Project

ENCODE: H3K4me3 ChIP-Seq of primary human cells

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FOSL2_SMARCC1

Z-value: 1.04

Motif logo

Transcription factors associated with FOSL2_SMARCC1

Gene Symbol	Gene ID	Gene Info
FOSL2 Ensembl NCBI GeneCards UniProt	ENSG00000075426.7	FOSL2
SMARCC1 Ensembl NCBI GeneCards UniProt	ENSG00000173473.6	SMARCC1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
FOSL2	chr2_28589849_28590028	25731	0.150297	0.88	1.6e-03	Click!
FOSL2	chr2_28582365_28582516	33229	0.138157	0.87	2.5e-03	Click!
FOSL2	chr2_28601116_28601352	14435	0.165249	0.81	8.2e-03	Click!
FOSL2	chr2_28582657_28582808	32937	0.138655	0.79	1.1e-02	Click!
FOSL2	chr2_28600514_28600665	15080	0.164501	0.75	2.0e-02	Click!
SMARCC1	chr3_47822404_47822881	765	0.620272	0.60	8.5e-02	Click!
SMARCC1	chr3_47823051_47823226	269	0.903870	0.50	1.7e-01	Click!
SMARCC1	chr3_47831109_47831260	7777	0.168002	-0.34	3.7e-01	Click!
SMARCC1	chr3_47823573_47824113	436	0.811272	0.33	3.9e-01	Click!
SMARCC1	chr3_47822128_47822402	1142	0.460753	0.29	4.4e-01	Click!

Activity of the FOSL2_SMARCC1 motif across conditions

Conditions sorted by the z-value of the FOSL2_SMARCC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_150436563_150436714	0.48	TNIP1	TNFAIP3 interacting protein 1	8018	0.2
chr8_8945449_8945788	0.46	ENSG00000239078	.	15592	0.15
chr18_12005840_12005991	0.43	RP11-820I16.3		10978	0.16
chr19_4374737_4374888	0.42	SH3GL1	SH3-domain GRB2-like 1	5477	0.08
chr1_2266428_2266579	0.40	AL589739.1	Uncharacterized protein	7922	0.11
chr14_103801113_103802028	0.39	EIF5	eukaryotic translation initiation factor 5	284	0.87
chr3_27410282_27410923	0.37	NEK10	NIMA-related kinase 10	281	0.91
chr6_35453862_35454013	0.36	TEAD3	TEA domain family member 3	6038	0.17
chr10_121031057_121031208	0.36	ENSG00000242853	.	58763	0.09
chr2_202015949_202016344	0.36	CFLAR-AS1	CFLAR antisense RNA 1	263	0.88
chr17_73567230_73567381	0.36	MYO15B	myosin XVB pseudogene	19553	0.1
chr2_95940298_95940449	0.35	PROM2	prominin 2	128	0.97
chr19_2089959_2090185	0.35	MOB3A	MOB kinase activator 3A	103	0.94
chr7_100781654_100781965	0.35	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	11430	0.1
chr4_10182968_10183393	0.35	WDR1	WD repeat domain 1	64607	0.11
chr11_64099501_64099713	0.34	AP003774.1		2631	0.11
chr13_114830089_114831005	0.33	RASA3	RAS p21 protein activator 3	12891	0.24
chr7_36603678_36603829	0.33	AOAH	acyloxyacyl hydrolase (neutrophil)	30509	0.17
chr17_74495503_74495654	0.32	RHBDF2	rhomboid 5 homolog 2 (Drosophila)	1875	0.2
chr15_91459213_91459364	0.32	MAN2A2	mannosidase, alpha, class 2A, member 2	3170	0.11
chr6_35568962_35570321	0.32	ENSG00000212579	.	49954	0.1
chr16_31145770_31145921	0.31	PRSS8	protease, serine, 8	1116	0.22
chr2_231191950_231192650	0.31	SP140L	SP140 nuclear body protein-like	315	0.92
chr17_79798852_79799080	0.31	RP11-498C9.2		2075	0.12
chr1_30856346_30856497	0.30	MATN1-AS1	MATN1 antisense RNA 1	334930	0.01
chr10_45870440_45870591	0.30	ALOX5	arachidonate 5-lipoxygenase	840	0.69
chr1_198610920_198611071	0.30	PTPRC	protein tyrosine phosphatase, receptor type, C	2703	0.34
chr19_12897015_12897166	0.30	ENSG00000263800	.	852	0.31
chr2_147579520_147579813	0.30	ENSG00000238860	.	501873	0.0
chr17_4396255_4396406	0.30	SPNS2	spinster homolog 2 (Drosophila)	5803	0.13
chr11_11589938_11590089	0.29	RP11-483L5.1		1618	0.47
chr8_96237876_96238027	0.29	C8orf37	chromosome 8 open reading frame 37	43478	0.17
chr4_170001005_170001626	0.29	RP11-483A20.3		69734	0.1
chr12_109084399_109085395	0.29	CORO1C	coronin, actin binding protein, 1C	5281	0.17
chr1_151579139_151579290	0.29	SNX27	sorting nexin family member 27	5344	0.12
chr9_138022409_138022560	0.28	OLFM1	olfactomedin 1	34652	0.19
chr17_8976590_8976741	0.28	NTN1	netrin 1	51045	0.15
chr1_155102127_155102278	0.28	EFNA1	ephrin-A1	1850	0.14
chr17_2869143_2869294	0.28	CTD-3060P21.1		29	0.98
chr4_15907365_15907907	0.28	FGFBP1	fibroblast growth factor binding protein 1	32335	0.17
chr19_39894109_39894559	0.28	ZFP36	ZFP36 ring finger protein	3119	0.1
chr5_74964815_74965486	0.28	ENSG00000207333	.	40274	0.14
chr12_25207808_25208034	0.28	LRMP	lymphoid-restricted membrane protein	2247	0.32
chr20_61455814_61456027	0.27	COL9A3	collagen, type IX, alpha 3	6757	0.12
chr16_88366626_88367008	0.27	ZNF469	zinc finger protein 469	127062	0.05
chr2_99069202_99069353	0.27	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	7864	0.24
chrX_47489439_47489603	0.27	CFP	complement factor properdin	157	0.92
chr3_186993064_186993215	0.27	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	16346	0.21
chr11_104914891_104915295	0.26	CARD16	caspase recruitment domain family, member 16	941	0.54
chrX_38729814_38730081	0.26	MID1IP1-AS1	MID1IP1 antisense RNA 1	66811	0.12
chr4_79473579_79473973	0.26	ANXA3	annexin A3	655	0.79
chr19_48246517_48246668	0.26	GLTSCR2	glioma tumor suppressor candidate region gene 2	2187	0.21
chr20_52519916_52520067	0.26	AC005220.3		36708	0.2
chr8_10512332_10512483	0.26	RP1L1	retinitis pigmentosa 1-like 1	205	0.92
chr14_89345487_89345638	0.26	TTC8	tetratricopeptide repeat domain 8	37690	0.15
chr3_126206096_126206282	0.26	ZXDC	ZXD family zinc finger C	11427	0.16
chr11_11592510_11592661	0.26	RP11-483L5.1		954	0.65
chr17_80175660_80175811	0.26	RP13-516M14.2		3632	0.13
chrX_133147131_133147282	0.26	GPC3	glypican 3	27284	0.21
chr3_187491731_187491915	0.26	BCL6	B-cell CLL/lymphoma 6	28308	0.2
chr22_32058342_32058690	0.26	PISD	phosphatidylserine decarboxylase	98	0.97
chr16_31276706_31276857	0.26	ENSG00000252876	.	2031	0.19
chr1_25361354_25361505	0.26	ENSG00000264371	.	11435	0.23
chr1_244486436_244486726	0.25	C1orf100	chromosome 1 open reading frame 100	29356	0.21
chr9_132579196_132579347	0.25	TOR1A	torsin family 1, member A (torsin A)	7142	0.14
chr1_52159244_52159395	0.25	OSBPL9	oxysterol binding protein-like 9	24096	0.16
chr16_54459980_54460131	0.25	ENSG00000264079	.	123253	0.06
chr11_2395489_2395640	0.25	ENSG00000199550	.	1696	0.2
chr1_156630677_156631393	0.25	RP11-284F21.7		181	0.89
chr11_46378662_46378813	0.25	DGKZ	diacylglycerol kinase, zeta	4408	0.16
chr21_28802590_28802741	0.25	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	463833	0.01
chr11_129697989_129698558	0.25	TMEM45B	transmembrane protein 45B	12559	0.26
chr7_64407394_64407545	0.25	ZNF273	zinc finger protein 273	43835	0.11
chr1_248069833_248069987	0.25	OR2W3	olfactory receptor, family 2, subfamily W, member 3	11021	0.1
chr14_96312809_96312960	0.25	ENSG00000263357	.	5043	0.29
chr21_31012601_31012752	0.25	RP11-313P22.1		17050	0.22
chr17_6757690_6757943	0.24	TEKT1	tektin 1	22736	0.14
chrX_105065104_105065255	0.24	NRK	Nik related kinase	1357	0.55
chr1_41363272_41363423	0.24	RP5-1066H13.4		33761	0.14
chr2_109237700_109238010	0.24	LIMS1	LIM and senescent cell antigen-like domains 1	133	0.97
chr11_10695962_10696877	0.24	MRVI1	murine retrovirus integration site 1 homolog	18642	0.17
chr4_105982370_105982725	0.24	ENSG00000252136	.	44597	0.16
chr22_46409167_46409603	0.24	WNT7B	wingless-type MMTV integration site family, member 7B	36376	0.09
chr10_45872200_45872351	0.24	ALOX5	arachidonate 5-lipoxygenase	2600	0.34
chr15_89630929_89631312	0.24	RP11-326A19.3		52	0.77
chr4_27985809_27985960	0.24	RP11-180C1.1	Uncharacterized protein	418439	0.01
chr4_74922619_74922770	0.24	PPBPP2	pro-platelet basic protein pseudogene 2	2157	0.24
chr11_1884799_1884950	0.24	LSP1	lymphocyte-specific protein 1	398	0.51
chr14_75085047_75085411	0.24	LTBP2	latent transforming growth factor beta binding protein 2	5923	0.21
chr3_46989936_46990087	0.23	CCDC12	coiled-coil domain containing 12	28259	0.13
chr6_147197427_147197865	0.23	STXBP5-AS1	STXBP5 antisense RNA 1	25505	0.25
chr14_35871775_35873043	0.23	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	937	0.68
chr1_30602704_30603087	0.23	ENSG00000222787	.	245146	0.02
chr17_78865183_78865610	0.23	RPTOR	regulatory associated protein of MTOR, complex 1	31128	0.13
chr11_2198846_2198997	0.23	ENSG00000265258	.	4628	0.12
chr1_160983030_160983181	0.23	F11R	F11 receptor	7781	0.11
chr17_4762471_4762622	0.23	ENSG00000263599	.	16375	0.08
chr10_112086583_112086734	0.23	SMNDC1	survival motor neuron domain containing 1	21949	0.22
chr14_92997841_92998087	0.23	RIN3	Ras and Rab interactor 3	17816	0.26
chr19_48784148_48784299	0.23	ZNF114	zinc finger protein 114	9343	0.11
chr17_75439465_75439616	0.23	ENSG00000200651	.	1349	0.37
chr5_176874674_176875204	0.23	PRR7-AS1	PRR7 antisense RNA 1	239	0.62
chr12_111847113_111847630	0.23	SH2B3	SH2B adaptor protein 3	3619	0.23
chr2_219725294_219725445	0.23	WNT6	wingless-type MMTV integration site family, member 6	825	0.5
chr17_75138230_75138411	0.22	SEC14L1	SEC14-like 1 (S. cerevisiae)	852	0.63
chr1_235093242_235093393	0.22	ENSG00000239690	.	53384	0.15
chr17_39779992_39780143	0.22	KRT17	keratin 17	547	0.62
chr22_43288275_43288426	0.22	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	34238	0.17
chr2_25966238_25966389	0.22	ENSG00000222070	.	21252	0.18
chr3_93878024_93878443	0.22	ENSG00000253062	.	60823	0.12
chr3_64963602_64963753	0.22	ENSG00000264871	.	254981	0.02
chr10_45870253_45870404	0.22	ALOX5	arachidonate 5-lipoxygenase	653	0.77
chr17_55945610_55945963	0.22	CUEDC1	CUE domain containing 1	1010	0.52
chr3_53303838_53304218	0.22	ENSG00000238565	.	13291	0.12
chr9_111396808_111397109	0.22	ACTL7B	actin-like 7B	222281	0.02
chr20_1470626_1470777	0.22	SIRPB2	signal-regulatory protein beta 2	1341	0.29
chr10_54463336_54463751	0.22	RP11-556E13.1		51626	0.16
chr8_68515024_68515175	0.22	ENSG00000221660	.	108768	0.07
chr1_10961126_10961370	0.22	C1orf127	chromosome 1 open reading frame 127	46679	0.12
chr8_108509260_108510202	0.22	ANGPT1	angiopoietin 1	507	0.89
chr19_35951714_35951865	0.22	FFAR2	free fatty acid receptor 2	11172	0.11
chr6_35338140_35338402	0.22	PPARD	peroxisome proliferator-activated receptor delta	27869	0.16
chr2_111751565_111751824	0.22	ACOXL	acyl-CoA oxidase-like	6919	0.31
chr8_128310206_128310357	0.21	POU5F1B	POU class 5 homeobox 1B	116254	0.07
chr20_16800308_16800459	0.21	OTOR	otoraplin	71380	0.11
chr19_36248323_36248705	0.21	HSPB6	heat shock protein, alpha-crystallin-related, B6	466	0.38
chr3_31247061_31247212	0.21	ENSG00000222983	.	23071	0.23
chr7_20824481_20824853	0.21	SP8	Sp8 transcription factor	1838	0.51
chr8_11706405_11706556	0.21	RP11-589N15.2		2580	0.22
chr7_155090835_155091229	0.21	INSIG1	insulin induced gene 1	761	0.7
chr16_70780347_70780498	0.21	RP11-394B2.6		538	0.68
chr16_11753228_11753379	0.21	SNN	stannin	8967	0.18
chr12_121363997_121364148	0.21	SPPL3	signal peptide peptidase like 3	21898	0.14
chr3_5055062_5055354	0.21	BHLHE40-AS1	BHLHE40 antisense RNA 1	33562	0.15
chr7_1553073_1553492	0.21	AC102953.6		4219	0.16
chr6_133006336_133006628	0.21	VNN1	vanin 1	28706	0.12
chr13_34116508_34116659	0.21	STARD13	StAR-related lipid transfer (START) domain containing 13	191816	0.03
chr1_36808540_36808801	0.21	STK40	serine/threonine kinase 40	18271	0.12
chr9_130717791_130717942	0.21	FAM102A	family with sequence similarity 102, member A	4865	0.11
chr6_18488896_18489181	0.21	ENSG00000207775	.	82977	0.09
chr20_49983111_49983262	0.21	ENSG00000263645	.	10672	0.28
chr5_10632325_10632658	0.21	ANKRD33B-AS1	ANKRD33B antisense RNA 1	4154	0.28
chr2_206633742_206633893	0.21	AC007362.3		5087	0.3
chr13_50114703_50115207	0.21	RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	26504	0.17
chr14_50468177_50468632	0.21	C14orf182	chromosome 14 open reading frame 182	5834	0.2
chrX_19757821_19757972	0.21	SH3KBP1	SH3-domain kinase binding protein 1	1059	0.68
chr10_95143500_95143651	0.20	MYOF	myoferlin	98376	0.07
chr14_70120086_70120237	0.20	KIAA0247	KIAA0247	41848	0.16
chr2_134415347_134415498	0.20	ENSG00000200708	.	61760	0.14
chr2_8655367_8655518	0.20	AC011747.7		160454	0.04
chr15_89710840_89711060	0.20	RLBP1	retinaldehyde binding protein 1	44124	0.12
chr5_14298302_14298453	0.20	TRIO	trio Rho guanine nucleotide exchange factor	7291	0.33
chr6_160041713_160041864	0.20	SOD2	superoxide dismutase 2, mitochondrial	72472	0.09
chr21_46310753_46310904	0.20	PTTG1IP	pituitary tumor-transforming 1 interacting protein	17076	0.1
chr7_33080072_33080440	0.20	NT5C3A	5'-nucleotidase, cytosolic IIIA	265	0.9
chr11_9385409_9385962	0.20	IPO7	importin 7	20484	0.16
chr1_6086993_6087271	0.20	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	225	0.93
chr13_76867689_76867887	0.20	ENSG00000243274	.	158721	0.04
chr6_139870784_139870935	0.20	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	175102	0.03
chr11_35188283_35188434	0.20	CD44	CD44 molecule (Indian blood group)	9760	0.17
chr5_118609514_118610204	0.20	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	5410	0.21
chr22_32033546_32033968	0.20	PISD	phosphatidylserine decarboxylase	634	0.74
chr14_35092634_35092920	0.20	SNX6	sorting nexin 6	6101	0.2
chr18_3602703_3603732	0.20	DLGAP1-AS2	DLGAP1 antisense RNA 2	219	0.92
chr16_89429989_89430201	0.20	ANKRD11	ankyrin repeat domain 11	34701	0.1
chr7_20255346_20255644	0.20	MACC1	metastasis associated in colon cancer 1	1518	0.49
chr10_8099206_8099457	0.20	GATA3	GATA binding protein 3	2562	0.44
chr9_94186787_94187440	0.20	NFIL3	nuclear factor, interleukin 3 regulated	969	0.69
chr15_27495001_27495152	0.20	GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	21613	0.2
chr11_35061934_35062494	0.20	PDHX	pyruvate dehydrogenase complex, component X	62883	0.1
chr1_162667094_162667245	0.20	DDR2	discoidin domain receptor tyrosine kinase 2	64909	0.1
chr7_73119920_73120071	0.20	ENSG00000265724	.	5652	0.11
chrX_149352977_149353128	0.20	ENSG00000252454	.	43187	0.19
chr1_51069078_51069376	0.20	FAF1	Fas (TNFRSF6) associated factor 1	8943	0.23
chr4_166361643_166362016	0.20	CPE	carboxypeptidase E	22451	0.23
chr9_128441842_128441993	0.20	MAPKAP1	mitogen-activated protein kinase associated protein 1	6995	0.28
chrX_48917537_48917688	0.19	CCDC120	coiled-coil domain containing 120	1066	0.3
chr9_132648263_132648472	0.19	FNBP1	formin binding protein 1	33222	0.12
chr1_9399387_9399538	0.19	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	12028	0.22
chr5_158611818_158612659	0.19	RNF145	ring finger protein 145	22404	0.16
chr19_42388528_42389094	0.19	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	296	0.84
chr14_33883349_33883500	0.19	NPAS3	neuronal PAS domain protein 3	198906	0.03
chr12_3277666_3277860	0.19	TSPAN9-IT1	TSPAN9 intronic transcript 1 (non-protein coding)	18800	0.21
chr10_134330839_134330990	0.19	LINC01165	long intergenic non-protein coding RNA 1165	5039	0.22
chrX_40294011_40294465	0.19	ENSG00000206677	.	57854	0.14
chr19_34311073_34311611	0.19	KCTD15	potassium channel tetramerization domain containing 15	13513	0.27
chr6_34071312_34071463	0.19	GRM4	glutamate receptor, metabotropic 4	244	0.94
chr16_88837085_88837352	0.19	PIEZO1	piezo-type mechanosensitive ion channel component 1	14401	0.08
chr22_46929020_46929201	0.19	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1	2081	0.33
chr1_6659470_6659968	0.19	KLHL21	kelch-like family member 21	157	0.92
chr9_127023581_127024115	0.19	NEK6	NIMA-related kinase 6	96	0.82
chr9_132251498_132251652	0.19	ENSG00000264298	.	10740	0.21
chr3_122486679_122486830	0.19	ENSG00000238480	.	17535	0.17
chr19_2169086_2169237	0.19	DOT1L	DOT1-like histone H3K79 methyltransferase	4977	0.13
chr17_56410108_56410593	0.19	MIR142	microRNA 142	481	0.66
chr8_128911768_128911919	0.19	TMEM75	transmembrane protein 75	48748	0.14
chr7_33078848_33079779	0.19	NT5C3A	5'-nucleotidase, cytosolic IIIA	1208	0.42
chr19_39889302_39889453	0.19	MED29	mediator complex subunit 29	7325	0.08
chr2_111875565_111875871	0.19	BCL2L11	BCL2-like 11 (apoptosis facilitator)	1237	0.5
chr2_70224516_70224667	0.19	PCBP1-AS1	PCBP1 antisense RNA 1	618	0.69

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.2	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.1	0.2	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.2	GO:0018101	protein citrullination(GO:0018101)
0.1	0.3	GO:0071501	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	0.2	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1	0.2	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1	0.3	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.2	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0003181	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.1	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0046021	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.2	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.4	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.1	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.2	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:2001280	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0048343	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.3	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.3	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.0	GO:0043096	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.0	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.0	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0048841	regulation of axon extension involved in axon guidance(GO:0048841)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.0	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0098900	regulation of action potential(GO:0098900)
0.0	0.0	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0	0.1	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.0	GO:0002885	positive regulation of hypersensitivity(GO:0002885)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.1	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.0	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.0	GO:1902931	negative regulation of alcohol biosynthetic process(GO:1902931)
0.0	0.0	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0051043	regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0060992	response to fungicide(GO:0060992)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.2	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0009309	amine biosynthetic process(GO:0009309)
0.0	0.3	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.0	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.0	GO:0051136	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.3	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.1	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.0	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.2	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.0	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:2001235	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.0	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.0	0.0	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0071331	cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0	0.1	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.0	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.0	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.0	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.5	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.4	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.2	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.2	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.0	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.2	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.4	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0001846	opsonin binding(GO:0001846)
0.0	0.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.7	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.7	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0035240	dopamine binding(GO:0035240)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.0	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0032129	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.6	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	PID IGF1 PATHWAY	IGF1 pathway
0.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.3	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.1	PID TRAIL PATHWAY	TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.3	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras