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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FOXJ2

Z-value: 1.65

Motif logo

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Transcription factors associated with FOXJ2

Gene Symbol Gene ID Gene Info
ENSG00000065970.4 FOXJ2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
FOXJ2chr12_8189890_819004140090.1863680.916.4e-04Click!
FOXJ2chr12_8187512_818770116500.323203-0.791.2e-02Click!
FOXJ2chr12_8179472_818000655600.1735470.561.1e-01Click!
FOXJ2chr12_8186552_81867576980.640546-0.511.6e-01Click!
FOXJ2chr12_8191182_819143853540.170227-0.452.3e-01Click!

Activity of the FOXJ2 motif across conditions

Conditions sorted by the z-value of the FOXJ2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_202127394_202127951 1.24 CASP8
caspase 8, apoptosis-related cysteine peptidase
993
0.56
chr1_198608588_198608957 1.15 PTPRC
protein tyrosine phosphatase, receptor type, C
480
0.86
chr20_47439188_47439680 1.09 PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
4986
0.3
chr12_54891959_54892179 1.09 NCKAP1L
NCK-associated protein 1-like
499
0.73
chr9_95728150_95728303 1.05 FGD3
FYVE, RhoGEF and PH domain containing 3
1983
0.37
chr10_11212356_11212648 1.04 RP3-323N1.2

837
0.65
chr2_198172097_198172605 1.02 ANKRD44
ankyrin repeat domain 44
3160
0.2
chr13_31310422_31310683 1.00 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
907
0.71
chr1_114413652_114413958 0.98 PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
515
0.69
chr8_27236494_27236808 0.98 PTK2B
protein tyrosine kinase 2 beta
1517
0.47
chr10_11217828_11218013 0.94 RP3-323N1.2

4581
0.25
chr17_43300272_43300459 0.93 CTD-2020K17.1

776
0.38
chr1_40526410_40526561 0.93 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
19931
0.16
chr14_22631434_22631696 0.92 ENSG00000238634
.
20678
0.25
chr9_71783775_71784020 0.91 TJP2
tight junction protein 2
5184
0.29
chr1_185663060_185663272 0.89 HMCN1
hemicentin 1
40517
0.17
chr11_59320728_59320879 0.86 ENSG00000252893
.
5470
0.14
chr6_20174159_20174424 0.84 RP11-239H6.2

38027
0.18
chr17_29639732_29640055 0.82 EVI2B
ecotropic viral integration site 2B
1209
0.36
chr12_25206187_25206540 0.82 LRMP
lymphoid-restricted membrane protein
689
0.71
chr4_70625524_70625675 0.80 SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
717
0.76
chr10_104926250_104926401 0.78 NT5C2
5'-nucleotidase, cytosolic II
8414
0.23
chr5_180231798_180232282 0.78 MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
1117
0.47
chr8_103991507_103991658 0.78 ENSG00000265898
.
18434
0.14
chr13_41372571_41372761 0.77 SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
5372
0.18
chrY_1605029_1605190 0.77 NA
NA
> 106
NA
chr13_41592877_41593136 0.77 ELF1
E74-like factor 1 (ets domain transcription factor)
444
0.84
chr12_120974205_120974387 0.77 RNF10
ring finger protein 10
1067
0.34
chr6_31802179_31802624 0.76 C6orf48
chromosome 6 open reading frame 48
3
0.87
chrX_1655035_1655190 0.76 P2RY8
purinergic receptor P2Y, G-protein coupled, 8
888
0.64
chr15_86126252_86126683 0.73 RP11-815J21.2

3058
0.23
chrX_70331541_70331692 0.71 IL2RG
interleukin 2 receptor, gamma
135
0.92
chr6_143165995_143166218 0.71 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
7922
0.29
chr6_159465648_159465970 0.71 TAGAP
T-cell activation RhoGTPase activating protein
241
0.93
chr11_6767215_6767876 0.70 OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
22741
0.11
chr2_158295494_158296053 0.70 CYTIP
cytohesin 1 interacting protein
153
0.96
chr22_43011256_43011463 0.69 ENSG00000270022
.
109
0.79
chr21_36474794_36475157 0.68 RUNX1
runt-related transcription factor 1
53334
0.18
chr9_139433599_139433867 0.68 RP11-413M3.4

3600
0.12
chrX_78407252_78407403 0.67 GPR174
G protein-coupled receptor 174
19142
0.29
chr19_42061527_42061721 0.67 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
5738
0.18
chr2_204801338_204802214 0.67 ICOS
inducible T-cell co-stimulator
273
0.95
chr8_134070006_134070389 0.66 SLA
Src-like-adaptor
2406
0.36
chr11_82828119_82828301 0.66 PCF11
PCF11 cleavage and polyadenylation factor subunit
39820
0.12
chr5_96152602_96152931 0.65 ERAP1
endoplasmic reticulum aminopeptidase 1
8963
0.15
chr17_59299974_59300148 0.65 RP11-136H19.1

86736
0.08
chr1_40846013_40846164 0.64 SMAP2
small ArfGAP2
5768
0.19
chr4_40241072_40241223 0.64 RHOH
ras homolog family member H
39183
0.16
chr17_143001_143152 0.64 RP11-1260E13.1

28107
0.13
chr4_80979447_80979859 0.64 ANTXR2
anthrax toxin receptor 2
14064
0.28
chr1_160766044_160766224 0.63 LY9
lymphocyte antigen 9
157
0.95
chr5_54358310_54358461 0.63 ENSG00000240535
.
19713
0.12
chr3_57657337_57657512 0.63 DENND6A
DENN/MADD domain containing 6A
10871
0.15
chr9_129233663_129234100 0.62 ENSG00000252985
.
44709
0.13
chr2_54806956_54807355 0.62 SPTBN1
spectrin, beta, non-erythrocytic 1
21624
0.17
chr6_2222017_2222664 0.62 GMDS
GDP-mannose 4,6-dehydratase
23586
0.28
chr3_151916550_151916780 0.62 MBNL1
muscleblind-like splicing regulator 1
69164
0.11
chr3_111263833_111263984 0.61 CD96
CD96 molecule
2911
0.34
chr8_38219852_38220003 0.61 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
18412
0.12
chrX_77043283_77043438 0.61 ATRX
alpha thalassemia/mental retardation syndrome X-linked
1658
0.44
chr4_149576368_149576519 0.61 ENSG00000201846
.
97344
0.09
chr1_84609962_84610447 0.61 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
250
0.95
chr4_175442320_175442471 0.61 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
1089
0.66
chr1_145435026_145435343 0.60 TXNIP
thioredoxin interacting protein
3285
0.15
chr12_123131604_123131919 0.59 KNTC1
kinetochore associated 1
27172
0.15
chr16_71915132_71915582 0.59 RP11-498D10.3

819
0.43
chr1_111212990_111213454 0.59 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
4433
0.21
chr5_42993896_42994430 0.58 CTD-2035E11.3

24368
0.15
chr6_116786373_116786594 0.57 RP1-93H18.6

1628
0.26
chr18_77161034_77161555 0.57 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
902
0.67
chr3_18476686_18476837 0.57 SATB1
SATB homeobox 1
16
0.98
chr19_4915707_4915936 0.56 ARRDC5
arrestin domain containing 5
12942
0.12
chr19_48751567_48751718 0.56 CARD8
caspase recruitment domain family, member 8
1283
0.32
chr1_150976711_150976969 0.56 FAM63A
family with sequence similarity 63, member A
2121
0.14
chrX_19858890_19859041 0.56 SH3KBP1
SH3-domain kinase binding protein 1
41096
0.19
chr7_3156975_3157126 0.55 AC091801.1
LOC392621; Uncharacterized protein
40838
0.18
chr2_64368851_64369687 0.55 AC074289.1

1104
0.52
chr12_120978131_120978282 0.54 RNF10
ring finger protein 10
4977
0.12
chr11_86792508_86792683 0.54 TMEM135
transmembrane protein 135
43513
0.2
chr14_22967837_22967993 0.54 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
11744
0.1
chr10_20115112_20115263 0.54 PLXDC2
plexin domain containing 2
10019
0.21
chr1_186288985_186289136 0.54 ENSG00000202025
.
8000
0.18
chr8_82042923_82043106 0.53 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
18711
0.26
chr5_180336709_180336860 0.53 ENSG00000222852
.
54
0.72
chr1_226919798_226919959 0.53 ITPKB
inositol-trisphosphate 3-kinase B
5281
0.26
chr1_22087619_22087770 0.53 USP48
ubiquitin specific peptidase 48
20819
0.18
chr10_3825891_3827255 0.52 KLF6
Kruppel-like factor 6
812
0.68
chr11_34453040_34453191 0.52 CAT
catalase
7357
0.24
chr17_37932973_37933124 0.52 IKZF3
IKAROS family zinc finger 3 (Aiolos)
1430
0.33
chr1_14029095_14029323 0.52 PRDM2
PR domain containing 2, with ZNF domain
2141
0.32
chr1_81140230_81140381 0.52 ENSG00000266033
.
345132
0.01
chr6_90790037_90790282 0.52 ENSG00000222078
.
78934
0.1
chr13_41589998_41590808 0.52 ELF1
E74-like factor 1 (ets domain transcription factor)
3047
0.26
chr6_144631915_144632066 0.52 UTRN
utrophin
19025
0.22
chr1_160616059_160616370 0.51 SLAMF1
signaling lymphocytic activation molecule family member 1
597
0.7
chr12_15114929_15115219 0.51 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
412
0.82
chrX_24497884_24498038 0.51 PDK3
pyruvate dehydrogenase kinase, isozyme 3
14388
0.21
chr14_22749370_22749521 0.51 ENSG00000238634
.
138558
0.04
chr15_86246296_86246447 0.51 RP11-815J21.1

2031
0.21
chr14_71448816_71448967 0.51 PCNX
pecanex homolog (Drosophila)
30857
0.24
chr16_28152103_28152254 0.51 XPO6
exportin 6
28967
0.15
chr12_109252023_109252233 0.51 DAO
D-amino-acid oxidase
580
0.51
chr3_187903451_187903602 0.51 AC022498.1
Uncharacterized protein
7195
0.23
chr9_74980423_74981139 0.50 ZFAND5
zinc finger, AN1-type domain 5
618
0.81
chr2_43450614_43451227 0.50 ZFP36L2
ZFP36 ring finger protein-like 2
2828
0.31
chr6_138280285_138280436 0.50 RP11-356I2.4

90990
0.08
chr2_160426579_160426730 0.49 ENSG00000207117
.
33797
0.17
chr6_154570961_154571273 0.49 IPCEF1
interaction protein for cytohesin exchange factors 1
2301
0.45
chr15_40746159_40746352 0.49 RP11-64K12.9

583
0.57
chr7_72772148_72772660 0.49 ENSG00000206709
.
19201
0.13
chr1_160676943_160677601 0.49 CD48
CD48 molecule
4321
0.18
chr5_96268734_96268944 0.49 LNPEP
leucyl/cystinyl aminopeptidase
2329
0.27
chr8_82018570_82018849 0.49 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
5594
0.32
chr6_42743118_42743455 0.49 GLTSCR1L
GLTSCR1-like
6479
0.18
chr2_175475274_175475425 0.48 WIPF1
WAS/WASL interacting protein family, member 1
12410
0.19
chr19_17493496_17493698 0.48 PLVAP
plasmalemma vesicle associated protein
5438
0.09
chr2_47339184_47339335 0.48 C2orf61
chromosome 2 open reading frame 61
39175
0.14
chr11_48072944_48073095 0.48 AC103828.1

35612
0.15
chr3_151921407_151921835 0.47 MBNL1
muscleblind-like splicing regulator 1
64208
0.12
chr5_35853538_35853785 0.47 IL7R
interleukin 7 receptor
864
0.63
chr2_175462178_175462605 0.47 WIPF1
WAS/WASL interacting protein family, member 1
102
0.97
chr5_156997312_156997463 0.47 AC106801.1

4415
0.17
chr4_129026129_129026280 0.46 LARP1B
La ribonucleoprotein domain family, member 1B
27208
0.24
chr7_76009422_76009787 0.46 ZP3
zona pellucida glycoprotein 3 (sperm receptor)
17231
0.14
chr12_111868224_111868441 0.46 SH2B3
SH2B adaptor protein 3
4334
0.21
chr7_135656031_135656246 0.46 MTPN
myotrophin
5926
0.18
chr5_130602420_130602583 0.46 CDC42SE2
CDC42 small effector 2
2708
0.39
chr14_23009644_23009795 0.46 TRAJ15
T cell receptor alpha joining 15
11139
0.1
chr14_22590786_22590937 0.46 ENSG00000238634
.
20026
0.26
chr14_91854852_91855042 0.46 CCDC88C
coiled-coil domain containing 88C
28743
0.19
chr6_43021805_43021970 0.45 CUL7
cullin 7
204
0.85
chr16_56775385_56775536 0.45 NUP93
nucleoporin 93kDa
834
0.5
chr10_70818033_70818184 0.45 SRGN
serglycin
29766
0.15
chrX_44203045_44203476 0.45 EFHC2
EF-hand domain (C-terminal) containing 2
342
0.93
chr6_14955891_14956042 0.45 ENSG00000242989
.
157233
0.04
chr1_167059294_167059481 0.45 GPA33
glycoprotein A33 (transmembrane)
481
0.77
chr14_90083686_90083837 0.44 FOXN3
forkhead box N3
1713
0.27
chr2_143910122_143910273 0.44 RP11-190J23.1

19544
0.22
chr11_5713127_5713492 0.44 TRIM22
tripartite motif containing 22
1052
0.38
chrX_70415693_70415844 0.44 RP5-1091N2.9

2257
0.22
chr5_74346035_74346186 0.44 GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
19386
0.25
chr8_74904321_74904899 0.44 LY96
lymphocyte antigen 96
949
0.5
chr15_34626880_34627184 0.44 SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
2013
0.2
chr11_3880339_3880818 0.44 STIM1
stromal interaction molecule 1
3166
0.13
chr10_11210404_11210686 0.43 RP3-323N1.2

2794
0.27
chr1_207329382_207329533 0.43 C4BPA
complement component 4 binding protein, alpha
51806
0.12
chr2_231586204_231586355 0.43 CAB39
calcium binding protein 39
8016
0.22
chr3_141208110_141208261 0.43 RASA2
RAS p21 protein activator 2
2294
0.34
chr7_7287609_7287760 0.43 C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
13733
0.24
chr7_140075788_140076381 0.43 ENSG00000238868
.
618
0.63
chr5_169757977_169758251 0.43 KCNIP1
Kv channel interacting protein 1
22377
0.17
chr20_52226068_52226301 0.43 ZNF217
zinc finger protein 217
753
0.69
chr6_170862470_170862790 0.43 PSMB1
proteasome (prosome, macropain) subunit, beta type, 1
201
0.86
chr1_32739054_32739375 0.43 LCK
lymphocyte-specific protein tyrosine kinase
500
0.63
chr2_238166258_238166409 0.43 AC112715.2
Uncharacterized protein
599
0.83
chr5_43019046_43019566 0.43 CTD-2201E18.3

393
0.65
chr8_97324979_97325228 0.42 ENSG00000199732
.
3553
0.24
chr1_201140837_201140988 0.42 TMEM9
transmembrane protein 9
210
0.93
chr2_28614722_28614933 0.42 FOSL2
FOS-like antigen 2
842
0.55
chr17_68523399_68523550 0.42 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
357798
0.01
chr5_164888154_164888305 0.42 ENSG00000252794
.
148217
0.05
chr5_130602039_130602190 0.42 CDC42SE2
CDC42 small effector 2
2321
0.42
chr1_894870_895078 0.42 NOC2L
nucleolar complex associated 2 homolog (S. cerevisiae)
304
0.72
chr5_68903879_68904030 0.41 RP11-848G14.2

10186
0.18
chr19_12905241_12905397 0.41 CTD-2659N19.10

2318
0.1
chr2_136877707_136877858 0.41 CXCR4
chemokine (C-X-C motif) receptor 4
2047
0.45
chr2_172814531_172814813 0.41 HAT1
histone acetyltransferase 1
35697
0.16
chr1_27952458_27952609 0.41 FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
113
0.95
chr20_62266329_62266480 0.41 CTD-3184A7.4

7801
0.1
chr12_125412493_125412690 0.41 UBC
ubiquitin C
10677
0.16
chr5_39189307_39189510 0.41 FYB
FYN binding protein
13721
0.27
chr7_72436019_72436572 0.41 TRIM74
tripartite motif containing 74
1189
0.31
chr12_11803298_11803449 0.41 ETV6
ets variant 6
585
0.83
chr4_26398560_26398711 0.41 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
31707
0.23
chr4_6753373_6753524 0.41 KIAA0232
KIAA0232
30921
0.13
chr17_76776568_76776719 0.41 CYTH1
cytohesin 1
1711
0.35
chr1_28879171_28879359 0.40 TRNAU1AP
tRNA selenocysteine 1 associated protein 1
332
0.8
chr17_59300200_59300469 0.40 RP11-136H19.1

87009
0.08
chr14_61799597_61799891 0.40 PRKCH
protein kinase C, eta
6113
0.21
chr1_161035238_161035389 0.40 AL591806.1
Uncharacterized protein
342
0.73
chr3_30651643_30651972 0.40 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
3714
0.36
chr12_129336949_129337100 0.40 GLT1D1
glycosyltransferase 1 domain containing 1
1015
0.63
chr7_138790255_138790726 0.40 ZC3HAV1
zinc finger CCCH-type, antiviral 1
3610
0.26
chr11_123301934_123302187 0.40 AP000783.1
Uncharacterized protein
1002
0.62
chr22_45527492_45527643 0.40 NUP50
nucleoporin 50kDa
32155
0.16
chr2_231429426_231429577 0.40 AC010149.4

15147
0.18
chr2_145153762_145153913 0.40 ZEB2
zinc finger E-box binding homeobox 2
33756
0.21
chr10_14659560_14659768 0.40 FAM107B
family with sequence similarity 107, member B
5113
0.24
chr2_32817484_32817662 0.40 TTC27
tetratricopeptide repeat domain 27
35526
0.17
chr1_185308226_185308415 0.40 IVNS1ABP
influenza virus NS1A binding protein
21859
0.2
chr12_110517275_110517426 0.40 C12orf76
chromosome 12 open reading frame 76
5859
0.22
chr2_55236798_55237891 0.39 RTN4
reticulon 4
241
0.93
chr4_38857928_38858431 0.39 TLR6
toll-like receptor 6
258
0.48
chr12_869057_869208 0.39 WNK1
WNK lysine deficient protein kinase 1
6400
0.22
chr3_152098140_152098291 0.39 MBNL1
muscleblind-like splicing regulator 1
34632
0.17
chr14_98443402_98443682 0.39 C14orf64
chromosome 14 open reading frame 64
841
0.77
chr1_209930701_209930998 0.39 TRAF3IP3
TRAF3 interacting protein 3
994
0.46
chr2_87839408_87839559 0.39 RP11-1399P15.1

61930
0.14
chr20_3988099_3988250 0.39 RNF24
ring finger protein 24
7862
0.22
chr12_75875359_75875792 0.39 GLIPR1
GLI pathogenesis-related 1
591
0.74

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of FOXJ2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.3 0.7 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.3 0.8 GO:0030011 maintenance of cell polarity(GO:0030011)
0.2 0.7 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.2 0.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 1.6 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 0.6 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.3 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.3 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.5 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.7 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.4 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.6 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.7 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.5 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.1 GO:0045911 positive regulation of DNA recombination(GO:0045911)
0.1 0.3 GO:0006551 leucine metabolic process(GO:0006551)
0.1 0.3 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.2 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.2 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.4 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.2 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.8 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.1 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.5 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.2 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.4 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0000018 regulation of DNA recombination(GO:0000018)
0.0 0.0 GO:0044256 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.0 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.1 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.6 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.3 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.0 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0010823 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.1 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0002251 organ or tissue specific immune response(GO:0002251)
0.0 0.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.4 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.6 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.3 GO:0043266 regulation of potassium ion transport(GO:0043266)
0.0 0.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.0 GO:0002883 hypersensitivity(GO:0002524) regulation of acute inflammatory response to antigenic stimulus(GO:0002864) regulation of hypersensitivity(GO:0002883)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 1.1 GO:0016064 immunoglobulin mediated immune response(GO:0016064)
0.0 0.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.3 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.0 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.0 0.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.1 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.0 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0019079 viral genome replication(GO:0019079)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.0 GO:0046886 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.0 GO:0034443 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.8 GO:0097194 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.0 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.1 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.0 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.4 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.0 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.0 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.9 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.0 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.4 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.0 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.0 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.0 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.8 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0097191 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 1.0 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0017158 regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.0 GO:0019724 B cell mediated immunity(GO:0019724)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.0 0.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.0 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.1 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:2001233 regulation of release of cytochrome c from mitochondria(GO:0090199) regulation of apoptotic signaling pathway(GO:2001233)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 2.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.0 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.0 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 1.1 GO:0098562 cytoplasmic side of membrane(GO:0098562)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 1.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.8 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 0.7 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.3 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 1.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.6 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.6 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.0 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.0 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.0 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.0 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex