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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for FOXJ2

Z-value: 1.65

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Transcription factors associated with FOXJ2

Gene Symbol	Gene ID	Gene Info
FOXJ2 Ensembl NCBI GeneCards UniProt	ENSG00000065970.4	forkhead box J2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_8189890_8190041	FOXJ2	4009	0.186368	0.91	6.4e-04	Click!
chr12_8187512_8187701	FOXJ2	1650	0.323203	-0.79	1.2e-02	Click!
chr12_8179472_8180006	FOXJ2	5560	0.173547	0.56	1.1e-01	Click!
chr12_8186552_8186757	FOXJ2	698	0.640546	-0.51	1.6e-01	Click!
chr12_8191182_8191438	FOXJ2	5354	0.170227	-0.45	2.3e-01	Click!

Activity of the FOXJ2 motif across conditions

Conditions sorted by the z-value of the FOXJ2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_202127394_202127951	1.24	CASP8	caspase 8, apoptosis-related cysteine peptidase	993	0.56
chr1_198608588_198608957	1.15	PTPRC	protein tyrosine phosphatase, receptor type, C	480	0.86
chr20_47439188_47439680	1.09	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	4986	0.3
chr12_54891959_54892179	1.09	NCKAP1L	NCK-associated protein 1-like	499	0.73
chr9_95728150_95728303	1.05	FGD3	FYVE, RhoGEF and PH domain containing 3	1983	0.37
chr10_11212356_11212648	1.04	RP3-323N1.2		837	0.65
chr2_198172097_198172605	1.02	ANKRD44	ankyrin repeat domain 44	3160	0.2
chr13_31310422_31310683	1.00	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	907	0.71
chr1_114413652_114413958	0.98	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	515	0.69
chr8_27236494_27236808	0.98	PTK2B	protein tyrosine kinase 2 beta	1517	0.47
chr10_11217828_11218013	0.94	RP3-323N1.2		4581	0.25
chr17_43300272_43300459	0.93	CTD-2020K17.1		776	0.38
chr1_40526410_40526561	0.93	CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	19931	0.16
chr14_22631434_22631696	0.92	ENSG00000238634	.	20678	0.25
chr9_71783775_71784020	0.91	TJP2	tight junction protein 2	5184	0.29
chr1_185663060_185663272	0.89	HMCN1	hemicentin 1	40517	0.17
chr11_59320728_59320879	0.86	ENSG00000252893	.	5470	0.14
chr6_20174159_20174424	0.84	RP11-239H6.2		38027	0.18
chr17_29639732_29640055	0.82	EVI2B	ecotropic viral integration site 2B	1209	0.36
chr12_25206187_25206540	0.82	LRMP	lymphoid-restricted membrane protein	689	0.71
chr4_70625524_70625675	0.80	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	717	0.76
chr10_104926250_104926401	0.78	NT5C2	5'-nucleotidase, cytosolic II	8414	0.23
chr5_180231798_180232282	0.78	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	1117	0.47
chr8_103991507_103991658	0.78	ENSG00000265898	.	18434	0.14
chr13_41372571_41372761	0.77	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	5372	0.18
chrY_1605029_1605190	0.77	NA	NA	> 10⁶	NA
chr13_41592877_41593136	0.77	ELF1	E74-like factor 1 (ets domain transcription factor)	444	0.84
chr12_120974205_120974387	0.77	RNF10	ring finger protein 10	1067	0.34
chr6_31802179_31802624	0.76	C6orf48	chromosome 6 open reading frame 48	3	0.87
chrX_1655035_1655190	0.76	P2RY8	purinergic receptor P2Y, G-protein coupled, 8	888	0.64
chr15_86126252_86126683	0.73	RP11-815J21.2		3058	0.23
chrX_70331541_70331692	0.71	IL2RG	interleukin 2 receptor, gamma	135	0.92
chr6_143165995_143166218	0.71	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	7922	0.29
chr6_159465648_159465970	0.71	TAGAP	T-cell activation RhoGTPase activating protein	241	0.93
chr11_6767215_6767876	0.70	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2	22741	0.11
chr2_158295494_158296053	0.70	CYTIP	cytohesin 1 interacting protein	153	0.96
chr22_43011256_43011463	0.69	ENSG00000270022	.	109	0.79
chr21_36474794_36475157	0.68	RUNX1	runt-related transcription factor 1	53334	0.18
chr9_139433599_139433867	0.68	RP11-413M3.4		3600	0.12
chrX_78407252_78407403	0.67	GPR174	G protein-coupled receptor 174	19142	0.29
chr19_42061527_42061721	0.67	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	5738	0.18
chr2_204801338_204802214	0.67	ICOS	inducible T-cell co-stimulator	273	0.95
chr8_134070006_134070389	0.66	SLA	Src-like-adaptor	2406	0.36
chr11_82828119_82828301	0.66	PCF11	PCF11 cleavage and polyadenylation factor subunit	39820	0.12
chr5_96152602_96152931	0.65	ERAP1	endoplasmic reticulum aminopeptidase 1	8963	0.15
chr17_59299974_59300148	0.65	RP11-136H19.1		86736	0.08
chr1_40846013_40846164	0.64	SMAP2	small ArfGAP2	5768	0.19
chr4_40241072_40241223	0.64	RHOH	ras homolog family member H	39183	0.16
chr17_143001_143152	0.64	RP11-1260E13.1		28107	0.13
chr4_80979447_80979859	0.64	ANTXR2	anthrax toxin receptor 2	14064	0.28
chr1_160766044_160766224	0.63	LY9	lymphocyte antigen 9	157	0.95
chr5_54358310_54358461	0.63	ENSG00000240535	.	19713	0.12
chr3_57657337_57657512	0.63	DENND6A	DENN/MADD domain containing 6A	10871	0.15
chr9_129233663_129234100	0.62	ENSG00000252985	.	44709	0.13
chr2_54806956_54807355	0.62	SPTBN1	spectrin, beta, non-erythrocytic 1	21624	0.17
chr6_2222017_2222664	0.62	GMDS	GDP-mannose 4,6-dehydratase	23586	0.28
chr3_151916550_151916780	0.62	MBNL1	muscleblind-like splicing regulator 1	69164	0.11
chr3_111263833_111263984	0.61	CD96	CD96 molecule	2911	0.34
chr8_38219852_38220003	0.61	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	18412	0.12
chrX_77043283_77043438	0.61	ATRX	alpha thalassemia/mental retardation syndrome X-linked	1658	0.44
chr4_149576368_149576519	0.61	ENSG00000201846	.	97344	0.09
chr1_84609962_84610447	0.61	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	250	0.95
chr4_175442320_175442471	0.61	HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)	1089	0.66
chr1_145435026_145435343	0.60	TXNIP	thioredoxin interacting protein	3285	0.15
chr12_123131604_123131919	0.59	KNTC1	kinetochore associated 1	27172	0.15
chr16_71915132_71915582	0.59	RP11-498D10.3		819	0.43
chr1_111212990_111213454	0.59	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	4433	0.21
chr5_42993896_42994430	0.58	CTD-2035E11.3		24368	0.15
chr6_116786373_116786594	0.57	RP1-93H18.6		1628	0.26
chr18_77161034_77161555	0.57	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	902	0.67
chr3_18476686_18476837	0.57	SATB1	SATB homeobox 1	16	0.98
chr19_4915707_4915936	0.56	ARRDC5	arrestin domain containing 5	12942	0.12
chr19_48751567_48751718	0.56	CARD8	caspase recruitment domain family, member 8	1283	0.32
chr1_150976711_150976969	0.56	FAM63A	family with sequence similarity 63, member A	2121	0.14
chrX_19858890_19859041	0.56	SH3KBP1	SH3-domain kinase binding protein 1	41096	0.19
chr7_3156975_3157126	0.55	AC091801.1	LOC392621; Uncharacterized protein	40838	0.18
chr2_64368851_64369687	0.55	AC074289.1		1104	0.52
chr12_120978131_120978282	0.54	RNF10	ring finger protein 10	4977	0.12
chr11_86792508_86792683	0.54	TMEM135	transmembrane protein 135	43513	0.2
chr14_22967837_22967993	0.54	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	11744	0.1
chr10_20115112_20115263	0.54	PLXDC2	plexin domain containing 2	10019	0.21
chr1_186288985_186289136	0.54	ENSG00000202025	.	8000	0.18
chr8_82042923_82043106	0.53	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	18711	0.26
chr5_180336709_180336860	0.53	ENSG00000222852	.	54	0.72
chr1_226919798_226919959	0.53	ITPKB	inositol-trisphosphate 3-kinase B	5281	0.26
chr1_22087619_22087770	0.53	USP48	ubiquitin specific peptidase 48	20819	0.18
chr10_3825891_3827255	0.52	KLF6	Kruppel-like factor 6	812	0.68
chr11_34453040_34453191	0.52	CAT	catalase	7357	0.24
chr17_37932973_37933124	0.52	IKZF3	IKAROS family zinc finger 3 (Aiolos)	1430	0.33
chr1_14029095_14029323	0.52	PRDM2	PR domain containing 2, with ZNF domain	2141	0.32
chr1_81140230_81140381	0.52	ENSG00000266033	.	345132	0.01
chr6_90790037_90790282	0.52	ENSG00000222078	.	78934	0.1
chr13_41589998_41590808	0.52	ELF1	E74-like factor 1 (ets domain transcription factor)	3047	0.26
chr6_144631915_144632066	0.52	UTRN	utrophin	19025	0.22
chr1_160616059_160616370	0.51	SLAMF1	signaling lymphocytic activation molecule family member 1	597	0.7
chr12_15114929_15115219	0.51	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	412	0.82
chrX_24497884_24498038	0.51	PDK3	pyruvate dehydrogenase kinase, isozyme 3	14388	0.21
chr14_22749370_22749521	0.51	ENSG00000238634	.	138558	0.04
chr15_86246296_86246447	0.51	RP11-815J21.1		2031	0.21
chr14_71448816_71448967	0.51	PCNX	pecanex homolog (Drosophila)	30857	0.24
chr16_28152103_28152254	0.51	XPO6	exportin 6	28967	0.15
chr12_109252023_109252233	0.51	DAO	D-amino-acid oxidase	580	0.51
chr3_187903451_187903602	0.51	AC022498.1	Uncharacterized protein	7195	0.23
chr9_74980423_74981139	0.50	ZFAND5	zinc finger, AN1-type domain 5	618	0.81
chr2_43450614_43451227	0.50	ZFP36L2	ZFP36 ring finger protein-like 2	2828	0.31
chr6_138280285_138280436	0.50	RP11-356I2.4		90990	0.08
chr2_160426579_160426730	0.49	ENSG00000207117	.	33797	0.17
chr6_154570961_154571273	0.49	IPCEF1	interaction protein for cytohesin exchange factors 1	2301	0.45
chr15_40746159_40746352	0.49	RP11-64K12.9		583	0.57
chr7_72772148_72772660	0.49	ENSG00000206709	.	19201	0.13
chr1_160676943_160677601	0.49	CD48	CD48 molecule	4321	0.18
chr5_96268734_96268944	0.49	LNPEP	leucyl/cystinyl aminopeptidase	2329	0.27
chr8_82018570_82018849	0.49	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	5594	0.32
chr6_42743118_42743455	0.49	GLTSCR1L	GLTSCR1-like	6479	0.18
chr2_175475274_175475425	0.48	WIPF1	WAS/WASL interacting protein family, member 1	12410	0.19
chr19_17493496_17493698	0.48	PLVAP	plasmalemma vesicle associated protein	5438	0.09
chr2_47339184_47339335	0.48	C2orf61	chromosome 2 open reading frame 61	39175	0.14
chr11_48072944_48073095	0.48	AC103828.1		35612	0.15
chr3_151921407_151921835	0.47	MBNL1	muscleblind-like splicing regulator 1	64208	0.12
chr5_35853538_35853785	0.47	IL7R	interleukin 7 receptor	864	0.63
chr2_175462178_175462605	0.47	WIPF1	WAS/WASL interacting protein family, member 1	102	0.97
chr5_156997312_156997463	0.47	AC106801.1		4415	0.17
chr4_129026129_129026280	0.46	LARP1B	La ribonucleoprotein domain family, member 1B	27208	0.24
chr7_76009422_76009787	0.46	ZP3	zona pellucida glycoprotein 3 (sperm receptor)	17231	0.14
chr12_111868224_111868441	0.46	SH2B3	SH2B adaptor protein 3	4334	0.21
chr7_135656031_135656246	0.46	MTPN	myotrophin	5926	0.18
chr5_130602420_130602583	0.46	CDC42SE2	CDC42 small effector 2	2708	0.39
chr14_23009644_23009795	0.46	TRAJ15	T cell receptor alpha joining 15	11139	0.1
chr14_22590786_22590937	0.46	ENSG00000238634	.	20026	0.26
chr14_91854852_91855042	0.46	CCDC88C	coiled-coil domain containing 88C	28743	0.19
chr6_43021805_43021970	0.45	CUL7	cullin 7	204	0.85
chr16_56775385_56775536	0.45	NUP93	nucleoporin 93kDa	834	0.5
chr10_70818033_70818184	0.45	SRGN	serglycin	29766	0.15
chrX_44203045_44203476	0.45	EFHC2	EF-hand domain (C-terminal) containing 2	342	0.93
chr6_14955891_14956042	0.45	ENSG00000242989	.	157233	0.04
chr1_167059294_167059481	0.45	GPA33	glycoprotein A33 (transmembrane)	481	0.77
chr14_90083686_90083837	0.44	FOXN3	forkhead box N3	1713	0.27
chr2_143910122_143910273	0.44	RP11-190J23.1		19544	0.22
chr11_5713127_5713492	0.44	TRIM22	tripartite motif containing 22	1052	0.38
chrX_70415693_70415844	0.44	RP5-1091N2.9		2257	0.22
chr5_74346035_74346186	0.44	GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	19386	0.25
chr8_74904321_74904899	0.44	LY96	lymphocyte antigen 96	949	0.5
chr15_34626880_34627184	0.44	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6	2013	0.2
chr11_3880339_3880818	0.44	STIM1	stromal interaction molecule 1	3166	0.13
chr10_11210404_11210686	0.43	RP3-323N1.2		2794	0.27
chr1_207329382_207329533	0.43	C4BPA	complement component 4 binding protein, alpha	51806	0.12
chr2_231586204_231586355	0.43	CAB39	calcium binding protein 39	8016	0.22
chr3_141208110_141208261	0.43	RASA2	RAS p21 protein activator 2	2294	0.34
chr7_7287609_7287760	0.43	C1GALT1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1	13733	0.24
chr7_140075788_140076381	0.43	ENSG00000238868	.	618	0.63
chr5_169757977_169758251	0.43	KCNIP1	Kv channel interacting protein 1	22377	0.17
chr20_52226068_52226301	0.43	ZNF217	zinc finger protein 217	753	0.69
chr6_170862470_170862790	0.43	PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	201	0.86
chr1_32739054_32739375	0.43	LCK	lymphocyte-specific protein tyrosine kinase	500	0.63
chr2_238166258_238166409	0.43	AC112715.2	Uncharacterized protein	599	0.83
chr5_43019046_43019566	0.43	CTD-2201E18.3		393	0.65
chr8_97324979_97325228	0.42	ENSG00000199732	.	3553	0.24
chr1_201140837_201140988	0.42	TMEM9	transmembrane protein 9	210	0.93
chr2_28614722_28614933	0.42	FOSL2	FOS-like antigen 2	842	0.55
chr17_68523399_68523550	0.42	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2	357798	0.01
chr5_164888154_164888305	0.42	ENSG00000252794	.	148217	0.05
chr5_130602039_130602190	0.42	CDC42SE2	CDC42 small effector 2	2321	0.42
chr1_894870_895078	0.42	NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)	304	0.72
chr5_68903879_68904030	0.41	RP11-848G14.2		10186	0.18
chr19_12905241_12905397	0.41	CTD-2659N19.10		2318	0.1
chr2_136877707_136877858	0.41	CXCR4	chemokine (C-X-C motif) receptor 4	2047	0.45
chr2_172814531_172814813	0.41	HAT1	histone acetyltransferase 1	35697	0.16
chr1_27952458_27952609	0.41	FGR	feline Gardner-Rasheed sarcoma viral oncogene homolog	113	0.95
chr20_62266329_62266480	0.41	CTD-3184A7.4		7801	0.1
chr12_125412493_125412690	0.41	UBC	ubiquitin C	10677	0.16
chr5_39189307_39189510	0.41	FYB	FYN binding protein	13721	0.27
chr7_72436019_72436572	0.41	TRIM74	tripartite motif containing 74	1189	0.31
chr12_11803298_11803449	0.41	ETV6	ets variant 6	585	0.83
chr4_26398560_26398711	0.41	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	31707	0.23
chr4_6753373_6753524	0.41	KIAA0232	KIAA0232	30921	0.13
chr17_76776568_76776719	0.41	CYTH1	cytohesin 1	1711	0.35
chr1_28879171_28879359	0.40	TRNAU1AP	tRNA selenocysteine 1 associated protein 1	332	0.8
chr17_59300200_59300469	0.40	RP11-136H19.1		87009	0.08
chr14_61799597_61799891	0.40	PRKCH	protein kinase C, eta	6113	0.21
chr1_161035238_161035389	0.40	AL591806.1	Uncharacterized protein	342	0.73
chr3_30651643_30651972	0.40	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	3714	0.36
chr12_129336949_129337100	0.40	GLT1D1	glycosyltransferase 1 domain containing 1	1015	0.63
chr7_138790255_138790726	0.40	ZC3HAV1	zinc finger CCCH-type, antiviral 1	3610	0.26
chr11_123301934_123302187	0.40	AP000783.1	Uncharacterized protein	1002	0.62
chr22_45527492_45527643	0.40	NUP50	nucleoporin 50kDa	32155	0.16
chr2_231429426_231429577	0.40	AC010149.4		15147	0.18
chr2_145153762_145153913	0.40	ZEB2	zinc finger E-box binding homeobox 2	33756	0.21
chr10_14659560_14659768	0.40	FAM107B	family with sequence similarity 107, member B	5113	0.24
chr2_32817484_32817662	0.40	TTC27	tetratricopeptide repeat domain 27	35526	0.17
chr1_185308226_185308415	0.40	IVNS1ABP	influenza virus NS1A binding protein	21859	0.2
chr12_110517275_110517426	0.40	C12orf76	chromosome 12 open reading frame 76	5859	0.22
chr2_55236798_55237891	0.39	RTN4	reticulon 4	241	0.93
chr4_38857928_38858431	0.39	TLR6	toll-like receptor 6	258	0.48
chr12_869057_869208	0.39	WNK1	WNK lysine deficient protein kinase 1	6400	0.22
chr3_152098140_152098291	0.39	MBNL1	muscleblind-like splicing regulator 1	34632	0.17
chr14_98443402_98443682	0.39	C14orf64	chromosome 14 open reading frame 64	841	0.77
chr1_209930701_209930998	0.39	TRAF3IP3	TRAF3 interacting protein 3	994	0.46
chr2_87839408_87839559	0.39	RP11-1399P15.1		61930	0.14
chr20_3988099_3988250	0.39	RNF24	ring finger protein 24	7862	0.22
chr12_75875359_75875792	0.39	GLIPR1	GLI pathogenesis-related 1	591	0.74

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.5	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.3	0.7	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.3	0.8	GO:0030011	maintenance of cell polarity(GO:0030011)
0.2	0.7	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.2	0.7	GO:0019372	lipoxygenase pathway(GO:0019372)
0.2	1.6	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2	0.6	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.3	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.6	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.3	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1	0.3	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.3	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.5	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.3	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.7	GO:0015671	oxygen transport(GO:0015671)
0.1	0.3	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1	0.4	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	0.6	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.7	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.4	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.5	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1	0.2	GO:0009106	lipoate metabolic process(GO:0009106)
0.1	0.2	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.4	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.1	GO:0045911	positive regulation of DNA recombination(GO:0045911)
0.1	0.3	GO:0006551	leucine metabolic process(GO:0006551)
0.1	0.3	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.2	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.3	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.2	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.3	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.3	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.7	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.2	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.5	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.2	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.4	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.2	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.6	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.2	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.3	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.2	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.8	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.2	GO:0046902	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.3	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.5	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.2	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.2	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.2	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.6	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.4	GO:0030071	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:1903313	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.4	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.5	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0000018	regulation of DNA recombination(GO:0000018)
0.0	0.0	GO:0044256	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.6	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.3	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.0	GO:0032621	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0010823	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.1	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.0	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.4	GO:0006195	purine nucleotide catabolic process(GO:0006195)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.6	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.1	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.3	GO:0043266	regulation of potassium ion transport(GO:0043266)
0.0	0.2	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.2	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.0	GO:0002883	hypersensitivity(GO:0002524) regulation of acute inflammatory response to antigenic stimulus(GO:0002864) regulation of hypersensitivity(GO:0002883)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0050688	regulation of defense response to virus(GO:0050688)
0.0	1.1	GO:0016064	immunoglobulin mediated immune response(GO:0016064)
0.0	0.4	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.4	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.3	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0060253	negative regulation of glial cell proliferation(GO:0060253)
0.0	0.0	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.4	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.2	GO:0030890	positive regulation of B cell proliferation(GO:0030890)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0052572	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.1	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.0	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.3	GO:0019079	viral genome replication(GO:0019079)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.2	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.0	0.0	GO:0046886	positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.0	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0034443	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.0	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.8	GO:0097194	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.4	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.0	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.0	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0071501	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.2	GO:0000050	urea cycle(GO:0000050)
0.0	0.0	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.4	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.0	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.4	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.9	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.0	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.1	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.1	GO:0042026	protein refolding(GO:0042026)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.0	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.4	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0010259	multicellular organism aging(GO:0010259)
0.0	0.2	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.2	GO:0070206	protein trimerization(GO:0070206)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.4	GO:0015682	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.5	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.0	GO:0046831	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0	0.2	GO:0034968	histone lysine methylation(GO:0034968)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0016114	terpenoid biosynthetic process(GO:0016114)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.0	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0021683	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.8	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.0	0.1	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.0	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.0	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	1.0	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.2	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0019724	B cell mediated immunity(GO:0019724)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.0	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.0	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.1	GO:0009988	cell-cell recognition(GO:0009988)
0.0	0.0	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:2001233	regulation of release of cytochrome c from mitochondria(GO:0090199) regulation of apoptotic signaling pathway(GO:2001233)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.3	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	0.7	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0043159	acrosomal matrix(GO:0043159)
0.1	0.6	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.2	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	1.1	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	1.4	GO:0016605	PML body(GO:0016605)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.5	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.3	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	2.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.0	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.6	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.0	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.0	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	1.1	GO:0098562	cytoplasmic side of membrane(GO:0098562)
0.0	0.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.4	GO:0005884	actin filament(GO:0005884)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.6	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.6	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	1.4	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.3	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.6	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.9	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.8	GO:0000785	chromatin(GO:0000785)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0050544	arachidonic acid binding(GO:0050544)
0.2	0.7	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.2	0.5	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	0.8	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.2	0.6	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.9	GO:0005522	profilin binding(GO:0005522)
0.1	0.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.4	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.2	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.4	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.3	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	0.2	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.3	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.7	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.2	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	1.0	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.4	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	1.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.3	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.5	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.5	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0008252	nucleotidase activity(GO:0008252)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.6	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.5	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.2	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.6	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.1	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.5	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0	0.0	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.3	GO:0036459	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.4	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.2	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.0	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.0	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.4	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.2	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.0	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.3	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.2	GO:0019843	rRNA binding(GO:0019843)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	1.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	1.9	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	2.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	0.5	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.8	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.6	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	2.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	1.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.8	PID FOXO PATHWAY	FoxO family signaling
0.0	0.5	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.4	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.0	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.3	PID LKB1 PATHWAY	LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	1.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	0.9	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.7	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.2	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.5	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.6	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	1.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	1.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.7	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex

Results for FOXJ2

Z-value: 1.65

Motif logo

Transcription factors associated with FOXJ2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the FOXJ2 motif across conditions

Conditions sorted by the z-value of the FOXJ2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: