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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for EPAS1_BCL3

Z-value: 2.52

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Transcription factors associated with EPAS1_BCL3

Gene Symbol	Gene ID	Gene Info
EPAS1 Ensembl NCBI GeneCards UniProt	ENSG00000116016.9	endothelial PAS domain protein 1
BCL3 Ensembl NCBI GeneCards UniProt	ENSG00000069399.8	BCL3 transcription coactivator

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr19_45256342_45256683	BCL3	1934	0.204451	-0.86	2.9e-03	Click!
chr19_45250951_45251364	BCL3	647	0.567020	-0.85	3.4e-03	Click!
chr19_45258275_45258481	BCL3	3800	0.132638	-0.85	3.6e-03	Click!
chr19_45257252_45257704	BCL3	2900	0.152038	-0.82	6.2e-03	Click!
chr19_45256798_45256993	BCL3	2317	0.176735	-0.81	7.6e-03	Click!
chr2_46524572_46524838	EPAS1	164	0.971380	-0.61	8.4e-02	Click!
chr2_46523894_46524304	EPAS1	352	0.921263	-0.60	8.4e-02	Click!
chr2_46547328_46547516	EPAS1	22881	0.232308	0.60	8.5e-02	Click!
chr2_46497095_46497294	EPAS1	26553	0.225931	0.59	9.7e-02	Click!
chr2_46547628_46547783	EPAS1	23164	0.231436	0.57	1.1e-01	Click!

Activity of the EPAS1_BCL3 motif across conditions

Conditions sorted by the z-value of the EPAS1_BCL3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_12309017_12309498	2.42	MICALCL	MICAL C-terminal like	810	0.62
chr1_32044138_32044454	1.76	TINAGL1	tubulointerstitial nephritis antigen-like 1	2157	0.23
chr19_3606102_3607092	1.62	TBXA2R	thromboxane A2 receptor	61	0.89
chr7_112725821_112726406	1.58	GPR85	G protein-coupled receptor 85	280	0.92
chr16_51184635_51185066	1.48	SALL1	spalt-like transcription factor 1	302	0.89
chrX_107179250_107179655	1.43	RP6-191P20.4		242	0.93
chr11_118478413_118479735	1.41	PHLDB1	pleckstrin homology-like domain, family B, member 1	716	0.54
chr9_18474095_18474958	1.41	ADAMTSL1	ADAMTS-like 1	295	0.95
chr3_133748166_133748506	1.40	SLCO2A1	solute carrier organic anion transporter family, member 2A1	422	0.9
chr19_10120368_10120847	1.39	COL5A3	collagen, type V, alpha 3	540	0.61
chr1_31380173_31380807	1.27	SDC3	syndecan 3	1118	0.44
chr7_94025506_94025990	1.27	COL1A2	collagen, type I, alpha 2	1875	0.46
chr19_19383372_19383777	1.24	TM6SF2	transmembrane 6 superfamily member 2	523	0.66
chr17_36609355_36609985	1.23	ENSG00000260833	.	982	0.5
chr18_32290517_32290846	1.23	DTNA	dystrobrevin, alpha	420	0.9
chr2_190041307_190041749	1.21	COL5A2	collagen, type V, alpha 2	3077	0.31
chr1_75138923_75139762	1.21	C1orf173	chromosome 1 open reading frame 173	80	0.98
chr5_136833711_136834156	1.20	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	314	0.93
chr1_112532383_112532987	1.20	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	908	0.69
chr15_37391316_37391907	1.19	MEIS2	Meis homeobox 2	14	0.54
chr7_132260669_132261651	1.13	PLXNA4	plexin A4	69	0.98
chr9_130639317_130639975	1.13	AK1	adenylate kinase 1	376	0.71
chr1_205648469_205649627	1.13	SLC45A3	solute carrier family 45, member 3	539	0.74
chr17_59476045_59476898	1.08	RP11-332H18.4		260	0.74
chr6_163817634_163818149	1.07	QKI	QKI, KH domain containing, RNA binding	17784	0.29
chr6_166401265_166401649	1.07	ENSG00000252196	.	45628	0.17
chr12_86229562_86230264	1.05	RASSF9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	435	0.89
chr11_79151624_79152198	1.05	TENM4	teneurin transmembrane protein 4	216	0.95
chr19_41195138_41195302	1.02	NUMBL	numb homolog (Drosophila)-like	277	0.86
chr1_156647773_156647946	1.01	NES	nestin	670	0.5
chr13_58203621_58204059	1.00	PCDH17	protocadherin 17	2815	0.43
chr4_24472696_24473642	1.00	ENSG00000265001	.	41714	0.15
chr8_69242814_69243988	0.98	C8orf34	chromosome 8 open reading frame 34	56	0.82
chr12_115889903_115890336	0.98	RP11-116D17.1	HCG2038717; Uncharacterized protein	89302	0.1
chr16_88219567_88219948	0.98	BANP	BTG3 associated nuclear protein	216133	0.02
chr8_49831086_49831370	0.97	SNAI2	snail family zinc finger 2	2760	0.41
chr12_72665374_72665945	0.96	ENSG00000236333	.	112	0.93
chr11_132953015_132953394	0.95	OPCML	opioid binding protein/cell adhesion molecule-like	139541	0.05
chr18_53089837_53090372	0.95	TCF4	transcription factor 4	361	0.89
chr19_16179581_16179939	0.95	TPM4	tropomyosin 4	1250	0.44
chr17_31255969_31256206	0.95	TMEM98	transmembrane protein 98	859	0.62
chr22_36232996_36233711	0.94	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	2912	0.37
chr2_105458782_105459564	0.94	LINC01158	long intergenic non-protein coding RNA 1158	8738	0.14
chr10_118033216_118033536	0.93	GFRA1	GDNF family receptor alpha 1	397	0.9
chr6_13733598_13733910	0.92	RANBP9	RAN binding protein 9	21958	0.19
chr2_206549618_206550045	0.92	NRP2	neuropilin 2	1816	0.48
chr13_98796347_98796640	0.92	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	759	0.68
chr16_2077067_2078193	0.92	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	701	0.35
chr8_145910346_145910740	0.91	ARHGAP39	Rho GTPase activating protein 39	651	0.64
chr1_29563184_29564088	0.90	PTPRU	protein tyrosine phosphatase, receptor type, U	485	0.75
chr17_20491916_20492779	0.89	CDRT15L2	CMT1A duplicated region transcript 15-like 2	9310	0.21
chr11_57406082_57406969	0.88	AP000662.4		676	0.5
chr8_89340038_89340774	0.88	MMP16	matrix metallopeptidase 16 (membrane-inserted)	152	0.73
chr20_9049623_9049963	0.87	PLCB4	phospholipase C, beta 4	45	0.98
chr17_80339190_80339423	0.85	UTS2R	urotensin 2 receptor	7153	0.1
chr11_118492062_118492969	0.85	PHLDB1	pleckstrin homology-like domain, family B, member 1	14157	0.11
chr1_153584096_153584410	0.84	S100A16	S100 calcium binding protein A16	1306	0.22
chr1_151913762_151913913	0.84	THEM4	thioesterase superfamily member 4	31553	0.11
chr1_33219625_33220407	0.84	KIAA1522	KIAA1522	394	0.82
chr12_118626563_118627015	0.84	TAOK3	TAO kinase 3	1538	0.42
chr5_115790032_115790655	0.84	CTB-118N6.3		4917	0.26
chr12_3069053_3070004	0.84	TEAD4	TEA domain family member 4	445	0.77
chr6_105388737_105389249	0.83	LIN28B	lin-28 homolog B (C. elegans)	15930	0.23
chr2_218843405_218844030	0.82	TNS1	tensin 1	60	0.79
chr10_132588844_132588995	0.81	ENSG00000264803	.	172012	0.04
chr18_52495652_52496658	0.81	RAB27B	RAB27B, member RAS oncogene family	725	0.77
chr8_42063953_42065062	0.81	PLAT	plasminogen activator, tissue	576	0.71
chr16_10922458_10922819	0.81	TVP23A	trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)	9996	0.18
chr1_45308302_45308945	0.80	PTCH2	patched 2	7	0.95
chr16_85268847_85269227	0.80	CTC-786C10.1		64155	0.11
chr22_29075189_29075804	0.78	TTC28	tetratricopeptide repeat domain 28	357	0.87
chr5_92918344_92919004	0.78	NR2F1	nuclear receptor subfamily 2, group F, member 1	369	0.84
chr6_170461369_170461520	0.78	RP11-302L19.1		16297	0.25
chr2_158120680_158120854	0.78	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	6657	0.24
chr3_112931196_112931871	0.78	BOC	BOC cell adhesion associated, oncogene regulated	124	0.97
chr3_147140468_147140953	0.78	ZIC1	Zic family member 1	13539	0.19
chr1_86042054_86042529	0.77	DDAH1	dimethylarginine dimethylaminohydrolase 1	1642	0.36
chr3_36805291_36805678	0.77	DCLK3	doublecortin-like kinase 3	24132	0.23
chr8_77594904_77595092	0.76	ZFHX4	zinc finger homeobox 4	236	0.67
chr2_187559481_187559668	0.76	AC017101.10		440	0.69
chr17_36621277_36621585	0.76	ARHGAP23	Rho GTPase activating protein 23	6749	0.17
chr7_19155713_19156221	0.75	TWIST1	twist family bHLH transcription factor 1	1328	0.36
chr13_24145710_24146057	0.75	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1080	0.66
chr14_42076336_42076756	0.75	LRFN5	leucine rich repeat and fibronectin type III domain containing 5	227	0.95
chr14_86000741_86001075	0.74	FLRT2	fibronectin leucine rich transmembrane protein 2	4336	0.28
chr7_87257054_87258255	0.74	RUNDC3B	RUN domain containing 3B	75	0.97
chr10_33621519_33621932	0.73	NRP1	neuropilin 1	1585	0.49
chr2_11272894_11273725	0.73	C2orf50	chromosome 2 open reading frame 50	54	0.98
chr17_47077080_47077320	0.73	IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	2092	0.16
chr19_13137554_13137705	0.73	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	1818	0.2
chr18_6729547_6730123	0.73	ARHGAP28	Rho GTPase activating protein 28	14	0.5
chr9_129884150_129884930	0.71	ANGPTL2	angiopoietin-like 2	373	0.9
chr4_158143046_158143598	0.71	GRIA2	glutamate receptor, ionotropic, AMPA 2	504	0.84
chr16_29231357_29231508	0.71	RP11-231C14.6		92239	0.06
chr6_41437651_41438276	0.71	RP11-328M4.2		75849	0.08
chr18_5629293_5629838	0.71	ENSG00000252432	.	32484	0.15
chr1_44513542_44514157	0.70	SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	16715	0.14
chr18_75239336_75239487	0.70	ENSG00000199392	.	95766	0.09
chr3_37903958_37904647	0.70	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	637	0.58
chr4_177711668_177712016	0.70	VEGFC	vascular endothelial growth factor C	2039	0.48
chr11_46300696_46300847	0.70	CREB3L1	cAMP responsive element binding protein 3-like 1	1543	0.37
chr8_142010048_142010787	0.69	PTK2	protein tyrosine kinase 2	619	0.8
chr16_55542879_55544136	0.69	LPCAT2	lysophosphatidylcholine acyltransferase 2	597	0.77
chr18_52763849_52764148	0.69	ENSG00000252437	.	49878	0.16
chr3_116163640_116163792	0.69	LSAMP	limbic system-associated membrane protein	114	0.98
chr18_31157392_31158104	0.68	ASXL3	additional sex combs like 3 (Drosophila)	848	0.76
chr22_24640119_24640309	0.68	GGT5	gamma-glutamyltransferase 5	813	0.59
chr9_71939475_71940274	0.68	FAM189A2	family with sequence similarity 189, member A2	386	0.91
chr6_82854353_82854866	0.68	ENSG00000223044	.	65548	0.14
chr1_214387403_214387935	0.67	SMYD2	SET and MYND domain containing 2	66907	0.13
chr3_129323468_129324020	0.67	PLXND1	plexin D1	1917	0.3
chr13_110960499_110960922	0.67	COL4A2	collagen, type IV, alpha 2	1096	0.42
chr12_3308931_3310293	0.67	TSPAN9	tetraspanin 9	729	0.75
chr11_48085341_48085729	0.66	ENSG00000263693	.	32799	0.16
chr6_75914274_75914680	0.66	COL12A1	collagen, type XII, alpha 1	1061	0.59
chr12_115341376_115341564	0.66	ENSG00000252459	.	165961	0.04
chr7_29763365_29763528	0.65	ENSG00000212024	.	43002	0.15
chr2_167232459_167233133	0.65	SCN9A	sodium channel, voltage-gated, type IX, alpha subunit	293	0.93
chr15_69168095_69168250	0.65	SPESP1	sperm equatorial segment protein 1	54667	0.11
chr5_58592476_58593460	0.65	PDE4D	phosphodiesterase 4D, cAMP-specific	21023	0.29
chr7_129933276_129933885	0.64	CPA4	carboxypeptidase A4	461	0.76
chr4_16900069_16900243	0.64	LDB2	LIM domain binding 2	29	0.99
chr9_16869370_16869521	0.64	BNC2	basonuclin 2	1259	0.62
chr1_33167424_33167698	0.64	SYNC	syncoilin, intermediate filament protein	800	0.55
chr5_88081093_88081351	0.64	MEF2C	myocyte enhancer factor 2C	38383	0.18
chr19_6740138_6741070	0.63	TRIP10	thyroid hormone receptor interactor 10	325	0.81
chr8_122653917_122654172	0.63	HAS2-AS1	HAS2 antisense RNA 1	368	0.53
chr12_79258716_79258905	0.63	SYT1	synaptotagmin I	218	0.97
chr13_101240923_101241511	0.63	GGACT	gamma-glutamylamine cyclotransferase	232	0.94
chr2_45182324_45182565	0.63	SIX3-AS1	SIX3 antisense RNA 1	13432	0.21
chr11_44899424_44899838	0.62	TSPAN18	tetraspanin 18	18477	0.25
chr19_2524704_2524855	0.62	ENSG00000252962	.	21640	0.14
chr5_133846660_133846957	0.62	ENSG00000240250	.	6693	0.16
chr3_8561489_8561767	0.62	LMCD1	LIM and cysteine-rich domains 1	17241	0.2
chr2_216297601_216297993	0.62	FN1	fibronectin 1	2993	0.27
chr13_34217183_34217463	0.61	RFC3	replication factor C (activator 1) 3, 38kDa	174863	0.03
chr17_7257720_7257871	0.61	RP11-542C16.1		468	0.42
chr9_68810140_68810583	0.61	ENSG00000266021	.	187123	0.03
chr12_116819979_116820276	0.61	ENSG00000264037	.	45996	0.17
chr22_37822529_37822680	0.61	RP1-63G5.5		876	0.37
chr11_63639243_63639445	0.61	MARK2	MAP/microtubule affinity-regulating kinase 2	2596	0.2
chr1_19973947_19974889	0.60	NBL1	neuroblastoma 1, DAN family BMP antagonist	314	0.87
chrX_70366066_70366529	0.60	NLGN3	neuroligin 3	1585	0.25
chr4_25309118_25309269	0.60	ZCCHC4	zinc finger, CCHC domain containing 4	5215	0.25
chr12_108991532_108991806	0.60	TMEM119	transmembrane protein 119	115	0.95
chr7_134451835_134452118	0.60	CALD1	caldesmon 1	12188	0.28
chr15_39876000_39876186	0.60	THBS1	thrombospondin 1	2799	0.26
chr1_21977639_21978366	0.60	RAP1GAP	RAP1 GTPase activating protein	327	0.9
chr5_95309703_95309854	0.60	ELL2	elongation factor, RNA polymerase II, 2	12003	0.19
chr5_88238184_88238467	0.59	MEF2C-AS1	MEF2C antisense RNA 1	579	0.83
chr1_118679267_118679564	0.59	SPAG17	sperm associated antigen 17	48431	0.18
chr19_434282_434433	0.59	SHC2	SHC (Src homology 2 domain containing) transforming protein 2	2177	0.2
chr10_13748513_13748974	0.59	ENSG00000222235	.	1765	0.25
chr14_85998039_85998552	0.59	FLRT2	fibronectin leucine rich transmembrane protein 2	1723	0.42
chrX_71933533_71934701	0.59	PHKA1	phosphorylase kinase, alpha 1 (muscle)	11	0.97
chr9_16626345_16626809	0.59	RP11-62F24.1		903	0.71
chr12_91574306_91575101	0.59	DCN	decorin	50	0.99
chr20_50177164_50177436	0.57	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	1868	0.48
chr7_55088250_55088401	0.57	EGFR	epidermal growth factor receptor	1514	0.55
chr1_213500802_213501077	0.57	RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1	276335	0.01
chr12_26277242_26278053	0.57	BHLHE41	basic helix-loop-helix family, member e41	413	0.76
chr11_7598410_7598701	0.57	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	284	0.91
chr10_63698495_63698899	0.56	ENSG00000221272	.	11920	0.25
chr5_15499822_15500142	0.56	FBXL7	F-box and leucine-rich repeat protein 7	323	0.94
chr4_150999769_151000790	0.56	DCLK2	doublecortin-like kinase 2	99	0.98
chr15_88799602_88799984	0.56	NTRK3	neurotrophic tyrosine kinase, receptor, type 3	132	0.98
chr1_164529222_164529675	0.56	PBX1	pre-B-cell leukemia homeobox 1	388	0.91
chr2_172963527_172963843	0.56	DLX2	distal-less homeobox 2	3943	0.24
chr5_155754238_155754771	0.56	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	737	0.81
chr4_129491193_129491344	0.55	ENSG00000238802	.	185913	0.03
chr4_159093168_159093728	0.55	RP11-597D13.9		281	0.64
chr19_56988243_56988602	0.55	ZNF667	zinc finger protein 667	65	0.96
chr8_58660875_58661197	0.55	ENSG00000252057	.	191892	0.03
chr2_11622794_11623343	0.55	E2F6	E2F transcription factor 6	16793	0.13
chr4_183369422_183369983	0.55	TENM3	teneurin transmembrane protein 3	450	0.89
chr1_200320777_200320954	0.55	ZNF281	zinc finger protein 281	58255	0.16
chr2_36923854_36924159	0.54	VIT	vitrin	3	0.98
chr9_10612773_10613124	0.54	PTPRD	protein tyrosine phosphatase, receptor type, D	225	0.97
chr3_32021796_32022649	0.54	OSBPL10	oxysterol binding protein-like 10	570	0.63
chr7_41740779_41741576	0.54	INHBA	inhibin, beta A	970	0.56
chr14_85995700_85996361	0.54	FLRT2	fibronectin leucine rich transmembrane protein 2	458	0.75
chr2_85020186_85020337	0.54	DUXAP1	double homeobox A pseudogene 1	42368	0.16
chr2_14772882_14773213	0.54	FAM84A	family with sequence similarity 84, member A	223	0.94
chr11_8891865_8892474	0.54	ST5	suppression of tumorigenicity 5	295	0.85
chr6_85482826_85483217	0.54	TBX18	T-box 18	8784	0.3
chr4_168154960_168155824	0.54	SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	25	0.99
chr9_34651822_34652525	0.54	IL11RA	interleukin 11 receptor, alpha	16	0.94
chr19_1524467_1524618	0.53	PLK5	polo-like kinase 5	416	0.64
chr8_22023419_22024083	0.53	BMP1	bone morphogenetic protein 1	951	0.4
chr10_72433024_72433359	0.53	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif, 14	632	0.79
chr17_70461490_70461782	0.53	ENSG00000200783	.	198655	0.03
chr20_9049976_9050220	0.53	PLCB4	phospholipase C, beta 4	350	0.89
chr17_31255277_31255844	0.53	TMEM98	transmembrane protein 98	332	0.89
chr19_13135354_13135619	0.53	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	45	0.95
chr20_36040630_36041025	0.53	SRC	v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog	28274	0.21
chr9_69146753_69147145	0.53	PGM5P2	phosphoglucomutase 5 pseudogene 2	545	0.82
chr5_88168642_88169029	0.53	MEF2C	myocyte enhancer factor 2C	4959	0.27
chr10_121013259_121013542	0.53	ENSG00000242853	.	41031	0.11
chr16_86542600_86543872	0.52	FOXF1	forkhead box F1	897	0.62
chr11_112125884_112126163	0.52	AP002884.2	LOC100132686 protein; Uncharacterized protein	4965	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0060677	ureteric bud elongation(GO:0060677)
0.4	1.1	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.3	1.1	GO:0043589	skin morphogenesis(GO:0043589)
0.3	0.8	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	1.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.5	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.2	1.2	GO:0021670	lateral ventricle development(GO:0021670)
0.2	0.7	GO:0060596	mammary placode formation(GO:0060596)
0.2	0.5	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	1.6	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	0.4	GO:0050932	regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942)
0.2	0.6	GO:0071294	cellular response to zinc ion(GO:0071294)
0.2	0.8	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.2	0.6	GO:0021508	floor plate formation(GO:0021508)
0.2	0.6	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.2	0.8	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.2	1.5	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.2	0.6	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.2	0.5	GO:0061072	iris morphogenesis(GO:0061072)
0.2	0.4	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.2	0.7	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.5	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.2	0.5	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.2	0.5	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.2	0.5	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.2	0.5	GO:0072205	metanephric collecting duct development(GO:0072205)
0.2	0.3	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.2	0.5	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.2	0.5	GO:0016081	synaptic vesicle docking(GO:0016081)
0.2	0.6	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.2	0.2	GO:0050923	Roundabout signaling pathway(GO:0035385) regulation of negative chemotaxis(GO:0050923)
0.2	0.6	GO:0070141	response to UV-A(GO:0070141)
0.2	0.3	GO:0060462	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.2	0.5	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2	0.6	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.4	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.6	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1	0.4	GO:0051451	myoblast migration(GO:0051451)
0.1	0.3	GO:0060083	urinary bladder smooth muscle contraction(GO:0014832) smooth muscle contraction involved in micturition(GO:0060083)
0.1	1.9	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.3	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.4	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	1.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	1.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.4	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.5	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.4	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	1.1	GO:0015732	prostaglandin transport(GO:0015732)
0.1	2.9	GO:0030199	collagen fibril organization(GO:0030199)
0.1	2.2	GO:0045987	positive regulation of smooth muscle contraction(GO:0045987)
0.1	0.4	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.4	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.1	GO:0072179	nephric duct formation(GO:0072179)
0.1	0.4	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.1	0.4	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.1	0.4	GO:0010842	retina layer formation(GO:0010842)
0.1	0.3	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.2	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.4	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.2	GO:0031223	response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.1	0.2	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) mesenchymal to epithelial transition(GO:0060231) renal vesicle morphogenesis(GO:0072077) metanephric renal vesicle morphogenesis(GO:0072283)
0.1	0.2	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.3	GO:0060992	response to fungicide(GO:0060992)
0.1	0.3	GO:0072070	loop of Henle development(GO:0072070)
0.1	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.5	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.1	0.3	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.3	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1	0.3	GO:0010659	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.5	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.4	GO:0060039	pericardium development(GO:0060039)
0.1	0.2	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1	0.2	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.3	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.7	GO:0015074	DNA integration(GO:0015074)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.2	GO:0022410	circadian sleep/wake cycle process(GO:0022410) circadian sleep/wake cycle, sleep(GO:0050802)
0.1	0.7	GO:0000052	citrulline metabolic process(GO:0000052)
0.1	1.0	GO:0030325	adrenal gland development(GO:0030325)
0.1	1.0	GO:0035329	hippo signaling(GO:0035329)
0.1	0.2	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.6	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.1	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.7	GO:0043113	receptor clustering(GO:0043113)
0.1	0.3	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.1	1.4	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.1	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.1	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.1	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.1	0.2	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.1	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.4	GO:0034331	cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.1	GO:0070254	mucus secretion(GO:0070254)
0.1	0.3	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.2	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.1	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.2	GO:0060437	lung growth(GO:0060437)
0.1	0.5	GO:0005513	detection of calcium ion(GO:0005513)
0.1	1.7	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.4	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.1	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.8	GO:0035411	catenin import into nucleus(GO:0035411) regulation of catenin import into nucleus(GO:0035412)
0.1	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.1	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.1	0.8	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.1	0.3	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.3	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.5	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.2	GO:0021984	adenohypophysis development(GO:0021984)
0.1	0.1	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1	0.5	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.1	0.1	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.7	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.1	0.1	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.1	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.1	GO:0001878	response to yeast(GO:0001878)
0.1	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.2	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.3	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.2	GO:0031034	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.2	GO:0021794	thalamus development(GO:0021794)
0.1	0.2	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.1	0.7	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.1	0.1	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.1	0.2	GO:0070091	glucagon secretion(GO:0070091)
0.1	1.2	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.1	0.1	GO:0043301	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.8	GO:0008038	neuron recognition(GO:0008038)
0.1	0.2	GO:0060033	anatomical structure regression(GO:0060033)
0.1	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.2	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.1	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.1	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.1	0.1	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.1	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.9	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.2	GO:0071436	sodium ion export(GO:0071436)
0.1	0.2	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.1	0.2	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.4	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.6	GO:0031114	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.7	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.0	GO:0045933	positive regulation of muscle contraction(GO:0045933)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.5	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.2	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.4	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.2	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.2	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.2	GO:0001964	startle response(GO:0001964)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0014048	regulation of glutamate secretion(GO:0014048)
0.0	0.1	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.0	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.3	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.3	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.0	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.9	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.5	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.2	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.3	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.0	0.2	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.0	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.2	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.6	GO:0007566	embryo implantation(GO:0007566)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.0	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.3	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.1	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.2	GO:0090102	cochlea development(GO:0090102)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.2	GO:0031000	response to caffeine(GO:0031000)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0	0.1	GO:2000258	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.2	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.5	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.1	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.1	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.2	GO:0001709	cell fate determination(GO:0001709)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.6	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.1	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0003151	outflow tract morphogenesis(GO:0003151)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.6	GO:0045762	positive regulation of adenylate cyclase activity(GO:0045762)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:1901888	regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) regulation of cell junction assembly(GO:1901888) regulation of adherens junction organization(GO:1903391)
0.0	0.4	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.7	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.7	GO:0042303	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0	0.3	GO:0048675	axon extension(GO:0048675) neuron projection extension(GO:1990138)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.5	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0002118	aggressive behavior(GO:0002118)
0.0	0.2	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0090303	positive regulation of wound healing(GO:0090303)
0.0	0.1	GO:0048339	paraxial mesoderm development(GO:0048339)
0.0	0.1	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.4	GO:1901343	negative regulation of vasculature development(GO:1901343)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.2	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.1	GO:0002027	regulation of heart rate(GO:0002027)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.2	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	2.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.4	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.2	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.2	GO:0009650	UV protection(GO:0009650)
0.0	0.2	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.0	GO:0043584	nose development(GO:0043584)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0021548	pons development(GO:0021548)
0.0	0.2	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.1	GO:0071398	cellular response to fatty acid(GO:0071398)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.0	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.0	0.4	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) vein smooth muscle contraction(GO:0014826) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0008595	blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0021879	forebrain neuron differentiation(GO:0021879)
0.0	0.0	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.0	GO:0032963	collagen metabolic process(GO:0032963)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.1	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0060296	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.0	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.1	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	1.2	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	3.3	GO:0007411	axon guidance(GO:0007411) neuron projection guidance(GO:0097485)
0.0	0.1	GO:0032373	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.1	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	1.2	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.6	GO:0001764	neuron migration(GO:0001764)
0.0	0.1	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.1	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.0	0.0	GO:0032106	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.0	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.4	GO:0048839	inner ear development(GO:0048839)
0.0	0.4	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.5	GO:0007588	excretion(GO:0007588)
0.0	1.9	GO:0006813	potassium ion transport(GO:0006813)
0.0	0.0	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.2	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.2	GO:0060070	canonical Wnt signaling pathway(GO:0060070)
0.0	0.1	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.0	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.0	GO:0007622	rhythmic behavior(GO:0007622)
0.0	0.0	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.0	GO:0015837	amine transport(GO:0015837)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0021517	ventral spinal cord development(GO:0021517)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.2	GO:0018904	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.0	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.1	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.3	GO:0017157	regulation of exocytosis(GO:0017157)
0.0	0.0	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.0	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.4	GO:0031668	cellular response to extracellular stimulus(GO:0031668)
0.0	0.0	GO:0031340	regulation of vesicle fusion(GO:0031338) positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0007492	endoderm development(GO:0007492)
0.0	0.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.0	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0060391	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0010657	muscle cell apoptotic process(GO:0010657) regulation of muscle cell apoptotic process(GO:0010660)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.0	GO:0030431	sleep(GO:0030431)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.1	GO:0031279	regulation of cyclase activity(GO:0031279)
0.0	0.0	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0006837	serotonin secretion(GO:0001820) serotonin transport(GO:0006837)
0.0	0.0	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0060192	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0005588	collagen type V trimer(GO:0005588)
0.4	2.1	GO:0010369	chromocenter(GO:0010369)
0.3	0.9	GO:0030934	anchoring collagen complex(GO:0030934)
0.3	0.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.7	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2	1.3	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2	1.4	GO:0098644	complex of collagen trimers(GO:0098644)
0.2	0.5	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	0.6	GO:0016600	flotillin complex(GO:0016600)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.4	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.1	0.6	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	0.8	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	0.4	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.4	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.7	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.7	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.7	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.6	GO:0001527	microfibril(GO:0001527)
0.1	0.6	GO:0030673	axolemma(GO:0030673)
0.1	0.5	GO:0031512	motile primary cilium(GO:0031512)
0.1	1.0	GO:0005581	collagen trimer(GO:0005581)
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.1	0.3	GO:0030904	retromer complex(GO:0030904)
0.1	0.8	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.8	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.1	GO:0016460	myosin II complex(GO:0016460)
0.1	0.3	GO:0005606	laminin-1 complex(GO:0005606)
0.1	1.3	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.4	GO:0031430	M band(GO:0031430)
0.1	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.5	GO:0042589	zymogen granule membrane(GO:0042589)
0.1	0.3	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.7	GO:0030315	T-tubule(GO:0030315)
0.1	14.8	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	2.7	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.3	GO:0005915	zonula adherens(GO:0005915)
0.1	0.3	GO:0071437	invadopodium(GO:0071437)
0.1	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	2.4	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	3.5	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.7	GO:0005902	microvillus(GO:0005902)
0.0	0.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	2.7	GO:0043025	neuronal cell body(GO:0043025)
0.0	1.0	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.6	GO:0030018	Z disc(GO:0030018)
0.0	0.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	1.0	GO:0043292	contractile fiber(GO:0043292)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	1.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	3.1	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.0	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.0	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.8	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.5	1.5	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.3	1.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	2.0	GO:0017154	semaphorin receptor activity(GO:0017154)
0.3	0.6	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	1.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.2	0.7	GO:0002162	dystroglycan binding(GO:0002162)
0.2	1.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	0.7	GO:0003680	AT DNA binding(GO:0003680)
0.2	0.7	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	1.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.2	0.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.8	GO:0048495	Roundabout binding(GO:0048495)
0.2	1.7	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.2	0.6	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.2	0.7	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.2	2.0	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2	1.3	GO:0008158	hedgehog receptor activity(GO:0008158)
0.2	0.8	GO:0070700	BMP receptor binding(GO:0070700)
0.2	0.5	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	0.5	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	1.3	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.6	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	1.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.7	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.6	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	0.6	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.4	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.4	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	2.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.5	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	0.9	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.5	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.9	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.8	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.3	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	7.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.3	GO:0070052	collagen V binding(GO:0070052)
0.1	0.3	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.3	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.4	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.3	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.3	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.8	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.8	GO:0004954	prostanoid receptor activity(GO:0004954)
0.1	0.3	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.3	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.3	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	1.7	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.9	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.4	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.3	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.2	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.4	GO:0016595	glutamate binding(GO:0016595)
0.1	0.7	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.1	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.7	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.2	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.1	0.3	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.3	GO:0005534	galactose binding(GO:0005534)
0.1	0.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.2	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.3	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.1	1.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.4	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.8	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.2	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	1.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	1.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	0.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.2	GO:0017166	vinculin binding(GO:0017166)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	1.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.4	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.2	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	1.0	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.3	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.4	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	2.2	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.3	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.3	GO:0005109	frizzled binding(GO:0005109)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.6	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.4	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.5	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	1.1	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.5	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.4	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.4	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.3	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.0	0.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	2.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0048406	neurotrophin binding(GO:0043121) nerve growth factor binding(GO:0048406)
0.0	0.4	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.3	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.5	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.9	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.7	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	1.1	GO:0008201	heparin binding(GO:0008201)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.3	GO:0017046	peptide hormone binding(GO:0017046)
0.0	1.6	GO:0008083	growth factor activity(GO:0008083)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.0	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0015149	hexose transmembrane transporter activity(GO:0015149)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	1.0	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.3	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.0	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.0	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.2	GO:0022839	ion gated channel activity(GO:0022839)
0.0	0.2	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	3.1	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.0	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.0	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0008483	transaminase activity(GO:0008483)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	7.0	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	2.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	1.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	3.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	1.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	3.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.1	1.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	2.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	2.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	0.6	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	0.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	7.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.9	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	PID FGF PATHWAY	FGF signaling pathway
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.2	PID BMP PATHWAY	BMP receptor signaling
0.0	6.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	1.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.4	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.0	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.3	PID LKB1 PATHWAY	LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	4.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	2.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2	8.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	0.9	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	1.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	1.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	2.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	0.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.1	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	1.3	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.1	0.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.7	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	2.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.0	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport

Results for EPAS1_BCL3

Z-value: 2.52

Motif logo

Transcription factors associated with EPAS1_BCL3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the EPAS1_BCL3 motif across conditions

Conditions sorted by the z-value of the EPAS1_BCL3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: