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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for FOXO4

Z-value: 1.91

Motif logo

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Transcription factors associated with FOXO4

Gene Symbol Gene ID Gene Info
FOXO4
ENSG00000184481.12 forkhead box O4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chrX_70317288_70317439FOXO49840.382171-0.732.7e-02Click!
chrX_70317051_70317202FOXO47470.494345-0.713.1e-02Click!
chrX_70317503_70317654FOXO411990.312837-0.561.2e-01Click!
chrX_70315955_70316925FOXO4610.950814-0.472.1e-01Click!
chrX_70315333_70315573FOXO45940.593661-0.274.8e-01Click!

Activity of the FOXO4 motif across conditions

Conditions sorted by the z-value of the FOXO4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_44510355_44510599 1.12 ENSG00000266619
 .
 107099
 0.06
chr3_100711576_100712203 1.00 ABI3BP
 ABI family, member 3 (NESH) binding protein
 408
 0.89
chr10_30138566_30138997 0.99 SVIL
 supervillin
 114048
 0.06
chr6_19691587_19692480 0.96 ENSG00000200957
 .
 49273
 0.18
chr1_61668583_61669016 0.93 RP4-802A10.1
78394
 0.11
chr4_71589225_71589655 0.88 RUFY3
 RUN and FYVE domain containing 3
 1068
 0.4
chr13_38443188_38443573 0.88 TRPC4
 transient receptor potential cation channel, subfamily C, member 4
 480
 0.86
chr11_114033998_114034413 0.83 ENSG00000221112
 .
 76554
 0.09
chr14_37131505_37132074 0.83 PAX9
 paired box 9
 10
 0.98
chr1_172112919_172113144 0.81 ENSG00000208024
 .
 753
 0.46
chr6_45523679_45523878 0.79 ENSG00000252738
 .
 90063
 0.09
chr4_81188224_81188744 0.78 FGF5
 fibroblast growth factor 5
 691
 0.76
chr3_87039220_87039752 0.78 VGLL3
 vestigial like 3 (Drosophila)
 366
 0.93
chr12_76422565_76423423 0.77 RP11-290L1.3
1280
 0.41
chr6_157274340_157274740 0.75 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 52033
 0.17
chr20_9048816_9049419 0.75 PLCB4
 phospholipase C, beta 4
 293
 0.9
chr1_178837029_178837180 0.75 ANGPTL1
 angiopoietin-like 1
 1309
 0.49
chr11_114224558_114224916 0.74 RP11-64D24.2
2556
 0.25
chr3_167811230_167811432 0.73 GOLIM4
 golgi integral membrane protein 4
 1801
 0.51
chr10_95239818_95240064 0.71 MYOF
 myoferlin
 2010
 0.32
chr14_35181195_35181456 0.71 CFL2
 cofilin 2 (muscle)
 1709
 0.38
chr22_46472382_46472746 0.70 FLJ27365
 hsa-mir-4763
 3628
 0.12
chr12_10869610_10869831 0.69 YBX3
 Y box binding protein 3
 6186
 0.19
chr12_50796133_50796284 0.68 LARP4
 La ribonucleoprotein domain family, member 4
 1232
 0.46
chr1_158969050_158969253 0.67 IFI16
 interferon, gamma-inducible protein 16
 607
 0.76
chr19_10927638_10927909 0.67 ENSG00000207752
 .
 399
 0.76
chr7_24441857_24442071 0.67 NPY
 neuropeptide Y
 117238
 0.06
chr1_156092284_156092708 0.67 LMNA
 lamin A/C
 3455
 0.14
chr14_29228686_29229081 0.67 RP11-966I7.1
5586
 0.17
chr2_68073438_68073697 0.66 C1D
 C1D nuclear receptor corepressor
 216547
 0.02
chr7_19152184_19152434 0.66 AC003986.6
212
 0.92
chr6_81938853_81939008 0.66 RP1-300G12.2
305700
 0.01
chr6_1612835_1613496 0.65 FOXC1
 forkhead box C1
 2484
 0.42
chr7_116169535_116169759 0.64 CAV1
 caveolin 1, caveolae protein, 22kDa
 3300
 0.2
chr11_122048021_122048203 0.64 ENSG00000207994
 .
 25096
 0.16
chr1_95487209_95487424 0.64 RP11-313A24.1
39836
 0.12
chr7_66532196_66532424 0.63 ENSG00000266525
 .
 47074
 0.12
chr2_17699920_17700290 0.63 RAD51AP2
 RAD51 associated protein 2
 399
 0.89
chr13_101046001_101046242 0.63 PCCA
 propionyl CoA carboxylase, alpha polypeptide
 25368
 0.23
chr2_36924555_36924939 0.62 VIT
 vitrin
 727
 0.75
chr1_179110770_179111258 0.62 ABL2
 c-abl oncogene 2, non-receptor tyrosine kinase
 1165
 0.52
chr8_6419657_6419902 0.61 ANGPT2
 angiopoietin 2
 786
 0.74
chr2_163099011_163099583 0.61 FAP
 fibroblast activation protein, alpha
 261
 0.94
chr9_134277901_134278052 0.61 PRRC2B
 proline-rich coiled-coil 2B
 8496
 0.22
chr4_48701412_48701950 0.61 FRYL
 FRY-like
 18493
 0.24
chr1_157980267_157980690 0.60 KIRREL-IT1
 KIRREL intronic transcript 1 (non-protein coding)
 14862
 0.2
chr6_105628008_105628228 0.59 POPDC3
 popeye domain containing 3
 383
 0.73
chr6_105936563_105936714 0.59 PREP
 prolyl endopeptidase
 85679
 0.1
chr2_133105207_133105405 0.59 ENSG00000252705
 .
 59125
 0.12
chr4_54063057_54063462 0.59 ENSG00000207385
 .
 68475
 0.13
chrX_14130141_14130292 0.59 ENSG00000264331
 .
 36206
 0.21
chr12_56916774_56917003 0.58 RBMS2
 RNA binding motif, single stranded interacting protein 2
 1105
 0.41
chr21_17677767_17678526 0.58 ENSG00000201025
 .
 21057
 0.28
chr1_210407355_210407517 0.58 SERTAD4-AS1
 SERTAD4 antisense RNA 1
 44
 0.97
chr16_4104228_4104558 0.57 RP11-462G12.4
22380
 0.19
chr4_140822945_140823261 0.57 MAML3
 mastermind-like 3 (Drosophila)
 10982
 0.28
chr14_102904620_102904804 0.57 ENSG00000212330
 .
 63301
 0.08
chr10_4805330_4805555 0.57 AKR1E2
 aldo-keto reductase family 1, member E2
 23379
 0.25
chr12_116819288_116819767 0.56 ENSG00000264037
 .
 46596
 0.17
chr10_25009032_25009183 0.56 ARHGAP21
 Rho GTPase activating protein 21
 1688
 0.5
chr4_187857953_187858132 0.56 ENSG00000252382
 .
 79432
 0.12
chr18_53068154_53068339 0.56 TCF4
 transcription factor 4
 320
 0.92
chr6_125932782_125933099 0.56 RP11-624M8.1
133234
 0.05
chr3_64252728_64253099 0.55 PRICKLE2
 prickle homolog 2 (Drosophila)
 742
 0.75
chr12_58923400_58923573 0.55 RP11-362K2.2
 Protein LOC100506869
 14421
 0.3
chr5_91977040_91977291 0.55 ENSG00000221810
 .
 76055
 0.13
chr6_73263483_73264009 0.55 KCNQ5
 potassium voltage-gated channel, KQT-like subfamily, member 5
 67774
 0.12
chr18_32290997_32291170 0.55 DTNA
 dystrobrevin, alpha
 822
 0.73
chr2_69240993_69241361 0.55 ANTXR1
 anthrax toxin receptor 1
 648
 0.74
chr19_13137194_13137536 0.55 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 1554
 0.23
chr1_170640082_170640341 0.54 PRRX1
 paired related homeobox 1
 7133
 0.3
chr7_72209303_72209642 0.54 TYW1B
 tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
 253
 0.92
chr2_151340168_151340387 0.54 RND3
 Rho family GTPase 3
 1619
 0.57
chr9_110513848_110514093 0.54 AL162389.1
 Uncharacterized protein
 26449
 0.19
chr19_23253024_23253175 0.54 ZNF730
 zinc finger protein 730
 4913
 0.29
chr2_66808437_66808694 0.53 MEIS1
 Meis homeobox 1
 72506
 0.12
chr14_103838696_103838951 0.53 MARK3
 MAP/microtubule affinity-regulating kinase 3
 12906
 0.15
chr12_1583558_1583788 0.53 WNT5B
 wingless-type MMTV integration site family, member 5B
 55384
 0.12
chr12_91570174_91570436 0.53 DCN
 decorin
 2024
 0.44
chr1_178065779_178065930 0.53 RASAL2
 RAS protein activator like 2
 2578
 0.43
chr9_16626345_16626809 0.53 RP11-62F24.1
903
 0.71
chr11_34998667_34998905 0.53 PDHX
 pyruvate dehydrogenase complex, component X
 545
 0.81
chr3_178684614_178685138 0.53 ZMAT3
 zinc finger, matrin-type 3
 104478
 0.06
chr4_169553568_169553728 0.53 PALLD
 palladin, cytoskeletal associated protein
 880
 0.63
chr2_212025965_212026310 0.53 ENSG00000199585
 .
 374241
 0.01
chr16_69952007_69952311 0.53 WWP2
 WW domain containing E3 ubiquitin protein ligase 2
 6734
 0.17
chr10_79265316_79265521 0.52 ENSG00000199592
 .
 81389
 0.1
chr18_32073953_32074215 0.52 DTNA
 dystrobrevin, alpha
 217
 0.97
chr15_37180001_37180243 0.52 ENSG00000212511
 .
 35281
 0.22
chr3_154797621_154798368 0.52 MME
 membrane metallo-endopeptidase
 94
 0.98
chr6_57127553_57127752 0.51 RAB23
 RAB23, member RAS oncogene family
 40574
 0.15
chr1_182931948_182932121 0.51 ENSG00000264768
 .
 3324
 0.2
chr2_176996093_176996244 0.51 HOXD8
 homeobox D8
 1083
 0.26
chr3_152314332_152314547 0.51 RP11-362A9.3
99837
 0.08
chrX_34673939_34674563 0.51 TMEM47
 transmembrane protein 47
 1154
 0.68
chr3_29327656_29328192 0.50 RBMS3-AS3
 RBMS3 antisense RNA 3
 4293
 0.26
chr9_134278352_134278584 0.50 PRRC2B
 proline-rich coiled-coil 2B
 8988
 0.21
chr4_24859806_24860035 0.50 CCDC149
 coiled-coil domain containing 149
 54588
 0.15
chr12_23088184_23088587 0.50 ETNK1
 ethanolamine kinase 1
 310094
 0.01
chr7_73705038_73705189 0.50 CLIP2
 CAP-GLY domain containing linker protein 2
 1308
 0.44
chr2_46165643_46166035 0.50 PRKCE
 protein kinase C, epsilon
 62202
 0.14
chr12_126978117_126978628 0.50 ENSG00000239776
 .
 672300
 0.0
chr10_3977780_3978372 0.50 KLF6
 Kruppel-like factor 6
 150603
 0.04
chr4_140822652_140822941 0.49 MAML3
 mastermind-like 3 (Drosophila)
 10675
 0.28
chr1_24621056_24621364 0.49 ENSG00000266511
 .
 14865
 0.15
chr6_132268442_132268593 0.49 RP11-69I8.3
3569
 0.25
chr1_60031328_60031726 0.49 FGGY
 FGGY carbohydrate kinase domain containing
 11937
 0.3
chr2_166326382_166326565 0.49 CSRNP3
 cysteine-serine-rich nuclear protein 3
 265
 0.96
chr5_96880232_96880460 0.49 CTD-2215E18.2
342762
 0.01
chr6_128828944_128829440 0.49 RP1-86D1.4
2922
 0.22
chr1_161992740_161992891 0.49 OLFML2B
 olfactomedin-like 2B
 615
 0.79
chr7_27680791_27681081 0.49 HIBADH
 3-hydroxyisobutyrate dehydrogenase
 6439
 0.28
chr9_91661673_91661920 0.48 SHC3
 SHC (Src homology 2 domain containing) transforming protein 3
 4744
 0.25
chr8_79468522_79468695 0.48 PKIA
 protein kinase (cAMP-dependent, catalytic) inhibitor alpha
 34858
 0.19
chr3_100711411_100711562 0.48 ABI3BP
 ABI family, member 3 (NESH) binding protein
 811
 0.72
chr6_27584810_27585278 0.48 ENSG00000238648
 .
 14144
 0.19
chr12_13354322_13354595 0.48 EMP1
 epithelial membrane protein 1
 4738
 0.29
chr4_4261575_4261764 0.48 TMEM128
 transmembrane protein 128
 11719
 0.17
chr12_59434723_59435248 0.48 RP11-150C16.1
120565
 0.06
chr4_41157110_41157449 0.48 ENSG00000207198
 .
 41320
 0.14
chr2_169374539_169374694 0.48 CERS6
 ceramide synthase 6
 61857
 0.1
chr13_36491458_36491923 0.48 DCLK1
 doublecortin-like kinase 1
 61911
 0.15
chr3_15836625_15836990 0.47 ANKRD28
 ankyrin repeat domain 28
 1221
 0.51
chr8_25488926_25489082 0.47 CDCA2
 cell division cycle associated 2
 172289
 0.03
chr21_17790454_17790609 0.47 ENSG00000207638
 .
 120878
 0.06
chr5_9540799_9541378 0.47 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
 5099
 0.2
chr9_91092799_91092950 0.47 NXNL2
 nucleoredoxin-like 2
 57142
 0.14
chr1_196527542_196527719 0.47 ENSG00000265986
 .
 23981
 0.22
chr4_28450970_28451353 0.47 RP11-180C1.1
 Uncharacterized protein
 46675
 0.21
chr2_189158808_189158959 0.47 GULP1
 GULP, engulfment adaptor PTB domain containing 1
 338
 0.89
chr2_153193063_153193456 0.47 FMNL2
 formin-like 2
 1508
 0.52
chr6_84968146_84968306 0.46 KIAA1009
 KIAA1009
 30873
 0.26
chr11_44383183_44383459 0.46 ALX4
 ALX homeobox 4
 51605
 0.17
chr10_70752333_70752623 0.46 KIAA1279
 KIAA1279
 3991
 0.2
chr11_27722222_27723091 0.46 BDNF
 brain-derived neurotrophic factor
 56
 0.98
chr8_85095877_85096048 0.46 RALYL
 RALY RNA binding protein-like
 193
 0.97
chr4_184369530_184369754 0.46 CDKN2AIP
 CDKN2A interacting protein
 3792
 0.23
chr12_32261770_32262117 0.46 RP11-843B15.2
1481
 0.38
chr15_40228038_40228378 0.46 EIF2AK4
 eukaryotic translation initiation factor 2 alpha kinase 4
 1831
 0.28
chr6_11433701_11433852 0.46 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 51195
 0.15
chr7_29605545_29606286 0.46 PRR15
 proline rich 15
 849
 0.6
chr12_13351250_13351500 0.46 EMP1
 epithelial membrane protein 1
 1655
 0.47
chr5_35130063_35130359 0.46 PRLR
 prolactin receptor
 235
 0.95
chr2_207077876_207078071 0.46 GPR1
 G protein-coupled receptor 1
 122
 0.95
chr19_41224717_41225149 0.46 ADCK4
 aarF domain containing kinase 4
 821
 0.42
chr8_32407455_32407606 0.46 NRG1
 neuregulin 1
 1285
 0.61
chr5_127277319_127277681 0.45 SLC12A2
 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
 141958
 0.05
chr3_72940504_72940835 0.45 GXYLT2
 glucoside xylosyltransferase 2
 3445
 0.28
chr9_132431628_132431910 0.45 PRRX2
 paired related homeobox 2
 3849
 0.16
chr12_91775039_91775202 0.45 DCN
 decorin
 198220
 0.03
chr1_57041430_57041821 0.45 PPAP2B
 phosphatidic acid phosphatase type 2B
 3616
 0.34
chr2_190044545_190044696 0.45 COL5A2
 collagen, type V, alpha 2
 15
 0.98
chr11_122050333_122050506 0.45 ENSG00000207994
 .
 27403
 0.16
chr18_58040359_58040568 0.45 MC4R
 melanocortin 4 receptor
 462
 0.9
chr15_77775145_77775421 0.45 HMG20A
 high mobility group 20A
 4648
 0.29
chr4_173978735_173978902 0.45 ENSG00000241652
 .
 83976
 0.09
chr5_66156448_66156746 0.45 MAST4
 microtubule associated serine/threonine kinase family member 4
 31907
 0.24
chr1_93342801_93342952 0.45 ENSG00000207022
 .
 31260
 0.1
chr7_131242800_131243095 0.45 PODXL
 podocalyxin-like
 1571
 0.52
chr11_69454506_69454752 0.45 CCND1
 cyclin D1
 1226
 0.52
chr3_171581116_171581308 0.44 TMEM212
 transmembrane protein 212
 19906
 0.18
chr2_54587284_54587460 0.44 C2orf73
 chromosome 2 open reading frame 73
 29280
 0.21
chr4_55095564_55095715 0.44 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
 179
 0.97
chr16_72928743_72929109 0.44 ENSG00000251868
 .
 73035
 0.09
chr5_55193656_55194061 0.44 AC008914.1
 Uncharacterized protein
 30711
 0.14
chr2_175190619_175190960 0.44 SP9
 Sp9 transcription factor
 8885
 0.17
chr11_43757826_43758065 0.44 HSD17B12
 hydroxysteroid (17-beta) dehydrogenase 12
 55614
 0.13
chr16_55513844_55514378 0.43 MMP2
 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
 201
 0.95
chr19_39465324_39465724 0.43 FBXO17
 F-box protein 17
 1026
 0.37
chr1_225845615_225845788 0.43 ENAH
 enabled homolog (Drosophila)
 4857
 0.23
chr14_52430130_52430293 0.43 AL358333.1
 HCG2013195; Uncharacterized protein
 6036
 0.15
chr18_6088434_6088596 0.43 RP11-793A3.2
63425
 0.12
chr3_179907024_179907175 0.43 ENSG00000201822
 .
 27334
 0.25
chr15_99439700_99440117 0.43 RP11-654A16.1
3144
 0.27
chr3_55519561_55519953 0.43 WNT5A
 wingless-type MMTV integration site family, member 5A
 1574
 0.4
chr18_25756118_25756718 0.43 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
 992
 0.73
chr10_3509134_3509315 0.43 RP11-184A2.3
284035
 0.01
chr1_179096167_179096689 0.43 ABL2
 c-abl oncogene 2, non-receptor tyrosine kinase
 15751
 0.19
chr11_95770968_95771151 0.43 MTMR2
 myotubularin related protein 2
 113600
 0.07
chr2_178107467_178107794 0.43 NFE2L2
 nuclear factor, erythroid 2-like 2
 10415
 0.11
chr21_28214648_28215240 0.43 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 393
 0.9
chr2_189377443_189377595 0.43 GULP1
 GULP, engulfment adaptor PTB domain containing 1
 57246
 0.16
chr6_112823116_112823311 0.43 ENSG00000239095
 .
 25285
 0.2
chr15_81619593_81619928 0.43 RP11-761I4.3
2981
 0.23
chr1_9953446_9953936 0.43 CTNNBIP1
 catenin, beta interacting protein 1
 396
 0.8
chr10_63697606_63697815 0.42 ENSG00000221272
 .
 10933
 0.26
chr2_179032632_179032866 0.42 ENSG00000223096
 .
 25474
 0.16
chr8_118993051_118993436 0.42 EXT1
 exostosin glycosyltransferase 1
 129410
 0.06
chr10_45473981_45474319 0.42 C10orf10
 chromosome 10 open reading frame 10
 87
 0.95
chr4_68627833_68628061 0.42 GNRHR
 gonadotropin-releasing hormone receptor
 7869
 0.18
chr1_41176173_41176466 0.42 NFYC
 nuclear transcription factor Y, gamma
 1104
 0.44
chr10_114819322_114819557 0.42 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
 84240
 0.1
chr9_27109032_27109529 0.42 TEK
 TEK tyrosine kinase, endothelial
 133
 0.97
chr6_27264311_27264507 0.42 POM121L2
 POM121 transmembrane nucleoporin-like 2
 14682
 0.2
chr7_79449658_79449850 0.42 ENSG00000206818
 .
 91770
 0.09
chr18_26683567_26683718 0.42 ENSG00000265730
 .
 7999
 0.28
chr10_88519051_88519241 0.42 BMPR1A
 bone morphogenetic protein receptor, type IA
 2739
 0.22
chr9_128411357_128411651 0.42 MAPKAP1
 mitogen-activated protein kinase associated protein 1
 1192
 0.6
chr5_38550048_38550208 0.42 LIFR
 leukemia inhibitory factor receptor alpha
 6610
 0.18
chr4_146972787_146973024 0.42 ENSG00000216055
 .
 70531
 0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2 0.5 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.2 0.5 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.8 GO:0014029 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.7 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.2 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.3 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.9 GO:0060039 pericardium development(GO:0060039)
0.1 0.4 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1 0.3 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.3 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.4 GO:0060013 righting reflex(GO:0060013)
0.1 0.4 GO:0070141 response to UV-A(GO:0070141)
0.1 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.4 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.3 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.4 GO:2000647 negative regulation of stem cell proliferation(GO:2000647)
0.1 2.1 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.5 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 0.3 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.3 GO:0060685 regulation of prostatic bud formation(GO:0060685)
0.1 0.3 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.4 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.2 GO:0071504 cellular response to heparin(GO:0071504)
0.1 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.1 GO:0060242 contact inhibition(GO:0060242)
0.1 0.5 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 0.2 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 1.3 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.3 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.1 GO:0051284 negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1 0.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.2 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832) micturition(GO:0060073) smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 0.1 GO:0050955 thermoception(GO:0050955)
0.1 0.2 GO:0008049 male courtship behavior(GO:0008049)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.2 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.1 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.4 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1 1.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.1 0.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.2 GO:0060992 response to fungicide(GO:0060992)
0.1 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.5 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1 0.3 GO:0048844 artery morphogenesis(GO:0048844)
0.1 0.1 GO:0042637 catagen(GO:0042637)
0.1 0.2 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.2 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 1.1 GO:0007492 endoderm development(GO:0007492)
0.0 0.0 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.2 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.4 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.2 GO:1902692 regulation of neuroblast proliferation(GO:1902692)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347) regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.0 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.4 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.4 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.3 GO:0071456 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.2 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0003179 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0060602 branch elongation of an epithelium(GO:0060602)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.2 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.5 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0060421 positive regulation of heart growth(GO:0060421)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.0 0.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0 0.1 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0007440 foregut morphogenesis(GO:0007440)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.1 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.1 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.2 GO:0006949 syncytium formation(GO:0006949)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0 0.0 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0046622 positive regulation of organ growth(GO:0046622)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 0.0 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.0 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.0 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.0 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0014044 Schwann cell development(GO:0014044)
0.0 0.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.0 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.0 GO:0071732 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.0 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.2 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.0 GO:0001759 organ induction(GO:0001759)
0.0 0.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0070528 protein kinase C signaling(GO:0070528)
0.0 0.1 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0060534 bronchus development(GO:0060433) trachea cartilage development(GO:0060534)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0071599 otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0072203 cell proliferation involved in metanephros development(GO:0072203)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.0 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.2 GO:0060606 primary neural tube formation(GO:0014020) tube closure(GO:0060606)
0.0 0.0 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.0 0.0 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.5 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.0 GO:0021546 rhombomere development(GO:0021546)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0043243 positive regulation of microtubule depolymerization(GO:0031117) positive regulation of protein complex disassembly(GO:0043243) positive regulation of protein depolymerization(GO:1901881)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.0 GO:0060712 spongiotrophoblast layer development(GO:0060712)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.9 GO:0071437 invadopodium(GO:0071437)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.7 GO:0016342 catenin complex(GO:0016342)
0.1 0.3 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0044215 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 1.2 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.4 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0045178 basal part of cell(GO:0045178)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.7 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0043205 fibril(GO:0043205)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.0 GO:0030016 myofibril(GO:0030016)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.5 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.6 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.6 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 2.9 GO:0005518 collagen binding(GO:0005518)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.2 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.4 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.5 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0016723 ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.0 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 3.9 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.0 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.0 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 5.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 0.1 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
0.1 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 2.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.8 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation