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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FOXA3_FOXC2

Z-value: 0.63

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol Gene ID Gene Info
FOXA3
ENSG00000170608.2 FOXA3
FOXC2
ENSG00000176692.4 FOXC2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
FOXA3chr19_46367107_46367258650.893066-0.501.7e-01Click!
FOXC2chr16_86597596_8659808630160.2000960.836.1e-03Click!
FOXC2chr16_86599673_8659984910960.3898880.599.6e-02Click!
FOXC2chr16_86599475_8659964212990.3430270.531.4e-01Click!
FOXC2chr16_86599945_866001518090.4842870.501.7e-01Click!
FOXC2chr16_86597297_8659748734650.1888030.481.9e-01Click!

Activity of the FOXA3_FOXC2 motif across conditions

Conditions sorted by the z-value of the FOXA3_FOXC2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_107738861_107739281 0.39 OXR1
 oxidation resistance 1
 658
 0.71
chr11_57529774_57530544 0.25 CTNND1
 catenin (cadherin-associated protein), delta 1
 869
 0.5
chr3_167811230_167811432 0.23 GOLIM4
 golgi integral membrane protein 4
 1801
 0.51
chr8_15398472_15398721 0.23 TUSC3
 tumor suppressor candidate 3
 804
 0.72
chr6_44510355_44510599 0.22 ENSG00000266619
 .
 107099
 0.06
chr15_96869491_96869741 0.20 NR2F2
 nuclear receptor subfamily 2, group F, member 2
 449
 0.57
chr15_55574890_55575291 0.20 RAB27A
 RAB27A, member RAS oncogene family
 6911
 0.2
chr7_25109217_25109438 0.19 CYCS
 cytochrome c, somatic
 55541
 0.14
chr5_72746721_72747193 0.19 FOXD1
 forkhead box D1
 2605
 0.29
chr9_120466546_120467060 0.19 TLR4
 toll-like receptor 4
 153
 0.96
chr7_19152184_19152434 0.18 AC003986.6
212
 0.92
chr13_33803329_33803516 0.18 STARD13
 StAR-related lipid transfer (START) domain containing 13
 23279
 0.2
chr6_116833589_116833880 0.17 TRAPPC3L
 trafficking protein particle complex 3-like
 228
 0.83
chr5_52098501_52098716 0.16 CTD-2288O8.1
14748
 0.19
chr21_28214648_28215240 0.16 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 393
 0.9
chr14_75744052_75744985 0.16 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 959
 0.51
chr9_128235766_128235975 0.16 MAPKAP1
 mitogen-activated protein kinase associated protein 1
 10910
 0.23
chrX_10737482_10738236 0.15 MID1
 midline 1 (Opitz/BBB syndrome)
 92080
 0.1
chr20_9049623_9049963 0.15 PLCB4
 phospholipase C, beta 4
 45
 0.98
chr2_160470923_160471074 0.15 AC009506.1
809
 0.5
chr14_33409166_33409451 0.15 NPAS3
 neuronal PAS domain protein 3
 785
 0.79
chr3_132036571_132036865 0.15 ACPP
 acid phosphatase, prostate
 467
 0.84
chr21_36337524_36338023 0.14 RUNX1
 runt-related transcription factor 1
 75686
 0.12
chr7_48284393_48284544 0.14 ABCA13
 ATP-binding cassette, sub-family A (ABC1), member 13
 73411
 0.12
chr20_9048816_9049419 0.14 PLCB4
 phospholipase C, beta 4
 293
 0.9
chr3_100711576_100712203 0.14 ABI3BP
 ABI family, member 3 (NESH) binding protein
 408
 0.89
chr7_94025115_94025296 0.14 COL1A2
 collagen, type I, alpha 2
 1332
 0.57
chr10_112411260_112411724 0.14 RBM20
 RNA binding motif protein 20
 7337
 0.16
chr10_15126072_15126273 0.14 ACBD7
 acyl-CoA binding domain containing 7
 4603
 0.18
chr19_45995836_45996758 0.14 RTN2
 reticulon 2
 228
 0.87
chr7_19308580_19308778 0.14 FERD3L
 Fer3-like bHLH transcription factor
 123635
 0.05
chrX_10919281_10919504 0.14 MID1
 midline 1 (Opitz/BBB syndrome)
 67619
 0.14
chr1_158969050_158969253 0.13 IFI16
 interferon, gamma-inducible protein 16
 607
 0.76
chr2_190041307_190041749 0.13 COL5A2
 collagen, type V, alpha 2
 3077
 0.31
chr6_123039012_123039239 0.13 PKIB
 protein kinase (cAMP-dependent, catalytic) inhibitor beta
 418
 0.87
chr6_116719287_116719943 0.13 DSE
 dermatan sulfate epimerase
 27505
 0.14
chr12_64773878_64774029 0.13 C12orf56
 chromosome 12 open reading frame 56
 10353
 0.17
chr12_32688080_32688676 0.13 FGD4
 FYVE, RhoGEF and PH domain containing 4
 1120
 0.61
chr6_152085356_152085807 0.13 ESR1
 estrogen receptor 1
 39985
 0.18
chr6_151648337_151648657 0.13 AKAP12
 A kinase (PRKA) anchor protein 12
 1674
 0.27
chr8_108509086_108509237 0.12 ANGPT1
 angiopoietin 1
 1077
 0.7
chr4_109542934_109543085 0.12 RPL34
 ribosomal protein L34
 1197
 0.48
chr5_59109781_59109932 0.12 PDE4D
 phosphodiesterase 4D, cAMP-specific
 45385
 0.2
chr20_1783216_1783652 0.12 SIRPA
 signal-regulatory protein alpha
 91720
 0.07
chr4_16954347_16954651 0.12 LDB2
 LIM domain binding 2
 54067
 0.18
chr9_12882418_12882702 0.12 ENSG00000222658
 .
 2760
 0.36
chr5_59893443_59893927 0.12 DEPDC1B
 DEP domain containing 1B
 102276
 0.07
chr2_68465061_68465212 0.12 ENSG00000216115
 .
 8078
 0.14
chr1_196620715_196621368 0.12 CFH
 complement factor H
 33
 0.98
chr3_133461579_133461730 0.12 TF
 transferrin
 3146
 0.23
chr1_36275039_36275190 0.12 AGO4
 argonaute RISC catalytic component 4
 1341
 0.43
chr16_4104228_4104558 0.12 RP11-462G12.4
22380
 0.19
chr18_65983753_65984295 0.12 TMX3
 thioredoxin-related transmembrane protein 3
 398270
 0.01
chr4_67430868_67431028 0.12 ENSG00000221563
 .
 288406
 0.01
chr11_16023597_16024065 0.12 CTD-3096P4.1
20905
 0.28
chr2_150418995_150419256 0.12 AC144449.1
24585
 0.19
chr4_123795073_123795451 0.12 RP11-170N16.3
10605
 0.18
chr7_134464463_134465343 0.12 CALD1
 caldesmon 1
 474
 0.89
chr3_120168709_120169860 0.12 FSTL1
 follistatin-like 1
 554
 0.84
chr6_28175094_28175274 0.12 ZSCAN9
 zinc finger and SCAN domain containing 9
 17480
 0.12
chr4_87503159_87503484 0.12 MAPK10
 mitogen-activated protein kinase 10
 11942
 0.21
chr5_88030067_88030282 0.12 CTC-467M3.2
41706
 0.16
chr4_81392876_81393298 0.12 C4orf22
 chromosome 4 open reading frame 22
 136164
 0.05
chr2_157323604_157323795 0.11 GPD2
 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
 6385
 0.22
chr5_90515283_90515434 0.11 ENSG00000199643
 .
 51186
 0.18
chr2_145268671_145269078 0.11 ZEB2
 zinc finger E-box binding homeobox 2
 6241
 0.26
chr6_8083977_8084191 0.11 EEF1E1
 eukaryotic translation elongation factor 1 epsilon 1
 13460
 0.22
chr12_81472525_81472676 0.11 ACSS3
 acyl-CoA synthetase short-chain family member 3
 764
 0.72
chr6_98074983_98075489 0.11 MMS22L
 MMS22-like, DNA repair protein
 344184
 0.01
chr5_67294562_67294875 0.11 ENSG00000223149
 .
 31445
 0.24
chr10_4285552_4285907 0.11 ENSG00000207124
 .
 271415
 0.02
chr7_80928308_80928745 0.11 AC005008.2
 Uncharacterized protein
 111420
 0.08
chr1_158087708_158088406 0.11 KIRREL
 kin of IRRE like (Drosophila)
 31587
 0.18
chr15_77710162_77710461 0.11 PEAK1
 pseudopodium-enriched atypical kinase 1
 2131
 0.32
chr18_32290997_32291170 0.11 DTNA
 dystrobrevin, alpha
 822
 0.73
chr17_60868253_60868692 0.11 MARCH10
 membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
 15529
 0.23
chr18_67964238_67964389 0.11 SOCS6
 suppressor of cytokine signaling 6
 478
 0.85
chr5_141980216_141980760 0.11 AC005592.2
19075
 0.18
chr7_30516381_30516532 0.11 NOD1
 nucleotide-binding oligomerization domain containing 1
 1796
 0.37
chr1_243414977_243415342 0.11 CEP170
 centrosomal protein 170kDa
 1463
 0.39
chr7_151328064_151328292 0.11 PRKAG2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 1261
 0.55
chr15_61044545_61044696 0.11 RP11-554D20.1
11485
 0.22
chr3_137801110_137801644 0.11 DZIP1L
 DAZ interacting zinc finger protein 1-like
 14895
 0.2
chr11_10627928_10628217 0.11 MRVI1-AS1
 MRVI1 antisense RNA 1
 13328
 0.17
chr5_95595176_95595327 0.11 ENSG00000206997
 .
 49320
 0.17
chr6_141884450_141884959 0.11 ENSG00000222764
 .
 77155
 0.13
chr12_23088184_23088587 0.11 ETNK1
 ethanolamine kinase 1
 310094
 0.01
chr5_82770538_82771175 0.11 VCAN
 versican
 3112
 0.37
chr2_216296824_216297216 0.10 FN1
 fibronectin 1
 3770
 0.26
chr10_4541408_4541559 0.10 ENSG00000207124
 .
 15661
 0.3
chr21_40203900_40204051 0.10 ETS2
 v-ets avian erythroblastosis virus E26 oncogene homolog 2
 22415
 0.24
chr3_162003818_162003969 0.10 OTOL1
 otolin 1
 789297
 0.0
chr11_61890885_61891204 0.10 INCENP
 inner centromere protein antigens 135/155kDa
 401
 0.85
chr18_37421234_37421672 0.10 ENSG00000212354
 .
 162867
 0.04
chr12_32687758_32688027 0.10 FGD4
 FYVE, RhoGEF and PH domain containing 4
 634
 0.8
chr1_202428982_202429290 0.10 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
 2735
 0.3
chr8_2094260_2094411 0.10 MYOM2
 myomesin 2
 101151
 0.08
chr9_97951408_97952029 0.10 ENSG00000238746
 .
 16838
 0.19
chrX_15934152_15934303 0.10 ENSG00000200566
 .
 199
 0.96
chr1_183791724_183791999 0.10 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
 17571
 0.24
chr4_159857577_159857754 0.10 ENSG00000221314
 .
 63777
 0.11
chr2_106260790_106261225 0.10 NCK2
 NCK adaptor protein 2
 100347
 0.08
chr9_112513666_112514004 0.10 RP11-406O23.2
20488
 0.16
chr6_128828944_128829440 0.10 RP1-86D1.4
2922
 0.22
chr2_180427189_180427340 0.10 ZNF385B
 zinc finger protein 385B
 51
 0.99
chr10_126843486_126843769 0.10 CTBP2
 C-terminal binding protein 2
 3658
 0.35
chr9_16626345_16626809 0.10 RP11-62F24.1
903
 0.71
chr3_36954201_36954545 0.10 TRANK1
 tetratricopeptide repeat and ankyrin repeat containing 1
 32175
 0.17
chr9_935405_935889 0.10 DMRT3
 doublesex and mab-3 related transcription factor 3
 41317
 0.17
chr15_99864758_99865035 0.10 AC022819.2
 Uncharacterized protein
 5068
 0.23
chr8_48297219_48297488 0.10 SPIDR
 scaffolding protein involved in DNA repair
 55610
 0.16
chr7_90224844_90225183 0.10 AC002456.2
49
 0.94
chr6_143995099_143995343 0.10 PHACTR2
 phosphatase and actin regulator 2
 3881
 0.32
chr2_188416841_188416992 0.10 AC007319.1
1960
 0.34
chr5_124082726_124083211 0.10 ZNF608
 zinc finger protein 608
 648
 0.62
chr10_116639288_116639471 0.10 FAM160B1
 family with sequence similarity 160, member B1
 18829
 0.24
chr18_52763849_52764148 0.10 ENSG00000252437
 .
 49878
 0.16
chr3_63908711_63908862 0.10 ATXN7
 ataxin 7
 10511
 0.18
chr6_45523679_45523878 0.10 ENSG00000252738
 .
 90063
 0.09
chr18_55890673_55891004 0.10 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 2035
 0.39
chr9_22883230_22883381 0.10 ENSG00000265572
 .
 69797
 0.14
chr17_68164439_68165051 0.10 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
 69
 0.94
chr15_53072694_53072932 0.10 ONECUT1
 one cut homeobox 1
 567
 0.84
chr9_22007341_22007594 0.09 CDKN2B
 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
 1485
 0.34
chr12_91575790_91576058 0.09 DCN
 decorin
 505
 0.87
chr7_72991877_72992028 0.09 TBL2
 transducin (beta)-like 2
 714
 0.6
chr14_74551356_74551507 0.09 LIN52
 lin-52 homolog (C. elegans)
 68
 0.72
chr2_127983002_127983353 0.09 CYP27C1
 cytochrome P450, family 27, subfamily C, polypeptide 1
 5523
 0.25
chr7_3632163_3632314 0.09 AC011284.3
51178
 0.18
chr3_171685206_171685443 0.09 FNDC3B
 fibronectin type III domain containing 3B
 72094
 0.1
chr18_72880123_72880274 0.09 ZADH2
 zinc binding alcohol dehydrogenase domain containing 2
 37270
 0.19
chr1_87254203_87254481 0.09 SH3GLB1
 SH3-domain GRB2-like endophilin B1
 83764
 0.08
chr10_4284322_4284712 0.09 ENSG00000207124
 .
 272627
 0.02
chr17_38604976_38605127 0.09 IGFBP4
 insulin-like growth factor binding protein 4
 5338
 0.15
chr5_38550048_38550208 0.09 LIFR
 leukemia inhibitory factor receptor alpha
 6610
 0.18
chr6_140525151_140525313 0.09 ENSG00000263514
 .
 1157
 0.62
chr6_71972702_71972953 0.09 RP11-154D6.1
21808
 0.19
chr6_112823116_112823311 0.09 ENSG00000239095
 .
 25285
 0.2
chr21_43316610_43316761 0.09 C2CD2
 C2 calcium-dependent domain containing 2
 5076
 0.15
chr4_129557030_129557181 0.09 ENSG00000238802
 .
 120076
 0.06
chr3_120361749_120361900 0.09 HGD
 homogentisate 1,2-dioxygenase
 3358
 0.3
chr7_143581670_143581927 0.09 FAM115A
 family with sequence similarity 115, member A
 665
 0.7
chr2_179032632_179032866 0.09 ENSG00000223096
 .
 25474
 0.16
chr10_28015309_28015460 0.09 MKX
 mohawk homeobox
 17090
 0.2
chr3_15370902_15371053 0.09 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 3090
 0.19
chr3_138594988_138595139 0.09 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 41283
 0.15
chr6_82496917_82497068 0.09 ENSG00000206886
 .
 23251
 0.2
chr8_96820368_96820519 0.09 ENSG00000223297
 .
 129300
 0.06
chr1_98369641_98369792 0.09 DPYD
 dihydropyrimidine dehydrogenase
 16837
 0.28
chr6_45296305_45296528 0.09 RUNX2
 runt-related transcription factor 2
 48
 0.98
chr7_74293974_74294125 0.09 STAG3L2
 stromal antigen 3-like 2 (pseudogene)
 10469
 0.18
chr10_123469524_123469675 0.09 RP11-78A18.2
26219
 0.24
chr3_64199959_64200146 0.09 PRICKLE2
 prickle homolog 2 (Drosophila)
 11079
 0.21
chr9_128484739_128484890 0.09 MAPKAP1
 mitogen-activated protein kinase associated protein 1
 15301
 0.23
chr14_79747812_79748200 0.09 NRXN3
 neurexin 3
 1757
 0.44
chr4_134071254_134071890 0.09 PCDH10
 protocadherin 10
 1102
 0.7
chr4_57276664_57276969 0.09 AC068620.1
 Uncharacterized protein
 134
 0.95
chr10_17278277_17278428 0.09 RP11-124N14.3
1520
 0.34
chr1_186472613_186472786 0.09 PDC
 phosducin
 42445
 0.15
chr1_81703498_81704139 0.09 ENSG00000223026
 .
 13656
 0.28
chr4_186577993_186578477 0.09 SORBS2
 sorbin and SH3 domain containing 2
 112
 0.97
chr11_13204755_13204972 0.09 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
 93336
 0.09
chr6_150177526_150177677 0.09 RP11-350J20.12
4003
 0.14
chr15_39881812_39881998 0.09 CTD-2033D15.1
4527
 0.21
chr2_201473941_201474433 0.09 AOX1
 aldehyde oxidase 1
 21290
 0.2
chr12_75876585_75876939 0.09 GLIPR1
 GLI pathogenesis-related 1
 1778
 0.34
chr9_89808674_89808967 0.09 C9orf170
 chromosome 9 open reading frame 170
 45261
 0.18
chr20_1103594_1103745 0.09 PSMF1
 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
 4389
 0.25
chr6_72205767_72206133 0.09 ENSG00000212099
 .
 42729
 0.17
chr18_60774564_60774715 0.09 RP11-299P2.1
43914
 0.17
chr4_48701412_48701950 0.09 FRYL
 FRY-like
 18493
 0.24
chr4_169553568_169553728 0.09 PALLD
 palladin, cytoskeletal associated protein
 880
 0.63
chr5_115790032_115790655 0.09 CTB-118N6.3
4917
 0.26
chr1_151653168_151653448 0.09 RP11-98D18.1
20194
 0.08
chr10_54357230_54357516 0.09 RP11-556E13.1
36508
 0.23
chr2_63416100_63416251 0.09 OTX1
 orthodenticle homeobox 1
 138238
 0.05
chr11_86085513_86085741 0.09 CCDC81
 coiled-coil domain containing 81
 151
 0.96
chr1_116665777_116665975 0.09 MAB21L3
 mab-21-like 3 (C. elegans)
 11500
 0.27
chr5_121417237_121417571 0.09 LOX
 lysyl oxidase
 3424
 0.28
chr9_14098246_14098397 0.08 NFIB
 nuclear factor I/B
 82470
 0.11
chr5_74634021_74634424 0.08 HMGCR
 3-hydroxy-3-methylglutaryl-CoA reductase
 264
 0.89
chr3_25471806_25472309 0.08 RARB
 retinoic acid receptor, beta
 2255
 0.41
chr4_115282272_115282768 0.08 UGT8
 UDP glycosyltransferase 8
 237091
 0.02
chr15_48959812_48960090 0.08 FBN1
 fibrillin 1
 21905
 0.23
chr11_60926256_60926465 0.08 VPS37C
 vacuolar protein sorting 37 homolog C (S. cerevisiae)
 2248
 0.27
chr1_119529921_119530106 0.08 TBX15
 T-box 15
 415
 0.9
chr7_82057700_82058025 0.08 CACNA2D1
 calcium channel, voltage-dependent, alpha 2/delta subunit 1
 15169
 0.3
chr3_105584255_105584406 0.08 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 3557
 0.4
chr2_28189640_28189791 0.08 ENSG00000265321
 .
 29519
 0.18
chr4_96455327_96455478 0.08 UNC5C
 unc-5 homolog C (C. elegans)
 14721
 0.24
chr6_19465542_19465832 0.08 ENSG00000201523
 .
 27173
 0.27
chr2_224445554_224445715 0.08 SCG2
 secretogranin II
 21368
 0.28
chr15_96883311_96883827 0.08 ENSG00000222651
 .
 7079
 0.16
chr12_115174256_115174747 0.08 ENSG00000252459
 .
 1008
 0.64
chr4_138585410_138585827 0.08 PCDH18
 protocadherin 18
 131970
 0.06
chr12_94132814_94133007 0.08 RP11-887P2.5
1311
 0.51
chr3_43337483_43337634 0.08 SNRK
 SNF related kinase
 9480
 0.18
chr2_128491676_128491827 0.08 SFT2D3
 SFT2 domain containing 3
 33154
 0.13
chr8_9409853_9410128 0.08 TNKS
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
 3434
 0.27
chr4_186696107_186696537 0.08 SORBS2
 sorbin and SH3 domain containing 2
 108
 0.98

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.0 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0060841 venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:0042321 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0 0.0 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.0 GO:0072071 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels