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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for FOXC1

Z-value: 0.81

Motif logo

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Transcription factors associated with FOXC1

Gene Symbol Gene ID Gene Info
FOXC1
ENSG00000054598.5 forkhead box C1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_1885704_1885932FOXC12751370.0149660.703.7e-02Click!
chr6_1703862_1704013FOXC1932560.093857-0.581.0e-01Click!
chr6_1617814_1617965FOXC172080.3141620.571.1e-01Click!
chr6_1615364_1615572FOXC147870.3368130.561.1e-01Click!
chr6_1610269_1610509FOXC12920.9475490.561.2e-01Click!

Activity of the FOXC1 motif across conditions

Conditions sorted by the z-value of the FOXC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chrX_16826274_16826456 0.43 TXLNG
 taxilin gamma
 21810
 0.16
chr7_6521360_6521521 0.39 FLJ20306
 CDNA FLJ20306 fis, clone HEP06881; Putative uncharacterized protein FLJ20306; Uncharacterized protein
 1482
 0.28
chr11_82828119_82828301 0.39 PCF11
 PCF11 cleavage and polyadenylation factor subunit
 39820
 0.12
chr11_3400503_3400805 0.35 ZNF195
 zinc finger protein 195
 206
 0.92
chr8_27631557_27631733 0.34 ESCO2
 establishment of sister chromatid cohesion N-acetyltransferase 2
 258
 0.66
chr8_77911562_77912296 0.33 PEX2
 peroxisomal biogenesis factor 2
 533
 0.85
chr9_71590240_71590555 0.32 PRKACG
 protein kinase, cAMP-dependent, catalytic, gamma
 38642
 0.15
chr7_84154352_84154503 0.28 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 32387
 0.25
chr11_92930195_92930700 0.27 SLC36A4
 solute carrier family 36 (proton/amino acid symporter), member 4
 174
 0.97
chr1_98369641_98369792 0.26 DPYD
 dihydropyrimidine dehydrogenase
 16837
 0.28
chr6_1612835_1613496 0.26 FOXC1
 forkhead box C1
 2484
 0.42
chr11_119076374_119076525 0.25 CBL
 Cbl proto-oncogene, E3 ubiquitin protein ligase
 303
 0.81
chr12_75876585_75876939 0.25 GLIPR1
 GLI pathogenesis-related 1
 1778
 0.34
chr4_129557030_129557181 0.25 ENSG00000238802
 .
 120076
 0.06
chr11_46615706_46615915 0.24 AMBRA1
 autophagy/beclin-1 regulator 1
 135
 0.96
chr10_50649676_50649900 0.23 RP11-123B3.2
22465
 0.17
chr12_72667945_72668096 0.23 ENSG00000236333
 .
 667
 0.5
chr14_31879360_31879511 0.23 HEATR5A
 HEAT repeat containing 5A
 7254
 0.17
chr8_13730073_13730224 0.23 RP11-145O15.3
268029
 0.02
chr15_76629589_76629763 0.22 ISL2
 ISL LIM homeobox 2
 611
 0.74
chrX_15934152_15934303 0.21 ENSG00000200566
 .
 199
 0.96
chr15_91955379_91955670 0.21 SV2B
 synaptic vesicle glycoprotein 2B
 186424
 0.03
chr6_116833589_116833880 0.21 TRAPPC3L
 trafficking protein particle complex 3-like
 228
 0.83
chr19_2095175_2095486 0.21 MOB3A
 MOB kinase activator 3A
 939
 0.33
chr2_113012718_113012869 0.21 ZC3H8
 zinc finger CCCH-type containing 8
 105
 0.97
chr10_91061669_91062419 0.20 IFIT2
 interferon-induced protein with tetratricopeptide repeats 2
 332
 0.85
chrY_9925657_9925808 0.20 ENSG00000251766
 .
 2405
 0.28
chr16_2570012_2570182 0.20 AMDHD2
 amidohydrolase domain containing 2
 261
 0.71
chr11_46141542_46141818 0.20 PHF21A
 PHD finger protein 21A
 267
 0.92
chrX_18456912_18457063 0.20 CDKL5
 cyclin-dependent kinase-like 5
 3321
 0.31
chr11_104576737_104577140 0.20 CASP12
 caspase 12 (gene/pseudogene)
 192203
 0.03
chr1_28832516_28832718 0.19 RCC1
 regulator of chromosome condensation 1
 48
 0.94
chr10_8203120_8203271 0.19 GATA3
 GATA binding protein 3
 106426
 0.08
chr2_72376882_72377179 0.19 CYP26B1
 cytochrome P450, family 26, subfamily B, polypeptide 1
 1863
 0.53
chr5_158407500_158407684 0.19 CTD-2363C16.1
2422
 0.33
chr6_2876062_2876267 0.19 ENSG00000266750
 .
 21823
 0.15
chr4_10691726_10691877 0.19 CLNK
 cytokine-dependent hematopoietic cell linker
 5312
 0.35
chr1_39324368_39325146 0.19 RRAGC
 Ras-related GTP binding C
 738
 0.44
chr5_56124620_56124771 0.19 MAP3K1
 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
 13294
 0.17
chr11_15919049_15919200 0.18 CTD-3096P4.1
125612
 0.06
chr7_147748643_147748794 0.18 CNTNAP2
 contactin associated protein-like 2
 82058
 0.1
chr19_4114935_4115086 0.18 MAP2K2
 mitogen-activated protein kinase kinase 2
 9104
 0.12
chr4_169075013_169075164 0.18 RP11-310I9.1
40606
 0.17
chr18_21032782_21033062 0.18 RIOK3
 RIO kinase 3
 135
 0.95
chr2_61372387_61372598 0.18 C2orf74
 chromosome 2 open reading frame 74
 249
 0.92
chr5_17255187_17255338 0.18 ENSG00000252908
 .
 14542
 0.19
chr6_132833581_132834005 0.18 STX7
 syntaxin 7
 408
 0.85
chr14_52116783_52117087 0.17 FRMD6
 FERM domain containing 6
 1641
 0.39
chr6_156086673_156086824 0.17 ENSG00000238789
 .
 110588
 0.07
chr11_57529774_57530544 0.17 CTNND1
 catenin (cadherin-associated protein), delta 1
 869
 0.5
chr4_7937771_7938061 0.17 AC097381.1
2812
 0.26
chr8_126444680_126445315 0.17 TRIB1
 tribbles pseudokinase 1
 546
 0.81
chr12_91574306_91575101 0.17 DCN
 decorin
 50
 0.99
chr19_19932661_19932812 0.17 ZNF506
 zinc finger protein 506
 176
 0.93
chr5_82672808_82672959 0.17 VCAN
 versican
 94401
 0.09
chr12_77626162_77626313 0.17 ENSG00000238769
 .
 69432
 0.14
chr14_61190612_61190839 0.17 SIX4
 SIX homeobox 4
 127
 0.97
chr19_42985275_42985426 0.17 ENSG00000253048
 .
 8323
 0.14
chr14_75744052_75744985 0.16 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 959
 0.51
chr7_116775065_116775216 0.16 ST7-AS2
 ST7 antisense RNA 2
 10472
 0.23
chr14_37463384_37463535 0.16 ENSG00000266327
 .
 41863
 0.18
chr7_24608273_24608424 0.16 MPP6
 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
 4539
 0.29
chr20_17005032_17005183 0.16 ENSG00000212165
 .
 41429
 0.2
chr10_63855843_63855994 0.16 ENSG00000221094
 .
 20056
 0.23
chr3_79778551_79778702 0.16 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
 38339
 0.23
chr13_24841248_24841663 0.16 SPATA13
 spermatogenesis associated 13
 3371
 0.21
chr5_54157434_54157674 0.16 ENSG00000221073
 .
 8778
 0.26
chr1_64977055_64977206 0.16 CACHD1
 cache domain containing 1
 40655
 0.18
chr5_369067_369218 0.16 AHRR
 aryl-hydrocarbon receptor repressor
 25499
 0.15
chr18_47793998_47794618 0.16 CCDC11
 coiled-coil domain containing 11
 1416
 0.36
chr2_216293163_216293314 0.16 FN1
 fibronectin 1
 7552
 0.23
chr8_59466247_59466777 0.16 SDCBP
 syndecan binding protein (syntenin)
 698
 0.76
chr7_134287566_134287824 0.16 AKR1B15
 aldo-keto reductase family 1, member B15
 37462
 0.17
chr1_28879171_28879359 0.16 TRNAU1AP
 tRNA selenocysteine 1 associated protein 1
 332
 0.8
chr15_64923415_64923566 0.16 ENSG00000207223
 .
 21597
 0.14
chr9_128484739_128484890 0.16 MAPKAP1
 mitogen-activated protein kinase associated protein 1
 15301
 0.23
chr8_42005635_42005786 0.16 RP11-589C21.5
4571
 0.19
chr22_17697616_17697767 0.16 CECR1
 cat eye syndrome chromosome region, candidate 1
 2575
 0.29
chr13_27825183_27825382 0.15 RPL21
 ribosomal protein L21
 164
 0.92
chr19_16347709_16347860 0.15 AP1M1
 adaptor-related protein complex 1, mu 1 subunit
 9368
 0.15
chr6_159458069_159458220 0.15 TAGAP
 T-cell activation RhoGTPase activating protein
 7906
 0.19
chr3_187984346_187984497 0.15 LPP
 LIM domain containing preferred translocation partner in lipoma
 26769
 0.24
chr10_17826229_17826380 0.15 MRC1L1
 cDNA FLJ56855, highly similar to Macrophage mannose receptor 1
 25058
 0.16
chr20_5550410_5550561 0.15 GPCPD1
 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
 5669
 0.27
chr10_28822829_28823308 0.15 WAC
 WW domain containing adaptor with coiled-coil
 16
 0.97
chr7_93926282_93926700 0.15 COL1A2
 collagen, type I, alpha 2
 97382
 0.08
chr5_55339622_55339773 0.15 ENSG00000238326
 .
 43248
 0.11
chr5_37370451_37371178 0.15 NUP155
 nucleoporin 155kDa
 73
 0.98
chr7_70773511_70773662 0.15 ENSG00000265878
 .
 844
 0.58
chr5_15575280_15575431 0.15 CTD-2350J17.1
32003
 0.21
chr1_205144953_205145111 0.15 DSTYK
 dual serine/threonine and tyrosine protein kinase
 35662
 0.13
chr14_90863482_90863819 0.15 CALM1
 calmodulin 1 (phosphorylase kinase, delta)
 250
 0.92
chr3_31814428_31814579 0.15 OSBPL10-AS1
 OSBPL10 antisense RNA 1
 56020
 0.14
chr2_152146458_152146912 0.15 NMI
 N-myc (and STAT) interactor
 114
 0.97
chrX_80458564_80458878 0.15 SH3BGRL
 SH3 domain binding glutamic acid-rich protein like
 1279
 0.36
chr1_91748546_91748727 0.15 ENSG00000206817
 .
 21454
 0.25
chr12_56435716_56435907 0.15 RPS26
 ribosomal protein S26
 134
 0.6
chr14_23584164_23584381 0.15 CEBPE
 CCAAT/enhancer binding protein (C/EBP), epsilon
 4553
 0.11
chr9_97021933_97022185 0.14 ZNF169
 zinc finger protein 169
 449
 0.8
chr19_10927638_10927909 0.14 ENSG00000207752
 .
 399
 0.76
chr5_66255088_66255484 0.14 MAST4
 microtubule associated serine/threonine kinase family member 4
 470
 0.88
chr1_109935632_109935931 0.14 SORT1
 sortilin 1
 198
 0.93
chr3_119921742_119921893 0.14 ENSG00000206721
 .
 7350
 0.22
chr8_8395574_8395725 0.14 ENSG00000263616
 .
 44516
 0.17
chr9_20144272_20144623 0.14 ENSG00000221744
 .
 150555
 0.04
chr15_69110393_69110544 0.14 ANP32A
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 2757
 0.31
chr10_104926250_104926401 0.14 NT5C2
 5'-nucleotidase, cytosolic II
 8414
 0.23
chr7_148843913_148844354 0.14 ZNF398
 zinc finger protein 398
 427
 0.79
chr8_37556330_37556485 0.14 ZNF703
 zinc finger protein 703
 3138
 0.17
chr3_122513057_122513432 0.14 DIRC2
 disrupted in renal carcinoma 2
 398
 0.6
chr6_6592584_6592735 0.14 LY86
 lymphocyte antigen 86
 3757
 0.28
chr6_106583373_106583524 0.14 RP1-134E15.3
35433
 0.17
chr9_120466546_120467060 0.14 TLR4
 toll-like receptor 4
 153
 0.96
chr6_113012091_113012242 0.14 ENSG00000252215
 .
 158782
 0.04
chr5_179482246_179482397 0.14 RNF130
 ring finger protein 130
 16400
 0.19
chr1_236767249_236767530 0.14 HEATR1
 HEAT repeat containing 1
 399
 0.87
chr7_19308580_19308778 0.14 FERD3L
 Fer3-like bHLH transcription factor
 123635
 0.05
chr6_151597751_151597996 0.14 ENSG00000252431
 .
 3874
 0.18
chr21_34499350_34499501 0.14 AP000290.7
29513
 0.14
chr12_124043713_124043864 0.14 ENSG00000266655
 .
 22832
 0.11
chr5_133583428_133583579 0.14 PPP2CA
 protein phosphatase 2, catalytic subunit, alpha isozyme
 21670
 0.14
chr1_66797787_66798583 0.14 PDE4B
 phosphodiesterase 4B, cAMP-specific
 313
 0.94
chr13_30422824_30423057 0.14 UBL3
 ubiquitin-like 3
 1881
 0.48
chr17_42767403_42767760 0.14 CCDC43
 coiled-coil domain containing 43
 434
 0.75
chr5_98369155_98369504 0.14 ENSG00000200351
 .
 96878
 0.08
chr8_92051814_92052056 0.14 TMEM55A
 transmembrane protein 55A
 1128
 0.39
chr6_79788058_79788292 0.13 PHIP
 pleckstrin homology domain interacting protein
 222
 0.96
chr2_144565732_144565883 0.13 CTD-2252P21.1
32165
 0.19
chr11_94226416_94226932 0.13 ANKRD49
 ankyrin repeat domain 49
 121
 0.73
chr22_17651901_17652140 0.13 CECR5
 cat eye syndrome chromosome region, candidate 5
 5843
 0.17
chr1_95700160_95700399 0.13 RWDD3
 RWD domain containing 3
 512
 0.57
chr6_26365718_26366052 0.13 ENSG00000215979
 .
 105
 0.79
chr6_134694363_134694677 0.13 SGK1
 serum/glucocorticoid regulated kinase 1
 55270
 0.15
chr19_13278225_13278635 0.13 CTC-250I14.6
13423
 0.11
chr10_105595201_105595352 0.13 SH3PXD2A
 SH3 and PX domains 2A
 19888
 0.19
chr14_59106280_59106431 0.13 DACT1
 dishevelled-binding antagonist of beta-catenin 1
 800
 0.74
chr10_75646822_75647179 0.13 CAMK2G
 calcium/calmodulin-dependent protein kinase II gamma
 12657
 0.12
chr6_26125804_26126001 0.13 HIST1H2AC
 histone cluster 1, H2ac
 1471
 0.17
chr9_23190046_23190197 0.13 ENSG00000265572
 .
 237019
 0.02
chr18_10743903_10744054 0.13 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 4520
 0.28
chr5_173318326_173318892 0.13 CPEB4
 cytoplasmic polyadenylation element binding protein 4
 929
 0.69
chr1_66800579_66801197 0.12 PDE4B
 phosphodiesterase 4B, cAMP-specific
 3016
 0.39
chr10_14049890_14050132 0.12 FRMD4A
 FERM domain containing 4A
 521
 0.82
chr1_2164202_2164388 0.12 SKI
 v-ski avian sarcoma viral oncogene homolog
 4161
 0.15
chr16_48418037_48418576 0.12 SIAH1
 siah E3 ubiquitin protein ligase 1
 1055
 0.5
chr15_67803077_67803228 0.12 C15orf61
 chromosome 15 open reading frame 61
 10254
 0.21
chr11_67142318_67142469 0.12 CLCF1
 cardiotrophin-like cytokine factor 1
 745
 0.41
chr4_22239606_22240002 0.12 ENSG00000238383
 .
 111269
 0.07
chr6_56555605_56555856 0.12 DST
 dystonin
 47936
 0.18
chr1_221219794_221220024 0.12 HLX
 H2.0-like homeobox
 165325
 0.04
chr17_34891354_34891543 0.12 PIGW
 phosphatidylinositol glycan anchor biosynthesis, class W
 45
 0.91
chr1_159852065_159852216 0.12 RP11-190A12.8
15396
 0.08
chr1_150979434_150979585 0.12 FAM63A
 family with sequence similarity 63, member A
 176
 0.86
chr17_39471970_39472121 0.12 KRTAP17-1
 keratin associated protein 17-1
 98
 0.92
chrX_39501672_39501823 0.12 ENSG00000263730
 .
 18723
 0.29
chr11_122568313_122568557 0.12 ENSG00000239079
 .
 28584
 0.19
chr6_2222017_2222664 0.12 GMDS
 GDP-mannose 4,6-dehydratase
 23586
 0.28
chr5_123463412_123463801 0.12 CSNK1G3
 casein kinase 1, gamma 3
 539487
 0.0
chr7_92746852_92747341 0.12 SAMD9
 sterile alpha motif domain containing 9
 179
 0.96
chr9_127704164_127704315 0.12 GOLGA1
 golgin A1
 861
 0.6
chr3_15370902_15371053 0.12 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 3090
 0.19
chr20_42087283_42087478 0.12 SRSF6
 serine/arginine-rich splicing factor 6
 812
 0.56
chr2_25457035_25457186 0.12 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 18070
 0.19
chr22_18120777_18121028 0.12 BCL2L13
 BCL2-like 13 (apoptosis facilitator)
 454
 0.78
chr17_56709506_56709776 0.12 ENSG00000212195
 .
 444
 0.75
chr8_22525362_22525513 0.12 BIN3
 bridging integrator 3
 1189
 0.35
chr7_72772148_72772660 0.12 ENSG00000206709
 .
 19201
 0.13
chr5_140044777_140044956 0.12 WDR55
 WD repeat domain 55
 605
 0.47
chr16_67222162_67222313 0.12 EXOC3L1
 exocyst complex component 3-like 1
 1802
 0.13
chr6_6943480_6943659 0.12 ENSG00000240936
 .
 4439
 0.33
chr18_56168357_56168508 0.12 RP11-1151B14.4
34215
 0.13
chr1_205257217_205257368 0.12 TMCC2
 transmembrane and coiled-coil domain family 2
 31963
 0.12
chr20_56963544_56964018 0.11 VAPB
 VAMP (vesicle-associated membrane protein)-associated protein B and C
 397
 0.89
chr9_99776295_99776451 0.11 HIATL2
 hippocampus abundant transcript-like 2
 511
 0.83
chr12_75875359_75875792 0.11 GLIPR1
 GLI pathogenesis-related 1
 591
 0.74
chr12_53448318_53448482 0.11 RP11-983P16.4
178
 0.91
chrY_23354523_23354674 0.11 CYorf17
 chromosome Y open reading frame 17
 193648
 0.03
chr10_120789931_120790695 0.11 NANOS1
 nanos homolog 1 (Drosophila)
 375
 0.81
chr3_11278875_11279026 0.11 HRH1
 histamine receptor H1
 11233
 0.25
chr19_34286123_34286306 0.11 KCTD15
 potassium channel tetramerization domain containing 15
 624
 0.82
chr15_72665455_72665606 0.11 HEXA
 hexosaminidase A (alpha polypeptide)
 2655
 0.21
chr18_72880123_72880274 0.11 ZADH2
 zinc binding alcohol dehydrogenase domain containing 2
 37270
 0.19
chr4_24975617_24975768 0.11 CCDC149
 coiled-coil domain containing 149
 6078
 0.28
chr12_105502043_105502544 0.11 KIAA1033
 KIAA1033
 801
 0.5
chr4_162498417_162498568 0.11 RP11-234O6.2
198387
 0.03
chr2_192900733_192900884 0.11 AC098617.1
102
 0.98
chr14_89796844_89796995 0.11 RP11-356K23.1
19710
 0.18
chrX_3617821_3618286 0.11 PRKX
 protein kinase, X-linked
 13596
 0.21
chr4_15704055_15704284 0.11 BST1
 bone marrow stromal cell antigen 1
 404
 0.85
chr1_72749102_72749377 0.11 NEGR1
 neuronal growth regulator 1
 822
 0.78
chr17_21226277_21226442 0.11 MAP2K3
 mitogen-activated protein kinase kinase 3
 10905
 0.2
chr7_19152184_19152434 0.11 AC003986.6
212
 0.92
chr9_130504383_130504534 0.11 TOR2A
 torsin family 2, member A
 6854
 0.1
chr9_118918844_118919316 0.11 PAPPA
 pregnancy-associated plasma protein A, pappalysin 1
 2997
 0.34
chr3_58319217_58319933 0.11 PXK
 PX domain containing serine/threonine kinase
 542
 0.78
chr4_186696107_186696537 0.11 SORBS2
 sorbin and SH3 domain containing 2
 108
 0.98
chr21_26378043_26378194 0.11 ENSG00000232512
 .
 95327
 0.09
chr12_20141265_20141425 0.11 ENSG00000221679
 .
 15546
 0.3
chr13_31481253_31481536 0.11 MEDAG
 mesenteric estrogen-dependent adipogenesis
 551
 0.78
chr10_123469524_123469675 0.11 RP11-78A18.2
26219
 0.24

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.2 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0048342 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.2 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.3 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.1 GO:0046174 polyol catabolic process(GO:0046174)
0.0 0.3 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0042891 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.0 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0043923 positive regulation by host of viral transcription(GO:0043923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway