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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for FOXO3_FOXD2

Z-value: 1.32

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Transcription factors associated with FOXO3_FOXD2

Gene Symbol	Gene ID	Gene Info
FOXO3 Ensembl NCBI GeneCards UniProt	ENSG00000118689.10	forkhead box O3
FOXD2 Ensembl NCBI GeneCards UniProt	ENSG00000186564.5	forkhead box D2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_47910279_47910719	FOXD2	8810	0.155967	0.53	1.5e-01	Click!
chr1_47903418_47903665	FOXD2	1852	0.271818	0.51	1.6e-01	Click!
chr1_47903753_47903904	FOXD2	2139	0.245073	0.50	1.7e-01	Click!
chr1_47901909_47902060	FOXD2	295	0.850629	-0.46	2.2e-01	Click!
chr1_47904279_47904442	FOXD2	2671	0.213702	0.28	4.6e-01	Click!
chr6_108909192_108909395	FOXO3	27224	0.244696	-0.86	2.6e-03	Click!
chr6_108879841_108880669	FOXO3	783	0.767603	0.86	3.0e-03	Click!
chr6_108956949_108957100	FOXO3	20525	0.266785	0.78	1.3e-02	Click!
chr6_108930431_108930582	FOXO3	47043	0.182465	-0.77	1.6e-02	Click!
chr6_108910495_108910681	FOXO3	28519	0.240636	-0.72	2.7e-02	Click!

Activity of the FOXO3_FOXD2 motif across conditions

Conditions sorted by the z-value of the FOXO3_FOXD2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_150264558_150265605	1.78	GIMAP4	GTPase, IMAP family member 4	557	0.78
chr4_89884993_89885181	1.13	FAM13A	family with sequence similarity 13, member A	65964	0.13
chr10_22944496_22944670	1.10	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	58454	0.15
chr1_161154335_161154531	1.06	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	7146	0.07
chr1_209930701_209930998	0.95	TRAF3IP3	TRAF3 interacting protein 3	994	0.46
chr19_17861983_17862176	0.93	FCHO1	FCH domain only 1	207	0.91
chr1_111417492_111418003	0.92	CD53	CD53 molecule	1971	0.34
chr6_159465648_159465970	0.92	TAGAP	T-cell activation RhoGTPase activating protein	241	0.93
chr3_151917198_151917573	0.90	MBNL1	muscleblind-like splicing regulator 1	68444	0.12
chrX_70329371_70329522	0.89	IL2RG	interleukin 2 receptor, gamma	328	0.79
chr5_39073301_39073622	0.85	RICTOR	RPTOR independent companion of MTOR, complex 2	1030	0.63
chr16_30484007_30484505	0.84	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	184	0.81
chr3_16328270_16328443	0.83	OXNAD1	oxidoreductase NAD-binding domain containing 1	17608	0.16
chr5_39218193_39218351	0.82	FYB	FYN binding protein	1393	0.56
chr7_157145359_157145611	0.82	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	12970	0.24
chr5_39201497_39202174	0.80	FYB	FYN binding protein	1294	0.59
chr1_169679248_169679951	0.80	SELL	selectin L	1240	0.48
chr22_24824729_24824978	0.80	ADORA2A	adenosine A2a receptor	1323	0.44
chr5_118606701_118606876	0.77	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2339	0.29
chr9_274295_274630	0.77	DOCK8	dedicator of cytokinesis 8	1392	0.34
chr13_41554167_41554365	0.77	ELF1	E74-like factor 1 (ets domain transcription factor)	2152	0.33
chr11_6767215_6767876	0.76	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2	22741	0.11
chr11_3009712_3009890	0.75	NAP1L4	nucleosome assembly protein 1-like 4	588	0.57
chr11_75063940_75064091	0.75	ARRB1	arrestin, beta 1	1142	0.41
chr10_3514525_3515428	0.74	RP11-184A2.3		278283	0.01
chr22_40859575_40859744	0.74	MKL1	megakaryoblastic leukemia (translocation) 1	221	0.93
chr17_29636179_29636457	0.74	EVI2B	ecotropic viral integration site 2B	4784	0.15
chr15_34626880_34627184	0.74	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6	2013	0.2
chr1_198612556_198613143	0.72	PTPRC	protein tyrosine phosphatase, receptor type, C	4557	0.28
chr5_130602039_130602190	0.72	CDC42SE2	CDC42 small effector 2	2321	0.42
chr4_40202894_40203061	0.71	RHOH	ras homolog family member H	1013	0.59
chr11_6766181_6766335	0.71	GVINP1	GTPase, very large interferon inducible pseudogene 1	23147	0.11
chr19_42946806_42946957	0.71	CXCL17	chemokine (C-X-C motif) ligand 17	319	0.82
chr15_81594027_81594306	0.70	IL16	interleukin 16	2409	0.29
chr19_16255232_16255383	0.69	HSH2D	hematopoietic SH2 domain containing	761	0.53
chr3_151911560_151911983	0.69	MBNL1	muscleblind-like splicing regulator 1	74058	0.11
chr15_80260314_80260502	0.69	BCL2A1	BCL2-related protein A1	3103	0.24
chr3_142663096_142663442	0.67	RP11-372E1.4		6187	0.16
chr2_161995820_161996335	0.67	TANK	TRAF family member-associated NFKB activator	2611	0.33
chr20_52226068_52226301	0.67	ZNF217	zinc finger protein 217	753	0.69
chr12_110517460_110517751	0.67	C12orf76	chromosome 12 open reading frame 76	6114	0.22
chr13_74806186_74806399	0.67	ENSG00000206617	.	57059	0.16
chr22_40323366_40323609	0.67	GRAP2	GRB2-related adaptor protein 2	846	0.6
chr12_109028220_109028371	0.67	SELPLG	selectin P ligand	560	0.6
chr1_207996298_207996642	0.66	ENSG00000203709	.	20602	0.22
chr14_102228850_102229271	0.66	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	205	0.93
chr6_108143523_108143878	0.66	SCML4	sex comb on midleg-like 4 (Drosophila)	1816	0.46
chr6_10528716_10529334	0.65	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	436	0.83
chr2_204571383_204571580	0.64	CD28	CD28 molecule	65	0.98
chr10_129846333_129846652	0.64	PTPRE	protein tyrosine phosphatase, receptor type, E	658	0.81
chr17_66433856_66434617	0.64	WIPI1	WD repeat domain, phosphoinositide interacting 1	4524	0.23
chr9_92111480_92111784	0.63	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	715	0.59
chrX_24498316_24498580	0.62	PDK3	pyruvate dehydrogenase kinase, isozyme 3	14875	0.2
chr16_68033325_68033555	0.62	DPEP2	dipeptidase 2	19	0.94
chr3_185826921_185827162	0.62	ETV5	ets variant 5	140	0.97
chr1_174934321_174935265	0.62	RABGAP1L	RAB GTPase activating protein 1-like	888	0.52
chr11_102192518_102192994	0.60	BIRC3	baculoviral IAP repeat containing 3	3196	0.22
chr17_46505734_46505885	0.60	SKAP1	src kinase associated phosphoprotein 1	1743	0.29
chr7_134832355_134832754	0.60	TMEM140	transmembrane protein 140	270	0.58
chr13_49136021_49136172	0.60	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	28727	0.23
chr19_13906051_13906257	0.60	ZSWIM4	zinc finger, SWIM-type containing 4	120	0.9
chr22_37310592_37310811	0.60	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	1026	0.44
chr12_122239467_122240363	0.59	RHOF	ras homolog family member F (in filopodia)	919	0.49
chr16_11677800_11677980	0.59	LITAF	lipopolysaccharide-induced TNF factor	2339	0.3
chr2_197032904_197033284	0.58	STK17B	serine/threonine kinase 17b	2630	0.28
chr10_22622036_22622322	0.58	BMI1	BMI1 polycomb ring finger oncogene	6731	0.15
chr22_47010573_47010731	0.58	GRAMD4	GRAM domain containing 4	5647	0.26
chr3_50643497_50643669	0.58	CISH	cytokine inducible SH2-containing protein	5620	0.15
chr2_204801338_204802214	0.58	ICOS	inducible T-cell co-stimulator	273	0.95
chr1_186291918_186292069	0.58	ENSG00000202025	.	10933	0.17
chr1_239881158_239881438	0.58	ENSG00000233355	.	1068	0.49
chr14_22696848_22696999	0.58	ENSG00000238634	.	86036	0.09
chr3_128838049_128838200	0.58	RAB43	RAB43, member RAS oncogene family	2500	0.18
chr12_739347_739498	0.58	RP11-218M22.1		635	0.67
chr8_126960676_126960849	0.57	ENSG00000206695	.	47567	0.2
chr8_133770966_133771357	0.57	TMEM71	transmembrane protein 71	1633	0.38
chr1_160547631_160547822	0.57	CD84	CD84 molecule	1537	0.33
chr3_3214293_3214763	0.56	CRBN	cereblon	6830	0.19
chr6_26404189_26404392	0.56	BTN3A1	butyrophilin, subfamily 3, member A1	1767	0.21
chr17_37933203_37933446	0.56	IKZF3	IKAROS family zinc finger 3 (Aiolos)	1154	0.4
chr2_20776643_20776868	0.56	HS1BP3-IT1	HS1BP3 intronic transcript 1 (non-protein coding)	15553	0.21
chrX_19858890_19859041	0.56	SH3KBP1	SH3-domain kinase binding protein 1	41096	0.19
chr8_117664591_117664742	0.56	EIF3H	eukaryotic translation initiation factor 3, subunit H	103357	0.07
chr17_76776568_76776719	0.56	CYTH1	cytohesin 1	1711	0.35
chr8_38215592_38215743	0.56	RP11-513D5.2		22168	0.11
chr20_37503630_37503889	0.56	ENSG00000240474	.	2346	0.31
chr3_58319217_58319933	0.55	PXK	PX domain containing serine/threonine kinase	542	0.78
chr10_6585169_6585583	0.55	PRKCQ	protein kinase C, theta	36825	0.22
chr17_75103441_75103592	0.55	ENSG00000234912	.	18127	0.18
chr14_50830018_50830334	0.55	CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	22329	0.16
chr18_60874185_60874445	0.55	ENSG00000238988	.	12417	0.23
chr7_134832844_134833492	0.55	AC083862.1	Uncharacterized protein	252	0.58
chr6_159074554_159074705	0.55	SYTL3	synaptotagmin-like 3	3583	0.22
chr1_212769581_212769895	0.55	ATF3	activating transcription factor 3	12274	0.15
chr7_37448490_37448719	0.54	ENSG00000200113	.	10627	0.2
chr6_152505186_152505339	0.54	SYNE1	spectrin repeat containing, nuclear envelope 1	15763	0.29
chr1_181003153_181003921	0.53	MR1	major histocompatibility complex, class I-related	398	0.84
chr4_71860383_71860569	0.53	DCK	deoxycytidine kinase	1121	0.6
chr3_111266223_111266431	0.53	CD96	CD96 molecule	5330	0.28
chr4_154456967_154457118	0.53	KIAA0922	KIAA0922	20006	0.24
chr5_137548291_137548968	0.53	CDC23	cell division cycle 23	383	0.81
chr6_150954132_150954283	0.53	RP11-136K14.2		8394	0.22
chr14_21580100_21580251	0.53	ENSG00000200102	.	1729	0.21
chr1_111215452_111215765	0.53	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	2047	0.31
chr2_87799012_87799242	0.53	RP11-1399P15.1		21574	0.26
chr1_25656822_25656973	0.52	TMEM50A	transmembrane protein 50A	7511	0.13
chr3_16927344_16927610	0.52	PLCL2	phospholipase C-like 2	1025	0.65
chr3_108205436_108205587	0.52	MYH15	myosin, heavy chain 15	42658	0.16
chr1_226251298_226251924	0.52	H3F3A	H3 histone, family 3A	67	0.97
chr12_92531544_92532018	0.52	C12orf79	chromosome 12 open reading frame 79	984	0.53
chr7_44665248_44665399	0.52	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	1262	0.46
chr4_84035760_84036001	0.52	PLAC8	placenta-specific 8	9	0.98
chr17_65241820_65242054	0.52	HELZ	helicase with zinc finger	168	0.89
chr10_17726067_17726351	0.52	ENSG00000251959	.	5022	0.18
chr6_20174159_20174424	0.52	RP11-239H6.2		38027	0.18
chr5_96268734_96268944	0.51	LNPEP	leucyl/cystinyl aminopeptidase	2329	0.27
chr17_37932472_37932886	0.51	IKZF3	IKAROS family zinc finger 3 (Aiolos)	1799	0.27
chr6_25035340_25035594	0.51	ENSG00000244618	.	3957	0.21
chr9_88953252_88953465	0.51	ZCCHC6	zinc finger, CCHC domain containing 6	4680	0.26
chr17_56564699_56564919	0.51	HSF5	heat shock transcription factor family member 5	936	0.46
chrX_135578358_135578906	0.51	HTATSF1	HIV-1 Tat specific factor 1	606	0.66
chr10_4173141_4173857	0.51	KLF6	Kruppel-like factor 6	346026	0.01
chr6_5997225_5997376	0.51	NRN1	neuritin 1	9900	0.25
chr19_15441735_15441977	0.51	BRD4	bromodomain containing 4	861	0.58
chr13_99953472_99953749	0.50	GPR183	G protein-coupled receptor 183	6049	0.22
chr2_158298330_158298802	0.50	ENSG00000216054	.	504	0.79
chr6_143163152_143163303	0.50	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	5043	0.32
chr14_102289544_102289975	0.50	CTD-2017C7.2		13101	0.14
chr7_1086655_1086891	0.50	GPR146	G protein-coupled receptor 146	2561	0.15
chr17_28033493_28033909	0.50	RP11-82O19.1		54420	0.07
chr2_71644611_71645120	0.50	ZNF638	zinc finger protein 638	10496	0.21
chr5_130867858_130868086	0.50	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	32	0.99
chr3_30672898_30673049	0.49	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	24880	0.25
chr7_50350563_50350714	0.49	IKZF1	IKAROS family zinc finger 1 (Ikaros)	2320	0.42
chr10_116282270_116282421	0.49	ABLIM1	actin binding LIM protein 1	4249	0.31
chr8_67592554_67592762	0.49	C8orf44	chromosome 8 open reading frame 44	4204	0.17
chr16_11676480_11676631	0.49	LITAF	lipopolysaccharide-induced TNF factor	3674	0.24
chr9_140021893_140022077	0.48	ENSG00000238824	.	3925	0.07
chr2_201987013_201987300	0.48	CFLAR	CASP8 and FADD-like apoptosis regulator	44	0.96
chr14_102990020_102990171	0.48	ANKRD9	ankyrin repeat domain 9	13959	0.15
chrX_70415693_70415844	0.48	RP5-1091N2.9		2257	0.22
chr12_4937651_4937802	0.48	RP3-377H17.2		10395	0.2
chr18_46477576_46477867	0.48	SMAD7	SMAD family member 7	640	0.78
chr4_15659797_15659948	0.48	FBXL5	F-box and leucine-rich repeat protein 5	1615	0.4
chr10_46075820_46076565	0.48	MARCH8	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase	13747	0.25
chr6_152506299_152506551	0.48	SYNE1	spectrin repeat containing, nuclear envelope 1	16926	0.28
chr22_38793751_38794050	0.48	CSNK1E	casein kinase 1, epsilon	627	0.62
chrX_41190531_41191099	0.47	DDX3X	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	1836	0.31
chr1_158982562_158982777	0.47	IFI16	interferon, gamma-inducible protein 16	1802	0.37
chr12_53765254_53765569	0.47	SP1	Sp1 transcription factor	8549	0.12
chrX_47863575_47863949	0.47	SPACA5	sperm acrosome associated 5	28	0.86
chr17_29146967_29147192	0.47	CRLF3	cytokine receptor-like factor 3	4610	0.14
chr1_66806954_66807105	0.47	PDE4B	phosphodiesterase 4B, cAMP-specific	9157	0.31
chr1_198608588_198608957	0.47	PTPRC	protein tyrosine phosphatase, receptor type, C	480	0.86
chr8_82054077_82054228	0.47	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	29849	0.23
chr10_21914636_21914787	0.47	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	25972	0.17
chr1_8536501_8536652	0.47	ENSG00000221083	.	35402	0.16
chr19_16482667_16482930	0.47	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	10034	0.15
chr18_77283391_77284187	0.46	AC018445.1	Uncharacterized protein	7732	0.29
chr15_93352280_93352431	0.46	CTD-2313J17.1		558	0.5
chr11_46140422_46140573	0.46	PHF21A	PHD finger protein 21A	841	0.64
chr9_123684302_123684484	0.46	TRAF1	TNF receptor-associated factor 1	6654	0.22
chr1_198638370_198638521	0.46	RP11-553K8.5		2255	0.38
chr8_9938305_9938456	0.46	ENSG00000221320	.	7051	0.21
chr11_65149415_65150138	0.46	SLC25A45	solute carrier family 25, member 45	68	0.95
chr5_172352379_172352530	0.46	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	19391	0.15
chr15_70727721_70727872	0.46	ENSG00000200216	.	242221	0.02
chr7_38272697_38272848	0.45	STARD3NL	STARD3 N-terminal like	54775	0.17
chr12_58233713_58233864	0.45	RP11-620J15.1		2913	0.13
chr10_6622430_6623103	0.45	PRKCQ	protein kinase C, theta	503	0.89
chr12_120974205_120974387	0.45	RNF10	ring finger protein 10	1067	0.34
chr2_197024603_197024962	0.45	STK17B	serine/threonine kinase 17b	3411	0.25
chrX_13773669_13773820	0.45	OFD1	oral-facial-digital syndrome 1	20880	0.16
chr4_199492_199643	0.45	ZNF876P	zinc finger protein 876, pseudogene	12872	0.19
chr4_73951905_73952308	0.45	COX18	COX18 cytochrome C oxidase assembly factor	16648	0.24
chr12_12867727_12867916	0.45	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	2237	0.23
chr1_116293768_116293919	0.45	CASQ2	calsequestrin 2 (cardiac muscle)	17492	0.24
chr12_11804572_11805680	0.45	ETV6	ets variant 6	2338	0.4
chr7_74188079_74188230	0.44	NCF1	neutrophil cytosolic factor 1	155	0.96
chr7_72634383_72634534	0.44	NCF1B	neutrophil cytosolic factor 1B pseudogene	153	0.95
chr7_74587895_74588046	0.44	GTF2IRD2B	GTF2I repeat domain containing 2B	31066	0.2
chr6_12010262_12011396	0.44	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	1404	0.51
chr5_43019046_43019566	0.44	CTD-2201E18.3		393	0.65
chr3_134204282_134204486	0.44	CEP63	centrosomal protein 63kDa	201	0.75
chrX_78205532_78205824	0.44	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	4760	0.35
chr18_60823743_60823894	0.44	RP11-299P2.1		5265	0.26
chr1_26453661_26453812	0.44	PDIK1L	PDLIM1 interacting kinase 1 like	15396	0.1
chr12_66585568_66585719	0.44	IRAK3	interleukin-1 receptor-associated kinase 3	2606	0.24
chr10_120937254_120937443	0.43	PRDX3	peroxiredoxin 3	997	0.45
chr6_24926129_24926280	0.43	FAM65B	family with sequence similarity 65, member B	9984	0.23
chr6_24934559_24934719	0.43	FAM65B	family with sequence similarity 65, member B	1549	0.46
chr2_227703538_227703689	0.43	RHBDD1	rhomboid domain containing 1	1349	0.49
chr6_106545216_106545824	0.43	PRDM1	PR domain containing 1, with ZNF domain	961	0.58
chr17_75437754_75438017	0.43	ENSG00000200651	.	306	0.87
chr5_140997567_140997853	0.43	AC008781.7		271	0.75
chr1_179846681_179846874	0.43	TOR1AIP2	torsin A interacting protein 2	157	0.94
chr4_40242815_40242966	0.43	RHOH	ras homolog family member H	40926	0.15
chr13_95923472_95923623	0.43	ABCC4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	30042	0.17
chrX_135204007_135204158	0.43	ENSG00000239080	.	12497	0.21
chr6_2222723_2222882	0.43	GMDS	GDP-mannose 4,6-dehydratase	23124	0.28

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO3_FOXD2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	0.4	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.2	0.5	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	0.5	GO:0006667	sphinganine metabolic process(GO:0006667)
0.2	0.5	GO:0046548	retinal rod cell development(GO:0046548)
0.1	0.4	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	1.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.1	0.4	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	0.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.4	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.4	GO:0014055	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1	0.4	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.1	0.5	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	0.5	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.4	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.5	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.1	0.3	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.5	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.2	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.5	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.1	0.5	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.6	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.3	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.2	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1	0.6	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	1.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.2	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	1.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1	0.3	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	1.3	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.1	1.0	GO:0042554	superoxide anion generation(GO:0042554)
0.1	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.3	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.1	0.2	GO:2000188	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.2	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.4	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.3	GO:0006534	cysteine metabolic process(GO:0006534)
0.1	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.3	GO:0051642	centrosome localization(GO:0051642)
0.1	0.4	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.1	0.2	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1	0.4	GO:0003254	regulation of membrane depolarization(GO:0003254) regulation of mitochondrial depolarization(GO:0051900)
0.1	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.1	GO:0090200	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.1	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.1	0.2	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.3	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.1	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1	0.7	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.1	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	0.5	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.1	0.3	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.4	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.1	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.1	0.4	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.1	0.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1	0.3	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	1.1	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.1	0.2	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.7	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.1	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.5	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.3	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.2	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.4	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.3	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.2	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.7	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.2	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0061756	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.2	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0021591	ventricular system development(GO:0021591)
0.0	0.2	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.2	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.1	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.2	GO:0031297	replication fork processing(GO:0031297)
0.0	0.2	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.6	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.2	GO:0051446	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.0	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.0	0.2	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.2	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.5	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.2	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.5	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.0	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0	0.3	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.2	GO:0075713	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.6	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.2	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.5	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0	0.2	GO:0006983	ER overload response(GO:0006983)
0.0	0.3	GO:0051322	anaphase(GO:0051322)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	1.9	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.1	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.3	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.4	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	1.1	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.0	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.6	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.0	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.3	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.5	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:1903313	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.2	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.2	GO:0007099	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.2	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.0	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.2	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.4	GO:0051225	spindle assembly(GO:0051225)
0.0	2.0	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.2	GO:0009650	UV protection(GO:0009650)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:2000053	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0009180	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.5	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.3	GO:0030149	sphingolipid catabolic process(GO:0030149)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.1	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0021683	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.4	GO:0016236	macroautophagy(GO:0016236)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.2	GO:0001881	receptor recycling(GO:0001881)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.4	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0050687	negative regulation of response to biotic stimulus(GO:0002832) negative regulation of defense response to virus(GO:0050687)
0.0	0.0	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.2	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.3	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.3	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.9	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.0	0.0	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	1.5	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122)
0.0	0.1	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.0	GO:0014009	glial cell proliferation(GO:0014009)
0.0	0.0	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	1.7	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	1.8	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.2	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.2	GO:0006672	ceramide metabolic process(GO:0006672)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.5	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.3	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.3	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.4	GO:0006829	zinc II ion transport(GO:0006829)
0.0	1.9	GO:0043087	regulation of GTPase activity(GO:0043087)
0.0	0.0	GO:0051000	positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.2	GO:0051297	centrosome organization(GO:0051297)
0.0	0.1	GO:0034227	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.2	GO:0006801	superoxide metabolic process(GO:0006801)
0.0	0.4	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0	0.1	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0098781	rRNA transcription(GO:0009303) ncRNA transcription(GO:0098781)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.3	GO:0006354	DNA-templated transcription, elongation(GO:0006354)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.3	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.2	GO:0019674	NAD metabolic process(GO:0019674)
0.0	0.3	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.0	GO:0007506	gonadal mesoderm development(GO:0007506)
0.0	0.4	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	0.0	GO:0031033	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0	0.2	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.4	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.0	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.2	GO:0034968	histone lysine methylation(GO:0034968)
0.0	0.0	GO:0097205	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.0	0.0	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.5	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.2	GO:0042752	regulation of circadian rhythm(GO:0042752)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.1	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.0	0.0	GO:0002016	regulation of blood volume by renin-angiotensin(GO:0002016)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:2000351	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.0	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0021697	cerebellar cortex formation(GO:0021697)
0.0	0.1	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.2	GO:0007051	spindle organization(GO:0007051)
0.0	0.2	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.0	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.2	GO:0051651	maintenance of location in cell(GO:0051651)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0006555	methionine metabolic process(GO:0006555)
0.0	1.6	GO:0006457	protein folding(GO:0006457)
0.0	0.0	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.0	GO:0021604	rhombomere 4 development(GO:0021570) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.1	GO:0009268	response to pH(GO:0009268)
0.0	0.0	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.5	GO:0006839	mitochondrial transport(GO:0006839)
0.0	0.0	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	2.1	GO:0008380	RNA splicing(GO:0008380)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.2	0.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.4	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.9	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	1.2	GO:0001772	immunological synapse(GO:0001772)
0.1	0.6	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1	0.5	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	1.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.2	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.4	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.1	0.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.3	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1	0.2	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.3	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	0.4	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.1	0.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.4	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.3	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.2	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	1.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.3	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.4	GO:0008278	cohesin complex(GO:0008278)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	1.0	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.5	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.2	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.3	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.2	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	1.4	GO:0000786	nucleosome(GO:0000786)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.7	GO:0016592	mediator complex(GO:0016592)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	2.4	GO:0016607	nuclear speck(GO:0016607)
0.0	0.4	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.6	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.5	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	2.7	GO:0005769	early endosome(GO:0005769)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.7	GO:0030118	clathrin coat(GO:0030118)
0.0	1.0	GO:0016605	PML body(GO:0016605)
0.0	0.4	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0000942	condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.3	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.0	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.3	GO:0032806	carboxy-terminal domain protein kinase complex(GO:0032806)
0.0	0.3	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.9	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.5	GO:0034708	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	0.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.8	GO:0000922	spindle pole(GO:0000922)
0.0	0.0	GO:1902555	endoribonuclease complex(GO:1902555)
0.0	0.0	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.2	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.5	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.0	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	1.7	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.3	GO:0036064	ciliary basal body(GO:0036064)
0.0	1.6	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0030990	intraciliary transport particle(GO:0030990)
0.0	0.2	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.5	GO:0044450	microtubule organizing center part(GO:0044450)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.7	GO:0000502	proteasome complex(GO:0000502)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.8	GO:0000793	condensed chromosome(GO:0000793)
0.0	0.6	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.3	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.4	GO:0016604	nuclear body(GO:0016604)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	1.2	GO:0005813	centrosome(GO:0005813)
0.0	0.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	1.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.1	GO:0015934	large ribosomal subunit(GO:0015934)
0.0	0.2	GO:0005776	autophagosome(GO:0005776)
0.0	0.7	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.0	GO:0044224	juxtaparanode region of axon(GO:0044224)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.2	0.5	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2	1.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.4	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.4	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.4	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.4	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.7	GO:0005521	lamin binding(GO:0005521)
0.1	0.3	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.4	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.7	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.7	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.3	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	0.3	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.1	0.4	GO:0034452	dynactin binding(GO:0034452)
0.1	1.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	0.2	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1	1.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.4	GO:0070513	death domain binding(GO:0070513)
0.1	0.3	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.1	0.4	GO:0008312	7S RNA binding(GO:0008312)
0.1	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.2	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.2	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	0.4	GO:0031701	angiotensin receptor binding(GO:0031701)
0.1	0.3	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.5	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.1	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.1	0.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	2.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.3	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	0.3	GO:0050733	RS domain binding(GO:0050733)
0.1	0.5	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.1	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.8	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1	0.4	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.4	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	1.0	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.3	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.5	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.6	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.6	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.4	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.4	GO:0030276	clathrin binding(GO:0030276)
0.0	0.4	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.4	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.4	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.5	GO:0019894	kinesin binding(GO:0019894)
0.0	0.7	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.9	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.8	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.4	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.7	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.5	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.8	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.5	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.2	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	1.3	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.0	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	1.1	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.0	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.0	0.2	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.0	GO:0046790	virion binding(GO:0046790)
0.0	0.0	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.8	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.3	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.8	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0044620	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.6	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.3	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.2	GO:0019239	deaminase activity(GO:0019239)
0.0	0.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0032813	death receptor binding(GO:0005123) tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0	0.0	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.2	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.4	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.0	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0015440	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.2	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	2.5	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.0	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.3	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.1	GO:0003924	GTPase activity(GO:0003924)
0.0	0.7	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.4	GO:0008137	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.7	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	2.4	GO:0005096	GTPase activator activity(GO:0005096)
0.0	3.5	GO:0005525	GTP binding(GO:0005525)
0.0	1.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.0	GO:0016803	epoxide hydrolase activity(GO:0004301) ether hydrolase activity(GO:0016803)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	2.4	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	5.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	0.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.5	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.8	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.5	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.6	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.8	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.9	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.7	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.6	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.5	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.7	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.7	PID E2F PATHWAY	E2F transcription factor network
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.3	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.1	PID ATM PATHWAY	ATM pathway
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	PID ATR PATHWAY	ATR signaling pathway
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	1.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	1.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	1.3	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	0.6	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.1	0.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	0.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.8	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.5	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.4	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.8	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	2.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.6	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.6	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.6	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.6	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	2.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.4	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
0.0	0.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.9	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	1.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.6	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	1.1	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.0	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
0.0	0.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.0	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
0.0	0.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling

Results for FOXO3_FOXD2

Z-value: 1.32

Motif logo

Transcription factors associated with FOXO3_FOXD2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the FOXO3_FOXD2 motif across conditions

Conditions sorted by the z-value of the FOXO3_FOXD2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO3_FOXD2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: