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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EMX1

Z-value: 0.77

Motif logo

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Transcription factors associated with EMX1

Gene Symbol Gene ID Gene Info
ENSG00000135638.9 EMX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
EMX1chr2_73207135_73207286560930.121757-0.393.0e-01Click!
EMX1chr2_73147833_7314798425980.3209360.333.9e-01Click!
EMX1chr2_73151228_731513791860.958240-0.314.2e-01Click!
EMX1chr2_73145753_731459995660.7988840.255.2e-01Click!
EMX1chr2_73145316_731457332140.9494370.196.2e-01Click!

Activity of the EMX1 motif across conditions

Conditions sorted by the z-value of the EMX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr21_17909068_17909746 0.65 ENSG00000207638
.
2002
0.33
chr11_65324098_65324348 0.48 LTBP3
latent transforming growth factor beta binding protein 3
1013
0.31
chr13_38172411_38172686 0.47 POSTN
periostin, osteoblast specific factor
315
0.95
chrX_25020829_25021251 0.46 ARX
aristaless related homeobox
13025
0.26
chr3_98619475_98619750 0.41 DCBLD2
discoidin, CUB and LCCL domain containing 2
403
0.8
chr10_123458202_123458353 0.35 RP11-78A18.2

37541
0.2
chr15_96878465_96878729 0.34 ENSG00000222651
.
2107
0.24
chr15_96817385_96817602 0.33 NR2F2-AS1
NR2F2 antisense RNA 1
1732
0.37
chr18_53089837_53090372 0.33 TCF4
transcription factor 4
361
0.89
chr15_71054590_71054766 0.31 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
1091
0.55
chr17_37774592_37774840 0.31 PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
8277
0.12
chr20_59830411_59830643 0.31 CDH4
cadherin 4, type 1, R-cadherin (retinal)
3045
0.42
chr13_34071233_34071384 0.30 STARD13
StAR-related lipid transfer (START) domain containing 13
146541
0.04
chr5_2750019_2750705 0.29 IRX2
iroquois homeobox 2
1407
0.43
chr10_63809082_63810748 0.29 ARID5B
AT rich interactive domain 5B (MRF1-like)
945
0.69
chr3_25471806_25472309 0.29 RARB
retinoic acid receptor, beta
2255
0.41
chr6_3750219_3750380 0.28 RP11-420L9.5

1046
0.5
chr4_109532705_109532935 0.28 RPL34
ribosomal protein L34
8902
0.2
chr21_17442999_17443232 0.28 ENSG00000252273
.
35286
0.24
chr3_112356169_112356393 0.28 CCDC80
coiled-coil domain containing 80
663
0.77
chr11_42259823_42259974 0.28 LRRC4C
leucine rich repeat containing 4C
778575
0.0
chr13_107160462_107160937 0.28 EFNB2
ephrin-B2
26763
0.24
chr4_186696107_186696537 0.27 SORBS2
sorbin and SH3 domain containing 2
108
0.98
chr11_131780111_131780399 0.27 NTM
neurotrimin
642
0.77
chr8_87188438_87188625 0.27 CTD-3118D11.3

4116
0.24
chr7_32109713_32110083 0.26 PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
563
0.87
chr4_95917210_95917447 0.26 BMPR1B
bone morphogenetic protein receptor, type IB
55
0.99
chr4_169553357_169553551 0.26 PALLD
palladin, cytoskeletal associated protein
686
0.73
chr13_109808054_109808728 0.25 MYO16-AS1
MYO16 antisense RNA 1
45440
0.18
chr6_116833589_116833880 0.25 TRAPPC3L
trafficking protein particle complex 3-like
228
0.83
chr10_33622034_33622426 0.25 NRP1
neuropilin 1
1080
0.63
chr17_831046_831241 0.25 RP11-676J12.7
Uncharacterized protein
18271
0.15
chr6_136990410_136990561 0.25 MAP3K5
mitogen-activated protein kinase kinase kinase 5
12886
0.19
chr2_54668695_54668846 0.25 SPTBN1
spectrin, beta, non-erythrocytic 1
14652
0.24
chr5_134370433_134370584 0.25 PITX1
paired-like homeodomain 1
5
0.97
chr11_86514261_86514754 0.24 PRSS23
protease, serine, 23
2922
0.38
chr7_77038696_77038897 0.24 GSAP
gamma-secretase activating protein
6388
0.24
chr9_21555895_21556299 0.24 MIR31HG
MIR31 host gene (non-protein coding)
3571
0.22
chr18_67910518_67910950 0.24 RTTN
rotatin
37553
0.17
chr10_33425652_33425891 0.24 ENSG00000263576
.
38207
0.16
chr2_157657104_157657488 0.24 ENSG00000263848
.
214473
0.02
chr13_76042243_76042399 0.23 TBC1D4
TBC1 domain family, member 4
13929
0.23
chr8_77592906_77593199 0.23 ZFHX4
zinc finger homeobox 4
402
0.86
chr11_126989829_126989980 0.23 KIRREL3-AS3
KIRREL3 antisense RNA 3
117099
0.06
chr1_16483683_16483834 0.23 EPHA2
EPH receptor A2
1176
0.29
chr11_6948113_6948733 0.23 ZNF215
zinc finger protein 215
670
0.62
chr3_159483781_159484285 0.23 IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
1141
0.44
chr17_66031093_66031463 0.23 KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
357
0.87
chr10_17707589_17707769 0.23 ENSG00000251959
.
13508
0.15
chr4_55093377_55093528 0.23 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
1812
0.46
chr17_60954301_60954474 0.23 ENSG00000207552
.
67189
0.11
chr3_13080776_13080942 0.23 IQSEC1
IQ motif and Sec7 domain 1
33758
0.22
chr8_27131821_27132033 0.23 STMN4
stathmin-like 4
15990
0.18
chr9_22008020_22008450 0.22 CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
717
0.61
chr15_86037970_86038121 0.22 AKAP13
A kinase (PRKA) anchor protein 13
49226
0.13
chr10_29010683_29010909 0.22 ENSG00000201001
.
38936
0.14
chr6_117804579_117805184 0.22 DCBLD1
discoidin, CUB and LCCL domain containing 1
1056
0.49
chrX_86773476_86773748 0.22 KLHL4
kelch-like family member 4
795
0.74
chr6_108685387_108685624 0.22 ENSG00000200799
.
27772
0.18
chr2_238638558_238638814 0.22 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
37704
0.16
chr3_150131821_150132388 0.22 TSC22D2
TSC22 domain family, member 2
3308
0.35
chr3_79067433_79067887 0.22 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
34
0.99
chr15_67803077_67803228 0.22 C15orf61
chromosome 15 open reading frame 61
10254
0.21
chr1_197730742_197731002 0.22 RP11-448G4.4

4423
0.25
chr13_110957949_110958238 0.21 COL4A2
collagen, type IV, alpha 2
66
0.97
chr15_69367071_69367289 0.21 RP11-809H16.4

31275
0.17
chr4_160426427_160426682 0.21 ENSG00000251979
.
1626
0.54
chr10_30347491_30347726 0.21 KIAA1462
KIAA1462
845
0.76
chr9_135644688_135645326 0.21 RP11-295G24.5

592
0.77
chr1_159111648_159111897 0.21 AIM2
absent in melanoma 2
1474
0.37
chr1_88150357_88150552 0.21 ENSG00000199318
.
231398
0.02
chr9_75767359_75768171 0.21 ANXA1
annexin A1
947
0.7
chr13_33161756_33162354 0.21 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
1491
0.5
chr3_156893095_156894129 0.21 ENSG00000243176
.
476
0.72
chr9_43685829_43685980 0.21 CNTNAP3B
contactin associated protein-like 3B
994
0.67
chr9_41432727_41433091 0.21 SPATA31A5
SPATA31 subfamily A, member 5
67770
0.13
chr14_103522247_103522550 0.21 CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
1401
0.41
chr1_233723927_233724223 0.20 KCNK1
potassium channel, subfamily K, member 1
25675
0.21
chr3_16024121_16024347 0.20 ENSG00000207815
.
108956
0.06
chr15_96868192_96868343 0.20 NR2F2
nuclear receptor subfamily 2, group F, member 2
900
0.49
chr9_136889856_136890052 0.20 LINC00094
long intergenic non-protein coding RNA 94
607
0.71
chr15_71006306_71006466 0.20 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
10772
0.26
chr8_77589944_77590318 0.20 ZFHX4
zinc finger homeobox 4
3323
0.29
chr12_56917781_56918152 0.20 RBMS2
RNA binding motif, single stranded interacting protein 2
2183
0.23
chr11_20179312_20179463 0.20 DBX1
developing brain homeobox 1
2483
0.35
chr4_119755136_119755442 0.20 SEC24D
SEC24 family member D
2004
0.43
chr17_35289223_35289419 0.20 RP11-445F12.1

4600
0.15
chr13_106899243_106899412 0.20 ENSG00000222682
.
91488
0.09
chr4_183475412_183475644 0.20 ENSG00000252343
.
5716
0.29
chrX_6697105_6697256 0.20 VCX3A
variable charge, X-linked 3A
244021
0.02
chr9_39287322_39287607 0.20 CNTNAP3
contactin associated protein-like 3
628
0.81
chr3_56501298_56501701 0.20 ERC2
ELKS/RAB6-interacting/CAST family member 2
892
0.73
chr3_105657205_105657471 0.20 CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
68942
0.15
chr12_116008040_116008436 0.20 ENSG00000240205
.
147292
0.05
chr1_78472118_78472672 0.20 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
1857
0.26
chr9_3794141_3794308 0.20 RP11-252M18.3

81360
0.1
chr4_66533756_66533907 0.20 EPHA5
EPH receptor A5
1822
0.52
chr7_116312981_116313724 0.19 MET
met proto-oncogene
893
0.68
chr5_124082726_124083211 0.19 ZNF608
zinc finger protein 608
648
0.62
chr10_69867817_69868100 0.19 MYPN
myopalladin
1036
0.55
chr8_48648492_48649280 0.19 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
2762
0.26
chr2_43746685_43747132 0.19 THADA
thyroid adenoma associated
50746
0.15
chr4_66536403_66536611 0.19 EPHA5
EPH receptor A5
294
0.95
chr3_69129681_69129838 0.19 UBA3
ubiquitin-like modifier activating enzyme 3
200
0.92
chr5_172753672_172753903 0.19 STC2
stanniocalcin 2
13
0.98
chr2_27861313_27861464 0.19 ENSG00000206731
.
3648
0.13
chr11_86406998_86407150 0.19 ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
23396
0.25
chr18_67822225_67822376 0.19 RTTN
rotatin
50662
0.17
chr1_78471558_78472034 0.19 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
1258
0.34
chr3_171592483_171592715 0.19 TMEM212-IT1
TMEM212 intronic transcript 1 (non-protein coding)
19627
0.19
chr3_177954621_177954974 0.19 KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
35923
0.23
chr5_118653769_118653920 0.19 ENSG00000243333
.
11518
0.19
chr9_21973547_21973827 0.19 CDKN2A
cyclin-dependent kinase inhibitor 2A
1170
0.41
chr7_28726429_28726958 0.19 CREB5
cAMP responsive element binding protein 5
1095
0.68
chr2_202987834_202988283 0.19 AC079354.3

6277
0.17
chr16_50531355_50531506 0.19 ENSG00000252077
.
711
0.7
chr15_88020923_88021173 0.19 ENSG00000207150
.
3528
0.4
chr1_225610206_225610357 0.19 LBR
lamin B receptor
5318
0.2
chr18_30310087_30311054 0.19 AC012123.1
Uncharacterized protein
39188
0.17
chr16_86599945_86600151 0.19 FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
809
0.48
chr11_104838069_104839428 0.19 CASP4
caspase 4, apoptosis-related cysteine peptidase
1345
0.45
chr12_76816173_76817087 0.18 OSBPL8
oxysterol binding protein-like 8
416
0.9
chr12_14369272_14369482 0.18 ENSG00000266749
.
3349
0.3
chr12_10821249_10821400 0.18 STYK1
serine/threonine/tyrosine kinase 1
4933
0.2
chr7_98029134_98029377 0.18 BAIAP2L1
BAI1-associated protein 2-like 1
1125
0.59
chr21_35898258_35899173 0.18 RCAN1
regulator of calcineurin 1
407
0.86
chr17_13424489_13424747 0.18 ENSG00000266115
.
20973
0.19
chr12_50615145_50616830 0.18 LIMA1
LIM domain and actin binding 1
144
0.93
chr6_151188569_151188720 0.18 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
951
0.67
chr1_109740352_109740715 0.18 ENSG00000238310
.
9937
0.15
chr5_87968314_87968590 0.18 CTC-467M3.1

3584
0.24
chr12_46757806_46758524 0.18 SLC38A2
solute carrier family 38, member 2
925
0.64
chr10_116474996_116475239 0.18 ABLIM1
actin binding LIM protein 1
30703
0.21
chr4_186853985_186854481 0.18 ENSG00000239034
.
13004
0.21
chr12_76271082_76271233 0.18 ENSG00000243420
.
80753
0.1
chr5_142600508_142600686 0.18 ARHGAP26
Rho GTPase activating protein 26
13832
0.24
chrX_117490564_117490715 0.18 WDR44
WD repeat domain 44
10533
0.21
chr17_10601145_10601947 0.18 ADPRM
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
635
0.41
chr5_142556532_142556683 0.18 ARHGAP26-IT1
ARHGAP26 intronic transcript 1 (non-protein coding)
15458
0.24
chr15_60388257_60388408 0.18 FOXB1
forkhead box B1
91911
0.09
chr1_112283056_112283209 0.18 FAM212B-AS1
FAM212B antisense RNA 1
657
0.55
chr7_142981719_142981870 0.18 TMEM139
transmembrane protein 139
249
0.82
chr13_24275550_24275701 0.18 AL139080.1
Uncharacterized protein
46618
0.16
chr6_111136518_111136697 0.18 CDK19
cyclin-dependent kinase 19
88
0.97
chr12_72724242_72724393 0.18 ENSG00000236333
.
55630
0.15
chr8_77599205_77599356 0.18 ZFHX4
zinc finger homeobox 4
3264
0.28
chr10_6763782_6764322 0.18 PRKCQ
protein kinase C, theta
141789
0.05
chr4_105315936_105316087 0.18 ENSG00000272082
.
96022
0.08
chr5_77822199_77822489 0.18 LHFPL2
lipoma HMGIC fusion partner-like 2
22630
0.27
chr17_64476407_64476558 0.18 RP11-4F22.2

63510
0.12
chr15_31631556_31631837 0.17 KLF13
Kruppel-like factor 13
440
0.9
chr8_12986347_12986498 0.17 DLC1
deleted in liver cancer 1
4561
0.27
chr14_25580559_25580710 0.17 STXBP6
syntaxin binding protein 6 (amisyn)
61131
0.16
chr6_116834038_116834189 0.17 TRAPPC3L
trafficking protein particle complex 3-like
607
0.55
chr5_102897969_102898137 0.17 NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
437
0.91
chr6_165341513_165341675 0.17 C6orf118
chromosome 6 open reading frame 118
380748
0.01
chr17_66700653_66700804 0.17 ENSG00000263690
.
61972
0.13
chr3_81474618_81474769 0.17 ENSG00000222389
.
83934
0.11
chr1_244175859_244176064 0.17 ZBTB18
zinc finger and BTB domain containing 18
38624
0.17
chr2_213962198_213962349 0.17 IKZF2
IKAROS family zinc finger 2 (Helios)
51080
0.16
chr18_3305605_3305756 0.17 MYL12B
myosin, light chain 12B, regulatory
42726
0.12
chr3_156469026_156469297 0.17 TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
70206
0.1
chr1_68152763_68153190 0.17 GADD45A
growth arrest and DNA-damage-inducible, alpha
2092
0.36
chr10_105609571_105609851 0.17 SH3PXD2A
SH3 and PX domains 2A
5453
0.22
chr12_59509571_59509775 0.17 RP11-150C16.1

195253
0.03
chr11_37129867_37130018 0.17 RAG2
recombination activating gene 2
510156
0.0
chr1_52363576_52363890 0.17 ENSG00000265769
.
2910
0.2
chr19_46088302_46088477 0.17 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
289
0.84
chr12_80794329_80794553 0.17 PTPRQ
protein tyrosine phosphatase, receptor type, Q
5333
0.26
chr4_177191568_177191827 0.17 ASB5
ankyrin repeat and SOCS box containing 5
1324
0.49
chr4_37979283_37980288 0.17 TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
854
0.69
chr17_30954528_30954679 0.17 RP11-220C2.1

154
0.96
chr4_14728626_14728777 0.17 ENSG00000202449
.
36367
0.24
chr11_93865075_93865400 0.17 PANX1
pannexin 1
3142
0.34
chr3_111820458_111820788 0.17 ENSG00000207940
.
11025
0.15
chr4_6887879_6888223 0.17 TBC1D14
TBC1 domain family, member 14
22918
0.18
chr17_12569246_12569498 0.17 MYOCD
myocardin
66
0.98
chr7_32099128_32099768 0.17 PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
11013
0.32
chr4_166361643_166362016 0.17 CPE
carboxypeptidase E
22451
0.23
chr8_107071271_107071422 0.17 ENSG00000251003
.
1325
0.61
chr8_38264174_38264701 0.17 RP11-350N15.6

1823
0.22
chrX_45626469_45627939 0.16 ENSG00000207725
.
20674
0.22
chr8_32440879_32441165 0.16 NRG1
neuregulin 1
22144
0.27
chr2_8135764_8135915 0.16 ENSG00000221255
.
418867
0.01
chr7_30202290_30202472 0.16 AC007036.5

5234
0.19
chr7_20371750_20371946 0.16 CTA-293F17.1

478
0.71
chr13_95752508_95752659 0.16 ENSG00000252335
.
81094
0.1
chr13_110439180_110439367 0.16 IRS2
insulin receptor substrate 2
358
0.92
chr7_134465735_134465936 0.16 CALD1
caldesmon 1
1406
0.57
chr10_116584415_116584656 0.16 FAM160B1
family with sequence similarity 160, member B1
3006
0.37
chr18_74781332_74781483 0.16 MBP
myelin basic protein
35810
0.21
chr3_153644904_153645055 0.16 ENSG00000238755
.
52996
0.15
chr1_28833432_28833903 0.16 SNHG3
small nucleolar RNA host gene 3 (non-protein coding)
211
0.82
chr9_135038389_135038692 0.16 NTNG2
netrin G2
1206
0.56
chr7_80513051_80513202 0.16 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
35373
0.24
chr14_29859562_29859789 0.16 ENSG00000257522
.
11813
0.29
chr11_12699031_12699547 0.16 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
2239
0.43
chr1_162603392_162603656 0.16 DDR2
discoidin domain receptor tyrosine kinase 2
1264
0.48
chr12_49661445_49661747 0.16 TUBA1C
tubulin, alpha 1c
2732
0.15
chr2_64244915_64245982 0.16 VPS54
vacuolar protein sorting 54 homolog (S. cerevisiae)
758
0.76

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of EMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.3 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.1 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1 0.2 GO:0072007 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.1 0.3 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.2 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0003179 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.2 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0060057 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0002669 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.2 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0036294 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.4 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.0 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0009261 ribonucleotide catabolic process(GO:0009261)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:0031529 ruffle organization(GO:0031529)
0.0 0.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0060751 branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.0 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0060487 lung epithelial cell differentiation(GO:0060487)
0.0 0.0 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0010870 positive regulation of receptor biosynthetic process(GO:0010870)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:1901863 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0035246 peptidyl-arginine methylation(GO:0018216) peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.0 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0 0.0 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.0 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.0 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.0 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.0 GO:0003254 regulation of membrane depolarization(GO:0003254) regulation of mitochondrial depolarization(GO:0051900)
0.0 0.3 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.0 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0032288 myelin assembly(GO:0032288)
0.0 0.0 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0047496 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.0 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.4 GO:0030522 intracellular receptor signaling pathway(GO:0030522)
0.0 0.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.0 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.0 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.9 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.8 GO:0030016 myofibril(GO:0030016)
0.0 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0044217 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.5 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.0 GO:0032356 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.0 0.1 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.0 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway