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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for FLI1

Z-value: 1.57

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Transcription factors associated with FLI1

Gene Symbol	Gene ID	Gene Info
FLI1 Ensembl NCBI GeneCards UniProt	ENSG00000151702.12	Fli-1 proto-oncogene, ETS transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_128660057_128660214	FLI1	25450	0.181398	-0.81	7.9e-03	Click!
chr11_128636422_128636573	FLI1	1812	0.401136	-0.80	9.7e-03	Click!
chr11_128646889_128647040	FLI1	12279	0.216354	-0.72	2.7e-02	Click!
chr11_128559988_128560195	FLI1	2298	0.263741	-0.68	4.3e-02	Click!
chr11_128560277_128560436	FLI1	2033	0.289453	-0.64	6.1e-02	Click!

Activity of the FLI1 motif across conditions

Conditions sorted by the z-value of the FLI1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_161038546_161039545	1.04	ARHGAP30	Rho GTPase activating protein 30	411	0.65
chr2_61095077_61095367	0.85	REL	v-rel avian reticuloendotheliosis viral oncogene homolog	13434	0.18
chr3_177256670_177257021	0.80	ENSG00000252028	.	35505	0.22
chr22_33040519_33040909	0.77	ENSG00000251890	.	9530	0.25
chr18_13464907_13465379	0.77	LDLRAD4	low density lipoprotein receptor class A domain containing 4	129	0.93
chr11_6767215_6767876	0.76	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2	22741	0.11
chr14_88471433_88472132	0.73	GPR65	G protein-coupled receptor 65	314	0.88
chr17_4389769_4390006	0.70	RP13-580F15.2		239	0.89
chr17_7239932_7240900	0.69	ACAP1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	507	0.51
chr2_231508439_231508868	0.69	ENSG00000199791	.	56817	0.11
chr1_150082423_150082787	0.68	PLEKHO1	pleckstrin homology domain containing, family O member 1	38768	0.11
chr12_58135257_58135844	0.67	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	390	0.63
chr12_9912315_9912520	0.66	CD69	CD69 molecule	1080	0.47
chr10_43947307_43947516	0.66	ENSG00000252532	.	6102	0.17
chr2_242556723_242557374	0.64	THAP4	THAP domain containing 4	132	0.94
chr6_35279100_35279566	0.64	DEF6	differentially expressed in FDCP 6 homolog (mouse)	1818	0.34
chr2_182324285_182324673	0.64	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	2324	0.44
chr13_75900993_75901212	0.63	TBC1D4	TBC1 domain family, member 4	14565	0.24
chr3_3214996_3215328	0.63	CRBN	cereblon	6196	0.2
chr1_64709067_64709297	0.62	UBE2U	ubiquitin-conjugating enzyme E2U (putative)	22635	0.23
chr5_130882612_130883040	0.62	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	14100	0.29
chr17_75662930_75663081	0.61	SEPT9	septin 9	185010	0.03
chr19_3179462_3180177	0.60	S1PR4	sphingosine-1-phosphate receptor 4	1083	0.38
chr14_105527834_105528220	0.60	GPR132	G protein-coupled receptor 132	3740	0.23
chr10_134260489_134261029	0.60	C10orf91	chromosome 10 open reading frame 91	2066	0.3
chr10_28622520_28622887	0.60	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	712	0.72
chr2_68592484_68592752	0.56	AC015969.3		98	0.77
chr20_58630648_58631293	0.56	C20orf197	chromosome 20 open reading frame 197	10	0.98
chr11_67176589_67176876	0.55	TBC1D10C	TBC1 domain family, member 10C	5072	0.07
chr1_239883177_239883989	0.55	CHRM3	cholinergic receptor, muscarinic 3	740	0.59
chr15_75160410_75160789	0.55	SCAMP2	secretory carrier membrane protein 2	4782	0.12
chr12_53024457_53024608	0.55	KRT73	keratin 73	12189	0.1
chr10_94590680_94591107	0.54	EXOC6	exocyst complex component 6	42	0.99
chr14_100532787_100533367	0.54	EVL	Enah/Vasp-like	303	0.88
chr4_40199803_40200006	0.54	RHOH	ras homolog family member H	1377	0.47
chr11_64509794_64509966	0.54	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	529	0.68
chr3_121379230_121379471	0.53	HCLS1	hematopoietic cell-specific Lyn substrate 1	395	0.81
chr16_80598262_80598561	0.53	RP11-525K10.3		1379	0.4
chr1_209929583_209930044	0.53	TRAF3IP3	TRAF3 interacting protein 3	289	0.87
chr2_98334930_98335281	0.52	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	5082	0.19
chr2_191929470_191929872	0.52	ENSG00000231858	.	43419	0.12
chr10_111817998_111818272	0.52	ADD3	adducin 3 (gamma)	50413	0.13
chr19_3136242_3137376	0.51	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	618	0.58
chr5_61874491_61874642	0.50	LRRC70	leucine rich repeat containing 70	4	0.56
chr19_6481304_6482171	0.50	DENND1C	DENN/MADD domain containing 1C	27	0.95
chr1_198609761_198609912	0.49	PTPRC	protein tyrosine phosphatase, receptor type, C	1544	0.48
chr1_198504017_198504170	0.49	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	5711	0.32
chr20_35258352_35258894	0.49	SLA2	Src-like-adaptor 2	15661	0.12
chr7_150329208_150329551	0.49	GIMAP6	GTPase, IMAP family member 6	55	0.98
chr2_113933295_113933446	0.49	AC016683.5		433	0.74
chr1_25254983_25255134	0.49	RUNX3	runt-related transcription factor 3	554	0.81
chr4_40208145_40208346	0.49	RHOH	ras homolog family member H	6281	0.23
chr11_10645165_10645316	0.49	MRVI1	murine retrovirus integration site 1 homolog	28492	0.14
chr9_134150453_134150757	0.49	FAM78A	family with sequence similarity 78, member A	1329	0.42
chr7_150148744_150149359	0.49	GIMAP8	GTPase, IMAP family member 8	1333	0.41
chr1_160676943_160677601	0.48	CD48	CD48 molecule	4321	0.18
chr7_45017629_45017804	0.48	MYO1G	myosin IG	981	0.45
chr7_38398847_38399253	0.47	AMPH	amphiphysin	103663	0.08
chr7_137619960_137620169	0.47	CREB3L2	cAMP responsive element binding protein 3-like 2	1428	0.46
chr22_40298890_40299260	0.47	GRAP2	GRB2-related adaptor protein 2	1962	0.3
chr2_158296564_158297076	0.46	CYTIP	cytohesin 1 interacting protein	894	0.5
chr1_12405311_12405726	0.46	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	64406	0.11
chr1_6086479_6086932	0.45	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	325	0.88
chr2_175498105_175498391	0.45	WIPF1	WAS/WASL interacting protein family, member 1	1059	0.58
chr1_117297598_117297897	0.45	CD2	CD2 molecule	658	0.75
chr17_265803_266293	0.45	AC108004.3		2234	0.23
chr17_4336857_4337447	0.45	SPNS3	spinster homolog 3 (Drosophila)	67	0.97
chr12_96605794_96606075	0.45	RP11-394J1.2		11817	0.2
chr5_156608214_156608444	0.45	ITK	IL2-inducible T-cell kinase	492	0.72
chr11_1874347_1875032	0.44	LSP1	lymphocyte-specific protein 1	489	0.65
chr5_130617597_130618118	0.44	CDC42SE2	CDC42 small effector 2	18064	0.27
chr19_15574418_15574723	0.44	RASAL3	RAS protein activator like 3	812	0.5
chrX_78417700_78417909	0.44	GPR174	G protein-coupled receptor 174	8665	0.33
chr13_114905676_114905991	0.44	RASA3	RAS p21 protein activator 3	7747	0.23
chr14_22538566_22539116	0.44	ENSG00000238634	.	72046	0.12
chrX_4158791_4158942	0.44	ENSG00000264861	.	342675	0.01
chr3_56789114_56789483	0.44	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	20297	0.25
chr3_111261912_111262220	0.44	CD96	CD96 molecule	1069	0.62
chr3_112215334_112215665	0.44	BTLA	B and T lymphocyte associated	2706	0.33
chr1_111416320_111416529	0.43	CD53	CD53 molecule	648	0.73
chr19_10449910_10450285	0.43	ICAM3	intercellular adhesion molecule 3	198	0.86
chr12_10220623_10220774	0.43	ENSG00000223042	.	16087	0.12
chr19_6773526_6773780	0.43	VAV1	vav 1 guanine nucleotide exchange factor	684	0.58
chr12_117535875_117536067	0.43	TESC	tescalcin	1280	0.57
chr20_25017046_25017337	0.43	ACSS1	acyl-CoA synthetase short-chain family member 1	3852	0.24
chr9_130665887_130666038	0.43	ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	1647	0.19
chr22_17700031_17700512	0.43	CECR1	cat eye syndrome chromosome region, candidate 1	5	0.98
chr6_225379_225671	0.43	DUSP22	dual specificity phosphatase 22	66105	0.15
chr5_74964815_74965486	0.42	ENSG00000207333	.	40274	0.14
chr16_50780900_50781420	0.42	CYLD	cylindromatosis (turban tumor syndrome)	2300	0.18
chr11_63974616_63975431	0.42	FERMT3	fermitin family member 3	266	0.78
chr14_24906611_24906867	0.42	SDR39U1	short chain dehydrogenase/reductase family 39U, member 1	3518	0.13
chr14_22952184_22952433	0.42	ENSG00000251002	.	360	0.73
chr12_104871725_104872091	0.42	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	21129	0.25
chr5_171610848_171611129	0.42	STK10	serine/threonine kinase 10	4402	0.22
chr12_47609896_47610314	0.41	PCED1B	PC-esterase domain containing 1B	53	0.98
chr6_170404507_170404739	0.41	RP11-302L19.1		73118	0.11
chr11_68099084_68099235	0.41	LRP5	low density lipoprotein receptor-related protein 5	19082	0.2
chr4_84035760_84036001	0.41	PLAC8	placenta-specific 8	9	0.98
chr9_95726568_95726886	0.41	FGD3	FYVE, RhoGEF and PH domain containing 3	484	0.84
chr15_75069590_75069869	0.41	CSK	c-src tyrosine kinase	4669	0.13
chr1_204482334_204482501	0.41	MDM4	Mdm4 p53 binding protein homolog (mouse)	3094	0.23
chr1_234980313_234980644	0.41	ENSG00000201638	.	6758	0.28
chr1_27757398_27757629	0.41	GPR3	G protein-coupled receptor 3	38365	0.1
chr7_37486894_37487045	0.41	ELMO1	engulfment and cell motility 1	1584	0.4
chr17_81026922_81027073	0.40	METRNL	meteorin, glial cell differentiation regulator-like	10570	0.21
chr12_47609308_47609580	0.40	PCED1B	PC-esterase domain containing 1B	608	0.77
chr6_36975031_36975182	0.40	FGD2	FYVE, RhoGEF and PH domain containing 2	1683	0.34
chr1_26646074_26646278	0.40	UBXN11	UBX domain protein 11	1322	0.27
chr3_183273606_183273960	0.40	KLHL6	kelch-like family member 6	306	0.89
chr13_30947629_30947892	0.40	KATNAL1	katanin p60 subunit A-like 1	66139	0.12
chr2_97627619_97627770	0.40	ENSG00000252845	.	5142	0.16
chr1_9777067_9777879	0.40	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	654	0.69
chr12_7062613_7062865	0.40	PTPN6	protein tyrosine phosphatase, non-receptor type 6	2201	0.1
chr7_150382525_150383418	0.40	GIMAP2	GTPase, IMAP family member 2	156	0.95
chr1_206732541_206732911	0.40	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	2233	0.27
chr9_92034055_92034354	0.40	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	456	0.87
chr8_141608249_141608648	0.40	AGO2	argonaute RISC catalytic component 2	7539	0.25
chr2_8628153_8628374	0.39	AC011747.7		187633	0.03
chr19_48774376_48774742	0.39	ZNF114	zinc finger protein 114	70	0.95
chr14_91882732_91883366	0.39	CCDC88C	coiled-coil domain containing 88C	641	0.78
chr16_50308842_50309053	0.39	ADCY7	adenylate cyclase 7	883	0.62
chr7_38389675_38390189	0.39	AMPH	amphiphysin	112781	0.07
chr22_30698293_30698529	0.39	RP1-130H16.18	Uncharacterized protein	2940	0.13
chrX_12969173_12969416	0.39	TMSB4X	thymosin beta 4, X-linked	23933	0.18
chr11_64107746_64107914	0.39	CCDC88B	coiled-coil domain containing 88B	135	0.9
chr1_112016807_112017159	0.39	C1orf162	chromosome 1 open reading frame 162	492	0.65
chr16_67679075_67679512	0.39	RLTPR	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	143	0.91
chrX_56791675_56792116	0.39	ENSG00000204272	.	36203	0.23
chr11_122545918_122546069	0.39	UBASH3B	ubiquitin associated and SH3 domain containing B	19610	0.22
chr6_41168130_41168571	0.39	TREML2	triggering receptor expressed on myeloid cells-like 2	582	0.65
chr11_46367528_46367907	0.39	DGKZ	diacylglycerol kinase, zeta	730	0.6
chr19_2281331_2281581	0.39	C19orf35	chromosome 19 open reading frame 35	719	0.44
chr11_104941043_104941194	0.39	CARD16	caspase recruitment domain family, member 16	25015	0.15
chr9_134148873_134149024	0.39	FAM78A	family with sequence similarity 78, member A	2986	0.24
chr1_93802327_93802478	0.39	ENSG00000223745	.	547	0.77
chr1_36042987_36043882	0.38	RP4-728D4.2		104	0.95
chr3_112217855_112218341	0.38	BTLA	B and T lymphocyte associated	107	0.98
chr10_125799168_125799413	0.38	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	6951	0.29
chr9_137288293_137289070	0.38	RXRA	retinoid X receptor, alpha	9747	0.23
chr4_74960008_74960159	0.38	CXCL2	chemokine (C-X-C motif) ligand 2	4927	0.18
chr21_43483571_43483940	0.38	UMODL1	uromodulin-like 1	687	0.71
chr19_13206703_13207270	0.38	LYL1	lymphoblastic leukemia derived sequence 1	6695	0.11
chr4_40207085_40207549	0.38	RHOH	ras homolog family member H	5353	0.24
chr1_207094320_207094619	0.38	FAIM3	Fas apoptotic inhibitory molecule 3	743	0.59
chr7_106507255_106507406	0.38	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	1406	0.54
chr21_36419137_36419702	0.38	RUNX1	runt-related transcription factor 1	2043	0.49
chr2_198064152_198064348	0.38	ANKRD44	ankyrin repeat domain 44	1488	0.35
chr22_44578201_44578448	0.38	PARVG	parvin, gamma	583	0.83
chr17_27220072_27220391	0.38	RP11-20B24.7		744	0.4
chr2_430021_430194	0.38	FAM150B	family with sequence similarity 150, member B	141256	0.04
chr1_40524970_40525405	0.38	CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	18633	0.16
chr5_171542788_171542949	0.38	ENSG00000266671	.	34888	0.16
chr13_46752366_46752713	0.37	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	3920	0.19
chrX_118815979_118816490	0.37	SEPT6	septin 6	10558	0.17
chr2_106776864_106777181	0.37	UXS1	UDP-glucuronate decarboxylase 1	18	0.98
chr2_136873275_136873680	0.37	CXCR4	chemokine (C-X-C motif) receptor 4	336	0.93
chr8_21769513_21769765	0.37	DOK2	docking protein 2, 56kDa	1535	0.4
chr13_100072035_100072186	0.37	ENSG00000266207	.	33613	0.16
chrX_129225814_129226276	0.37	ELF4	E74-like factor 4 (ets domain transcription factor)	18291	0.19
chr10_129861236_129861473	0.37	PTPRE	protein tyrosine phosphatase, receptor type, E	15520	0.26
chr17_17660862_17661247	0.37	RAI1-AS1	RAI1 antisense RNA 1	13081	0.13
chr1_111415148_111415389	0.37	CD53	CD53 molecule	507	0.81
chr12_65063390_65063633	0.37	RP11-338E21.3		14712	0.13
chr13_33607800_33607951	0.37	ENSG00000221677	.	7614	0.24
chr21_40138917_40139228	0.37	ETS2	v-ets avian erythroblastosis virus E26 oncogene homolog 2	38159	0.2
chr14_75714424_75714717	0.37	RP11-293M10.2		11544	0.15
chr7_37392669_37392863	0.37	ELMO1	engulfment and cell motility 1	506	0.77
chr13_91922419_91922570	0.37	ENSG00000215417	.	80365	0.12
chr12_118797370_118797521	0.37	TAOK3	TAO kinase 3	36	0.98
chr16_3626426_3626694	0.37	NLRC3	NLR family, CARD domain containing 3	832	0.54
chr1_89664664_89664873	0.37	GBP4	guanylate binding protein 4	153	0.96
chr19_48761528_48762054	0.37	CARD8	caspase recruitment domain family, member 8	2588	0.17
chr16_29676714_29676865	0.37	QPRT	quinolinate phosphoribosyltransferase	2189	0.2
chrX_70323668_70324217	0.37	CXorf65	chromosome X open reading frame 65	2513	0.16
chr17_27912208_27912435	0.36	GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	1431	0.21
chr2_120687234_120687484	0.36	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	7	0.98
chr7_105318637_105318983	0.36	ATXN7L1	ataxin 7-like 1	799	0.74
chr6_128272436_128272587	0.36	THEMIS	thymocyte selection associated	32735	0.2
chr9_3398052_3398553	0.36	RFX3	regulatory factor X, 3 (influences HLA class II expression)	2706	0.4
chr17_47765494_47765708	0.36	SPOP	speckle-type POZ protein	10005	0.14
chr9_139990412_139990681	0.36	ENSG00000199411	.	1749	0.12
chr2_192540821_192541028	0.36	NABP1	nucleic acid binding protein 1	1938	0.47
chr11_118178183_118178334	0.36	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	2644	0.19
chr9_126628860_126629011	0.36	DENND1A	DENN/MADD domain containing 1A	63451	0.12
chr9_127258219_127258370	0.36	NR5A1	nuclear receptor subfamily 5, group A, member 1	4971	0.23
chr17_19030873_19031152	0.36	GRAPL	GRB2-related adaptor protein-like	164	0.89
chr20_57237055_57237206	0.36	STX16	syntaxin 16	5446	0.18
chr4_148713676_148713874	0.36	ENSG00000264274	.	10029	0.19
chr22_37881004_37881696	0.36	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	683	0.62
chr3_140985922_140986285	0.36	ACPL2	acid phosphatase-like 2	4647	0.28
chr20_31127731_31127882	0.36	C20orf112	chromosome 20 open reading frame 112	3606	0.21
chr6_170580859_170581356	0.36	RP5-1086L22.1		9450	0.18
chr4_40198688_40199041	0.35	RHOH	ras homolog family member H	337	0.9
chr20_37503924_37504220	0.35	ENSG00000240474	.	2659	0.29
chr19_7415020_7415240	0.35	CTB-133G6.1		1282	0.4
chr5_544016_544540	0.35	ENSG00000264233	.	8281	0.14
chr12_54866933_54867431	0.35	GTSF1	gametocyte specific factor 1	201	0.92
chr7_36327271_36327770	0.35	EEPD1	endonuclease/exonuclease/phosphatase family domain containing 1	9233	0.18
chr17_38738771_38738954	0.35	CCR7	chemokine (C-C motif) receptor 7	17138	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FLI1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	0.7	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.2	0.9	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	0.7	GO:0010447	response to acidic pH(GO:0010447)
0.2	0.4	GO:0002913	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.2	0.6	GO:0033622	integrin activation(GO:0033622)
0.2	0.5	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.2	0.5	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.6	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.6	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	1.3	GO:0045061	thymic T cell selection(GO:0045061)
0.1	0.3	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.4	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1	0.5	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.3	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.3	GO:0015809	arginine transport(GO:0015809)
0.1	0.3	GO:0003323	type B pancreatic cell development(GO:0003323)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.3	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.3	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.2	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1	0.4	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.1	0.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.7	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.2	GO:0014805	smooth muscle adaptation(GO:0014805)
0.1	0.1	GO:0043383	negative T cell selection(GO:0043383)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.3	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.3	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.1	1.7	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1	0.3	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.1	0.3	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.1	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.1	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.9	GO:0016601	Rac protein signal transduction(GO:0016601)
0.1	0.1	GO:0006007	glucose catabolic process(GO:0006007)
0.1	0.2	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.1	GO:0002666	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.2	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.4	GO:0051642	centrosome localization(GO:0051642)
0.1	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.2	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1	0.4	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	0.3	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.3	GO:0001562	response to protozoan(GO:0001562)
0.1	0.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.2	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.9	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.1	GO:0060120	auditory receptor cell fate commitment(GO:0009912) auditory receptor cell fate determination(GO:0042668) inner ear receptor cell fate commitment(GO:0060120)
0.1	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.6	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.1	0.2	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	2.4	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.2	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.3	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0035304	regulation of protein dephosphorylation(GO:0035304)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.2	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0045359	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.1	GO:0002885	positive regulation of hypersensitivity(GO:0002885)
0.0	0.0	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.3	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.4	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.2	GO:0032747	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0051132	NK T cell activation(GO:0051132)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.6	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.5	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0060744	thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.3	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.1	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.2	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0010536	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.5	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0021554	optic nerve development(GO:0021554)
0.0	0.4	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0070293	renal absorption(GO:0070293)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.5	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.1	GO:0042992	negative regulation of transcription factor import into nucleus(GO:0042992)
0.0	0.2	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.3	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.1	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.0	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.2	GO:0048535	lymph node development(GO:0048535)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.7	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	1.4	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.6	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.7	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.2	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	1.2	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.3	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.4	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.9	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
0.0	0.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.2	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.2	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.2	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.2	GO:1903038	negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.0	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.0	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.2	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.0	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.3	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.0	GO:0045079	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.2	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.2	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.2	GO:0006595	polyamine metabolic process(GO:0006595)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.0	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.0	GO:0002532	production of molecular mediator involved in inflammatory response(GO:0002532)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691) negative regulation of interleukin-1 production(GO:0032692)
0.0	0.0	GO:0001783	B cell apoptotic process(GO:0001783)
0.0	0.1	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0048242	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.3	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.0	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.1	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0045010	actin nucleation(GO:0045010)
0.0	0.1	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.0	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.2	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.3	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.0	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.3	GO:0051017	actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.0	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.0	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.2	GO:0030316	osteoclast differentiation(GO:0030316)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:0010903	cytokine secretion involved in immune response(GO:0002374) regulation of cytokine secretion involved in immune response(GO:0002739) negative regulation of cytokine secretion involved in immune response(GO:0002740) negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0	0.7	GO:0042177	negative regulation of protein catabolic process(GO:0042177)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0046686	response to cadmium ion(GO:0046686)
0.0	0.0	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	2.5	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.2	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.0	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.0	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.2	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.0	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0046638	positive regulation of alpha-beta T cell differentiation(GO:0046638)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.1	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.0	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.0	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.0	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.3	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.2	GO:0006825	copper ion transport(GO:0006825)
0.0	0.2	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.0	GO:0048525	negative regulation of viral process(GO:0048525) negative regulation of viral life cycle(GO:1903901)
0.0	0.0	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0009268	response to pH(GO:0009268)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0075136	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0	0.0	GO:0032645	granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0061140	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510) lung secretory cell differentiation(GO:0061140)
0.0	0.1	GO:0070972	protein localization to endoplasmic reticulum(GO:0070972)
0.0	0.0	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.0	GO:0061082	myeloid leukocyte cytokine production(GO:0061082)
0.0	0.2	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.2	GO:0034341	response to interferon-gamma(GO:0034341)
0.0	0.0	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	1.0	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.5	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.5	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.5	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.2	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.5	GO:0000145	exocyst(GO:0000145)
0.1	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.4	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.6	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.4	GO:0042627	chylomicron(GO:0042627)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	1.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.6	GO:0032587	ruffle membrane(GO:0032587)
0.0	2.6	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.7	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	1.5	GO:0030027	lamellipodium(GO:0030027)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.4	GO:0005776	autophagosome(GO:0005776)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.0	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.6	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.1	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.4	GO:0005903	brush border(GO:0005903)
0.0	0.5	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.2	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.0	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0030130	trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.1	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0042608	T cell receptor binding(GO:0042608)
0.2	0.6	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.7	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	1.1	GO:0005522	profilin binding(GO:0005522)
0.1	0.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.7	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.5	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.3	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.3	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.4	GO:0070513	death domain binding(GO:0070513)
0.1	1.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.1	GO:0001846	opsonin binding(GO:0001846)
0.1	0.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1	0.2	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.2	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.1	0.2	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.4	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.8	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.3	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	1.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.8	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.5	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	1.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.5	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.4	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.2	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.5	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.7	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.7	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.6	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.3	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.9	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.0	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.2	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.3	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	1.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.5	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.6	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.4	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.0	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.0	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.4	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.3	GO:0043022	ribosome binding(GO:0043022)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0099528	dopamine neurotransmitter receptor activity(GO:0004952) G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.0	0.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.0	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.0	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.0	GO:0004559	alpha-mannosidase activity(GO:0004559)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.8	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.8	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	1.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	1.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	1.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.0	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.8	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	1.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.6	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.3	PID EPO PATHWAY	EPO signaling pathway
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.4	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.8	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.5	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.1	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.8	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.3	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.9	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.8	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	1.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	1.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.8	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	1.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	1.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	1.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.0	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.4	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.4	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	1.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.0	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME NEURONAL SYSTEM	Genes involved in Neuronal System
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism

Results for FLI1

Z-value: 1.57

Motif logo

Transcription factors associated with FLI1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the FLI1 motif across conditions

Conditions sorted by the z-value of the FLI1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FLI1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: