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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for FOXN1

Z-value: 3.05

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Transcription factors associated with FOXN1

Gene Symbol	Gene ID	Gene Info
FOXN1 Ensembl NCBI GeneCards UniProt	ENSG00000109101.3	forkhead box N1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_26859594_26859745	FOXN1	8710	0.087481	-0.36	3.4e-01	Click!
chr17_26832875_26833026	FOXN1	311	0.807577	-0.25	5.2e-01	Click!
chr17_26834751_26834902	FOXN1	1548	0.235607	0.18	6.3e-01	Click!
chr17_26833380_26833531	FOXN1	177	0.901455	-0.09	8.1e-01	Click!

Activity of the FOXN1 motif across conditions

Conditions sorted by the z-value of the FOXN1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr20_62257766_62257982	1.50	GMEB2	glucocorticoid modulatory element binding protein 2	520	0.48
chr8_24771817_24771968	0.98	GS1-72M22.1		338	0.64
chr10_5488617_5489358	0.92	NET1	neuroepithelial cell transforming 1	413	0.83
chrX_134166329_134166771	0.90	FAM127A	family with sequence similarity 127, member A	217	0.92
chr18_712290_712543	0.87	ENOSF1	enolase superfamily member 1	128	0.93
chr8_145024226_145024570	0.86	PLEC	plectin	646	0.55
chr15_37390103_37390360	0.79	MEIS2	Meis homeobox 2	272	0.88
chr5_77944256_77944475	0.77	LHFPL2	lipoma HMGIC fusion partner-like 2	283	0.95
chr9_98279774_98279925	0.77	PTCH1	patched 1	510	0.75
chr16_29823160_29823365	0.77	AC009133.14		44	0.52
chr19_13262272_13262447	0.72	IER2	immediate early response 2	430	0.63
chr11_66512330_66512648	0.71	C11orf80	chromosome 11 open reading frame 80	126	0.94
chr10_118734084_118734359	0.70	KIAA1598	KIAA1598	30655	0.21
chr11_66045277_66045517	0.68	CNIH2	cornichon family AMPA receptor auxiliary protein 2	264	0.57
chr3_180320366_180320663	0.68	TTC14	tetratricopeptide repeat domain 14	164	0.95
chr17_66097735_66097982	0.68	LINC00674	long intergenic non-protein coding RNA 674	191	0.95
chr14_60632044_60632195	0.68	DHRS7	dehydrogenase/reductase (SDR family) member 7	92	0.98
chr9_34458041_34458192	0.66	FAM219A	family with sequence similarity 219, member A	434	0.58
chr20_62257208_62257699	0.65	GMEB2	glucocorticoid modulatory element binding protein 2	941	0.32
chr5_1004458_1005031	0.65	ENSG00000221244	.	442	0.76
chr1_98569638_98569861	0.65	ENSG00000225206	.	58022	0.17
chr6_42879136_42879323	0.65	PTCRA	pre T-cell antigen receptor alpha	4498	0.12
chr2_190305327_190305991	0.65	WDR75	WD repeat domain 75	500	0.87
chr6_32552056_32552278	0.65	HLA-DRB1	major histocompatibility complex, class II, DR beta 1	5458	0.15
chr18_3012840_3013077	0.64	LPIN2	lipin 2	355	0.86
chr9_99775769_99776027	0.63	HIATL2	hippocampus abundant transcript-like 2	36	0.98
chr15_52471956_52472147	0.63	GNB5	guanine nucleotide binding protein (G protein), beta 5	33	0.97
chr16_56715848_56716189	0.63	MT1X	metallothionein 1X	318	0.76
chr2_132250084_132250258	0.62	MZT2A	mitotic spindle organizing protein 2A	176	0.92
chr6_166756394_166756643	0.62	SFT2D1	SFT2 domain containing 1	439	0.83
chr12_81331086_81331493	0.62	LIN7A	lin-7 homolog A (C. elegans)	194	0.63
chr17_6915961_6916214	0.61	RNASEK	ribonuclease, RNase K	122	0.73
chr7_100304309_100304512	0.61	POP7	processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)	451	0.69
chr16_12070231_12070442	0.61	RP11-166B2.1	Putative NPIP-like protein LOC729978	155	0.62
chrX_134185751_134186149	0.61	FAM127B	family with sequence similarity 127, member B	255	0.91
chr4_178363635_178364106	0.60	AGA	aspartylglucosaminidase	213	0.92
chr7_4764745_4765032	0.60	FOXK1	forkhead box K1	15602	0.18
chr6_16128869_16129101	0.59	MYLIP	myosin regulatory light chain interacting protein	371	0.86
chr6_135501734_135502104	0.59	MYB	v-myb avian myeloblastosis viral oncogene homolog	534	0.78
chr9_74979276_74979450	0.59	ZFAND5	zinc finger, AN1-type domain 5	179	0.97
chr6_83777413_83777651	0.58	DOPEY1	dopey family member 1	142	0.95
chr1_218458674_218459446	0.58	RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)	431	0.88
chr19_41111211_41111409	0.58	ENSG00000266164	.	1645	0.28
chr3_39447834_39448018	0.58	RPSA	ribosomal protein SA	254	0.86
chr2_112896439_112896616	0.58	FBLN7	fibulin 7	367	0.91
chr14_97499318_97499622	0.58	VRK1	vaccinia related kinase 1	157104	0.04
chr6_18122528_18122892	0.57	NHLRC1	NHL repeat containing E3 ubiquitin protein ligase 1	141	0.96
chr9_140498838_140498989	0.57	ARRDC1	arrestin domain containing 1	1193	0.33
chr14_23450829_23451172	0.57	AJUBA	ajuba LIM protein	205	0.66
chr5_88184954_88185150	0.57	MEF2C-AS1	MEF2C antisense RNA 1	73	0.98
chr14_88458720_88459036	0.57	GALC	galactosylceramidase	304	0.88
chr6_32605503_32605654	0.56	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	381	0.81
chr11_9335504_9335681	0.55	TMEM41B	transmembrane protein 41B	585	0.76
chr14_63671686_63671939	0.55	RHOJ	ras homolog family member J	235	0.95
chr8_41997978_41998266	0.55	RP11-589C21.5		12159	0.17
chr9_99687451_99687602	0.55	NUTM2G	NUT family member 2G	3066	0.31
chr9_179160_179373	0.55	CBWD1	COBW domain containing 1	194	0.94
chr3_141378876_141379089	0.55	RNF7	ring finger protein 7	78064	0.09
chr7_1237832_1237995	0.55	UNCX	UNC homeobox	34630	0.12
chr13_45152333_45152558	0.54	TSC22D1	TSC22 domain family, member 1	1162	0.61
chr6_3157103_3157543	0.54	TUBB2A	tubulin, beta 2A class IIa	437	0.77
chr6_128841609_128841760	0.54	PTPRK	protein tyrosine phosphatase, receptor type, K	44	0.97
chr3_87276490_87276813	0.54	CHMP2B	charged multivesicular body protein 2B	199	0.92
chr3_39448232_39448433	0.53	RPSA	ribosomal protein SA	106	0.94
chr3_47021157_47021360	0.53	NBEAL2	neurobeachin-like 2	85	0.67
chr12_121837288_121837671	0.53	ANAPC5	anaphase promoting complex subunit 5	220	0.66
chr7_124404783_124404934	0.53	GPR37	G protein-coupled receptor 37 (endothelin receptor type B-like)	823	0.74
chr22_32057126_32057277	0.53	PISD	phosphatidylserine decarboxylase	965	0.58
chr2_85640695_85641186	0.53	CAPG	capping protein (actin filament), gelsolin-like	222	0.85
chr11_118977640_118977897	0.53	C2CD2L	C2CD2-like	325	0.69
chr5_322963_323164	0.53	AHRR	aryl-hydrocarbon receptor repressor	308	0.89
chr7_106301045_106301255	0.53	CCDC71L	coiled-coil domain containing 71-like	292	0.93
chr19_510720_510899	0.52	AC005775.2		2996	0.12
chr6_2764985_2765181	0.52	WRNIP1	Werner helicase interacting protein 1	565	0.77
chr10_135209173_135209324	0.52	MTG1	mitochondrial ribosome-associated GTPase 1	1570	0.2
chr1_204380536_204380863	0.52	PPP1R15B	protein phosphatase 1, regulatory subunit 15B	220	0.93
chr16_69372986_69373204	0.52	NIP7	NIP7, nucleolar pre-rRNA processing protein	238	0.53
chr11_95522797_95522967	0.52	FAM76B	family with sequence similarity 76, member B	73	0.74
chr17_80376697_80377584	0.52	HEXDC	hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing	525	0.41
chr17_31270819_31270970	0.52	TMEM98	transmembrane protein 98	12842	0.19
chr14_89771641_89771801	0.52	RP11-356K23.1		44908	0.14
chr20_4741487_4741694	0.51	PRNT	prion protein (testis specific)	20276	0.18
chr13_26624895_26625081	0.51	SHISA2	shisa family member 2	181	0.97
chr8_11725136_11725560	0.51	CTSB	cathepsin B	146	0.95
chr9_35162020_35162251	0.51	UNC13B	unc-13 homolog B (C. elegans)	34	0.97
chr12_56473896_56474122	0.51	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3	58	0.93
chr4_102267764_102268012	0.51	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme	65	0.95
chr9_69262672_69262918	0.51	CBWD6	COBW domain containing 6	202	0.94
chr8_33330355_33330583	0.51	FUT10	fucosyltransferase 10 (alpha (1,3) fucosyltransferase)	168	0.94
chr19_10764196_10764505	0.50	ILF3	interleukin enhancer binding factor 3, 90kDa	587	0.62
chr2_61764720_61765137	0.50	XPO1	exportin 1 (CRM1 homolog, yeast)	153	0.96
chr2_242577050_242577249	0.50	ATG4B	autophagy related 4B, cysteine peptidase	5	0.8
chr17_38210419_38210617	0.50	MED24	mediator complex subunit 24	140	0.93
chr17_14207744_14207895	0.50	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	3419	0.33
chr16_1429359_1429577	0.50	ENSG00000265529	.	44	0.66
chr15_83735644_83735965	0.50	BTBD1	BTB (POZ) domain containing 1	99	0.73
chr6_111135805_111136044	0.50	CDK19	cyclin-dependent kinase 19	375	0.86
chr8_30515908_30516093	0.50	GTF2E2	general transcription factor IIE, polypeptide 2, beta 34kDa	232	0.92
chr12_54071089_54071258	0.50	ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)	9	0.97
chr1_36621953_36622250	0.49	MAP7D1	MAP7 domain containing 1	298	0.87
chr2_114195012_114195248	0.49	CBWD2	COBW domain containing 2	138	0.95
chr11_17098625_17099136	0.49	RPS13	ribosomal protein S13	314	0.76
chr1_86969615_86969766	0.49	CLCA1	chloride channel accessory 1	35164	0.16
chr9_70856505_70856767	0.49	CBWD3	COBW domain containing 3	239	0.92
chr4_110354814_110355122	0.48	SEC24B	SEC24 family member B	1	0.5
chr12_104457931_104458153	0.48	GLT8D2	glycosyltransferase 8 domain containing 2	81	0.66
chr5_9546839_9547056	0.48	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	760	0.6
chr20_61584687_61584941	0.48	SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9	416	0.8
chr5_71405528_71405679	0.48	MAP1B	microtubule-associated protein 1B	2290	0.41
chr17_78194256_78194578	0.48	SLC26A11	solute carrier family 26 (anion exchanger), member 11	149	0.59
chr5_31531844_31532215	0.48	DROSHA	drosha, ribonuclease type III	139	0.75
chr6_38607788_38608212	0.48	BTBD9	BTB (POZ) domain containing 9	76	0.98
chr2_20251239_20251427	0.48	LAPTM4A	lysosomal protein transmembrane 4 alpha	456	0.53
chr2_98611816_98612023	0.48	TMEM131	transmembrane protein 131	435	0.89
chr3_123602332_123603013	0.47	MYLK	myosin light chain kinase	477	0.85
chr8_11057742_11057983	0.47	XKR6	XK, Kell blood group complex subunit-related family, member 6	986	0.53
chr13_103333360_103333511	0.47	METTL21C	methyltransferase like 21C	13419	0.16
chr6_3054491_3054642	0.47	RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	14092	0.12
chr8_23386540_23386755	0.47	SLC25A37	solute carrier family 25 (mitochondrial iron transporter), member 37	74	0.97
chr11_12696098_12696447	0.47	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	108	0.98
chr9_27529480_27529683	0.47	MOB3B	MOB kinase activator 3B	198	0.95
chr16_65157967_65158128	0.46	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	1779	0.55
chr7_130132965_130133179	0.46	MEST	mesoderm specific transcript	759	0.48
chr15_68871678_68872325	0.46	CORO2B	coronin, actin binding protein, 2B	428	0.9
chr8_22549992_22550198	0.46	EGR3	early growth response 3	168	0.92
chr16_19079207_19079451	0.46	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	18	0.82
chr12_133345723_133345874	0.45	ANKLE2	ankyrin repeat and LEM domain containing 2	7324	0.16
chr14_19649786_19649937	0.45	ENSG00000212612	.	85076	0.09
chr2_177042560_177043156	0.45	HOXD-AS1	HOXD cluster antisense RNA 1	5	0.95
chr8_90995843_90996298	0.45	NBN	nibrin	395	0.87
chrX_135579787_135580822	0.45	HTATSF1	HIV-1 Tat specific factor 1	634	0.65
chr18_29672927_29673084	0.45	RNF138	ring finger protein 138, E3 ubiquitin protein ligase	340	0.7
chr1_7831350_7831659	0.45	VAMP3	vesicle-associated membrane protein 3	175	0.93
chr17_79886368_79886629	0.45	MAFG-AS1	MAFG antisense RNA 1 (head to head)	221	0.73
chr7_100770539_100770851	0.45	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	316	0.81
chr11_110301192_110301536	0.45	FDX1	ferredoxin 1	757	0.79
chr8_121823531_121824050	0.44	SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)	593	0.5
chr1_32281411_32281574	0.44	SPOCD1	SPOC domain containing 1	88	0.97
chr7_82791356_82791849	0.44	PCLO	piccolo presynaptic cytomatrix protein	644	0.84
chr7_28429293_28429606	0.44	CREB5	cAMP responsive element binding protein 5	19557	0.28
chr5_83016736_83016887	0.44	HAPLN1	hyaluronan and proteoglycan link protein 1	179	0.95
chr14_95973302_95973453	0.44	RP11-1070N10.3	Uncharacterized protein	9096	0.15
chr5_14870333_14870900	0.44	ANKH	ANKH inorganic pyrophosphate transport regulator	1271	0.52
chr21_28515725_28515968	0.44	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	177014	0.03
chr17_34842467_34842676	0.44	ZNHIT3	zinc finger, HIT-type containing 3	1	0.96
chr14_96857563_96858081	0.44	AK7	adenylate kinase 7	626	0.65
chr1_19536525_19536703	0.44	UBR4	ubiquitin protein ligase E3 component n-recognin 4	132	0.77
chr17_48133106_48133356	0.44	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	108	0.95
chr16_69373250_69373458	0.43	NIP7	NIP7, nucleolar pre-rRNA processing protein	21	0.5
chr6_13711072_13711306	0.43	RANBP9	RAN binding protein 9	607	0.75
chr7_5821069_5821360	0.43	RNF216	ring finger protein 216	37	0.98
chr18_11269079_11269368	0.43	PIEZO2	piezo-type mechanosensitive ion channel component 2	120636	0.06
chr4_1283578_1283845	0.43	MAEA	macrophage erythroblast attacher	28	0.97
chr1_160231777_160232156	0.43	DCAF8	DDB1 and CUL4 associated factor 8	231	0.67
chr15_29033796_29033964	0.43	RP11-578F21.10		132	0.96
chr16_89314305_89314531	0.43	RP11-46C24.6		19318	0.1
chr22_45706486_45706804	0.43	FAM118A	family with sequence similarity 118, member A	640	0.72
chr4_108852198_108852659	0.42	CYP2U1	cytochrome P450, family 2, subfamily U, polypeptide 1	97	0.92
chr1_231664492_231664694	0.42	TSNAX	translin-associated factor X	192	0.62
chr9_66553620_66553804	0.42	ENSG00000202474	.	95450	0.09
chr4_140375006_140375182	0.42	RP11-83A24.2		15	0.63
chr15_45004214_45004438	0.42	B2M	beta-2-microglobulin	611	0.66
chr5_110559928_110560116	0.42	CAMK4	calcium/calmodulin-dependent protein kinase IV	238	0.95
chr5_118324382_118324613	0.42	DTWD2	DTW domain containing 2	257	0.92
chr9_70490242_70490494	0.42	CBWD5	COBW domain containing 5	122	0.98
chr8_94929112_94929401	0.42	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1	23	0.95
chr18_9136201_9136544	0.42	RP11-143J12.2		117	0.54
chr2_114513406_114513771	0.42	SLC35F5	solute carrier family 35, member F5	609	0.76
chr22_31795635_31796389	0.41	DRG1	developmentally regulated GTP binding protein 1	503	0.7
chr9_139582480_139582663	0.41	AGPAT2	1-acylglycerol-3-phosphate O-acyltransferase 2	696	0.45
chrX_73833904_73834302	0.41	RLIM	ring finger protein, LIM domain interacting	349	0.91
chr10_65028344_65028625	0.41	JMJD1C	jumonji domain containing 1C	342	0.93
chr15_66798440_66798603	0.41	ZWILCH	zwilch kinetochore protein	883	0.28
chr1_9600826_9600977	0.41	SLC25A33	solute carrier family 25 (pyrimidine nucleotide carrier), member 33	1360	0.48
chr3_161089453_161089887	0.41	SPTSSB	serine palmitoyltransferase, small subunit B	381	0.92
chr8_79428088_79428454	0.41	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	103	0.98
chr10_49647799_49647950	0.41	ARHGAP22	Rho GTPase activating protein 22	11796	0.23
chr11_74303961_74304177	0.40	POLD3	polymerase (DNA-directed), delta 3, accessory subunit	380	0.88
chr2_225811426_225811868	0.40	DOCK10	dedicator of cytokinesis 10	135	0.98
chr17_3627280_3627662	0.40	GSG2	germ cell associated 2 (haspin)	260	0.84
chr1_226373449_226374067	0.40	ACBD3	acyl-CoA binding domain containing 3	673	0.7
chr1_77684704_77685054	0.40	PIGK	phosphatidylinositol glycan anchor biosynthesis, class K	232	0.95
chr6_138188427_138188618	0.40	TNFAIP3	tumor necrosis factor, alpha-induced protein 3	59	0.81
chr20_55966718_55966885	0.40	RBM38	RNA binding motif protein 38	317	0.81
chr15_23158544_23158713	0.40	RP11-26F2.1		12631	0.16
chr22_23527376_23527533	0.40	BCR	breakpoint cluster region	4902	0.16
chr4_6565771_6565922	0.40	PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	519	0.8
chr12_12715567_12715848	0.40	DUSP16	dual specificity phosphatase 16	390	0.89
chr11_75947236_75947447	0.40	WNT11	wingless-type MMTV integration site family, member 11	25561	0.17
chr15_25936345_25936497	0.40	ATP10A	ATPase, class V, type 10A	3551	0.27
chr22_21622272_21622426	0.40	GGT2	gamma-glutamyltransferase 2	40423	0.13
chr11_72929013_72929272	0.40	P2RY2	purinergic receptor P2Y, G-protein coupled, 2	201	0.91
chr12_122015832_122015983	0.40	KDM2B	lysine (K)-specific demethylase 2B	1642	0.38
chr16_4426884_4427106	0.40	VASN	vasorin	5146	0.13
chr12_53719733_53719917	0.39	AAAS	achalasia, adrenocortical insufficiency, alacrimia	1283	0.29
chr11_65667660_65668040	0.39	FOSL1	FOS-like antigen 1	40	0.94
chr10_90750353_90750504	0.39	FAS	Fas cell surface death receptor	14	0.92
chr3_49841121_49841386	0.39	FAM212A	family with sequence similarity 212, member A	566	0.54
chr5_71615645_71615979	0.39	MRPS27	mitochondrial ribosomal protein S27	237	0.65
chrX_54070514_54070754	0.39	PHF8	PHD finger protein 8	27	0.98

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXN1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.2	0.7	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.2	0.6	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.2	0.2	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.2	0.7	GO:0061042	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.2	0.8	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2	0.5	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	0.6	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.1	0.4	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	1.0	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.7	GO:0032202	telomere assembly(GO:0032202)
0.1	0.7	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.1	0.6	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.8	GO:0000012	single strand break repair(GO:0000012)
0.1	0.4	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.4	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.5	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.5	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.1	0.5	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.1	0.6	GO:0060406	positive regulation of penile erection(GO:0060406)
0.1	0.1	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.1	0.6	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.8	GO:0000090	mitotic anaphase(GO:0000090)
0.1	0.3	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.2	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.7	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	0.7	GO:0010939	regulation of necrotic cell death(GO:0010939)
0.1	0.3	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.3	GO:0071436	sodium ion export(GO:0071436)
0.1	0.3	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	0.4	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.1	0.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.3	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.4	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.1	0.3	GO:0031223	auditory behavior(GO:0031223)
0.1	0.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.3	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.1	0.3	GO:0005997	xylulose metabolic process(GO:0005997)
0.1	0.2	GO:0035067	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.4	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1	0.4	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.3	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.1	0.4	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1	0.2	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.2	GO:0060751	branch elongation involved in mammary gland duct branching(GO:0060751)
0.1	0.4	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.4	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.1	0.2	GO:0060157	urinary bladder development(GO:0060157)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.3	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.2	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.1	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.7	GO:0006983	ER overload response(GO:0006983)
0.1	0.2	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.4	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.1	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.1	0.2	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	0.1	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1	0.4	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.1	GO:2000573	positive regulation of DNA biosynthetic process(GO:2000573)
0.1	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.1	0.2	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.1	GO:1900121	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.1	0.2	GO:0019605	butyrate metabolic process(GO:0019605)
0.1	0.2	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	0.3	GO:0000239	pachytene(GO:0000239)
0.1	0.2	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1	0.3	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.7	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.1	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1	0.3	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.8	GO:0014037	Schwann cell differentiation(GO:0014037)
0.1	0.2	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.2	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.1	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1	0.4	GO:0075713	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.1	0.8	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1	0.2	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.1	0.3	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.1	0.1	GO:1903519	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.3	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.2	GO:0051608	histamine transport(GO:0051608)
0.1	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.5	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1	0.6	GO:0007020	microtubule nucleation(GO:0007020)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.1	0.2	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.1	0.1	GO:0007144	female meiosis I(GO:0007144)
0.1	1.0	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	0.2	GO:0031297	replication fork processing(GO:0031297)
0.1	0.3	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.2	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.7	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.1	0.1	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.6	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1	0.4	GO:0006013	mannose metabolic process(GO:0006013)
0.1	0.2	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.2	GO:0002468	dendritic cell antigen processing and presentation(GO:0002468) regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1	0.2	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.2	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.1	0.3	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.3	GO:0032042	mitochondrial DNA metabolic process(GO:0032042)
0.0	0.2	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.0	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.5	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.2	GO:0046831	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.2	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.7	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.6	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.2	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0009452	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.1	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.3	GO:0016236	macroautophagy(GO:0016236)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.0	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.2	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.5	GO:0010165	response to X-ray(GO:0010165)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.4	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0042663	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.3	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0010800	regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.5	GO:0016180	snRNA processing(GO:0016180)
0.0	0.7	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.4	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.3	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.3	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0043084	penile erection(GO:0043084)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.5	GO:0046697	decidualization(GO:0046697)
0.0	0.2	GO:0051775	response to redox state(GO:0051775)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.4	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.3	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.5	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.4	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.6	GO:0046794	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.6	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.2	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.5	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.1	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.6	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.4	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0070932	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.3	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.2	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.2	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.1	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0	0.3	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:0072665	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.5	GO:0032648	regulation of interferon-beta production(GO:0032648)
0.0	0.2	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.2	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.3	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	2.1	GO:0006354	DNA-templated transcription, elongation(GO:0006354)
0.0	0.3	GO:0002209	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.1	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.4	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.1	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.1	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0034502	protein localization to chromosome(GO:0034502)
0.0	0.0	GO:0052556	positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.5	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.4	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0032402	melanosome transport(GO:0032402)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.3	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0060968	regulation of gene silencing(GO:0060968)
0.0	0.1	GO:0090151	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.0	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.3	GO:0008272	sulfate transport(GO:0008272)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.3	GO:0043526	obsolete neuroprotection(GO:0043526)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.4	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.1	GO:0018202	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:1902224	ketone body metabolic process(GO:1902224)
0.0	0.1	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.0	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.2	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.0	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0016114	terpenoid biosynthetic process(GO:0016114)
0.0	0.0	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.6	GO:0045727	positive regulation of translation(GO:0045727)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.3	GO:0008542	visual learning(GO:0008542)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.2	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.7	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.4	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.5	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	1.5	GO:0016197	endosomal transport(GO:0016197)
0.0	0.3	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.1	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.0	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.1	GO:0006907	pinocytosis(GO:0006907)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.0	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.0	0.1	GO:1903727	positive regulation of phospholipid metabolic process(GO:1903727)
0.0	0.2	GO:0008088	axo-dendritic transport(GO:0008088)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.2	GO:0072350	citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.2	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.9	GO:0051168	nuclear export(GO:0051168)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.6	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	1.2	GO:0006415	translational termination(GO:0006415)
0.0	0.7	GO:0006119	oxidative phosphorylation(GO:0006119)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.2	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.0	GO:0051709	regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	1.0	GO:0008033	tRNA processing(GO:0008033)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.3	GO:0006885	regulation of pH(GO:0006885)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0033363	secretory granule organization(GO:0033363)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.7	GO:0009063	cellular amino acid catabolic process(GO:0009063)
0.0	0.1	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.8	GO:0006826	iron ion transport(GO:0006826)
0.0	0.3	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.0	1.3	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.0	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.0	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.5	GO:0009408	response to heat(GO:0009408)
0.0	0.1	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.3	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0090662	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.0	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.0	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	0.1	GO:0060479	lung cell differentiation(GO:0060479)
0.0	0.2	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.3	GO:0000077	DNA damage checkpoint(GO:0000077)
0.0	0.1	GO:0051153	regulation of striated muscle cell differentiation(GO:0051153)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:1902808	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0006414	translational elongation(GO:0006414)
0.0	1.2	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.3	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	1.6	GO:0006470	protein dephosphorylation(GO:0006470)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0046514	ceramide catabolic process(GO:0046514)
0.0	0.2	GO:0043928	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.0	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.0	0.0	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0	0.0	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.0	0.0	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.4	GO:0000910	cytokinesis(GO:0000910)
0.0	3.0	GO:0016567	protein ubiquitination(GO:0016567)
0.0	0.2	GO:0006284	base-excision repair(GO:0006284)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.0	GO:2000134	negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.0	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.0	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.6	GO:0000279	M phase(GO:0000279)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0007398	ectoderm development(GO:0007398)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0032069	regulation of nuclease activity(GO:0032069)
0.0	0.2	GO:0009066	aspartate family amino acid metabolic process(GO:0009066)
0.0	0.0	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:1902668	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0	0.4	GO:0010827	regulation of glucose transport(GO:0010827)
0.0	0.0	GO:0043486	histone exchange(GO:0043486)
0.0	0.0	GO:0014065	phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0	0.0	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.0	GO:0001504	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.0	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.0	GO:0016199	axon midline choice point recognition(GO:0016199)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	1.0	GO:0030686	90S preribosome(GO:0030686)
0.1	0.5	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.3	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	0.4	GO:0016600	flotillin complex(GO:0016600)
0.1	0.3	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.3	GO:0008537	proteasome activator complex(GO:0008537)
0.1	0.6	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	0.8	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1	0.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.2	GO:0045298	tubulin complex(GO:0045298)
0.1	0.2	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	0.5	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.9	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	0.3	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	0.5	GO:0035253	ciliary rootlet(GO:0035253)
0.1	0.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	0.8	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.6	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1	2.2	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1	0.4	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1	0.2	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.2	GO:0031933	telomeric heterochromatin(GO:0031933)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0032059	bleb(GO:0032059)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.7	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.5	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.3	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.3	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.3	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.5	GO:0032039	integrator complex(GO:0032039)
0.0	0.3	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.3	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.3	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.4	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.7	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.8	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152) anaphase-promoting complex(GO:0005680)
0.0	1.2	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.2	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	1.3	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.4	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	1.2	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.4	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.4	GO:0071203	WASH complex(GO:0071203)
0.0	0.6	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	1.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	1.1	GO:0015030	Cajal body(GO:0015030)
0.0	0.3	GO:0030914	STAGA complex(GO:0030914)
0.0	0.5	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.5	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.3	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	1.4	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.4	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0030992	intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.5	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.0	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.6	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	1.1	GO:0042383	sarcolemma(GO:0042383)
0.0	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0022624	proteasome accessory complex(GO:0022624)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.7	GO:0022626	cytosolic ribosome(GO:0022626)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.4	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0055037	recycling endosome(GO:0055037)
0.0	0.9	GO:0030496	midbody(GO:0030496)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	3.9	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.9	GO:0005802	trans-Golgi network(GO:0005802)
0.0	4.0	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	1.2	GO:0005643	nuclear pore(GO:0005643)
0.0	0.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.3	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.8	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0032155	cell division site(GO:0032153) cell division site part(GO:0032155)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.0	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.3	GO:0044438	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	1.3	GO:0019717	obsolete synaptosome(GO:0019717)
0.0	0.6	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	1.1	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	1.5	GO:0005769	early endosome(GO:0005769)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	1.3	GO:0010008	endosome membrane(GO:0010008)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0044391	ribosomal subunit(GO:0044391)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.4	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.6	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.3	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0030120	vesicle coat(GO:0030120)
0.0	0.0	GO:0032838	cell projection cytoplasm(GO:0032838)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.3	GO:0000922	spindle pole(GO:0000922)
0.0	0.0	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.0	GO:0030894	replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0	0.1	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.3	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.2	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.6	GO:0005840	ribosome(GO:0005840)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.1	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.4	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	6.4	GO:0005739	mitochondrion(GO:0005739)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.3	GO:0001669	acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2	0.6	GO:0005113	patched binding(GO:0005113)
0.1	0.4	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	0.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.4	GO:0045545	syndecan binding(GO:0045545)
0.1	0.4	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.4	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.5	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.4	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.3	GO:0031177	phosphopantetheine binding(GO:0031177)
0.1	0.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.4	GO:0005534	galactose binding(GO:0005534)
0.1	0.8	GO:0005522	profilin binding(GO:0005522)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.3	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1	0.5	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.3	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.4	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.3	GO:0051425	PTB domain binding(GO:0051425)
0.1	1.0	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.3	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.3	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.3	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.1	0.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.1	0.2	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.1	0.7	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	0.3	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1	0.5	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.2	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.5	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.5	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	1.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	0.3	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.2	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.3	GO:0034452	dynactin binding(GO:0034452)
0.1	0.3	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.2	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.3	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.3	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.5	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	0.2	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	0.2	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.1	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.1	0.2	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	1.1	GO:0043621	protein self-association(GO:0043621)
0.1	0.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	0.5	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.2	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.3	GO:0016530	metallochaperone activity(GO:0016530)
0.1	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.4	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.1	0.2	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	2.3	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.5	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.3	GO:0015929	hexosaminidase activity(GO:0015929)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.2	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.8	GO:0043022	ribosome binding(GO:0043022)
0.0	0.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.3	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.3	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.2	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.4	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	1.0	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.2	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.7	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.4	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.9	GO:0034061	DNA polymerase activity(GO:0034061)
0.0	0.2	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	1.3	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	1.0	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.3	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.4	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.3	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.4	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	1.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.6	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.4	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	2.2	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.5	GO:1990782	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.2	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	1.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.5	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.3	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.2	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	5.5	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.3	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.5	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.8	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	2.3	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	1.0	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	1.7	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.5	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.1	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.5	GO:0002020	protease binding(GO:0002020)
0.0	0.6	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.8	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.2	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.0	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	2.4	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.0	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.2	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	1.9	GO:0016874	ligase activity(GO:0016874)
0.0	0.6	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.3	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.3	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0043531	ADP binding(GO:0043531)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.0	GO:0032135	DNA insertion or deletion binding(GO:0032135)
0.0	0.0	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.2	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.0	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	1.4	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0070815	procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.0	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.3	GO:0008137	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.0	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.0	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0008483	transaminase activity(GO:0008483)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.6	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	0.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	1.5	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.2	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	1.1	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.8	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.7	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.8	PID FOXO PATHWAY	FoxO family signaling
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.9	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	1.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	1.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.3	PID ATM PATHWAY	ATM pathway
0.0	0.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.2	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.6	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.5	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.5	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.1	PID ATR PATHWAY	ATR signaling pathway
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.3	PID P73PATHWAY	p73 transcription factor network
0.0	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.3	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	0.3	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	0.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	0.7	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.2	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.1	0.6	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	0.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	0.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.4	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.5	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.8	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.4	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	1.0	REACTOME HIV LIFE CYCLE	Genes involved in HIV Life Cycle
0.0	1.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.4	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.1	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.8	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	1.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.7	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.3	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.8	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	4.0	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.4	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	1.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.0	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	1.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)

Results for FOXN1

Z-value: 3.05

Motif logo

Transcription factors associated with FOXN1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the FOXN1 motif across conditions

Conditions sorted by the z-value of the FOXN1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXN1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: