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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EP300

Z-value: 0.94

Motif logo

Transcription factors associated with EP300

Gene Symbol	Gene ID	Gene Info
EP300 Ensembl NCBI GeneCards UniProt	ENSG00000100393.9	EP300

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
EP300	chr22_41487816_41488241	238	0.703455	-0.40	2.9e-01	Click!
EP300	chr22_41486838_41487071	836	0.444808	-0.26	5.1e-01	Click!
EP300	chr22_41487155_41487362	532	0.611224	0.06	8.8e-01	Click!

Activity of the EP300 motif across conditions

Conditions sorted by the z-value of the EP300 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_21462508_21463481	0.69	NEBL-AS1	NEBL antisense RNA 1	51	0.59
chr1_180881914_180882730	0.65	KIAA1614	KIAA1614	3	0.98
chr19_45995836_45996758	0.63	RTN2	reticulon 2	228	0.87
chr11_131780761_131781452	0.61	NTM	neurotrimin	209	0.95
chr1_68697735_68698156	0.59	WLS	wntless Wnt ligand secretion mediator	18	0.98
chr8_15397591_15398115	0.59	TUSC3	tumor suppressor candidate 3	61	0.98
chr14_105436556_105437076	0.57	AHNAK2	AHNAK nucleoprotein 2	7878	0.16
chr6_46702576_46703631	0.56	PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	24	0.97
chr11_706564_706815	0.55	EPS8L2	EPS8-like 2	60	0.94
chr20_9048816_9049419	0.55	PLCB4	phospholipase C, beta 4	293	0.9
chr1_81703498_81704139	0.54	ENSG00000223026	.	13656	0.28
chr22_30831807_30831958	0.53	MTFP1	mitochondrial fission process 1	10077	0.07
chr18_11149170_11149978	0.51	PIEZO2	piezo-type mechanosensitive ion channel component 2	987	0.72
chr20_23617810_23618640	0.48	CST3	cystatin C	357	0.87
chr17_36610454_36610862	0.48	ENSG00000260833	.	1970	0.27
chr4_121842864_121843514	0.46	PRDM5	PR domain containing 5	815	0.75
chr14_88789378_88789974	0.46	KCNK10	potassium channel, subfamily K, member 10	83	0.98
chr14_79745937_79746359	0.44	NRXN3	neurexin 3	101	0.98
chr4_30719321_30719743	0.42	PCDH7	protocadherin 7	2505	0.43
chr13_98866468_98866619	0.41	ENSG00000263399	.	5765	0.17
chr9_129884150_129884930	0.41	ANGPTL2	angiopoietin-like 2	373	0.9
chr17_43249136_43249303	0.40	RP13-890H12.2		268	0.83
chr3_149374149_149374556	0.40	WWTR1-AS1	WWTR1 antisense RNA 1	455	0.65
chr18_31020374_31020722	0.40	CCDC178	coiled-coil domain containing 178	109	0.98
chr8_122653551_122653742	0.40	HAS2	hyaluronan synthase 2	16	0.5
chr13_100608335_100608708	0.39	ZIC5	Zic family member 5	15642	0.18
chr17_79485709_79486744	0.39	RP13-766D20.2		160	0.9
chr8_145925356_145925968	0.38	AF186192.5		5257	0.15
chr1_50489142_50489611	0.38	AGBL4	ATP/GTP binding protein-like 4	196	0.94
chrX_114467670_114468385	0.37	LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	601	0.77
chr22_37957123_37957770	0.37	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	959	0.43
chr13_99330080_99330373	0.37	ENSG00000243366	.	5992	0.26
chr6_5999099_5999932	0.37	NRN1	neuritin 1	7685	0.26
chr12_20522500_20522819	0.36	PDE3A	phosphodiesterase 3A, cGMP-inhibited	480	0.52
chr7_5458775_5459294	0.36	AC093620.5		424	0.46
chr1_27357912_27358708	0.36	FAM46B	family with sequence similarity 46, member B	18983	0.16
chr9_40632604_40633916	0.36	SPATA31A3	SPATA31 subfamily A, member 3	67031	0.14
chr20_36846491_36846985	0.36	KIAA1755	KIAA1755	8883	0.19
chr9_16869822_16870309	0.35	BNC2	basonuclin 2	639	0.83
chr2_142887906_142888379	0.35	LRP1B	low density lipoprotein receptor-related protein 1B	432	0.87
chr8_97602452_97602809	0.35	SDC2	syndecan 2	4015	0.32
chr8_145022986_145023296	0.35	PLEC	plectin	1903	0.2
chr9_43685064_43685767	0.35	CNTNAP3B	contactin associated protein-like 3B	505	0.86
chr19_6076963_6077580	0.35	CTC-232P5.3		9307	0.15
chr21_31311288_31312406	0.34	GRIK1	glutamate receptor, ionotropic, kainate 1	3	0.99
chr1_221057671_221057822	0.34	HLX	H2.0-like homeobox	3162	0.25
chr12_58129779_58130334	0.34	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	1563	0.16
chr1_95006423_95007262	0.34	F3	coagulation factor III (thromboplastin, tissue factor)	351	0.93
chr13_20175736_20176974	0.33	MPHOSPH8	M-phase phosphoprotein 8	31433	0.18
chr15_101708121_101708357	0.33	RP11-505E24.2		81968	0.08
chr11_3181654_3181858	0.33	OSBPL5	oxysterol binding protein-like 5	867	0.55
chrX_8699533_8700279	0.33	KAL1	Kallmann syndrome 1 sequence	321	0.94
chr7_5469244_5469831	0.33	TNRC18	trinucleotide repeat containing 18	4492	0.16
chr6_26757700_26757961	0.33	GUSBP2	glucuronidase, beta pseudogene 2	88787	0.07
chr2_64586886_64587176	0.33	ENSG00000264297	.	19138	0.23
chr17_15851287_15851438	0.33	ADORA2B	adenosine A2b receptor	3131	0.25
chr1_86047684_86048329	0.32	CYR61	cysteine-rich, angiogenic inducer, 61	1562	0.37
chr14_105434639_105435137	0.32	AHNAK2	AHNAK nucleoprotein 2	9806	0.16
chr3_159483400_159483608	0.32	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough	612	0.7
chr10_116164052_116164623	0.32	AFAP1L2	actin filament associated protein 1-like 2	77	0.98
chr17_1961906_1962057	0.32	HIC1	hypermethylated in cancer 1	2377	0.14
chr5_17219309_17219681	0.31	BASP1	brain abundant, membrane attached signal protein 1	1826	0.3
chr16_81480914_81481100	0.31	CMIP	c-Maf inducing protein	2232	0.39
chr8_6691754_6692464	0.31	DEFB1	defensin, beta 1	43435	0.14
chr7_19155713_19156221	0.31	TWIST1	twist family bHLH transcription factor 1	1328	0.36
chr11_89027115_89027763	0.31	TYR	tyrosinase	116819	0.06
chr22_47149775_47150260	0.31	CTA-29F11.1		8443	0.18
chr22_36768110_36768261	0.31	MYH9	myosin, heavy chain 9, non-muscle	7028	0.2
chr15_102182223_102182374	0.31	ENSG00000252614	.	6217	0.18
chr6_37227035_37227379	0.31	TBC1D22B	TBC1 domain family, member 22B	1659	0.28
chr12_132111092_132111243	0.31	ENSG00000212154	.	34441	0.2
chr4_107956832_107957922	0.30	DKK2	dickkopf WNT signaling pathway inhibitor 2	77	0.99
chrX_85403501_85403824	0.30	DACH2	dachshund homolog 2 (Drosophila)	37	0.99
chr12_6493326_6493955	0.30	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)	221	0.89
chr1_31380173_31380807	0.30	SDC3	syndecan 3	1118	0.44
chr11_12309017_12309498	0.30	MICALCL	MICAL C-terminal like	810	0.62
chr9_39817132_39817490	0.30	SPATA31A2	SPATA31 subfamily A, member 2	67664	0.13
chr19_37743129_37743340	0.29	ZNF383	zinc finger protein 383	24782	0.13
chr9_130159461_130160475	0.29	SLC2A8	solute carrier family 2 (facilitated glucose transporter), member 8	305	0.87
chr20_6750709_6750962	0.29	BMP2	bone morphogenetic protein 2	2524	0.43
chr2_144694678_144695023	0.29	AC016910.1		210	0.96
chr7_193532_193958	0.29	AC093627.12		435	0.67
chr11_45067778_45067990	0.29	PRDM11	PR domain containing 11	47680	0.17
chr3_96531977_96533205	0.29	EPHA6	EPH receptor A6	834	0.76
chr6_113970107_113970350	0.29	ENSG00000266650	.	46111	0.16
chr19_41699238_41699877	0.29	CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1	405	0.76
chr4_90580974_90581125	0.29	RP11-115D19.1		21614	0.27
chr1_161195725_161196723	0.29	TOMM40L	translocase of outer mitochondrial membrane 40 homolog (yeast)-like	130	0.84
chr20_62318086_62318558	0.29	RTEL1	regulator of telomere elongation helicase 1	1370	0.24
chrX_3061320_3061471	0.29	ARSF	arylsulfatase F	76521	0.09
chr12_130645923_130646373	0.28	FZD10	frizzled family receptor 10	856	0.76
chr12_104998031_104998607	0.28	ENSG00000264295	.	12908	0.23
chr8_122652196_122652655	0.28	HAS2-AS1	HAS2 antisense RNA 1	283	0.88
chr16_73090314_73090763	0.28	ZFHX3	zinc finger homeobox 3	3059	0.3
chr20_50721484_50721986	0.28	ZFP64	ZFP64 zinc finger protein	273	0.95
chr9_39287873_39288256	0.28	CNTNAP3	contactin associated protein-like 3	28	0.99
chr15_83952244_83952401	0.28	BNC1	basonuclin 1	251	0.94
chr7_42533030_42533218	0.28	GLI3	GLI family zinc finger 3	256466	0.02
chr11_104034118_104035249	0.28	PDGFD	platelet derived growth factor D	152	0.98
chr5_176921454_176921726	0.28	RP11-1334A24.6		406	0.7
chr13_52419076_52419304	0.28	CCDC70	coiled-coil domain containing 70	16927	0.19
chr19_49653084_49654050	0.28	PPFIA3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	2209	0.15
chr4_122686341_122686757	0.28	TMEM155	transmembrane protein 155	33	0.94
chr5_118406793_118407698	0.28	DMXL1	Dmx-like 1	6	0.92
chr13_80913760_80914290	0.28	SPRY2	sprouty homolog 2 (Drosophila)	218	0.96
chr3_125985987_125986785	0.28	ALDH1L1-AS2	ALDH1L1 antisense RNA 2	60288	0.1
chr1_956379_957022	0.28	AGRN	agrin	1197	0.27
chr22_46933754_46934840	0.27	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1	1230	0.46
chr22_23487771_23487960	0.27	RAB36	RAB36, member RAS oncogene family	312	0.69
chr10_76683945_76684144	0.27	KAT6B	K(lysine) acetyltransferase 6B	85586	0.08
chr7_20391312_20391720	0.27	CTA-293F17.1		20146	0.18
chr8_87188863_87189124	0.27	CTD-3118D11.3		3654	0.25
chr17_55950685_55950914	0.27	CUEDC1	CUE domain containing 1	768	0.63
chr19_13166621_13166875	0.27	AC007787.2		15440	0.1
chr9_65576390_65577630	0.27	SPATA31A7	SPATA31 subfamily A, member 7	67400	0.15
chr1_33366734_33367013	0.27	TMEM54	transmembrane protein 54	86	0.96
chr17_79370689_79371194	0.27	RP11-1055B8.6	Uncharacterized protein	1666	0.23
chr4_6889699_6890105	0.27	TBC1D14	TBC1 domain family, member 14	21067	0.18
chrX_70365452_70365975	0.27	NLGN3	neuroligin 3	1001	0.39
chr22_36310772_36312004	0.27	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	23557	0.25
chr2_223182895_223183757	0.27	AC010980.2		330	0.89
chr1_59043269_59043420	0.27	TACSTD2	tumor-associated calcium signal transducer 2	178	0.95
chr3_79068024_79068175	0.27	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	66	0.99
chr19_49118590_49118741	0.27	FAM83E	family with sequence similarity 83, member E	593	0.5
chr22_46403073_46403407	0.26	WNT7B	wingless-type MMTV integration site family, member 7B	30231	0.1
chr4_139160727_139161292	0.26	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	2494	0.42
chr11_85645675_85646031	0.26	RP11-90K17.2		11128	0.21
chr21_40297838_40298298	0.26	ENSG00000272015	.	31359	0.23
chr3_61546098_61546562	0.26	PTPRG	protein tyrosine phosphatase, receptor type, G	1255	0.64
chr2_45926255_45926465	0.26	U51244.2		23745	0.22
chr11_101453394_101453891	0.26	TRPC6	transient receptor potential cation channel, subfamily C, member 6	592	0.84
chr22_40391903_40392054	0.26	FAM83F	family with sequence similarity 83, member F	1025	0.52
chr3_149093384_149093535	0.26	TM4SF1	transmembrane 4 L six family member 1	40	0.97
chr7_107641976_107642307	0.26	LAMB1	laminin, beta 1	331	0.84
chr22_50698815_50699396	0.26	MAPK12	mitogen-activated protein kinase 12	632	0.49
chr22_39319816_39319977	0.26	APOBEC3A	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	28860	0.11
chr8_77318715_77319027	0.26	ENSG00000222231	.	140904	0.05
chr7_70159815_70160908	0.25	AUTS2	autism susceptibility candidate 2	33764	0.25
chr8_494269_494491	0.25	TDRP	testis development related protein	457	0.88
chr9_34651822_34652525	0.25	IL11RA	interleukin 11 receptor, alpha	16	0.94
chr1_16479586_16479939	0.25	RP11-276H7.2		1944	0.21
chr15_61520624_61520983	0.25	RORA	RAR-related orphan receptor A	715	0.73
chr7_83278228_83278460	0.25	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	18	0.99
chr18_34834231_34834654	0.25	CELF4	CUGBP, Elav-like family member 4	10275	0.2
chr18_59617014_59617243	0.25	RNF152	ring finger protein 152	55664	0.17
chr20_10652975_10654015	0.25	RP11-103J8.1		81	0.96
chr4_5039624_5039775	0.25	STK32B	serine/threonine kinase 32B	13470	0.23
chr18_24236408_24236707	0.25	KCTD1	potassium channel tetramerization domain containing 1	808	0.43
chr12_94638760_94639060	0.25	PLXNC1	plexin C1	9384	0.19
chr2_217555825_217556381	0.25	AC007563.5		3084	0.22
chr9_41433170_41433957	0.25	SPATA31A5	SPATA31 subfamily A, member 5	67116	0.13
chr11_70963231_70963444	0.25	SHANK2	SH3 and multiple ankyrin repeat domains 2	286	0.94
chr1_159111648_159111897	0.25	AIM2	absent in melanoma 2	1474	0.37
chr17_40563503_40563724	0.25	PTRF	polymerase I and transcript release factor	11922	0.1
chr5_153990189_153990659	0.25	ENSG00000264760	.	14792	0.21
chr2_206549618_206550045	0.24	NRP2	neuropilin 2	1816	0.48
chr2_221969079_221969387	0.24	EPHA4	EPH receptor A4	398047	0.01
chr2_114643988_114644188	0.24	ACTR3	ARP3 actin-related protein 3 homolog (yeast)	3449	0.28
chrX_136647964_136648621	0.24	ZIC3	Zic family member 3	9	0.97
chr7_90896542_90897161	0.24	FZD1	frizzled family receptor 1	3068	0.42
chr10_71561624_71562119	0.24	COL13A1	collagen, type XIII, alpha 1	3	0.98
chr9_109625885_109626257	0.24	ZNF462	zinc finger protein 462	624	0.77
chr4_54974366_54974565	0.24	ENSG00000221219	.	4642	0.18
chr7_100488744_100488895	0.24	UFSP1	UFM1-specific peptidase 1 (non-functional)	1480	0.22
chr7_75923830_75924012	0.24	ENSG00000263569	.	5813	0.16
chr17_70118510_70118661	0.24	SOX9	SRY (sex determining region Y)-box 9	1424	0.58
chr18_31738936_31739121	0.24	NOL4	nucleolar protein 4	63028	0.13
chr19_39149026_39149198	0.24	ACTN4	actinin, alpha 4	10734	0.12
chr2_158113918_158114875	0.24	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	286	0.93
chr2_1746603_1747283	0.23	PXDN	peroxidasin homolog (Drosophila)	1271	0.58
chr16_89386869_89387175	0.23	AC137932.6		519	0.71
chr3_151023495_151023662	0.23	GPR87	G protein-coupled receptor 87	11162	0.16
chr5_40411204_40411410	0.23	ENSG00000265615	.	90887	0.09
chr17_76879212_76879961	0.23	TIMP2	TIMP metallopeptidase inhibitor 2	9354	0.14
chr5_55193656_55194061	0.23	AC008914.1	Uncharacterized protein	30711	0.14
chr16_16316841_16317488	0.23	ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	157	0.66
chr5_14205024_14205555	0.23	TRIO	trio Rho guanine nucleotide exchange factor	21382	0.29
chr2_150186573_150186784	0.23	LYPD6	LY6/PLAUR domain containing 6	179	0.97
chr20_43729394_43729952	0.23	KCNS1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	77	0.96
chr12_60546788_60546939	0.23	ENSG00000264437	.	126225	0.06
chr17_18139215_18139404	0.23	FLII	flightless I homolog (Drosophila)	10067	0.11
chr12_54090682_54090833	0.23	CALCOCO1	calcium binding and coiled-coil domain 1	17656	0.15
chr9_139715640_139716017	0.23	RABL6	RAB, member RAS oncogene family-like 6	47	0.93
chr22_30652065_30652410	0.23	LIF	leukemia inhibitory factor	9397	0.1
chr4_1035336_1035962	0.23	FGFRL1	fibroblast growth factor receptor-like 1	29410	0.11
chr1_31886727_31887046	0.23	SERINC2	serine incorporator 2	226	0.92
chr18_47087336_47087671	0.23	LIPG	lipase, endothelial	39	0.97
chr1_218522781_218522932	0.22	TGFB2	transforming growth factor, beta 2	3279	0.27
chr8_64133185_64133371	0.22	ENSG00000241964	.	14191	0.24
chr2_98962891_98963586	0.22	AC092675.4		220	0.79
chr6_170604225_170605407	0.22	FAM120B	family with sequence similarity 120B	407	0.83
chr1_220959785_220960305	0.22	MARC1	mitochondrial amidoxime reducing component 1	56	0.98
chr7_28725072_28725301	0.22	CREB5	cAMP responsive element binding protein 5	412	0.92
chr13_99404271_99404634	0.22	SLC15A1	solute carrier family 15 (oligopeptide transporter), member 1	456	0.86
chr19_45843770_45844284	0.22	KLC3	kinesin light chain 3	5	0.95
chr17_27482435_27482735	0.22	RP11-321A17.4		15084	0.15
chr2_150187104_150187520	0.22	LYPD6	LY6/PLAUR domain containing 6	261	0.96
chr9_110250307_110251795	0.22	KLF4	Kruppel-like factor 4 (gut)	360	0.89
chr20_47391125_47391276	0.22	ENSG00000251876	.	35215	0.19
chr8_23754300_23754592	0.22	STC1	stanniocalcin 1	42126	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EP300

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0003181	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.1	0.4	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.4	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.3	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.3	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.1	0.2	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.4	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.3	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.1	0.4	GO:0060437	lung growth(GO:0060437)
0.1	0.3	GO:0071436	sodium ion export(GO:0071436)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.2	GO:0060685	regulation of prostatic bud formation(GO:0060685)
0.1	0.2	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.2	GO:0019532	oxalate transport(GO:0019532)
0.1	0.3	GO:0009414	response to water deprivation(GO:0009414)
0.1	0.2	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	0.2	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.2	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.1	0.1	GO:0071071	regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1	0.1	GO:0090103	cochlea morphogenesis(GO:0090103)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.2	GO:0009648	photoperiodism(GO:0009648)
0.0	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.1	GO:0021508	floor plate formation(GO:0021508)
0.0	0.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.3	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.0	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.3	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.0	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347) regulation of steroid hormone biosynthetic process(GO:0090030)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0048343	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0051323	metaphase(GO:0051323)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.3	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.3	GO:0010984	regulation of lipoprotein particle clearance(GO:0010984)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0010523	negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0010658	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.6	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.2	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.8	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.3	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.3	GO:0051567	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.1	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0060536	trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0	0.2	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.4	GO:0098876	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.4	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.2	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.3	GO:0051953	negative regulation of amine transport(GO:0051953)
0.0	0.2	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0006168	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.3	GO:0051966	regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0	0.4	GO:0038061	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.3	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.1	GO:0071397	cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.0	0.1	GO:0030147	obsolete natriuresis(GO:0030147)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.3	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.0	GO:0072141	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.4	GO:0007566	embryo implantation(GO:0007566)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.2	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.0	GO:0010996	response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0	0.0	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.3	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.3	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.2	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0021779	oligodendrocyte cell fate commitment(GO:0021779)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.0	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.2	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.0	GO:0045683	negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of epidermis development(GO:0045683)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.2	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.0	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.0	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0071453	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.2	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.0	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.5	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.0	GO:0055117	regulation of cardiac muscle contraction(GO:0055117)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.0	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.0	0.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.2	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.0	0.1	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.1	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.2	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0014015	positive regulation of gliogenesis(GO:0014015)
0.0	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0060603	mammary gland duct morphogenesis(GO:0060603)
0.0	0.2	GO:0030901	midbrain development(GO:0030901)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.1	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.0	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0048265	response to pain(GO:0048265)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.0	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.1	GO:0006577	amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0	0.0	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.2	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.1	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.0	GO:0033194	response to hydroperoxide(GO:0033194)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.3	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.4	GO:0030315	T-tubule(GO:0030315)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.6	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.3	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.6	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.7	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	1.5	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.3	GO:0030018	Z disc(GO:0030018)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.7	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0005605	basal lamina(GO:0005605)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.2	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.0	GO:0043218	compact myelin(GO:0043218)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.5	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	0.3	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.5	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.3	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.6	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.2	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1	0.2	GO:0002060	purine nucleobase binding(GO:0002060)
0.1	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.5	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.1	0.5	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.0	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.2	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.3	GO:0005536	glucose binding(GO:0005536)
0.0	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.3	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.2	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.6	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.3	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.2	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0016594	glycine binding(GO:0016594)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.0	GO:0042805	actinin binding(GO:0042805)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.3	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.5	GO:0051015	actin filament binding(GO:0051015)
0.0	0.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.0	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.0	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.5	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.4	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.1	ST ADRENERGIC	Adrenergic Pathway
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.8	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.5	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.0	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression