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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for ESRRA_ESR2

Z-value: 3.74

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Transcription factors associated with ESRRA_ESR2

Gene Symbol	Gene ID	Gene Info
ESRRA Ensembl NCBI GeneCards UniProt	ENSG00000173153.9	estrogen related receptor alpha
ESR2 Ensembl NCBI GeneCards UniProt	ENSG00000140009.14	estrogen receptor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr14_64720582_64720733	ESR2	29046	0.171076	-0.62	7.5e-02	Click!
chr14_64759811_64759962	ESR2	1192	0.516523	-0.52	1.5e-01	Click!
chr14_64720750_64720901	ESR2	28878	0.171524	-0.43	2.5e-01	Click!
chr14_64804508_64805275	ESR2	61	0.865505	0.14	7.2e-01	Click!
chr14_64804121_64804291	ESR2	608	0.556640	-0.14	7.2e-01	Click!
chr11_64071742_64071893	ESRRA	1227	0.196322	0.64	6.1e-02	Click!
chr11_64071910_64072476	ESRRA	851	0.304076	0.62	7.4e-02	Click!
chr11_64081738_64081889	ESRRA	57	0.916906	-0.59	9.8e-02	Click!
chr11_64073389_64074392	ESRRA	28	0.924495	0.55	1.3e-01	Click!
chr11_64074500_64074651	ESRRA	657	0.408482	0.51	1.6e-01	Click!

Activity of the ESRRA_ESR2 motif across conditions

Conditions sorted by the z-value of the ESRRA_ESR2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_95727852_95728104	3.04	FGD3	FYVE, RhoGEF and PH domain containing 3	1735	0.41
chr1_161038546_161039545	2.93	ARHGAP30	Rho GTPase activating protein 30	411	0.65
chr13_113622985_113623455	2.79	MCF2L-AS1	MCF2L antisense RNA 1	82	0.79
chr1_26872331_26872899	2.68	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	272	0.88
chr14_93118654_93119048	2.63	RIN3	Ras and Rab interactor 3	5	0.99
chr17_7239932_7240900	2.52	ACAP1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	507	0.51
chr17_56410108_56410593	2.40	MIR142	microRNA 142	481	0.66
chr17_265803_266293	2.26	AC108004.3		2234	0.23
chr9_95822109_95822464	2.21	SUSD3	sushi domain containing 3	1225	0.45
chr12_51717169_51717830	2.20	BIN2	bridging integrator 2	400	0.82
chr7_38389675_38390189	2.19	AMPH	amphiphysin	112781	0.07
chr11_118094529_118095128	2.17	AMICA1	adhesion molecule, interacts with CXADR antigen 1	26	0.97
chr12_58135257_58135844	2.12	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	390	0.63
chr11_104904746_104905919	2.11	CASP1	caspase 1, apoptosis-related cysteine peptidase	508	0.77
chr17_73840046_73840332	2.10	UNC13D	unc-13 homolog D (C. elegans)	226	0.84
chr19_6481304_6482171	2.09	DENND1C	DENN/MADD domain containing 1C	27	0.95
chr16_30484007_30484505	2.07	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	184	0.81
chr19_3136242_3137376	2.02	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	618	0.58
chr8_134079225_134079805	2.02	SLA	Src-like-adaptor	6912	0.26
chr11_65408534_65408946	1.97	SIPA1	signal-induced proliferation-associated 1	441	0.63
chr2_85804717_85805457	1.93	VAMP8	vesicle-associated membrane protein 8	371	0.72
chr19_1068246_1068401	1.92	HMHA1	histocompatibility (minor) HA-1	826	0.4
chr9_134127628_134128133	1.90	FAM78A	family with sequence similarity 78, member A	18000	0.15
chr11_65184608_65185159	1.88	ENSG00000245532	.	27046	0.09
chr19_1258842_1259341	1.88	CIRBP	cold inducible RNA binding protein	293	0.78
chr11_121324494_121324645	1.88	RP11-730K11.1		847	0.59
chr19_54881402_54882266	1.87	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	224	0.88
chr19_952910_953260	1.86	ARID3A	AT rich interactive domain 3A (BRIGHT-like)	20576	0.07
chr5_176785343_176785607	1.85	RGS14	regulator of G-protein signaling 14	637	0.54
chr19_7413904_7414409	1.83	CTB-133G6.1		308	0.88
chr19_14551433_14551660	1.83	PKN1	protein kinase N1	474	0.7
chr19_4916483_4916936	1.81	ARRDC5	arrestin domain containing 5	13830	0.12
chr20_62369505_62369786	1.80	RP4-583P15.14		22	0.92
chr1_9690042_9690512	1.77	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	21513	0.15
chr12_122225090_122225354	1.76	RHOF	ras homolog family member F (in filopodia)	6044	0.17
chr7_38398847_38399253	1.76	AMPH	amphiphysin	103663	0.08
chr14_100531999_100532513	1.75	EVL	Enah/Vasp-like	498	0.76
chr11_280700_281222	1.74	NLRP6	NLR family, pyrin domain containing 6	2391	0.12
chr20_62271176_62271486	1.74	CTD-3184A7.4		12728	0.09
chr20_56193926_56194226	1.74	ZBP1	Z-DNA binding protein 1	1374	0.49
chr1_111745814_111746254	1.73	DENND2D	DENN/MADD domain containing 2D	997	0.41
chr21_46340531_46340791	1.71	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	109	0.73
chr19_39108076_39108634	1.69	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	209	0.87
chr5_169724277_169724686	1.69	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	750	0.71
chr19_16254556_16255035	1.68	HSH2D	hematopoietic SH2 domain containing	249	0.88
chr1_154981512_154981710	1.68	ZBTB7B	zinc finger and BTB domain containing 7B	5313	0.08
chr15_77287809_77288285	1.67	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	132	0.96
chr7_150264558_150265605	1.67	GIMAP4	GTPase, IMAP family member 4	557	0.78
chr11_82828119_82828301	1.66	PCF11	PCF11 cleavage and polyadenylation factor subunit	39820	0.12
chr20_4795670_4795862	1.65	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	3	0.98
chr2_240187102_240187645	1.64	ENSG00000265215	.	39784	0.13
chr19_10449910_10450285	1.62	ICAM3	intercellular adhesion molecule 3	198	0.86
chr22_40858929_40859404	1.57	MKL1	megakaryoblastic leukemia (translocation) 1	256	0.92
chr17_56408975_56409725	1.56	MIR142	microRNA 142	519	0.63
chr7_157405294_157405606	1.55	AC005481.5	Uncharacterized protein	1265	0.52
chr9_134150778_134151758	1.55	FAM78A	family with sequence similarity 78, member A	666	0.69
chr11_46367119_46367443	1.54	DGKZ	diacylglycerol kinase, zeta	294	0.88
chr14_76009252_76009829	1.53	BATF	basic leucine zipper transcription factor, ATF-like	20637	0.15
chr15_75081452_75081829	1.53	ENSG00000264386	.	542	0.49
chr6_167369037_167370142	1.52	RP11-514O12.4		23	0.9
chr7_73624740_73625015	1.52	LAT2	linker for activation of T cells family, member 2	524	0.74
chr19_42705324_42705475	1.51	ENSG00000265122	.	8169	0.09
chr11_65185943_65186437	1.51	ENSG00000245532	.	25739	0.09
chr17_76123369_76123520	1.51	TMC6	transmembrane channel-like 6	343	0.8
chr12_25207113_25207806	1.50	LRMP	lymphoid-restricted membrane protein	1785	0.37
chr11_47416652_47416817	1.50	RP11-750H9.5		457	0.65
chr11_104914891_104915295	1.50	CARD16	caspase recruitment domain family, member 16	941	0.54
chr11_47380887_47381038	1.49	MYBPC3	myosin binding protein C, cardiac	6709	0.11
chr11_46367528_46367907	1.49	DGKZ	diacylglycerol kinase, zeta	730	0.6
chr11_1874347_1875032	1.47	LSP1	lymphocyte-specific protein 1	489	0.65
chr19_49838375_49839003	1.47	CD37	CD37 molecule	5	0.95
chr17_43301591_43301923	1.47	CTD-2020K17.1		2168	0.16
chr1_32718292_32718517	1.46	LCK	lymphocyte-specific protein tyrosine kinase	1529	0.2
chr22_37680309_37680627	1.46	CYTH4	cytohesin 4	1940	0.3
chr2_231090336_231091061	1.46	SP140	SP140 nuclear body protein	219	0.54
chr12_117536177_117536841	1.45	TESC	tescalcin	742	0.76
chr19_3179462_3180177	1.44	S1PR4	sphingosine-1-phosphate receptor 4	1083	0.38
chr7_45016674_45016991	1.44	MYO1G	myosin IG	1865	0.25
chr7_150148744_150149359	1.43	GIMAP8	GTPase, IMAP family member 8	1333	0.41
chrX_48542477_48542733	1.43	WAS	Wiskott-Aldrich syndrome	437	0.75
chr15_81586633_81587120	1.42	IL16	interleukin 16	2378	0.31
chr9_139427949_139428157	1.42	RP11-413M3.4		9280	0.09
chr19_2290395_2291381	1.39	LINGO3	leucine rich repeat and Ig domain containing 3	1135	0.28
chr16_50714281_50714981	1.39	SNX20	sorting nexin 20	592	0.64
chr22_44577668_44577918	1.38	PARVG	parvin, gamma	52	0.99
chr20_47437784_47438180	1.38	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	6438	0.29
chr1_12230241_12230523	1.38	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	3322	0.2
chr12_4381475_4382675	1.38	CCND2	cyclin D2	863	0.52
chr7_128579388_128579603	1.38	IRF5	interferon regulatory factor 5	765	0.6
chr11_67172347_67172531	1.38	TBC1D10C	TBC1 domain family, member 10C	779	0.35
chr6_30798000_30798388	1.37	ENSG00000202241	.	33833	0.07
chrX_48772131_48772362	1.36	PIM2	pim-2 oncogene	766	0.45
chr15_52023462_52024365	1.36	LYSMD2	LysM, putative peptidoglycan-binding, domain containing 2	6405	0.15
chr10_135088849_135089035	1.36	ADAM8	ADAM metallopeptidase domain 8	1412	0.25
chr18_77283391_77284187	1.36	AC018445.1	Uncharacterized protein	7732	0.29
chr5_150602561_150602806	1.36	CCDC69	coiled-coil domain containing 69	1023	0.53
chr16_30106167_30106460	1.36	YPEL3	yippee-like 3 (Drosophila)	1020	0.25
chr22_37545294_37545803	1.35	IL2RB	interleukin 2 receptor, beta	482	0.7
chr16_28996496_28996848	1.34	LAT	linker for activation of T cells	11	0.94
chr10_134260489_134261029	1.34	C10orf91	chromosome 10 open reading frame 91	2066	0.3
chr14_99734743_99735157	1.34	BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	2615	0.3
chr1_202129278_202129681	1.34	PTPN7	protein tyrosine phosphatase, non-receptor type 7	251	0.89
chr13_114831006_114831265	1.34	RASA3	RAS p21 protein activator 3	12303	0.24
chr2_204801338_204802214	1.33	ICOS	inducible T-cell co-stimulator	273	0.95
chr9_134149437_134149588	1.33	FAM78A	family with sequence similarity 78, member A	2422	0.27
chr16_50308522_50308701	1.32	ADCY7	adenylate cyclase 7	547	0.79
chr9_139923413_139923722	1.32	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2	827	0.27
chr17_43487096_43487739	1.32	ARHGAP27	Rho GTPase activating protein 27	335	0.82
chr10_26727488_26728306	1.31	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	543	0.85
chr22_44391651_44392034	1.30	PARVB	parvin, beta	3249	0.27
chr1_209930701_209930998	1.30	TRAF3IP3	TRAF3 interacting protein 3	994	0.46
chr19_36398415_36398818	1.30	TYROBP	TYRO protein tyrosine kinase binding protein	533	0.58
chr21_43483378_43483554	1.29	UMODL1	uromodulin-like 1	398	0.86
chr12_7061050_7061251	1.29	PTPN6	protein tyrosine phosphatase, non-receptor type 6	612	0.41
chr8_142255255_142255924	1.29	RP11-10J21.4		7802	0.15
chr17_72733506_72734386	1.29	RAB37	RAB37, member RAS oncogene family	575	0.59
chr21_35304396_35305066	1.28	LINC00649	long intergenic non-protein coding RNA 649	1213	0.41
chr12_53600321_53600967	1.28	ITGB7	integrin, beta 7	356	0.78
chr17_61779840_61780056	1.28	LIMD2	LIM domain containing 2	1416	0.31
chr6_35270264_35270539	1.27	DEF6	differentially expressed in FDCP 6 homolog (mouse)	4772	0.2
chr1_151028880_151029472	1.27	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	1058	0.29
chr12_4385782_4386106	1.27	CCND2-AS1	CCND2 antisense RNA 1	594	0.46
chr9_95727201_95727619	1.27	FGD3	FYVE, RhoGEF and PH domain containing 3	1167	0.54
chr1_39680841_39681106	1.27	RP11-416A14.1		8789	0.18
chr21_46339892_46340194	1.26	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	727	0.4
chr3_176919226_176919959	1.26	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	4331	0.31
chr20_62709494_62709725	1.26	RGS19	regulator of G-protein signaling 19	1236	0.25
chrX_128920138_128920289	1.26	SASH3	SAM and SH3 domain containing 3	6253	0.21
chr4_2802491_2802761	1.26	SH3BP2	SH3-domain binding protein 2	1901	0.35
chr1_203242727_203243151	1.26	BTG2	BTG family, member 2	31725	0.13
chr14_105527312_105527781	1.25	GPR132	G protein-coupled receptor 132	3727	0.23
chr8_142105442_142105593	1.25	DENND3	DENN/MADD domain containing 3	21860	0.19
chr5_175085682_175085863	1.25	HRH2	histamine receptor H2	739	0.7
chr11_64642207_64642476	1.25	EHD1	EH-domain containing 1	797	0.45
chr9_130666481_130666789	1.25	ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	974	0.33
chr17_56413846_56414087	1.24	ENSG00000264399	.	583	0.4
chr14_23588365_23588516	1.23	CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon	385	0.75
chr22_37637944_37638095	1.23	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	2269	0.23
chr2_202098499_202098878	1.23	CASP8	caspase 8, apoptosis-related cysteine peptidase	459	0.82
chr17_76255043_76255413	1.23	TMEM235	transmembrane protein 235	27106	0.12
chr5_176786759_176786924	1.23	RGS14	regulator of G-protein signaling 14	2003	0.18
chr3_5019013_5019527	1.23	BHLHE40	basic helix-loop-helix family, member e40	1531	0.38
chr17_38483011_38483310	1.23	RARA	retinoic acid receptor, alpha	8623	0.11
chr1_202130035_202130186	1.22	PTPN7	protein tyrosine phosphatase, non-receptor type 7	338	0.84
chr15_81590554_81590826	1.22	IL16	interleukin 16	1067	0.54
chr3_183273082_183273407	1.21	KLHL6	kelch-like family member 6	233	0.92
chr1_198611164_198611406	1.21	PTPRC	protein tyrosine phosphatase, receptor type, C	2993	0.32
chr14_22988565_22988896	1.21	TRAJ15	T cell receptor alpha joining 15	9850	0.11
chr11_67173386_67173537	1.21	TBC1D10C	TBC1 domain family, member 10C	1801	0.14
chr16_745762_746190	1.20	FBXL16	F-box and leucine-rich repeat protein 16	49	0.9
chr20_62369822_62370052	1.20	RP4-583P15.14		314	0.7
chr18_60193065_60194045	1.20	ZCCHC2	zinc finger, CCHC domain containing 2	2703	0.37
chr7_45017874_45018185	1.19	MYO1G	myosin IG	668	0.61
chrX_78620994_78621299	1.19	ITM2A	integral membrane protein 2A	1710	0.55
chr1_198612556_198613143	1.19	PTPRC	protein tyrosine phosphatase, receptor type, C	4557	0.28
chr17_43300498_43300952	1.19	CTD-2020K17.1		1136	0.27
chr19_13206703_13207270	1.19	LYL1	lymphoblastic leukemia derived sequence 1	6695	0.11
chr4_90228457_90229530	1.18	GPRIN3	GPRIN family member 3	168	0.97
chr16_745521_745735	1.18	FBXL16	F-box and leucine-rich repeat protein 16	397	0.57
chr15_31623610_31623861	1.18	KLF13	Kruppel-like factor 13	4677	0.34
chr7_50349443_50349694	1.18	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1250	0.61
chr14_74211134_74211285	1.18	ELMSAN1	ELM2 and Myb/SANT-like domain containing 1	4251	0.14
chr11_3876946_3878257	1.17	STIM1	stromal interaction molecule 1	189	0.59
chr12_122230087_122230336	1.17	RHOF	ras homolog family member F (in filopodia)	1055	0.48
chr17_33640471_33640814	1.17	SLFN11	schlafen family member 11	39508	0.12
chr5_150593652_150593827	1.17	GM2A	GM2 ganglioside activator	2028	0.31
chr8_134086172_134086360	1.17	SLA	Src-like-adaptor	13663	0.23
chr16_23847524_23848074	1.17	PRKCB	protein kinase C, beta	396	0.89
chr6_36098764_36099262	1.17	MAPK13	mitogen-activated protein kinase 13	573	0.74
chr4_8200922_8201607	1.16	SH3TC1	SH3 domain and tetratricopeptide repeats 1	166	0.96
chr19_13212467_13212618	1.16	LYL1	lymphoblastic leukemia derived sequence 1	1139	0.32
chr2_233946751_233946902	1.16	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	21637	0.18
chr12_111866407_111866581	1.15	SH2B3	SH2B adaptor protein 3	6172	0.2
chr3_47023261_47023739	1.15	CCDC12	coiled-coil domain containing 12	28	0.97
chr1_160548800_160549253	1.15	CD84	CD84 molecule	237	0.91
chr4_40202563_40202865	1.15	RHOH	ras homolog family member H	750	0.7
chr4_2813731_2813882	1.14	SH3BP2	SH3-domain binding protein 2	140	0.96
chr9_130539368_130539592	1.14	SH2D3C	SH2 domain containing 3C	1540	0.21
chr7_137620698_137620944	1.14	CREB3L2	cAMP responsive element binding protein 3-like 2	2185	0.34
chr1_198632521_198632794	1.14	RP11-553K8.5		3533	0.3
chr7_2568940_2569293	1.14	ENSG00000264357	.	2408	0.22
chr17_4384641_4384911	1.13	RP13-580F15.2		2103	0.23
chrX_129225814_129226276	1.13	ELF4	E74-like factor 4 (ets domain transcription factor)	18291	0.19
chr11_6766362_6766695	1.13	GVINP1	GTPase, very large interferon inducible pseudogene 1	23417	0.11
chr22_37258145_37258296	1.13	NCF4	neutrophil cytosolic factor 4, 40kDa	1190	0.38
chr19_39368986_39369494	1.13	RINL	Ras and Rab interactor-like	321	0.74
chr1_26316819_26316970	1.12	PAFAH2	platelet-activating factor acetylhydrolase 2, 40kDa	7218	0.1
chr2_198172097_198172605	1.12	ANKRD44	ankyrin repeat domain 44	3160	0.2
chr1_40849833_40850457	1.12	SMAP2	small ArfGAP2	9825	0.18
chrX_106958420_106958715	1.12	TSC22D3	TSC22 domain family, member 3	1064	0.59
chr21_45773621_45773812	1.12	TRPM2	transient receptor potential cation channel, subfamily M, member 2	145	0.91
chr11_121330361_121330648	1.12	RP11-730K11.1		6782	0.25
chr14_100533458_100533776	1.11	EVL	Enah/Vasp-like	843	0.55
chr19_42705548_42705699	1.11	ENSG00000265122	.	8393	0.09
chr8_134071502_134071774	1.11	SLA	Src-like-adaptor	965	0.65
chr9_117134390_117135168	1.11	AKNA	AT-hook transcription factor	4465	0.23
chrX_153190817_153191535	1.10	ARHGAP4	Rho GTPase activating protein 4	522	0.6
chr6_20206247_20206398	1.10	RP11-239H6.2		5996	0.24
chr7_151046647_151046863	1.10	NUB1	negative regulator of ubiquitin-like proteins 1	4324	0.18
chr20_50158730_50159057	1.10	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	365	0.92

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRA_ESR2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	1.8	GO:0061154	endothelial tube morphogenesis(GO:0061154)
1.6	4.7	GO:0035405	histone-threonine phosphorylation(GO:0035405)
1.4	8.3	GO:0045588	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
1.3	3.8	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
1.3	1.3	GO:0046645	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
1.2	4.6	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
1.1	4.6	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
1.1	3.4	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
1.0	3.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
1.0	3.0	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
1.0	3.0	GO:0030223	neutrophil differentiation(GO:0030223)
1.0	2.9	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.9	4.7	GO:0045059	positive thymic T cell selection(GO:0045059)
0.9	0.9	GO:0032729	positive regulation of interferon-gamma production(GO:0032729)
0.9	1.7	GO:0033622	integrin activation(GO:0033622)
0.8	1.7	GO:0045630	positive regulation of type 2 immune response(GO:0002830) positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.8	6.6	GO:0007172	signal complex assembly(GO:0007172)
0.8	0.8	GO:0002448	mast cell mediated immunity(GO:0002448)
0.8	4.7	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.8	3.9	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.8	3.1	GO:0034063	stress granule assembly(GO:0034063)
0.8	6.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.8	3.8	GO:0007386	compartment pattern specification(GO:0007386)
0.7	2.2	GO:0045056	transcytosis(GO:0045056)
0.7	2.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.7	2.6	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.6	1.3	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.6	1.9	GO:0015809	arginine transport(GO:0015809)
0.6	1.3	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.6	2.5	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.6	1.9	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.6	2.5	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.6	0.6	GO:0002544	chronic inflammatory response(GO:0002544)
0.6	1.8	GO:0019372	lipoxygenase pathway(GO:0019372)
0.6	3.0	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.6	1.8	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.6	2.4	GO:0070670	response to interleukin-4(GO:0070670)
0.6	1.2	GO:0002524	hypersensitivity(GO:0002524) regulation of acute inflammatory response to antigenic stimulus(GO:0002864) regulation of hypersensitivity(GO:0002883)
0.6	0.6	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.6	1.8	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.6	0.6	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.6	2.3	GO:0003093	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.6	2.3	GO:0001787	natural killer cell proliferation(GO:0001787)
0.6	2.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.6	1.7	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.6	0.6	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.5	0.5	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.5	1.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.5	1.1	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5	1.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.5	3.2	GO:0043368	positive T cell selection(GO:0043368)
0.5	11.7	GO:0045576	mast cell activation(GO:0045576)
0.5	2.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.5	1.5	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.5	2.6	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.5	1.0	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678) positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.5	3.0	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.5	3.0	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.5	8.5	GO:0046834	lipid phosphorylation(GO:0046834)
0.5	1.0	GO:0032898	neurotrophin production(GO:0032898)
0.5	1.5	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.5	1.5	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.5	1.5	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.5	3.4	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.5	2.4	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.5	1.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.5	0.9	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.5	0.5	GO:0070265	necrotic cell death(GO:0070265)
0.5	0.9	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.5	2.3	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.5	0.9	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.5	1.8	GO:0050685	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.5	1.8	GO:0019388	galactose catabolic process(GO:0019388)
0.5	0.9	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.5	0.5	GO:0051023	immunoglobulin secretion(GO:0048305) regulation of immunoglobulin secretion(GO:0051023)
0.4	0.4	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.4	0.4	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.4	2.6	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.4	1.3	GO:0035455	response to interferon-alpha(GO:0035455)
0.4	1.3	GO:0006154	adenosine catabolic process(GO:0006154)
0.4	1.7	GO:0010508	positive regulation of autophagy(GO:0010508)
0.4	1.3	GO:0000212	meiotic spindle organization(GO:0000212)
0.4	1.7	GO:0018101	protein citrullination(GO:0018101)
0.4	1.3	GO:0000089	mitotic metaphase(GO:0000089)
0.4	1.3	GO:0043276	anoikis(GO:0043276)
0.4	1.3	GO:0001782	B cell homeostasis(GO:0001782)
0.4	4.2	GO:0090200	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.4	1.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.4	1.2	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.4	0.8	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.4	0.4	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.4	1.2	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.4	1.6	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.4	0.4	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.4	1.2	GO:0048143	astrocyte activation(GO:0048143)
0.4	1.6	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.4	1.2	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.4	1.2	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.4	0.4	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.4	1.2	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.4	1.2	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.4	0.4	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.4	1.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.4	2.7	GO:0036230	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.4	0.4	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.4	3.9	GO:0045730	respiratory burst(GO:0045730)
0.4	0.8	GO:0032743	positive regulation of interleukin-2 production(GO:0032743)
0.4	0.4	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.4	3.5	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.4	1.5	GO:2000193	positive regulation of fatty acid transport(GO:2000193)
0.4	1.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.4	2.7	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.4	1.9	GO:0042989	sequestering of actin monomers(GO:0042989)
0.4	1.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.4	0.4	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.4	3.0	GO:0006491	N-glycan processing(GO:0006491)
0.4	16.7	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.4	1.9	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.4	1.8	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.4	2.2	GO:0050798	activated T cell proliferation(GO:0050798)
0.4	0.4	GO:0009267	cellular response to starvation(GO:0009267)
0.4	0.4	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4	1.4	GO:0019322	pentose biosynthetic process(GO:0019322)
0.4	5.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.3	1.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.3	0.3	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.3	5.8	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3	16.0	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.3	0.7	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.3	2.0	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.3	0.6	GO:0040016	embryonic cleavage(GO:0040016)
0.3	0.3	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.3	0.3	GO:0016572	histone phosphorylation(GO:0016572)
0.3	0.3	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.3	1.6	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.3	3.2	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
0.3	1.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.3	4.8	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.3	0.9	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.3	0.6	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.3	4.7	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.3	0.9	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.3	1.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.3	1.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.3	0.3	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.3	1.8	GO:0006265	DNA topological change(GO:0006265)
0.3	0.6	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.3	1.5	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.3	1.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3	0.6	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.3	12.0	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
0.3	1.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.3	3.0	GO:0031648	protein destabilization(GO:0031648)
0.3	1.8	GO:0032613	interleukin-10 production(GO:0032613)
0.3	5.9	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.3	1.2	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.3	0.9	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.3	0.6	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.3	4.9	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.3	0.9	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.3	3.5	GO:0009595	detection of biotic stimulus(GO:0009595)
0.3	1.7	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.3	0.9	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.3	1.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.3	5.4	GO:0006611	protein export from nucleus(GO:0006611)
0.3	0.6	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.3	2.8	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.3	0.8	GO:0015801	aromatic amino acid transport(GO:0015801)
0.3	2.5	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.3	1.4	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.3	1.1	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.3	0.8	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.3	0.5	GO:1902339	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3	0.8	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.3	4.6	GO:0007032	endosome organization(GO:0007032)
0.3	0.8	GO:0001955	blood vessel maturation(GO:0001955)
0.3	1.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.3	0.8	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.3	0.8	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.3	1.3	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.3	1.1	GO:0042116	macrophage activation(GO:0042116)
0.3	1.3	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.3	0.5	GO:0001820	serotonin secretion(GO:0001820)
0.3	0.5	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.3	1.9	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.3	1.9	GO:0045116	protein neddylation(GO:0045116)
0.3	0.5	GO:0048535	lymph node development(GO:0048535)
0.3	1.1	GO:0044117	growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) negative regulation of growth of symbiont in host(GO:0044130) modulation of growth of symbiont involved in interaction with host(GO:0044144) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.3	0.8	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.3	2.4	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.3	0.5	GO:0006089	lactate metabolic process(GO:0006089)
0.3	0.5	GO:0022417	protein maturation by protein folding(GO:0022417)
0.3	0.5	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.3	0.8	GO:0015825	L-serine transport(GO:0015825)
0.3	0.3	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.3	0.5	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.3	0.5	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.3	0.8	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3	0.3	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.3	0.8	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.3	0.8	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3	1.5	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.3	1.0	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.3	0.3	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.3	1.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.3	0.3	GO:0044764	multi-organism cellular process(GO:0044764)
0.2	1.0	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.2	0.7	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.2	1.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.2	0.7	GO:0032203	telomere formation via telomerase(GO:0032203)
0.2	0.5	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.2	0.7	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.2	2.4	GO:0043101	purine-containing compound salvage(GO:0043101)
0.2	0.5	GO:0010447	response to acidic pH(GO:0010447)
0.2	0.5	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.2	1.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.2	1.7	GO:0006013	mannose metabolic process(GO:0006013)
0.2	0.5	GO:0006828	manganese ion transport(GO:0006828)
0.2	1.5	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.2	0.2	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.2	0.2	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.2	1.7	GO:0010288	response to lead ion(GO:0010288)
0.2	0.5	GO:0002507	tolerance induction(GO:0002507)
0.2	1.2	GO:0030851	granulocyte differentiation(GO:0030851)
0.2	0.5	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.2	0.7	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.2	0.2	GO:0032329	serine transport(GO:0032329)
0.2	0.2	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.2	4.3	GO:0019674	NAD metabolic process(GO:0019674)
0.2	0.7	GO:0045007	depurination(GO:0045007)
0.2	0.2	GO:0040009	regulation of growth rate(GO:0040009)
0.2	1.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.2	7.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.2	0.7	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.2	1.2	GO:0015840	urea transport(GO:0015840)
0.2	0.7	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.2	0.5	GO:0001881	receptor recycling(GO:0001881)
0.2	0.5	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.2	0.9	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.2	20.3	GO:0007159	leukocyte cell-cell adhesion(GO:0007159)
0.2	0.7	GO:0008053	mitochondrial fusion(GO:0008053)
0.2	0.9	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.2	1.8	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	1.2	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.2	0.5	GO:0030224	monocyte differentiation(GO:0030224)
0.2	4.4	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.2	0.9	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2	0.9	GO:0001906	cell killing(GO:0001906)
0.2	2.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2	0.5	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.2	0.7	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.2	0.9	GO:0009249	protein lipoylation(GO:0009249)
0.2	0.5	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.2	0.2	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.2	0.4	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.2	1.3	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2	0.4	GO:0002418	immune response to tumor cell(GO:0002418)
0.2	0.4	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.2	0.7	GO:0046548	retinal rod cell development(GO:0046548)
0.2	0.7	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2	0.2	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.2	0.7	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.2	0.7	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.2	0.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.2	0.6	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.2	1.3	GO:0016584	nucleosome positioning(GO:0016584)
0.2	1.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2	0.2	GO:0060037	pharyngeal system development(GO:0060037)
0.2	0.6	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.2	0.2	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.2	1.9	GO:0030225	macrophage differentiation(GO:0030225)
0.2	1.0	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.2	0.2	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.2	0.6	GO:0006667	sphinganine metabolic process(GO:0006667)
0.2	0.6	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.2	0.8	GO:0006855	drug transmembrane transport(GO:0006855)
0.2	0.2	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.2	1.7	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.2	1.4	GO:0006105	succinate metabolic process(GO:0006105)
0.2	1.0	GO:0030101	natural killer cell activation(GO:0030101)
0.2	0.8	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.2	0.2	GO:0021819	cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.2	1.8	GO:0016577	histone demethylation(GO:0016577)
0.2	1.0	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2	0.2	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.2	0.4	GO:0032202	telomere assembly(GO:0032202)
0.2	0.4	GO:0097576	vacuole fusion(GO:0097576)
0.2	0.6	GO:0032790	ribosome disassembly(GO:0032790)
0.2	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.2	0.8	GO:0042026	protein refolding(GO:0042026)
0.2	1.0	GO:0034311	sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.2	1.0	GO:0051383	kinetochore organization(GO:0051383)
0.2	0.8	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.2	1.4	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.2	0.4	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.2	0.4	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2	0.4	GO:0060972	left/right pattern formation(GO:0060972)
0.2	2.8	GO:0016578	histone deubiquitination(GO:0016578)
0.2	6.3	GO:0006968	cellular defense response(GO:0006968)
0.2	0.8	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2	0.6	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.2	0.8	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.2	0.4	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.2	0.4	GO:0048548	regulation of pinocytosis(GO:0048548)
0.2	0.4	GO:0033151	V(D)J recombination(GO:0033151)
0.2	0.2	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.2	0.4	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.2	1.0	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
0.2	0.6	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.2	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2	0.2	GO:0005997	xylulose metabolic process(GO:0005997)
0.2	1.7	GO:0009812	flavonoid metabolic process(GO:0009812)
0.2	1.5	GO:0006376	mRNA splice site selection(GO:0006376)
0.2	1.0	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2	0.2	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.2	0.6	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.2	0.4	GO:0060789	hair follicle placode formation(GO:0060789)
0.2	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.2	0.4	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.2	0.6	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.2	3.0	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.2	0.4	GO:0008298	intracellular mRNA localization(GO:0008298)
0.2	1.1	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.2	0.6	GO:0018094	protein polyglycylation(GO:0018094)
0.2	1.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.2	0.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.2	0.9	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.2	1.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.2	0.6	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2	0.6	GO:0060872	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.2	1.5	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.2	1.6	GO:0006027	aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027)
0.2	0.2	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.2	0.5	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.2	1.3	GO:0010039	response to iron ion(GO:0010039)
0.2	0.5	GO:0060120	auditory receptor cell fate commitment(GO:0009912) auditory receptor cell fate determination(GO:0042668) inner ear receptor cell fate commitment(GO:0060120)
0.2	1.1	GO:0000076	DNA replication checkpoint(GO:0000076)
0.2	2.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.2	9.0	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.2	0.5	GO:0007028	cytoplasm organization(GO:0007028)
0.2	0.7	GO:0034227	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.2	0.5	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	0.9	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.2	1.3	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.2	1.6	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.2	0.7	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.2	0.4	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.2	0.9	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2	0.7	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.2	1.8	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2	0.2	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.2	0.7	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.2	0.4	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.2	0.4	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.2	0.7	GO:0046037	GMP metabolic process(GO:0046037)
0.2	0.4	GO:0048002	antigen processing and presentation of peptide antigen(GO:0048002)
0.2	0.2	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.2	0.2	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.2	0.2	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.2	0.3	GO:0003159	endocardium development(GO:0003157) morphogenesis of an endothelium(GO:0003159) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.2	0.2	GO:0001302	replicative cell aging(GO:0001302)
0.2	1.6	GO:1902583	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.2	0.3	GO:0001705	ectoderm formation(GO:0001705)
0.2	2.8	GO:0032011	ARF protein signal transduction(GO:0032011)
0.2	2.4	GO:0016236	macroautophagy(GO:0016236)
0.2	0.9	GO:2000142	regulation of transcription initiation from RNA polymerase II promoter(GO:0060260) regulation of DNA-templated transcription, initiation(GO:2000142)
0.2	1.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.2	0.3	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.2	1.4	GO:0030833	regulation of actin filament polymerization(GO:0030833)
0.2	1.2	GO:2000117	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.2	0.3	GO:0052564	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.2	0.2	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.2	0.7	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.2	2.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.2	0.2	GO:0046931	pore complex assembly(GO:0046931)
0.2	0.2	GO:0045683	negative regulation of epidermis development(GO:0045683)
0.2	2.9	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.2	0.5	GO:0035092	sperm chromatin condensation(GO:0035092)
0.2	0.2	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.2	0.3	GO:0051299	centrosome separation(GO:0051299)
0.2	0.3	GO:0043457	regulation of cellular respiration(GO:0043457)
0.2	0.5	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2	0.5	GO:0006102	isocitrate metabolic process(GO:0006102)
0.2	2.0	GO:0016180	snRNA processing(GO:0016180)
0.2	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.2	1.2	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.2	0.3	GO:0018065	protein-cofactor linkage(GO:0018065)
0.2	0.5	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.2	1.0	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.2	0.7	GO:0006590	thyroid hormone generation(GO:0006590)
0.2	0.2	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.2	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.2	1.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.2	1.3	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2	0.2	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2	0.3	GO:0042420	dopamine catabolic process(GO:0042420)
0.2	0.2	GO:0031063	regulation of histone deacetylation(GO:0031063)
0.2	0.2	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.2	1.8	GO:0015804	neutral amino acid transport(GO:0015804)
0.2	1.1	GO:0016925	protein sumoylation(GO:0016925)
0.2	1.3	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.2	1.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.2	0.5	GO:0016559	peroxisome fission(GO:0016559)
0.2	1.3	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.2	0.8	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.2	0.2	GO:1902305	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2	1.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.2	1.3	GO:0000018	regulation of DNA recombination(GO:0000018)
0.2	0.5	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.2	0.8	GO:0006983	ER overload response(GO:0006983)
0.2	0.2	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.2	0.8	GO:1901571	icosanoid secretion(GO:0032309) icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.2	0.5	GO:0006999	nuclear pore organization(GO:0006999)
0.2	0.3	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.2	0.6	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.2	1.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.2	0.5	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2	0.3	GO:0019042	viral latency(GO:0019042)
0.2	1.5	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.2	0.2	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2	0.6	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.2	0.8	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.2	2.3	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.2	0.3	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.2	0.2	GO:0071482	cellular response to light stimulus(GO:0071482)
0.2	0.9	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.2	0.9	GO:0048247	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.2	0.5	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.3	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.4	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.7	GO:0006378	mRNA polyadenylation(GO:0006378)
0.1	3.7	GO:0016579	protein deubiquitination(GO:0016579)
0.1	0.3	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	1.0	GO:0046655	folic acid metabolic process(GO:0046655)
0.1	0.6	GO:0008089	anterograde axonal transport(GO:0008089)
0.1	1.0	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1	0.6	GO:0006776	vitamin A metabolic process(GO:0006776)
0.1	12.5	GO:0022904	respiratory electron transport chain(GO:0022904)
0.1	2.8	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.1	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.1	0.9	GO:0051642	centrosome localization(GO:0051642)
0.1	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	3.2	GO:0043966	histone H3 acetylation(GO:0043966)
0.1	0.3	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.3	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.1	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.1	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.1	0.4	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	3.7	GO:0006914	autophagy(GO:0006914)
0.1	0.4	GO:0006513	protein monoubiquitination(GO:0006513)
0.1	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.4	GO:0032506	cytokinetic process(GO:0032506)
0.1	2.4	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1	1.3	GO:0007141	male meiosis I(GO:0007141)
0.1	0.4	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1	0.4	GO:0031017	exocrine pancreas development(GO:0031017)
0.1	0.4	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.1	0.3	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.1	0.6	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1	4.2	GO:0034340	response to type I interferon(GO:0034340)
0.1	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	6.8	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1	0.5	GO:0044349	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.1	0.3	GO:0031047	gene silencing by RNA(GO:0031047)
0.1	0.3	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1	1.4	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.1	0.9	GO:0001706	endoderm formation(GO:0001706)
0.1	1.1	GO:0032365	intracellular lipid transport(GO:0032365)
0.1	0.1	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.1	0.3	GO:0046902	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.1	0.5	GO:0051340	regulation of ligase activity(GO:0051340)
0.1	2.7	GO:0043484	regulation of RNA splicing(GO:0043484)
0.1	3.2	GO:0043928	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	1.2	GO:0006379	mRNA cleavage(GO:0006379)
0.1	2.3	GO:0046649	lymphocyte activation(GO:0046649)
0.1	0.9	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.1	0.8	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.1	0.3	GO:0045010	actin nucleation(GO:0045010)
0.1	0.5	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	6.0	GO:0019395	fatty acid oxidation(GO:0019395) lipid oxidation(GO:0034440)
0.1	0.5	GO:0006612	protein targeting to membrane(GO:0006612)
0.1	1.2	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1	3.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.1	1.0	GO:0051322	anaphase(GO:0051322)
0.1	0.1	GO:0015865	purine nucleotide transport(GO:0015865)
0.1	0.5	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	9.7	GO:0050657	nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.1	0.1	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.1	0.8	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	0.6	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.1	0.4	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1	1.0	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.9	GO:0050957	equilibrioception(GO:0050957)
0.1	0.4	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.1	1.0	GO:0019184	glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.1	0.9	GO:0030903	notochord development(GO:0030903)
0.1	0.8	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	3.1	GO:0019319	hexose biosynthetic process(GO:0019319)
0.1	0.9	GO:0035967	cellular response to topologically incorrect protein(GO:0035967)
0.1	1.6	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.1	0.7	GO:0000080	mitotic G1 phase(GO:0000080)
0.1	0.1	GO:0032069	regulation of nuclease activity(GO:0032069)
0.1	0.4	GO:0006562	proline catabolic process(GO:0006562)
0.1	2.3	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.1	0.2	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	0.4	GO:1903319	positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.1	0.5	GO:0042447	hormone catabolic process(GO:0042447)
0.1	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1	1.3	GO:0032092	positive regulation of protein binding(GO:0032092)
0.1	0.6	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.4	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.5	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.1	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.1	0.7	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1	4.1	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.1	0.7	GO:0009062	fatty acid catabolic process(GO:0009062)
0.1	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.1	1.1	GO:0030071	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.1	36.7	GO:0006955	immune response(GO:0006955)
0.1	0.2	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.1	0.4	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.1	0.5	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.7	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.1	0.9	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.1	0.1	GO:0042503	tyrosine phosphorylation of Stat3 protein(GO:0042503)
0.1	0.7	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.9	GO:0007020	microtubule nucleation(GO:0007020)
0.1	0.1	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1	1.7	GO:0009303	rRNA transcription(GO:0009303)
0.1	4.2	GO:0007051	spindle organization(GO:0007051)
0.1	0.5	GO:0046427	positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.5	GO:0050684	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.1	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.3	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.1	0.2	GO:0000239	pachytene(GO:0000239)
0.1	0.7	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.1	2.3	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.1	0.9	GO:0006541	glutamine metabolic process(GO:0006541)
0.1	4.0	GO:0000082	G1/S transition of mitotic cell cycle(GO:0000082) cell cycle G1/S phase transition(GO:0044843)
0.1	20.0	GO:0016568	chromatin modification(GO:0016568)
0.1	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.1	0.1	GO:1904358	regulation of telomere maintenance via telomerase(GO:0032210) positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1	0.4	GO:0019048	modulation by virus of host morphology or physiology(GO:0019048)
0.1	0.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	0.2	GO:0033133	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.1	0.2	GO:0000266	mitochondrial fission(GO:0000266)
0.1	0.2	GO:0046398	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.1	0.5	GO:0032006	regulation of TOR signaling(GO:0032006)
0.1	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1	1.2	GO:0008154	actin polymerization or depolymerization(GO:0008154)
0.1	1.3	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1	0.6	GO:0010921	regulation of phosphatase activity(GO:0010921)
0.1	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658) alditol phosphate metabolic process(GO:0052646)
0.1	0.2	GO:0018195	peptidyl-arginine modification(GO:0018195)
0.1	0.6	GO:0015671	oxygen transport(GO:0015671)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.6	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1	1.9	GO:0000956	nuclear-transcribed mRNA catabolic process(GO:0000956)
0.1	0.2	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.1	0.3	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.2	GO:0070977	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.1	0.2	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.1	0.3	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.1	GO:0010985	negative regulation of lipoprotein particle clearance(GO:0010985)
0.1	0.5	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.1	0.1	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.1	0.2	GO:0060179	male mating behavior(GO:0060179)
0.1	0.3	GO:0007506	gonadal mesoderm development(GO:0007506)
0.1	0.2	GO:0046479	glycosphingolipid catabolic process(GO:0046479)
0.1	0.4	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.5	GO:0006004	fucose metabolic process(GO:0006004)
0.1	0.2	GO:0009405	pathogenesis(GO:0009405)
0.1	0.5	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.1	0.2	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1	0.4	GO:0055070	copper ion homeostasis(GO:0055070)
0.1	0.8	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.3	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.1	7.7	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1	6.8	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.1	5.7	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.1	1.5	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.1	0.2	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.1	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	3.3	GO:0000087	mitotic M phase(GO:0000087)
0.1	0.5	GO:0034453	microtubule anchoring(GO:0034453)
0.1	0.4	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.1	0.4	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1	5.9	GO:0008380	RNA splicing(GO:0008380)
0.1	0.4	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.6	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.1	2.5	GO:0006818	hydrogen transport(GO:0006818)
0.1	0.3	GO:0015886	heme transport(GO:0015886)
0.1	0.9	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.1	0.3	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.1	0.7	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	2.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.1	0.2	GO:0042732	D-xylose metabolic process(GO:0042732)
0.1	6.1	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1	3.3	GO:0006413	translational initiation(GO:0006413)
0.1	3.7	GO:0016071	mRNA metabolic process(GO:0016071)
0.1	0.1	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	0.7	GO:0042572	retinol metabolic process(GO:0042572)
0.1	0.8	GO:0000209	protein polyubiquitination(GO:0000209)
0.1	0.3	GO:0048240	sperm capacitation(GO:0048240)
0.1	0.8	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.1	0.1	GO:0060456	regulation of saliva secretion(GO:0046877) positive regulation of digestive system process(GO:0060456)
0.1	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.1	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.2	GO:0009698	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.1	0.2	GO:0034372	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.1	0.7	GO:0050832	defense response to fungus(GO:0050832)
0.1	1.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	3.2	GO:0006754	ATP biosynthetic process(GO:0006754)
0.1	0.3	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.1	0.2	GO:0015705	iodide transport(GO:0015705)
0.1	0.3	GO:0015669	gas transport(GO:0015669)
0.1	0.2	GO:0044774	mitotic DNA integrity checkpoint(GO:0044774)
0.1	0.2	GO:0006573	valine metabolic process(GO:0006573)
0.1	0.3	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1	0.7	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.1	0.2	GO:0098781	ncRNA transcription(GO:0098781)
0.1	0.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.5	GO:1902221	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.6	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.2	GO:0006691	leukotriene metabolic process(GO:0006691)
0.1	0.2	GO:0090022	regulation of granulocyte chemotaxis(GO:0071622) regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.1	0.5	GO:0007635	chemosensory behavior(GO:0007635)
0.1	0.7	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.1	GO:0006301	postreplication repair(GO:0006301)
0.1	0.2	GO:0006448	regulation of translational elongation(GO:0006448)
0.1	0.1	GO:0021984	adenohypophysis development(GO:0021984)
0.1	0.2	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.4	GO:0043586	tongue development(GO:0043586)
0.1	2.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.1	0.2	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	0.5	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.1	0.3	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.1	0.2	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1	0.1	GO:0060117	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) auditory receptor cell development(GO:0060117)
0.1	0.1	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.1	0.5	GO:0007005	mitochondrion organization(GO:0007005)
0.1	0.2	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.1	0.3	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.1	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.1	GO:0090501	RNA phosphodiester bond hydrolysis(GO:0090501)
0.1	8.7	GO:0043087	regulation of GTPase activity(GO:0043087)
0.1	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.1	4.9	GO:0006364	rRNA processing(GO:0006364) rRNA metabolic process(GO:0016072)
0.1	0.1	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.1	0.3	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	4.4	GO:0006415	translational termination(GO:0006415)
0.1	0.1	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.1	0.4	GO:0033363	secretory granule organization(GO:0033363)
0.1	0.9	GO:0042398	cellular modified amino acid biosynthetic process(GO:0042398)
0.1	0.4	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.1	0.2	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.1	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080) metaphase plate congression(GO:0051310)
0.1	0.2	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.1	0.4	GO:0006547	histidine metabolic process(GO:0006547)
0.1	0.4	GO:0000819	sister chromatid segregation(GO:0000819)
0.1	0.9	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.1	0.3	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.1	0.2	GO:0006312	mitotic recombination(GO:0006312)
0.1	0.4	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.1	1.3	GO:0031647	regulation of protein stability(GO:0031647)
0.1	0.9	GO:0006289	nucleotide-excision repair(GO:0006289)
0.1	0.1	GO:0007006	mitochondrial membrane organization(GO:0007006)
0.1	0.2	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.2	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.3	GO:0007128	meiotic prophase I(GO:0007128)
0.1	0.2	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.1	3.4	GO:0008033	tRNA processing(GO:0008033)
0.1	0.3	GO:0000050	urea cycle(GO:0000050)
0.1	0.9	GO:0006672	ceramide metabolic process(GO:0006672)
0.1	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.3	GO:0045909	positive regulation of vasodilation(GO:0045909)
0.1	0.1	GO:0034694	response to prostaglandin(GO:0034694)
0.1	0.1	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.1	0.4	GO:0008105	asymmetric protein localization(GO:0008105)
0.1	0.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.2	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.4	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.1	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.1	0.1	GO:0065005	high-density lipoprotein particle assembly(GO:0034380) protein-lipid complex assembly(GO:0065005)
0.1	0.5	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.1	0.9	GO:0051693	actin filament capping(GO:0051693)
0.1	0.2	GO:0014888	striated muscle adaptation(GO:0014888)
0.1	0.1	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	0.1	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.1	0.1	GO:0010870	positive regulation of receptor biosynthetic process(GO:0010870)
0.1	0.2	GO:0072666	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.1	0.1	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.1	0.1	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1	0.1	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.1	0.2	GO:0001510	RNA methylation(GO:0001510)
0.1	0.2	GO:0051775	response to redox state(GO:0051775)
0.1	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.1	10.6	GO:0006412	translation(GO:0006412)
0.1	0.6	GO:0006401	RNA catabolic process(GO:0006401)
0.1	0.4	GO:0006465	signal peptide processing(GO:0006465)
0.1	0.2	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1	0.1	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.1	0.2	GO:0021694	cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	1.0	GO:0072655	protein localization to mitochondrion(GO:0070585) establishment of protein localization to mitochondrion(GO:0072655)
0.1	0.2	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.1	0.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1	1.1	GO:0002682	regulation of immune system process(GO:0002682)
0.1	0.1	GO:0001743	optic placode formation(GO:0001743)
0.1	0.8	GO:0019400	alditol metabolic process(GO:0019400)
0.1	0.3	GO:0070972	protein targeting to ER(GO:0045047) protein localization to endoplasmic reticulum(GO:0070972) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.1	0.2	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.1	0.6	GO:0019433	triglyceride catabolic process(GO:0019433)
0.1	0.1	GO:0001821	histamine secretion(GO:0001821)
0.1	0.3	GO:0002440	production of molecular mediator of immune response(GO:0002440)
0.1	0.3	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.1	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.1	0.4	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	0.6	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.1	0.2	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0045005	DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0	0.3	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.2	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.0	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.0	GO:0043247	telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	4.5	GO:0006281	DNA repair(GO:0006281)
0.0	0.1	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.1	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.3	GO:0006862	nucleotide transport(GO:0006862)
0.0	0.2	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.0	GO:0021696	cerebellar cortex morphogenesis(GO:0021696)
0.0	0.0	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.2	GO:0006839	mitochondrial transport(GO:0006839)
0.0	0.1	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	1.1	GO:1901607	alpha-amino acid biosynthetic process(GO:1901607)
0.0	0.2	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.5	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	1.0	GO:0030099	myeloid cell differentiation(GO:0030099)
0.0	0.3	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	1.6	GO:0006821	chloride transport(GO:0006821)
0.0	0.1	GO:0030147	obsolete natriuresis(GO:0030147)
0.0	0.0	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.2	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.4	GO:0031023	microtubule organizing center organization(GO:0031023)
0.0	0.1	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.0	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.2	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.7	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.2	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.2	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.0	0.6	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.4	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:0030320	cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.4	GO:0007339	binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0015793	renal water transport(GO:0003097) glycerol transport(GO:0015793) cellular response to mercury ion(GO:0071288)
0.0	1.0	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.0	0.1	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	5.4	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.0	0.0	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.3	GO:1901071	glucosamine-containing compound metabolic process(GO:1901071)
0.0	0.1	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.0	GO:0060896	neural plate pattern specification(GO:0060896)
0.0	0.0	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	1.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.0	GO:0055069	cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.6	GO:0000187	activation of MAPK activity(GO:0000187)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	0.1	GO:0006997	nucleus organization(GO:0006997)
0.0	0.1	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
0.0	0.1	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.6	GO:0007602	phototransduction(GO:0007602)
0.0	0.1	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.1	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.0	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.9	GO:0008654	phospholipid biosynthetic process(GO:0008654)
0.0	0.2	GO:0043414	macromolecule methylation(GO:0043414)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.2	GO:0051899	membrane depolarization(GO:0051899)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0043049	otic placode formation(GO:0043049)
0.0	0.1	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.5	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.0	GO:0033505	floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.6	GO:0061025	membrane fusion(GO:0061025)
0.0	0.0	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0051904	pigment granule transport(GO:0051904)
0.0	0.0	GO:0043526	obsolete neuroprotection(GO:0043526)
0.0	0.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.0	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0048925	sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0	0.6	GO:0050909	sensory perception of taste(GO:0050909)
0.0	1.7	GO:0006470	protein dephosphorylation(GO:0006470)
0.0	0.0	GO:0032623	interleukin-2 production(GO:0032623)
0.0	0.2	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0070646	protein modification by small protein removal(GO:0070646)
0.0	0.1	GO:0051923	sulfation(GO:0051923)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0032200	telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0	0.0	GO:0070227	lymphocyte apoptotic process(GO:0070227) regulation of lymphocyte apoptotic process(GO:0070228) T cell apoptotic process(GO:0070231) regulation of T cell apoptotic process(GO:0070232)
0.0	0.0	GO:0030832	regulation of actin filament length(GO:0030832)
0.0	0.0	GO:0051304	chromosome separation(GO:0051304)
0.0	0.1	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	1.7	GO:0044419	interspecies interaction between organisms(GO:0044419)
0.0	0.0	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.0	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	4.5	GO:0007608	sensory perception of smell(GO:0007608)
0.0	0.0	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	4.7	GO:0005826	actomyosin contractile ring(GO:0005826)
1.1	2.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
1.0	12.2	GO:0001772	immunological synapse(GO:0001772)
0.9	3.5	GO:0070820	tertiary granule(GO:0070820)
0.8	1.7	GO:0044462	external encapsulating structure part(GO:0044462)
0.8	4.8	GO:0031264	death-inducing signaling complex(GO:0031264)
0.7	2.2	GO:0072487	MSL complex(GO:0072487)
0.7	2.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.7	5.9	GO:0042101	T cell receptor complex(GO:0042101)
0.5	1.6	GO:0042629	mast cell granule(GO:0042629)
0.5	4.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.5	3.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.5	2.4	GO:0070695	FHF complex(GO:0070695)
0.5	1.4	GO:0032009	early phagosome(GO:0032009)
0.5	2.8	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.5	5.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.4	3.5	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.4	0.4	GO:0030312	external encapsulating structure(GO:0030312)
0.4	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4	2.8	GO:0070688	MLL5-L complex(GO:0070688)
0.4	1.6	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4	1.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.4	1.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.3	1.4	GO:0035189	Rb-E2F complex(GO:0035189)
0.3	1.4	GO:0001891	phagocytic cup(GO:0001891)
0.3	1.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3	3.7	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.3	4.7	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.3	2.3	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.3	0.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.3	0.6	GO:0031932	TORC2 complex(GO:0031932)
0.3	0.9	GO:0031904	endosome lumen(GO:0031904)
0.3	1.5	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3	1.5	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.3	1.5	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3	0.9	GO:0001652	granular component(GO:0001652)
0.3	1.7	GO:0071778	obsolete WINAC complex(GO:0071778)
0.3	2.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.3	1.1	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3	1.1	GO:0005827	polar microtubule(GO:0005827)
0.3	5.6	GO:0031519	PcG protein complex(GO:0031519)
0.3	0.8	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.3	0.8	GO:0008537	proteasome activator complex(GO:0008537)
0.3	2.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.3	1.8	GO:0008290	F-actin capping protein complex(GO:0008290)
0.3	0.8	GO:0030008	TRAPP complex(GO:0030008)
0.3	1.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.3	1.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.3	2.5	GO:0090533	cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.2	1.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.2	1.0	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.2	2.2	GO:0000242	pericentriolar material(GO:0000242)
0.2	1.0	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	3.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	0.7	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.2	0.7	GO:0071564	npBAF complex(GO:0071564)
0.2	0.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.2	0.9	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.2	0.7	GO:0033553	rDNA heterochromatin(GO:0033553)
0.2	1.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.2	0.6	GO:0005594	collagen type IX trimer(GO:0005594)
0.2	14.5	GO:0005643	nuclear pore(GO:0005643)
0.2	0.9	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2	0.6	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2	0.2	GO:0070938	contractile ring(GO:0070938)
0.2	0.4	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.2	2.3	GO:0045335	phagocytic vesicle(GO:0045335)
0.2	0.8	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	0.6	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	1.2	GO:0005869	dynactin complex(GO:0005869)
0.2	2.0	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.2	1.2	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.2	1.0	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.2	2.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.2	0.8	GO:0000800	lateral element(GO:0000800)
0.2	1.8	GO:0022624	proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.2	10.3	GO:0016605	PML body(GO:0016605)
0.2	0.2	GO:0070552	BRISC complex(GO:0070552)
0.2	0.6	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2	0.6	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	3.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.2	1.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.2	1.1	GO:0005811	lipid particle(GO:0005811)
0.2	3.2	GO:0031201	SNARE complex(GO:0031201)
0.2	0.7	GO:0042825	TAP complex(GO:0042825)
0.2	1.7	GO:0042575	DNA polymerase complex(GO:0042575)
0.2	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2	0.7	GO:0034451	centriolar satellite(GO:0034451)
0.2	0.6	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.2	0.7	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.2	2.1	GO:0032039	integrator complex(GO:0032039)
0.2	1.6	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2	1.0	GO:0000125	PCAF complex(GO:0000125)
0.2	0.7	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.2	0.5	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2	2.2	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2	1.5	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.2	0.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.2	0.8	GO:0002080	acrosomal membrane(GO:0002080)
0.2	0.5	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2	1.0	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2	4.7	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.2	0.2	GO:0038201	TOR complex(GO:0038201)
0.2	3.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2	0.3	GO:0042599	lamellar body(GO:0042599)
0.2	5.9	GO:0031970	organelle envelope lumen(GO:0031970)
0.2	0.3	GO:0030125	clathrin vesicle coat(GO:0030125)
0.2	1.0	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.2	1.8	GO:0042588	zymogen granule(GO:0042588)
0.2	1.0	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2	0.5	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.2	1.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.2	1.7	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2	2.0	GO:0005657	replication fork(GO:0005657)
0.2	14.8	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.2	2.9	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	1.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.2	4.8	GO:0016592	mediator complex(GO:0016592)
0.2	5.2	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.2	2.5	GO:0032420	stereocilium(GO:0032420)
0.2	0.6	GO:0000930	gamma-tubulin complex(GO:0000930)
0.2	33.6	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2	0.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	1.2	GO:0042555	MCM complex(GO:0042555)
0.1	1.8	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.1	1.9	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	0.9	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.1	3.0	GO:0042612	MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.1	1.0	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.4	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.6	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.6	GO:0042382	paraspeckles(GO:0042382)
0.1	1.6	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.1	0.3	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	1.8	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	0.6	GO:0015935	small ribosomal subunit(GO:0015935)
0.1	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	3.6	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1	5.3	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	1.0	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	1.9	GO:0005844	polysome(GO:0005844)
0.1	1.0	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1	6.5	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.1	0.7	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.4	GO:0071817	MMXD complex(GO:0071817)
0.1	0.8	GO:0000346	transcription export complex(GO:0000346)
0.1	0.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.1	0.5	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.1	0.5	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	1.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	2.8	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	0.5	GO:0001740	Barr body(GO:0001740)
0.1	1.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	1.2	GO:0030914	STAGA complex(GO:0030914)
0.1	0.4	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.3	GO:0042827	platelet dense granule(GO:0042827)
0.1	0.6	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.1	0.4	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	1.0	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.9	GO:0005683	U7 snRNP(GO:0005683)
0.1	0.9	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.2	GO:0008278	cohesin complex(GO:0008278)
0.1	0.2	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.1	2.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	2.1	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	0.4	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	1.3	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.6	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	2.1	GO:0070469	respiratory chain(GO:0070469)
0.1	1.4	GO:0005839	proteasome core complex(GO:0005839)
0.1	0.6	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.1	7.1	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.1	0.2	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.2	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.1	0.6	GO:1990204	oxidoreductase complex(GO:1990204)
0.1	1.0	GO:0008180	COP9 signalosome(GO:0008180)
0.1	9.0	GO:0032993	protein-DNA complex(GO:0032993)
0.1	0.3	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.3	GO:0000124	SAGA complex(GO:0000124)
0.1	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	1.1	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.1	0.2	GO:0042581	specific granule(GO:0042581)
0.1	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	5.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.6	GO:0034464	BBSome(GO:0034464)
0.1	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.3	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	1.0	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	72.0	GO:0005654	nucleoplasm(GO:0005654)
0.1	4.8	GO:0005681	spliceosomal complex(GO:0005681)
0.1	2.3	GO:0016363	nuclear matrix(GO:0016363)
0.1	1.8	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	1.1	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1	1.4	GO:0005796	Golgi lumen(GO:0005796)
0.1	1.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	5.7	GO:0031301	integral component of organelle membrane(GO:0031301)
0.1	1.5	GO:0000776	kinetochore(GO:0000776)
0.1	0.6	GO:0000145	exocyst(GO:0000145)
0.1	1.4	GO:0030175	filopodium(GO:0030175)
0.1	0.7	GO:0030684	preribosome(GO:0030684)
0.1	0.2	GO:0001741	XY body(GO:0001741)
0.1	2.0	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.1	2.8	GO:0000502	proteasome complex(GO:0000502)
0.1	25.7	GO:0005768	endosome(GO:0005768)
0.1	6.6	GO:0000785	chromatin(GO:0000785)
0.1	2.7	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	10.0	GO:0005819	spindle(GO:0005819)
0.1	1.4	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.1	0.3	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.4	GO:0033011	perinuclear theca(GO:0033011)
0.1	0.8	GO:0000178	exosome (RNase complex)(GO:0000178)
0.1	0.4	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	0.2	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.1	0.5	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1	0.4	GO:0032590	dendrite membrane(GO:0032590)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.9	GO:0044439	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1	0.7	GO:0016272	prefoldin complex(GO:0016272)
0.1	0.4	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1	109.1	GO:0005829	cytosol(GO:0005829)
0.1	1.3	GO:0030496	midbody(GO:0030496)
0.1	0.4	GO:0032389	MutLalpha complex(GO:0032389)
0.1	0.3	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.1	0.4	GO:0000796	condensin complex(GO:0000796)
0.1	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.1	0.3	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	4.8	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.7	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	6.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1	3.1	GO:0031965	nuclear membrane(GO:0031965)
0.1	1.3	GO:0031526	brush border membrane(GO:0031526)
0.1	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.1	0.2	GO:0005903	brush border(GO:0005903)
0.1	21.4	GO:0044429	mitochondrial part(GO:0044429)
0.1	1.1	GO:0001533	cornified envelope(GO:0001533)
0.1	0.5	GO:0005884	actin filament(GO:0005884)
0.1	2.3	GO:0005840	ribosome(GO:0005840)
0.1	0.3	GO:0031461	cullin-RING ubiquitin ligase complex(GO:0031461)
0.1	3.7	GO:0005694	chromosome(GO:0005694)
0.1	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	31.8	GO:0005730	nucleolus(GO:0005730)
0.1	0.4	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.7	GO:0030057	desmosome(GO:0030057)
0.1	0.2	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.1	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.3	GO:0017119	Golgi transport complex(GO:0017119)
0.1	0.2	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1	2.8	GO:0005813	centrosome(GO:0005813)
0.1	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.1	1.8	GO:0098802	plasma membrane receptor complex(GO:0098802)
0.1	0.8	GO:0005802	trans-Golgi network(GO:0005802)
0.1	1.2	GO:0005921	gap junction(GO:0005921)
0.1	19.9	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.1	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	15.2	GO:0005739	mitochondrion(GO:0005739)
0.0	0.3	GO:0016234	inclusion body(GO:0016234)
0.0	0.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.0	GO:0030880	RNA polymerase complex(GO:0030880)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	3.8	GO:0005625	obsolete soluble fraction(GO:0005625)
0.0	0.1	GO:0032838	cell projection cytoplasm(GO:0032838)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.2	GO:0048475	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0	0.4	GO:0030027	lamellipodium(GO:0030027)
0.0	0.0	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.6	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.0	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.2	GO:0031513	nonmotile primary cilium(GO:0031513)
0.0	0.1	GO:0060170	ciliary membrane(GO:0060170)
0.0	2.3	GO:0005624	obsolete membrane fraction(GO:0005624)
0.0	0.1	GO:0098858	actin-based cell projection(GO:0098858)
0.0	0.0	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.7	GO:0035184	histone threonine kinase activity(GO:0035184)
1.4	4.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
1.2	3.5	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9	5.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.8	5.1	GO:0001727	lipid kinase activity(GO:0001727)
0.8	3.9	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.8	2.4	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.8	2.3	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.8	2.3	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.7	2.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.7	2.9	GO:0004974	leukotriene receptor activity(GO:0004974)
0.7	2.1	GO:0042608	T cell receptor binding(GO:0042608)
0.7	2.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.7	11.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.6	1.8	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.6	4.7	GO:0005522	profilin binding(GO:0005522)
0.6	1.7	GO:0070644	vitamin D response element binding(GO:0070644)
0.6	1.7	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.5	3.8	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.5	2.7	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.5	2.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.5	4.2	GO:0050700	CARD domain binding(GO:0050700)
0.5	1.5	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5	3.4	GO:0004568	chitinase activity(GO:0004568)
0.5	1.4	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.5	1.9	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5	2.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5	5.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.5	2.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.5	4.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.5	1.4	GO:0035197	siRNA binding(GO:0035197)
0.4	0.4	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.4	22.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.4	4.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.4	2.7	GO:0051400	BH domain binding(GO:0051400)
0.4	1.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.4	1.7	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.4	1.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.4	1.7	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.4	1.7	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.4	2.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.4	4.2	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.4	16.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.4	1.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.4	2.5	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.4	1.2	GO:0001849	complement component C1q binding(GO:0001849)
0.4	2.4	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.4	2.4	GO:0042834	peptidoglycan binding(GO:0042834)
0.4	7.1	GO:0043621	protein self-association(GO:0043621)
0.4	3.2	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.4	2.4	GO:0004969	histamine receptor activity(GO:0004969)
0.4	1.2	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.4	3.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.4	0.4	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.4	3.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.4	1.5	GO:0070492	oligosaccharide binding(GO:0070492)
0.4	1.5	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.4	1.5	GO:0008420	CTD phosphatase activity(GO:0008420)
0.4	2.6	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.4	1.5	GO:0008518	reduced folate carrier activity(GO:0008518)
0.4	2.6	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.4	1.5	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.4	1.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.4	1.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.4	1.8	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.3	1.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3	1.0	GO:0043398	HLH domain binding(GO:0043398)
0.3	0.7	GO:0001846	opsonin binding(GO:0001846)
0.3	1.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3	1.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.3	1.3	GO:0045569	TRAIL binding(GO:0045569)
0.3	1.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.3	1.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.3	0.7	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.3	1.3	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.3	2.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.3	1.9	GO:0005521	lamin binding(GO:0005521)
0.3	1.0	GO:0004875	complement receptor activity(GO:0004875)
0.3	1.6	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.3	0.9	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3	0.3	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.3	0.3	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.3	0.6	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.3	0.3	GO:0032052	bile acid binding(GO:0032052)
0.3	0.9	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.3	4.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.3	0.9	GO:0015254	glycerol channel activity(GO:0015254)
0.3	1.5	GO:0031685	adenosine receptor binding(GO:0031685)
0.3	0.9	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3	0.9	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.3	2.6	GO:0019864	IgG binding(GO:0019864)
0.3	1.2	GO:0004340	glucokinase activity(GO:0004340)
0.3	1.2	GO:0043495	protein anchor(GO:0043495)
0.3	1.7	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3	0.9	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.3	1.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.3	2.0	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.3	0.8	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.3	2.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.3	0.8	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.3	1.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3	1.6	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.3	1.9	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.3	0.3	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.3	0.8	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.3	0.5	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.3	0.8	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.3	1.1	GO:0048156	tau protein binding(GO:0048156)
0.3	0.8	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.3	1.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.3	5.5	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3	0.8	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.3	4.7	GO:0050699	WW domain binding(GO:0050699)
0.3	0.8	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3	3.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.3	1.0	GO:0030911	TPR domain binding(GO:0030911)
0.3	0.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.3	3.8	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3	0.3	GO:0008242	omega peptidase activity(GO:0008242)
0.3	2.6	GO:0004697	protein kinase C activity(GO:0004697)
0.3	0.5	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.3	2.8	GO:0016854	racemase and epimerase activity(GO:0016854)
0.3	0.8	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.3	2.5	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.3	3.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.2	1.5	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2	1.0	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.2	1.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.2	0.7	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.2	7.4	GO:0003823	antigen binding(GO:0003823)
0.2	1.5	GO:0051920	peroxiredoxin activity(GO:0051920)
0.2	1.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2	1.2	GO:0004904	interferon receptor activity(GO:0004904)
0.2	6.1	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2	0.7	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.2	1.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.2	0.5	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.2	0.7	GO:0004370	glycerol kinase activity(GO:0004370)
0.2	0.9	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.2	1.9	GO:0003785	actin monomer binding(GO:0003785)
0.2	0.9	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.2	0.7	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2	2.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.2	3.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.2	0.9	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2	0.9	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.2	0.2	GO:0019956	chemokine binding(GO:0019956)
0.2	0.4	GO:0003917	DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.2	1.8	GO:0001671	ATPase activator activity(GO:0001671)
0.2	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.2	2.7	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.2	1.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.2	0.7	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.2	1.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.2	2.2	GO:0008199	ferric iron binding(GO:0008199)
0.2	1.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.2	1.5	GO:0031701	angiotensin receptor binding(GO:0031701)
0.2	0.9	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.2	0.7	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.2	0.7	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2	2.4	GO:0017091	AU-rich element binding(GO:0017091)
0.2	0.4	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.2	0.6	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.2	0.6	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2	1.7	GO:0030371	translation repressor activity(GO:0030371)
0.2	0.6	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2	2.3	GO:0042169	SH2 domain binding(GO:0042169)
0.2	0.9	GO:0046790	virion binding(GO:0046790)
0.2	0.6	GO:0000400	four-way junction DNA binding(GO:0000400)
0.2	0.6	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.2	0.2	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2	0.8	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.2	4.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	0.2	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.2	0.4	GO:0030955	potassium ion binding(GO:0030955)
0.2	1.0	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.2	2.5	GO:0017069	snRNA binding(GO:0017069)
0.2	1.2	GO:0016778	diphosphotransferase activity(GO:0016778)
0.2	1.9	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2	0.8	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.2	0.8	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.2	0.4	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2	0.8	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.2	0.8	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.2	1.0	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2	1.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.2	5.9	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.2	1.0	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2	0.6	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.2	0.6	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2	0.2	GO:0004396	hexokinase activity(GO:0004396)
0.2	2.9	GO:0000030	mannosyltransferase activity(GO:0000030)
0.2	1.4	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2	0.8	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.2	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.2	5.6	GO:0016831	carboxy-lyase activity(GO:0016831)
0.2	0.8	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.2	1.3	GO:0001614	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.2	0.6	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.2	1.7	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.2	3.8	GO:0048487	beta-tubulin binding(GO:0048487)
0.2	0.8	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	0.6	GO:0032405	MutLalpha complex binding(GO:0032405)
0.2	0.9	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2	0.6	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.2	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.2	6.0	GO:0019210	kinase inhibitor activity(GO:0019210)
0.2	0.9	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.2	0.9	GO:0015288	porin activity(GO:0015288)
0.2	1.7	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.2	1.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.2	0.4	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2	7.1	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.2	0.5	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.2	0.2	GO:0071723	lipopeptide binding(GO:0071723)
0.2	0.7	GO:0004383	guanylate cyclase activity(GO:0004383)
0.2	0.5	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2	0.7	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2	0.5	GO:0016748	succinyltransferase activity(GO:0016748)
0.2	1.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.2	0.7	GO:0032452	histone demethylase activity(GO:0032452)
0.2	0.7	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.2	1.1	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.2	0.5	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2	0.5	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.2	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.2	0.5	GO:0004000	adenosine deaminase activity(GO:0004000)
0.2	3.6	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2	0.3	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2	0.5	GO:0043130	ubiquitin binding(GO:0043130)
0.2	0.2	GO:0005035	death receptor activity(GO:0005035)
0.2	1.0	GO:0050733	RS domain binding(GO:0050733)
0.2	4.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.2	4.2	GO:0003724	RNA helicase activity(GO:0003724)
0.2	0.2	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.2	1.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.2	0.2	GO:0004532	exoribonuclease activity(GO:0004532)
0.2	7.9	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.2	0.5	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2	1.6	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2	0.3	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2	6.7	GO:0004896	cytokine receptor activity(GO:0004896)
0.2	1.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.2	0.5	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2	2.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.2	1.5	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.2	2.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	1.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.2	1.6	GO:0010181	FMN binding(GO:0010181)
0.2	0.5	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.2	0.5	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.2	2.1	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.2	0.8	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2	0.5	GO:0015929	hexosaminidase activity(GO:0015929)
0.2	2.4	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.2	1.6	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.2	4.1	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.2	0.6	GO:0005536	glucose binding(GO:0005536)
0.2	0.5	GO:0034235	GPI anchor binding(GO:0034235)
0.2	0.5	GO:0043515	kinetochore binding(GO:0043515)
0.2	0.8	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.2	0.6	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2	0.6	GO:0031013	troponin I binding(GO:0031013)
0.2	5.5	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2	6.4	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.2	0.3	GO:0034617	nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.2	0.9	GO:0070402	NADPH binding(GO:0070402)
0.2	0.8	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.2	0.9	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2	0.5	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.4	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	0.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.6	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	1.6	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	0.7	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.7	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	0.4	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	1.3	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	0.6	GO:0031014	troponin T binding(GO:0031014)
0.1	1.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	1.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	7.0	GO:0042393	histone binding(GO:0042393)
0.1	0.4	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	1.6	GO:0016830	carbon-carbon lyase activity(GO:0016830)
0.1	5.3	GO:0008276	protein methyltransferase activity(GO:0008276)
0.1	1.6	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1	0.4	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	3.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.6	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.6	GO:0070513	death domain binding(GO:0070513)
0.1	2.6	GO:0051219	phosphoprotein binding(GO:0051219)
0.1	1.4	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.1	0.3	GO:0032404	mismatch repair complex binding(GO:0032404)
0.1	0.3	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.1	0.3	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.7	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.4	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	0.5	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1	4.6	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	0.7	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.1	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.1	1.1	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	0.7	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.1	0.4	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.4	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.8	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.8	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.3	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.1	0.4	GO:0004802	transketolase activity(GO:0004802)
0.1	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	1.6	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.4	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	2.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	0.6	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.1	0.6	GO:0032451	demethylase activity(GO:0032451)
0.1	1.3	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.1	0.5	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.1	0.6	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.4	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.2	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.1	2.9	GO:0015459	potassium channel regulator activity(GO:0015459)
0.1	0.4	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.1	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	1.1	GO:0042171	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1	0.6	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.4	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	1.9	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1	1.6	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	4.4	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1	0.7	GO:0009922	fatty acid elongase activity(GO:0009922)
0.1	0.1	GO:0031420	alkali metal ion binding(GO:0031420)
0.1	2.2	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1	0.3	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.7	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	1.9	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.1	0.2	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	0.4	GO:0017089	glycolipid transporter activity(GO:0017089)
0.1	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1	1.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.1	0.3	GO:0060590	ATPase regulator activity(GO:0060590)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	1.0	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1	1.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.1	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1	1.0	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	0.9	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	1.2	GO:0004659	prenyltransferase activity(GO:0004659)
0.1	0.2	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.1	0.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.3	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	2.3	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	11.7	GO:0000287	magnesium ion binding(GO:0000287)
0.1	1.8	GO:0051540	iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.1	1.9	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.1	3.3	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.1	0.3	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.5	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.8	GO:0003678	DNA helicase activity(GO:0003678)
0.1	6.0	GO:0008565	protein transporter activity(GO:0008565)
0.1	0.5	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.4	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.5	GO:0016208	AMP binding(GO:0016208)
0.1	0.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.4	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	4.8	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	0.4	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	0.8	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1	3.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	2.6	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.1	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	1.0	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	1.3	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.1	1.8	GO:0019003	GDP binding(GO:0019003)
0.1	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.3	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.4	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	0.1	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.1	2.9	GO:0004177	aminopeptidase activity(GO:0004177)
0.1	1.0	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.5	GO:0031369	translation initiation factor binding(GO:0031369)
0.1	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.1	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.1	0.3	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	0.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.3	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	0.7	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1	0.9	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	0.5	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	0.9	GO:0003924	GTPase activity(GO:0003924)
0.1	7.2	GO:0051082	unfolded protein binding(GO:0051082)
0.1	0.3	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.1	0.2	GO:0019783	ubiquitin-like protein-specific protease activity(GO:0019783)
0.1	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.3	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	1.4	GO:0008373	sialyltransferase activity(GO:0008373)
0.1	0.6	GO:0030507	spectrin binding(GO:0030507)
0.1	0.2	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1	0.6	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.1	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
0.1	0.6	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.1	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.1	0.6	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1	0.4	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1	17.2	GO:0005096	GTPase activator activity(GO:0005096)
0.1	8.2	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.1	0.3	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.9	GO:0008234	cysteine-type peptidase activity(GO:0008234)
0.1	1.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	1.3	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.2	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1	0.7	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	0.4	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	0.9	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.1	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	1.6	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.9	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	0.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	1.0	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	0.4	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.1	3.5	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1	0.1	GO:0015923	mannosidase activity(GO:0015923)
0.1	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.1	0.7	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	1.1	GO:0042625	ATPase coupled ion transmembrane transporter activity(GO:0042625)
0.1	3.1	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	0.2	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.1	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.1	0.4	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	0.6	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.1	0.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	19.3	GO:0005525	GTP binding(GO:0005525)
0.1	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	10.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	0.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	1.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	0.1	GO:0016530	metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.1	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.7	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.1	0.4	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.1	0.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	0.1	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.1	0.3	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.4	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.3	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.1	11.6	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.1	0.1	GO:0004803	transposase activity(GO:0004803)
0.1	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	0.1	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.2	GO:0016803	ether hydrolase activity(GO:0016803)
0.1	0.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	0.3	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1	1.3	GO:0034061	DNA polymerase activity(GO:0034061)
0.1	0.5	GO:0051117	ATPase binding(GO:0051117)
0.1	0.1	GO:0035173	histone kinase activity(GO:0035173)
0.1	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.1	1.1	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1	1.3	GO:0016684	peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.1	0.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	0.3	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.9	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.1	0.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.1	0.3	GO:0008494	translation activator activity(GO:0008494)
0.1	20.9	GO:0003723	RNA binding(GO:0003723)
0.1	0.2	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	0.5	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.2	GO:0004966	galanin receptor activity(GO:0004966)
0.1	0.2	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.2	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.2	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1	0.3	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.1	0.4	GO:0019894	kinesin binding(GO:0019894)
0.1	0.9	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.6	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.5	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.0	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.4	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.3	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0043121	neurotrophin receptor activity(GO:0005030) neurotrophin binding(GO:0043121)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.3	GO:0042165	neurotransmitter binding(GO:0042165)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.8	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.0	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.2	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0002039	p53 binding(GO:0002039)
0.0	1.5	GO:0004519	endonuclease activity(GO:0004519)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.2	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.5	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.9	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.3	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.9	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	3.2	GO:0016746	transferase activity, transferring acyl groups(GO:0016746)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	2.3	GO:0003690	double-stranded DNA binding(GO:0003690)
0.0	0.4	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	2.2	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.0	0.6	GO:0004518	nuclease activity(GO:0004518)
0.0	0.3	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	2.8	GO:0003682	chromatin binding(GO:0003682)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	2.4	GO:0016874	ligase activity(GO:0016874)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.6	GO:0005319	lipid transporter activity(GO:0005319)
0.0	0.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.1	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	5.7	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	0.7	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	0.1	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.0	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0005549	odorant binding(GO:0005549)
0.0	0.3	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.3	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	2.0	GO:0016887	ATPase activity(GO:0016887)
0.0	0.7	GO:0016835	carbon-oxygen lyase activity(GO:0016835)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.3	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	1.0	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.9	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.2	GO:0051087	chaperone binding(GO:0051087)
0.0	1.0	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.1	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.0	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.0	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.0	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.1	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.0	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.0	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.0	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0	0.0	GO:0033265	choline binding(GO:0033265)
0.0	4.0	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.1	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
0.0	0.0	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0016866	intramolecular transferase activity(GO:0016866)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	13.9	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.8	46.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.7	5.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.7	17.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.7	2.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.7	5.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.7	8.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.7	4.8	PID IL5 PATHWAY	IL5-mediated signaling events
0.6	9.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.6	4.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6	17.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.6	15.6	PID BCR 5PATHWAY	BCR signaling pathway
0.5	2.7	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.4	3.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.4	3.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4	7.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.4	7.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.4	5.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.4	7.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.4	9.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.4	3.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.4	4.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.4	11.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4	3.9	PID TRAIL PATHWAY	TRAIL signaling pathway
0.4	1.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.3	1.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.3	2.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	2.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.3	1.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.3	3.7	PID IL2 1PATHWAY	IL2-mediated signaling events
0.3	3.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3	5.0	PID IFNG PATHWAY	IFN-gamma pathway
0.3	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.3	8.1	PID FOXO PATHWAY	FoxO family signaling
0.2	0.2	PID S1P S1P2 PATHWAY	S1P2 pathway
0.2	1.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	1.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.2	9.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.2	3.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	2.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.2	0.8	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.2	3.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.2	3.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2	0.8	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2	2.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	2.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2	1.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	0.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.2	3.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.2	0.8	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2	1.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.2	4.0	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	2.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.7	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	2.5	PID MYC PATHWAY	C-MYC pathway
0.1	1.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	3.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	4.2	PID ATR PATHWAY	ATR signaling pathway
0.1	1.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	1.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	0.7	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	5.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	3.6	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	1.7	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	0.6	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	4.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	0.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	3.0	PID LKB1 PATHWAY	LKB1 signaling events
0.1	2.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	3.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	3.1	PID P53 REGULATION PATHWAY	p53 pathway
0.1	1.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	1.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	3.9	PID P73PATHWAY	p73 transcription factor network
0.1	0.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.1	0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	1.7	PID RHOA PATHWAY	RhoA signaling pathway
0.1	1.6	PID ATM PATHWAY	ATM pathway
0.1	1.0	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	1.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	0.9	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	0.8	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	3.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	1.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	3.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	2.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	0.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	0.8	PID BARD1 PATHWAY	BARD1 signaling events
0.1	2.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	1.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	0.7	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	3.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	1.6	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	0.5	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	1.0	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	0.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	0.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	0.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	0.6	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	1.2	PID E2F PATHWAY	E2F transcription factor network
0.0	1.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.4	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.5	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.5	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.0	ST ADRENERGIC	Adrenergic Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	15.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
1.0	12.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.9	9.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.9	13.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.9	2.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.7	0.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.6	10.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.6	7.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.6	14.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.6	1.7	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.5	4.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.5	4.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.5	1.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.5	22.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4	6.7	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.4	4.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.4	6.9	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.4	4.5	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.4	4.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.4	1.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	0.4	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.4	7.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.4	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.4	7.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.4	2.7	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.4	6.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.4	3.8	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	6.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.4	11.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.3	3.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.3	2.0	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.3	1.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.3	8.8	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.3	2.6	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.3	5.6	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3	0.3	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.3	0.6	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.3	0.8	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.3	1.6	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.3	0.3	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.3	0.5	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3	5.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3	4.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.3	3.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.3	1.8	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.3	2.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.2	16.2	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.2	2.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	4.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2	6.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.2	7.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2	1.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	3.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.2	1.2	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.2	0.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.2	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.2	2.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.2	2.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	1.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2	2.9	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2	7.5	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.2	4.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	3.0	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.2	2.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	7.6	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.2	3.1	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.2	6.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	4.8	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.2	1.5	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.2	0.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.2	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2	1.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2	6.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	0.7	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	0.2	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.2	1.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	0.9	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2	3.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	1.7	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.2	1.0	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2	2.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	0.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	0.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2	0.5	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.2	4.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	1.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	0.5	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.2	0.5	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.2	2.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	11.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.2	2.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2	1.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	8.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	6.4	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.1	1.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	1.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	13.5	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1	2.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.7	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.1	1.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.3	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	1.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	11.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.0	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	1.9	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	2.3	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.1	2.5	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.1	1.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	2.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	2.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	1.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	1.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	6.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	1.6	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	2.8	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.1	1.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	0.2	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	1.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	2.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	1.5	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	0.9	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	2.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.1	1.0	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	1.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	2.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	3.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	5.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	0.8	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.1	1.8	REACTOME SIGNALING BY NOTCH	Genes involved in Signaling by NOTCH
0.1	0.4	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.1	2.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	0.8	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	5.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.1	0.3	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.1	0.9	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	4.1	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.1	1.9	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.1	3.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	1.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.5	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.1	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	0.3	REACTOME NUCLEOTIDE EXCISION REPAIR	Genes involved in Nucleotide Excision Repair
0.1	2.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	2.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	0.9	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.2	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1	1.8	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	7.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	0.4	REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.1	1.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	0.2	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1	9.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	0.7	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1	0.9	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	0.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	2.1	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.1	0.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.8	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	1.5	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.1	0.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.0	REACTOME MITOTIC G1 G1 S PHASES	Genes involved in Mitotic G1-G1/S phases
0.1	0.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.5	REACTOME METABOLISM OF NUCLEOTIDES	Genes involved in Metabolism of nucleotides
0.1	0.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	1.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	0.9	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	1.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	3.8	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	0.7	REACTOME MEIOSIS	Genes involved in Meiosis
0.1	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	0.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	1.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.3	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.6	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.1	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.3	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.0	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
0.0	0.0	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.0	2.6	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.0	REACTOME REGULATION OF MITOTIC CELL CYCLE	Genes involved in Regulation of mitotic cell cycle
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.1	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	3.2	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway

Results for ESRRA_ESR2

Z-value: 3.74

Motif logo

Transcription factors associated with ESRRA_ESR2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ESRRA_ESR2 motif across conditions

Conditions sorted by the z-value of the ESRRA_ESR2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRA_ESR2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: