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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EMX2

Z-value: 1.89

Motif logo

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Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
ENSG00000170370.10 EMX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
EMX2chr10_119302142_1193023462650.637902-0.432.4e-01Click!
EMX2chr10_119303143_1193033337290.610624-0.108.0e-01Click!
EMX2chr10_119301926_119302136760.6609110.019.8e-01Click!

Activity of the EMX2 motif across conditions

Conditions sorted by the z-value of the EMX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_123682878_123683088 0.86 TRAF1
TNF receptor-associated factor 1
6133
0.22
chr14_22974481_22974956 0.85 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
18547
0.09
chr4_84035334_84035716 0.81 PLAC8
placenta-specific 8
343
0.91
chr1_39681454_39681741 0.75 RP11-416A14.1

9413
0.17
chr20_21080465_21081932 0.74 ENSG00000199509
.
38517
0.18
chr12_47611625_47611801 0.72 PCED1B
PC-esterase domain containing 1B
1332
0.49
chr4_153431926_153432077 0.71 ENSG00000264678
.
21433
0.17
chr13_31309966_31310295 0.71 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
485
0.88
chr14_91882143_91882344 0.70 CCDC88C
coiled-coil domain containing 88C
1447
0.49
chr2_204573850_204574006 0.68 CD28
CD28 molecule
2512
0.36
chrX_21992254_21992490 0.67 SMS
spermine synthase
33209
0.17
chr14_99726709_99727240 0.67 AL109767.1

2311
0.33
chr1_198608588_198608957 0.67 PTPRC
protein tyrosine phosphatase, receptor type, C
480
0.86
chr11_122940168_122940622 0.65 HSPA8
heat shock 70kDa protein 8
6457
0.15
chr4_36245078_36245884 0.64 ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
80
0.74
chr2_196281841_196281992 0.64 ENSG00000202206
.
96844
0.09
chr17_37932472_37932886 0.62 IKZF3
IKAROS family zinc finger 3 (Aiolos)
1799
0.27
chr2_158295494_158296053 0.60 CYTIP
cytohesin 1 interacting protein
153
0.96
chr3_111261315_111261845 0.59 CD96
CD96 molecule
583
0.82
chr4_84032848_84033051 0.58 PLAC8
placenta-specific 8
1953
0.4
chr12_54891959_54892179 0.58 NCKAP1L
NCK-associated protein 1-like
499
0.73
chr22_40324201_40324352 0.58 GRAP2
GRB2-related adaptor protein 2
1635
0.36
chr5_169720489_169720914 0.58 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
4530
0.26
chrX_150695771_150695922 0.58 PASD1
PAS domain containing 1
36248
0.2
chr14_22968352_22968523 0.58 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
12266
0.1
chr6_71125805_71125956 0.57 RP11-462G2.2

2227
0.31
chr17_38018344_38018495 0.57 IKZF3
IKAROS family zinc finger 3 (Aiolos)
1960
0.26
chr14_88471433_88472132 0.57 GPR65
G protein-coupled receptor 65
314
0.88
chr2_113932280_113932569 0.56 AC016683.5

490
0.59
chr13_40532306_40532606 0.56 ENSG00000212553
.
101092
0.08
chr5_156610422_156610951 0.56 ITK
IL2-inducible T-cell kinase
2849
0.18
chr20_35575234_35575857 0.56 SAMHD1
SAM domain and HD domain 1
4566
0.25
chr3_132628264_132628415 0.56 TMEM108
transmembrane protein 108
128896
0.05
chr13_46755198_46755455 0.56 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
1133
0.45
chr12_9912315_9912520 0.55 CD69
CD69 molecule
1080
0.47
chr11_104904746_104905919 0.55 CASP1
caspase 1, apoptosis-related cysteine peptidase
508
0.77
chr3_30650793_30651257 0.55 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
2932
0.39
chr11_104941725_104942216 0.54 CARD16
caspase recruitment domain family, member 16
25867
0.14
chr1_151130261_151130413 0.54 SCNM1
sodium channel modifier 1
1197
0.22
chr14_22947593_22947744 0.53 TRAJ60
T cell receptor alpha joining 60 (pseudogene)
2372
0.15
chr2_143887583_143887860 0.52 ARHGAP15
Rho GTPase activating protein 15
838
0.72
chr15_60874237_60874501 0.52 RORA
RAR-related orphan receptor A
10371
0.22
chr6_128221212_128221624 0.52 THEMIS
thymocyte selection associated
685
0.81
chr14_22958789_22958996 0.51 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
2721
0.15
chr3_18477156_18477307 0.50 SATB1
SATB homeobox 1
486
0.83
chr2_204801338_204802214 0.50 ICOS
inducible T-cell co-stimulator
273
0.95
chr1_158903283_158903483 0.50 PYHIN1
pyrin and HIN domain family, member 1
2025
0.36
chr2_201238626_201239302 0.50 ENSG00000201649
.
1066
0.5
chr11_104971227_104972126 0.50 CASP1
caspase 1, apoptosis-related cysteine peptidase
482
0.32
chr5_156608669_156608858 0.49 ITK
IL2-inducible T-cell kinase
926
0.47
chr6_152505006_152505157 0.49 SYNE1
spectrin repeat containing, nuclear envelope 1
15582
0.29
chr2_204572133_204572358 0.48 CD28
CD28 molecule
829
0.71
chr10_6102754_6102905 0.48 IL2RA
interleukin 2 receptor, alpha
1424
0.36
chrX_78403845_78404040 0.48 GPR174
G protein-coupled receptor 174
22527
0.28
chr3_43331814_43332301 0.47 SNRK
SNF related kinase
3979
0.23
chr16_86638626_86639076 0.46 FOXL1
forkhead box L1
26736
0.16
chr3_151962421_151962590 0.46 MBNL1
muscleblind-like splicing regulator 1
23324
0.2
chr6_143263290_143263441 0.46 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
2973
0.34
chr8_76807046_76807197 0.45 ENSG00000238595
.
1982
0.49
chrX_135730500_135730717 0.45 CD40LG
CD40 ligand
222
0.93
chr11_121298288_121298439 0.45 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
24549
0.21
chr1_100887767_100887999 0.45 ENSG00000216067
.
43552
0.14
chr1_112013416_112013602 0.45 C1orf162
chromosome 1 open reading frame 162
2905
0.14
chr5_165288349_165288500 0.45 ENSG00000252794
.
251978
0.02
chr10_17548651_17548924 0.45 ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
52458
0.13
chr1_169678923_169679233 0.44 SELL
selectin L
1761
0.36
chr7_106507057_106507208 0.44 PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
1208
0.59
chr15_86235334_86235485 0.44 RP11-815J21.1

8931
0.12
chr7_138790255_138790726 0.44 ZC3HAV1
zinc finger CCCH-type, antiviral 1
3610
0.26
chr14_74724486_74725063 0.44 VSX2
visual system homeobox 2
18599
0.14
chr5_150593261_150593549 0.44 GM2A
GM2 ganglioside activator
1694
0.36
chr14_102278905_102279056 0.44 CTD-2017C7.2

2322
0.22
chr18_60825953_60826104 0.44 RP11-299P2.1

7475
0.24
chr6_108145054_108145346 0.44 SCML4
sex comb on midleg-like 4 (Drosophila)
316
0.93
chr14_22970384_22970535 0.43 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
14288
0.1
chr13_84126063_84126363 0.43 ENSG00000222791
.
253911
0.02
chr6_98415844_98415995 0.43 ENSG00000238367
.
56488
0.18
chr5_77901409_77901560 0.43 LHFPL2
lipoma HMGIC fusion partner-like 2
43164
0.21
chr2_24114630_24115019 0.43 ATAD2B
ATPase family, AAA domain containing 2B
24067
0.18
chr14_100689805_100690076 0.43 YY1
YY1 transcription factor
14695
0.11
chr12_25206187_25206540 0.43 LRMP
lymphoid-restricted membrane protein
689
0.71
chrX_11779384_11779693 0.43 MSL3
male-specific lethal 3 homolog (Drosophila)
1791
0.5
chr13_41591572_41591774 0.43 ELF1
E74-like factor 1 (ets domain transcription factor)
1777
0.37
chr12_54132160_54132404 0.42 CALCOCO1
calcium binding and coiled-coil domain 1
10753
0.17
chr6_37410160_37410312 0.42 CMTR1
cap methyltransferase 1
9240
0.22
chr1_111212990_111213454 0.42 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
4433
0.21
chr12_49311955_49312141 0.42 FKBP11
FK506 binding protein 11, 19 kDa
6702
0.08
chr9_117690832_117691467 0.42 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
1548
0.52
chr5_98362961_98363596 0.42 ENSG00000200351
.
90827
0.09
chr1_149579136_149579307 0.41 RP11-353N4.6

2608
0.2
chr3_141249287_141249763 0.41 RASA2-IT1
RASA2 intronic transcript 1 (non-protein coding)
5550
0.26
chr5_156616823_156617066 0.41 ITK
IL2-inducible T-cell kinase
9107
0.13
chr21_35306376_35306527 0.41 LINC00649
long intergenic non-protein coding RNA 649
2933
0.21
chr7_142430441_142430617 0.40 PRSS1
protease, serine, 1 (trypsin 1)
26790
0.17
chr3_52309275_52309582 0.40 WDR82
WD repeat domain 82
2909
0.12
chr8_8727017_8727210 0.40 MFHAS1
malignant fibrous histiocytoma amplified sequence 1
24042
0.18
chr1_24862040_24862255 0.40 ENSG00000266551
.
5943
0.18
chr1_198620819_198621442 0.40 PTPRC
protein tyrosine phosphatase, receptor type, C
12838
0.23
chr12_46063121_46063382 0.40 ARID2
AT rich interactive domain 2 (ARID, RFX-like)
60197
0.15
chr5_176037885_176038043 0.39 GPRIN1
G protein regulated inducer of neurite outgrowth 1
830
0.48
chr15_31622749_31622975 0.39 KLF13
Kruppel-like factor 13
3804
0.36
chr1_198615140_198615291 0.39 PTPRC
protein tyrosine phosphatase, receptor type, C
6923
0.25
chr7_146801323_146801474 0.39 AC006004.1

6697
0.34
chr2_99278961_99279112 0.38 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
900
0.64
chr11_117151480_117151734 0.38 BACE1
beta-site APP-cleaving enzyme 1
14594
0.13
chr4_90226799_90226950 0.38 GPRIN3
GPRIN family member 3
2287
0.45
chr12_10019991_10020525 0.38 RP11-290C10.1

632
0.61
chr5_118606885_118607036 0.38 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
2511
0.28
chr22_31685289_31685466 0.38 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
3004
0.15
chr2_143887292_143887566 0.38 ARHGAP15
Rho GTPase activating protein 15
546
0.84
chr11_88068800_88069370 0.38 CTSC
cathepsin C
1816
0.49
chr13_41557403_41557660 0.38 ELF1
E74-like factor 1 (ets domain transcription factor)
1113
0.53
chr7_43626899_43627416 0.37 STK17A
serine/threonine kinase 17a
4493
0.21
chr2_87830138_87830289 0.37 RP11-1399P15.1

52660
0.16
chr13_99966823_99967055 0.37 GPR183
G protein-coupled receptor 183
7280
0.21
chr14_92331424_92331867 0.37 TC2N
tandem C2 domains, nuclear
2228
0.32
chr8_66751055_66751459 0.37 PDE7A
phosphodiesterase 7A
274
0.95
chr14_64974356_64974596 0.37 ZBTB25
zinc finger and BTB domain containing 25
2545
0.17
chr20_49134113_49134959 0.37 PTPN1
protein tyrosine phosphatase, non-receptor type 1
7616
0.17
chr10_47640402_47640757 0.37 ANTXRLP1
anthrax toxin receptor-like pseudogene 1
4212
0.25
chr7_26332124_26332363 0.37 SNX10
sorting nexin 10
431
0.87
chr1_160616915_160617313 0.37 SLAMF1
signaling lymphocytic activation molecule family member 1
29
0.97
chr19_1470719_1471158 0.37 C19orf25
chromosome 19 open reading frame 25
7958
0.07
chr18_60983375_60983526 0.36 RP11-28F1.2

2135
0.26
chr21_32559881_32560032 0.36 TIAM1
T-cell lymphoma invasion and metastasis 1
57417
0.15
chr16_89550769_89551086 0.36 ANKRD11
ankyrin repeat domain 11
5799
0.13
chr5_23012798_23012949 0.36 CDH12
cadherin 12, type 2 (N-cadherin 2)
159142
0.04
chr12_15114929_15115219 0.36 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
412
0.82
chr3_20145563_20145846 0.36 ENSG00000266745
.
33353
0.15
chr7_50350295_50350528 0.36 IKZF1
IKAROS family zinc finger 1 (Ikaros)
2093
0.45
chr5_130603053_130603363 0.36 CDC42SE2
CDC42 small effector 2
3415
0.35
chr13_41555714_41555943 0.36 ELF1
E74-like factor 1 (ets domain transcription factor)
590
0.77
chr2_191929470_191929872 0.36 ENSG00000231858
.
43419
0.12
chr6_10522420_10522571 0.36 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
911
0.58
chr3_95425254_95425405 0.36 ENSG00000221477
.
460417
0.01
chr2_109238100_109238434 0.36 LIMS1
LIM and senescent cell antigen-like domains 1
545
0.82
chr14_97924887_97925209 0.36 ENSG00000240730
.
71462
0.14
chr12_55266839_55266990 0.36 MUCL1
mucin-like 1
18593
0.23
chr6_135039787_135039938 0.36 ALDH8A1
aldehyde dehydrogenase 8 family, member A1
210437
0.02
chr3_121373349_121373500 0.35 ENSG00000243544
.
281
0.82
chr1_244488017_244488168 0.35 C1orf100
chromosome 1 open reading frame 100
27845
0.22
chr9_128586563_128586792 0.35 PBX3
pre-B-cell leukemia homeobox 3
40873
0.21
chr6_154568354_154568864 0.35 IPCEF1
interaction protein for cytohesin exchange factors 1
53
0.99
chr6_119398487_119399078 0.35 FAM184A
family with sequence similarity 184, member A
755
0.67
chr5_96294037_96294231 0.35 LNPEP
leucyl/cystinyl aminopeptidase
21
0.98
chr12_111868224_111868441 0.35 SH2B3
SH2B adaptor protein 3
4334
0.21
chr11_104915569_104916017 0.35 CARD16
caspase recruitment domain family, member 16
241
0.92
chrX_135729885_135730036 0.35 CD40LG
CD40 ligand
392
0.84
chr1_113634018_113634169 0.35 LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
18262
0.26
chr3_71351252_71351403 0.35 FOXP1
forkhead box P1
2584
0.35
chr10_46075820_46076565 0.35 MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
13747
0.25
chr11_118134576_118134833 0.35 MPZL2
myelin protein zero-like 2
293
0.86
chr17_28085648_28085799 0.35 RP11-82O19.1

2398
0.25
chr1_200865204_200865355 0.35 C1orf106
chromosome 1 open reading frame 106
1330
0.42
chr6_159465378_159465638 0.35 TAGAP
T-cell activation RhoGTPase activating protein
542
0.78
chr8_66750529_66750680 0.35 PDE7A
phosphodiesterase 7A
379
0.92
chr19_42056193_42056486 0.35 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
453
0.8
chr21_15917916_15918619 0.35 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
395
0.89
chr15_64391220_64391371 0.34 SNX1
sorting nexin 1
3070
0.19
chr1_70750666_70750817 0.34 SRSF11
serine/arginine-rich splicing factor 11
53510
0.1
chr6_130537052_130537203 0.34 SAMD3
sterile alpha motif domain containing 3
48
0.99
chr4_143488982_143489737 0.34 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
7537
0.34
chr19_54873446_54873661 0.34 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
997
0.38
chr12_62652869_62653097 0.34 FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
379
0.79
chr1_206731858_206732141 0.34 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
1506
0.37
chr21_32563083_32563234 0.34 TIAM1
T-cell lymphoma invasion and metastasis 1
60619
0.14
chr15_93431332_93431756 0.34 CHD2
chromodomain helicase DNA binding protein 2
5018
0.2
chr14_102291094_102291439 0.34 CTD-2017C7.1

14602
0.14
chr5_100234956_100235107 0.34 ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
3887
0.35
chrX_39185236_39185387 0.34 ENSG00000207122
.
244773
0.02
chr1_32720364_32720515 0.34 LCK
lymphocyte-specific protein tyrosine kinase
3564
0.11
chr10_8179903_8180054 0.33 GATA3
GATA binding protein 3
83209
0.11
chr2_161994699_161994850 0.33 TANK
TRAF family member-associated NFKB activator
1308
0.52
chr5_67580506_67580669 0.33 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
3609
0.36
chr20_4802726_4803481 0.33 RASSF2
Ras association (RalGDS/AF-6) domain family member 2
1188
0.5
chr3_74315841_74315992 0.33 ENSG00000212585
.
100713
0.09
chr9_117567735_117567886 0.33 TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
596
0.78
chr17_43131298_43131449 0.33 DCAKD
dephospho-CoA kinase domain containing
2386
0.18
chr2_112177530_112177803 0.33 ENSG00000266139
.
98998
0.09
chrX_20996388_20996539 0.33 ENSG00000206716
.
236292
0.02
chr4_36243817_36244102 0.33 ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
1602
0.35
chr22_40322756_40322951 0.33 GRAP2
GRB2-related adaptor protein 2
212
0.93
chr18_22040594_22040766 0.33 HRH4
histamine receptor H4
13
0.97
chr1_198614484_198614635 0.32 PTPRC
protein tyrosine phosphatase, receptor type, C
6267
0.26
chr10_51500864_51501147 0.32 AGAP7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
14678
0.19
chr3_151918471_151919168 0.32 MBNL1
muscleblind-like splicing regulator 1
67010
0.12
chr11_104787850_104788088 0.32 RP11-693N9.2

7327
0.2
chr12_3979327_3979799 0.32 RP11-664D1.1

1337
0.47
chr14_56879487_56879638 0.32 TMEM260
transmembrane protein 260
75510
0.12
chr3_71537739_71537890 0.32 ENSG00000221264
.
53426
0.14
chr14_47010588_47010739 0.32 RPL10L
ribosomal protein L10-like
110365
0.08
chr6_125401116_125401267 0.32 RNF217
ring finger protein 217
31833
0.2
chr12_40077019_40077550 0.32 C12orf40
chromosome 12 open reading frame 40
57299
0.13
chr2_175459196_175459684 0.32 WIPF1
WAS/WASL interacting protein family, member 1
3053
0.24
chr6_16438021_16438172 0.32 ENSG00000265642
.
9342
0.31
chr3_5178219_5178370 0.32 ARL8B
ADP-ribosylation factor-like 8B
14313
0.17
chr7_138788856_138789199 0.32 ZC3HAV1
zinc finger CCCH-type, antiviral 1
5073
0.23
chr2_237446552_237446703 0.32 ACKR3
atypical chemokine receptor 3
29803
0.19
chr8_39259417_39259568 0.32 ENSG00000252176
.
158964
0.04
chr16_302654_303040 0.32 ITFG3
integrin alpha FG-GAP repeat containing 3
1780
0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of EMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.3 0.8 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.2 0.9 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.2 0.6 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.2 0.6 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 0.8 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 0.6 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.2 0.6 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.7 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.4 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1 0.6 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.4 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.0 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.8 GO:0015671 oxygen transport(GO:0015671)
0.1 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.5 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.8 GO:0043383 negative T cell selection(GO:0043383)
0.1 0.4 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.3 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.2 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:0014889 muscle atrophy(GO:0014889)
0.1 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.2 GO:0045588 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.2 GO:0070265 necrotic cell death(GO:0070265)
0.1 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.2 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.2 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.1 0.2 GO:0001821 histamine secretion(GO:0001821)
0.1 0.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.2 GO:0002507 tolerance induction(GO:0002507)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 3.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.6 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 1.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 1.0 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.8 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.0 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.2 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.3 GO:1901222 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.2 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:2000192 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.2 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.0 GO:0002902 regulation of B cell apoptotic process(GO:0002902) negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0042832 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0 0.2 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.7 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.1 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.4 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0060057 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.4 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.6 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0033079 immature T cell proliferation(GO:0033079)
0.0 0.1 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.2 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0051806 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0045581 negative regulation of T cell differentiation(GO:0045581)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0043558 regulation of translation in response to stress(GO:0043555) regulation of translational initiation in response to stress(GO:0043558)
0.0 0.0 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0061046 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.0 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.0 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.0 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.0 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.0 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0036230 granulocyte activation(GO:0036230)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0034227 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0060770 regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0014002 astrocyte development(GO:0014002)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.0 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.7 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.2 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.0 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.0 0.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.0 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.5 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.0 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.0 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0048752 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.0 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441)
0.0 0.0 GO:2000573 positive regulation of telomerase activity(GO:0051973) positive regulation of DNA biosynthetic process(GO:2000573)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.0 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:0060856 establishment of blood-brain barrier(GO:0060856)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.2 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 0.5 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.2 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.1 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.3 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.2 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.0 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 2.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 2.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.2 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.9 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.5 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 2.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.5 GO:0043621 protein self-association(GO:0043621)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.0 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0015440 oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0 0.0 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 2.8 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 0.0 GO:0043495 protein anchor(GO:0043495)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 1.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.1 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID ATM PATHWAY ATM pathway
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 2.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.0 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.0 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN