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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EVX2

Z-value: 0.60

Motif logo

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Transcription factors associated with EVX2

Gene Symbol Gene ID Gene Info
ENSG00000174279.4 EVX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
EVX2chr2_176932607_176932906158850.098539-0.817.9e-03Click!
EVX2chr2_176931780_176932252166250.098417-0.561.2e-01Click!
EVX2chr2_176952907_17695313643800.100133-0.551.3e-01Click!
EVX2chr2_176943993_17694419545470.110379-0.541.3e-01Click!
EVX2chr2_176932269_176932561162260.098484-0.472.0e-01Click!

Activity of the EVX2 motif across conditions

Conditions sorted by the z-value of the EVX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_74964898_74965186 0.44 ENSG00000267568
.
137
0.97
chr1_234544831_234544982 0.39 COA6
cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
35459
0.12
chr2_193992778_193992929 0.36 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
932418
0.0
chr11_128589269_128589524 0.36 SENCR
smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
23478
0.17
chr1_236284065_236284436 0.35 GPR137B
G protein-coupled receptor 137B
21582
0.19
chr12_131796680_131796831 0.34 ENSG00000212251
.
12459
0.23
chr4_144312492_144312643 0.32 GAB1
GRB2-associated binding protein 1
96
0.98
chr7_41921705_41921953 0.31 AC005027.3

176896
0.03
chr3_32994754_32995260 0.29 CCR4
chemokine (C-C motif) receptor 4
1941
0.43
chr1_226919798_226919959 0.29 ITPKB
inositol-trisphosphate 3-kinase B
5281
0.26
chr16_50776896_50777610 0.29 RP11-327F22.1

527
0.39
chr9_95790679_95791025 0.29 FGD3
FYVE, RhoGEF and PH domain containing 3
13510
0.18
chrX_78403286_78403508 0.29 GPR174
G protein-coupled receptor 174
23072
0.28
chr6_25041553_25042305 0.29 RP3-425P12.5

138
0.72
chr12_47600587_47601314 0.28 PCED1B
PC-esterase domain containing 1B
9102
0.22
chr15_52023462_52024365 0.28 LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
6405
0.15
chr7_115668295_115668446 0.27 TFEC
transcription factor EC
2425
0.43
chr4_143321296_143321548 0.27 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
30990
0.26
chr5_126094279_126094440 0.27 ENSG00000252185
.
3250
0.29
chr16_79652209_79652360 0.26 MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
17673
0.26
chr16_17164825_17164976 0.26 CTD-2576D5.4

63461
0.16
chr12_64798382_64799443 0.25 XPOT
exportin, tRNA
86
0.97
chr1_206646546_206646697 0.25 IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
2783
0.21
chr14_99703180_99703331 0.25 AL109767.1

26030
0.19
chr20_47440971_47441122 0.24 PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
3374
0.34
chr1_28975271_28975442 0.24 ENSG00000270103
.
244
0.88
chr4_105887659_105887892 0.24 ENSG00000251906
.
8044
0.31
chr13_21050204_21050392 0.23 ENSG00000263978
.
42313
0.15
chr15_70384069_70384220 0.23 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
2980
0.31
chr12_27150397_27150548 0.22 TM7SF3
transmembrane 7 superfamily member 3
2271
0.24
chr13_99957828_99957979 0.22 GPR183
G protein-coupled receptor 183
1756
0.38
chr1_186291714_186291865 0.22 ENSG00000202025
.
10729
0.17
chr22_40322756_40322951 0.22 GRAP2
GRB2-related adaptor protein 2
212
0.93
chr10_112632655_112633305 0.21 PDCD4-AS1
PDCD4 antisense RNA 1
989
0.38
chr18_9404580_9404814 0.21 TWSG1
twisted gastrulation BMP signaling modulator 1
69849
0.08
chr7_37011253_37011404 0.20 ELMO1
engulfment and cell motility 1
13337
0.2
chr1_150294067_150294674 0.20 PRPF3
pre-mRNA processing factor 3
368
0.78
chr4_74571443_74571594 0.19 IL8
interleukin 8
34705
0.18
chr20_47441337_47441845 0.19 PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
2829
0.36
chr2_100388320_100388562 0.19 AFF3
AF4/FMR2 family, member 3
193609
0.03
chr19_16770752_16770951 0.19 CTC-429P9.4
Small integral membrane protein 7; Uncharacterized protein
64
0.53
chr6_36008402_36008553 0.19 MAPK14
mitogen-activated protein kinase 14
11611
0.19
chr8_131954085_131954236 0.19 RP11-737F9.1

6505
0.26
chr10_70850849_70851349 0.18 SRGN
serglycin
3225
0.25
chr1_90101335_90101580 0.18 LRRC8C
leucine rich repeat containing 8 family, member C
2826
0.22
chr14_93552039_93552233 0.18 ITPK1-AS1
ITPK1 antisense RNA 1
18339
0.18
chr10_54463336_54463751 0.17 RP11-556E13.1

51626
0.16
chr8_110619590_110619741 0.17 SYBU
syntabulin (syntaxin-interacting)
639
0.72
chr4_139635357_139635508 0.17 ENSG00000238971
.
97488
0.08
chrX_38728231_38728382 0.17 MID1IP1-AS1
MID1IP1 antisense RNA 1
65170
0.13
chr1_225610206_225610357 0.17 LBR
lamin B receptor
5318
0.2
chr5_154465051_154465202 0.16 ENSG00000221131
.
60766
0.13
chr4_154412529_154412680 0.16 KIAA0922
KIAA0922
25103
0.22
chr7_83932213_83932364 0.16 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
107527
0.08
chr6_143263290_143263441 0.16 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
2973
0.34
chr6_131948545_131949340 0.16 MED23
mediator complex subunit 23
258
0.77
chr9_72745702_72745853 0.16 MAMDC2-AS1
MAMDC2 antisense RNA 1
17001
0.22
chr3_16883621_16883873 0.16 PLCL2
phospholipase C-like 2
42705
0.19
chr4_1005974_1006310 0.16 FGFRL1
fibroblast growth factor receptor-like 1
97
0.95
chr5_75600050_75600201 0.16 RP11-466P24.6

7162
0.3
chr1_112283056_112283209 0.15 FAM212B-AS1
FAM212B antisense RNA 1
657
0.55
chr16_53133173_53134292 0.15 CHD9
chromodomain helicase DNA binding protein 9
660
0.77
chr20_56286148_56286403 0.15 PMEPA1
prostate transmembrane protein, androgen induced 1
266
0.95
chr7_17039488_17039788 0.15 AGR3
anterior gradient 3
118027
0.06
chr22_50908966_50909262 0.15 SBF1
SET binding factor 1
4257
0.1
chr14_39736543_39737240 0.15 CTAGE5
CTAGE family, member 5
273
0.72
chrX_23969833_23969984 0.15 CXorf58
chromosome X open reading frame 58
41408
0.14
chr1_90290694_90290845 0.15 LRRC8D
leucine rich repeat containing 8 family, member D
3289
0.28
chr18_46455022_46455234 0.15 SMAD7
SMAD family member 7
19747
0.23
chr4_84031409_84031639 0.15 PLAC8
placenta-specific 8
528
0.83
chr20_34330600_34331178 0.14 RBM39
RNA binding motif protein 39
655
0.59
chr17_27252886_27253120 0.14 RP11-20B24.5

290
0.78
chr1_10516682_10516833 0.14 RP5-1113E3.3

1855
0.2
chr5_110560941_110561277 0.14 CAMK4
calcium/calmodulin-dependent protein kinase IV
1325
0.51
chr3_150258880_150259179 0.14 SERP1
stress-associated endoplasmic reticulum protein 1
5257
0.22
chr13_83262553_83263100 0.14 ENSG00000222791
.
609476
0.0
chr14_22993528_22993679 0.13 TRAJ15
T cell receptor alpha joining 15
4977
0.12
chr15_43985556_43986365 0.13 CKMT1A
creatine kinase, mitochondrial 1A
109
0.93
chr15_75080868_75081404 0.13 ENSG00000264386
.
38
0.76
chr11_23886778_23886929 0.13 ENSG00000252519
.
15529
0.31
chr4_41884194_41884831 0.13 TMEM33
transmembrane protein 33
52625
0.14
chr14_70102783_70102934 0.13 KIAA0247
KIAA0247
24545
0.21
chr14_65192350_65192501 0.13 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
1926
0.38
chr15_43885730_43886468 0.13 CKMT1B
creatine kinase, mitochondrial 1B
42
0.95
chr13_40229560_40229742 0.12 COG6
component of oligomeric golgi complex 6
113
0.96
chr16_50623254_50623506 0.12 RP11-401P9.6

24215
0.14
chr19_16482178_16482409 0.12 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
9529
0.15
chr17_9313239_9313390 0.12 AC087501.1

42200
0.15
chr7_6114490_6114641 0.12 ENSG00000264605
.
8171
0.11
chr12_94805998_94806149 0.12 CCDC41
coiled-coil domain containing 41
47649
0.14
chr1_21349011_21349508 0.12 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
28136
0.19
chr7_30388343_30388494 0.12 ENSG00000207771
.
59008
0.11
chr4_166361643_166362016 0.12 CPE
carboxypeptidase E
22451
0.23
chr1_30417491_30417642 0.12 ENSG00000222787
.
59817
0.17
chr6_79788386_79788977 0.12 PHIP
pleckstrin homology domain interacting protein
728
0.79
chr14_22747289_22747440 0.12 ENSG00000238634
.
136477
0.04
chr21_15917916_15918619 0.12 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
395
0.89
chr2_112368119_112368270 0.11 ENSG00000266063
.
160517
0.04
chr16_6001852_6002003 0.11 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
67168
0.13
chr15_100881986_100882218 0.11 ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
108
0.98
chr17_64297613_64298278 0.11 PRKCA
protein kinase C, alpha
999
0.57
chr4_146101952_146102435 0.11 OTUD4
OTU domain containing 4
880
0.65
chr4_26887523_26887909 0.11 STIM2
stromal interaction molecule 2
24635
0.21
chr2_54798401_54798574 0.11 SPTBN1
spectrin, beta, non-erythrocytic 1
12956
0.19
chr6_130391698_130391967 0.11 L3MBTL3
l(3)mbt-like 3 (Drosophila)
50130
0.15
chr5_108208713_108208864 0.11 ENSG00000207404
.
18350
0.23
chr1_150549248_150549415 0.11 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
2675
0.12
chr17_10601145_10601947 0.11 ADPRM
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
635
0.41
chrX_78200973_78201449 0.10 P2RY10
purinergic receptor P2Y, G-protein coupled, 10
293
0.95
chr10_45389082_45389233 0.10 TMEM72
transmembrane protein 72
17491
0.16
chr5_134370433_134370584 0.10 PITX1
paired-like homeodomain 1
5
0.97
chrX_131614340_131615550 0.10 MBNL3
muscleblind-like splicing regulator 3
8098
0.3
chr1_25887536_25887687 0.10 LDLRAP1
low density lipoprotein receptor adaptor protein 1
17540
0.19
chr14_49374188_49374339 0.10 ENSG00000251824
.
36454
0.24
chr1_200987607_200987758 0.10 KIF21B
kinesin family member 21B
4854
0.21
chr14_99723235_99723386 0.10 AL109767.1

5975
0.23
chr1_99843003_99843154 0.10 LPPR4
Lipid phosphate phosphatase-related protein type 4
78658
0.12
chr8_70622919_70623070 0.10 RP11-102F4.2

2631
0.31
chr2_235359483_235359634 0.10 ARL4C
ADP-ribosylation factor-like 4C
45686
0.21
chr12_1613703_1614089 0.09 WNT5B
wingless-type MMTV integration site family, member 5B
25161
0.21
chr1_1710161_1710908 0.09 NADK
NAD kinase
305
0.86
chr11_16759613_16759958 0.09 C11orf58
chromosome 11 open reading frame 58
163
0.97
chr2_38822967_38823118 0.09 HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
4126
0.22
chrX_78620829_78620980 0.09 ITM2A
integral membrane protein 2A
1952
0.51
chr6_134499074_134500065 0.09 SGK1
serum/glucocorticoid regulated kinase 1
526
0.8
chr12_54891959_54892179 0.09 NCKAP1L
NCK-associated protein 1-like
499
0.73
chr7_105912156_105912307 0.09 NAMPT
nicotinamide phosphoribosyltransferase
13136
0.21
chr10_33425320_33425471 0.09 ENSG00000263576
.
37831
0.16
chr19_13049368_13049753 0.09 CALR
calreticulin
101
0.89
chr8_87357008_87357171 0.09 WWP1
WW domain containing E3 ubiquitin protein ligase 1
2122
0.42
chr17_75456326_75456913 0.09 SEPT9
septin 9
4171
0.18
chr15_31690130_31690281 0.09 KLF13
Kruppel-like factor 13
31848
0.24
chr1_108505298_108505449 0.09 VAV3-AS1
VAV3 antisense RNA 1
1692
0.35
chr22_21357082_21357447 0.09 THAP7-AS1
THAP7 antisense RNA 1
767
0.29
chr17_16724813_16724964 0.09 AC022596.6

918
0.46
chr6_26312991_26313348 0.09 HIST1H4H
histone cluster 1, H4h
27407
0.07
chr2_162095067_162095304 0.09 TANK
TRAF family member-associated NFKB activator
7488
0.21
chr10_70230757_70231440 0.09 DNA2
DNA replication helicase/nuclease 2
545
0.71
chr6_30180418_30180721 0.09 TRIM26
tripartite motif containing 26
574
0.68
chr13_48975408_48975569 0.09 LPAR6
lysophosphatidic acid receptor 6
25555
0.23
chr2_103506378_103506656 0.09 TMEM182
transmembrane protein 182
128045
0.06
chr1_121159975_121160126 0.09 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
224113
0.02
chr13_46627012_46627449 0.09 CPB2-AS1
CPB2 antisense RNA 1
193
0.67
chr9_80524074_80524374 0.09 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
86309
0.1
chr1_204548801_204548952 0.09 ENSG00000200408
.
17227
0.14
chr11_117151480_117151734 0.09 BACE1
beta-site APP-cleaving enzyme 1
14594
0.13
chr3_18472261_18472412 0.08 SATB1
SATB homeobox 1
4409
0.24
chr17_78965248_78965600 0.08 CHMP6
charged multivesicular body protein 6
26
0.96
chr7_84685147_84685298 0.08 SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
66029
0.15
chr1_200332191_200332460 0.08 ZNF281
zinc finger protein 281
46795
0.19
chr7_36243067_36243218 0.08 AC007327.5

27574
0.18
chr1_158786969_158787120 0.08 MNDA
myeloid cell nuclear differentiation antigen
14063
0.17
chr10_124269771_124269922 0.08 HTRA1
HtrA serine peptidase 1
3639
0.26
chr10_105211471_105211777 0.08 CALHM2
calcium homeostasis modulator 2
451
0.57
chr12_866633_866784 0.08 WNK1
WNK lysine deficient protein kinase 1
3976
0.25
chr10_90752530_90752985 0.08 ACTA2
actin, alpha 2, smooth muscle, aorta
1610
0.28
chr1_100820231_100820573 0.08 CDC14A
cell division cycle 14A
1897
0.33
chr2_216877074_216877561 0.08 MREG
melanoregulin
1029
0.61
chr11_114129890_114130041 0.08 NNMT
nicotinamide N-methyltransferase
1412
0.51
chr11_88068800_88069370 0.08 CTSC
cathepsin C
1816
0.49
chr2_99552897_99553419 0.08 KIAA1211L
KIAA1211-like
436
0.88
chr10_7453140_7453326 0.08 SFMBT2
Scm-like with four mbt domains 2
215
0.96
chr6_41855450_41855601 0.08 USP49
ubiquitin specific peptidase 49
458
0.75
chr5_173293780_173293931 0.08 CPEB4
cytoplasmic polyadenylation element binding protein 4
21428
0.25
chr6_130030490_130031674 0.08 ARHGAP18
Rho GTPase activating protein 18
288
0.94
chr10_63753889_63754171 0.08 ARID5B
AT rich interactive domain 5B (MRF1-like)
54940
0.15
chr15_34875013_34876331 0.08 GOLGA8B
golgin A8 family, member B
99
0.96
chr14_91091040_91091191 0.08 TTC7B
tetratricopeptide repeat domain 7B
6748
0.2
chr8_38237822_38238929 0.08 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
36
0.96
chr10_77308241_77308392 0.08 ENSG00000207583
.
3900
0.31
chr10_46075820_46076565 0.08 MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
13747
0.25
chr2_198572065_198572426 0.08 MARS2
methionyl-tRNA synthetase 2, mitochondrial
2158
0.3
chr2_80472785_80472936 0.08 ENSG00000221179
.
1112
0.61
chr11_128582862_128583013 0.08 SENCR
smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
17019
0.17
chr1_160614457_160614608 0.08 SLAMF1
signaling lymphocytic activation molecule family member 1
2279
0.26
chr6_90868813_90868964 0.07 BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
137573
0.04
chr10_173487_173638 0.07 ZMYND11
zinc finger, MYND-type containing 11
6843
0.24
chr7_6654683_6655004 0.07 ZNF853
zinc finger protein 853
405
0.77
chr3_124774787_124775424 0.07 HEG1
heart development protein with EGF-like domains 1
303
0.88
chr14_88471433_88472132 0.07 GPR65
G protein-coupled receptor 65
314
0.88
chr13_91999115_91999698 0.07 ENSG00000215417
.
3453
0.35
chr2_136876136_136876323 0.07 CXCR4
chemokine (C-X-C motif) receptor 4
494
0.87
chr17_25622078_25622646 0.07 WSB1
WD repeat and SOCS box containing 1
990
0.48
chr6_30923060_30923530 0.07 HCG21
HLA complex group 21 (non-protein coding)
656
0.5
chr19_55656842_55656993 0.07 TNNT1
troponin T type 1 (skeletal, slow)
1393
0.22
chr1_111420872_111421052 0.07 CD53
CD53 molecule
5186
0.22
chr18_11852846_11853378 0.07 RP11-78A19.3

362
0.77
chr5_148931227_148931707 0.07 ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
43
0.88
chr19_6481304_6482171 0.07 DENND1C
DENN/MADD domain containing 1C
27
0.95
chr17_39742070_39742221 0.07 KRT14
keratin 14
1028
0.36
chr14_32672268_32672419 0.07 ENSG00000202337
.
132
0.94
chr8_97273295_97273764 0.07 MTERFD1
MTERF domain containing 1
287
0.6
chr19_12888779_12888973 0.07 HOOK2
hook microtubule-tethering protein 2
350
0.68
chr7_5594421_5594572 0.07 CTB-161C1.1

1866
0.25
chr10_75686047_75686198 0.07 C10orf55
chromosome 10 open reading frame 55
3587
0.18
chr16_88937052_88937336 0.07 PABPN1L
poly(A) binding protein, nuclear 1-like (cytoplasmic)
4126
0.12
chr7_139476140_139477008 0.07 HIPK2
homeodomain interacting protein kinase 2
943
0.52
chrX_35788537_35788688 0.07 MAGEB16
melanoma antigen family B, 16
27847
0.25
chr15_50557147_50557298 0.07 HDC
histidine decarboxylase
641
0.66
chr6_154568354_154568864 0.07 IPCEF1
interaction protein for cytohesin exchange factors 1
53
0.99

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of EVX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.0 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors