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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FOXO4

Z-value: 1.91

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Transcription factors associated with FOXO4

Gene Symbol	Gene ID	Gene Info
FOXO4 Ensembl NCBI GeneCards UniProt	ENSG00000184481.12	FOXO4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
FOXO4	chrX_70317288_70317439	984	0.382171	-0.73	2.7e-02	Click!
FOXO4	chrX_70317051_70317202	747	0.494345	-0.71	3.1e-02	Click!
FOXO4	chrX_70317503_70317654	1199	0.312837	-0.56	1.2e-01	Click!
FOXO4	chrX_70315955_70316925	61	0.950814	-0.47	2.1e-01	Click!
FOXO4	chrX_70315333_70315573	594	0.593661	-0.27	4.8e-01	Click!

Activity of the FOXO4 motif across conditions

Conditions sorted by the z-value of the FOXO4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_44510355_44510599	1.12	ENSG00000266619	.	107099	0.06
chr3_100711576_100712203	1.00	ABI3BP	ABI family, member 3 (NESH) binding protein	408	0.89
chr10_30138566_30138997	0.99	SVIL	supervillin	114048	0.06
chr6_19691587_19692480	0.96	ENSG00000200957	.	49273	0.18
chr1_61668583_61669016	0.93	RP4-802A10.1		78394	0.11
chr4_71589225_71589655	0.88	RUFY3	RUN and FYVE domain containing 3	1068	0.4
chr13_38443188_38443573	0.88	TRPC4	transient receptor potential cation channel, subfamily C, member 4	480	0.86
chr11_114033998_114034413	0.83	ENSG00000221112	.	76554	0.09
chr14_37131505_37132074	0.83	PAX9	paired box 9	10	0.98
chr1_172112919_172113144	0.81	ENSG00000208024	.	753	0.46
chr6_45523679_45523878	0.79	ENSG00000252738	.	90063	0.09
chr4_81188224_81188744	0.78	FGF5	fibroblast growth factor 5	691	0.76
chr3_87039220_87039752	0.78	VGLL3	vestigial like 3 (Drosophila)	366	0.93
chr12_76422565_76423423	0.77	RP11-290L1.3		1280	0.41
chr6_157274340_157274740	0.75	ARID1B	AT rich interactive domain 1B (SWI1-like)	52033	0.17
chr20_9048816_9049419	0.75	PLCB4	phospholipase C, beta 4	293	0.9
chr1_178837029_178837180	0.75	ANGPTL1	angiopoietin-like 1	1309	0.49
chr11_114224558_114224916	0.74	RP11-64D24.2		2556	0.25
chr3_167811230_167811432	0.73	GOLIM4	golgi integral membrane protein 4	1801	0.51
chr10_95239818_95240064	0.71	MYOF	myoferlin	2010	0.32
chr14_35181195_35181456	0.71	CFL2	cofilin 2 (muscle)	1709	0.38
chr22_46472382_46472746	0.70	FLJ27365	hsa-mir-4763	3628	0.12
chr12_10869610_10869831	0.69	YBX3	Y box binding protein 3	6186	0.19
chr12_50796133_50796284	0.68	LARP4	La ribonucleoprotein domain family, member 4	1232	0.46
chr1_158969050_158969253	0.67	IFI16	interferon, gamma-inducible protein 16	607	0.76
chr19_10927638_10927909	0.67	ENSG00000207752	.	399	0.76
chr7_24441857_24442071	0.67	NPY	neuropeptide Y	117238	0.06
chr1_156092284_156092708	0.67	LMNA	lamin A/C	3455	0.14
chr14_29228686_29229081	0.67	RP11-966I7.1		5586	0.17
chr2_68073438_68073697	0.66	C1D	C1D nuclear receptor corepressor	216547	0.02
chr7_19152184_19152434	0.66	AC003986.6		212	0.92
chr6_81938853_81939008	0.66	RP1-300G12.2		305700	0.01
chr6_1612835_1613496	0.65	FOXC1	forkhead box C1	2484	0.42
chr7_116169535_116169759	0.64	CAV1	caveolin 1, caveolae protein, 22kDa	3300	0.2
chr11_122048021_122048203	0.64	ENSG00000207994	.	25096	0.16
chr1_95487209_95487424	0.64	RP11-313A24.1		39836	0.12
chr7_66532196_66532424	0.63	ENSG00000266525	.	47074	0.12
chr2_17699920_17700290	0.63	RAD51AP2	RAD51 associated protein 2	399	0.89
chr13_101046001_101046242	0.63	PCCA	propionyl CoA carboxylase, alpha polypeptide	25368	0.23
chr2_36924555_36924939	0.62	VIT	vitrin	727	0.75
chr1_179110770_179111258	0.62	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	1165	0.52
chr8_6419657_6419902	0.61	ANGPT2	angiopoietin 2	786	0.74
chr2_163099011_163099583	0.61	FAP	fibroblast activation protein, alpha	261	0.94
chr9_134277901_134278052	0.61	PRRC2B	proline-rich coiled-coil 2B	8496	0.22
chr4_48701412_48701950	0.61	FRYL	FRY-like	18493	0.24
chr1_157980267_157980690	0.60	KIRREL-IT1	KIRREL intronic transcript 1 (non-protein coding)	14862	0.2
chr6_105628008_105628228	0.59	POPDC3	popeye domain containing 3	383	0.73
chr6_105936563_105936714	0.59	PREP	prolyl endopeptidase	85679	0.1
chr2_133105207_133105405	0.59	ENSG00000252705	.	59125	0.12
chr4_54063057_54063462	0.59	ENSG00000207385	.	68475	0.13
chrX_14130141_14130292	0.59	ENSG00000264331	.	36206	0.21
chr12_56916774_56917003	0.58	RBMS2	RNA binding motif, single stranded interacting protein 2	1105	0.41
chr21_17677767_17678526	0.58	ENSG00000201025	.	21057	0.28
chr1_210407355_210407517	0.58	SERTAD4-AS1	SERTAD4 antisense RNA 1	44	0.97
chr16_4104228_4104558	0.57	RP11-462G12.4		22380	0.19
chr4_140822945_140823261	0.57	MAML3	mastermind-like 3 (Drosophila)	10982	0.28
chr14_102904620_102904804	0.57	ENSG00000212330	.	63301	0.08
chr10_4805330_4805555	0.57	AKR1E2	aldo-keto reductase family 1, member E2	23379	0.25
chr12_116819288_116819767	0.56	ENSG00000264037	.	46596	0.17
chr10_25009032_25009183	0.56	ARHGAP21	Rho GTPase activating protein 21	1688	0.5
chr4_187857953_187858132	0.56	ENSG00000252382	.	79432	0.12
chr18_53068154_53068339	0.56	TCF4	transcription factor 4	320	0.92
chr6_125932782_125933099	0.56	RP11-624M8.1		133234	0.05
chr3_64252728_64253099	0.55	PRICKLE2	prickle homolog 2 (Drosophila)	742	0.75
chr12_58923400_58923573	0.55	RP11-362K2.2	Protein LOC100506869	14421	0.3
chr5_91977040_91977291	0.55	ENSG00000221810	.	76055	0.13
chr6_73263483_73264009	0.55	KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5	67774	0.12
chr18_32290997_32291170	0.55	DTNA	dystrobrevin, alpha	822	0.73
chr2_69240993_69241361	0.55	ANTXR1	anthrax toxin receptor 1	648	0.74
chr19_13137194_13137536	0.55	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	1554	0.23
chr1_170640082_170640341	0.54	PRRX1	paired related homeobox 1	7133	0.3
chr7_72209303_72209642	0.54	TYW1B	tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)	253	0.92
chr2_151340168_151340387	0.54	RND3	Rho family GTPase 3	1619	0.57
chr9_110513848_110514093	0.54	AL162389.1	Uncharacterized protein	26449	0.19
chr19_23253024_23253175	0.54	ZNF730	zinc finger protein 730	4913	0.29
chr2_66808437_66808694	0.53	MEIS1	Meis homeobox 1	72506	0.12
chr14_103838696_103838951	0.53	MARK3	MAP/microtubule affinity-regulating kinase 3	12906	0.15
chr12_1583558_1583788	0.53	WNT5B	wingless-type MMTV integration site family, member 5B	55384	0.12
chr12_91570174_91570436	0.53	DCN	decorin	2024	0.44
chr1_178065779_178065930	0.53	RASAL2	RAS protein activator like 2	2578	0.43
chr9_16626345_16626809	0.53	RP11-62F24.1		903	0.71
chr11_34998667_34998905	0.53	PDHX	pyruvate dehydrogenase complex, component X	545	0.81
chr3_178684614_178685138	0.53	ZMAT3	zinc finger, matrin-type 3	104478	0.06
chr4_169553568_169553728	0.53	PALLD	palladin, cytoskeletal associated protein	880	0.63
chr2_212025965_212026310	0.53	ENSG00000199585	.	374241	0.01
chr16_69952007_69952311	0.53	WWP2	WW domain containing E3 ubiquitin protein ligase 2	6734	0.17
chr10_79265316_79265521	0.52	ENSG00000199592	.	81389	0.1
chr18_32073953_32074215	0.52	DTNA	dystrobrevin, alpha	217	0.97
chr15_37180001_37180243	0.52	ENSG00000212511	.	35281	0.22
chr3_154797621_154798368	0.52	MME	membrane metallo-endopeptidase	94	0.98
chr6_57127553_57127752	0.51	RAB23	RAB23, member RAS oncogene family	40574	0.15
chr1_182931948_182932121	0.51	ENSG00000264768	.	3324	0.2
chr2_176996093_176996244	0.51	HOXD8	homeobox D8	1083	0.26
chr3_152314332_152314547	0.51	RP11-362A9.3		99837	0.08
chrX_34673939_34674563	0.51	TMEM47	transmembrane protein 47	1154	0.68
chr3_29327656_29328192	0.50	RBMS3-AS3	RBMS3 antisense RNA 3	4293	0.26
chr9_134278352_134278584	0.50	PRRC2B	proline-rich coiled-coil 2B	8988	0.21
chr4_24859806_24860035	0.50	CCDC149	coiled-coil domain containing 149	54588	0.15
chr12_23088184_23088587	0.50	ETNK1	ethanolamine kinase 1	310094	0.01
chr7_73705038_73705189	0.50	CLIP2	CAP-GLY domain containing linker protein 2	1308	0.44
chr2_46165643_46166035	0.50	PRKCE	protein kinase C, epsilon	62202	0.14
chr12_126978117_126978628	0.50	ENSG00000239776	.	672300	0.0
chr10_3977780_3978372	0.50	KLF6	Kruppel-like factor 6	150603	0.04
chr4_140822652_140822941	0.49	MAML3	mastermind-like 3 (Drosophila)	10675	0.28
chr1_24621056_24621364	0.49	ENSG00000266511	.	14865	0.15
chr6_132268442_132268593	0.49	RP11-69I8.3		3569	0.25
chr1_60031328_60031726	0.49	FGGY	FGGY carbohydrate kinase domain containing	11937	0.3
chr2_166326382_166326565	0.49	CSRNP3	cysteine-serine-rich nuclear protein 3	265	0.96
chr5_96880232_96880460	0.49	CTD-2215E18.2		342762	0.01
chr6_128828944_128829440	0.49	RP1-86D1.4		2922	0.22
chr1_161992740_161992891	0.49	OLFML2B	olfactomedin-like 2B	615	0.79
chr7_27680791_27681081	0.49	HIBADH	3-hydroxyisobutyrate dehydrogenase	6439	0.28
chr9_91661673_91661920	0.48	SHC3	SHC (Src homology 2 domain containing) transforming protein 3	4744	0.25
chr8_79468522_79468695	0.48	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	34858	0.19
chr3_100711411_100711562	0.48	ABI3BP	ABI family, member 3 (NESH) binding protein	811	0.72
chr6_27584810_27585278	0.48	ENSG00000238648	.	14144	0.19
chr12_13354322_13354595	0.48	EMP1	epithelial membrane protein 1	4738	0.29
chr4_4261575_4261764	0.48	TMEM128	transmembrane protein 128	11719	0.17
chr12_59434723_59435248	0.48	RP11-150C16.1		120565	0.06
chr4_41157110_41157449	0.48	ENSG00000207198	.	41320	0.14
chr2_169374539_169374694	0.48	CERS6	ceramide synthase 6	61857	0.1
chr13_36491458_36491923	0.48	DCLK1	doublecortin-like kinase 1	61911	0.15
chr3_15836625_15836990	0.47	ANKRD28	ankyrin repeat domain 28	1221	0.51
chr8_25488926_25489082	0.47	CDCA2	cell division cycle associated 2	172289	0.03
chr21_17790454_17790609	0.47	ENSG00000207638	.	120878	0.06
chr5_9540799_9541378	0.47	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	5099	0.2
chr9_91092799_91092950	0.47	NXNL2	nucleoredoxin-like 2	57142	0.14
chr1_196527542_196527719	0.47	ENSG00000265986	.	23981	0.22
chr4_28450970_28451353	0.47	RP11-180C1.1	Uncharacterized protein	46675	0.21
chr2_189158808_189158959	0.47	GULP1	GULP, engulfment adaptor PTB domain containing 1	338	0.89
chr2_153193063_153193456	0.47	FMNL2	formin-like 2	1508	0.52
chr6_84968146_84968306	0.46	KIAA1009	KIAA1009	30873	0.26
chr11_44383183_44383459	0.46	ALX4	ALX homeobox 4	51605	0.17
chr10_70752333_70752623	0.46	KIAA1279	KIAA1279	3991	0.2
chr11_27722222_27723091	0.46	BDNF	brain-derived neurotrophic factor	56	0.98
chr8_85095877_85096048	0.46	RALYL	RALY RNA binding protein-like	193	0.97
chr4_184369530_184369754	0.46	CDKN2AIP	CDKN2A interacting protein	3792	0.23
chr12_32261770_32262117	0.46	RP11-843B15.2		1481	0.38
chr15_40228038_40228378	0.46	EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4	1831	0.28
chr6_11433701_11433852	0.46	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	51195	0.15
chr7_29605545_29606286	0.46	PRR15	proline rich 15	849	0.6
chr12_13351250_13351500	0.46	EMP1	epithelial membrane protein 1	1655	0.47
chr5_35130063_35130359	0.46	PRLR	prolactin receptor	235	0.95
chr2_207077876_207078071	0.46	GPR1	G protein-coupled receptor 1	122	0.95
chr19_41224717_41225149	0.46	ADCK4	aarF domain containing kinase 4	821	0.42
chr8_32407455_32407606	0.46	NRG1	neuregulin 1	1285	0.61
chr5_127277319_127277681	0.45	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	141958	0.05
chr3_72940504_72940835	0.45	GXYLT2	glucoside xylosyltransferase 2	3445	0.28
chr9_132431628_132431910	0.45	PRRX2	paired related homeobox 2	3849	0.16
chr12_91775039_91775202	0.45	DCN	decorin	198220	0.03
chr1_57041430_57041821	0.45	PPAP2B	phosphatidic acid phosphatase type 2B	3616	0.34
chr2_190044545_190044696	0.45	COL5A2	collagen, type V, alpha 2	15	0.98
chr11_122050333_122050506	0.45	ENSG00000207994	.	27403	0.16
chr18_58040359_58040568	0.45	MC4R	melanocortin 4 receptor	462	0.9
chr15_77775145_77775421	0.45	HMG20A	high mobility group 20A	4648	0.29
chr4_173978735_173978902	0.45	ENSG00000241652	.	83976	0.09
chr5_66156448_66156746	0.45	MAST4	microtubule associated serine/threonine kinase family member 4	31907	0.24
chr1_93342801_93342952	0.45	ENSG00000207022	.	31260	0.1
chr7_131242800_131243095	0.45	PODXL	podocalyxin-like	1571	0.52
chr11_69454506_69454752	0.45	CCND1	cyclin D1	1226	0.52
chr3_171581116_171581308	0.44	TMEM212	transmembrane protein 212	19906	0.18
chr2_54587284_54587460	0.44	C2orf73	chromosome 2 open reading frame 73	29280	0.21
chr4_55095564_55095715	0.44	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	179	0.97
chr16_72928743_72929109	0.44	ENSG00000251868	.	73035	0.09
chr5_55193656_55194061	0.44	AC008914.1	Uncharacterized protein	30711	0.14
chr2_175190619_175190960	0.44	SP9	Sp9 transcription factor	8885	0.17
chr11_43757826_43758065	0.44	HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12	55614	0.13
chr16_55513844_55514378	0.43	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	201	0.95
chr19_39465324_39465724	0.43	FBXO17	F-box protein 17	1026	0.37
chr1_225845615_225845788	0.43	ENAH	enabled homolog (Drosophila)	4857	0.23
chr14_52430130_52430293	0.43	AL358333.1	HCG2013195; Uncharacterized protein	6036	0.15
chr18_6088434_6088596	0.43	RP11-793A3.2		63425	0.12
chr3_179907024_179907175	0.43	ENSG00000201822	.	27334	0.25
chr15_99439700_99440117	0.43	RP11-654A16.1		3144	0.27
chr3_55519561_55519953	0.43	WNT5A	wingless-type MMTV integration site family, member 5A	1574	0.4
chr18_25756118_25756718	0.43	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	992	0.73
chr10_3509134_3509315	0.43	RP11-184A2.3		284035	0.01
chr1_179096167_179096689	0.43	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	15751	0.19
chr11_95770968_95771151	0.43	MTMR2	myotubularin related protein 2	113600	0.07
chr2_178107467_178107794	0.43	NFE2L2	nuclear factor, erythroid 2-like 2	10415	0.11
chr21_28214648_28215240	0.43	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	393	0.9
chr2_189377443_189377595	0.43	GULP1	GULP, engulfment adaptor PTB domain containing 1	57246	0.16
chr6_112823116_112823311	0.43	ENSG00000239095	.	25285	0.2
chr15_81619593_81619928	0.43	RP11-761I4.3		2981	0.23
chr1_9953446_9953936	0.43	CTNNBIP1	catenin, beta interacting protein 1	396	0.8
chr10_63697606_63697815	0.42	ENSG00000221272	.	10933	0.26
chr2_179032632_179032866	0.42	ENSG00000223096	.	25474	0.16
chr8_118993051_118993436	0.42	EXT1	exostosin glycosyltransferase 1	129410	0.06
chr10_45473981_45474319	0.42	C10orf10	chromosome 10 open reading frame 10	87	0.95
chr4_68627833_68628061	0.42	GNRHR	gonadotropin-releasing hormone receptor	7869	0.18
chr1_41176173_41176466	0.42	NFYC	nuclear transcription factor Y, gamma	1104	0.44
chr10_114819322_114819557	0.42	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	84240	0.1
chr9_27109032_27109529	0.42	TEK	TEK tyrosine kinase, endothelial	133	0.97
chr6_27264311_27264507	0.42	POM121L2	POM121 transmembrane nucleoporin-like 2	14682	0.2
chr7_79449658_79449850	0.42	ENSG00000206818	.	91770	0.09
chr18_26683567_26683718	0.42	ENSG00000265730	.	7999	0.28
chr10_88519051_88519241	0.42	BMPR1A	bone morphogenetic protein receptor, type IA	2739	0.22
chr9_128411357_128411651	0.42	MAPKAP1	mitogen-activated protein kinase associated protein 1	1192	0.6
chr5_38550048_38550208	0.42	LIFR	leukemia inhibitory factor receptor alpha	6610	0.18
chr4_146972787_146973024	0.42	ENSG00000216055	.	70531	0.11

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	1.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2	0.5	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.2	0.5	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2	0.6	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.8	GO:0014029	neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.7	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.2	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.3	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.9	GO:0060039	pericardium development(GO:0060039)
0.1	0.4	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1	0.3	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.1	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.3	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.3	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.4	GO:0060013	righting reflex(GO:0060013)
0.1	0.4	GO:0070141	response to UV-A(GO:0070141)
0.1	0.4	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.4	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.3	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.4	GO:2000647	negative regulation of stem cell proliferation(GO:2000647)
0.1	2.1	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.2	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.5	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.1	0.3	GO:0030091	protein repair(GO:0030091)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.3	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.6	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.3	GO:0060685	regulation of prostatic bud formation(GO:0060685)
0.1	0.3	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.4	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.2	GO:0071504	cellular response to heparin(GO:0071504)
0.1	1.0	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.1	GO:0060242	contact inhibition(GO:0060242)
0.1	0.5	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1	0.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	1.3	GO:0030325	adrenal gland development(GO:0030325)
0.1	0.4	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	0.3	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.1	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1	0.3	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.3	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.1	GO:0051284	negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	0.3	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.2	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832) micturition(GO:0060073) smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.3	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.1	GO:0050955	thermoception(GO:0050955)
0.1	0.2	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.2	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.2	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.4	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1	1.6	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.1	0.6	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.3	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.2	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.2	GO:0060992	response to fungicide(GO:0060992)
0.1	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.5	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1	0.3	GO:0048844	artery morphogenesis(GO:0048844)
0.1	0.1	GO:0042637	catagen(GO:0042637)
0.1	0.2	GO:0008218	bioluminescence(GO:0008218)
0.1	0.3	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.2	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.1	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	1.1	GO:0007492	endoderm development(GO:0007492)
0.0	0.0	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.3	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.4	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.2	GO:1902692	regulation of neuroblast proliferation(GO:1902692)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.0	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347) regulation of steroid hormone biosynthetic process(GO:0090030)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.4	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.4	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.3	GO:0071456	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.2	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.5	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.0	0.2	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.2	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.2	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.2	GO:0043302	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0060602	branch elongation of an epithelium(GO:0060602)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.2	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.5	GO:0035136	forelimb morphogenesis(GO:0035136)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0060421	positive regulation of heart growth(GO:0060421)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.0	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.3	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.3	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0	0.1	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.3	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0007440	foregut morphogenesis(GO:0007440)
0.0	0.1	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.1	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.4	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.2	GO:0006949	syncytium formation(GO:0006949)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.0	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.1	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.4	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.3	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.1	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0	0.0	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0031034	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0046622	positive regulation of organ growth(GO:0046622)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.2	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.0	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.2	GO:0001678	cellular glucose homeostasis(GO:0001678)
0.0	0.0	GO:0022010	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.0	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.0	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:0014044	Schwann cell development(GO:0014044)
0.0	0.0	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.0	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.0	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.0	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.2	GO:0050807	regulation of synapse organization(GO:0050807)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.0	GO:0001759	organ induction(GO:0001759)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.2	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0070528	protein kinase C signaling(GO:0070528)
0.0	0.1	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.2	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.0	GO:0060534	bronchus development(GO:0060433) trachea cartilage development(GO:0060534)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0071599	otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0072203	cell proliferation involved in metanephros development(GO:0072203)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.3	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.2	GO:0060606	primary neural tube formation(GO:0014020) tube closure(GO:0060606)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.0	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.5	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.0	GO:0021546	rhombomere development(GO:0021546)
0.0	0.0	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0043243	positive regulation of microtubule depolymerization(GO:0031117) positive regulation of protein complex disassembly(GO:0043243) positive regulation of protein depolymerization(GO:1901881)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.9	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.6	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.9	GO:0071437	invadopodium(GO:0071437)
0.2	0.5	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	1.0	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.4	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.7	GO:0016342	catenin complex(GO:0016342)
0.1	0.3	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.2	GO:0044215	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	0.4	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.2	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	1.2	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.4	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.5	GO:0045178	basal part of cell(GO:0045178)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.3	GO:0030315	T-tubule(GO:0030315)
0.0	1.0	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.9	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.3	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.7	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	1.0	GO:0005604	basement membrane(GO:0005604)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.0	1.0	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	2.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.0	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.0	GO:0030016	myofibril(GO:0030016)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.0	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2	0.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.6	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	0.9	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	0.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	0.5	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.4	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	0.4	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.4	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.6	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.3	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	0.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.6	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.8	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.3	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.6	GO:0017166	vinculin binding(GO:0017166)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	2.9	GO:0005518	collagen binding(GO:0005518)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.3	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.2	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.2	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	1.1	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.2	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.8	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.4	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.5	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.8	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.7	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.3	GO:0051378	serotonin binding(GO:0051378)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.3	GO:0008430	selenium binding(GO:0008430)
0.0	0.4	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.5	GO:1990782	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.4	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.4	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	1.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	1.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.3	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.0	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.2	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.1	GO:0016723	ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.0	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	3.9	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.0	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.0	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.5	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.0	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0015250	water channel activity(GO:0015250)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	2.2	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	5.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.5	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.6	PID BMP PATHWAY	BMP receptor signaling
0.0	0.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.4	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.0	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.1	REACTOME PHOSPHOLIPASE C MEDIATED CASCADE	Genes involved in Phospholipase C-mediated cascade
0.1	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.7	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	1.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	2.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.1	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.8	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.8	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.4	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation