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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ETV6

Z-value: 0.68

Motif logo

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Transcription factors associated with ETV6

Gene Symbol Gene ID Gene Info
ETV6
ENSG00000139083.6 ETV6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ETV6chr12_11922803_11922954174430.2755660.761.7e-02Click!
ETV6chr12_11808723_1180887460100.2901920.732.5e-02Click!
ETV6chr12_11883028_11883179223320.2569670.722.8e-02Click!
ETV6chr12_11877911_11878062274490.2405720.703.6e-02Click!
ETV6chr12_11883469_11883620218910.2583510.694.0e-02Click!

Activity of the ETV6 motif across conditions

Conditions sorted by the z-value of the ETV6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_53693277_53694636 0.37 C12orf10
 chromosome 12 open reading frame 10
 79
 0.58
chr4_185735910_185736201 0.30 RP11-701P16.2
 Uncharacterized protein
 1282
 0.41
chr20_23064192_23064486 0.26 CD93
 CD93 molecule
 2638
 0.25
chr9_126774768_126775305 0.25 LHX2
 LIM homeobox 2
 400
 0.79
chr6_37017654_37018643 0.23 COX6A1P2
 cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
 5541
 0.22
chr13_32621993_32622144 0.23 FRY
 furry homolog (Drosophila)
 12933
 0.22
chr6_33610158_33610417 0.23 ITPR3
 inositol 1,4,5-trisphosphate receptor, type 3
 21126
 0.13
chr2_63274875_63275396 0.22 AC009501.4
289
 0.91
chr12_122075303_122075715 0.22 ORAI1
 ORAI calcium release-activated calcium modulator 1
 10788
 0.17
chr14_24787929_24788080 0.22 LTB4R
 leukotriene B4 receptor
 4098
 0.08
chr17_65430423_65430574 0.22 ENSG00000244610
 .
 22908
 0.12
chr16_17156854_17157148 0.21 CTD-2576D5.4
71360
 0.14
chr15_102182223_102182374 0.21 ENSG00000252614
 .
 6217
 0.18
chr19_457823_457974 0.20 SHC2
 SHC (Src homology 2 domain containing) transforming protein 2
 3098
 0.14
chr8_22571062_22571213 0.20 EGR3
 early growth response 3
 20322
 0.13
chr19_15740026_15740177 0.20 CYP4F3
 cytochrome P450, family 4, subfamily F, polypeptide 3
 11606
 0.18
chr22_39350720_39350871 0.19 APOBEC3A
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
 2039
 0.24
chr15_91459401_91459658 0.19 MAN2A2
 mannosidase, alpha, class 2A, member 2
 3411
 0.11
chr10_99094156_99094718 0.19 FRAT2
 frequently rearranged in advanced T-cell lymphomas 2
 21
 0.6
chr10_121166225_121166376 0.19 GRK5
 G protein-coupled receptor kinase 5
 28351
 0.17
chr1_43397747_43398281 0.19 SLC2A1
 solute carrier family 2 (facilitated glucose transporter), member 1
 1218
 0.47
chr16_89396583_89396806 0.19 ANKRD11
 ankyrin repeat domain 11
 1300
 0.35
chr9_117134390_117135168 0.19 AKNA
 AT-hook transcription factor
 4465
 0.23
chr15_90602890_90603041 0.19 ZNF710
 zinc finger protein 710
 8281
 0.15
chr11_118057234_118057385 0.18 SCN2B
 sodium channel, voltage-gated, type II, beta subunit
 9921
 0.14
chr19_46525700_46525851 0.18 PGLYRP1
 peptidoglycan recognition protein 1
 548
 0.66
chr19_46094450_46094601 0.18 OPA3
 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
 6425
 0.11
chr17_38473365_38473678 0.18 RARA
 retinoic acid receptor, alpha
 1012
 0.41
chrX_18743813_18743964 0.18 PPEF1
 protein phosphatase, EF-hand calcium binding domain 1
 18111
 0.2
chr3_36934586_36934737 0.17 TRANK1
 tetratricopeptide repeat and ankyrin repeat containing 1
 34287
 0.18
chr7_97755628_97755779 0.17 LMTK2
 lemur tyrosine kinase 2
 19506
 0.2
chr1_38465132_38465538 0.17 FHL3
 four and a half LIM domains 3
 5842
 0.13
chr5_10445338_10445751 0.17 ROPN1L
 rhophilin associated tail protein 1-like
 3556
 0.18
chr19_49838375_49839003 0.17 CD37
 CD37 molecule
 5
 0.95
chr1_17519453_17519604 0.16 PADI1
 peptidyl arginine deiminase, type I
 12093
 0.17
chr9_139927070_139927409 0.16 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
 223
 0.78
chr10_72163983_72165283 0.16 EIF4EBP2
 eukaryotic translation initiation factor 4E binding protein 2
 498
 0.77
chr5_50695310_50695461 0.16 ISL1
 ISL LIM homeobox 1
 15879
 0.22
chr19_50143768_50144112 0.16 RRAS
 related RAS viral (r-ras) oncogene homolog
 482
 0.54
chr4_31024444_31024595 0.16 RP11-619J20.1
228927
 0.02
chr11_64624166_64624317 0.16 CDC42BPG
 CDC42 binding protein kinase gamma (DMPK-like)
 12200
 0.1
chr2_119130108_119130259 0.16 INSIG2
 insulin induced gene 2
 284133
 0.01
chr22_19879311_19879851 0.16 GNB1L
 guanine nucleotide binding protein (G protein), beta polypeptide 1-like
 37119
 0.1
chr19_8645617_8645768 0.16 AC130469.2
352
 0.8
chr19_19483852_19484190 0.16 GATAD2A
 GATA zinc finger domain containing 2A
 12614
 0.13
chr2_8627682_8628105 0.16 AC011747.7
188003
 0.03
chr21_34442470_34442979 0.16 OLIG1
 oligodendrocyte transcription factor 1
 274
 0.77
chr5_137090212_137090730 0.15 HNRNPA0
 heterogeneous nuclear ribonucleoprotein A0
 432
 0.85
chr6_28227027_28227486 0.15 NKAPL
 NFKB activating protein-like
 158
 0.61
chr20_42166672_42166823 0.15 L3MBTL1
 l(3)mbt-like 1 (Drosophila)
 9400
 0.15
chr9_127266363_127266826 0.15 NR5A1
 nuclear receptor subfamily 5, group A, member 1
 2920
 0.28
chr22_42832160_42832442 0.15 NFAM1
 NFAT activating protein with ITAM motif 1
 3900
 0.23
chr16_10479736_10481071 0.15 ATF7IP2
 activating transcription factor 7 interacting protein 2
 485
 0.83
chr19_48833533_48834100 0.15 EMP3
 epithelial membrane protein 3
 4951
 0.12
chr16_28505762_28506015 0.15 APOBR
 apolipoprotein B receptor
 82
 0.93
chr4_40623487_40623692 0.15 RBM47
 RNA binding motif protein 47
 8292
 0.27
chr9_132646855_132647649 0.15 FNBP1
 formin binding protein 1
 34337
 0.12
chr21_36077269_36077677 0.15 CLIC6
 chloride intracellular channel 6
 35785
 0.17
chr14_103588344_103588755 0.15 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
 1249
 0.43
chr1_87244034_87244185 0.15 SH3GLB1
 SH3-domain GRB2-like endophilin B1
 73531
 0.09
chr15_101708121_101708357 0.15 RP11-505E24.2
81968
 0.08
chr17_40993833_40993984 0.15 AOC2
 amine oxidase, copper containing 2 (retina-specific)
 2709
 0.12
chr3_133293335_133294350 0.15 CDV3
 CDV3 homolog (mouse)
 350
 0.89
chr16_4909761_4909912 0.15 UBN1
 ubinuclein 1
 7620
 0.14
chr17_73584494_73585142 0.15 MYO15B
 myosin XVB pseudogene
 2040
 0.21
chr19_55084758_55085279 0.14 LILRA2
 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
 200
 0.63
chr17_45772156_45772908 0.14 TBKBP1
 TBK1 binding protein 1
 98
 0.95
chr15_30213515_30213794 0.14 TJP1
 tight junction protein 1
 47414
 0.15
chr11_62767141_62767292 0.14 SLC22A6
 solute carrier family 22 (organic anion transporter), member 6
 14761
 0.14
chr21_36217976_36218127 0.14 RUNX1
 runt-related transcription factor 1
 41429
 0.2
chr1_205717555_205718736 0.14 NUCKS1
 nuclear casein kinase and cyclin-dependent kinase substrate 1
 1259
 0.38
chr5_112539683_112539834 0.14 MCC
 mutated in colorectal cancers
 30616
 0.23
chr14_23588365_23588516 0.14 CEBPE
 CCAAT/enhancer binding protein (C/EBP), epsilon
 385
 0.75
chr20_6947669_6947820 0.14 ENSG00000251833
 .
 106083
 0.08
chr16_9207976_9208127 0.14 RP11-473I1.10
6953
 0.16
chr1_32123629_32123780 0.14 RP11-73M7.6
845
 0.49
chr11_8190407_8190734 0.14 RIC3
 RIC3 acetylcholine receptor chaperone
 2
 0.98
chr1_12244133_12244323 0.14 ENSG00000263676
 .
 7542
 0.16
chr19_4374031_4374264 0.14 SH3GL1
 SH3-domain GRB2-like 1
 6142
 0.08
chr6_129944528_129944679 0.14 ARHGAP18
 Rho GTPase activating protein 18
 86767
 0.09
chr1_22351811_22352015 0.14 ENSG00000201273
 .
 14435
 0.09
chr14_70111468_70111619 0.14 KIAA0247
 KIAA0247
 33230
 0.18
chr16_84766426_84766761 0.13 USP10
 ubiquitin specific peptidase 10
 32947
 0.16
chr1_223306949_223307134 0.13 TLR5
 toll-like receptor 5
 1057
 0.67
chr16_69373556_69374479 0.13 NIP7
 NIP7, nucleolar pre-rRNA processing protein
 157
 0.76
chr8_121457410_121457992 0.13 MTBP
 Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
 35
 0.54
chr21_34905254_34905405 0.13 GART
 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
 9091
 0.13
chr2_7571269_7571803 0.13 ENSG00000221255
 .
 145436
 0.05
chr20_56048279_56048430 0.13 CTCFL
 CCCTC-binding factor (zinc finger protein)-like
 50959
 0.11
chr6_130341588_130342312 0.13 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
 248
 0.96
chr16_85786290_85786441 0.13 C16orf74
 chromosome 16 open reading frame 74
 1630
 0.24
chr3_47418814_47418965 0.13 RP11-708J19.1
3600
 0.2
chr2_28817013_28817303 0.13 PLB1
 phospholipase B1
 7628
 0.24
chr19_56166514_56167932 0.13 U2AF2
 U2 small nuclear RNA auxiliary factor 2
 792
 0.34
chr11_19990149_19990300 0.13 NAV2-AS3
 NAV2 antisense RNA 3
 12659
 0.24
chr1_46859625_46860587 0.13 FAAH
 fatty acid amide hydrolase
 169
 0.95
chr3_15332172_15332523 0.13 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 14795
 0.14
chr8_61764729_61764880 0.13 RP11-33I11.2
42639
 0.2
chr19_1754756_1754961 0.13 ONECUT3
 one cut homeobox 3
 2486
 0.2
chr19_12902481_12903520 0.13 JUNB
 jun B proto-oncogene
 690
 0.39
chr12_4380012_4380209 0.13 CCND2
 cyclin D2
 2828
 0.22
chr3_167812746_167813857 0.13 GOLIM4
 golgi integral membrane protein 4
 169
 0.97
chr4_7060277_7060428 0.13 TADA2B
 transcriptional adaptor 2B
 5272
 0.13
chr19_17439012_17439348 0.13 ANO8
 anoctamin 8
 6458
 0.08
chr12_7055489_7056183 0.12 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
 63
 0.9
chr21_16429371_16429522 0.12 NRIP1
 nuclear receptor interacting protein 1
 7680
 0.28
chr7_6066625_6066776 0.12 EIF2AK1
 eukaryotic translation initiation factor 2-alpha kinase 1
 517
 0.61
chr11_130030115_130030717 0.12 ST14
 suppression of tumorigenicity 14 (colon carcinoma)
 959
 0.66
chr3_49943448_49943849 0.12 CTD-2330K9.3
 Uncharacterized protein
 2228
 0.16
chr5_139926895_139927116 0.12 EIF4EBP3
 eukaryotic translation initiation factor 4E binding protein 3
 246
 0.82
chr2_38151836_38153080 0.12 RMDN2
 regulator of microtubule dynamics 2
 4
 0.99
chr16_70487949_70488475 0.12 FUK
 fucokinase
 112
 0.94
chr11_57566897_57567048 0.12 CTNND1
 catenin (cadherin-associated protein), delta 1
 7941
 0.18
chr4_56261758_56262564 0.12 TMEM165
 transmembrane protein 165
 31
 0.65
chr6_225379_225671 0.12 DUSP22
 dual specificity phosphatase 22
 66105
 0.15
chr1_161008749_161009060 0.12 TSTD1
 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
 124
 0.91
chr2_242674070_242675162 0.12 AC114730.8
297
 0.65
chr16_23132061_23132212 0.12 USP31
 ubiquitin specific peptidase 31
 28455
 0.2
chr19_38756015_38756259 0.12 SPINT2
 serine peptidase inhibitor, Kunitz type, 2
 159
 0.9
chr17_57408824_57410302 0.12 YPEL2
 yippee-like 2 (Drosophila)
 500
 0.78
chr12_94519902_94520172 0.12 PLXNC1
 plexin C1
 22462
 0.21
chr16_11707122_11707273 0.12 LITAF
 lipopolysaccharide-induced TNF factor
 14841
 0.18
chr5_171840008_171840159 0.12 ENSG00000216127
 .
 26675
 0.19
chr17_29149849_29150048 0.12 CRLF3
 cytokine receptor-like factor 3
 1741
 0.25
chr9_137258561_137258730 0.12 ENSG00000263897
 .
 12612
 0.24
chr7_37487305_37488000 0.12 ELMO1
 engulfment and cell motility 1
 901
 0.61
chr22_35772700_35773071 0.12 HMOX1
 heme oxygenase (decycling) 1
 3469
 0.23
chr1_156630677_156631393 0.12 RP11-284F21.7
181
 0.89
chr2_54643569_54643720 0.12 SPTBN1
 spectrin, beta, non-erythrocytic 1
 39778
 0.18
chr11_128554784_128555228 0.11 RP11-744N12.3
1317
 0.34
chr17_54910275_54910729 0.11 C17orf67
 chromosome 17 open reading frame 67
 754
 0.45
chr10_22540455_22541288 0.11 EBLN1
 endogenous Bornavirus-like nucleoprotein 1
 41921
 0.14
chr13_37005266_37006411 0.11 CCNA1
 cyclin A1
 129
 0.97
chr12_10205099_10205456 0.11 CLEC9A
 C-type lectin domain family 9, member A
 22001
 0.1
chr14_107081796_107081947 0.11 IGHV4-59
 immunoglobulin heavy variable 4-59
 1854
 0.07
chr17_49337942_49338261 0.11 UTP18
 UTP18 small subunit (SSU) processome component homolog (yeast)
 212
 0.82
chr1_154980554_154980872 0.11 ZBTB7B
 zinc finger and BTB domain containing 7B
 5418
 0.08
chr6_130848326_130848477 0.11 ENSG00000202438
 .
 46856
 0.17
chr19_51522714_51522865 0.11 KLK10
 kallikrein-related peptidase 10
 231
 0.81
chr22_33636979_33637130 0.11 RP1-302D9.3
77005
 0.1
chr9_109649535_109649686 0.11 ZNF462
 zinc finger protein 462
 24163
 0.19
chr17_36715319_36715684 0.11 SRCIN1
 SRC kinase signaling inhibitor 1
 4159
 0.19
chr7_74277653_74277804 0.11 GTF2IRD2
 GTF2I repeat domain containing 2
 9881
 0.18
chr6_12483851_12484268 0.11 ENSG00000223321
 .
 77046
 0.12
chr14_100842881_100843420 0.11 WARS
 tryptophanyl-tRNA synthetase
 8
 0.78
chr19_51631094_51631245 0.11 SIGLEC9
 sialic acid binding Ig-like lectin 9
 882
 0.38
chr13_24845503_24846606 0.11 SPATA13
 spermatogenesis associated 13
 773
 0.61
chr9_95878549_95878700 0.11 NINJ1
 ninjurin 1
 17946
 0.14
chr19_911654_912010 0.11 R3HDM4
 R3H domain containing 4
 1399
 0.21
chr11_1328574_1328800 0.11 TOLLIP
 toll interacting protein
 2162
 0.23
chr19_10380429_10381098 0.11 ICAM1
 intercellular adhesion molecule 1
 748
 0.39
chr6_130702998_130703205 0.11 TMEM200A
 transmembrane protein 200A
 16222
 0.2
chr11_129695482_129695633 0.11 TMEM45B
 transmembrane protein 45B
 9843
 0.27
chr12_13251108_13251431 0.11 GSG1
 germ cell associated 1
 2529
 0.3
chr1_24069439_24069920 0.11 TCEB3
 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
 34
 0.96
chr1_230262662_230262881 0.11 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 59753
 0.13
chr2_149303386_149303537 0.11 MBD5
 methyl-CpG binding domain protein 5
 77167
 0.11
chr7_150329208_150329551 0.11 GIMAP6
 GTPase, IMAP family member 6
 55
 0.98
chr16_75058643_75058911 0.11 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 22582
 0.18
chr4_140481827_140481978 0.11 RP11-342I1.2
3949
 0.22
chr20_61559769_61560616 0.10 DIDO1
 death inducer-obliterator 1
 2337
 0.23
chr6_108349048_108349199 0.10 ENSG00000238490
 .
 32899
 0.14
chr1_46073171_46073322 0.10 NASP
 nuclear autoantigenic sperm protein (histone-binding)
 5595
 0.17
chr11_60934798_60934949 0.10 VPS37C
 vacuolar protein sorting 37 homolog C (S. cerevisiae)
 5784
 0.17
chr9_132406808_132406959 0.10 ASB6
 ankyrin repeat and SOCS box containing 6
 2439
 0.18
chr16_53128120_53128271 0.10 CHD9
 chromodomain helicase DNA binding protein 9
 4877
 0.27
chr14_35809151_35809404 0.10 PSMA6
 proteasome (prosome, macropain) subunit, alpha type, 6
 29238
 0.18
chr14_66602242_66602393 0.10 ENSG00000200860
 .
 42036
 0.2
chr2_219496883_219497034 0.10 RP11-548H3.1
1779
 0.19
chr2_65039482_65039633 0.10 ENSG00000239891
 .
 4955
 0.21
chr1_17508352_17508670 0.10 PADI1
 peptidyl arginine deiminase, type I
 23110
 0.15
chr15_99105917_99106068 0.10 FAM169B
 family with sequence similarity 169, member B
 48381
 0.16
chr7_48136018_48136265 0.10 UPP1
 uridine phosphorylase 1
 7168
 0.24
chr4_15004104_15004915 0.10 CPEB2
 cytoplasmic polyadenylation element binding protein 2
 211
 0.97
chr20_45946936_45948261 0.10 AL031666.2
 HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
 352
 0.82
chr7_157130148_157131060 0.10 DNAJB6
 DnaJ (Hsp40) homolog, subfamily B, member 6
 367
 0.9
chr17_77778016_77778167 0.10 CBX8
 chromobox homolog 8
 2759
 0.18
chr11_46698234_46698478 0.10 ATG13
 autophagy related 13
 12806
 0.13
chr19_8559121_8559517 0.10 PRAM1
 PML-RARA regulated adaptor molecule 1
 8176
 0.12
chr10_91055374_91055594 0.10 IFIT2
 interferon-induced protein with tetratricopeptide repeats 2
 6228
 0.15
chr12_22840824_22841065 0.10 ETNK1
 ethanolamine kinase 1
 62653
 0.13
chr7_66146644_66146983 0.10 RP4-756H11.3
27240
 0.16
chr18_47003055_47003217 0.10 RP11-110H1.4
9383
 0.08
chr22_40882106_40882345 0.10 MKL1
 megakaryoblastic leukemia (translocation) 1
 22787
 0.15
chr8_61851903_61852054 0.10 CLVS1
 clavesin 1
 117739
 0.06
chr17_46048416_46049087 0.10 CDK5RAP3
 CDK5 regulatory subunit associated protein 3
 234
 0.85
chr15_91427302_91427634 0.10 FES
 feline sarcoma oncogene
 174
 0.9
chr13_32607825_32607976 0.10 FRY-AS1
 FRY antisense RNA 1
 2124
 0.32
chr11_554769_555059 0.10 RP11-496I9.1
2681
 0.11
chr12_50925398_50925549 0.10 DIP2B
 DIP2 disco-interacting protein 2 homolog B (Drosophila)
 26583
 0.19
chrX_20283128_20284271 0.10 RPS6KA3
 ribosomal protein S6 kinase, 90kDa, polypeptide 3
 1061
 0.63
chr2_101911542_101911693 0.10 RNF149
 ring finger protein 149
 13541
 0.16
chr19_48827788_48827939 0.10 EMP3
 epithelial membrane protein 3
 719
 0.53
chr1_161197360_161197771 0.10 ENSG00000263548
 .
 589
 0.45
chr15_85278174_85278822 0.09 ZNF592
 zinc finger protein 592
 13368
 0.12
chr3_148995184_148995347 0.09 RP11-206M11.7
7304
 0.21
chr1_209979523_209979948 0.09 IRF6
 interferon regulatory factor 6
 270
 0.89
chr6_127664293_127665233 0.09 ECHDC1
 enoyl CoA hydratase domain containing 1
 9
 0.98
chr1_55266980_55267187 0.09 TTC22
 tetratricopeptide repeat domain 22
 143
 0.94
chr11_118122819_118123419 0.09 MPZL3
 myelin protein zero-like 3
 54
 0.96

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ETV6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0052257 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0072124 glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0046471 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:1902808 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.0 GO:0022009 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.0 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.0 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.0 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G