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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ESR1

Z-value: 0.83

Motif logo

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ESR1
ENSG00000091831.17 estrogen receptor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_152238268_152238543ESR1366130.2130690.674.8e-02Click!
chr6_152237063_152237214ESR1353460.2168860.636.9e-02Click!
chr6_152043262_152043413ESR1317060.208973-0.501.8e-01Click!
chr6_151990290_151990441ESR1212660.2226500.472.1e-01Click!
chr6_152126783_152127038ESR11020.9763070.452.2e-01Click!

Activity of the ESR1 motif across conditions

Conditions sorted by the z-value of the ESR1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_11323568_11323719 0.36 FAM167A
 family with sequence similarity 167, member A
 633
 0.67
chr13_114831006_114831265 0.32 RASA3
 RAS p21 protein activator 3
 12303
 0.24
chr20_18037263_18037961 0.28 OVOL2
 ovo-like zinc finger 2
 909
 0.48
chr3_49940788_49940939 0.27 MST1R
 macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
 179
 0.78
chr11_67078749_67078900 0.25 SSH3
 slingshot protein phosphatase 3
 3696
 0.13
chr1_153587674_153587825 0.25 S100A14
 S100 calcium binding protein A14
 665
 0.44
chr22_46482810_46483184 0.25 FLJ27365
 hsa-mir-4763
 1114
 0.31
chr7_45002030_45002849 0.25 RP4-647J21.1
1931
 0.25
chr14_105435453_105435767 0.25 AHNAK2
 AHNAK nucleoprotein 2
 9084
 0.16
chr9_110249313_110249729 0.24 KLF4
 Kruppel-like factor 4 (gut)
 1890
 0.38
chr8_10086913_10087064 0.24 MSRA
 methionine sulfoxide reductase A
 72057
 0.11
chr8_142289533_142290316 0.24 RP11-10J21.3
 Uncharacterized protein
 25260
 0.12
chr20_62168477_62168628 0.24 PTK6
 protein tyrosine kinase 6
 143
 0.91
chr9_140708937_140709088 0.23 ENSG00000207693
 .
 23859
 0.19
chr19_39227082_39227399 0.23 CAPN12
 calpain 12
 1178
 0.28
chr5_1931344_1931629 0.23 CTD-2194D22.4
44040
 0.13
chr14_24630498_24631577 0.22 IRF9
 interferon regulatory factor 9
 527
 0.47
chr14_91882732_91883366 0.22 CCDC88C
 coiled-coil domain containing 88C
 641
 0.78
chr19_41882652_41883217 0.22 TMEM91
 transmembrane protein 91
 60
 0.74
chr10_13143957_13144489 0.22 OPTN
 optineurin
 1998
 0.3
chr5_1315874_1316496 0.22 ENSG00000263670
 .
 6693
 0.18
chr22_20008729_20009650 0.22 TANGO2
 transport and golgi organization 2 homolog (Drosophila)
 511
 0.64
chr18_47089345_47089666 0.22 LIPG
 lipase, endothelial
 790
 0.6
chr1_36809017_36809168 0.22 STK40
 serine/threonine kinase 40
 17849
 0.12
chr1_6531968_6532119 0.22 TNFRSF25
 tumor necrosis factor receptor superfamily, member 25
 5788
 0.12
chr19_51455517_51455668 0.21 KLK5
 kallikrein-related peptidase 5
 606
 0.48
chr15_101774475_101774626 0.21 CHSY1
 chondroitin sulfate synthase 1
 17587
 0.17
chr19_8554749_8554900 0.21 HNRNPM
 heterogeneous nuclear ribonucleoprotein M
 3782
 0.14
chr17_48601050_48601201 0.21 MYCBPAP
 MYCBP associated protein
 44
 0.95
chr2_74668653_74669044 0.21 RTKN
 rhotekin
 178
 0.86
chr17_74868821_74868990 0.21 MGAT5B
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
 176
 0.95
chr14_100046170_100046321 0.21 CCDC85C
 coiled-coil domain containing 85C
 218
 0.93
chr19_2275585_2275736 0.21 OAZ1
 ornithine decarboxylase antizyme 1
 5370
 0.09
chr4_715290_715441 0.20 RP11-1191J2.4
2458
 0.16
chr4_1796827_1797107 0.20 FGFR3
 fibroblast growth factor receptor 3
 1344
 0.42
chr20_61733088_61733940 0.20 ENSG00000225978
 .
 31
 0.98
chr20_39970036_39970187 0.20 LPIN3
 lipin 3
 551
 0.77
chr17_7942417_7942568 0.20 ALOX15B
 arachidonate 15-lipoxygenase, type B
 18
 0.95
chr2_183225036_183225187 0.20 ENSG00000242121
 .
 46100
 0.17
chr1_3620270_3620421 0.20 TP73
 tumor protein p73
 5723
 0.12
chr1_26680354_26680505 0.20 AIM1L
 absent in melanoma 1-like
 192
 0.9
chr21_41095530_41095681 0.20 IGSF5
 immunoglobulin superfamily, member 5
 21729
 0.21
chr20_43970794_43971114 0.20 SDC4
 syndecan 4
 6110
 0.13
chr22_44568627_44569086 0.20 PARVG
 parvin, gamma
 20
 0.99
chr1_1015485_1015798 0.20 RNF223
 ring finger protein 223
 5954
 0.1
chr8_145012042_145012193 0.20 PLEC
 plectin
 1641
 0.24
chr8_144820927_144821078 0.20 FAM83H
 family with sequence similarity 83, member H
 5031
 0.09
chr22_46546744_46547896 0.19 PPARA
 peroxisome proliferator-activated receptor alpha
 467
 0.75
chr14_54430258_54430823 0.19 BMP4
 bone morphogenetic protein 4
 5061
 0.28
chr20_55204347_55205219 0.19 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
 425
 0.81
chr19_54057819_54058678 0.19 ZNF331
 zinc finger protein 331
 167
 0.9
chr3_5055440_5055591 0.19 BHLHE40-AS1
 BHLHE40 antisense RNA 1
 33869
 0.15
chr1_156092284_156092708 0.19 LMNA
 lamin A/C
 3455
 0.14
chr19_10406663_10406906 0.19 ICAM5
 intercellular adhesion molecule 5, telencephalin
 5131
 0.08
chr16_70740729_70741027 0.19 VAC14
 Vac14 homolog (S. cerevisiae)
 6730
 0.15
chr21_33247526_33247677 0.19 HUNK
 hormonally up-regulated Neu-associated kinase
 1973
 0.45
chr19_35608806_35608957 0.18 FXYD3
 FXYD domain containing ion transport regulator 3
 50
 0.95
chr12_67807670_67807821 0.18 CAND1
 cullin-associated and neddylation-dissociated 1
 114993
 0.07
chr17_76967334_76967485 0.18 LGALS3BP
 lectin, galactoside-binding, soluble, 3 binding protein
 5996
 0.16
chr18_74331565_74332218 0.18 LINC00908
 long intergenic non-protein coding RNA 908
 91017
 0.08
chr11_66829839_66829990 0.18 RHOD
 ras homolog family member D
 5554
 0.17
chr17_46127912_46128198 0.18 NFE2L1
 nuclear factor, erythroid 2-like 1
 1561
 0.2
chr1_1173779_1173930 0.18 B3GALT6
 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
 6225
 0.08
chr6_96455538_96455689 0.18 FUT9
 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
 8247
 0.33
chr11_70963000_70963203 0.18 SHANK2
 SH3 and multiple ankyrin repeat domains 2
 522
 0.86
chr16_31146277_31146629 0.18 PRSS8
 protease, serine, 8
 508
 0.52
chr14_35871775_35873043 0.18 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
 937
 0.68
chr11_1552591_1552742 0.18 DUSP8
 dual specificity phosphatase 8
 34500
 0.1
chr13_106939337_106939488 0.18 ENSG00000222682
 .
 131573
 0.05
chr9_139776272_139777152 0.18 TRAF2
 TNF receptor-associated factor 2
 327
 0.72
chr14_99710276_99710624 0.18 AL109767.1
18835
 0.2
chr3_10858354_10858505 0.18 SLC6A11
 solute carrier family 6 (neurotransmitter transporter), member 11
 543
 0.85
chr1_37943283_37943786 0.18 ZC3H12A
 zinc finger CCCH-type containing 12A
 3381
 0.18
chr2_232537261_232537412 0.17 ENSG00000239202
 .
 26352
 0.14
chr17_70114398_70114549 0.17 SOX9
 SRY (sex determining region Y)-box 9
 2688
 0.41
chr2_239036083_239036322 0.17 ESPNL
 espin-like
 166
 0.94
chr7_55253774_55253939 0.17 EGFR-AS1
 EGFR antisense RNA 1
 2771
 0.38
chr2_241949003_241950045 0.17 AC093585.6
637
 0.62
chr16_75416401_75416552 0.17 RP11-252K23.2
1318
 0.36
chr19_1469984_1470717 0.17 ENSG00000267317
 .
 7586
 0.07
chr9_134460250_134460544 0.17 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 36828
 0.13
chr2_239037206_239037357 0.17 ESPNL
 espin-like
 1245
 0.38
chr14_55035520_55036036 0.17 SAMD4A
 sterile alpha motif domain containing 4A
 1141
 0.56
chrX_48323916_48324124 0.17 SLC38A5
 solute carrier family 38, member 5
 1860
 0.23
chr1_21620629_21620823 0.17 ECE1
 endothelin converting enzyme 1
 191
 0.89
chr12_2403889_2404040 0.17 CACNA1C-IT3
 CACNA1C intronic transcript 3 (non-protein coding)
 25022
 0.23
chr3_52491643_52491832 0.17 NISCH
 nischarin
 2104
 0.18
chr7_1690037_1690188 0.17 ELFN1
 extracellular leucine-rich repeat and fibronectin type III domain containing 1
 37643
 0.14
chr6_41703786_41703937 0.17 TFEB
 transcription factor EB
 136
 0.93
chr8_144907347_144907498 0.17 PUF60
 poly-U binding splicing factor 60KDa
 3774
 0.11
chr19_34216636_34216787 0.17 CHST8
 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
 41277
 0.18
chr10_125852855_125853389 0.17 CHST15
 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
 84
 0.98
chr1_151579139_151579290 0.17 SNX27
 sorting nexin family member 27
 5344
 0.12
chr6_36098764_36099262 0.17 MAPK13
 mitogen-activated protein kinase 13
 573
 0.74
chr1_1978273_1978424 0.17 RP11-547D24.3
2742
 0.18
chr1_46955506_46955688 0.17 DMBX1
 diencephalon/mesencephalon homeobox 1
 17071
 0.16
chr4_1798938_1799089 0.17 FGFR3
 fibroblast growth factor receptor 3
 3390
 0.22
chr20_1309605_1309756 0.17 SDCBP2
 syndecan binding protein (syntenin) 2
 203
 0.91
chr20_39969728_39969901 0.17 LPIN3
 lipin 3
 254
 0.92
chr18_74798828_74799607 0.16 MBP
 myelin basic protein
 18000
 0.27
chr8_144302737_144302888 0.16 GPIHBP1
 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
 7744
 0.14
chr13_24270271_24270700 0.16 AL139080.1
 Uncharacterized protein
 51758
 0.14
chr5_2749613_2749799 0.16 IRX2
 iroquois homeobox 2
 2063
 0.35
chr11_61657871_61658132 0.16 FADS3
 fatty acid desaturase 3
 852
 0.49
chr1_55518873_55519024 0.16 PCSK9
 proprotein convertase subtilisin/kexin type 9
 13053
 0.2
chr19_54369142_54369556 0.16 MYADM
 myeloid-associated differentiation marker
 128
 0.89
chr19_13957589_13958095 0.16 ENSG00000207980
 .
 10369
 0.08
chr18_77938309_77938600 0.16 AC139100.3
3109
 0.25
chr16_85832192_85833030 0.16 COX4I1
 cytochrome c oxidase subunit IV isoform 1
 372
 0.56
chr8_10590631_10590782 0.16 SOX7
 SRY (sex determining region Y)-box 7
 2684
 0.21
chr1_16538998_16539149 0.16 ARHGEF19
 Rho guanine nucleotide exchange factor (GEF) 19
 31
 0.96
chr10_35060387_35060538 0.16 PARD3
 par-3 family cell polarity regulator
 43787
 0.16
chr8_145008502_145008738 0.16 PLEC
 plectin
 5138
 0.12
chr11_10695962_10696877 0.16 MRVI1
 murine retrovirus integration site 1 homolog
 18642
 0.17
chr10_73769586_73770005 0.16 CHST3
 carbohydrate (chondroitin 6) sulfotransferase 3
 45672
 0.15
chr1_185528978_185529129 0.16 ENSG00000207108
 .
 70607
 0.11
chr17_79378256_79378407 0.16 ENSG00000266392
 .
 3753
 0.14
chr19_11252844_11253247 0.16 SPC24
 SPC24, NDC80 kinetochore complex component
 13392
 0.13
chr3_133476385_133476536 0.16 TF
 transferrin
 11223
 0.18
chr4_3043146_3044167 0.16 ENSG00000199335
 .
 2172
 0.29
chr7_139047352_139047690 0.16 C7orf55-LUC7L2
 C7orf55-LUC7L2 readthrough
 2867
 0.19
chr20_45946936_45948261 0.16 AL031666.2
 HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
 352
 0.82
chr2_149895781_149895992 0.16 LYPD6B
 LY6/PLAUR domain containing 6B
 654
 0.82
chr10_29978497_29978648 0.15 ENSG00000222092
 .
 22272
 0.21
chr19_3387681_3387832 0.15 NFIC
 nuclear factor I/C (CCAAT-binding transcription factor)
 21172
 0.16
chr16_57653725_57653876 0.15 GPR56
 G protein-coupled receptor 56
 54
 0.97
chr4_17783377_17783652 0.15 FAM184B
 family with sequence similarity 184, member B
 379
 0.88
chr22_19792099_19792250 0.15 TBX1
 T-box 1
 47948
 0.1
chr8_22423482_22424350 0.15 SORBS3
 sorbin and SH3 domain containing 3
 402
 0.6
chr8_145698019_145698220 0.15 FOXH1
 forkhead box H1
 3599
 0.07
chr5_58055562_58056142 0.15 RP11-479O16.1
24754
 0.24
chr2_106886104_106886958 0.15 UXS1
 UDP-glucuronate decarboxylase 1
 75736
 0.1
chr19_13961881_13962048 0.15 ENSG00000207980
 .
 14491
 0.07
chr6_50817384_50817535 0.15 TFAP2B
 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
 31020
 0.25
chr8_128919529_128920109 0.15 TMEM75
 transmembrane protein 75
 40772
 0.15
chr22_40391518_40391669 0.15 FAM83F
 family with sequence similarity 83, member F
 640
 0.7
chr19_940940_941628 0.15 ARID3A
 AT rich interactive domain 3A (BRIGHT-like)
 8775
 0.08
chr6_160721267_160721418 0.15 SLC22A2
 solute carrier family 22 (organic cation transporter), member 2
 22672
 0.23
chr11_65360517_65360668 0.15 KCNK7
 potassium channel, subfamily K, member 7
 380
 0.52
chr1_34631906_34632332 0.15 C1orf94
 chromosome 1 open reading frame 94
 365
 0.8
chr17_15554007_15555167 0.15 RP11-640I15.1
317
 0.52
chr5_55839563_55839714 0.15 AC022431.3
5985
 0.25
chr12_125002282_125002834 0.15 NCOR2
 nuclear receptor corepressor 2
 282
 0.95
chr17_79779492_79779643 0.15 FAM195B
 family with sequence similarity 195, member B
 2796
 0.11
chr19_4061941_4062216 0.15 CTD-2622I13.3
669
 0.55
chr11_60609533_60610326 0.15 CCDC86
 coiled-coil domain containing 86
 385
 0.51
chr16_3014465_3014677 0.15 KREMEN2
 kringle containing transmembrane protein 2
 49
 0.93
chr1_41966637_41966788 0.15 EDN2
 endothelin 2
 16370
 0.19
chr1_12675825_12676469 0.15 DHRS3
 dehydrogenase/reductase (SDR family) member 3
 1590
 0.37
chr17_8218792_8218943 0.15 AC135178.7
3163
 0.11
chr19_49567989_49568490 0.15 NTF4
 neurotrophin 4
 72
 0.9
chr17_61513067_61513218 0.15 CYB561
 cytochrome b561
 597
 0.65
chr9_103791551_103791702 0.15 LPPR1
 Lipid phosphate phosphatase-related protein type 1
 635
 0.84
chr22_46959420_46959714 0.15 GRAMD4
 GRAM domain containing 4
 12342
 0.19
chr19_55658159_55658310 0.15 TNNT1
 troponin T type 1 (skeletal, slow)
 76
 0.93
chr14_105330590_105330952 0.15 CEP170B
 centrosomal protein 170B
 846
 0.6
chr11_6341290_6341712 0.15 PRKCDBP
 protein kinase C, delta binding protein
 261
 0.9
chr20_62573957_62574108 0.14 ENSG00000207554
 .
 47
 0.9
chr17_7492081_7492232 0.14 SOX15
 SRY (sex determining region Y)-box 15
 1234
 0.16
chr11_8299597_8299748 0.14 LMO1
 LIM domain only 1 (rhombotin 1)
 9409
 0.26
chr20_39945349_39946123 0.14 ZHX3
 zinc fingers and homeoboxes 3
 90
 0.97
chr5_150970622_150970773 0.14 FAT2
 FAT atypical cadherin 2
 22192
 0.17
chrX_153187182_153187333 0.14 ARHGAP4
 Rho GTPase activating protein 4
 369
 0.73
chr17_43249924_43250075 0.14 RP13-890H12.2
1048
 0.34
chr1_155097548_155097699 0.14 EFNA1
 ephrin-A1
 2313
 0.11
chr5_167243776_167243927 0.14 ENSG00000221741
 .
 53819
 0.13
chr8_145020311_145020609 0.14 PLEC
 plectin
 113
 0.91
chr19_3098811_3099227 0.14 GNA11
 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
 4611
 0.13
chr14_105564128_105564279 0.14 GPR132
 G protein-coupled receptor 132
 32421
 0.14
chr19_1749690_1749939 0.14 ONECUT3
 one cut homeobox 3
 2558
 0.2
chrX_11782921_11783072 0.14 MSL3
 male-specific lethal 3 homolog (Drosophila)
 5249
 0.33
chr6_12288567_12288718 0.14 EDN1
 endothelin 1
 1954
 0.48
chr17_79316804_79317024 0.14 TMEM105
 transmembrane protein 105
 12440
 0.13
chr1_156785806_156786457 0.14 SH2D2A
 SH2 domain containing 2A
 495
 0.51
chr13_114186665_114186816 0.14 TMCO3
 transmembrane and coiled-coil domains 3
 41382
 0.11
chr1_153507238_153508458 0.14 S100A6
 S100 calcium binding protein A6
 619
 0.48
chr1_6479504_6479655 0.14 HES2
 hes family bHLH transcription factor 2
 384
 0.76
chr11_1410043_1410900 0.14 BRSK2
 BR serine/threonine kinase 2
 658
 0.72
chr16_89427901_89428186 0.14 ANKRD11
 ankyrin repeat domain 11
 32649
 0.1
chr16_68824059_68824234 0.14 RP11-354M1.2
33283
 0.12
chr4_1761839_1761990 0.14 TACC3
 transforming, acidic coiled-coil containing protein 3
 31783
 0.12
chr1_230223344_230223516 0.14 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 20412
 0.23
chr2_120041666_120041961 0.14 STEAP3-AS1
 STEAP3 antisense RNA 1
 35166
 0.15
chr11_567710_568184 0.14 ENSG00000199038
 .
 251
 0.8
chr19_42440673_42440856 0.14 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 13518
 0.12
chr10_99331899_99332050 0.14 ANKRD2
 ankyrin repeat domain 2 (stretch responsive muscle)
 224
 0.89
chr8_142083960_142084111 0.14 DENND3
 DENN/MADD domain containing 3
 43342
 0.14
chr17_78866297_78866787 0.14 RPTOR
 regulatory associated protein of MTOR, complex 1
 29982
 0.14
chr19_13110560_13110829 0.14 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 4042
 0.11
chr11_3876946_3878257 0.14 STIM1
 stromal interaction molecule 1
 189
 0.59
chr15_31757911_31758062 0.14 KLF13
 Kruppel-like factor 13
 99629
 0.08
chr17_7256192_7256343 0.14 KCTD11
 potassium channel tetramerization domain containing 11
 1059
 0.2
chr6_108141455_108142294 0.14 SCML4
 sex comb on midleg-like 4 (Drosophila)
 3642
 0.33
chr7_73021530_73021732 0.14 MLXIPL
 MLX interacting protein-like
 8860
 0.14
chr2_128395783_128395934 0.14 LIMS2
 LIM and senescent cell antigen-like domains 2
 3848
 0.17
chr17_38656484_38656635 0.14 TNS4
 tensin 4
 1290
 0.42
chr1_38513049_38513583 0.14 POU3F1
 POU class 3 homeobox 1
 866
 0.54
chr9_131126990_131127303 0.14 URM1
 ubiquitin related modifier 1
 6452
 0.1
chr10_8076986_8077137 0.14 GATA3
 GATA binding protein 3
 19595
 0.29
chr13_30168298_30169638 0.14 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 857
 0.74

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.3 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.1 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.2 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.1 0.2 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.1 0.2 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.1 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.3 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.1 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605) regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.2 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.1 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.2 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:0003323 type B pancreatic cell development(GO:0003323)
0.1 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.2 GO:0070977 organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0 0.2 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.3 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.2 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.0 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0060462 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.2 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0051590 positive regulation of neurotransmitter transport(GO:0051590)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859) establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0061339 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.2 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0051608 histamine transport(GO:0051608)
0.0 0.2 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.0 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.0 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
0.0 0.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0031943 regulation of glucocorticoid metabolic process(GO:0031943)
0.0 0.2 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0061043 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.0 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0001839 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0 0.1 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.2 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0 0.2 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0090281 negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.1 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0010984 regulation of lipoprotein particle clearance(GO:0010984)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0032610 interleukin-1 alpha production(GO:0032610)
0.0 0.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0090494 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.0 GO:0055026 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.0 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:1901862 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0046958 nonassociative learning(GO:0046958)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.0 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.0 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.2 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0030850 prostate gland development(GO:0030850)
0.0 0.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0042634 regulation of hair cycle(GO:0042634)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.0 GO:0090103 cochlea morphogenesis(GO:0090103)
0.0 0.0 GO:0002363 alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
0.0 0.1 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.0 GO:0010543 regulation of platelet activation(GO:0010543)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.0 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101) citrulline biosynthetic process(GO:0019240)
0.0 0.0 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.0 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.0 0.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.0 GO:0002830 positive regulation of type 2 immune response(GO:0002830)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.0 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.0 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.0 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.0 GO:0032971 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.7 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.0 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.2 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.0 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.0 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0008378 galactosyltransferase activity(GO:0008378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME NEUROTRANSMITTER RELEASE CYCLE Genes involved in Neurotransmitter Release Cycle
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions