase, aminophospholipid transporter, class I, type 8B, member 2
 384
 0.73
chr3_66479459_66479651 0.11 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
 71801
 0.12
chr2_75904423_75904574 0.11 GCFC2
 GC-rich sequence DNA-binding factor 2
 7158
 0.13
chr1_85557311_85557759 0.11 WDR63
 WD repeat domain 63
 29525
 0.15
chr11_413234_413456 0.11 SIGIRR
 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
 1603
 0.21
chr22_50908966_50909262 0.11 SBF1
 SET binding factor 1
 4257
 0.1
chr9_92083834_92084001 0.11 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 10888
 0.23
chr9_112888297_112888507 0.11 AKAP2
 A kinase (PRKA) anchor protein 2
 621
 0.82
chr1_161038546_161039545 0.11 ARHGAP30
 Rho GTPase activating protein 30
 411
 0.65
chr17_41984276_41984918 0.11 MPP2
 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
 4
 0.96
chr2_98334586_98334804 0.11 ZAP70
 zeta-chain (TCR) associated protein kinase 70kDa
 4672
 0.2
chr16_67282110_67283381 0.11 SLC9A5
 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
 108
 0.89
chr2_236252173_236252324 0.11 ENSG00000216002
 .
 17246
 0.28
chr17_9018882_9019405 0.11 NTN1
 netrin 1
 47109
 0.15
chr2_239036083_239036322 0.11 ESPNL
 espin-like
 166
 0.94
chr7_73413897_73414048 0.11 ELN
 elastin
 28147
 0.17
chr14_94437286_94437966 0.11 ASB2
 ankyrin repeat and SOCS box containing 2
 2803
 0.22
chr10_47640131_47640292 0.11 ANTXRLP1
 anthrax toxin receptor-like pseudogene 1
 4580
 0.24
chr14_73395581_73395732 0.11 DCAF4
 DDB1 and CUL4 associated factor 4
 2461
 0.26
chr2_112433070_112433221 0.11 ENSG00000266063
 .
 95566
 0.09
chr22_33454563_33454714 0.11 SYN3
 synapsin III
 280
 0.95
chr14_96593544_96593695 0.11 ENSG00000221236
 .
 9569
 0.19
chr12_53600321_53600967 0.11 ITGB7
 integrin, beta 7
 356
 0.78
chr16_1047518_1048062 0.10 SOX8
 SRY (sex determining region Y)-box 8
 15982
 0.12
chr21_38352575_38353327 0.10 HLCS
 holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
 23
 0.97
chr17_4945612_4945862 0.10 SLC52A1
 solute carrier family 52 (riboflavin transporter), member 1
 7010
 0.09
chr3_58359199_58359350 0.10 PXK
 PX domain containing serine/threonine kinase
 22127
 0.17
chr5_134366245_134366951 0.10 PITX1
 paired-like homeodomain 1
 2227
 0.27
chr19_36004816_36005044 0.10 DMKN
 dermokine
 370
 0.74
chr17_75302303_75302454 0.10 SEPT9
 septin 9
 13219
 0.22
chr1_143466699_143467561 0.10 ENSG00000272302
 .
 29721
 0.2
chr7_73867238_73867432 0.10 GTF2IRD1
 GTF2I repeat domain containing 1
 785
 0.67
chr14_53835257_53835408 0.10 RP11-547D23.1
215260
 0.02
chr2_237551540_237552008 0.10 ACKR3
 atypical chemokine receptor 3
 73490
 0.12
chr8_67522944_67523356 0.10 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
 1992
 0.31
chr3_19030814_19030965 0.10 ENSG00000251761
 .
 34348
 0.24
chr1_162646903_162647054 0.10 DDR2
 discoidin domain receptor tyrosine kinase 2
 44718
 0.14
chr11_722189_722340 0.10 AP006621.9
4783
 0.09
chr8_125739093_125740062 0.10 MTSS1
 metastasis suppressor 1
 280
 0.94
chr8_22437078_22437527 0.10 PDLIM2
 PDZ and LIM domain 2 (mystique)
 362
 0.75
chr11_67417906_67418392 0.10 ACY3
 aspartoacylase (aminocyclase) 3
 19
 0.96
chr8_123101856_123102033 0.10 HAS2-AS1
 HAS2 antisense RNA 1
 448268
 0.01
chr1_110075008_110075602 0.10 GPR61
 G protein-coupled receptor 61
 7189
 0.1
chrX_115004520_115004902 0.10 RP1-241P17.1
47368
 0.14
chr6_134211072_134211606 0.10 TCF21
 transcription factor 21
 866
 0.5
chr16_10746808_10746959 0.10 TEKT5
 tektin 5
 37093
 0.13
chr1_20397097_20397248 0.10 PLA2G5
 phospholipase A2, group V
 471
 0.81
chr18_77163786_77163984 0.10 NFATC1
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
 3493
 0.3
chr22_17517069_17517450 0.10 GAB4
 GRB2-associated binding protein family, member 4
 28147
 0.14
chr9_73018771_73018949 0.10 KLF9
 Kruppel-like factor 9
 10680
 0.27
chr2_7570809_7570960 0.10 ENSG00000221255
 .
 146088
 0.05
chr9_136075040_136075613 0.10 OBP2B
 odorant binding protein 2B
 9302
 0.14
chr2_11884173_11884474 0.10 AC012456.4
1104
 0.39
chr16_89631829_89632776 0.10 RPL13
 ribosomal protein L13
 3524
 0.13
chr11_96073413_96073903 0.10 ENSG00000266192
 .
 944
 0.55
chr5_82863395_82863716 0.10 VCAN-AS1
 VCAN antisense RNA 1
 5422
 0.29
chr18_12011713_12011864 0.10 RP11-820I16.3
16851
 0.15
chr4_6690869_6691175 0.10 AC093323.1
 Uncharacterized protein
 3167
 0.19
chr8_22409217_22409843 0.10 SORBS3
 sorbin and SH3 domain containing 3
 322
 0.81
chr11_117859065_117859216 0.10 IL10RA
 interleukin 10 receptor, alpha
 2031
 0.32
chr6_147322190_147322415 0.10 STXBP5-AS1
 STXBP5 antisense RNA 1
 85281
 0.11
chr12_96635413_96635600 0.10 RP11-394J1.2
17755
 0.19
chr12_112438793_112438944 0.10 TMEM116
 transmembrane protein 116
 4921
 0.18
chr1_16085392_16086186 0.10 FBLIM1
 filamin binding LIM protein 1
 497
 0.68
chr15_78557114_78557783 0.10 DNAJA4
 DnaJ (Hsp40) homolog, subfamily A, member 4
 532
 0.55
chr9_133321154_133321362 0.10 ASS1
 argininosuccinate synthase 1
 879
 0.54
chr19_55983710_55983861 0.10 ZNF628
 zinc finger protein 628
 3914
 0.1
chr4_184263832_184264346 0.10 ENSG00000238596
 .
 13638
 0.14
chr19_7402613_7402882 0.10 CTB-133G6.1
11101
 0.16
chr6_147428076_147428227 0.10 STXBP5-AS1
 STXBP5 antisense RNA 1
 12448
 0.3
chr17_17817656_17817807 0.10 TOM1L2
 target of myb1-like 2 (chicken)
 42353
 0.11
chr5_67830491_67830731 0.10 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 242215
 0.02
chr7_2851005_2851785 0.10 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
 3497
 0.32
chr2_189494316_189494467 0.10 GULP1
 GULP, engulfment adaptor PTB domain containing 1
 59581
 0.15
chr16_10672917_10673068 0.09 RP11-27M24.2
952
 0.47
chr7_962027_962293 0.09 ADAP1
 ArfGAP with dual PH domains 1
 1634
 0.31
chr17_47419551_47419937 0.09 ENSG00000251964
 .
 16481
 0.12
chr1_11713861_11714012 0.09 FBXO44
 F-box protein 44
 496
 0.56
chr1_17878359_17878510 0.09 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 12104
 0.25
chr17_73522650_73522801 0.09 LLGL2
 lethal giant larvae homolog 2 (Drosophila)
 855
 0.44
chr13_113295022_113295173 0.09 C13orf35
 chromosome 13 open reading frame 35
 6261
 0.23
chr12_54402958_54403134 0.09 HOXC8
 homeobox C8
 214
 0.8
chr1_156785806_156786457 0.09 SH2D2A
 SH2 domain containing 2A
 495
 0.51
chr7_132300022_132300173 0.09 PLXNA4
 plexin A4
 33350
 0.18
chr19_42057824_42058331 0.09 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 2191
 0.27
chr22_46453843_46454104 0.09 RP6-109B7.3
3178
 0.13
chr11_35281999_35282201 0.09 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
 5192
 0.19
chr1_229335449_229335600 0.09 RP5-1061H20.5
27785
 0.17
chr14_22966536_22967037 0.09 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 10615
 0.1
chr11_62169770_62169944 0.09 SCGB1A1
 secretoglobin, family 1A, member 1 (uteroglobin)
 2718
 0.17
chr6_36281244_36281395 0.09 C6orf222
 chromosome 6 open reading frame 222
 23343
 0.15
chr1_27324350_27324577 0.09 TRNP1
 TMF1-regulated nuclear protein 1
 3653
 0.19
chr8_37552103_37552726 0.09 ZNF703
 zinc finger protein 703
 855
 0.5
chr11_36002459_36002610 0.09 RP5-916O11.2
8556
 0.2
chr6_75918243_75918708 0.09 COL12A1
 collagen, type XII, alpha 1
 2708
 0.31
chr8_99008131_99008282 0.09 MATN2
 matrilin 2
 20566
 0.15
chr17_74489731_74490033 0.09 RHBDF2
 rhomboid 5 homolog 2 (Drosophila)
 598
 0.59
chr20_17731005_17731156 0.09 BANF2
 barrier to autointegration factor 2
 50475
 0.13
chr14_103234628_103234779 0.09 TRAF3
 TNF receptor-associated factor 3
 9110
 0.19
chr14_104889660_104889811 0.09 ENSG00000222761
 .
 22350
 0.23
chr13_24828231_24828382 0.09 SPATA13-AS1
 SPATA13 antisense RNA 1
 271
 0.9
chr14_74724486_74725063 0.09 VSX2
 visual system homeobox 2
 18599
 0.14
chr7_150441383_150441534 0.09 GIMAP5
 GTPase, IMAP family member 5
 7022
 0.17
chr18_13136915_13137798 0.09 RP11-794M8.1
78968
 0.08
chr10_17034557_17035249 0.09 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 8709
 0.3
chrX_130886755_130887324 0.09 ENSG00000200587
 .
 185945
 0.03
chr14_99733165_99733625 0.09 AL109767.1
4110
 0.24
chr21_46352912_46353063 0.09 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 1083
 0.32
chr17_75453810_75454179 0.09 SEPT9
 septin 9
 1546
 0.33
chr3_194293899_194294050 0.09 TMEM44-AS1
 TMEM44 antisense RNA 1
 10766
 0.15
chr12_6901564_6902297 0.09 CD4
 CD4 molecule
 3196
 0.1
chr4_103972156_103972307 0.09 SLC9B2
 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
 6868
 0.22
chr8_28930678_28930829 0.09 CTD-2647L4.5
5957
 0.15
chr9_71736397_71737145 0.09 TJP2
 tight junction protein 2
 547
 0.84
chr2_112178560_112178711 0.09 ENSG00000266139
 .
 99967
 0.08
chr2_149627712_149627970 0.09 KIF5C
 kinesin family member 5C
 4978
 0.21
chr10_71399492_71399643 0.09 C10orf35
 chromosome 10 open reading frame 35
 9267
 0.21
chr8_135469745_135470192 0.09 ZFAT
 zinc finger and AT hook domain containing
 52457
 0.18
chr10_79613508_79613659 0.09 AL391421.1
 Uncharacterized protein; cDNA FLJ43696 fis, clone TBAES2007964
 13050
 0.18
chr20_57721681_57721954 0.09 ZNF831
 zinc finger protein 831
 44258
 0.15
chr6_27218801_27219293 0.09 PRSS16
 protease, serine, 16 (thymus)
 2332
 0.31
chr18_56530098_56530506 0.09 ZNF532
 zinc finger protein 532
 122
 0.96
chr9_96720776_96721007 0.09 BARX1
 BARX homeobox 1
 3237
 0.33
chr14_22984887_22985075 0.09 TRAJ15
 T cell receptor alpha joining 15
 13599
 0.1
chr1_207996298_207996642 0.09 ENSG00000203709
 .
 20602
 0.22
chr1_227070133_227070284 0.09 PSEN2
 presenilin 2 (Alzheimer disease 4)
 1861
 0.39
chr3_38500973_38501124 0.09 ACVR2B-AS1
 ACVR2B antisense RNA 1
 4737
 0.19
chr13_44730254_44730535 0.09 SMIM2-IT1
 SMIM2 intronic transcript 1 (non-protein coding)
 1964
 0.33
chr1_12677001_12677791 0.09 DHRS3
 dehydrogenase/reductase (SDR family) member 3
 341
 0.87
chr5_156886857_156887334 0.09 CTB-109A12.1
9
 0.54
chr3_151922835_151923340 0.09 MBNL1
 muscleblind-like splicing regulator 1
 62742
 0.13
chr17_43299697_43300109 0.09 CTD-2020K17.1
314
 0.65
chr2_85107579_85108198 0.09 TRABD2A
 TraB domain containing 2A
 318
 0.89
chr10_86300062_86300319 0.09 CCSER2
 coiled-coil serine-rich protein 2
 115495
 0.07
chr9_126807806_126807963 0.09 RP11-85O21.5
13081
 0.17
chrX_1776580_1777384 0.09 ASMT
 acetylserotonin O-methyltransferase
 21691
 0.23
chr10_99932028_99932445 0.09 R3HCC1L
 R3H domain and coiled-coil containing 1-like
 9596
 0.25
chr5_138441478_138441629 0.09 SIL1
 SIL1 nucleotide exchange factor
 25894
 0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of EBF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.1 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0072539 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0060510 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0044266 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.0 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:0072162 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.0 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.0 GO:0045683 negative regulation of epidermis development(GO:0045683)
0.0 0.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.0 GO:0061213 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0050901 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.1 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.0 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.0 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0002874 chronic inflammatory response to antigenic stimulus(GO:0002439) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.0 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0005035 death receptor activity(GO:0005035)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0015379 potassium:chloride symporter activity(GO:0015379)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1