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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ELF3_EHF

Z-value: 1.19

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Transcription factors associated with ELF3_EHF

Gene Symbol Gene ID Gene Info
ELF3
ENSG00000163435.11 E74 like ETS transcription factor 3
EHF
ENSG00000135373.8 ETS homologous factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_34653922_34654073EHF140.9872650.818.6e-03Click!
chr11_34666501_34666652EHF24020.4128600.723.0e-02Click!
chr11_34654877_34655028EHF9410.6989740.646.5e-02Click!
chr11_34646975_34647126EHF12270.6031990.627.6e-02Click!
chr11_34653140_34653291EHF7960.7534270.608.5e-02Click!
chr1_201977190_201977341ELF31920.8800640.009.9e-01Click!

Activity of the ELF3_EHF motif across conditions

Conditions sorted by the z-value of the ELF3_EHF motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_70244216_70245100 0.71 CTTN
 cortactin
 11
 0.53
chr13_114103770_114104137 0.68 ADPRHL1
 ADP-ribosylhydrolase like 1
 361
 0.83
chr16_77224906_77225760 0.68 MON1B
 MON1 secretory trafficking family member B
 236
 0.93
chr13_114103239_114103495 0.56 ADPRHL1
 ADP-ribosylhydrolase like 1
 90
 0.96
chr2_161826657_161826810 0.52 ENSG00000244372
 .
 92675
 0.09
chr8_49622141_49622390 0.47 EFCAB1
 EF-hand calcium binding domain 1
 20083
 0.28
chr2_241949003_241950045 0.46 AC093585.6
637
 0.62
chr10_15138786_15140121 0.45 RPP38
 ribonuclease P/MRP 38kDa subunit
 34
 0.62
chr13_30251628_30251779 0.45 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 81878
 0.11
chr6_116382044_116382245 0.43 FRK
 fyn-related kinase
 223
 0.94
chr22_19165246_19166141 0.43 SLC25A1
 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
 341
 0.82
chr11_7599067_7599755 0.42 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
 1140
 0.49
chr4_177930767_177930918 0.40 ENSG00000222859
 .
 171754
 0.03
chr6_137555100_137555380 0.39 IFNGR1
 interferon gamma receptor 1
 14654
 0.26
chr13_51483605_51485004 0.39 RNASEH2B
 ribonuclease H2, subunit B
 412
 0.48
chr18_56604719_56604870 0.39 ENSG00000251870
 .
 11266
 0.21
chr5_150273550_150273701 0.38 ZNF300
 zinc finger protein 300
 10726
 0.19
chr10_118764443_118765166 0.38 KIAA1598
 KIAA1598
 72
 0.98
chr20_3189609_3190930 0.37 ITPA
 inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
 98
 0.95
chr1_224712859_224713133 0.37 WDR26
 WD repeat domain 26
 88261
 0.07
chr13_67804057_67805835 0.36 PCDH9
 protocadherin 9
 478
 0.9
chr22_30831807_30831958 0.36 MTFP1
 mitochondrial fission process 1
 10077
 0.07
chr10_15411519_15412658 0.35 FAM171A1
 family with sequence similarity 171, member A1
 970
 0.7
chr11_118794725_118796211 0.35 BCL9L
 B-cell CLL/lymphoma 9-like
 5855
 0.09
chr1_214397865_214398571 0.35 SMYD2
 SET and MYND domain containing 2
 56358
 0.16
chr17_48714816_48714967 0.35 ABCC3
 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
 2673
 0.17
chr5_140562606_140562757 0.34 PCDHB16
 protocadherin beta 16
 1701
 0.15
chr5_54455785_54456014 0.34 GPX8
 glutathione peroxidase 8 (putative)
 47
 0.96
chr13_26312101_26312591 0.33 AL138815.1
 Uncharacterized protein
 129715
 0.05
chr2_228683348_228683499 0.33 CCL20
 chemokine (C-C motif) ligand 20
 4853
 0.24
chr10_71988541_71988692 0.32 PPA1
 pyrophosphatase (inorganic) 1
 4544
 0.24
chr2_128492018_128492224 0.32 SFT2D3
 SFT2 domain containing 3
 33524
 0.13
chr10_10836310_10836461 0.32 CELF2
 CUGBP, Elav-like family member 2
 210874
 0.02
chr6_1960344_1960495 0.32 GMDS
 GDP-mannose 4,6-dehydratase
 215806
 0.02
chr5_167793292_167793676 0.32 WWC1
 WW and C2 domain containing 1
 4942
 0.3
chr12_80747054_80747205 0.32 OTOGL
 otogelin-like
 3005
 0.29
chr2_43986075_43986259 0.32 ENSG00000252490
 .
 13322
 0.19
chr7_150779695_150780926 0.32 TMUB1
 transmembrane and ubiquitin-like domain containing 1
 9
 0.94
chr14_55571041_55571192 0.31 LGALS3
 lectin, galactoside-binding, soluble, 3
 19712
 0.19
chr7_128021355_128021506 0.31 PRRT4
 proline-rich transmembrane protein 4
 19691
 0.12
chr3_105848938_105849089 0.31 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 260617
 0.02
chr3_126725218_126725369 0.31 PLXNA1
 plexin A1
 17856
 0.27
chr4_19741105_19741415 0.31 SLIT2
 slit homolog 2 (Drosophila)
 513623
 0.0
chr6_170604225_170605407 0.31 FAM120B
 family with sequence similarity 120B
 407
 0.83
chr12_1905695_1906675 0.30 CACNA2D4
 calcium channel, voltage-dependent, alpha 2/delta subunit 4
 14701
 0.2
chr2_26367902_26368120 0.30 GAREML
 GRB2 associated, regulator of MAPK1-like
 27949
 0.17
chr2_23627518_23627754 0.30 KLHL29
 kelch-like family member 29
 19548
 0.28
chr9_96218955_96219106 0.30 FAM120AOS
 family with sequence similarity 120A opposite strand
 3156
 0.18
chr21_15922641_15922820 0.30 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 4066
 0.28
chr16_578205_579384 0.30 CAPN15
 calpain 15
 938
 0.34
chr6_117587237_117587388 0.30 VGLL2
 vestigial like 2 (Drosophila)
 575
 0.77
chr20_1892396_1892547 0.30 SIRPA
 signal-regulatory protein alpha
 16529
 0.21
chr22_46476344_46476543 0.30 FLJ27365
 hsa-mir-4763
 251
 0.85
chr6_83073574_83074143 0.29 TPBG
 trophoblast glycoprotein
 103
 0.98
chr2_83156543_83156694 0.29 ENSG00000201311
 .
 622326
 0.0
chr2_53795780_53795969 0.29 ENSG00000207456
 .
 1743
 0.47
chr8_97172057_97172969 0.29 GDF6
 growth differentiation factor 6
 507
 0.84
chr3_22187235_22187386 0.29 ENSG00000221384
 .
 316080
 0.01
chr14_50505887_50506056 0.29 ENSG00000201358
 .
 29315
 0.13
chr5_109632882_109633033 0.29 ENSG00000221436
 .
 216659
 0.02
chr17_62705322_62705475 0.29 SMURF2
 SMAD specific E3 ubiquitin protein ligase 2
 47212
 0.12
chr6_1798117_1798268 0.28 FOXC1
 forkhead box C1
 187511
 0.03
chr12_53693277_53694636 0.28 C12orf10
 chromosome 12 open reading frame 10
 79
 0.58
chr2_28817013_28817303 0.28 PLB1
 phospholipase B1
 7628
 0.24
chr2_203881741_203882170 0.28 NBEAL1
 neurobeachin-like 1
 2353
 0.35
chr4_84772402_84772553 0.28 ENSG00000201633
 .
 215034
 0.02
chr6_136417248_136417399 0.28 RP13-143G15.3
23358
 0.2
chr6_150246697_150247451 0.28 RAET1G
 retinoic acid early transcript 1G
 2817
 0.17
chr12_51640112_51640647 0.28 DAZAP2
 DAZ associated protein 2
 7300
 0.14
chr10_92616661_92616812 0.28 HTR7
 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
 719
 0.67
chr3_13869046_13869197 0.28 WNT7A
 wingless-type MMTV integration site family, member 7A
 52497
 0.13
chr15_35283823_35284080 0.28 ZNF770
 zinc finger protein 770
 3463
 0.25
chr11_61447475_61447708 0.28 DAGLA
 diacylglycerol lipase, alpha
 314
 0.89
chr14_103389080_103389600 0.27 AMN
 amnion associated transmembrane protein
 347
 0.84
chr18_37368450_37368601 0.27 ENSG00000212354
 .
 109939
 0.07
chr10_18126007_18126187 0.27 ENSG00000207938
 .
 7939
 0.2
chr2_217204685_217204878 0.27 ENSG00000207303
 .
 11345
 0.17
chr15_71184312_71185443 0.27 LRRC49
 leucine rich repeat containing 49
 88
 0.55
chr19_55862099_55862250 0.27 COX6B2
 cytochrome c oxidase subunit VIb polypeptide 2 (testis)
 3734
 0.08
chr5_106900739_106900890 0.27 EFNA5
 ephrin-A5
 105514
 0.08
chr6_37227035_37227379 0.27 TBC1D22B
 TBC1 domain family, member 22B
 1659
 0.28
chr14_35400431_35400683 0.27 ENSG00000199980
 .
 2192
 0.28
chr1_11850709_11850962 0.27 C1orf167
 chromosome 1 open reading frame 167
 10961
 0.11
chr8_145925356_145925968 0.26 AF186192.5
5257
 0.15
chr17_15870184_15870534 0.26 ADORA2B
 adenosine A2b receptor
 22128
 0.14
chr17_38255735_38256962 0.26 NR1D1
 nuclear receptor subfamily 1, group D, member 1
 630
 0.6
chr2_135105545_135105696 0.26 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 93790
 0.09
chr10_69865396_69865547 0.26 MYPN
 myopalladin
 441
 0.84
chr10_375832_375983 0.26 DIP2C
 DIP2 disco-interacting protein 2 homolog C (Drosophila)
 441
 0.85
chr5_52367762_52367913 0.26 CTD-2366F13.2
17461
 0.19
chr2_28672824_28673107 0.26 PLB1
 phospholipase B1
 7047
 0.22
chr2_23603831_23604295 0.26 KLHL29
 kelch-like family member 29
 4025
 0.36
chr13_107137023_107137174 0.26 EFNB2
 ephrin-B2
 50364
 0.17
chr5_176074525_176075535 0.26 TSPAN17
 tetraspanin 17
 409
 0.77
chr17_2612430_2612749 0.26 CLUH
 clustered mitochondria (cluA/CLU1) homolog
 1903
 0.21
chr1_33207592_33208218 0.25 KIAA1522
 KIAA1522
 419
 0.8
chr3_9446443_9446669 0.25 SETD5-AS1
 SETD5 antisense RNA 1
 6293
 0.15
chr18_31738936_31739121 0.25 NOL4
 nucleolar protein 4
 63028
 0.13
chr19_55791240_55791709 0.25 HSPBP1
 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
 5
 0.94
chr2_18093683_18093834 0.25 KCNS3
 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
 33108
 0.21
chr9_34663128_34663279 0.25 CCL27
 chemokine (C-C motif) ligand 27
 514
 0.56
chr7_17720120_17720505 0.25 SNX13
 sorting nexin 13
 259779
 0.02
chr10_33622786_33623487 0.25 NRP1
 neuropilin 1
 174
 0.97
chr10_12376015_12376474 0.25 ENSG00000264036
 .
 5856
 0.19
chr4_86419636_86419834 0.25 ARHGAP24
 Rho GTPase activating protein 24
 23344
 0.28
chr3_184504176_184504876 0.25 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
 25405
 0.22
chr3_189348802_189349006 0.24 TP63
 tumor protein p63
 312
 0.95
chr9_97785492_97785727 0.24 C9orf3
 chromosome 9 open reading frame 3
 18331
 0.17
chr1_27884100_27884415 0.24 RP1-159A19.4
31941
 0.12
chr17_39673114_39673265 0.24 KRT15
 keratin 15
 1527
 0.2
chr4_184922100_184922251 0.24 STOX2
 storkhead box 2
 303
 0.92
chr3_54121860_54122011 0.24 CACNA2D3
 calcium channel, voltage-dependent, alpha 2/delta subunit 3
 34639
 0.22
chr15_71373754_71373905 0.24 THSD4
 thrombospondin, type I, domain containing 4
 15462
 0.22
chrX_23815798_23815949 0.24 SAT1
 spermidine/spermine N1-acetyltransferase 1
 14583
 0.14
chr9_25677269_25678110 0.24 TUSC1
 tumor suppressor candidate 1
 1167
 0.68
chr7_100660155_100661047 0.24 RP11-395B7.4
281
 0.85
chr11_27485860_27486011 0.24 RP11-159H22.2
7341
 0.17
chr6_106994445_106994613 0.24 AIM1
 absent in melanoma 1
 5500
 0.23
chr14_103394355_103395516 0.24 AMN
 amnion associated transmembrane protein
 211
 0.92
chr11_44338057_44338887 0.24 ALX4
 ALX homeobox 4
 6756
 0.31
chr3_50194015_50194506 0.24 RP11-493K19.3
742
 0.47
chr1_44513271_44513499 0.24 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
 16251
 0.14
chr4_81189966_81190509 0.24 FGF5
 fibroblast growth factor 5
 2444
 0.36
chr3_113616260_113616494 0.24 GRAMD1C
 GRAM domain containing 1C
 38
 0.98
chr2_103405948_103406099 0.24 TMEM182
 transmembrane protein 182
 27551
 0.22
chr2_64821582_64821733 0.24 ENSG00000252414
 .
 15631
 0.2
chr22_38452981_38453959 0.24 PICK1
 protein interacting with PRKCA 1
 56
 0.95
chr5_167646669_167646982 0.24 CTB-178M22.2
12537
 0.22
chr18_21407330_21407481 0.23 LAMA3
 laminin, alpha 3
 6512
 0.26
chr12_6798179_6798744 0.23 ZNF384
 zinc finger protein 384
 2
 0.94
chr19_2014732_2015442 0.23 BTBD2
 BTB (POZ) domain containing 2
 632
 0.54
chr5_58817449_58817600 0.23 PDE4D
 phosphodiesterase 4D, cAMP-specific
 64695
 0.15
chr6_12314255_12314578 0.23 EDN1
 endothelin 1
 23820
 0.26
chr6_27263961_27264170 0.23 POM121L2
 POM121 transmembrane nucleoporin-like 2
 15026
 0.2
chr14_20928526_20929515 0.23 TMEM55B
 transmembrane protein 55B
 32
 0.94
chr11_8829373_8829660 0.23 ST5
 suppression of tumorigenicity 5
 2680
 0.22
chr19_12780320_12781072 0.23 WDR83
 WD repeat domain 83
 179
 0.62
chr3_134261428_134261579 0.23 CEP63
 centrosomal protein 63kDa
 3495
 0.28
chr1_147148877_147149210 0.23 ACP6
 acid phosphatase 6, lysophosphatidic
 6425
 0.22
chr2_196444875_196445026 0.23 SLC39A10
 solute carrier family 39 (zinc transporter), member 10
 4249
 0.31
chr20_32856950_32857430 0.23 ASIP
 agouti signaling protein
 9019
 0.15
chrX_129473317_129474471 0.23 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
 7
 0.98
chrX_54947220_54948504 0.23 TRO
 trophinin
 41
 0.97
chrX_129838124_129838315 0.23 ENOX2
 ecto-NOX disulfide-thiol exchanger 2
 5068
 0.34
chr9_112674232_112674383 0.22 PALM2
 paralemmin 2
 44996
 0.18
chr20_1874240_1874814 0.22 SIRPA
 signal-regulatory protein alpha
 627
 0.78
chr1_2187001_2187152 0.22 SKI
 v-ski avian sarcoma viral oncogene homolog
 26942
 0.11
chr7_130602447_130602598 0.22 ENSG00000226380
 .
 40224
 0.17
chr10_95172691_95172842 0.22 MYOF
 myoferlin
 69185
 0.1
chr20_37360527_37360678 0.22 SLC32A1
 solute carrier family 32 (GABA vesicular transporter), member 1
 7497
 0.17
chr4_77905705_77905940 0.22 SEPT11
 septin 11
 355
 0.91
chr3_169755608_169756727 0.22 GPR160
 G protein-coupled receptor 160
 241
 0.91
chr7_98970111_98970529 0.22 ARPC1B
 actin related protein 2/3 complex, subunit 1B, 41kDa
 1552
 0.28
chr6_105388737_105389249 0.22 LIN28B
 lin-28 homolog B (C. elegans)
 15930
 0.23
chr4_38611399_38611550 0.22 RP11-617D20.1
14722
 0.22
chr20_18296318_18296469 0.22 RP4-568F9.3
638
 0.6
chr1_84831627_84831778 0.22 SAMD13
 sterile alpha motif domain containing 13
 21183
 0.19
chr12_53264228_53264379 0.22 KRT78
 keratin 78
 21427
 0.12
chr10_18446622_18446802 0.22 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
 16603
 0.26
chr3_15332172_15332523 0.22 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 14795
 0.14
chr5_142185385_142185536 0.22 ARHGAP26
 Rho GTPase activating protein 26
 33178
 0.2
chr2_145765254_145765507 0.22 ENSG00000253036
 .
 327258
 0.01
chr13_99645097_99645248 0.22 DOCK9
 dedicator of cytokinesis 9
 14834
 0.22
chr4_10007868_10008019 0.22 RP11-448G15.1
163
 0.95
chr4_72125821_72125972 0.22 SLC4A4
 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
 72852
 0.13
chr2_125926045_125926196 0.22 ENSG00000201853
 .
 39711
 0.23
chr8_135433860_135434011 0.21 ZFAT
 zinc finger and AT hook domain containing
 88490
 0.1
chr15_33121037_33121231 0.21 FMN1
 formin 1
 59321
 0.11
chr17_77767116_77767731 0.21 CBX8
 chromobox homolog 8
 3492
 0.16
chr5_443562_444067 0.21 EXOC3
 exocyst complex component 3
 431
 0.52
chr2_151339584_151339865 0.21 RND3
 Rho family GTPase 3
 2172
 0.49
chr1_1676260_1677404 0.21 SLC35E2
 solute carrier family 35, member E2
 526
 0.68
chr10_7306332_7306626 0.21 SFMBT2
 Scm-like with four mbt domains 2
 144228
 0.05
chr8_107965641_107965792 0.21 ABRA
 actin-binding Rho activating protein
 183243
 0.03
chr1_91189429_91189597 0.21 BARHL2
 BarH-like homeobox 2
 6719
 0.31
chr1_201228727_201229116 0.21 PKP1
 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
 23659
 0.15
chrX_69674453_69675874 0.21 DLG3
 discs, large homolog 3 (Drosophila)
 217
 0.75
chr1_65430726_65432146 0.21 JAK1
 Janus kinase 1
 751
 0.73
chr5_139927168_139928105 0.21 EIF4EBP3
 eukaryotic translation initiation factor 4E binding protein 3
 385
 0.69
chr6_160015485_160015820 0.21 SOD2
 superoxide dismutase 2, mitochondrial
 98608
 0.07
chr19_13906290_13907522 0.21 ZSWIM4
 zinc finger, SWIM-type containing 4
 632
 0.39
chr2_208095383_208095534 0.21 AC007879.5
23518
 0.19
chr9_78796062_78796213 0.21 PCSK5
 proprotein convertase subtilisin/kexin type 5
 7418
 0.32
chr1_173854808_173854959 0.21 ZBTB37
 zinc finger and BTB domain containing 37
 16789
 0.1
chr4_54174706_54174935 0.21 ENSG00000207385
 .
 43086
 0.16
chr19_56166514_56167932 0.21 U2AF2
 U2 small nuclear RNA auxiliary factor 2
 792
 0.34
chr7_41223414_41223565 0.21 AC005160.3
408332
 0.01
chr16_4710556_4710707 0.21 MGRN1
 mahogunin ring finger 1, E3 ubiquitin protein ligase
 10230
 0.11
chr2_242495139_242495290 0.21 BOK
 BCL2-related ovarian killer
 2922
 0.17
chr10_99608959_99609709 0.21 GOLGA7B
 golgin A7 family, member B
 662
 0.7
chr5_158689547_158690875 0.20 UBLCP1
 ubiquitin-like domain containing CTD phosphatase 1
 122
 0.96
chr2_102359188_102359339 0.20 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 44271
 0.19
chr2_176931780_176932252 0.20 EVX2
 even-skipped homeobox 2
 16625
 0.1
chr21_35348616_35348984 0.20 LINC00649
 long intergenic non-protein coding RNA 649
 6980
 0.21
chr16_75046673_75046884 0.20 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 10583
 0.2
chr10_63642613_63642764 0.20 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 18371
 0.24
chr8_49835583_49835808 0.20 SNAI2
 snail family zinc finger 2
 1396
 0.59
chr9_117868310_117868461 0.20 TNC
 tenascin C
 6651
 0.27
chr2_201171688_201172904 0.20 SPATS2L
 spermatogenesis associated, serine-rich 2-like
 701
 0.76
chr6_85472920_85473300 0.20 TBX18
 T-box 18
 37
 0.99

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ELF3_EHF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.1 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.1 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.2 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.2 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.1 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.2 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:2000189 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.2 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0060856 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009) establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.2 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0003179 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0048342 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.2 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0072077 renal vesicle morphogenesis(GO:0072077)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.2 GO:0046040 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.2 GO:0007143 female meiotic division(GO:0007143)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0030432 peristalsis(GO:0030432)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.3 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.0 GO:0001660 fever generation(GO:0001660)
0.0 0.0 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.2 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0 0.1 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.0 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0060685 regulation of prostatic bud formation(GO:0060685)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.0 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0 0.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848) smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:1902692 regulation of neuroblast proliferation(GO:1902692)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.0 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0 0.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:0032276 regulation of gonadotropin secretion(GO:0032276)
0.0 0.0 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.0 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.0 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0031128 organ induction(GO:0001759) developmental induction(GO:0031128)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.0 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.2 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0061515 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.0 0.0 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.0 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.0 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.2 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 1.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing