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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for EBF3

Z-value: 1.56

Motif logo

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Transcription factors associated with EBF3

Gene Symbol Gene ID Gene Info
EBF3
ENSG00000108001.9 EBF transcription factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr10_131751845_131752016EBF3101750.3018220.941.4e-04Click!
chr10_131744784_131744954EBF3172360.2798290.909.3e-04Click!
chr10_131759230_131759381EBF328000.4044630.891.2e-03Click!
chr10_131759565_131759716EBF324650.4289190.881.7e-03Click!
chr10_131811384_131811535EBF3493540.1816870.809.7e-03Click!

Activity of the EBF3 motif across conditions

Conditions sorted by the z-value of the EBF3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_227661377_227661773 0.64 IRS1
 insulin receptor substrate 1
 2900
 0.28
chr19_50031610_50031873 0.48 RCN3
 reticulocalbin 3, EF-hand calcium binding domain
 142
 0.87
chr2_177001412_177001990 0.47 HOXD3
 homeobox D3
 16
 0.5
chr3_100711576_100712203 0.46 ABI3BP
 ABI family, member 3 (NESH) binding protein
 408
 0.89
chr16_86020719_86020879 0.44 IRF8
 interferon regulatory factor 8
 72880
 0.11
chr17_29887299_29887674 0.42 ENSG00000207614
 .
 471
 0.69
chr18_77225876_77226142 0.41 AC018445.1
 Uncharacterized protein
 50048
 0.15
chr5_95768411_95768678 0.41 PCSK1
 proprotein convertase subtilisin/kexin type 1
 440
 0.89
chrX_17394576_17394820 0.40 NHS
 Nance-Horan syndrome (congenital cataracts and dental anomalies)
 1155
 0.54
chr3_61548960_61549133 0.39 PTPRG
 protein tyrosine phosphatase, receptor type, G
 1461
 0.59
chr2_176987899_176988234 0.39 HOXD9
 homeobox D9
 978
 0.29
chr9_129883603_129883754 0.38 ANGPTL2
 angiopoietin-like 2
 1235
 0.56
chr4_81195995_81196185 0.38 FGF5
 fibroblast growth factor 5
 8297
 0.25
chr1_168698177_168698379 0.38 DPT
 dermatopontin
 224
 0.95
chr2_230035602_230035855 0.37 PID1
 phosphotyrosine interaction domain containing 1
 61073
 0.14
chr14_69419495_69419882 0.37 ACTN1
 actinin, alpha 1
 5423
 0.25
chr20_56749874_56750278 0.37 C20orf85
 chromosome 20 open reading frame 85
 24116
 0.19
chr16_88471986_88472161 0.37 ZNF469
 zinc finger protein 469
 21806
 0.18
chr7_73183095_73183263 0.37 CLDN3
 claudin 3
 1421
 0.3
chr20_39969728_39969901 0.37 LPIN3
 lipin 3
 254
 0.92
chr9_126803162_126803381 0.36 RP11-85O21.5
8468
 0.18
chr8_49831422_49831573 0.36 SNAI2
 snail family zinc finger 2
 2491
 0.43
chr3_170139818_170139969 0.36 CLDN11
 claudin 11
 3038
 0.33
chr12_110270768_110271158 0.35 ENSG00000263510
 .
 190
 0.56
chr11_132813237_132813595 0.35 OPCML
 opioid binding protein/cell adhesion molecule-like
 150
 0.98
chr17_41613761_41613953 0.35 ETV4
 ets variant 4
 6055
 0.15
chr18_21851258_21851803 0.35 OSBPL1A
 oxysterol binding protein-like 1A
 666
 0.6
chr12_96183320_96183471 0.34 NTN4
 netrin 4
 331
 0.86
chr2_177000583_177000734 0.34 HOXD3
 homeobox D3
 1027
 0.23
chr2_3465758_3466116 0.34 TRAPPC12
 trafficking protein particle complex 12
 3507
 0.21
chr19_49219826_49219992 0.34 MAMSTR
 MEF2 activating motif and SAP domain containing transcriptional regulator
 191
 0.87
chr18_59401096_59401293 0.33 RNF152
 ring finger protein 152
 159798
 0.04
chr1_41962190_41962352 0.33 EDN2
 endothelin 2
 11929
 0.2
chr9_137535529_137535696 0.33 COL5A1
 collagen, type V, alpha 1
 1992
 0.35
chr16_4422135_4423224 0.33 VASN
 vasorin
 830
 0.49
chr1_203456320_203456508 0.33 OPTC
 opticin
 6857
 0.22
chr13_24477780_24477964 0.33 C1QTNF9B
 C1q and tumor necrosis factor related protein 9B
 1078
 0.48
chr9_14924390_14924574 0.33 FREM1
 FRAS1 related extracellular matrix 1
 13489
 0.26
chr7_101579659_101580126 0.33 CTB-181H17.1
23504
 0.22
chr12_54395536_54395687 0.33 HOXC9
 homeobox C9
 1708
 0.12
chr13_113555280_113555431 0.33 MCF2L
 MCF.2 cell line derived transforming sequence-like
 1152
 0.51
chr7_143208334_143208676 0.32 TAS2R41
 taste receptor, type 2, member 41
 33539
 0.13
chr10_86300062_86300319 0.32 CCSER2
 coiled-coil serine-rich protein 2
 115495
 0.07
chr14_20903201_20903901 0.32 KLHL33
 kelch-like family member 33
 250
 0.81
chr11_46307086_46307288 0.32 CREB3L1
 cAMP responsive element binding protein 3-like 1
 7959
 0.18
chr10_27914063_27914342 0.32 MKX
 mohawk homeobox
 118272
 0.05
chr8_6539884_6540241 0.32 CTD-2541M15.1
25638
 0.18
chr19_34973467_34973843 0.32 WTIP
 Wilms tumor 1 interacting protein
 222
 0.92
chr15_42749089_42749416 0.31 ZNF106
 zinc finger protein 106
 459
 0.78
chr7_157071827_157072074 0.31 ENSG00000266453
 .
 26537
 0.21
chr1_40598519_40598964 0.31 RLF
 rearranged L-myc fusion
 28304
 0.14
chr7_155049844_155050012 0.31 INSIG1
 insulin induced gene 1
 39558
 0.15
chr17_70113469_70114161 0.31 SOX9
 SRY (sex determining region Y)-box 9
 3346
 0.37
chr1_201619846_201619997 0.30 NAV1
 neuron navigator 1
 2471
 0.24
chr19_36500441_36500617 0.30 SYNE4
 spectrin repeat containing, nuclear envelope family member 4
 834
 0.4
chr18_47172272_47172498 0.30 LIPG
 lipase, endothelial
 83670
 0.07
chr19_13618302_13618480 0.30 CACNA1A
 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
 1074
 0.61
chr3_126398343_126398521 0.30 TXNRD3
 thioredoxin reductase 3
 24434
 0.17
chr19_49661333_49661989 0.30 TRPM4
 transient receptor potential cation channel, subfamily M, member 4
 562
 0.58
chr10_69867536_69867687 0.30 MYPN
 myopalladin
 1383
 0.44
chr22_46453843_46454104 0.30 RP6-109B7.3
3178
 0.13
chr4_111397812_111398104 0.30 ENPEP
 glutamyl aminopeptidase (aminopeptidase A)
 729
 0.72
chr3_126006139_126006425 0.30 KLF15
 Kruppel-like factor 15
 70003
 0.08
chr9_116327712_116328152 0.29 RGS3
 regulator of G-protein signaling 3
 571
 0.8
chr11_61657871_61658132 0.29 FADS3
 fatty acid desaturase 3
 852
 0.49
chr15_96903147_96903373 0.29 AC087477.1
 Uncharacterized protein
 1227
 0.45
chr20_5484666_5484886 0.29 RP5-1022P6.5
29498
 0.21
chr7_130070545_130070874 0.29 CEP41
 centrosomal protein 41kDa
 3889
 0.17
chr6_136360177_136360429 0.29 RP13-143G15.3
25473
 0.21
chr9_102828891_102829115 0.29 ERP44
 endoplasmic reticulum protein 44
 32319
 0.16
chr19_46916092_46916684 0.29 CCDC8
 coiled-coil domain containing 8
 453
 0.75
chr5_82863395_82863716 0.29 VCAN-AS1
 VCAN antisense RNA 1
 5422
 0.29
chr1_1355307_1355467 0.29 RP4-758J18.7
238
 0.74
chr9_137534558_137534843 0.28 COL5A1
 collagen, type V, alpha 1
 1080
 0.55
chr19_19050618_19051263 0.28 HOMER3
 homer homolog 3 (Drosophila)
 173
 0.5
chr16_67634950_67635107 0.28 AC009095.4
14217
 0.09
chr15_71148348_71148634 0.28 LARP6
 La ribonucleoprotein domain family, member 6
 1993
 0.26
chr8_19459992_19460252 0.28 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
 116
 0.98
chr2_9879900_9880051 0.28 ENSG00000200034
 .
 937
 0.66
chr11_27720868_27721098 0.28 BDNF
 brain-derived neurotrophic factor
 231
 0.95
chr6_3517843_3518042 0.28 SLC22A23
 solute carrier family 22, member 23
 60686
 0.14
chr2_145278908_145279072 0.28 ZEB2
 zinc finger E-box binding homeobox 2
 369
 0.75
chr17_75318226_75318377 0.28 SEPT9
 septin 9
 391
 0.88
chr3_64670816_64671530 0.28 ADAMTS9-AS2
 ADAMTS9 antisense RNA 2
 369
 0.87
chr1_23079970_23080247 0.28 ENSG00000216157
 .
 4704
 0.19
chr14_24803093_24804202 0.28 ADCY4
 adenylate cyclase 4
 306
 0.72
chrX_17393577_17393934 0.28 NHS
 Nance-Horan syndrome (congenital cataracts and dental anomalies)
 212
 0.95
chr9_89558891_89559042 0.27 GAS1
 growth arrest-specific 1
 3138
 0.4
chr17_65486818_65487236 0.27 ENSG00000207688
 .
 19422
 0.14
chr2_172448669_172448823 0.27 CYBRD1
 cytochrome b reductase 1
 69157
 0.11
chr4_86398617_86398768 0.27 ARHGAP24
 Rho GTPase activating protein 24
 2301
 0.46
chr1_226001327_226001516 0.27 EPHX1
 epoxide hydrolase 1, microsomal (xenobiotic)
 3585
 0.18
chr3_38071745_38071896 0.27 PLCD1
 phospholipase C, delta 1
 567
 0.68
chr17_76330950_76331176 0.27 SOCS3
 suppressor of cytokine signaling 3
 25092
 0.13
chr14_25518126_25518277 0.27 STXBP6
 syntaxin binding protein 6 (amisyn)
 5
 0.99
chr19_4575354_4575624 0.27 SEMA6B
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
 15669
 0.1
chr17_56494859_56495034 0.27 RNF43
 ring finger protein 43
 3
 0.97
chr17_12888079_12888251 0.27 ARHGAP44
 Rho GTPase activating protein 44
 4740
 0.18
chr1_31380843_31381078 0.27 SDC3
 syndecan 3
 648
 0.66
chr2_200320371_200320723 0.27 SATB2
 SATB homeobox 2
 264
 0.92
chr17_25821548_25821771 0.27 KSR1
 kinase suppressor of ras 1
 22623
 0.18
chr8_26308983_26309354 0.27 RP11-14I17.3
11161
 0.19
chr2_151342879_151343387 0.27 RND3
 Rho family GTPase 3
 1048
 0.71
chr20_17875766_17876211 0.26 ENSG00000212555
 .
 8418
 0.2
chr14_103522624_103522803 0.26 CDC42BPB
 CDC42 binding protein kinase beta (DMPK-like)
 1086
 0.51
chr19_47921712_47921897 0.26 MEIS3
 Meis homeobox 3
 575
 0.72
chr11_19617803_19618188 0.26 ENSG00000207407
 .
 5157
 0.23
chrX_53349214_53349365 0.26 IQSEC2
 IQ motif and Sec7 domain 2
 1233
 0.43
chr20_56622065_56622292 0.26 ENSG00000221385
 .
 20334
 0.22
chr19_46270378_46270670 0.26 AC074212.6
530
 0.46
chr16_46663412_46663563 0.26 SHCBP1
 SHC SH2-domain binding protein 1
 7949
 0.18
chr2_128439019_128439205 0.26 LIMS2
 LIM and senescent cell antigen-like domains 2
 248
 0.91
chr19_16436739_16437476 0.26 KLF2
 Kruppel-like factor 2
 1456
 0.3
chr16_53451316_53451467 0.26 RBL2
 retinoblastoma-like 2 (p130)
 16498
 0.15
chr18_9594992_9595154 0.26 RP11-881L2.1
7689
 0.17
chr12_49741682_49741986 0.25 DNAJC22
 DnaJ (Hsp40) homolog, subfamily C, member 22
 1013
 0.39
chr16_65154751_65155029 0.25 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 943
 0.75
chr8_97506014_97506898 0.25 SDC2
 syndecan 2
 220
 0.96
chr3_73673186_73673337 0.25 PDZRN3-AS1
 PDZRN3 antisense RNA 1
 542
 0.56
chr10_118500836_118501537 0.25 HSPA12A
 heat shock 70kDa protein 12A
 899
 0.64
chr6_39614678_39614962 0.25 KIF6
 kinesin family member 6
 7361
 0.26
chr17_38500769_38502147 0.25 RARA
 retinoic acid receptor, alpha
 35
 0.95
chr19_4058568_4058732 0.25 CTD-2622I13.3
4097
 0.13
chr19_3404785_3405081 0.25 NFIC
 nuclear factor I/C (CCAAT-binding transcription factor)
 38349
 0.11
chr14_87325066_87325217 0.25 RP11-322L20.1
 HCG2028865; Uncharacterized protein
 46981
 0.21
chr2_9953892_9954060 0.25 TAF1B
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
 29507
 0.19
chr2_223919112_223919263 0.25 KCNE4
 potassium voltage-gated channel, Isk-related family, member 4
 2325
 0.41
chr1_201436884_201437966 0.25 PHLDA3
 pleckstrin homology-like domain, family A, member 3
 887
 0.55
chr6_127440959_127441265 0.24 RSPO3
 R-spondin 3
 929
 0.72
chr9_88861790_88861958 0.24 ENSG00000223012
 .
 11687
 0.19
chr3_65342341_65342492 0.24 RP11-88H12.2
2976
 0.39
chr7_47367963_47368180 0.24 TNS3
 tensin 3
 48155
 0.2
chr10_74878153_74878313 0.24 RP11-152N13.16
6930
 0.1
chr19_14606640_14606859 0.24 GIPC1
 GIPC PDZ domain containing family, member 1
 195
 0.89
chr17_15016441_15016644 0.24 ENSG00000238806
 .
 124658
 0.05
chr5_134366245_134366951 0.24 PITX1
 paired-like homeodomain 1
 2227
 0.27
chr19_524423_524574 0.24 CDC34
 cell division cycle 34
 7216
 0.09
chr7_99835180_99835357 0.24 ENSG00000222482
 .
 17525
 0.08
chr1_88383945_88384194 0.24 ENSG00000199318
 .
 465013
 0.01
chr22_24383812_24383984 0.24 GSTT1
 glutathione S-transferase theta 1
 344
 0.8
chr1_149908154_149908323 0.24 MTMR11
 myotubularin related protein 11
 5
 0.95
chr10_102278895_102279852 0.24 SEC31B
 SEC31 homolog B (S. cerevisiae)
 218
 0.92
chr19_47524215_47524432 0.24 NPAS1
 neuronal PAS domain protein 1
 180
 0.94
chr19_46117807_46118118 0.24 EML2
 echinoderm microtubule associated protein like 2
 4386
 0.11
chr7_97839825_97840267 0.24 BHLHA15
 basic helix-loop-helix family, member a15
 693
 0.72
chr18_60845880_60846088 0.24 ENSG00000238988
 .
 15914
 0.21
chr1_227635446_227635597 0.24 ENSG00000202264
 .
 113361
 0.06
chr19_55795582_55795793 0.24 BRSK1
 BR serine/threonine kinase 1
 102
 0.92
chr6_5498160_5498518 0.24 RP1-232P20.1
40031
 0.2
chr14_69015576_69015827 0.24 CTD-2325P2.4
79461
 0.1
chr12_121345014_121345220 0.24 SPPL3
 signal peptide peptidase like 3
 2943
 0.25
chr22_33698264_33698426 0.24 SC22CB-1D7.1
18506
 0.25
chr10_93472068_93472249 0.23 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
 79347
 0.09
chr14_69950443_69950594 0.23 PLEKHD1
 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
 953
 0.65
chr17_75319506_75319975 0.23 SEPT9
 septin 9
 1048
 0.58
chr1_156659032_156659371 0.23 NES
 nestin
 12012
 0.08
chr10_84741142_84741483 0.23 ENSG00000200774
 .
 86515
 0.11
chr6_1575620_1576144 0.23 FOXC1
 forkhead box C1
 34799
 0.21
chr10_92680065_92680221 0.23 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
 890
 0.55
chr3_184301056_184301262 0.23 EPHB3
 EPH receptor B3
 21587
 0.18
chr15_77788917_77789110 0.23 HMG20A
 high mobility group 20A
 18378
 0.24
chr5_142592854_142593005 0.23 ARHGAP26
 Rho GTPase activating protein 26
 6164
 0.27
chr3_134050593_134051228 0.23 AMOTL2
 angiomotin like 2
 39844
 0.16
chrX_67867525_67867904 0.23 STARD8
 StAR-related lipid transfer (START) domain containing 8
 104
 0.98
chr7_18810538_18810689 0.23 ENSG00000222164
 .
 37289
 0.22
chr3_184893391_184893626 0.23 EHHADH-AS1
 EHHADH antisense RNA 1
 12819
 0.2
chr12_127867879_127868128 0.23 ENSG00000253089
 .
 62103
 0.16
chr4_41015538_41015689 0.23 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 789
 0.67
chr5_71453247_71453481 0.23 ENSG00000264099
 .
 11930
 0.23
chr5_64438498_64438671 0.23 ENSG00000207439
 .
 19388
 0.29
chr15_45933944_45934448 0.23 SQRDL
 sulfide quinone reductase-like (yeast)
 3883
 0.22
chr15_81072135_81072315 0.23 KIAA1199
 KIAA1199
 513
 0.83
chr1_9257961_9258177 0.23 H6PD
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
 36765
 0.13
chr2_239036083_239036322 0.23 ESPNL
 espin-like
 166
 0.94
chr2_238321225_238321570 0.23 COL6A3
 collagen, type VI, alpha 3
 1394
 0.45
chrX_139846676_139846867 0.23 CDR1
 cerebellar degeneration-related protein 1, 34kDa
 19952
 0.22
chr20_45583383_45583578 0.23 EYA2
 eyes absent homolog 2 (Drosophila)
 35160
 0.2
chr1_211306419_211307099 0.23 KCNH1-IT1
 KCNH1 intronic transcript 1 (non-protein coding)
 43
 0.92
chr11_8740394_8740932 0.22 ST5
 suppression of tumorigenicity 5
 27
 0.96
chr5_138289219_138289395 0.22 CTNNA1
 catenin (cadherin-associated protein), alpha 1, 102kDa
 22980
 0.17
chr7_1028148_1028407 0.22 CYP2W1
 cytochrome P450, family 2, subfamily W, polypeptide 1
 1984
 0.21
chr12_54430598_54430749 0.22 ENSG00000207571
 .
 2939
 0.1
chr15_23454167_23454360 0.22 ENSG00000238347
 .
 9495
 0.15
chr11_66102741_66104078 0.22 RIN1
 Ras and Rab interactor 1
 468
 0.53
chr1_210517040_210517207 0.22 HHAT
 hedgehog acyltransferase
 14479
 0.23
chr11_8739823_8739992 0.22 ST5
 suppression of tumorigenicity 5
 117
 0.94
chr11_89867468_89867846 0.22 NAALAD2
 N-acetylated alpha-linked acidic dipeptidase 2
 40
 0.98
chr17_78194664_78195096 0.22 SGSH
 N-sulfoglucosamine sulfohydrolase
 158
 0.63
chr12_106533400_106533896 0.22 NUAK1
 NUAK family, SNF1-like kinase, 1
 163
 0.97
chr10_52750817_52751095 0.22 PRKG1
 protein kinase, cGMP-dependent, type I
 11
 0.99
chr9_16867910_16868386 0.22 BNC2
 basonuclin 2
 2556
 0.42
chr16_2210764_2211128 0.22 TRAF7
 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
 2597
 0.09
chr10_119294315_119294466 0.22 EMX2OS
 EMX2 opposite strand/antisense RNA
 7440
 0.24
chr4_121991394_121991545 0.22 NDNF
 neuron-derived neurotrophic factor
 1687
 0.41
chr16_54970178_54971110 0.22 IRX5
 iroquois homeobox 5
 4660
 0.36
chr17_1903139_1903290 0.22 CTD-2545H1.2
4306
 0.12
chr16_80972630_80972781 0.22 CMC2
 C-x(9)-C motif containing 2
 59559
 0.09
chr8_21990263_21990450 0.22 HR
 hair growth associated
 975
 0.39
chr10_90710785_90711179 0.22 ACTA2
 actin, alpha 2, smooth muscle, aorta
 1548
 0.33
chr2_120189004_120189226 0.22 TMEM37
 transmembrane protein 37
 330
 0.89

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of EBF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.3 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.3 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1 0.3 GO:0045112 integrin biosynthetic process(GO:0045112)
0.1 0.3 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.4 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.2 GO:0032351 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.6 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0060602 branch elongation of an epithelium(GO:0060602)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.0 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.4 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:1990845 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0060444 branching involved in mammary gland duct morphogenesis(GO:0060444)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.2 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0060603 mammary gland duct morphogenesis(GO:0060603)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.3 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.0 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:1904748 regulation of apoptotic process involved in morphogenesis(GO:1902337) regulation of apoptotic process involved in development(GO:1904748)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.0 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.0 GO:0060536 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0072538 T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.0 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.0 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.2 GO:0035195 gene silencing by miRNA(GO:0035195)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.4 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0052509 modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.0 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0003407 neural retina development(GO:0003407)
0.0 0.0 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.0 0.0 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0061042 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.0 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0044217 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.0 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.1 GO:0005925 focal adhesion(GO:0005925)
0.0 2.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043559 insulin binding(GO:0043559)
0.1 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0004470 malic enzyme activity(GO:0004470)
0.1 0.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.4 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.2 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation