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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FIGLA

Z-value: 0.20

Motif logo

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Transcription factors associated with FIGLA

Gene Symbol Gene ID Gene Info
ENSG00000183733.6 FIGLA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
FIGLAchr2_71016684_710168819930.490381-0.713.2e-02Click!
FIGLAchr2_71017218_710176863230.865016-0.225.7e-01Click!
FIGLAchr2_71016964_710171697090.6273640.029.6e-01Click!

Activity of the FIGLA motif across conditions

Conditions sorted by the z-value of the FIGLA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_86126252_86126683 0.05 RP11-815J21.2

3058
0.23
chr17_78748885_78749036 0.04 RP11-28G8.1

30472
0.2
chr9_132802183_132802428 0.04 FNBP1
formin binding protein 1
3136
0.26
chr2_178217813_178218079 0.04 ENSG00000238295
.
7257
0.15
chr13_24827167_24827318 0.04 SPATA13-AS1
SPATA13 antisense RNA 1
1335
0.33
chr18_55448427_55448643 0.03 ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
21792
0.18
chr17_8867884_8868296 0.03 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
934
0.65
chr4_40203939_40204397 0.03 RHOH
ras homolog family member H
2204
0.34
chr5_133458466_133458617 0.03 TCF7
transcription factor 7 (T-cell specific, HMG-box)
768
0.69
chr3_32993605_32993756 0.03 CCR4
chemokine (C-C motif) receptor 4
614
0.81
chr18_22811215_22811414 0.03 ZNF521
zinc finger protein 521
180
0.97
chr17_54374886_54375091 0.03 ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
123452
0.06
chr7_50347932_50348149 0.03 IKZF1
IKAROS family zinc finger 1 (Ikaros)
277
0.95
chr1_76253803_76253986 0.03 ENSG00000207241
.
320
0.71
chr2_175358586_175358744 0.03 GPR155
G protein-coupled receptor 155
6843
0.2
chr14_106372328_106372479 0.03 ENSG00000211925
.
696
0.18
chr8_66748245_66748396 0.03 PDE7A
phosphodiesterase 7A
2663
0.39
chr22_41080945_41081220 0.03 MCHR1
melanin-concentrating hormone receptor 1
5805
0.23
chr4_84099158_84099309 0.03 PLAC8
placenta-specific 8
41005
0.17
chr15_40599321_40599893 0.03 PLCB2
phospholipase C, beta 2
419
0.68
chr6_31696965_31697269 0.02 DDAH2
dimethylarginine dimethylaminohydrolase 2
161
0.79
chr1_208056644_208056795 0.02 CD34
CD34 molecule
7118
0.29
chr5_79603471_79603622 0.02 ENSG00000251828
.
1359
0.41
chr10_51624082_51624233 0.02 TIMM23
translocase of inner mitochondrial membrane 23 homolog (yeast)
819
0.62
chr3_152001271_152001556 0.02 MBNL1-AS1
MBNL1 antisense RNA 1
14069
0.21
chr17_62961816_62962168 0.02 AMZ2P1
archaelysin family metallopeptidase 2 pseudogene 1
7643
0.15
chr4_90031662_90031813 0.02 TIGD2
tigger transposable element derived 2
2231
0.34
chr6_10528716_10529334 0.02 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
436
0.83
chr12_116982362_116982513 0.02 MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
14749
0.27
chr20_8113545_8114201 0.02 PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
571
0.84
chr21_16726840_16726991 0.02 ENSG00000212564
.
259687
0.02
chr9_88555446_88555764 0.02 NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
456
0.9
chr12_122327188_122327341 0.02 PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
572
0.69
chr20_47808077_47808228 0.02 STAU1
staufen double-stranded RNA binding protein 1
3248
0.24
chr18_11851450_11852068 0.02 CHMP1B
charged multivesicular body protein 1B
364
0.71
chr19_10346719_10347362 0.02 DNMT1
DNA (cytosine-5-)-methyltransferase 1
5078
0.09
chr19_37862447_37862678 0.02 ZNF527
zinc finger protein 527
466
0.79
chr17_43025339_43025574 0.02 KIF18B
kinesin family member 18B
374
0.78
chr7_128002255_128002406 0.02 PRRT4
proline-rich transmembrane protein 4
591
0.68
chr14_100535763_100535976 0.02 EVL
Enah/Vasp-like
3095
0.2
chr7_87506467_87506705 0.02 SLC25A40
solute carrier family 25, member 40
922
0.44
chr5_130881277_130881428 0.02 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
12626
0.29
chr2_191746520_191746971 0.02 AC005540.3

40
0.96
chr15_49102374_49102526 0.02 CEP152
centrosomal protein 152kDa
341
0.57
chr7_8011540_8011691 0.02 AC006042.7

2081
0.27
chr17_75437754_75438017 0.02 ENSG00000200651
.
306
0.87
chr7_98477525_98477676 0.02 TRRAP
transformation/transcription domain-associated protein
1113
0.38
chr19_18770811_18771071 0.02 KLHL26
kelch-like family member 26
23074
0.1
chr5_72111691_72111929 0.02 TNPO1
transportin 1
329
0.68
chr2_124669854_124670005 0.02 ENSG00000223118
.
42782
0.2
chr10_111770016_111770167 0.02 ADD3
adducin 3 (gamma)
2369
0.3
chr17_40424757_40425084 0.02 AC003104.1

219
0.88
chr1_99336669_99336925 0.02 RP5-896L10.1

133035
0.05
chr7_142013111_142013262 0.02 PRSS3P3
protease, serine, 3 pseudogene 3
23577
0.2
chr14_100260916_100261174 0.02 EML1
echinoderm microtubule associated protein like 1
1273
0.55
chr1_226067206_226067421 0.02 TMEM63A
transmembrane protein 63A
1934
0.23
chr11_111895361_111896109 0.02 DLAT
dihydrolipoamide S-acetyltransferase
197
0.9
chr11_47572722_47572873 0.02 CELF1
CUGBP, Elav-like family member 1
1872
0.17
chr19_36395044_36395195 0.02 HCST
hematopoietic cell signal transducer
1679
0.17
chr11_2467288_2467521 0.02 KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
1183
0.4
chr19_13319766_13319917 0.02 CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
48373
0.08
chr2_70321192_70321429 0.02 PCBP1-AS1
PCBP1 antisense RNA 1
5332
0.17
chrX_47491637_47491788 0.02 CFP
complement factor properdin
2008
0.21
chr6_90120799_90121205 0.02 RRAGD
Ras-related GTP binding D
787
0.65
chr16_77755925_77756166 0.02 NUDT7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
366
0.87
chr1_235530756_235531012 0.02 TBCE
tubulin folding cofactor E
139
0.96
chr17_80858518_80858669 0.02 TBCD
tubulin folding cofactor D
175
0.95
chr10_73533824_73534035 0.02 C10orf54
chromosome 10 open reading frame 54
674
0.7
chr10_75818028_75818179 0.02 VCL
vinculin
25131
0.17
chr19_2269030_2269201 0.02 OAZ1
ornithine decarboxylase antizyme 1
370
0.56
chr7_132766918_132767069 0.02 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
151
0.87
chr1_29255082_29255406 0.02 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
14153
0.18
chr3_123753408_123753559 0.02 ENSG00000238512
.
27448
0.16
chr16_50315325_50315505 0.02 ADCY7
adenylate cyclase 7
1977
0.34
chr19_17357282_17357631 0.02 NR2F6
nuclear receptor subfamily 2, group F, member 6
707
0.42
chr15_69110393_69110544 0.02 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
2757
0.31
chr9_139929883_139930034 0.02 FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
2496
0.09
chr11_62493191_62493431 0.02 HNRNPUL2
heterogeneous nuclear ribonucleoprotein U-like 2
1510
0.15
chr3_13056686_13056902 0.02 IQSEC1
IQ motif and Sec7 domain 1
28258
0.23
chr12_63253018_63253169 0.02 ENSG00000200296
.
8412
0.26
chr19_45620700_45620939 0.02 AC005757.6

19416
0.08
chr17_38947662_38947813 0.02 KRT28
keratin 28
8474
0.1
chr7_130790301_130790526 0.02 LINC-PINT
long intergenic non-protein coding RNA, p53 induced transcript
1376
0.46
chr5_39195697_39195848 0.02 FYB
FYN binding protein
7357
0.29
chr15_50410621_50410772 0.02 ATP8B4
ATPase, class I, type 8B, member 4
723
0.73
chr19_11457236_11457593 0.02 CCDC159
coiled-coil domain containing 159
182
0.46
chr1_98385360_98386215 0.02 DPYD
dihydropyrimidine dehydrogenase
766
0.78
chr17_2689592_2689743 0.02 RAP1GAP2
RAP1 GTPase activating protein 2
9317
0.16
chr1_108464074_108464225 0.02 VAV3-AS1
VAV3 antisense RNA 1
42916
0.16
chr21_37693064_37693535 0.02 AP000692.10

331
0.74
chr5_149789702_149789913 0.02 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
2488
0.26
chr17_66255315_66255711 0.02 ARSG
arylsulfatase G
190
0.93
chr11_95418104_95418255 0.02 FAM76B
family with sequence similarity 76, member B
101790
0.07
chr9_132000020_132000171 0.02 ENSG00000220992
.
7099
0.18
chr19_44488599_44488754 0.02 ZNF155
zinc finger protein 155
303
0.82
chr12_122517366_122517604 0.02 MLXIP
MLX interacting protein
857
0.66
chr16_85768387_85768538 0.02 ENSG00000222190
.
6844
0.12
chr5_52096731_52097099 0.02 CTD-2288O8.1

13055
0.19
chr16_48655716_48655879 0.02 N4BP1
NEDD4 binding protein 1
11677
0.18
chr1_24239672_24239931 0.02 CNR2
cannabinoid receptor 2 (macrophage)
51
0.95
chr22_24537742_24537893 0.02 CABIN1
calcineurin binding protein 1
13989
0.16
chr5_175963281_175963585 0.02 RNF44
ring finger protein 44
988
0.42
chr17_7154023_7154644 0.02 CTDNEP1
CTD nuclear envelope phosphatase 1
272
0.53
chr22_29194035_29194328 0.02 XBP1
X-box binding protein 1
1940
0.23
chr13_45910861_45911012 0.02 ENSG00000253051
.
354
0.67
chr8_95972695_95972978 0.02 NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
2600
0.21
chr5_102596450_102596781 0.02 C5orf30
chromosome 5 open reading frame 30
1490
0.46
chr14_24607151_24607302 0.02 PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
1790
0.12
chr9_69262672_69262918 0.02 CBWD6
COBW domain containing 6
202
0.94
chr2_198173822_198174153 0.02 ANKRD44
ankyrin repeat domain 44
1524
0.32
chr17_9478666_9479117 0.02 STX8
syntaxin 8
263
0.83
chr7_6629930_6630111 0.02 C7orf26
chromosome 7 open reading frame 26
245
0.85
chr10_14643816_14644958 0.02 FAM107B
family with sequence similarity 107, member B
2001
0.38
chr12_102018711_102018862 0.02 RP11-755O11.2

25940
0.14
chr13_78270363_78270592 0.02 SLAIN1
SLAIN motif family, member 1
1546
0.35
chr5_72144723_72145705 0.02 TNPO1
transportin 1
1203
0.49
chr3_44802588_44803091 0.02 KIAA1143
KIAA1143
315
0.52
chr2_64072820_64072971 0.02 UGP2
UDP-glucose pyrophosphorylase 2
313
0.93
chr16_56775385_56775536 0.02 NUP93
nucleoporin 93kDa
834
0.5
chr11_64108374_64108555 0.02 CCDC88B
coiled-coil domain containing 88B
769
0.4
chr12_51762995_51763159 0.02 GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
14270
0.14
chr22_37680309_37680627 0.02 CYTH4
cytohesin 4
1940
0.3
chrX_19362865_19363070 0.02 PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
881
0.68
chr20_56008241_56008392 0.02 RP4-800J21.3

40198
0.12
chr1_229478945_229479176 0.02 CCSAP
centriole, cilia and spindle-associated protein
325
0.86
chr9_70856505_70856767 0.02 CBWD3
COBW domain containing 3
239
0.92
chr9_179160_179373 0.02 CBWD1
COBW domain containing 1
194
0.94
chr11_84633973_84634163 0.02 DLG2
discs, large homolog 2 (Drosophila)
156
0.97
chr14_93133172_93133323 0.01 RIN3
Ras and Rab interactor 3
14401
0.25
chr3_107820035_107820186 0.01 CD47
CD47 molecule
10238
0.3
chr11_66138627_66138850 0.01 SLC29A2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
553
0.52
chr17_38459758_38459909 0.01 RARA
retinoic acid receptor, alpha
5611
0.13
chrX_73070691_73070842 0.01 RP13-216E22.5

118554
0.06
chr12_9144585_9144883 0.01 KLRG1
killer cell lectin-like receptor subfamily G, member 1
68
0.97
chr1_227070661_227070872 0.01 PSEN2
presenilin 2 (Alzheimer disease 4)
1558
0.44
chr10_51370591_51371314 0.01 AGAP8
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
369
0.53
chr2_114195012_114195248 0.01 CBWD2
COBW domain containing 2
138
0.95
chr8_33342029_33342180 0.01 MAK16
MAK16 homolog (S. cerevisiae)
164
0.94
chr9_139737618_139737804 0.01 C9orf172
chromosome 9 open reading frame 172
1156
0.22
chr19_18429580_18429756 0.01 LSM4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
2599
0.15
chr2_171555186_171555337 0.01 AC007277.3

3377
0.22
chr7_6673989_6674140 0.01 ZNF853
zinc finger protein 853
18816
0.11
chr8_9008533_9008971 0.01 PPP1R3B
protein phosphatase 1, regulatory subunit 3B
332
0.62
chr20_54989282_54989551 0.01 CASS4
Cas scaffolding protein family member 4
2099
0.24
chr8_30556332_30556483 0.01 GSR
glutathione reductase
28120
0.16
chr13_52397484_52397635 0.01 RP11-327P2.5

19126
0.17
chrX_102001474_102001892 0.01 BHLHB9
basic helix-loop-helix domain containing, class B, 9
661
0.72
chr9_70490242_70490494 0.01 CBWD5
COBW domain containing 5
122
0.98
chr1_1136100_1136251 0.01 TNFRSF18
tumor necrosis factor receptor superfamily, member 18
4885
0.08
chr10_90750353_90750504 0.01 FAS
Fas cell surface death receptor
14
0.92
chr20_46364288_46364439 0.01 SULF2
sulfatase 2
49870
0.14
chr14_91865794_91865945 0.01 CCDC88C
coiled-coil domain containing 88C
17821
0.22
chr6_36880305_36880530 0.01 C6orf89
chromosome 6 open reading frame 89
26777
0.14
chr14_105885619_105886050 0.01 RP11-521B24.3

242
0.57
chr14_91866311_91866542 0.01 CCDC88C
coiled-coil domain containing 88C
17264
0.22
chr20_62535394_62535545 0.01 ENSG00000199805
.
4839
0.08
chr17_78821534_78821685 0.01 RP11-28G8.1

42177
0.14
chr7_155131352_155131503 0.01 BLACE
B-cell acute lymphoblastic leukemia expressed
29202
0.15
chr6_35014998_35015149 0.01 TCP11
t-complex 11, testis-specific
73749
0.09
chr7_44645646_44645804 0.01 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
446
0.81
chr5_16465054_16465892 0.01 ZNF622
zinc finger protein 622
428
0.86
chr11_31391385_31392006 0.01 DNAJC24
DnaJ (Hsp40) homolog, subfamily C, member 24
291
0.57
chr21_36715747_36715917 0.01 RUNX1
runt-related transcription factor 1
294191
0.01
chr13_22245209_22245388 0.01 FGF9
fibroblast growth factor 9
224
0.95
chr19_50003533_50003936 0.01 hsa-mir-150
hsa-mir-150
47
0.8
chr16_67513595_67513746 0.01 ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
1312
0.23
chr9_36193726_36193938 0.01 CLTA
clathrin, light chain A
2872
0.25
chr16_71843274_71843511 0.01 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
288
0.87
chr4_56812643_56812942 0.01 CEP135
centrosomal protein 135kDa
2245
0.32
chr11_123374923_123375196 0.01 GRAMD1B
GRAM domain containing 1B
21285
0.22
chr2_71701457_71701608 0.01 DYSF
dysferlin
7700
0.27
chr11_2466894_2467127 0.01 KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
789
0.56
chr15_83419318_83419891 0.01 RP11-752G15.6

268
0.86
chr1_28196256_28196434 0.01 THEMIS2
thymocyte selection associated family member 2
2710
0.16
chr1_208041809_208042068 0.01 CD34
CD34 molecule
21899
0.23
chr7_127667736_127667887 0.01 LRRC4
leucine rich repeat containing 4
3247
0.32
chr11_31831358_31831638 0.01 PAX6
paired box 6
355
0.87
chr16_70467072_70467318 0.01 ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
5796
0.13
chr22_17567534_17567787 0.01 IL17RA
interleukin 17 receptor A
1811
0.31
chr19_42721386_42721863 0.01 DEDD2
death effector domain containing 2
197
0.87
chr14_22998901_22999052 0.01 TRAJ15
T cell receptor alpha joining 15
396
0.76
chr17_43664021_43664172 0.01 RP11-798G7.4

27660
0.11
chr9_92015629_92015819 0.01 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
5117
0.27
chr16_83761086_83761237 0.01 RP11-298D21.2

1179
0.45
chr1_154317465_154317703 0.01 ENSG00000238365
.
6365
0.11
chr1_172106062_172106431 0.01 ENSG00000207949
.
1801
0.34
chr1_32715929_32716174 0.01 LCK
lymphocyte-specific protein tyrosine kinase
789
0.4
chr8_19553922_19554073 0.01 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
13725
0.29
chr9_115248402_115248939 0.01 KIAA1958
KIAA1958
457
0.66
chr3_93781843_93782253 0.01 DHFRL1
dihydrofolate reductase-like 1
19
0.8
chr5_130598985_130599244 0.01 CDC42SE2
CDC42 small effector 2
588
0.84
chr7_158496384_158496597 0.01 NCAPG2
non-SMC condensin II complex, subunit G2
967
0.62
chr17_61629421_61629699 0.01 DCAF7
DDB1 and CUL4 associated factor 7
1699
0.27
chr11_71791059_71791281 0.01 LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
212
0.52
chr14_22959148_22959353 0.01 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
3079
0.14
chr11_11642887_11643184 0.01 GALNT18
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18
517
0.82
chr9_127976807_127976958 0.01 RABEPK
Rab9 effector protein with kelch motifs
13998
0.14
chr18_48405507_48405704 0.01 ME2
malic enzyme 2, NAD(+)-dependent, mitochondrial
115
0.97
chr16_27241764_27241915 0.01 NSMCE1
non-SMC element 1 homolog (S. cerevisiae)
2560
0.25
chr2_121268328_121268479 0.01 LINC01101
long intergenic non-protein coding RNA 1101
44706
0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of FIGLA

PNG image of the network

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Gene Ontology Analysis