Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EN1_ESX1_GBX1

Z-value: 0.63

Motif logo

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Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol Gene ID Gene Info
ENSG00000163064.6 EN1
ENSG00000123576.5 ESX1
ENSG00000164900.4 GBX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
EN1chr2_119592973_119593692119220.282041-0.674.9e-02Click!
EN1chr2_119532507_119532686726580.123378-0.674.9e-02Click!
EN1chr2_119587702_119587853174770.269144-0.636.6e-02Click!
EN1chr2_119592778_119592929124010.280898-0.627.7e-02Click!
EN1chr2_119604243_1196044249210.706043-0.561.2e-01Click!
ESX1chrX_103498696_1034988508410.709189-0.862.8e-03Click!
ESX1chrX_103498922_1034991395840.819996-0.844.8e-03Click!
ESX1chrX_103499699_1034998501600.969949-0.665.4e-02Click!
ESX1chrX_103637379_1036375301378400.047066-0.627.2e-02Click!
ESX1chrX_103636911_1036370621373720.047329-0.521.5e-01Click!
GBX1chr7_150864776_1508649522290.877243-0.627.3e-02Click!
GBX1chr7_150864968_1508653985480.636055-0.561.2e-01Click!
GBX1chr7_150864129_1508647332040.892973-0.551.2e-01Click!

Activity of the EN1_ESX1_GBX1 motif across conditions

Conditions sorted by the z-value of the EN1_ESX1_GBX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_139555848_139556033 0.60 TBXAS1
thromboxane A synthase 1 (platelet)
26830
0.22
chr5_77147504_77148481 0.52 TBCA
tubulin folding cofactor A
16612
0.28
chr9_128521797_128522422 0.48 PBX3
pre-B-cell leukemia homeobox 3
11631
0.27
chr17_66289131_66289282 0.44 ARSG
arylsulfatase G
1547
0.31
chr15_75080868_75081404 0.43 ENSG00000264386
.
38
0.76
chrX_30594869_30596024 0.43 CXorf21
chromosome X open reading frame 21
515
0.84
chr15_55547653_55548107 0.42 RAB27A
RAB27A, member RAS oncogene family
6647
0.22
chr11_122940168_122940622 0.41 HSPA8
heat shock 70kDa protein 8
6457
0.15
chr2_88124610_88124761 0.40 RGPD2
RANBP2-like and GRIP domain containing 2
601
0.82
chr6_154568354_154568864 0.40 IPCEF1
interaction protein for cytohesin exchange factors 1
53
0.99
chrY_15016828_15017148 0.39 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
246
0.96
chr11_122597673_122598179 0.38 ENSG00000239079
.
907
0.67
chr11_75603669_75603820 0.38 UVRAG
UV radiation resistance associated
14296
0.14
chr12_10281805_10282201 0.38 CLEC7A
C-type lectin domain family 7, member A
678
0.6
chr12_120105804_120106659 0.38 PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
562
0.74
chr21_39667815_39667966 0.37 KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
589
0.84
chr5_88484775_88484926 0.36 MEF2C-AS1
MEF2C antisense RNA 1
223158
0.02
chr1_66799510_66799957 0.36 PDE4B
phosphodiesterase 4B, cAMP-specific
1861
0.5
chr6_159464766_159465080 0.34 TAGAP
T-cell activation RhoGTPase activating protein
1127
0.51
chr21_15917916_15918619 0.34 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
395
0.89
chr6_2222723_2222882 0.34 GMDS
GDP-mannose 4,6-dehydratase
23124
0.28
chr11_61158553_61158704 0.34 TMEM216
transmembrane protein 216
531
0.65
chr5_70314152_70314347 0.33 NAIP
NLR family, apoptosis inhibitory protein
2288
0.36
chr5_69760327_69760484 0.33 RP11-497H16.7

8870
0.28
chr18_13464907_13465379 0.33 LDLRAD4
low density lipoprotein receptor class A domain containing 4
129
0.93
chr10_70850849_70851349 0.32 SRGN
serglycin
3225
0.25
chr6_27099516_27099912 0.32 HIST1H2BJ
histone cluster 1, H2bj
613
0.5
chr17_18204377_18204528 0.32 TOP3A
topoisomerase (DNA) III alpha
1531
0.27
chr5_68905149_68905341 0.32 RP11-848G14.2

8895
0.19
chr1_51442241_51442392 0.32 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
6700
0.22
chr3_128950544_128950778 0.32 COPG1
coatomer protein complex, subunit gamma 1
17788
0.14
chr17_40400288_40400799 0.31 RP11-358B23.5

20062
0.1
chr8_134086774_134086935 0.31 SLA
Src-like-adaptor
14251
0.23
chr1_169679248_169679951 0.31 SELL
selectin L
1240
0.48
chr14_77873229_77873401 0.30 FKSG61

9426
0.11
chr3_101568772_101569567 0.30 NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
62
0.98
chr6_26198173_26198564 0.30 HIST1H3D
histone cluster 1, H3d
890
0.22
chr7_73509063_73509569 0.30 LIMK1
LIM domain kinase 1
1907
0.33
chrX_9801459_9801610 0.30 ENSG00000206844
.
41207
0.15
chr5_131762557_131762944 0.30 AC116366.5

344
0.83
chr10_7526759_7527322 0.29 ENSG00000207453
.
1731
0.45
chr13_77319930_77320170 0.29 KCTD12
potassium channel tetramerization domain containing 12
140475
0.05
chr1_225610206_225610357 0.29 LBR
lamin B receptor
5318
0.2
chr7_26141262_26141558 0.29 ENSG00000266430
.
41451
0.15
chr2_68594752_68594961 0.29 AC015969.3

2140
0.26
chr1_28267591_28267742 0.29 SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
6045
0.13
chr2_136876136_136876323 0.29 CXCR4
chemokine (C-X-C motif) receptor 4
494
0.87
chr6_36215434_36215585 0.28 PNPLA1
patatin-like phospholipase domain containing 1
4529
0.21
chr5_171560548_171560699 0.28 ENSG00000266671
.
52643
0.12
chrX_78400540_78401325 0.28 GPR174
G protein-coupled receptor 174
25537
0.27
chr12_65013240_65013416 0.28 ENSG00000207546
.
2961
0.17
chr1_239883177_239883989 0.28 CHRM3
cholinergic receptor, muscarinic 3
740
0.59
chr13_46745397_46745548 0.28 ENSG00000240767
.
1589
0.32
chr17_28085648_28085799 0.28 RP11-82O19.1

2398
0.25
chr1_184121923_184122452 0.28 ENSG00000199840
.
18770
0.25
chr12_49627195_49627425 0.28 TUBA1C
tubulin, alpha 1c
5601
0.13
chr20_44634106_44634271 0.28 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
3359
0.16
chr9_120467573_120467933 0.28 TLR4
toll-like receptor 4
1103
0.51
chr17_10601145_10601947 0.28 ADPRM
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
635
0.41
chr12_7985471_7986071 0.27 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
359
0.8
chr14_88471433_88472132 0.27 GPR65
G protein-coupled receptor 65
314
0.88
chr2_158299843_158300108 0.27 CYTIP
cytohesin 1 interacting protein
679
0.68
chr2_64369947_64371114 0.27 AC074289.1

157
0.93
chr8_102802981_102803132 0.27 NCALD
neurocalcin delta
119
0.98
chrX_119737965_119739054 0.27 MCTS1
malignant T cell amplified sequence 1
333
0.88
chr8_12986347_12986498 0.27 DLC1
deleted in liver cancer 1
4561
0.27
chr3_3859837_3859988 0.27 LRRN1
leucine rich repeat neuronal 1
18791
0.29
chr1_158788907_158789058 0.27 MNDA
myeloid cell nuclear differentiation antigen
12125
0.17
chr2_176322753_176322904 0.27 ENSG00000221347
.
127727
0.05
chr18_65188257_65188408 0.27 DSEL
dermatan sulfate epimerase-like
4115
0.29
chr17_75456326_75456913 0.27 SEPT9
septin 9
4171
0.18
chr8_116460480_116460631 0.27 TRPS1
trichorhinophalangeal syndrome I
43893
0.19
chr6_32158116_32158500 0.27 PBX2
pre-B-cell leukemia homeobox 2
345
0.7
chrY_15815919_15816489 0.27 TMSB4Y
thymosin beta 4, Y-linked
757
0.72
chr5_149791368_149791565 0.27 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
829
0.6
chr13_31310422_31310683 0.26 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
907
0.71
chr1_198627689_198627922 0.26 RP11-553K8.5

8385
0.25
chr11_20179312_20179463 0.26 DBX1
developing brain homeobox 1
2483
0.35
chr2_175458036_175458370 0.26 WIPF1
WAS/WASL interacting protein family, member 1
4290
0.21
chr13_31312055_31312206 0.26 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
2485
0.4
chr1_66802476_66802627 0.26 PDE4B
phosphodiesterase 4B, cAMP-specific
4679
0.34
chr17_75955874_75956555 0.26 ENSG00000238898
.
40034
0.14
chr1_209930701_209930998 0.26 TRAF3IP3
TRAF3 interacting protein 3
994
0.46
chr2_192540821_192541028 0.26 NABP1
nucleic acid binding protein 1
1938
0.47
chr7_106507255_106507406 0.25 PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
1406
0.54
chr1_200987607_200987758 0.25 KIF21B
kinesin family member 21B
4854
0.21
chr14_70111468_70111619 0.25 KIAA0247
KIAA0247
33230
0.18
chr1_60036467_60036618 0.25 FGGY
FGGY carbohydrate kinase domain containing
16952
0.29
chr4_185741986_185742137 0.25 ACSL1
acyl-CoA synthetase long-chain family member 1
5127
0.2
chr11_33952138_33952289 0.25 LMO2
LIM domain only 2 (rhombotin-like 1)
38377
0.16
chrY_2804248_2804778 0.25 ZFY
zinc finger protein, Y-linked
967
0.67
chr2_131099802_131100208 0.25 CCDC115
coiled-coil domain containing 115
83
0.67
chr17_29639732_29640055 0.25 EVI2B
ecotropic viral integration site 2B
1209
0.36
chr1_88150357_88150552 0.25 ENSG00000199318
.
231398
0.02
chr3_156893095_156894129 0.24 ENSG00000243176
.
476
0.72
chr4_36245078_36245884 0.24 ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
80
0.74
chr20_43110715_43110866 0.24 TTPAL
tocopherol (alpha) transfer protein-like
6230
0.13
chr3_194821900_194822051 0.24 XXYLT1-AS1
XXYLT1 antisense RNA 1
6658
0.17
chr13_41555714_41555943 0.24 ELF1
E74-like factor 1 (ets domain transcription factor)
590
0.77
chr17_25622078_25622646 0.24 WSB1
WD repeat and SOCS box containing 1
990
0.48
chr9_129252632_129253068 0.24 ENSG00000221768
.
40420
0.14
chr16_50059050_50060305 0.24 CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
246
0.93
chr1_29253817_29254129 0.24 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
12882
0.18
chr13_73613878_73614029 0.24 KLF5
Kruppel-like factor 5 (intestinal)
15161
0.23
chr12_133347795_133347946 0.24 ANKLE2
ankyrin repeat and LEM domain containing 2
9396
0.15
chr2_143887292_143887566 0.24 ARHGAP15
Rho GTPase activating protein 15
546
0.84
chr13_21050204_21050392 0.24 ENSG00000263978
.
42313
0.15
chr7_135656834_135656985 0.24 MTPN
myotrophin
5155
0.19
chr3_174044116_174044267 0.23 NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
114586
0.07
chr17_14652311_14652462 0.23 HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
447986
0.01
chr5_100002492_100002643 0.23 ENSG00000207269
.
66195
0.14
chr7_101361201_101361398 0.23 MYL10
myosin, light chain 10, regulatory
88723
0.08
chr5_126094279_126094440 0.23 ENSG00000252185
.
3250
0.29
chr2_70144352_70144560 0.23 MXD1
MAX dimerization protein 1
2136
0.21
chr9_137029602_137029922 0.23 ENSG00000221676
.
76
0.97
chr2_64500903_64501472 0.23 AC074289.1

45585
0.16
chr14_32672268_32672419 0.23 ENSG00000202337
.
132
0.94
chr7_6114490_6114641 0.23 ENSG00000264605
.
8171
0.11
chr22_40858929_40859404 0.23 MKL1
megakaryoblastic leukemia (translocation) 1
256
0.92
chr14_90187580_90187856 0.23 ENSG00000200312
.
8863
0.23
chr13_105792322_105792542 0.23 DAOA
D-amino acid oxidase activator
326160
0.01
chr5_74615521_74615672 0.23 HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
16558
0.19
chr2_68993241_68993423 0.23 ARHGAP25
Rho GTPase activating protein 25
8601
0.25
chr15_69074948_69075145 0.23 ENSG00000265195
.
19218
0.22
chrX_10066246_10067411 0.23 WWC3
WWC family member 3
35329
0.15
chr4_154448027_154448178 0.23 KIAA0922
KIAA0922
28946
0.22
chr5_79919561_79919712 0.23 CTC-325J23.2

7773
0.17
chr4_147027155_147027306 0.23 ENSG00000216055
.
16206
0.24
chr3_112277196_112277347 0.23 SLC35A5
solute carrier family 35, member A5
3285
0.23
chr1_28975271_28975442 0.23 ENSG00000270103
.
244
0.88
chr17_66700653_66700804 0.23 ENSG00000263690
.
61972
0.13
chr13_31309966_31310295 0.23 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
485
0.88
chr20_48913768_48913919 0.23 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
106467
0.06
chr2_225809390_225809894 0.23 DOCK10
dedicator of cytokinesis 10
2140
0.45
chr15_50627461_50627612 0.22 GABPB1
GA binding protein transcription factor, beta subunit 1
8010
0.14
chr8_82022711_82022967 0.22 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
1464
0.56
chr6_106536140_106536635 0.22 PRDM1
PR domain containing 1, with ZNF domain
932
0.64
chr8_48648492_48649280 0.22 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
2762
0.26
chr1_226251298_226251924 0.22 H3F3A
H3 histone, family 3A
67
0.97
chr21_39645775_39646073 0.22 KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
1495
0.53
chr14_31879526_31879677 0.22 HEATR5A
HEAT repeat containing 5A
7420
0.17
chr3_59696011_59696162 0.22 NPCDR1
nasopharyngeal carcinoma, down-regulated 1
261497
0.02
chrX_40437074_40437225 0.22 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
2997
0.29
chr14_52339978_52340129 0.22 GNG2
guanine nucleotide binding protein (G protein), gamma 2
4257
0.24
chr6_114178016_114178613 0.22 MARCKS
myristoylated alanine-rich protein kinase C substrate
227
0.93
chr7_50348449_50348781 0.22 IKZF1
IKAROS family zinc finger 1 (Ikaros)
297
0.94
chr19_46088302_46088477 0.22 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
289
0.84
chr20_56194431_56194643 0.22 ZBP1
Z-DNA binding protein 1
913
0.65
chr4_2486639_2486842 0.22 RNF4
ring finger protein 4
4798
0.2
chr12_65108828_65108979 0.22 AC025262.1
Mesenchymal stem cell protein DSC96; Uncharacterized protein
18574
0.13
chr1_208047081_208047232 0.22 CD34
CD34 molecule
16681
0.25
chr3_69129681_69129838 0.22 UBA3
ubiquitin-like modifier activating enzyme 3
200
0.92
chr19_54465805_54465956 0.22 CACNG8
calcium channel, voltage-dependent, gamma subunit 8
414
0.72
chr17_81147907_81148162 0.22 METRNL
meteorin, glial cell differentiation regulator-like
96040
0.08
chr8_9005081_9005340 0.22 PPP1R3B
protein phosphatase 1, regulatory subunit 3B
2996
0.21
chr7_150149402_150149565 0.22 GIMAP8
GTPase, IMAP family member 8
1765
0.33
chr1_158983210_158983361 0.22 IFI16
interferon, gamma-inducible protein 16
1186
0.5
chr18_74837172_74837323 0.22 MBP
myelin basic protein
2421
0.42
chr11_61792453_61792604 0.22 AP003733.1
Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
57075
0.08
chr6_42532119_42532973 0.22 UBR2
ubiquitin protein ligase E3 component n-recognin 2
746
0.71
chr5_118606012_118606179 0.22 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
1646
0.37
chr1_150584633_150584820 0.22 ENSG00000253047
.
11591
0.1
chr17_8859778_8859929 0.22 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
9171
0.24
chr3_12228694_12228845 0.22 TIMP4
TIMP metallopeptidase inhibitor 4
27918
0.22
chr4_141015619_141015856 0.22 RP11-392B6.1

33432
0.2
chr1_95561573_95561724 0.21 TMEM56
transmembrane protein 56
21246
0.11
chr5_126147731_126147991 0.21 LMNB1
lamin B1
34980
0.19
chr6_41528112_41529137 0.21 FOXP4
forkhead box P4
4863
0.19
chr1_11785555_11785706 0.21 AGTRAP
angiotensin II receptor-associated protein
10511
0.12
chr1_249111594_249111745 0.21 SH3BP5L
SH3-binding domain protein 5-like
397
0.81
chrX_136650028_136650459 0.21 ZIC3
Zic family member 3
1566
0.39
chrX_153190817_153191535 0.21 ARHGAP4
Rho GTPase activating protein 4
522
0.6
chr11_58989802_58989953 0.21 ENSG00000263999
.
7705
0.17
chrX_118818753_118818904 0.21 SEPT6
septin 6
7964
0.18
chr5_118606885_118607036 0.21 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
2511
0.28
chr2_65245033_65245279 0.21 AC007386.4

19475
0.14
chr14_102276711_102277223 0.21 CTD-2017C7.2

309
0.73
chr3_36937412_36937563 0.21 TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
37113
0.17
chr14_68320261_68320412 0.21 RAD51B
RAD51 paralog B
30075
0.16
chr1_111415846_111416285 0.21 CD53
CD53 molecule
289
0.91
chrX_1600809_1601304 0.21 ASMTL
acetylserotonin O-methyltransferase-like
28401
0.16
chr8_133770966_133771357 0.21 TMEM71
transmembrane protein 71
1633
0.38
chr7_37488846_37488997 0.21 ELMO1
engulfment and cell motility 1
69
0.98
chr3_108543496_108543820 0.21 TRAT1
T cell receptor associated transmembrane adaptor 1
2039
0.42
chr3_128710945_128711096 0.21 KIAA1257
KIAA1257
280
0.88
chr5_176326174_176326325 0.21 HK3
hexokinase 3 (white cell)
84
0.98
chr19_42249623_42249774 0.21 CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
5187
0.14
chr9_129235089_129235240 0.21 ENSG00000252985
.
45992
0.13
chrX_53711459_53711652 0.21 HUWE1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
441
0.89
chr8_126447584_126447735 0.21 TRIB1
tribbles pseudokinase 1
1871
0.39
chr12_116723741_116723892 0.21 MED13L
mediator complex subunit 13-like
8673
0.24
chr3_10334877_10335066 0.21 GHRL
ghrelin/obestatin prepropeptide
340
0.8
chr8_82022969_82023806 0.20 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
916
0.72
chr19_50062782_50062933 0.20 NOSIP
nitric oxide synthase interacting protein
1030
0.27
chr19_7268349_7268500 0.20 INSR
insulin receptor
25518
0.17
chr6_24934739_24934890 0.20 FAM65B
family with sequence similarity 65, member B
1374
0.5
chr13_24146066_24146217 0.20 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
1338
0.59
chr1_100852790_100852941 0.20 ENSG00000216067
.
8534
0.21
chr6_107154119_107154270 0.20 ENSG00000202285
.
32735
0.17
chr12_8666250_8666401 0.20 CLEC4D
C-type lectin domain family 4, member D
189
0.93

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.4 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.4 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.5 GO:0001878 response to yeast(GO:0001878)
0.1 0.4 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.2 GO:0045588 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.2 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.3 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.3 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1 0.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:0045116 protein neddylation(GO:0045116)
0.1 0.2 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.1 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.2 GO:0045056 transcytosis(GO:0045056)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0052556 positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.2 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.2 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.2 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.2 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.4 GO:0033363 secretory granule organization(GO:0033363)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.3 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.4 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.2 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.2 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0010870 positive regulation of receptor biosynthetic process(GO:0010870)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0045715 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714) negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:0002902 regulation of B cell apoptotic process(GO:0002902) negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0045713 low-density lipoprotein particle receptor biosynthetic process(GO:0045713)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.0 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.0 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.0 0.1 GO:0036230 granulocyte activation(GO:0036230)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0010665 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.0 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.0 GO:0052251 modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 1.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0090200 positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0048668 collateral sprouting(GO:0048668) regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.0 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0034123 positive regulation of toll-like receptor signaling pathway(GO:0034123)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0051225 spindle assembly(GO:0051225)
0.0 0.1 GO:0032615 interleukin-12 production(GO:0032615)
0.0 0.0 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.0 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0032401 establishment of melanosome localization(GO:0032401)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.0 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.1 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.1 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.1 GO:0014002 astrocyte development(GO:0014002)
0.0 0.0 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.3 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0033003 regulation of mast cell activation(GO:0033003)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.0 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0097191 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693) interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.0 GO:0045576 mast cell activation(GO:0045576)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0031297 replication fork processing(GO:0031297)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.0 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.4 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 0.0 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.2 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.0 GO:0030202 heparin metabolic process(GO:0030202)
0.0 0.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.0 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.5 GO:1902400 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0034311 diol metabolic process(GO:0034311)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.0 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.0 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.0 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.0 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0009148 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051) pyrimidine ribonucleoside biosynthetic process(GO:0046132)
0.0 0.0 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.3 GO:0042629 mast cell granule(GO:0042629)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.7 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 1.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0060198 clathrin-sculpted vesicle(GO:0060198)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.5 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0001846 opsonin binding(GO:0001846)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0032357 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.5 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0015923 mannosidase activity(GO:0015923)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.0 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.7 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.0 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.1 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.0 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.1 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.0 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.1 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription